VKORC1L1

General Information

Gene Name       : VKORC1L1
Gene ID             : ENSG00000196715.6
Essential Gene : No

Functions

Localization

Domains (AlphaFold: VKORC1L1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878VKORC1L1ENSG00000196715.611.4010.6511.03ENCSR000AEF
HepG2VKORC1L1ENSG00000196715.612.7120.4016.55ENCSR985KAT
K562VKORC1L1ENSG00000196715.622.8124.5823.70ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for VKORC1L1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • VKORC1L1 RNA is bound by 38 proteins.  







eCLIP assay for VKORC1L1 is not avaliable on ENCORE database.





38 proteins are bound to VKORC1L1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr76541956565419615+3'-UTR3.681586.30288K562PUM2
chr76542341865423512+3'-UTR6.1305017.60344K562PUM2
chr76541972865419849+3'-UTR4.5793550.49443K562PUM2
chr76542166265421748+3'-UTR4.551633.47885K562LIN28B
chr76541963165419738+3'-UTR3.442314.46783HepG2FUBP3
chr76542166765421755+3'-UTR4.207474.01886HepG2LIN28B
chr76541943165419481+3'-UTR3.760626.10049K562TIA1
chr76542152265421582+3'-UTR3.577716.67890K562PUM2
chr76541961565419682+3'-UTR4.1259013.98309K562PUM2
chr76541938165419431+3'-UTR,CDS4.119868.41305K562TIA1
chr76533833365338389+5'-UTR,CDS4.899374.46189K562GTF2F1
chr76533832465338406+5'-UTR,CDS3.905549.22172HepG2CSTF2T
chr76533827565338339+5'-UTR3.919673.33043HepG2NCBP2
chr76533827965338325+5'-UTR3.366893.10855K562FTO
chr76533828265338367+5'-UTR,CDS4.4170411.59134HepG2FAM120A
chr76533827565338351+5'-UTR4.434273.67093HepG2FTO
chr76533828465338315+5'-UTR3.486393.77708K562GTF2F1
chr76533827865338355+5'-UTR3.958554.39367K562PUM1
chr76533826765338334+5'-UTR4.5012719.27291HepG2DDX3X
chr76533826865338373+5'-UTR,CDS3.357525.18500K562GEMIN5
chr76533834065338399+5'-UTR,CDS3.678364.03920K562FTO
chr76533846165338551+CDS4.116956.85787HepG2CSTF2T
chr76533842765338506+CDS3.805237.30480HepG2DDX3X
chr76533850665338553+CDS,intron-Proximal4.7510511.73310HepG2DDX3X
chr76534469765344743+intron-Distal4.302167.03179HepG2PTBP1
chr76533886465338919+intron-Distal5.4829910.48231HepG2CSTF2T
chr76537096165371025+intron-Distal3.387055.81842K562PTBP1
chr76533868765338761+intron-Distal3.8872711.36412K562AKAP8L
chr76536665965366755+intron-Distal3.047713.56066K562SAFB
chr76533883465338905+intron-Distal4.725586.48468K562FASTKD2
chr76533893565338989+intron-Distal4.569965.19780K562NONO
chr76533867165338750+intron-Distal6.6832215.62361HepG2FAM120A
chr76538989565390029+intron-Distal4.983895.72657HepG2MATR3
chr76537469765374756+intron-Distal4.139653.46495K562TARDBP
chr76536666665366763+intron-Distal3.519667.14447K562SAFB2
chr76533983965339935+intron-Distal3.953843.77350HepG2CSTF2
chr76533869865338766+intron-Distal4.545853.58113K562EWSR1
chr76534471765344742+intron-Distal4.139607.33269K562PTBP1
chr76536957865369646+intron-Distal3.384094.88138K562KHDRBS1
chr76533881165338979+intron-Distal4.1754411.61371HepG2GTF2F1
chr76534484865344908+intron-Distal5.422536.95895K562PTBP1
chr76537939165379528+intron-Distal4.983206.79054HepG2PCBP2
chr76533887765338986+intron-Distal6.3240816.07151K562GTF2F1
chr76533982565339963+intron-Distal3.095433.31457K562KHDRBS1
chr76537522765375289+intron-Distal3.399103.94088HepG2QKI
chr76539551665395563+intron-Distal4.008643.07980HepG2HNRNPM
chr76533868565338754+intron-Distal3.660726.59225HepG2CSTF2T
