RLF

General Information

Gene Name       : RLF
Gene ID             : ENSG00000117000.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: RLF)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RLFENSG00000117000.89.247.648.44ENCSR000AEF
HepG2RLFENSG00000117000.85.429.927.67ENCSR985KAT
K562RLFENSG00000117000.812.7714.6613.71ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RLF is not avaliable on ENCORE database.



Proteins bound to RNA
  • RLF RNA is bound by 32 proteins.  







eCLIP assay for RLF is not avaliable on ENCORE database.





32 proteins are bound to RLF RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr14070645040706532+3'-UTR3.853768.82556K562ZC3H11A
chr14070645640706517+3'-UTR3.645348.96355K562FAM120A
chr14062705640627184+5'-UTR,CDS3.130146.02012K562NCBP2
chr14062705940627153+5'-UTR,CDS4.1600212.32966HepG2NCBP2
chr14070202640702104+CDS4.446573.02060K562LIN28B
chr14070295540703030+CDS3.948828.51432HepG2BCLAF1
chr14068824240688272+CDS,intron-Proximal3.135433.18789HepG2BCLAF1
chr14070360040703720+CDS3.022384.79228K562SAFB
chr14070322240703294+CDS3.873083.56169K562RBM15
chr14070236140702405+CDS5.009987.08889K562RBM15
chr14070385240703944+CDS4.051516.36204K562IGF2BP1
chr14070276240702815+CDS3.877155.01178K562PUM2
chr14070252840702594+CDS5.189219.50640K562RBM15
chr14070474940704818+CDS3.700659.11737K562PUM2
chr14070167040701734+CDS3.6493513.09223K562RBM15
chr14070343140703555+CDS5.5287511.48733K562IGF2BP1
chr14070145140701517+CDS,intron-Proximal3.970666.48906K562U2AF2
chr14070176640701813+CDS3.039794.21733K562RBM15
chr14068837640688413+CDS,intron-Proximal4.977366.15361K562PRPF8
chr14070147840701527+CDS3.423908.33085K562RBM15
chr14062729140627373+CDS,intron-Proximal5.212337.02967HepG2PRPF8
chr14070416840704249+CDS3.144364.07771K562ZNF622
chr14070486140704900+CDS4.397833.85494HepG2HLTF
chr14070541240705511+CDS5.3937229.54283K562PUM2
chr14070145340701499+CDS,intron-Proximal3.960275.54624K562U2AF1
chr14070176640701842+CDS3.586773.18236K562FXR1
chr14070431840704393+CDS4.731486.05696K562IGF2BP1
chr14068833340688393+CDS,intron-Proximal4.522214.16174HepG2PRPF8
chr14065645940656524+CDS3.319365.63425HepG2BCLAF1
chr14070254440702603+CDS4.397454.80170K562SAFB
chr14070447340704570+CDS5.014129.86393K562YBX3
chr14062716840627261+CDS3.648393.01533HepG2SRSF1
chr14062729640627374+CDS,intron-Proximal3.389753.40058K562PRPF8
chr14070254440702595+CDS3.441775.39683HepG2HLTF
chr14062711740627151+CDS4.267633.98353K562RBM15
chr14070419640704263+CDS3.485123.24890K562SAFB2
chr14070462240704679+CDS3.908216.22361HepG2HLTF
chr14070517040705198+CDS5.320815.45041K562PUM2
chr14070163440701670+CDS4.015336.75060K562RBM15
chr14068832440688369+CDS3.495385.15500HepG2BCLAF1
chr14070156740701616+CDS4.316068.03807K562RBM15
chr14062718140627261+CDS3.551123.86355HepG2PPIG
chr14070295740703037+CDS3.383363.24890K562SAFB2
chr14070350840703548+CDS4.091105.33504HepG2HLTF
chr14066130340661380+CDS,intron-Proximal4.416557.97334HepG2BCLAF1
chr14069732940697334+CDS,intron-Proximal3.281387.02925K562AQR
chr14070401740704089+CDS3.086286.29653HepG2HLTF
chr14070272240702771+CDS3.975155.60474K562RBM15
chr14066661740666676+intron-Distal4.0824322.07427K562AGGF1
chr14068855840688602+intron-Distal3.050724.07440K562PRPF8
chr14066658240666619+intron-Distal4.742325.84190HepG2HNRNPL
