IDUA

General Information

Gene Name       : IDUA
Gene ID             : ENSG00000127415.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: IDUA)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878IDUAENSG00000127415.120.000.160.08ENCSR000AEF
HepG2IDUAENSG00000127415.120.620.060.34ENCSR985KAT
K562IDUAENSG00000127415.120.880.200.54ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for IDUA is not avaliable on ENCORE database.



Proteins bound to RNA
  • IDUA RNA is bound by 14 proteins.  







eCLIP assay for IDUA is not avaliable on ENCORE database.





14 proteins are bound to IDUA RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr4994649994711+5'-UTR,CDS,intron-Proximal3.277896.25514K562RBFOX2
chr4994662994748+5'-UTR,CDS,intron-Proximal4.3929610.09214K562DDX24
chr4994424994512+5'-UTR,CDS,intron-Proximal4.161083.62765K562SRSF1
chr4994735994845+CDS,intron-Proximal3.8105611.50829K562RBFOX2
chr4994717994819+CDS,intron-Proximal4.234834.53461K562SRSF1
chr4994748994852+CDS,intron-Proximal4.2177713.89500K562DDX24
chr4997027997155+CDS,intron-Proximal4.4305319.02275K562PRPF8
chr4995222995322+CDS,intron-Proximal4.001993.15171K562SRSF1
chr4994763994841+CDS,intron-Proximal3.397185.65306K562ZNF622
chr4994762994852+CDS,intron-Proximal3.062023.20331K562CSTF2T
chr4995114995138+intron-Distal3.765813.25414K562RBFOX2
chr4994936995076+intron-Distal5.2812118.69631K562DDX24
chr4994972995057+intron-Distal4.349225.08521K562GEMIN5
chr4994907994974+intron-Distal5.3936711.28741K562BUD13
chr4994971995069+intron-Distal4.6779619.84745K562RBFOX2
chr4994921995024+intron-Distal4.098075.75237K562PCBP1
chr4994880995067+intron-Distal3.600256.02234K562UCHL5
chr4994946995075+intron-Distal4.3233012.33634K562PRPF8
chr4994926995022+intron-Distal3.201323.29548K562XRN2
chr4997014997098+intron-Proximal5.291936.89521K562AKAP8L
chr4997027997096+intron-Proximal3.822705.29296K562DROSHA
chr4997009997123+intron-Proximal6.6407728.52410K562DDX24
chr4997002997113+intron-Proximal4.4265519.95603K562BUD13
chr4997024997081+intron-Proximal3.165963.43327K562XRCC6
chr4997030997094+intron-Proximal4.439284.07072K562UCHL5
chr4997008997092+intron-Proximal4.700303.71567HepG2RBFOX2
chr4994784994857+intron-Proximal4.6276811.64021K562BUD13
chr4997009997132+intron-Proximal4.1790516.92117K562RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for IDUA is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for IDUA is not available on ENCORE database.

  • 95 RBPs can affect the levels of IDUA.  








The Knockdown/knockout RNA-Seq assay for IDUA is not available on ENCORE database.