chr76534474365344795+intron-Distal3.887147.02840HepG2PTBP1
chr76538450765384562+intron-Distal4.213444.31720HepG2MATR3
chr76536661165366710+intron-Distal3.602614.67702K562GTF2F1
chr76533866165338757+intron-Distal4.239699.46556HepG2PRPF4
chr76540549365405612+intron-Distal4.556216.68667K562SAFB2
chr76533880365338897+intron-Distal4.2957110.15746HepG2PRPF4
chr76533901065339049+intron-Distal4.116313.69819HepG2CSTF2T
chr76533869165338757+intron-Distal4.681636.42243HepG2GTF2F1
chr76536156965361651+intron-Distal5.2879130.34264HepG2PTBP1
chr76534474265344791+intron-Distal4.2941812.33192K562PTBP1
chr76536611065366214+intron-Distal3.254425.53952K562SAFB2
chr76538262465382729+intron-Distal3.338643.76460HepG2HNRNPL
chr76533893665338999+intron-Distal3.806085.70158K562EWSR1
chr76536155265361647+intron-Distal4.934288.98402K562PCBP1
chr76535866665358793+intron-Distal4.409885.44709K562KHSRP
chr76533868365338761+intron-Distal6.4085620.14891K562GTF2F1
chr76538449365384608+intron-Distal4.162993.62025K562MATR3
chr76533869265338759+intron-Distal4.6441812.09209K562DROSHA
chr76536964665369720+intron-Distal4.876377.87150K562KHDRBS1
chr76536155965361665+intron-Distal5.3907131.82275HepG2PCBP2
chr76540928765409340+intron-Distal4.066453.06853K562LIN28B
chr76533880665338872+intron-Distal3.7900911.28402HepG2FAM120A
chr76537468365374772+intron-Distal4.844415.17678K562EIF4G2
chr76533869765338758+intron-Distal3.186683.01707K562SLTM
chr76534214865342250+intron-Distal4.361235.41654K562KHSRP
chr76533892065338975+intron-Distal5.7423111.70978HepG2FAM120A
chr76533889765338972+intron-Distal3.507867.70534HepG2PRPF4
chr76536852465368597+intron-Distal3.897863.18711HepG2ILF3
chr76538998065390063+intron-Distal3.770023.16028HepG2SUGP2
chr76539532765395429+intron-Distal3.856886.29995HepG2HNRNPM
chr76538519565385267+intron-Distal3.582343.62418K562PTBP1
chr76539025165390396+intron-Distal4.182323.90241K562MATR3
chr76533887265338918+intron-Distal4.0512910.42969HepG2FAM120A
chr76533882665338942+intron-Distal3.332834.77759K562XRN2
chr76533881765338940+intron-Distal3.483163.00103HepG2DROSHA
chr76533887565338959+intron-Distal3.684409.55557K562DROSHA
chr76535748565357587+intron-Distal3.901583.26999K562KHSRP
chr76537836165378398+intron-Distal4.015513.06853K562LIN28B
chr76540502765405081+intron-Distal3.222924.34612K562SAFB2
chr76537096365371053+intron-Distal3.697433.89405HepG2PTBP1
chr76533881165338871+intron-Distal3.401394.25110K562CSTF2T
chr76533879865338877+intron-Distal4.8875412.16562K562GTF2F1
chr76533879965338864+intron-Distal4.338979.56617HepG2CSTF2T
chr76533887565338928+intron-Distal5.5318412.33690K562CSTF2T
chr76533891965338983+intron-Distal4.9023215.07994HepG2CSTF2T
chr76536156365361660+intron-Distal3.6903110.08293K562ILF3
chr76533883165338884+intron-Distal4.330543.87357K562EWSR1
chr76533872165338761+intron-Distal5.113934.56340K562DDX51
chr76533869465338766+intron-Distal5.5432913.26784K562CSTF2T
chr76536504265365100+intron-Distal4.258094.62276K562TARDBP
chr76536157965361652+intron-Distal5.0373223.06264K562PTBP1
chr76533887165339022+intron-Distal3.905293.52365K562FUS
chr76535309165353180+intron-Distal3.778415.91510K562TARDBP
chr76537530565375387+intron-Distal3.976113.80954K562HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for VKORC1L1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for VKORC1L1 is not available on ENCORE database.

