GSS

General Information

Gene Name       : GSS
Gene ID             : ENSG00000100983.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: GSS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GSSENSG00000100983.1031.4546.9339.19ENCSR000AEF
HepG2GSSENSG00000100983.1078.9962.9870.98ENCSR985KAT
K562GSSENSG00000100983.1073.3372.1972.76ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GSS is not avaliable on ENCORE database.



Proteins bound to RNA
  • GSS RNA is bound by 14 proteins.  







eCLIP assay for GSS is not avaliable on ENCORE database.





14 proteins are bound to GSS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr203351629733516394-3'-UTR,intron-Distal4.053973.95192HepG2UPF1
chr203351643833516474-3'-UTR,intron-Distal,intron-Proximal3.621505.10442K562YBX3
chr203351641133516468-3'-UTR,intron-Distal,intron-Proximal3.485564.08867HepG2LARP4
chr203353376733533802-5'-UTR,CDS,intron-Distal3.538305.15749K562YBX3
chr203353371633533760-5'-UTR,CDS,intron-Distal,intron-Proximal3.485256.35344K562PRPF8
chr203354352933543576-5'-UTR,intron-Distal3.877985.63105K562DDX3X
chr203353038933530500-5'-UTR,CDS,intron-Distal,intron-Proximal3.035989.06842HepG2PRPF8
chr203353072333530734-5'-UTR,intron-Distal,intron-Proximal6.7324022.27579K562AQR
chr203353046033530505-5'-UTR,intron-Distal,intron-Proximal6.4898516.98862K562AQR
chr203353388833533901-5'-UTR,CDS,intron-Distal3.777413.30425K562LIN28B
chr203353038333530427-5'-UTR,CDS,intron-Distal4.691297.41523K562YBX3
chr203353046133530512-5'-UTR,intron-Distal,intron-Proximal4.163765.56912HepG2AQR
chr203353061733530674-5'-UTR,intron-Distal,intron-Proximal4.2470313.77836K562PRPF8
chr203353961833539657-5'-UTR,CDS,intron-Distal,intron-Proximal4.433505.11007HepG2GRWD1
chr203353036833530461-5'-UTR,CDS,intron-Distal,intron-Proximal4.1824910.42788HepG2AQR
chr203353061933530678-5'-UTR,intron-Distal,intron-Proximal3.335204.63145K562BUD13
chr203353045933530502-5'-UTR,intron-Distal,intron-Proximal3.996163.18234K562BUD13
chr203353036533530457-5'-UTR,CDS,intron-Distal,intron-Proximal6.0085162.36777K562AQR
chr203353957833539664-5'-UTR,CDS,intron-Distal,intron-Proximal3.208156.60215K562DDX3X
chr203353062433530668-5'-UTR,intron-Distal,intron-Proximal6.0222818.99614K562AQR
chr203353073433530804-5'-UTR,CDS,intron-Distal4.0248211.79269K562YBX3
chr203353068433530741-5'-UTR,CDS,intron-Distal,intron-Proximal4.545297.56654HepG2PRPF8
chr203353037333530479-5'-UTR,CDS,intron-Distal,intron-Proximal3.1237915.83756K562PRPF8
chr203353068333530723-5'-UTR,intron-Distal,intron-Proximal6.3893234.42425K562AQR
chr203353044833530499-5'-UTR,intron-Distal,intron-Proximal4.139165.44908K562SF3B4
chr203353371133533795-5'-UTR,CDS,intron-Distal,intron-Proximal4.7567813.14214HepG2PRPF8
chr203351988033519935-CDS,intron-Distal3.262715.33987HepG2GRWD1
chr203353029133530351-CDS,intron-Distal3.7247012.86652K562YBX3
chr203352339333523411-CDS,intron-Distal3.302113.31745K562ZNF622
chr203352954233529566-CDS,intron-Distal4.437704.38106HepG2PPIG
chr203352474833524778-CDS,intron-Distal3.053983.24816K562YBX3
chr203353957933539655-CDS,intron-Distal4.318787.52225K562UCHL5
chr203353949433539541-CDS,intron-Distal,intron-Proximal3.233473.40738HepG2PRPF8
chr203353952333539564-CDS,intron-Distal,intron-Proximal4.516435.87734K562LIN28B
chr203351987433519935-CDS,intron-Distal3.243779.44988HepG2PPIG
chr203353790633537989-intron-Distal4.392644.20763HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GSS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GSS is not available on ENCORE database.

