PHF8

General Information

Gene Name       : PHF8
Gene ID             : ENSG00000172943.19
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PHF8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PHF8ENSG00000172943.1910.7210.4710.60ENCSR000AEF
HepG2PHF8ENSG00000172943.1916.1215.0615.59ENCSR985KAT
K562PHF8ENSG00000172943.1913.5513.0713.31ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PHF8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PHF8 RNA is bound by 21 proteins.  







eCLIP assay for PHF8 is not avaliable on ENCORE database.





21 proteins are bound to PHF8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX5396549253965545-3'-UTR,intron-Distal,intron-Proximal4.262574.36307HepG2HNRNPK
chrX5396419353964266-3'-UTR,intron-Distal4.116775.25426HepG2PCBP2
chrX5396419453964243-3'-UTR,intron-Distal3.912353.06084HepG2HNRNPK
chrX5396506053965161-3'-UTR,intron-Distal4.046527.31862HepG2HNRNPK
chrX5396549853965597-3'-UTR,CDS,intron-Distal,intron-Proximal3.490163.22654HepG2PCBP2
chrX5396432453964412-3'-UTR,intron-Distal5.6022010.86699HepG2PCBP2
chrX5396399753964046-3'-UTR,intron-Distal3.214824.00631HepG2PTBP1
chrX5406941654069487-5'-UTR,intron-Distal,intron-Proximal4.299665.11005HepG2PRPF4
chrX5407029254070411-5'-UTR,intron-Distal3.905726.48236HepG2DDX3X
chrX5406906154069195-5'-UTR,CDS,intron-Distal,intron-Proximal3.911696.22473K562FMR1
chrX5401231054012381-CDS,intron-Distal,intron-Proximal4.124076.22576HepG2BCLAF1
chrX5404085854040922-CDS,intron-Distal,intron-Proximal4.288667.16838HepG2BCLAF1
chrX5404421454044257-CDS,intron-Distal,intron-Proximal4.190616.65960HepG2BCLAF1
chrX5402207854022197-CDS,intron-Distal,intron-Proximal3.204035.63451HepG2PRPF8
chrX5401160554011647-CDS,intron-Distal4.6741122.16290HepG2U2AF2
chrX5401135254011429-CDS,intron-Distal3.442838.01252K562ZNF622
chrX5404421154044255-CDS,intron-Distal,intron-Proximal3.692754.41267HepG2PPIG
chrX5404925354049276-CDS,intron-Distal3.258643.99124HepG2PPIG
chrX5401134954011423-CDS,intron-Distal3.028925.41277K562UCHL5
chrX5404868454048785-CDS,intron-Distal,intron-Proximal3.454578.99805HepG2BCLAF1
chrX5401161854011656-CDS,intron-Distal4.1072019.05544K562U2AF2
chrX5401421854014305-CDS,intron-Distal,intron-Proximal4.843216.94886HepG2GRWD1
chrX5401135454011463-CDS,intron-Distal3.221196.82013HepG2PPIG
chrX5398927853989369-CDS,intron-Distal4.115478.02029HepG2GRWD1
chrX5404075154040846-CDS,intron-Distal,intron-Proximal4.280038.44604HepG2PRPF8
chrX5401420854014339-CDS,intron-Distal,intron-Proximal3.5128710.92329HepG2BCLAF1
chrX5401421754014263-CDS,intron-Distal,intron-Proximal4.255564.10264K562ZNF622
chrX5401160254011673-CDS,intron-Distal,intron-Proximal4.1321813.98270K562U2AF1
