PAM

General Information

Gene Name       : PAM
Gene ID             : ENSG00000145730.20
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PAM)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PAMENSG00000145730.2013.9310.7512.34ENCSR000AEF
HepG2PAMENSG00000145730.2029.0037.2133.11ENCSR985KAT
K562PAMENSG00000145730.200.360.520.44ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PAM is not avaliable on ENCORE database.



Proteins bound to RNA
  • PAM RNA is bound by 7 proteins.  







eCLIP assay for PAM is not avaliable on ENCORE database.





7 proteins are bound to PAM RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5102201704102201750+3'-UTR,5'-UTR,intron-Distal5.097718.30262HepG2DDX3X
chr5102201853102201926+3'-UTR,5'-UTR,CDS,intron-Distal3.967717.30917HepG2DDX3X
chr5102201752102201802+3'-UTR,5'-UTR,intron-Distal5.1002411.01919HepG2DDX3X
chr5102285625102285681+3'-UTR,CDS3.650844.51739HepG2BCLAF1
chr5102340899102340933+3'-UTR,CDS,intron-Proximal4.698973.70369HepG2LIN28B
chr5102201546102201681+3'-UTR,5'-UTR,intron-Distal5.2662323.24314HepG2DDX3X
chr5102285604102285625+3'-UTR,CDS,intron-Proximal4.067343.06595HepG2BCLAF1
chr5102342504102342569+3'-UTR,CDS,intron-Proximal4.890645.09917HepG2LIN28B
chr5102364625102364698+3'-UTR,CDS4.538365.09917HepG2LIN28B
chr5102201802102201853+3'-UTR,5'-UTR,intron-Distal4.219686.48775HepG2DDX3X
chr5102365100102365183+3'-UTR3.392293.27682HepG2LARP4
chr5102282545102282586+5'-UTR,CDS4.054103.38968HepG2BCLAF1
chr5102323837102323951+intron-Distal4.338644.51080HepG2HNRNPL
chr5102096702102096811+intron-Distal4.955774.05848HepG2QKI
chr5102300813102300925+intron-Distal3.174773.15317HepG2HNRNPL
chr5102094387102094489+intron-Distal4.294804.05848HepG2QKI
chr5102300926102301025+intron-Distal4.553595.30852HepG2HNRNPL
chr5102104152102104245+intron-Distal5.1180110.10565HepG2QKI
chr5102275008102275084+intron-Distal4.853106.76922HepG2PTBP1
chr5102275792102275882+intron-Distal3.674796.03810HepG2HNRNPL
chr5102116511102116588+intron-Distal6.4223421.40045HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PAM is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PAM is not available on ENCORE database.

  • 105 RBPs can affect the levels of PAM.  








The Knockdown/knockout RNA-Seq assay for PAM is not available on ENCORE database.