  • 96 RBPs can affect the levels of GSS.  








The Knockdown/knockout RNA-Seq assay for GSS is not available on ENCORE database.





96 RBPs can affect the gene expression of GSS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GSSENSG00000100983.51576.201201171.875900.427503.015802.03030HepG2ABCF1
GSSENSG00000100983.51552.451801038.184900.5804012.4567011.36580HepG2ACO1
GSSENSG00000100983.52737.463601387.179600.9806013.5825012.49620HepG2AKAP1
GSSENSG00000100983.51577.328601147.743900.458603.792302.87730HepG2ASCC1
GSSENSG00000100983.52042.773001284.896300.668805.871104.42630HepG2CCAR1
GSSENSG00000100983.51489.845601090.445700.450103.757702.86590HepG2CIRBP
GSSENSG00000100983.51320.821901556.51120-0.236902.833802.08430HepG2DAZAP1
GSSENSG00000100983.51124.82810960.124600.228302.285001.52230HepG2DDX19B
GSSENSG00000100983.51903.56410919.133201.0503021.4372019.78440HepG2DDX21
GSSENSG00000100983.5542.169701009.77310-0.897205.675704.29130HepG2DDX59
GSSENSG00000100983.51273.30000897.522100.504504.331203.20350HepG2EEF2
GSSENSG00000100983.51805.644601212.539100.574405.038504.17980HepG2EIF4A3
GSSENSG00000100983.51037.035201471.00490-0.504304.511803.48800HepG2EIF4G2
GSSENSG00000100983.51263.000401014.400000.316102.561801.75850HepG2EWSR1
GSSENSG00000100983.5541.69090890.73930-0.717502.717001.70980HepG2FTO
GSSENSG00000100983.51780.443101223.626600.541005.151404.22830HepG2FXR1
GSSENSG00000100983.5761.42220520.697400.548203.026401.85990HepG2GRSF1
GSSENSG00000100983.51164.82850915.975700.346602.675702.03860HepG2HNRNPA1
GSSENSG00000100983.51278.663701018.810200.327702.397901.74810HepG2HNRNPC
GSSENSG00000100983.51213.299801592.94490-0.392805.547204.57430HepG2HNRNPF
GSSENSG00000100983.51238.260001417.86070-0.195402.046701.45610HepG2HNRNPL
GSSENSG00000100983.51572.306401230.869000.353102.172201.61000HepG2MATR3
GSSENSG00000100983.51434.06270957.779800.582207.469806.20150HepG2MSI2
GSSENSG00000100983.5705.39400981.05930-0.475902.251901.38260HepG2MTPAP
GSSENSG00000100983.5964.412701543.43370-0.6784011.9520010.41490HepG2NOL12
GSSENSG00000100983.5599.74620852.95480-0.508104.021803.12410HepG2NSUN2
GSSENSG00000100983.51366.911501151.638700.247102.523501.93700HepG2PCBP1
GSSENSG00000100983.51553.768801171.876700.406906.282005.52310HepG2PTBP1
GSSENSG00000100983.5938.849801473.34430-0.650108.828807.84460HepG2PUF60
GSSENSG00000100983.51961.433701564.022000.326505.951405.14880HepG2PUM1
GSSENSG00000100983.51619.573801057.443400.6149014.1191012.91610HepG2PUS1
GSSENSG00000100983.51008.136501269.08350-0.332103.040502.39100HepG2QKI
GSSENSG00000100983.5534.67680864.34490-0.692903.629502.82440HepG2RAVER1
GSSENSG00000100983.5923.800301151.80800-0.318202.420701.78670HepG2RBM25
GSSENSG00000100983.51268.71670922.295200.460003.227202.08130HepG2RCC2
GSSENSG00000100983.51544.718901304.152000.244102.471401.95510HepG2NELFE
GSSENSG00000100983.5977.28340708.951000.463003.744003.03960HepG2RPS19
