PVR

General Information

Gene Name       : PVR
Gene ID             : ENSG00000073008.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PVR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PVRENSG00000073008.141.711.431.57ENCSR000AEF
HepG2PVRENSG00000073008.1435.5131.0533.28ENCSR985KAT
K562PVRENSG00000073008.1410.029.439.72ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PVR is not avaliable on ENCORE database.



Proteins bound to RNA
  • PVR RNA is bound by 19 proteins.  







eCLIP assay for PVR is not avaliable on ENCORE database.





19 proteins are bound to PVR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr194515711145157200+3'-UTR,CDS,intron-Proximal3.253547.86366HepG2BUD13
chr194516635345166398+3'-UTR,intron-Distal4.055163.36882K562SLTM
chr194516099145161055+3'-UTR,CDS,intron-Distal,intron-Proximal3.840886.68812HepG2BUD13
chr194516558745165647+3'-UTR,5'-UTR3.391494.00430HepG2UPF1
chr194516663245166723+3'-UTR,intron-Distal3.217764.66189HepG2UPF1
chr194516665545166767+3'-UTR,intron-Distal3.487478.67958HepG2SLTM
chr194516611345166205+3'-UTR,intron-Distal4.834916.96152HepG2UPF1
chr194516652245166600+3'-UTR,intron-Distal3.096015.69310HepG2HLTF
chr194516668445166753+3'-UTR,intron-Distal3.858664.49353K562SLTM
chr194516589045165909+3'-UTR,intron-Distal3.089503.07152HepG2HLTF
chr194516094045161082+3'-UTR,CDS,intron-Distal,intron-Proximal4.688278.01338K562AQR
chr194516553045165571+3'-UTR,5'-UTR3.416405.54154HepG2LIN28B
chr194516664845166822+3'-UTR,intron-Distal3.1291915.95676HepG2HLTF
chr194516593045165999+3'-UTR,intron-Distal4.089916.88279HepG2LIN28B
chr194516091045161081+3'-UTR,CDS,intron-Distal,intron-Proximal6.0462413.95436HepG2AQR
chr194516542045165450+3'-UTR4.529354.71804HepG2HLTF
chr194516666845166754+3'-UTR,intron-Distal3.977448.08603HepG2BCLAF1
chr194516097745161076+3'-UTR,CDS,intron-Distal,intron-Proximal3.690915.37652K562BUD13
chr194516096245161050+3'-UTR,CDS,intron-Distal,intron-Proximal3.478484.52919HepG2SF3B4
chr194515329745153378+5'-UTR,CDS,intron-Proximal3.513427.36645HepG2PPIG
chr194515334545153375+5'-UTR,CDS3.406383.68471HepG2BCLAF1
chr194514724745147413+5'-UTR,CDS3.5175912.03336HepG2RPS3
chr194514739345147461+5'-UTR,CDS4.2027412.55615HepG2DDX3X
chr194514724145147388+5'-UTR4.5405638.78888HepG2DDX3X
chr194514718345147341+5'-UTR3.223947.52205HepG2NCBP2
chr194515063245150672+5'-UTR,CDS3.206263.30795HepG2SND1
chr194515310945153246+5'-UTR,CDS3.7453310.37257HepG2SND1
chr194515335345153390+5'-UTR,CDS,intron-Proximal3.309515.76243HepG2BUD13
chr194515337045153438+5'-UTR,CDS,intron-Proximal4.647619.76577HepG2PRPF8
chr194515048245150566+CDS,intron-Proximal3.050976.53290HepG2BUD13
chr194515732345157401+intron-Distal,intron-Proximal3.226933.90917HepG2PRPF4
chr194515748845157631+intron-Distal7.3072841.97273K562AKAP8L
chr194515108745151185+intron-Distal4.058733.90256HepG2PRPF4
chr194515636645156426+intron-Distal4.618655.57507HepG2HNRNPL
chr194515652045156654+intron-Distal5.3970210.83979HepG2HNRNPL
chr194515752945157639+intron-Distal3.766449.08354HepG2FAM120A
chr194515642645156520+intron-Distal4.2879510.00670HepG2HNRNPL
chr194515754145157624+intron-Distal4.050367.53528HepG2EFTUD2
chr194516064545160804+intron-Distal3.030446.26873HepG2PRPF4
chr194515752545157609+intron-Distal5.6451813.74349HepG2PRPF4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PVR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PVR is not available on ENCORE database.

