PGRMC2

General Information

Gene Name       : PGRMC2
Gene ID             : ENSG00000164040.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PGRMC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PGRMC2ENSG00000164040.1636.3026.1631.23ENCSR000AEF
HepG2PGRMC2ENSG00000164040.1632.5979.3355.96ENCSR985KAT
K562PGRMC2ENSG00000164040.1652.0154.6853.34ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PGRMC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PGRMC2 RNA is bound by 28 proteins.  







eCLIP assay for PGRMC2 is not avaliable on ENCORE database.





28 proteins are bound to PGRMC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr4129191981129192038-3'-UTR,intron-Distal,intron-Proximal4.878727.39978HepG2UPF1
chr4129192060129192133-3'-UTR,intron-Distal3.000248.58524K562FAM120A
chr4129193601129193662-3'-UTR,5'-UTR,CDS,intron-Distal3.299613.68457K562LIN28B
chr4129192079129192133-3'-UTR,intron-Distal3.1476813.37914K562UPF1
chr4129191377129191456-3'-UTR,intron-Distal4.569245.59066HepG2IGF2BP1
chr4129191634129191637-3'-UTR,intron-Distal3.901274.73972K562PUM2
chr4129193614129193657-3'-UTR,5'-UTR,CDS,intron-Distal4.834954.87637HepG2SND1
chr4129191976129192055-3'-UTR,intron-Distal,intron-Proximal4.362373.66349K562LIN28B
chr4129191980129192034-3'-UTR,intron-Distal,intron-Proximal3.841669.72842K562UPF1
chr4129191920129191964-3'-UTR,intron-Distal,intron-Proximal3.748577.65557K562FAM120A
chr4129191962129192035-3'-UTR,intron-Distal,intron-Proximal3.803445.36442HepG2FAM120A
chr4129192338129192423-3'-UTR,intron-Distal,intron-Proximal3.296725.58962K562RBM15
chr4129191326129191410-3'-UTR,intron-Distal6.2674322.99716K562TARDBP
chr4129191330129191388-3'-UTR,intron-Distal3.535016.54748K562PABPC4
chr4129193536129193593-3'-UTR,5'-UTR,CDS,intron-Distal4.845545.19012HepG2LIN28B
chr4129191508129191563-3'-UTR,intron-Distal4.235698.19301K562PABPC4
chr4129192492129192560-3'-UTR,CDS,intron-Distal,intron-Proximal3.344958.71292HepG2BCLAF1
chr4129191811129191881-3'-UTR,intron-Distal,intron-Proximal3.157627.46801K562FAM120A
chr4129191965129192050-3'-UTR,intron-Distal,intron-Proximal4.6482212.63005HepG2LIN28B
chr4129192352129192464-3'-UTR,intron-Distal,intron-Proximal3.028055.34387HepG2IGF2BP1
chr4129191763129191879-3'-UTR,intron-Distal,intron-Proximal3.405516.78026HepG2FAM120A
chr4129191753129191811-3'-UTR,intron-Distal,intron-Proximal3.3896411.02323K562FAM120A
chr4129191705129191796-3'-UTR,intron-Distal,intron-Proximal4.3049411.91039HepG2UPF1
chr4129191221129191289-3'-UTR,intron-Distal4.759726.99879HepG2CSTF2
chr4129191616129191656-3'-UTR,intron-Distal3.140943.16269K562IGF2BP1
chr4129191742129191812-3'-UTR,intron-Distal,intron-Proximal3.6416918.52063K562UPF1
chr4129191516129191585-3'-UTR,intron-Distal4.1217913.15612K562PUM2
chr4129191796129191907-3'-UTR,intron-Distal,intron-Proximal3.9482513.65944HepG2UPF1
chr4129191664129191738-3'-UTR,intron-Distal,intron-Proximal3.622807.09618K562FAM120A
chr4129193605129193657-3'-UTR,5'-UTR,CDS,intron-Distal4.267598.70605HepG2LIN28B
chr4129191836129191878-3'-UTR,intron-Distal,intron-Proximal4.630339.04751K562UPF1
chr4129192065129192131-3'-UTR,intron-Distal3.626338.15141HepG2UPF1
chr4129192131129192195-3'-UTR,intron-Distal4.087535.85347HepG2UPF1