GSSENSG00000100983.51369.556101047.461400.386702.841102.03070HepG2RPS2
GSSENSG00000100983.5761.35090564.887700.430502.194201.48120HepG2RPS3A
GSSENSG00000100983.51435.491901039.399500.465701.980601.40820HepG2SF3A3
GSSENSG00000100983.5597.87970952.15030-0.671306.839405.77190HepG2SF3B1
GSSENSG00000100983.51037.841901412.71150-0.444907.642206.56490HepG2SLBP
GSSENSG00000100983.51358.611401051.140900.370103.854103.11590HepG2SMN1
GSSENSG00000100983.5758.018501059.43310-0.483002.467301.73040HepG2SNRNP70
GSSENSG00000100983.51756.489502065.45850-0.233802.954902.44260HepG2SRFBP1
GSSENSG00000100983.52149.887201273.447000.7554021.9891020.92780HepG2SRSF1
GSSENSG00000100983.5748.938401024.50830-0.452002.636201.66220HepG2SRSF3
GSSENSG00000100983.51178.139701454.71520-0.304203.513202.82350HepG2SRSF5
GSSENSG00000100983.51112.078701564.99570-0.492908.436407.33520HepG2SRSF7
GSSENSG00000100983.5634.220401036.04300-0.7080013.2778012.22980HepG2SRSF9
GSSENSG00000100983.5695.98410924.89800-0.410202.570701.33400HepG2SSRP1
GSSENSG00000100983.52056.030601654.409900.313404.928904.13990HepG2SUCLG1
GSSENSG00000100983.51600.99220983.585200.7027012.3499011.42520HepG2TIAL1
GSSENSG00000100983.5586.208301012.30150-0.788208.890807.75800HepG2U2AF1
GSSENSG00000100983.5311.30710760.85560-1.289304.298303.05650HepG2U2AF2
GSSENSG00000100983.51159.71050921.790600.331203.862203.05740HepG2UPF1
GSSENSG00000100983.51566.48130889.949300.8156021.4565020.02090HepG2UTP3
GSSENSG00000100983.51550.92130950.692000.706005.599904.12390HepG2XRCC6
GSSENSG00000100983.51400.666701013.790100.466308.951108.11150HepG2ZNF622
GSSENSG00000100983.52615.517302312.892800.177301.843201.36100K562AGGF1
GSSENSG00000100983.5964.388102599.05930-1.4303037.4824035.52840K562AQR
GSSENSG00000100983.5551.39920964.48330-0.806704.788003.62860K562BOP1
GSSENSG00000100983.5923.817001223.06500-0.404802.772301.35660K562BUD13
GSSENSG00000100983.51379.624001909.45160-0.468903.745202.02190K562CKAP4
GSSENSG00000100983.51110.869701846.38410-0.733004.766703.32250K562CNOT7
GSSENSG00000100983.5695.514701025.55630-0.560304.937003.89570K562CPSF6
GSSENSG00000100983.52840.136003836.08710-0.433707.191405.64270K562CELF1
GSSENSG00000100983.51070.239601331.73840-0.315402.658201.63670K562DDX3X
GSSENSG00000100983.5827.100101141.24100-0.464503.019401.63170K562DHX30
GSSENSG00000100983.5759.960401162.16510-0.612803.203301.30780K562DNAJC2
GSSENSG00000100983.5948.416701305.02720-0.460504.268903.11850K562EFTUD2
GSSENSG00000100983.5954.285101397.10720-0.550004.368503.03390K562EIF3D
GSSENSG00000100983.5829.603701391.31840-0.7460010.650509.01850K562EIF4A3
GSSENSG00000100983.52528.892003119.48040-0.302804.520203.33210K562EIF4G2
GSSENSG00000100983.5620.561001043.41380-0.749707.698806.22910K562FMR1
GSSENSG00000100983.5505.01870884.35890-0.808308.434706.74290K562FTO
GSSENSG00000100983.5608.393201104.41050-0.860208.093006.75800K562G3BP2
GSSENSG00000100983.5949.632901308.39580-0.462403.791902.08310K562GEMIN5
