PDE4C

General Information

Gene Name       : PDE4C
Gene ID             : ENSG00000105650.22
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PDE4C)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PDE4CENSG00000105650.220.000.100.05ENCSR000AEF
HepG2PDE4CENSG00000105650.221.240.871.05ENCSR985KAT
K562PDE4CENSG00000105650.220.170.040.11ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PDE4C is not avaliable on ENCORE database.



Proteins bound to RNA
  • PDE4C RNA is bound by 1 proteins.  







eCLIP assay for PDE4C is not avaliable on ENCORE database.





1 proteins are bound to PDE4C RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr191833173218331837-CDS,intron-Distal,intron-Proximal3.080403.00054HepG2PRPF4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PDE4C is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PDE4C is not available on ENCORE database.

  • 117 RBPs can affect the levels of PDE4C.  








The Knockdown/knockout RNA-Seq assay for PDE4C is not available on ENCORE database.





117 RBPs can affect the gene expression of PDE4C :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PDE4CENSG00000105650.17121.24980232.00400-0.936204.310002.21480HepG2AARS
PDE4CENSG00000105650.17126.47750317.16570-1.326406.050204.52950HepG2AATF
PDE4CENSG00000105650.17334.76780831.95400-1.3133013.3995012.27330HepG2ACO1
PDE4CENSG00000105650.17171.09810453.59200-1.406604.075303.44730HepG2AKAP1
PDE4CENSG00000105650.17631.23070835.70060-0.404802.242701.54480HepG2AKAP8L
PDE4CENSG00000105650.17219.15270375.26000-0.776002.032601.35560HepG2ASCC1
PDE4CENSG00000105650.171329.07420460.541001.5289045.4102043.23310HepG2AUH
PDE4CENSG00000105650.17478.89510170.146301.4928018.6847017.33600HepG2BOP1
PDE4CENSG00000105650.17839.24990408.286701.0394010.067808.22620HepG2CCAR1
PDE4CENSG00000105650.17126.41480356.53880-1.495904.503103.52940HepG2CIRBP
PDE4CENSG00000105650.17299.81360156.193900.940606.115605.12760HepG2CPSF6
PDE4CENSG00000105650.17467.42010251.775500.8925010.062108.18700HepG2YBX3
PDE4CENSG00000105650.17408.22170146.196001.4813016.6051014.35800HepG2CSTF2
PDE4CENSG00000105650.17231.88240550.90110-1.248409.587608.52750HepG2CELF1
PDE4CENSG00000105650.17819.00280592.441300.467105.679904.67170HepG2DAZAP1
PDE4CENSG00000105650.17309.67170769.34860-1.3129013.9554012.38930HepG2DDX19B
PDE4CENSG00000105650.17131.60380252.12540-0.937906.391404.71080HepG2DDX1
PDE4CENSG00000105650.17556.21650349.348500.670905.799804.85740HepG2DDX21
PDE4CENSG00000105650.17184.36100342.34640-0.892903.618102.56410HepG2DDX24
PDE4CENSG00000105650.17121.01160217.75060-0.847503.707702.24740HepG2DDX27
PDE4CENSG00000105650.17141.91600434.40100-1.614004.849904.04050HepG2DDX3X
PDE4CENSG00000105650.17223.15070322.49790-0.531303.081701.65610HepG2DDX52
PDE4CENSG00000105650.17442.02660177.372901.317208.557006.89490HepG2DDX59
PDE4CENSG00000105650.17310.39160430.32750-0.471302.643301.65180HepG2DDX5
PDE4CENSG00000105650.17871.32670373.408601.222409.504808.43220HepG2DDX6
PDE4CENSG00000105650.17323.84410795.90410-1.2973014.6767013.37530HepG2DKC1
PDE4CENSG00000105650.17167.64860245.04260-0.547603.189902.49780HepG2DNAJC2
PDE4CENSG00000105650.17150.86260384.71920-1.3506012.5881010.83240HepG2EEF2
PDE4CENSG00000105650.17181.76420320.66350-0.819005.472303.90880HepG2EFTUD2
PDE4CENSG00000105650.17619.65500322.105600.943808.199006.35390HepG2AGO1
PDE4CENSG00000105650.17894.90590358.719501.3188018.8332017.38460HepG2EIF2S1
PDE4CENSG00000105650.17157.14630412.88640-1.393605.994004.32200HepG2EIF2S2