chr14069217540692275+intron-Distal3.294803.35585HepG2QKI
chr14067171640671825+intron-Distal3.664834.80214K562HNRNPK
chr14066646140666525+intron-Distal3.6927615.29688K562AGGF1
chr14068806240688082+intron-Distal4.414825.62025K562KHSRP
chr14063128540631389+intron-Distal3.274784.13232K562MATR3
chr14066671340666734+intron-Distal3.147456.05755K562HNRNPL
chr14069212140692231+intron-Distal3.870743.20552HepG2KHSRP
chr14062912440629251+intron-Distal3.385378.00700K562KHSRP
chr14067230340672446+intron-Distal3.316617.64417K562MATR3
chr14066836440668507+intron-Distal,intron-Proximal4.827017.27881HepG2KHSRP
chr14067954740679645+intron-Distal3.121493.53952HepG2KHSRP
chr14066651140666572+intron-Distal3.9480712.50909HepG2HNRNPL
chr14066673440666767+intron-Distal5.188689.08942K562HNRNPL
chr14062840940628490+intron-Distal4.893007.17216HepG2QKI
chr14066667540666763+intron-Distal4.265504.51091HepG2HNRNPL
chr14064252240642603+intron-Distal3.054156.62024K562KHSRP
chr14066661940666674+intron-Distal6.2604917.19070HepG2HNRNPL
chr14064873540648835+intron-Distal3.028263.18966K562MATR3
chr14066683140666891+intron-Distal4.4367512.19994K562HNRNPL
chr14066848440668549+intron-Distal3.214267.67081K562KHSRP
chr14068846540688540+intron-Distal,intron-Proximal3.0913811.69424K562EFTUD2
chr14066658740666629+intron-Distal4.6728311.40582K562HNRNPL
chr14068622540686336+intron-Distal4.072443.84494HepG2QKI
chr14068800440688029+intron-Distal4.3864010.06297K562KHSRP
chr14065684840656953+intron-Distal3.755746.01086HepG2HNRNPL
chr14067894440679029+intron-Distal4.483675.54597K562TARDBP
chr14065691840656958+intron-Distal4.614106.55010K562HNRNPL
chr14066651540666565+intron-Distal3.356586.88340K562HNRNPL
chr14068841940688529+intron-Distal,intron-Proximal3.454784.02462K562TIA1
chr14066649840666511+intron-Distal4.340704.68586HepG2HNRNPL
chr14069447640694529+intron-Distal3.141837.33428K562ILF3
chr14062759840627645+intron-Distal4.995404.34633HepG2EFTUD2
chr14066645940666515+intron-Distal3.796398.83560K562HNRNPL
chr14068797840688004+intron-Distal3.479094.30679K562KHSRP
chr14068802940688062+intron-Distal5.4747611.62275K562KHSRP
chr14063340040633490+intron-Distal3.876194.58716HepG2QKI
chr14065766840657747+intron-Distal5.033038.76210HepG2HNRNPL
chr14065761140657750+intron-Distal3.3957710.65504K562HNRNPL
chr14066836740668524+intron-Distal,intron-Proximal5.184887.79404K562PRPF8
chr14066845140668484+intron-Distal3.6894612.83520K562KHSRP
chr14069217540692268+intron-Distal4.066844.93238K562QKI
chr14063654940636671+intron-Distal3.136247.55882K562KHSRP
chr14066662940666671+intron-Distal4.4278713.03691K562HNRNPL
chr14066841940668451+intron-Distal3.5073910.51920K562KHSRP
chr14065686340656918+intron-Distal3.711178.61569K562HNRNPL
chr14067955940679698+intron-Distal5.3130021.96855K562KHSRP
chr14069736540697371+intron-Proximal4.339459.80019K562AQR
chr14068840340688462+intron-Proximal3.343297.06369K562EFTUD2
chr14065655040656605+intron-Proximal4.671074.86719K562RBM22
chr14068840940688462+intron-Proximal4.310654.36029K562GPKOW
chr14068841340688468+intron-Proximal5.7318713.12143K562PRPF8
chr14062734240627384+intron-Proximal4.464705.98353HepG2EFTUD2
chr14069733440697365+intron-Proximal4.0032910.08968K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RLF is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RLF is not available on ENCORE database.