chr4129190828129190880-3'-UTR,intron-Distal4.422703.72865HepG2LIN28B
chr4129193514129193539-3'-UTR,CDS,intron-Distal,intron-Proximal4.172005.04010K562TARDBP
chr4129192479129192568-3'-UTR,CDS,intron-Distal,intron-Proximal3.286984.84084K562ZNF800
chr4129192356129192460-3'-UTR,intron-Distal,intron-Proximal4.047423.47194HepG2IGF2BP3
chr4129191658129191748-3'-UTR,intron-Distal,intron-Proximal3.594046.76271K562IGF2BP1
chr4129191308129191399-3'-UTR,intron-Distal5.1315158.75925K562PUM2
chr4129192132129192194-3'-UTR,intron-Distal3.8347011.96641HepG2PTBP1
chr4129191984129192039-3'-UTR,intron-Distal,intron-Proximal3.8397012.03933K562FAM120A
chr4129208879129208962-5'-UTR,CDS,intron-Distal3.143026.74654K562CSTF2T
chr4129208861129208958-5'-UTR,CDS,intron-Distal4.0115911.30564HepG2GTF2F1
chr4129208870129208972-5'-UTR,CDS,intron-Distal,intron-Proximal4.3526916.64551HepG2PRPF4
chr4129208884129208951-5'-UTR,CDS,intron-Distal3.398905.28657K562RBM15
chr4129208879129208959-5'-UTR,CDS,intron-Distal3.841173.88441K562NCBP2
chr4129208870129208955-5'-UTR,CDS,intron-Distal3.260066.32494K562UCHL5
chr4129208790129208834-CDS,intron-Distal4.930666.99833HepG2GTF2F1
chr4129208657129208713-CDS,intron-Distal3.486156.68223HepG2RBM15
chr4129208718129208822-CDS,intron-Distal4.642109.72826K562RBM15
chr4129208645129208730-CDS,intron-Distal3.204267.17181K562DDX51
chr4129208644129208710-CDS,intron-Distal3.055976.93757K562CSTF2T
chr4129208790129208846-CDS,intron-Distal4.4183014.10470HepG2PRPF4
chr4129208779129208871-CDS,intron-Distal4.4345014.07667HepG2RPS3
chr4129208570129208627-CDS,intron-Distal,intron-Proximal4.610036.60283HepG2RPS3
chr4129208519129208527-CDS,intron-Distal3.874884.98250K562AQR
chr4129208643129208715-CDS,intron-Distal4.2687722.98014HepG2PRPF4
chr4129208741129208790-CDS,intron-Distal3.676729.72788HepG2PRPF4
chr4129208638129208722-CDS,intron-Distal,intron-Proximal4.4401728.51691HepG2GRSF1
chr4129208885129208932-CDS,intron-Distal3.130233.76473K562DROSHA
chr4129208591129208640-CDS,intron-Distal,intron-Proximal4.457747.76240HepG2PRPF4
chr4129208640129208707-CDS,intron-Distal,intron-Proximal3.195084.96855HepG2FASTKD2
chr4129208722129208794-CDS,intron-Distal4.4973713.77781HepG2GRSF1
chr4129208575129208621-CDS,intron-Distal,intron-Proximal4.544103.91454K562PUM1
chr4129208482129208519-CDS,intron-Distal4.092934.98250K562AQR
chr4129208491129208545-CDS,intron-Distal,intron-Proximal4.370323.25089HepG2AQR
chr4129208646129208711-CDS,intron-Distal3.269916.72086K562GTF2F1
chr4129208648129208716-CDS,intron-Distal3.7106312.42988HepG2GTF2F1
chr4129208627129208718-CDS,intron-Distal,intron-Proximal3.110159.91439HepG2RPS3
chr4129208643129208718-CDS,intron-Distal3.093678.34643K562RBM15
chr4129208786129208839-CDS,intron-Distal4.178617.13132K562GTF2F1
chr4129208871129208936-CDS,intron-Distal3.021636.32604HepG2RPS3
chr4129202651129202676-intron-Distal3.824174.19039HepG2PTBP1
chr4129202184129202233-intron-Distal3.984063.55640HepG2QKI
chr4129199194129199246-intron-Distal3.899693.82697HepG2HNRNPC
chr4129202587129202653-intron-Distal3.669354.22415K562PTBP1
chr4129202589129202651-intron-Distal5.333347.45191HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PGRMC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PGRMC2 is not available on ENCORE database.