95 RBPs can affect the gene expression of IDUA :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
IDUAENSG00000127415.890.4345020.286402.156306.855806.06030HepG2AKAP1
IDUAENSG00000127415.8111.2063052.544301.081503.649202.46260HepG2AKAP8
IDUAENSG00000127415.859.2811013.922102.090103.627502.55560HepG2BCCIP
IDUAENSG00000127415.8112.2939037.002201.601506.790405.90070HepG2BOP1
IDUAENSG00000127415.841.5129012.220601.764103.296201.81730HepG2DDX52
IDUAENSG00000127415.850.3761016.706401.592203.162402.50620HepG2DDX6
IDUAENSG00000127415.833.7959011.177301.596202.921502.25450HepG2DNAJC2
IDUAENSG00000127415.846.7877014.574301.682602.787001.86400HepG2EEF2
IDUAENSG00000127415.889.8074016.039702.485109.576408.51280HepG2EIF2S1
IDUAENSG00000127415.859.0429017.715801.736604.302003.50870HepG2EIF4A3
IDUAENSG00000127415.866.5451017.267801.946104.688303.80720HepG2EIF4B
IDUAENSG00000127415.8106.2269040.847001.378705.448804.65320HepG2ETF1
IDUAENSG00000127415.833.1663010.578001.648502.689101.54100HepG2FAM120A
IDUAENSG00000127415.8112.3459036.407601.625504.888703.89040HepG2FIP1L1
IDUAENSG00000127415.840.0157015.562401.362402.371001.33270HepG2FUS
IDUAENSG00000127415.845.3452017.904601.340502.299601.66620HepG2FXR1
IDUAENSG00000127415.864.7632016.593301.964505.629804.69430HepG2G3BP1
IDUAENSG00000127415.858.0390012.659802.196702.837802.13630HepG2HNRNPC
IDUAENSG00000127415.874.3035016.839102.141504.107303.27060HepG2HNRNPK
IDUAENSG00000127415.866.3782025.120001.401803.760002.66870HepG2HNRNPM
IDUAENSG00000127415.843.7214012.576001.797604.083503.35830HepG2HNRNPU
IDUAENSG00000127415.8131.0603057.150201.197304.506703.43680HepG2LARP4
IDUAENSG00000127415.845.9569018.006301.351701.984301.44530HepG2MATR3
IDUAENSG00000127415.864.4935029.466401.130002.527301.75280HepG2MSI2
IDUAENSG00000127415.8111.3900018.426502.5957011.2747010.03880HepG2NCBP2
IDUAENSG00000127415.884.2043020.167002.061808.253206.95840HepG2NOL12
IDUAENSG00000127415.89.3542032.58280-1.800402.280701.59930HepG2NSUN2
IDUAENSG00000127415.852.9440016.391801.691403.916003.06800HepG2PABPC4
IDUAENSG00000127415.881.8170016.342802.323608.960308.08880HepG2PTBP1
IDUAENSG00000127415.873.6486020.429601.849906.645805.80980HepG2PUM1
IDUAENSG00000127415.873.2329017.700102.048606.462705.56450HepG2QKI
IDUAENSG00000127415.855.6043018.052701.622902.867101.85840HepG2RBM27
IDUAENSG00000127415.8100.4348018.188102.4651010.646609.71320HepG2NELFE
IDUAENSG00000127415.879.7660041.698300.935702.546801.88720HepG2RPLP0
IDUAENSG00000127415.860.5269011.512302.394305.989305.12550HepG2RPS19
IDUAENSG00000127415.877.7092016.643102.223106.319105.14030HepG2RPS2
IDUAENSG00000127415.864.0382017.015301.912005.352004.57530HepG2SF3B4
IDUAENSG00000127415.832.8378013.057901.330302.121001.54650HepG2SMN1
IDUAENSG00000127415.840.0893014.548001.462302.866601.89250HepG2SMNDC1
IDUAENSG00000127415.867.8712019.000901.836602.534701.93070HepG2SRSF5
IDUAENSG00000127415.871.8895027.086601.408103.868802.54610HepG2STIP1
IDUAENSG00000127415.8108.9938021.612702.3342012.1851011.03850HepG2SUCLG1
IDUAENSG00000127415.880.5146035.825201.168203.145602.37780HepG2TARDBP
IDUAENSG00000127415.847.8287012.214101.969204.583603.97410HepG2TIAL1
IDUAENSG00000127415.851.0079012.329602.048505.081304.36390HepG2TRIM56
IDUAENSG00000127415.8141.6137084.195100.750102.555401.38750K562ABCF1
IDUAENSG00000127415.8141.5192060.484301.226304.219402.07320K562ADAR
IDUAENSG00000127415.8223.38730145.639500.617003.356902.74310K562AGGF1
IDUAENSG00000127415.8250.75120160.061400.647503.681502.50840K562AKAP8
IDUAENSG00000127415.8251.53110151.550800.730802.608901.97350K562AKAP8L
IDUAENSG00000127415.8242.78000159.025200.610303.740502.66520K562ATP5C1
IDUAENSG00000127415.8116.0215042.986601.432306.122304.67480K562BCLAF1
IDUAENSG00000127415.8127.4521034.978401.865308.723007.12650K562BOP1
IDUAENSG00000127415.8202.4981059.240001.773205.524903.91110K562CCAR1
IDUAENSG00000127415.8268.78940174.026700.627103.387902.06530K562CCDC124
IDUAENSG00000127415.8210.18600117.692200.836504.525503.08740K562CPEB4
IDUAENSG00000127415.8137.8823037.195701.8901010.474108.93460K562CPSF6