  • 101 RBPs can affect the levels of RLF.  








The Knockdown/knockout RNA-Seq assay for RLF is not available on ENCORE database.





101 RBPs can affect the gene expression of RLF :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RLFENSG00000117000.8719.770601061.96580-0.561104.419603.24950HepG2ABCF1
RLFENSG00000117000.81180.795701507.27150-0.352202.037701.57310HepG2AKAP1
RLFENSG00000117000.8551.76040991.07030-0.8449019.0957017.69520HepG2CKAP4
RLFENSG00000117000.8710.167201161.02630-0.709204.624503.63160HepG2CNOT7
RLFENSG00000117000.8874.025201132.23380-0.373404.207603.44580HepG2CELF1
RLFENSG00000117000.8694.31980916.76340-0.400905.228004.13000HepG2DDX19B
RLFENSG00000117000.8783.232801443.91180-0.8825011.155509.97880HepG2DDX3X
RLFENSG00000117000.81295.04550830.759100.640402.336501.43930HepG2DDX59
RLFENSG00000117000.8699.03730948.34090-0.440003.119202.40680HepG2DKC1
RLFENSG00000117000.8541.49120827.73130-0.612209.977508.83110HepG2DNAJC2
RLFENSG00000117000.8459.19100873.40260-0.927603.416402.39910HepG2EEF2
RLFENSG00000117000.8419.06160728.27840-0.797302.419201.38450HepG2EFTUD2
RLFENSG00000117000.8557.86510805.65590-0.530204.766603.25400HepG2EIF2S2
RLFENSG00000117000.8382.85950709.10900-0.889203.409502.41200HepG2EIF3D
RLFENSG00000117000.8634.255901317.79090-1.0550013.5516012.15850HepG2EIF4A3
RLFENSG00000117000.8764.535101282.92560-0.746805.925204.94680HepG2EIF4B
RLFENSG00000117000.81418.692901201.077200.240102.232901.46660HepG2EIF4G1
RLFENSG00000117000.8984.611801416.90230-0.525108.154407.21580HepG2ETF1
RLFENSG00000117000.8618.53250968.65670-0.647107.710106.32420HepG2EWSR1
RLFENSG00000117000.8770.234701072.34810-0.477403.268702.43820HepG2FIP1L1
RLFENSG00000117000.8968.59850680.235200.509804.947203.90890HepG2FUBP3
RLFENSG00000117000.8832.752701329.39160-0.674806.955305.89070HepG2FXR1
RLFENSG00000117000.8831.391401233.31300-0.568904.787603.92360HepG2G3BP1
RLFENSG00000117000.8906.696401309.17950-0.530004.746503.56550HepG2G3BP2
RLFENSG00000117000.8763.293701074.81940-0.493802.760101.64880HepG2GRSF1
RLFENSG00000117000.8781.10130946.36870-0.276902.505901.57160HepG2HDGF
RLFENSG00000117000.8479.86340843.06660-0.813009.701708.60060HepG2HNRNPA1
RLFENSG00000117000.8695.68020958.92540-0.463002.786701.37950HepG2HNRNPAB
RLFENSG00000117000.8623.97150937.76870-0.587805.653804.69050HepG2HNRNPC
RLFENSG00000117000.8668.505401005.69400-0.589203.966202.14200HepG2HNRNPD
RLFENSG00000117000.8891.508501248.59040-0.486004.288603.43500HepG2HNRNPK
RLFENSG00000117000.8630.45420931.56780-0.563308.199607.19630HepG2HNRNPU
RLFENSG00000117000.8757.582801178.19710-0.637103.155201.83300HepG2HSPD1
RLFENSG00000117000.8689.508301253.67400-0.8625010.708609.47480HepG2IGF2BP2
RLFENSG00000117000.8611.81450951.56340-0.6372012.7332011.28590HepG2ILF2
RLFENSG00000117000.8770.216201131.91610-0.555403.410601.92340HepG2ILF3
RLFENSG00000117000.8706.337301106.54550-0.647605.202303.49770HepG2KHDRBS1
RLFENSG00000117000.81056.842801733.96770-0.714303.889102.90090HepG2LARP4
RLFENSG00000117000.8494.59840850.86720-0.782708.879806.96490HepG2LARP7
RLFENSG00000117000.8526.34860893.53380-0.763508.320206.30670HepG2LIN28B
RLFENSG00000117000.8569.20620853.71390-0.584804.267302.17180HepG2LSM11
RLFENSG00000117000.8957.775801337.33100-0.481603.470802.77090HepG2MATR3
RLFENSG00000117000.8418.96490742.21780-0.825003.002301.90520HepG2METAP2
RLFENSG00000117000.8913.800401368.85970-0.583005.151304.29920HepG2NCBP2
RLFENSG00000117000.8991.239201207.26400-0.284402.517901.79240HepG2NOL12
RLFENSG00000117000.8917.17750701.740100.386202.596701.87120HepG2NSUN2
RLFENSG00000117000.8746.73360922.07630-0.304302.770501.92170HepG2PARN
RLFENSG00000117000.8990.398901213.03510-0.292502.565301.97510HepG2PCBP1
RLFENSG00000117000.81052.28020779.442500.432905.355104.31400HepG2PRPF4
RLFENSG00000117000.8346.96430584.43320-0.752303.394102.50760HepG2PRPF8
RLFENSG00000117000.8913.632401234.32860-0.434006.127805.37640HepG2PTBP1
RLFENSG00000117000.8847.910201152.42030-0.442703.822403.13470HepG2PUF60
RLFENSG00000117000.8827.422501223.32290-0.5641011.4510010.41590HepG2PUM1
RLFENSG00000117000.8740.195601009.62520-0.447806.157505.30360HepG2PUS1
RLFENSG00000117000.8671.519401042.73830-0.634903.290702.52430HepG2RAVER1
RLFENSG00000117000.8851.549501184.27620-0.475806.110705.41450HepG2RBM22
RLFENSG00000117000.8789.324001025.99140-0.378302.238901.35570HepG2RBM27
RLFENSG00000117000.81098.822301373.67260-0.322103.530202.93530HepG2NELFE
RLFENSG00000117000.8952.647301279.41940-0.425505.670804.82740HepG2RECQL