chrX5404867054048792-CDS,intron-Distal,intron-Proximal3.037649.43433HepG2PPIG
chrX5404311054043168-CDS,intron-Distal3.950114.17155HepG2BCLAF1
chrX5404418654044249-CDS,intron-Distal,intron-Proximal3.593165.74135K562DDX24
chrX5401421254014309-CDS,intron-Distal,intron-Proximal3.147915.01560K562UCHL5
chrX5402023454020298-CDS,intron-Distal3.202323.12941K562UCHL5
chrX5401144254011496-CDS,intron-Distal3.239355.04943K562ZNF622
chrX5401231954012367-CDS,intron-Distal,intron-Proximal3.752895.40651HepG2PPIG
chrX5401231054012376-CDS,intron-Distal,intron-Proximal4.720586.15968K562UCHL5
chrX5401164754011671-CDS,intron-Distal,intron-Proximal4.9192020.79907HepG2U2AF2
chrX5404410654044214-CDS,intron-Distal,intron-Proximal4.343618.49795HepG2BCLAF1
chrX5398935053989384-CDS,intron-Distal,intron-Proximal4.227573.77802HepG2U2AF2
chrX5401147454011626-CDS,intron-Distal4.029563.53067K562SRSF1
chrX5401165654011672-CDS,intron-Distal,intron-Proximal4.2653617.77851K562U2AF2
chrX5401218254012280-CDS,intron-Distal,intron-Proximal3.967189.60473K562BUD13
chrX5404871554048775-CDS,intron-Distal,intron-Proximal5.031735.10740K562DDX24
chrX5402859054028659-CDS,intron-Distal5.354968.85296HepG2PPIG
chrX5404412154044211-CDS,intron-Distal,intron-Proximal5.418469.44903HepG2PPIG
chrX5401419854014310-CDS,intron-Distal,intron-Proximal4.473353.71264HepG2FXR2
chrX5398919953989305-CDS,intron-Distal,intron-Proximal3.879544.75655HepG2PRPF8
chrX5401352054013584-CDS,intron-Distal3.107183.80299HepG2GRWD1
chrX5404306254043096-CDS,intron-Distal4.372823.38968HepG2BCLAF1
chrX5401231654012377-CDS,intron-Distal,intron-Proximal3.546535.11891HepG2GRWD1
chrX5406906254069109-CDS,intron-Distal,intron-Proximal3.562485.86107HepG2PPIG
chrX5401227754012383-CDS,intron-Distal,intron-Proximal3.806583.05298K562GRWD1
chrX5401152954011603-CDS,intron-Distal3.222676.73967K562ZNF622
chrX5401161454011672-CDS,intron-Distal,intron-Proximal4.104526.81381K562DDX24
chrX5402902754029078-CDS,intron-Distal,intron-Proximal3.780775.07449K562DDX24
chrX5401151354011595-CDS,intron-Distal3.433616.02862HepG2GRWD1
chrX5397708153977135-intron-Distal3.058033.35050HepG2SUGP2
chrX5401185754011946-intron-Distal3.481414.89507K562SF3B4
chrX5401008654010141-intron-Distal3.414544.23286HepG2QKI
chrX5401037254010425-intron-Distal4.546053.30440HepG2QKI
chrX5401186054011922-intron-Distal3.819928.78792K562BUD13
chrX5401185854011927-intron-Distal3.159535.54854HepG2GRWD1
chrX5401186654011914-intron-Distal4.080345.79432HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PHF8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PHF8 is not available on ENCORE database.

  • 97 RBPs can affect the levels of PHF8.  








The Knockdown/knockout RNA-Seq assay for PHF8 is not available on ENCORE database.