IDUAENSG00000127415.871.9269032.611801.141002.838901.76900K562CSTF2
IDUAENSG00000127415.8229.08510128.022100.839405.413103.67910K562DDX21
IDUAENSG00000127415.8240.67880121.762600.982903.956003.19630K562DDX47
IDUAENSG00000127415.8178.5968066.335101.428804.503202.73780K562DHX30
IDUAENSG00000127415.8127.9418063.696501.006104.057402.40850K562DNAJC21
IDUAENSG00000127415.8182.7276072.735701.328908.731307.56270K562EIF2S2
IDUAENSG00000127415.8134.7564076.325900.820003.685302.31890K562EIF4B
IDUAENSG00000127415.8197.91270133.581400.567002.245401.39620K562EIF4G2
IDUAENSG00000127415.8128.7289078.082500.721202.585701.36450K562EXOSC5
IDUAENSG00000127415.8109.3202060.520900.853002.784201.93250K562FIP1L1
IDUAENSG00000127415.880.2435037.838801.084402.889702.01560K562FMR1
IDUAENSG00000127415.8113.4831032.068701.823108.238806.57140K562FTO
IDUAENSG00000127415.838.1491088.14220-1.208204.044203.33350K562FXR1
IDUAENSG00000127415.8200.62150106.316600.916005.506603.92290K562GLRX3
IDUAENSG00000127415.8140.1262035.515701.9801010.793809.20410K562GPKOW
IDUAENSG00000127415.8207.8727096.911501.100905.831504.72930K562GRSF1
IDUAENSG00000127415.8166.60770102.296600.703603.073001.94030K562HNRNPA1
IDUAENSG00000127415.8172.5656096.178700.843302.525601.37670K562HNRNPA2B1
IDUAENSG00000127415.8195.3220065.337801.5798010.100209.01560K562HNRNPC
IDUAENSG00000127415.8103.2921058.389600.822802.347401.31010K562HNRNPF
IDUAENSG00000127415.8210.78300113.295800.895605.537904.25970K562HNRNPU
IDUAENSG00000127415.874.0720025.641501.530302.260401.36030K562IGF2BP2
IDUAENSG00000127415.8140.4458059.784801.232105.684903.56970K562KHDRBS1
IDUAENSG00000127415.865.1663030.318401.103802.214401.38990K562KRR1
IDUAENSG00000127415.824.4328063.39880-1.375602.822101.41940K562LARP7
IDUAENSG00000127415.854.8601026.849901.030702.320201.48160K562MATR3
IDUAENSG00000127415.8134.1542034.666001.9522010.352008.58160K562METAP2
IDUAENSG00000127415.8219.24730111.779100.971806.567905.37010K562MTPAP
IDUAENSG00000127415.8246.63450124.190500.989707.518106.37210K562NSUN2
IDUAENSG00000127415.8199.8680090.212501.147505.023603.33070K562PABPC1
IDUAENSG00000127415.8229.45320137.260500.741204.048102.34410K562PNPT1
IDUAENSG00000127415.8114.1528058.594100.962002.892701.96530K562PSIP1
IDUAENSG00000127415.8301.34390151.889400.988307.335605.74590K562PUM2
IDUAENSG00000127415.8228.08970150.251700.602102.647102.11240K562PUS1
IDUAENSG00000127415.8165.4736063.226401.387906.900703.75600K562RBFOX2
IDUAENSG00000127415.868.0328026.367901.367304.039802.68550K562NELFE
IDUAENSG00000127415.872.2933033.766101.098202.498901.57630K562SF3B1
IDUAENSG00000127415.8142.3063065.218001.125605.078603.33180K562SLBP
IDUAENSG00000127415.896.0985050.726700.921702.624301.63380K562SRFBP1
IDUAENSG00000127415.8141.3235049.025401.527306.892305.11110K562SRSF4
IDUAENSG00000127415.871.1807024.223501.555005.037203.54040K562SRSF5
IDUAENSG00000127415.8220.52490127.161300.794203.601601.88130K562SUCLG1
IDUAENSG00000127415.831.9971076.41530-1.255903.448502.53300K562SYNCRIP
IDUAENSG00000127415.8105.7935025.938002.028005.426004.41850K562TARDBP
IDUAENSG00000127415.869.5388025.022501.474504.312503.25710K562TIA1
IDUAENSG00000127415.8101.5304056.350800.849302.316801.46600K562TIAL1
IDUAENSG00000127415.870.0177024.576301.510404.359402.93510K562TRA2A
IDUAENSG00000127415.8179.7664059.929501.584709.772307.72050K562TRIM56
IDUAENSG00000127415.8295.56030131.682301.1663010.990909.67630K562UPF1
IDUAENSG00000127415.8171.1455093.835600.866903.925102.48520K562UTP3
IDUAENSG00000127415.8253.16720112.675601.167809.189307.55510K562WDR3
IDUAENSG00000127415.897.7156040.969101.254002.557401.40940K562XRN2
IDUAENSG00000127415.8237.99260134.998700.817902.632301.79470K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for IDUA is not available on ENCORE database.





1 RBPs can affect the splicing of IDUA :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEIDUAENSG00000127415.8chr4+993740993852981596981737994399994485-0.350000.002930.07070excludedK562AKAP8L

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for IDUA is not avaliable on ENCORE database.