RLFENSG00000117000.8299.36440689.89870-1.204505.551904.71460HepG2RPS19
RLFENSG00000117000.8702.87520946.26460-0.429002.929802.10780HepG2RPS2
RLFENSG00000117000.8720.373201166.08750-0.694905.429204.30240HepG2RPS3A
RLFENSG00000117000.8641.37780829.59460-0.371202.284001.68980HepG2SAFB2
RLFENSG00000117000.8437.32700692.57200-0.663302.253101.40090HepG2SERBP1
RLFENSG00000117000.81732.119501315.165800.397202.128601.53560HepG2SF3A3
RLFENSG00000117000.81349.52880783.333000.7847010.571409.27580HepG2SF3B1
RLFENSG00000117000.8856.724701285.05950-0.584909.906708.88960HepG2SF3B4
RLFENSG00000117000.8638.89850967.43460-0.5986010.694309.56260HepG2SMN1
RLFENSG00000117000.8762.553501062.26340-0.478202.497101.59090HepG2SMNDC1
RLFENSG00000117000.81369.65290871.596900.652004.300303.31780HepG2SNRNP70
RLFENSG00000117000.8849.973601341.33860-0.6582012.6865011.83390HepG2SRSF1
RLFENSG00000117000.8911.299401137.82070-0.320303.488702.80080HepG2SRSF5
RLFENSG00000117000.81283.509601091.262900.234002.370101.85170HepG2SRSF9
RLFENSG00000117000.8915.451701294.03830-0.499308.649107.65120HepG2SUCLG1
RLFENSG00000117000.8414.07460905.14330-1.1283021.3479020.20080HepG2TIAL1
RLFENSG00000117000.8681.52650913.28710-0.422305.027104.31240HepG2TRIM56
RLFENSG00000117000.81401.47100917.367800.611306.691405.72630HepG2U2AF1
RLFENSG00000117000.8275.58750445.39630-0.692603.006902.21820HepG2UCHL5
RLFENSG00000117000.8892.696901166.35190-0.385805.111704.20800HepG2UPF1
RLFENSG00000117000.8756.572401126.06560-0.573709.498108.49630HepG2UTP3
RLFENSG00000117000.8915.39800769.212000.250902.252701.63840HepG2ZC3H8
RLFENSG00000117000.81088.329601282.76260-0.237102.679802.13980HepG2ZNF622
RLFENSG00000117000.81090.106601787.18920-0.7132016.8772015.59840K562AGGF1
RLFENSG00000117000.81454.784101825.95850-0.327804.118602.24490K562AKAP1
RLFENSG00000117000.816640.545603306.907302.33100126.47360123.18430K562AQR
RLFENSG00000117000.83043.896002378.123600.356002.769501.35550K562BUD13
RLFENSG00000117000.82659.537603474.33010-0.385606.804905.03670K562CPEB4
RLFENSG00000117000.81134.948001850.12960-0.7050011.924309.57820K562DDX3X
RLFENSG00000117000.81456.454401875.77550-0.365004.657802.82020K562DDX6
RLFENSG00000117000.81681.119102330.61100-0.471308.410307.25870K562EIF2S2
RLFENSG00000117000.83211.287201932.910900.7323012.6627010.86390K562EIF4A3
RLFENSG00000117000.81361.458601740.67400-0.354504.193902.72300K562EIF4B
RLFENSG00000117000.81919.746602454.28930-0.354403.179202.26790K562FIP1L1
RLFENSG00000117000.82916.872701995.683500.547404.380503.44690K562G3BP2
RLFENSG00000117000.82605.521903105.68090-0.253302.295901.60400K562GRSF1
RLFENSG00000117000.81216.620002018.81430-0.730608.444506.67240K562HNRNPM
RLFENSG00000117000.82010.762303327.31820-0.7266011.6380010.03670K562HSPD1
RLFENSG00000117000.81921.558102529.76140-0.396702.439801.49450K562IGF2BP2
RLFENSG00000117000.83448.621102660.304400.374303.038902.15710K562MAGOH
RLFENSG00000117000.81586.058201930.15220-0.283302.664501.45930K562NCBP2
RLFENSG00000117000.81068.461901745.50150-0.708103.509102.35570K562PABPN1
RLFENSG00000117000.83316.518104320.28590-0.381504.076002.36440K562PNPT1
RLFENSG00000117000.82217.955902786.28600-0.329102.777701.95560K562PPIG
RLFENSG00000117000.81247.603302075.31810-0.734203.385501.71140K562PPP1R8
RLFENSG00000117000.82226.143901737.935000.357102.255401.57440K562PRPF8
RLFENSG00000117000.81942.503602584.53100-0.412002.285101.67420K562PTBP1
RLFENSG00000117000.86715.456404587.573800.549708.266506.85400K562PUF60
RLFENSG00000117000.81310.547501844.31690-0.492905.438204.70920K562PUS1
RLFENSG00000117000.81532.273001796.95800-0.229902.013501.49280K562RBM15
RLFENSG00000117000.82556.091101894.237800.432205.519203.55640K562RBM25
RLFENSG00000117000.81089.942601600.15620-0.554006.901505.20360K562SAFB
RLFENSG00000117000.83361.333202667.026700.333705.188504.09730K562SF3A3
RLFENSG00000117000.82778.268002117.403600.391802.943901.93920K562SF3B1
RLFENSG00000117000.83181.549802732.415700.219503.326602.31120K562SRPK2
RLFENSG00000117000.81565.047902392.26710-0.612203.580302.35720K562SRSF5
RLFENSG00000117000.83702.281002944.984500.330102.611101.40180K562STAU1
RLFENSG00000117000.81784.985202473.62750-0.470702.681701.87700K562TIA1
RLFENSG00000117000.81125.247601493.53770-0.408503.557202.45990K562TRIM56
RLFENSG00000117000.82838.492001998.875600.505808.230006.82980K562U2AF2
RLFENSG00000117000.83070.004902550.107700.267604.422503.37050K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RLF is not available on ENCORE database.