GSSENSG00000100983.5553.50930979.18090-0.8230010.682909.10530K562GPKOW
GSSENSG00000100983.51542.862302028.97850-0.395104.420903.06790K562HNRNPA1
GSSENSG00000100983.5642.160901469.05080-1.1939026.2318024.47420K562HNRNPC
GSSENSG00000100983.51002.489801312.04600-0.388203.431702.15030K562HNRNPF
GSSENSG00000100983.51348.228501038.269000.376802.527601.64000K562HNRNPM
GSSENSG00000100983.51886.486902247.02150-0.252302.555001.69530K562HNRNPU
GSSENSG00000100983.52081.756001711.235900.282702.139901.43700K562HSPD1
GSSENSG00000100983.5736.822101029.54760-0.482603.091101.52140K562KHDRBS1
GSSENSG00000100983.5465.07720836.02750-0.846107.069305.50790K562KRR1
GSSENSG00000100983.51090.817901702.25730-0.642009.345407.74110K562MAGOH
GSSENSG00000100983.5655.51050955.77840-0.544105.494404.23400K562METAP2
GSSENSG00000100983.52526.463103324.98210-0.396204.239402.84400K562MSI2
GSSENSG00000100983.51286.835901697.85120-0.399906.256605.08260K562MTPAP
GSSENSG00000100983.52577.052703412.35860-0.405004.446902.52980K562NOL12
GSSENSG00000100983.51517.869801886.38790-0.313605.599304.59330K562NSUN2
GSSENSG00000100983.5997.246801514.45890-0.602807.366405.74110K562PCBP2
GSSENSG00000100983.51214.524401767.46820-0.541305.058303.93340K562PCBP3
GSSENSG00000100983.51002.601201355.76000-0.435404.664403.62360K562POLR2G
GSSENSG00000100983.5899.455501269.94640-0.497604.529603.57040K562PRPF8
GSSENSG00000100983.51762.716603403.52910-0.9492020.0351017.75220K562PUF60
GSSENSG00000100983.52776.228403620.60870-0.383105.691204.11640K562PUM1
GSSENSG00000100983.52721.085403547.04950-0.382406.750705.23290K562PUM2
GSSENSG00000100983.5704.425601053.66360-0.580903.042301.54760K562RAVER1
GSSENSG00000100983.51641.999002220.09960-0.435205.270603.05860K562RBM17
GSSENSG00000100983.51166.960901585.51000-0.442204.329703.24980K562RBM22
GSSENSG00000100983.5804.264601047.16700-0.380703.403501.91360K562RBM25
GSSENSG00000100983.51257.260901668.58560-0.408303.441602.20250K562NELFE
GSSENSG00000100983.51358.394401861.49840-0.454607.296206.02250K562SF3A3
GSSENSG00000100983.5491.73490931.13730-0.921109.749707.84040K562SF3B1
GSSENSG00000100983.5705.022401148.04110-0.7034010.824109.07630K562SF3B4
GSSENSG00000100983.5746.484401123.08290-0.589304.002502.46270K562SLBP
GSSENSG00000100983.51654.824601907.15560-0.204702.377801.50180K562SRPK2
GSSENSG00000100983.5739.634201229.34690-0.733007.670805.92080K562SUPV3L1
GSSENSG00000100983.5576.718301070.13730-0.8919010.017907.72780K562U2AF1
GSSENSG00000100983.5415.750801105.34820-1.4107034.6639031.93670K562U2AF2
GSSENSG00000100983.51007.138001301.23020-0.369602.809601.78150K562UCHL5
GSSENSG00000100983.51393.667002000.18320-0.5212011.174809.85140K562UPF1
GSSENSG00000100983.51188.091701984.16080-0.739908.783706.75640K562UTP3
GSSENSG00000100983.51506.060401779.81300-0.240902.930602.05950K562WDR43
GSSENSG00000100983.52040.264402927.86730-0.521106.889705.43080K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GSS is not available on ENCORE database.