97 RBPs can affect the gene expression of PHF8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PHF8ENSG00000172943.142931.367002301.766300.348702.393401.51660HepG2ABCF1
PHF8ENSG00000172943.14949.556601682.19730-0.8250024.4652023.06330HepG2ACO1
PHF8ENSG00000172943.141352.779702217.78950-0.713207.461706.63260HepG2AKAP1
PHF8ENSG00000172943.141696.488202697.84450-0.669307.567105.90530HepG2AKAP8
PHF8ENSG00000172943.142410.386602061.731300.225302.611601.94230HepG2AUH
PHF8ENSG00000172943.14670.730101054.19190-0.652305.164803.88010HepG2BCCIP
PHF8ENSG00000172943.141968.471101418.965800.472105.038004.26130HepG2BOP1
PHF8ENSG00000172943.141403.998602033.94750-0.534703.160402.11380HepG2CCAR1
PHF8ENSG00000172943.141644.174401302.665200.335802.573801.90690HepG2CPSF6
PHF8ENSG00000172943.142088.839401641.766600.347406.859205.77000HepG2DAZAP1
PHF8ENSG00000172943.141012.816901555.72530-0.6192014.9707013.37410HepG2DDX19B
PHF8ENSG00000172943.141066.321201304.60310-0.291002.020901.43040HepG2DDX21
PHF8ENSG00000172943.141728.991801277.571600.436405.074103.82990HepG2DDX24
PHF8ENSG00000172943.14653.926601036.48470-0.664505.422904.38560HepG2DDX55
PHF8ENSG00000172943.142451.477601479.279500.728704.579103.33290HepG2DDX59
PHF8ENSG00000172943.141347.065801825.21560-0.438203.195402.53660HepG2DDX6
PHF8ENSG00000172943.141506.954101096.047000.459204.697603.43550HepG2DHX30
PHF8ENSG00000172943.142346.277001619.885300.5344012.3044010.78920HepG2EIF4G1
PHF8ENSG00000172943.142476.405701551.713800.674309.441807.97340HepG2EIF4G2
PHF8ENSG00000172943.141636.151402324.14330-0.506404.316503.37200HepG2FIP1L1
PHF8ENSG00000172943.142200.204001304.945200.753503.326602.20720HepG2FTO
PHF8ENSG00000172943.141038.754201524.13770-0.553103.667702.38530HepG2FUS
PHF8ENSG00000172943.141391.109001956.38210-0.492004.601403.72590HepG2FXR1
PHF8ENSG00000172943.141350.434601814.53300-0.426203.260502.54170HepG2G3BP1
PHF8ENSG00000172943.14891.417801476.61040-0.728107.730906.69530HepG2GPKOW
PHF8ENSG00000172943.141303.556901605.92950-0.301003.803502.67310HepG2HDGF
PHF8ENSG00000172943.141183.280801508.93230-0.350704.088302.98670HepG2HNRNPA2B1
PHF8ENSG00000172943.142091.233601312.933300.6715015.9244014.39320HepG2HNRNPF
PHF8ENSG00000172943.141163.690001495.45970-0.361905.381704.46760HepG2HNRNPL
PHF8ENSG00000172943.14943.046501603.31460-0.7657013.2383011.41750HepG2HNRNPM
PHF8ENSG00000172943.141608.983101267.696700.343804.810804.02940HepG2HNRNPU
PHF8ENSG00000172943.142206.131102937.14260-0.412902.855801.60230HepG2HSPD1
PHF8ENSG00000172943.142129.476301292.853700.719803.628002.80820HepG2IGF2BP1
PHF8ENSG00000172943.141345.749501865.95400-0.471502.811501.47710HepG2ILF3
PHF8ENSG00000172943.141208.694201824.43430-0.594004.929503.27640HepG2KHDRBS1
PHF8ENSG00000172943.14910.261501167.96030-0.359602.829701.68380HepG2LARP7
PHF8ENSG00000172943.14821.139601226.32660-0.578606.118604.34480HepG2LIN28B
PHF8ENSG00000172943.14713.33050988.99280-0.471403.710401.85110HepG2MARK2
PHF8ENSG00000172943.14664.829701967.92890-1.5656030.7725028.84560HepG2MATR3
PHF8ENSG00000172943.14781.734001880.62120-1.2665033.2673031.00250HepG2MSI2