  • 95 RBPs can affect the levels of PVR.  








The Knockdown/knockout RNA-Seq assay for PVR is not available on ENCORE database.





95 RBPs can affect the gene expression of PVR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PVRENSG00000073008.10689.16530937.43450-0.443903.602002.38590HepG2AATF
PVRENSG00000073008.101118.107501553.17070-0.474203.956302.84420HepG2ABCF1
PVRENSG00000073008.101896.330401401.280500.436404.309702.58570HepG2ATP5C1
PVRENSG00000073008.102028.448301545.767000.392006.280305.31240HepG2AUH
PVRENSG00000073008.101262.23840907.425800.476003.149302.18820HepG2BCLAF1
PVRENSG00000073008.101344.569901063.674000.338003.044802.23820HepG2CALR
PVRENSG00000073008.10997.613601326.84310-0.411406.686805.73460HepG2CKAP4
PVRENSG00000073008.101613.723001278.856100.335402.842301.72250HepG2CPSF7
PVRENSG00000073008.102622.265901391.350600.9142025.0181023.48530HepG2CELF1
PVRENSG00000073008.10877.875601227.47250-0.483608.515307.19490HepG2DDX19B
PVRENSG00000073008.10623.14280821.15360-0.398103.186001.73050HepG2DDX52
PVRENSG00000073008.102077.904701256.520700.725609.945008.17620HepG2DDX5
PVRENSG00000073008.101403.33670870.529700.688809.298807.61750HepG2DHX30
PVRENSG00000073008.10918.378901269.80420-0.467406.709005.74220HepG2DKC1
PVRENSG00000073008.101275.47220902.574300.498807.006205.92810HepG2DNAJC21
PVRENSG00000073008.102105.428701227.785500.778009.993308.90660HepG2EIF2S1
PVRENSG00000073008.101566.799401178.051900.411304.166502.74260HepG2EIF2S2
PVRENSG00000073008.101041.66680795.231700.389302.564501.69000HepG2EIF3D
PVRENSG00000073008.10769.92880976.60940-0.343102.717601.64500HepG2EIF3G
PVRENSG00000073008.101789.249501413.810700.339702.862402.03470HepG2EIF4G2
PVRENSG00000073008.10959.329001345.30170-0.487804.796203.40030HepG2ESF1
PVRENSG00000073008.10777.31270985.50010-0.342402.554601.45090HepG2FASTKD2
PVRENSG00000073008.101683.665701111.986100.598407.720206.44530HepG2FUBP3
PVRENSG00000073008.101037.453901369.23740-0.400302.981402.26230HepG2FXR1
PVRENSG00000073008.101054.055901348.49210-0.355402.462301.62410HepG2G3BP2
PVRENSG00000073008.101565.91420865.132800.855905.221403.81690HepG2GNB2L1
PVRENSG00000073008.10563.346701013.56140-0.8473010.967909.66770HepG2HNRNPC
PVRENSG00000073008.101293.024601540.88020-0.253002.741202.02660HepG2HNRNPF
PVRENSG00000073008.102138.587301290.843600.728209.211108.05900HepG2IGF2BP2
PVRENSG00000073008.101859.256401269.069700.550906.973405.74760HepG2MSI2
PVRENSG00000073008.101415.99750899.183600.655002.997202.07040HepG2PABPC1
PVRENSG00000073008.102059.656301255.235600.714308.456307.20870HepG2PABPC4
PVRENSG00000073008.101196.424601450.28070-0.277602.954902.33060HepG2PCBP1
PVRENSG00000073008.101124.423601475.79280-0.392305.252404.54830HepG2PTBP1
PVRENSG00000073008.101222.631801503.20500-0.298103.878003.20150HepG2PUM1
PVRENSG00000073008.102141.201701502.074600.511405.180704.27630HepG2PUM2
PVRENSG00000073008.10961.554901351.89320-0.491508.642407.65580HepG2PUS1
PVRENSG00000073008.101980.176701598.153900.309103.468502.77970HepG2QKI
PVRENSG00000073008.102026.025101045.417900.954507.456106.33080HepG2RAVER1