  • 96 RBPs can affect the levels of PGRMC2.  








The Knockdown/knockout RNA-Seq assay for PGRMC2 is not available on ENCORE database.





96 RBPs can affect the gene expression of PGRMC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PGRMC2ENSG00000164040.121284.445302154.46240-0.7462023.5300022.14960HepG2ACO1
PGRMC2ENSG00000164040.122469.201104316.63300-0.8059010.277509.31720HepG2AKAP1
PGRMC2ENSG00000164040.121818.462902164.68780-0.251403.035502.23620HepG2AKAP8L
PGRMC2ENSG00000164040.121884.312202154.11820-0.193102.418801.78870HepG2CKAP4
PGRMC2ENSG00000164040.121318.021801888.13750-0.518602.916502.13100HepG2CNOT7
PGRMC2ENSG00000164040.122084.558902753.29400-0.401404.653803.85900HepG2CELF1
PGRMC2ENSG00000164040.121111.344901835.90070-0.7242011.091209.83930HepG2DDX21
PGRMC2ENSG00000164040.122188.128601796.232700.284602.579101.70020HepG2DDX24
PGRMC2ENSG00000164040.121101.466601656.08650-0.588403.630202.75830HepG2DDX55
PGRMC2ENSG00000164040.122409.269101740.842800.468703.080302.02100HepG2DDX5
PGRMC2ENSG00000164040.122100.167203552.10230-0.758209.258108.19900HepG2DDX6
PGRMC2ENSG00000164040.121750.327101422.437000.299202.378101.46900HepG2DHX30
PGRMC2ENSG00000164040.122765.408902061.268800.423908.313507.26260HepG2DKC1
PGRMC2ENSG00000164040.121222.936401474.79270-0.270202.661401.96850HepG2DNAJC21
PGRMC2ENSG00000164040.121117.997701461.77220-0.386806.545805.60180HepG2DNAJC2
PGRMC2ENSG00000164040.121303.182101696.94080-0.380902.310001.46620HepG2EEF2
PGRMC2ENSG00000164040.122459.710503414.65180-0.473204.621503.86580HepG2EIF2S1
PGRMC2ENSG00000164040.121030.594601377.60310-0.418702.969602.03790HepG2EIF3D
PGRMC2ENSG00000164040.121573.366803674.15280-1.2236017.3781015.75470HepG2EIF4B
PGRMC2ENSG00000164040.121414.613702105.40480-0.573708.242206.81430HepG2EWSR1
PGRMC2ENSG00000164040.121043.200702016.42270-0.9508012.9003011.41970HepG2FIP1L1
PGRMC2ENSG00000164040.121971.999601378.526100.516405.057903.37810HepG2FKBP4
PGRMC2ENSG00000164040.121969.262701619.741500.281802.449601.70980HepG2FUBP3
PGRMC2ENSG00000164040.122081.121803807.46440-0.8715014.1994012.75270HepG2FXR1
PGRMC2ENSG00000164040.122138.489503531.92740-0.723909.023107.85710HepG2G3BP1
PGRMC2ENSG00000164040.121611.548902056.97010-0.352105.377004.06260HepG2HDGF
PGRMC2ENSG00000164040.121054.483201488.92160-0.497705.493204.62570HepG2HNRNPA1
PGRMC2ENSG00000164040.122759.012603576.52290-0.374403.623902.83150HepG2HNRNPK
PGRMC2ENSG00000164040.122206.394901578.429500.483104.702403.90300HepG2HNRNPLL
PGRMC2ENSG00000164040.121135.679901645.20130-0.5347010.497609.38010HepG2HNRNPU
PGRMC2ENSG00000164040.122962.990403590.10780-0.277001.963601.38630HepG2IGF2BP2
PGRMC2ENSG00000164040.122169.889403369.23870-0.634802.468901.54720HepG2IGF2BP3
PGRMC2ENSG00000164040.121872.258702579.12410-0.462102.374201.60820HepG2LARP4
PGRMC2ENSG00000164040.123106.095903808.79410-0.294202.043401.47600HepG2MAGOH
PGRMC2ENSG00000164040.121181.176503830.09470-1.6972041.0335038.83710HepG2MATR3
PGRMC2ENSG00000164040.121015.221701441.83210-0.506102.657401.62540HepG2METAP2