3 RBPs can affect the splicing of RLF :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERLFENSG00000117000.8chr1+4066759940667688406613034066143640668083406682860.150000.000480.04500includedK562XRCC6
SERLFENSG00000117000.8chr1+4066759940667688406613034066143640668083406682860.120000.000300.01574includedK562PTBP1
A3SSRLFENSG00000117000.8chr1+4068822740688330406882454068833040668229406682860.199000.000000.00000longerK562AQR
MXERLFENSG00000117000.8chr1+40661303406614364066808340668286406564434065652540688245406883820.180000.000100.001181includedK562AQR
MXERLFENSG00000117000.8chr1+40688227406883824069713440697330406680834066828640701463407065930.195000.000000.000011includedK562AQR
MXERLFENSG00000117000.8chr1+40688227406883824069718840697330406680834066828640701463407065930.188000.000000.000011includedK562AQR
MXERLFENSG00000117000.8chr1+40688227406883304069713440697330406680834066828640701463407065930.195000.000000.000001includedK562AQR
MXERLFENSG00000117000.8chr1+40688227406883304069718840697330406680834066828640701463407065930.187000.000000.000001includedK562AQR
MXERLFENSG00000117000.8chr1+4068824540688330406971344069733040668083406682864070146340706593-0.125000.007370.049442includedK562AQR
MXERLFENSG00000117000.8chr1+4068824540688330406971884069730440668083406682864070146340706593-0.076000.006770.046222includedK562AQR
MXERLFENSG00000117000.8chr1+4068824540688330406971884069733040668083406682864070146340706593-0.136000.003330.025562includedK562AQR
MXERLFENSG00000117000.8chr1+4068824540688382406971344069733040668083406682864070146340706593-0.134000.002470.019902includedK562AQR
MXERLFENSG00000117000.8chr1+4068824540688382406971884069730440668083406682864070146340706593-0.065000.004640.033692includedK562AQR
MXERLFENSG00000117000.8chr1+4068824540688382406971884069733040668083406682864070146340706593-0.146000.000970.008902includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RLF is not avaliable on ENCORE database.