PVRENSG00000073008.101241.389301483.33140-0.256902.257601.77660HepG2RBM22
PVRENSG00000073008.102077.032801450.490200.517907.116306.07550HepG2RBM25
PVRENSG00000073008.10863.029201642.35090-0.9283024.4522023.16310HepG2NELFE
PVRENSG00000073008.10930.692101529.74420-0.7169015.4240014.16090HepG2RECQL
PVRENSG00000073008.10670.47650896.65600-0.419405.096204.27000HepG2SAFB2
PVRENSG00000073008.101055.58610776.599900.442703.507202.44480HepG2SERBP1
PVRENSG00000073008.102307.061601727.223700.417502.549201.90210HepG2SF3A3
PVRENSG00000073008.101743.504801265.081900.462704.555203.66730HepG2SF3B1
PVRENSG00000073008.101135.088301536.35100-0.436706.328205.49460HepG2SF3B4
PVRENSG00000073008.101626.356101357.836000.260203.674702.88520HepG2SLBP
PVRENSG00000073008.101234.191001045.655900.239102.676502.04080HepG2SMN1
PVRENSG00000073008.102762.648501407.627300.972709.638708.18980HepG2SNRNP70
PVRENSG00000073008.101772.819101398.162100.342405.124504.31370HepG2SRSF5
PVRENSG00000073008.101688.543701304.724100.371906.083305.32160HepG2SRSF9
PVRENSG00000073008.10889.748501454.66080-0.7092015.9891014.96510HepG2SSB
PVRENSG00000073008.101657.834201047.329300.662505.662203.95630HepG2STAU1
PVRENSG00000073008.101723.917901058.811700.7031011.028109.26690HepG2SUPT6H
PVRENSG00000073008.101659.365201022.199400.698906.493705.52340HepG2SUPV3L1
PVRENSG00000073008.101127.523501441.60380-0.354503.174502.57960HepG2TAF15
PVRENSG00000073008.101689.797101245.796000.439704.160803.29390HepG2TARDBP
PVRENSG00000073008.10499.65740685.10940-0.455403.219202.14950HepG2TFIP11
PVRENSG00000073008.10665.17810978.36650-0.556606.413905.71110HepG2TIAL1
PVRENSG00000073008.101384.12850987.098100.487608.175007.28700HepG2TRIM56
PVRENSG00000073008.102630.759401341.453300.9716017.3242015.69940HepG2U2AF1
PVRENSG00000073008.102486.441401164.036101.094803.776002.61300HepG2U2AF2
PVRENSG00000073008.101738.842201478.875800.233502.671102.08290HepG2UTP3
PVRENSG00000073008.10605.314001006.24500-0.733207.800606.59480HepG2XRN2
PVRENSG00000073008.102331.419401684.668000.4686012.2315011.28580HepG2ZNF622
PVRENSG00000073008.10339.49350203.275100.739904.890703.26510K562AARS
PVRENSG00000073008.10312.77620476.78830-0.608205.184304.44780K562AGGF1
PVRENSG00000073008.10396.51970523.92310-0.402002.374101.47480K562AKAP8
PVRENSG00000073008.10284.19770496.12100-0.803807.102706.01510K562AKAP8L
PVRENSG00000073008.10349.11700520.55260-0.576305.028903.75710K562ATP5C1
PVRENSG00000073008.10295.76420199.134700.570603.246302.20510K562BCLAF1
PVRENSG00000073008.10854.40160336.167001.3456012.089909.90200K562CNOT7
PVRENSG00000073008.10490.07710335.392100.547103.200802.00400K562CPEB4
PVRENSG00000073008.10505.24450238.130301.0851012.5956010.91260K562CPSF6
PVRENSG00000073008.10384.31680559.40330-0.541603.867602.12560K562DDX19B
PVRENSG00000073008.10292.25690533.85430-0.8692010.575908.63770K562DKC1
PVRENSG00000073008.10874.21360289.425301.5947040.8008038.67760K562EIF2S2
PVRENSG00000073008.10315.11210211.474000.575303.210402.32970K562EIF4A3