PHF8ENSG00000172943.141570.130402014.20970-0.359302.523301.91680HepG2NCBP2
PHF8ENSG00000172943.141254.011401627.98370-0.376504.097503.16950HepG2NOL12
PHF8ENSG00000172943.141997.068201249.536800.676409.013807.72180HepG2NSUN2
PHF8ENSG00000172943.14843.483101130.68330-0.422804.947903.99120HepG2PPIL4
PHF8ENSG00000172943.141098.066801680.23360-0.6137012.6172011.14360HepG2PRPF4
PHF8ENSG00000172943.141237.070001885.76430-0.6082013.3905012.36760HepG2PTBP1
PHF8ENSG00000172943.141156.446701649.82620-0.5126011.0650010.04570HepG2PUM1
PHF8ENSG00000172943.141384.689201648.57860-0.251701.918101.35350HepG2PUM2
PHF8ENSG00000172943.142402.894802042.318100.234502.229301.65820HepG2QKI
PHF8ENSG00000172943.14676.242701392.27980-1.041808.112206.94470HepG2RAVER1
PHF8ENSG00000172943.141457.565101978.49890-0.440806.663405.94270HepG2RBM22
PHF8ENSG00000172943.141465.823802098.67030-0.5178010.200809.28320HepG2NELFE
PHF8ENSG00000172943.141604.697701954.63410-0.284603.613402.92170HepG2RECQL
PHF8ENSG00000172943.141736.510701414.512800.295801.918601.33750HepG2RPLP0
PHF8ENSG00000172943.142087.172101367.745800.609604.174003.01970HepG2RPS10
PHF8ENSG00000172943.14746.601401021.62740-0.452504.228803.48400HepG2RPS19
PHF8ENSG00000172943.141013.673401298.88900-0.357702.607601.82930HepG2RPS2
PHF8ENSG00000172943.141051.023001325.88850-0.335202.401901.40480HepG2RPS5
PHF8ENSG00000172943.141354.975001128.937200.263203.016202.34950HepG2SAFB2
PHF8ENSG00000172943.141874.380002706.38790-0.530004.229503.38680HepG2SF3A3
PHF8ENSG00000172943.141785.601101394.756300.356303.029802.29260HepG2SF3B1
PHF8ENSG00000172943.141336.030401963.31460-0.5553011.4429010.36860HepG2SF3B4
PHF8ENSG00000172943.142032.044001490.291000.447204.673303.79850HepG2SLBP
PHF8ENSG00000172943.14827.727601316.52680-0.6695016.0132014.65890HepG2SMN1
PHF8ENSG00000172943.142034.353401551.923800.390401.974401.31920HepG2SNRNP70
PHF8ENSG00000172943.141559.783702049.27930-0.393806.699906.04190HepG2SRSF1
PHF8ENSG00000172943.142352.995801289.951000.8671027.2098025.46720HepG2SRSF7
PHF8ENSG00000172943.141401.983301667.20120-0.250002.911902.34900HepG2SRSF9
PHF8ENSG00000172943.142346.127101940.190400.274003.910203.32370HepG2SSB
PHF8ENSG00000172943.141524.810101745.12520-0.194701.877901.34700HepG2SUCLG1
PHF8ENSG00000172943.141997.460301569.039800.348202.684801.75590HepG2SUPT6H
PHF8ENSG00000172943.141592.864001841.98280-0.209601.803601.33180HepG2TAF15
PHF8ENSG00000172943.141041.401701231.78640-0.242201.733601.31810HepG2TIAL1
PHF8ENSG00000172943.141003.170101398.08260-0.478902.808301.32790HepG2TRA2A
PHF8ENSG00000172943.142007.187901518.412700.402504.774303.59340HepG2TUFM
PHF8ENSG00000172943.142616.538601987.932300.396303.432402.73810HepG2U2AF1
PHF8ENSG00000172943.141140.581301607.28940-0.494903.654202.68570HepG2UBE2L3
PHF8ENSG00000172943.141468.427402400.15660-0.7089015.3658013.97470HepG2UPF1
PHF8ENSG00000172943.141146.510602317.25030-1.0152037.7167035.87980HepG2UTP3
PHF8ENSG00000172943.14917.368301531.19450-0.739106.043904.51580HepG2XRCC6
PHF8ENSG00000172943.142032.712302639.70680-0.377008.819307.98480HepG2ZNF622
PHF8ENSG00000172943.142039.921101429.413100.513005.283004.06590K562BOP1