PDE4CENSG00000105650.17196.21880312.27160-0.670303.293102.31330HepG2EIF3D
PDE4CENSG00000105650.17938.06560396.307601.2430015.1357013.65730HepG2EIF4A3
PDE4CENSG00000105650.17105.64700386.08940-1.869705.847104.87230HepG2EIF4B
PDE4CENSG00000105650.171188.89870584.404401.0245024.5046022.54500HepG2EIF4G1
PDE4CENSG00000105650.17256.60810528.69130-1.042905.367604.57850HepG2ETF1
PDE4CENSG00000105650.17373.68940812.79460-1.1211010.182808.61490HepG2EWSR1
PDE4CENSG00000105650.17584.49400279.161901.0660014.5409011.92380HepG2FAM120A
PDE4CENSG00000105650.17706.49620333.169801.0843015.4518013.17560HepG2FASTKD2
PDE4CENSG00000105650.17279.62910549.87870-0.975603.400602.55350HepG2FIP1L1
PDE4CENSG00000105650.17398.35450193.712901.040007.534905.59200HepG2FKBP4
PDE4CENSG00000105650.17281.70890156.481800.848102.551401.57910HepG2FTO
PDE4CENSG00000105650.17263.90330413.98930-0.649603.362402.12940HepG2FUS
PDE4CENSG00000105650.17193.88750278.02720-0.520002.366301.54560HepG2GEMIN5
PDE4CENSG00000105650.17644.24960177.031401.8635026.6274024.87920HepG2GPKOW
PDE4CENSG00000105650.17145.31690249.59120-0.780403.920703.17120HepG2HNRNPA1
PDE4CENSG00000105650.17528.75400277.625000.929408.808307.62250HepG2HNRNPC
PDE4CENSG00000105650.17626.96140222.158001.4967025.6659023.79890HepG2HNRNPF
PDE4CENSG00000105650.17357.80330275.789400.375502.218201.66980HepG2HNRNPU
PDE4CENSG00000105650.17978.35070218.755102.1609060.6179058.04000HepG2IGF2BP1
PDE4CENSG00000105650.17619.57330377.118900.716202.101101.50370HepG2IGF2BP2
PDE4CENSG00000105650.17391.58580281.709600.475003.751302.91000HepG2ILF2
PDE4CENSG00000105650.17485.69490282.518000.781604.004102.05490HepG2CCAR2
PDE4CENSG00000105650.171157.69300760.389000.606309.563907.77510HepG2KIF1C
PDE4CENSG00000105650.17199.64120312.56090-0.646702.577201.48100HepG2LARP7
PDE4CENSG00000105650.171198.82780402.542901.574303.877403.14170HepG2MATR3
PDE4CENSG00000105650.17125.10300326.79580-1.385307.805106.13050HepG2METAP2
PDE4CENSG00000105650.17188.99490444.70970-1.234505.625204.50830HepG2MSI2
PDE4CENSG00000105650.17859.12750172.361802.317309.950908.08510HepG2MTPAP
PDE4CENSG00000105650.17161.74610411.97720-1.348803.697802.96960HepG2NCBP2
PDE4CENSG00000105650.17314.25330587.45890-0.9026011.8939010.35920HepG2NOL12
PDE4CENSG00000105650.17510.37750149.822901.7682023.7327021.85820HepG2NSUN2
PDE4CENSG00000105650.17127.51610233.39780-0.872103.908201.99950HepG2PA2G4
PDE4CENSG00000105650.17142.06880272.98310-0.942207.541206.25490HepG2PARN
PDE4CENSG00000105650.1763.34680379.38020-2.5823013.8505012.65840HepG2PCBP1
PDE4CENSG00000105650.17462.24970300.105000.623103.416901.55250HepG2PHF6
PDE4CENSG00000105650.17149.17270258.24710-0.791803.817102.36660HepG2PKM
PDE4CENSG00000105650.1793.86840386.08980-2.0402010.405409.47550HepG2PTBP1
PDE4CENSG00000105650.171067.92210560.756700.9293013.9783012.77960HepG2PUF60
PDE4CENSG00000105650.1761.82200595.23950-3.2673095.3438092.96350HepG2PUM1
PDE4CENSG00000105650.17280.70680594.82240-1.0834015.0109013.52600HepG2PUM2
PDE4CENSG00000105650.17198.60770847.37060-2.0931027.2395025.68010HepG2PUS1
PDE4CENSG00000105650.1753.89550378.20460-2.8109025.5232023.59750HepG2RAVER1
PDE4CENSG00000105650.17192.91940441.90300-1.195706.733806.01000HepG2RBM22
PDE4CENSG00000105650.17209.38750379.42970-0.857703.524402.77060HepG2RBM25
PDE4CENSG00000105650.17119.79440376.87770-1.653509.380907.53700HepG2RBM27
PDE4CENSG00000105650.1766.90110141.08070-1.076404.289302.40070HepG2RBM47
PDE4CENSG00000105650.17219.92360429.63410-0.966104.121303.48410HepG2NELFE