105 RBPs can affect the gene expression of PAM :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PAMENSG00000145730.163144.251202262.116500.474905.828304.32520HepG2AATF
PAMENSG00000145730.161631.659002516.41340-0.625006.791405.39330HepG2ABCF1
PAMENSG00000145730.163549.375202442.558900.5391016.1885014.97680HepG2ACO1
PAMENSG00000145730.161906.635902378.16410-0.318802.470601.52790HepG2ADAR
PAMENSG00000145730.165642.472202945.233800.9378013.9627012.86370HepG2AKAP1
PAMENSG00000145730.164518.608802787.934300.696604.541503.21960HepG2AKAP8
PAMENSG00000145730.163912.749102454.015800.6729021.4465019.60950HepG2AKAP8L
PAMENSG00000145730.163643.979302318.707600.6521013.1942011.72310HepG2CALR
PAMENSG00000145730.162629.933403816.52650-0.537204.348203.11200HepG2CCAR1
PAMENSG00000145730.161589.906802315.23470-0.542205.828504.73370HepG2CIRBP
PAMENSG00000145730.161716.516902442.00530-0.5086013.7309012.48230HepG2CKAP4
PAMENSG00000145730.161678.338603598.21580-1.1002011.6594010.12810HepG2CNOT7
PAMENSG00000145730.162530.949101341.524300.9157016.4228014.91400HepG2CPSF6
PAMENSG00000145730.163512.017802315.953800.600605.009203.00140HepG2CSTF2T
PAMENSG00000145730.165334.389303197.785500.7381024.7808023.25360HepG2CELF1
PAMENSG00000145730.161965.240802259.00660-0.201002.543801.74160HepG2DDX19B
PAMENSG00000145730.163466.410902496.247300.473605.929304.97860HepG2DDX21
PAMENSG00000145730.162582.851101700.417600.603005.194004.17480HepG2DDX55
PAMENSG00000145730.164461.069302423.667400.8801012.1686010.98180HepG2DDX6
PAMENSG00000145730.16987.252702336.86110-1.2431052.3242050.35290HepG2DKC1
PAMENSG00000145730.161605.433502334.73370-0.540305.774604.48210HepG2EEF2
PAMENSG00000145730.164828.482902329.769701.0513020.2657018.75890HepG2EIF2S1
PAMENSG00000145730.161360.806902357.05540-0.7925016.4544014.28370HepG2EIF3G
PAMENSG00000145730.161735.219602574.59170-0.569205.182304.30940HepG2EIF4A3
PAMENSG00000145730.163539.812002506.874600.497703.491402.72250HepG2EIF4B
PAMENSG00000145730.162650.916203392.20670-0.355706.613105.42040HepG2EIF4G1
PAMENSG00000145730.161470.645402179.56980-0.567607.169405.51160HepG2ESF1
PAMENSG00000145730.162318.717803246.30320-0.4855011.1416010.06610HepG2ETF1
PAMENSG00000145730.163206.504502386.796300.425805.404604.23850HepG2EWSR1
PAMENSG00000145730.162354.729301693.949200.475106.907405.03500HepG2FAM120A
PAMENSG00000145730.161785.901901415.470500.335302.663001.41660HepG2FKBP4
PAMENSG00000145730.161831.768801511.375900.277302.215001.50490HepG2FUBP3
PAMENSG00000145730.164296.408202945.087200.544703.851102.53670HepG2FUS
PAMENSG00000145730.164155.885202409.800500.7861010.712909.44680HepG2G3BP1
PAMENSG00000145730.161979.004302558.47370-0.370503.064602.12680HepG2G3BP2
PAMENSG00000145730.161335.901001687.46520-0.337002.744901.85000HepG2GEMIN5
PAMENSG00000145730.164410.622402774.638600.668605.147603.11920HepG2GTF2F1
PAMENSG00000145730.162192.578703043.35010-0.473003.140201.68380HepG2HNRNPA0
PAMENSG00000145730.161003.021602417.66610-1.2693032.9883031.22610HepG2HNRNPA1
PAMENSG00000145730.164465.145003160.025600.498707.114205.73640HepG2HNRNPA2B1
PAMENSG00000145730.161849.203802689.18480-0.540307.146606.07210HepG2HNRNPC
PAMENSG00000145730.162134.935603116.80940-0.545904.098602.25370HepG2HNRNPD
PAMENSG00000145730.161449.656201925.29750-0.409402.201101.55590HepG2HNRNPF
PAMENSG00000145730.162567.494701451.262000.823009.062407.99660HepG2HNRNPLL
PAMENSG00000145730.161360.572602671.40710-0.9734038.6239036.58650HepG2HNRNPU
PAMENSG00000145730.161083.979901895.87390-0.8065016.0250014.43690HepG2IGF2BP1
PAMENSG00000145730.162416.978203429.29020-0.504703.998702.51530HepG2KHDRBS1
PAMENSG00000145730.162796.928902232.791000.324906.721105.17360HepG2KIF1C
PAMENSG00000145730.16869.980202598.79820-1.5788037.3146035.16130HepG2MAGOH
PAMENSG00000145730.163783.538902056.020000.8798019.9593018.04670HepG2MSI2
PAMENSG00000145730.162500.383501726.544200.534206.828804.94690HepG2NAA15
PAMENSG00000145730.164272.056202381.969600.8427012.8330011.30980HepG2PABPC4
PAMENSG00000145730.161280.296301567.33050-0.291802.714901.49460HepG2PKM
PAMENSG00000145730.162840.218502382.685500.253302.913902.16030HepG2PPIL4
PAMENSG00000145730.161085.911101649.42660-0.6031012.1906010.73540HepG2PRPF4
PAMENSG00000145730.161665.559802931.12130-0.815405.328703.68290HepG2PRPF6
PAMENSG00000145730.161954.523503254.72740-0.7357013.9919012.79240HepG2PUF60