PHF8ENSG00000172943.143498.303402507.043400.480602.427101.44290K562CNOT7
PHF8ENSG00000172943.142064.392801519.820400.441702.276701.55870K562CPSF6
PHF8ENSG00000172943.142146.778701546.489300.473104.854403.71760K562FMR1
PHF8ENSG00000172943.141706.559601310.836100.380502.904901.96760K562FTO
PHF8ENSG00000172943.141871.340901560.342900.262102.627301.51520K562GLRX3
PHF8ENSG00000172943.142080.609801239.098500.747607.232205.64170K562KRR1
PHF8ENSG00000172943.141650.022601211.514200.445604.592402.73500K562LARP7
PHF8ENSG00000172943.14996.719101292.79190-0.375203.476902.42710K562MATR3
PHF8ENSG00000172943.141912.339701416.366400.433004.780103.60990K562METAP2
PHF8ENSG00000172943.141495.356101186.703000.333403.253101.91040K562NCBP2
PHF8ENSG00000172943.142201.567101822.755100.272304.757203.81470K562NSUN2
PHF8ENSG00000172943.14907.007001152.59440-0.345702.609301.65970K562PCBP2
PHF8ENSG00000172943.141537.812001221.628300.332003.021601.52210K562PHF6
PHF8ENSG00000172943.141361.153401121.929700.278702.177201.38360K562PSIP1
PHF8ENSG00000172943.14949.801301258.62180-0.406104.109203.31530K562PTBP1
PHF8ENSG00000172943.142124.566902787.33180-0.391705.672604.10150K562PUM1
PHF8ENSG00000172943.143382.241602732.910300.307402.851502.30230K562PUS1
PHF8ENSG00000172943.143057.336002662.796200.199201.938901.42720K562RBM15
PHF8ENSG00000172943.141337.972901023.506600.386403.897802.71920K562RCC2
PHF8ENSG00000172943.143133.557701894.532200.725902.815801.59980K562SF1
PHF8ENSG00000172943.141985.974101380.124500.524904.686303.39800K562SF3B1
PHF8ENSG00000172943.141253.39640970.268100.369302.942301.87470K562SRFBP1
PHF8ENSG00000172943.142146.377301842.666400.220002.851501.90410K562SRPK2
PHF8ENSG00000172943.142004.959201549.556700.371604.873003.30250K562SRSF7
PHF8ENSG00000172943.141568.582701146.306000.452404.726903.41200K562TRIM56
PHF8ENSG00000172943.142331.605901932.704400.270603.817702.98640K562UPF1
PHF8ENSG00000172943.142614.988702147.647600.283902.465901.65930K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PHF8 is not available on ENCORE database.





7 RBPs can affect the splicing of PHF8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPHF8ENSG00000172943.14chrX-540200335402033654019168540192725402212554022215-0.257000.000020.00067excludedK562SRSF1
SEPHF8ENSG00000172943.14chrX-5402003354020336540191685401927254022125540222150.316000.000010.00022includedHepG2U2AF2
SEPHF8ENSG00000172943.14chrX-540221255402221554020033540203365402630254026394-0.057000.004190.05435excludedK562PUS1
SEPHF8ENSG00000172943.14chrX-540200335402033654019168540192725402212554022215-0.274000.000010.00069excludedHepG2SRSF1
SEPHF8ENSG00000172943.14chrX-540200335402033654019168540192725402212554022215-0.225000.003970.08859excludedHepG2SF3A3
SEPHF8ENSG00000172943.14chrX-540200335402033654019168540192725402212554022215-0.214000.001800.07487excludedHepG2PCBP1
SEPHF8ENSG00000172943.14chrX-540200335402033654019168540192725402212554022215-0.301000.000240.07571excludedHepG2XRN2
SEPHF8ENSG00000172943.14chrX-540200335402033654019168540192725402212554022215-0.355000.000000.00002excludedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PHF8 is not avaliable on ENCORE database.