PGRMC2ENSG00000164040.121283.860301631.76150-0.345903.310702.42970HepG2MSI2
PGRMC2ENSG00000164040.122418.835603920.30130-0.696708.709707.61960HepG2NCBP2
PGRMC2ENSG00000164040.122080.909702936.21670-0.496702.577101.84160HepG2NOL12
PGRMC2ENSG00000164040.122490.019501399.645900.8310013.7198012.18840HepG2NSUN2
PGRMC2ENSG00000164040.122726.921903491.22150-0.356502.758902.03830HepG2PABPC4
PGRMC2ENSG00000164040.121323.764201628.46660-0.298903.571902.62120HepG2PARN
PGRMC2ENSG00000164040.122420.420003508.84500-0.5357013.8971012.70380HepG2PCBP1
PGRMC2ENSG00000164040.121625.989503570.47360-1.1348052.4410050.71550HepG2PTBP1
PGRMC2ENSG00000164040.121871.207302974.96450-0.668907.293106.42520HepG2PUM1
PGRMC2ENSG00000164040.121383.942802194.47790-0.6651019.1888017.82950HepG2PUS1
PGRMC2ENSG00000164040.122689.612503866.71370-0.5237010.159109.06790HepG2QKI
PGRMC2ENSG00000164040.121380.050602156.16280-0.643703.734002.91940HepG2RAVER1
PGRMC2ENSG00000164040.121763.265302632.09760-0.578005.023504.37790HepG2RBM22
PGRMC2ENSG00000164040.122540.123403973.51730-0.6455019.8481018.65530HepG2NELFE
PGRMC2ENSG00000164040.122753.054503700.93100-0.426909.385808.35070HepG2RECQL
PGRMC2ENSG00000164040.122907.625302117.528500.457402.627701.70480HepG2RPS10
PGRMC2ENSG00000164040.12672.603701340.41000-0.9948018.6116017.22540HepG2RPS19
PGRMC2ENSG00000164040.121486.342402011.72910-0.436702.784301.70770HepG2RPS5
PGRMC2ENSG00000164040.121025.662101345.40270-0.391502.855901.90070HepG2SERBP1
PGRMC2ENSG00000164040.122313.318301562.280700.566206.862605.79250HepG2SF3B1
PGRMC2ENSG00000164040.122262.246503717.15780-0.7164024.1242022.67050HepG2SF3B4
PGRMC2ENSG00000164040.121055.228901708.58140-0.6952020.4872018.98200HepG2SMN1
PGRMC2ENSG00000164040.122404.854002972.93460-0.305902.853802.34700HepG2SRFBP1
PGRMC2ENSG00000164040.122204.628101577.460400.482804.740602.71560HepG2SRP68
PGRMC2ENSG00000164040.123154.588003879.97580-0.298605.399504.79440HepG2SRSF1
PGRMC2ENSG00000164040.121979.467502766.99050-0.483205.963505.09620HepG2SRSF5
PGRMC2ENSG00000164040.121556.471001277.660300.284703.152002.41470HepG2SRSF7
PGRMC2ENSG00000164040.122304.268503156.62530-0.4541010.874509.90700HepG2SRSF9
PGRMC2ENSG00000164040.123982.895702581.346000.6256016.5213015.48780HepG2SSB
PGRMC2ENSG00000164040.122120.013503147.05220-0.569905.730904.89530HepG2SUCLG1
PGRMC2ENSG00000164040.121883.000601538.722200.291201.970401.34580HepG2TARDBP
PGRMC2ENSG00000164040.122530.773103204.48630-0.340503.800302.82800HepG2TIA1
PGRMC2ENSG00000164040.121131.998301598.61740-0.498005.346304.69770HepG2TIAL1
PGRMC2ENSG00000164040.121185.593401612.91120-0.444107.463206.61380HepG2TRIM56
PGRMC2ENSG00000164040.121076.118801724.80510-0.680608.373807.28070HepG2U2AF1
PGRMC2ENSG00000164040.122367.181602897.64150-0.291702.158901.42470HepG2UBE2L3
PGRMC2ENSG00000164040.121482.527702071.52870-0.4826010.102209.07110HepG2UTP3
PGRMC2ENSG00000164040.122027.968001622.974700.321302.666601.95510HepG2XRN2
PGRMC2ENSG00000164040.121681.187902359.79020-0.4892013.2925012.31910HepG2ZNF622
PGRMC2ENSG00000164040.121357.266501564.57170-0.205101.936101.44540K562AGGF1