  • 101 RBPs can affect the levels of VKORC1L1.  








The Knockdown/knockout RNA-Seq assay for VKORC1L1 is not available on ENCORE database.





101 RBPs can affect the gene expression of VKORC1L1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
VKORC1L1ENSG00000196715.51037.799401622.05380-0.644305.496904.21850HepG2ABCF1
VKORC1L1ENSG00000196715.51001.174801308.75780-0.386503.600102.73870HepG2AKAP8L
VKORC1L1ENSG00000196715.51064.254101781.97810-0.743609.051207.68350HepG2ASCC1
VKORC1L1ENSG00000196715.5884.360101196.50750-0.436102.400601.52870HepG2BCCIP
VKORC1L1ENSG00000196715.5781.078301039.75660-0.412702.323101.50200HepG2BCLAF1
VKORC1L1ENSG00000196715.51321.414602089.79050-0.661304.471503.21560HepG2CCAR1
VKORC1L1ENSG00000196715.51083.265201692.99530-0.644207.181305.97960HepG2CIRBP
VKORC1L1ENSG00000196715.5885.926701302.39170-0.555906.365305.43170HepG2CKAP4
VKORC1L1ENSG00000196715.5872.995801338.69420-0.616803.738502.84230HepG2CNOT7
VKORC1L1ENSG00000196715.5524.11160739.19620-0.496103.511002.31250HepG2CSTF2
VKORC1L1ENSG00000196715.51522.105601855.37410-0.285604.376903.47810HepG2DAZAP1
VKORC1L1ENSG00000196715.5841.124801101.53860-0.389103.163302.44150HepG2DDX21
VKORC1L1ENSG00000196715.5846.755801176.37100-0.474302.828602.04730HepG2DDX55
VKORC1L1ENSG00000196715.5852.367101082.57690-0.344902.608501.65490HepG2DHX30
VKORC1L1ENSG00000196715.5983.950901246.15640-0.340802.537601.88580HepG2DKC1
VKORC1L1ENSG00000196715.5787.500701122.41780-0.511306.810405.74610HepG2DNAJC21
VKORC1L1ENSG00000196715.5754.254501112.53100-0.5607010.544509.36920HepG2DNAJC2
VKORC1L1ENSG00000196715.5779.588601113.67820-0.514504.144403.03960HepG2EEF2
VKORC1L1ENSG00000196715.5696.92070928.46770-0.413902.865401.73820HepG2EFTUD2
VKORC1L1ENSG00000196715.5902.248201703.68100-0.9171012.7824011.56880HepG2EIF2S1
VKORC1L1ENSG00000196715.51265.528601882.81770-0.573204.955904.10330HepG2EIF4A3
VKORC1L1ENSG00000196715.51303.727301833.09200-0.491603.135402.40610HepG2EIF4B
VKORC1L1ENSG00000196715.51033.049101637.99500-0.665005.667704.60480HepG2FIP1L1
VKORC1L1ENSG00000196715.51352.996101899.53300-0.489504.475003.60980HepG2FXR1
VKORC1L1ENSG00000196715.5967.379901762.17490-0.8652010.960509.67890HepG2G3BP1
VKORC1L1ENSG00000196715.5587.20220804.98340-0.455103.211902.23830HepG2GEMIN5
VKORC1L1ENSG00000196715.51013.928901736.52620-0.776208.991107.88090HepG2GPKOW