PAMENSG00000145730.162453.549203455.01190-0.4938016.1366014.94650HepG2PUM1
PAMENSG00000145730.164351.215003452.503700.333704.319703.49160HepG2PUM2
PAMENSG00000145730.161577.308802487.90130-0.6575020.0126018.62860HepG2PUS1
PAMENSG00000145730.164663.549502905.553600.6825016.0486014.26210HepG2RBM15
PAMENSG00000145730.164038.415202713.334000.573605.981905.29230HepG2RBM22
PAMENSG00000145730.162806.071702400.858500.224901.890301.32350HepG2RBM25
PAMENSG00000145730.161151.228602377.30290-1.046207.890806.12260HepG2RCC2
PAMENSG00000145730.162060.133102718.40550-0.400004.178403.53830HepG2NELFE
PAMENSG00000145730.162127.581402531.94620-0.251002.612402.01130HepG2RECQL
PAMENSG00000145730.161123.393002073.93430-0.8845015.8066014.43370HepG2RPLP0
PAMENSG00000145730.161424.594602642.60990-0.891407.607306.11060HepG2RPS10
PAMENSG00000145730.161430.968301844.20170-0.366003.592302.90140HepG2RPS19
PAMENSG00000145730.161513.151202700.20640-0.835505.938304.79040HepG2RPS2
PAMENSG00000145730.161900.751503613.82420-0.9270010.793009.26010HepG2RPS3A
PAMENSG00000145730.161664.606702379.01900-0.5152012.9902011.74690HepG2SAFB2
PAMENSG00000145730.162374.544103432.60890-0.531703.220301.54450HepG2SBDS
PAMENSG00000145730.161132.695101993.47630-0.815507.459506.31580HepG2SF3A3
PAMENSG00000145730.165606.708003064.655500.8713036.4285035.15160HepG2SRFBP1
PAMENSG00000145730.162239.478202654.40530-0.245203.216102.71620HepG2SRSF1
PAMENSG00000145730.161060.546501545.62860-0.543404.008202.78040HepG2SRSF3
PAMENSG00000145730.162245.821303213.53930-0.5169012.8029011.58830HepG2SRSF5
PAMENSG00000145730.161212.289801891.52210-0.6418014.6949013.31250HepG2SRSF7
PAMENSG00000145730.163168.892702159.550700.5531015.9373014.80870HepG2SRSF9
PAMENSG00000145730.16465.584802660.92440-2.51480141.03410138.90020HepG2SSB
PAMENSG00000145730.162473.780401696.770800.543804.368902.84730HepG2STAU1
PAMENSG00000145730.163050.965503654.70510-0.260503.172902.51600HepG2SUCLG1
PAMENSG00000145730.162885.488801715.379000.7502014.4067012.38210HepG2SUPT6H
PAMENSG00000145730.162669.976701692.903100.657208.080807.02180HepG2SUPV3L1
PAMENSG00000145730.16886.159702970.58710-1.745106.068504.55230HepG2TBRG4
PAMENSG00000145730.163323.416902192.278300.600109.439307.91130HepG2TIA1
PAMENSG00000145730.161041.263702595.85270-1.3179045.9913044.41220HepG2TIAL1
PAMENSG00000145730.163344.983602618.970200.352906.777805.96290HepG2TRIM56
PAMENSG00000145730.162146.365803179.69000-0.567009.347607.55970HepG2TUFM
PAMENSG00000145730.161262.070602173.32940-0.7841011.7746010.45160HepG2U2AF1
PAMENSG00000145730.162213.533501767.908500.324205.110104.20670HepG2UPF1
PAMENSG00000145730.161263.909701706.84650-0.433407.412006.50920HepG2UTP3
PAMENSG00000145730.161888.141703236.94850-0.777707.441905.64950HepG2XPO5
PAMENSG00000145730.161126.209501666.47250-0.565303.082702.31780HepG2XRN2
PAMENSG00000145730.161933.954401627.797300.248503.336202.61000HepG2ZC3H8
PAMENSG00000145730.163556.496601944.361200.8711020.8380019.68040HepG2ZNF622
PAMENSG00000145730.161968.129802687.78520-0.449602.555501.31460HepG2ZRANB2
PAMENSG00000145730.1692.5454045.435701.026203.011601.72830K562ABCF1
PAMENSG00000145730.1666.6138030.003501.150602.635602.07820K562AGGF1
PAMENSG00000145730.16103.4547039.436401.391305.881104.22380K562CPEB4
PAMENSG00000145730.1611.1349032.67110-1.552902.318901.54240K562FIP1L1
PAMENSG00000145730.1632.8558010.062501.707102.613701.52440K562FKBP4
PAMENSG00000145730.1686.2346020.128902.098907.242104.93570K562GEMIN5
PAMENSG00000145730.16120.9316044.966501.427205.396504.33730K562GRSF1
PAMENSG00000145730.1647.8608011.539102.052204.241403.51860K562HNRNPC
PAMENSG00000145730.1674.7369036.891801.018402.789601.73030K562HNRNPL
PAMENSG00000145730.1637.5881010.349501.860603.013302.06350K562PSIP1
PAMENSG00000145730.16161.4311072.196601.160805.944404.75370K562PUF60
PAMENSG00000145730.16128.8507075.242700.776002.963501.97260K562PUM2
PAMENSG00000145730.1659.6880030.976800.946201.756001.30290K562PUS1
PAMENSG00000145730.1664.7044034.223100.918802.159001.43060K562SF3A3
PAMENSG00000145730.1661.0258027.768501.135902.283501.40910K562SF3B1
PAMENSG00000145730.1641.7155010.592101.977502.863901.89880K562TRIM56
PAMENSG00000145730.1680.4203038.934401.046402.941001.69800K562UTP3
PAMENSG00000145730.1688.8750051.590300.784602.186401.43000K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PAM is not available on ENCORE database.