PVRENSG00000073008.10482.14950242.263600.992809.269407.65330K562FMR1
PVRENSG00000073008.10332.00200205.328000.693202.266801.44400K562FTO
PVRENSG00000073008.10417.31540227.367500.876007.327406.03520K562GPKOW
PVRENSG00000073008.10563.26670385.711400.546204.029703.12050K562GRSF1
PVRENSG00000073008.10132.10890212.70000-0.687103.054301.75370K562HNRNPK
PVRENSG00000073008.10225.31770313.68820-0.477402.510701.50870K562HNRNPL
PVRENSG00000073008.10687.26820394.697700.800008.034706.69520K562HSPD1
PVRENSG00000073008.10292.43980526.50430-0.848305.585904.32100K562KIF1C
PVRENSG00000073008.10390.40770194.112901.008006.590305.07960K562KRR1
PVRENSG00000073008.10507.39770221.931101.1929014.1181012.08180K562METAP2
PVRENSG00000073008.10649.00390426.466800.605705.435603.85570K562MSI2
PVRENSG00000073008.10448.86730338.171800.408402.587701.80420K562MTPAP
PVRENSG00000073008.10236.65430413.42030-0.804804.602203.37450K562NAA15
PVRENSG00000073008.10596.83920437.591100.447703.151301.54880K562NOL12
PVRENSG00000073008.10153.00020269.73820-0.818002.624101.66640K562PABPN1
PVRENSG00000073008.10597.65000411.095100.539704.228702.49330K562PNPT1
PVRENSG00000073008.10333.02450217.471000.614704.180603.38070K562PTBP1
PVRENSG00000073008.10665.47990454.949700.548605.702404.30680K562PUM2
PVRENSG00000073008.10193.42140492.00750-1.3469014.3198013.12680K562PUS1
PVRENSG00000073008.10239.42040479.39420-1.0017011.1890010.01680K562RBM15
PVRENSG00000073008.10135.89420219.42000-0.691203.397002.17100K562NELFE
PVRENSG00000073008.10514.88180370.740600.473703.704802.76870K562SF3A3
PVRENSG00000073008.10334.96210216.192000.631603.110402.07790K562SF3B1
PVRENSG00000073008.10205.61400143.766500.516102.251801.48220K562SF3B4
PVRENSG00000073008.10299.01270213.199900.487902.451301.77880K562SRSF1
PVRENSG00000073008.10256.55860181.016400.503102.623501.38250K562SSB
PVRENSG00000073008.10204.34910138.433900.561702.498101.73440K562U2AF2
PVRENSG00000073008.10651.99090492.112100.405802.750001.35410K562UBE2L3
PVRENSG00000073008.10622.31810398.439800.643207.379206.27360K562UPF1
PVRENSG00000073008.10230.57490354.50280-0.620605.202304.07380K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PVR is not available on ENCORE database.





6 RBPs can affect the splicing of PVR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPVRENSG00000073008.10chr19+451620094516216845161029451611784516455845164590-0.353000.000000.00009excludedHepG2U2AF1
SEPVRENSG00000073008.10chr19+4516200945162168451610294516117845164558451645900.141000.000850.09568includedHepG2HNRNPM
SEPVRENSG00000073008.10chr19+4516200945162168451610294516117845164558451645900.111000.004030.08156includedHepG2HNRNPK
SEPVRENSG00000073008.10chr19+4516102945161178451571684515728645164558451645900.071000.001680.02187includedHepG2U2AF2
SEPVRENSG00000073008.10chr19+451620094516216845161066451611784516455845164590-0.354000.000000.00000excludedHepG2SRSF1
SEPVRENSG00000073008.10chr19+451620094516216845161142451611784516455845164590-0.459000.000060.03437excludedHepG2DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PVR is not avaliable on ENCORE database.