26 RBPs can affect the splicing of GSS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGSSENSG00000100983.5chr20-3351683733517040335166303351675433517203335173930.053000.000030.02392includedK562TAF15
SEGSSENSG00000100983.5chr20-335294993352963233524745335248263353029033530809-0.080000.002400.07083excludedK562PRPF8
SEGSSENSG00000100983.5chr20-335302903353043033524745335248263353073333530809-0.101000.000070.00198excludedHepG2U2AF1
SEGSSENSG00000100983.5chr20-335168373351704033516630335167543351720333517393-0.056000.001140.08112excludedHepG2TBRG4
SEGSSENSG00000100983.5chr20-335295153352963233524745335248263353029033530809-0.137000.000000.00008excludedHepG2U2AF2
SEGSSENSG00000100983.5chr20-335302903353043033524745335248263353073333530809-0.078000.000010.00033excludedK562AQR
SEGSSENSG00000100983.5chr20-335302903353048433529515335296323353073333530809-0.101000.002730.05129excludedK562U2AF1
SEGSSENSG00000100983.5chr20-335233783352344533519741335199363352456533524643-0.060000.000930.02131excludedK562U2AF1
SEGSSENSG00000100983.5chr20-335172033351739333516630335167543351913833519220-0.060000.000290.01415excludedK562TARDBP
SEGSSENSG00000100983.5chr20-335172033351739333516630335167543351913833519220-0.063000.000170.01018excludedK562PTBP1
SEGSSENSG00000100983.5chr20-335302903353048433529499335296323353073333530809-0.082000.003790.05588excludedK562HNRNPC
A3SSGSSENSG00000100983.5chr20-3353029033530484335302903353043033530733335308090.057000.000080.01838longerHepG2TIAL1
A3SSGSSENSG00000100983.5chr20-3351720333517430335172033351739333519138335192200.053000.000000.00001longerK562AQR
A3SSGSSENSG00000100983.5chr20-3351974133519977335197413351993633523378335234670.054000.000000.00001longerK562AQR
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.144000.002090.06014includedK562SF3B1
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.082000.004780.08557includedHepG2UCHL5
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.063000.002840.07729includedHepG2TIA1
RIGSSENSG00000100983.5chr20-335302903353080933530290335304303353073333530809-0.098000.000000.00024excludedK562SRSF1
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.073000.000630.04724includedK562PHF6
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.070000.000330.06071includedHepG2NOL12
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.082000.001310.03211includedHepG2FTO
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.133000.000000.00002includedHepG2QKI
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.106000.000000.00004includedHepG2TAF15
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.110000.000000.00000includedHepG2TIAL1
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.053000.007570.04927includedHepG2SF3B4
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.100000.000070.00231includedHepG2SRSF9
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.150000.000000.00000includedHepG2HNRNPK
RIGSSENSG00000100983.5chr20-3353029033530809335302903353043033530733335308090.108000.000320.00478includedK562EFTUD2
RIGSSENSG00000100983.5chr20-335302903353080933530290335304303353073333530809-0.203000.000010.00197excludedK562FXR2
MXEGSSENSG00000100983.5chr20-33529515335296323353029033530430335247453352482633530733335308090.124000.010360.089521includedK562DROSHA
MXEGSSENSG00000100983.5chr20-33529515335296323353029033530430335247453352482633530733335308090.106000.004030.071841includedHepG2DDX55
MXEGSSENSG00000100983.5chr20-33529515335296323353029033530484335247453352482633530733335308090.113000.000000.000011includedHepG2U2AF2
MXEGSSENSG00000100983.5chr20-33523378335234453352456533524643335197413351993633524745335248260.152000.002950.019881includedHepG2U2AF2
MXEGSSENSG00000100983.5chr20-33529515335296323353029033530430335247453352482633530733335308090.098000.005210.088871includedK562SBDS

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GSS is not avaliable on ENCORE database.