13 RBPs can affect the splicing of PAM :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPAMENSG00000145730.16chr5+102309819102310140102296861102296933102325975102326105-0.212000.000000.00035excludedHepG2RBM22
SEPAMENSG00000145730.16chr5+1023098191023101401022968611022969331023259751023261050.215000.000740.02109includedHepG2HNRNPK
SEPAMENSG00000145730.16chr5+1023098191023101401022968611022969331023259751023261050.223000.000020.00394includedHepG2QKI
SEPAMENSG00000145730.16chr5+1023098191023101401022968611022969331023259751023261050.408000.000000.00000includedHepG2U2AF2
SEPAMENSG00000145730.16chr5+102353037102353137102345454102345570102355493102355547-0.104000.000000.00000excludedHepG2U2AF2
SEPAMENSG00000145730.16chr5+102360834102361038102355493102355547102363888102363942-0.230000.000010.00034excludedHepG2U2AF2
SEPAMENSG00000145730.16chr5+1023098191023101401022968611022969331023259751023261050.352000.000000.00000includedHepG2PTBP1
SEPAMENSG00000145730.16chr5+1023098191023101401022968611022969331023259751023261050.259000.000020.00188includedHepG2MATR3
SEPAMENSG00000145730.16chr5+102363885102363942102360834102361038102364590102365298-0.112000.001040.06752excludedHepG2HNRNPL
SEPAMENSG00000145730.16chr5+1023098191023101401022968611022969331023259751023261050.398000.000000.00000includedHepG2SRSF1
SEPAMENSG00000145730.16chr5+102237059102237117102202976102203097102249637102249725-0.083000.000310.01212excludedHepG2SF3A3
SEPAMENSG00000145730.16chr5+102360834102361038102355493102355547102363885102363942-0.306000.001620.04458excludedHepG2SF3A3
SEPAMENSG00000145730.16chr5+1022315541022316661022029761022030971022370591022371170.056000.001090.09893includedHepG2SSB
SEPAMENSG00000145730.16chr5+1023608371023610381023554931023555471023638851023639420.298000.000050.00995includedHepG2TAF15
SEPAMENSG00000145730.16chr5+1023098191023101401022968611022969331023259751023261050.224000.000300.02465includedHepG2SRSF9
SEPAMENSG00000145730.16chr5+1023098191023101401022968611022969331023259751023261050.253000.000030.07544includedHepG2DDX52

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PAM is not avaliable on ENCORE database.