PGRMC2ENSG00000164040.122177.481302874.14640-0.400504.316003.61410K562AQR
PGRMC2ENSG00000164040.121739.353802233.18320-0.360604.917503.41530K562CPEB4
PGRMC2ENSG00000164040.121030.108101534.64520-0.575107.894206.55580K562CPSF6
PGRMC2ENSG00000164040.122077.495801751.925000.245802.493501.66740K562DKC1
PGRMC2ENSG00000164040.12924.966201245.09650-0.428802.858101.92940K562EFTUD2
PGRMC2ENSG00000164040.121258.072202062.69360-0.7133016.6790015.13400K562EIF2S2
PGRMC2ENSG00000164040.12957.970301170.24000-0.288802.584401.48140K562EIF4B
PGRMC2ENSG00000164040.121130.857501561.40290-0.465404.136403.08780K562FMR1
PGRMC2ENSG00000164040.12918.069301323.40270-0.527604.553303.35260K562FTO
PGRMC2ENSG00000164040.121610.148301351.411000.252602.469901.89140K562FXR1
PGRMC2ENSG00000164040.122150.880101519.784700.501003.630102.79490K562G3BP2
PGRMC2ENSG00000164040.121128.005101465.23420-0.377403.334402.46410K562GPKOW
PGRMC2ENSG00000164040.121810.731402748.82690-0.602209.607408.17400K562GRSF1
PGRMC2ENSG00000164040.121476.708601810.22910-0.293802.631501.58410K562HNRNPA1
PGRMC2ENSG00000164040.12538.223101100.62790-1.0321017.4301016.01320K562HNRNPC
PGRMC2ENSG00000164040.121812.273702406.45590-0.409103.795802.86800K562HSPD1
PGRMC2ENSG00000164040.121066.566701430.22120-0.423304.155603.06990K562METAP2
PGRMC2ENSG00000164040.121540.534001797.53380-0.222603.087302.30280K562NSUN2
PGRMC2ENSG00000164040.121346.711201692.02880-0.329302.719501.74820K562PCBP2
PGRMC2ENSG00000164040.121394.221801847.44290-0.406104.621103.78430K562PTBP1
PGRMC2ENSG00000164040.123004.360703787.58910-0.334203.036002.03290K562PUM2
PGRMC2ENSG00000164040.121052.016301614.62250-0.618005.635404.89300K562PUS1
PGRMC2ENSG00000164040.121283.307201771.80250-0.465404.835103.68610K562RBM22
PGRMC2ENSG00000164040.121461.500201136.651900.362603.806202.00920K562SRSF9
PGRMC2ENSG00000164040.121423.761801001.637100.507206.498505.23100K562SYNCRIP
PGRMC2ENSG00000164040.121451.133701833.03790-0.337102.590401.90450K562TARDBP
PGRMC2ENSG00000164040.121406.924601768.13420-0.329703.181202.29540K562TIA1
PGRMC2ENSG00000164040.12802.958301008.17000-0.328302.215001.38210K562TRIM56
PGRMC2ENSG00000164040.122106.721001522.059900.468906.634105.39760K562U2AF2
PGRMC2ENSG00000164040.121560.005501905.96540-0.289003.812502.98150K562UPF1
PGRMC2ENSG00000164040.121429.328001921.46600-0.426904.922502.69960K562UPF2
PGRMC2ENSG00000164040.121241.739001630.87090-0.393304.052202.98730K562WDR3
PGRMC2ENSG00000164040.122000.144501695.940400.237903.102502.20840K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PGRMC2 is not available on ENCORE database.





1 RBPs can affect the splicing of PGRMC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPGRMC2ENSG00000164040.12chr4-1292078701292079801291935161291936721292085271292089660.068000.000000.00000includedHepG2U2AF1
SEPGRMC2ENSG00000164040.12chr4-1292078701292079801291935161291936721292085271292089660.281000.000000.00000includedK562U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PGRMC2 is not avaliable on ENCORE database.