PDE4CENSG00000105650.17180.72320400.23070-1.147104.972504.17640HepG2RECQL
PDE4CENSG00000105650.173795.57390239.424903.9866054.8322052.76790HepG2RPLP0
PDE4CENSG00000105650.171361.16130303.889102.1631067.0595064.75860HepG2RPS19
PDE4CENSG00000105650.17527.73900146.747001.846403.162102.30780HepG2RPS3A
PDE4CENSG00000105650.17116.92570354.80290-1.601408.436706.56020HepG2RPS5
PDE4CENSG00000105650.1778.46370177.56640-1.178305.451804.38300HepG2RRP9
PDE4CENSG00000105650.17447.55020245.602100.8656010.284609.16420HepG2SAFB2
PDE4CENSG00000105650.17100.34070304.94450-1.6036015.1579013.07100HepG2SERBP1
PDE4CENSG00000105650.17199.47240671.50100-1.7512011.035509.62770HepG2SF3A3
PDE4CENSG00000105650.17206.08850401.86830-0.963502.453801.89220HepG2SF3B4
PDE4CENSG00000105650.17382.96730537.61990-0.489404.819503.93370HepG2SLBP
PDE4CENSG00000105650.17149.36950286.41260-0.939208.181307.16780HepG2SMN1
PDE4CENSG00000105650.17176.80560385.58270-1.124908.663006.92170HepG2SMNDC1
PDE4CENSG00000105650.17866.78910186.054302.2199030.2066027.68770HepG2SNRNP70
PDE4CENSG00000105650.17346.38140499.13950-0.527101.920301.48000HepG2SRFBP1
PDE4CENSG00000105650.17126.95210419.50480-1.724408.825108.08820HepG2SRSF1
PDE4CENSG00000105650.1794.80650179.96060-0.924603.273202.17520HepG2SRSF3
PDE4CENSG00000105650.171019.16590553.631500.8803015.4187014.10850HepG2SRSF5
PDE4CENSG00000105650.17423.85630218.287400.957206.158405.18550HepG2SRSF7
PDE4CENSG00000105650.17284.19760629.66070-1.1477010.612109.52630HepG2SUCLG1
PDE4CENSG00000105650.17469.13680231.678501.017807.261806.24930HepG2SUPV3L1
PDE4CENSG00000105650.17255.20310524.62240-1.039605.294003.85520HepG2TBRG4
PDE4CENSG00000105650.178431.53550267.977304.9755099999.9999999999.99999HepG2TIAL1
PDE4CENSG00000105650.17111.30190379.74340-1.7705015.1434012.09880HepG2TRA2A
PDE4CENSG00000105650.17513.50000270.376800.925304.664903.97130HepG2TRIM56
PDE4CENSG00000105650.17106.49980248.11410-1.220208.231105.76610HepG2TROVE2
PDE4CENSG00000105650.17379.99360547.78910-0.527603.177802.23600HepG2TUFM
PDE4CENSG00000105650.17144.91060470.19970-1.698105.432304.56910HepG2U2AF1
PDE4CENSG00000105650.17380.16170579.79570-0.608903.843502.85040HepG2UBE2L3
PDE4CENSG00000105650.1745.24890136.85320-1.596708.493707.16350HepG2UCHL5
PDE4CENSG00000105650.17575.61080212.122001.4401012.9055010.65320HepG2UPF2
PDE4CENSG00000105650.17158.96680574.94730-1.8547012.0434010.93050HepG2UTP3
PDE4CENSG00000105650.17160.17460371.89420-1.215207.763405.70940HepG2XRCC5
PDE4CENSG00000105650.17329.98350228.062400.532902.221501.56610HepG2XRN2
PDE4CENSG00000105650.17480.90530257.334100.902007.364606.35550HepG2ZC3H8
PDE4CENSG00000105650.17228.82130654.95510-1.517209.671708.80570HepG2ZNF622
PDE4CENSG00000105650.17228.04000377.84440-0.728504.159702.53990HepG2ZRANB2
PDE4CENSG00000105650.1731.926905.903502.435003.590602.92220K562HNRNPC
PDE4CENSG00000105650.1730.6305010.606101.530002.274101.59170K562NSUN2
PDE4CENSG00000105650.1722.935505.092302.171102.491301.60850K562TIAL1
PDE4CENSG00000105650.1722.021905.427702.020402.200601.37150K562TRIM56
PDE4CENSG00000105650.1728.429609.622701.562802.280301.48450K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PDE4C is not available on ENCORE database.





1 RBPs can affect the splicing of PDE4C :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPDE4CENSG00000105650.17chr19-1832441418324628183241771832430018327550183277050.516000.000080.00348includedHepG2HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PDE4C is not avaliable on ENCORE database.