VKORC1L1ENSG00000196715.5431.344201133.17120-1.3935028.0977026.44120HepG2HNRNPA1
VKORC1L1ENSG00000196715.5798.386901260.45150-0.658807.830706.71260HepG2HNRNPC
VKORC1L1ENSG00000196715.51047.629901259.55150-0.265802.341901.67840HepG2HNRNPF
VKORC1L1ENSG00000196715.51270.879901690.12440-0.411307.928606.84150HepG2HNRNPL
VKORC1L1ENSG00000196715.51191.585401657.19810-0.475904.250903.48550HepG2HNRNPLL
VKORC1L1ENSG00000196715.5713.070501130.45120-0.664806.384005.01900HepG2HNRNPM
VKORC1L1ENSG00000196715.5863.389601252.11760-0.536308.996507.95130HepG2HNRNPU
VKORC1L1ENSG00000196715.5886.348001240.31040-0.484805.256604.29180HepG2IGF2BP1
VKORC1L1ENSG00000196715.51237.939801791.24060-0.533005.143704.24850HepG2IGF2BP2
VKORC1L1ENSG00000196715.5974.206901278.99530-0.392706.549705.46970HepG2ILF2
VKORC1L1ENSG00000196715.51346.962802205.48400-0.711405.558604.36720HepG2LARP4
VKORC1L1ENSG00000196715.5916.005901201.98450-0.392002.908301.66260HepG2LIN28B
VKORC1L1ENSG00000196715.51028.726901900.19550-0.8853012.2292010.88480HepG2MAGOH
VKORC1L1ENSG00000196715.51238.897301955.88660-0.658807.055406.06660HepG2NCBP2
VKORC1L1ENSG00000196715.51462.692201839.78150-0.330903.732602.84450HepG2NOL12
VKORC1L1ENSG00000196715.51404.127201741.93640-0.311001.986301.36620HepG2PABPC4
VKORC1L1ENSG00000196715.5652.036301239.37190-0.9266022.2713020.31910HepG2PARN
VKORC1L1ENSG00000196715.51337.994901792.01460-0.421507.130806.23090HepG2PCBP1
VKORC1L1ENSG00000196715.5843.663801388.46900-0.718805.394503.97940HepG2PCBP2
VKORC1L1ENSG00000196715.5377.62260907.71660-1.2653017.1627015.39870HepG2PRPF8
VKORC1L1ENSG00000196715.51248.141301823.38110-0.5468010.9629010.01420HepG2PTBP1
VKORC1L1ENSG00000196715.51162.688601756.21360-0.595008.134407.18470HepG2PUF60
VKORC1L1ENSG00000196715.51543.537501864.27610-0.272404.085503.39470HepG2PUM1
VKORC1L1ENSG00000196715.51584.970301862.92810-0.233101.994701.41920HepG2PUM2
VKORC1L1ENSG00000196715.5923.790301326.67090-0.522206.190605.33500HepG2PUS1
VKORC1L1ENSG00000196715.5976.900401339.93210-0.455901.997001.38830HepG2RAVER1
VKORC1L1ENSG00000196715.51509.403901895.63270-0.328703.918803.33030HepG2RBM22
VKORC1L1ENSG00000196715.5870.983201120.75020-0.363702.264101.30780HepG2RCC2
VKORC1L1ENSG00000196715.51382.517202029.29860-0.5537011.4936010.53540HepG2NELFE
VKORC1L1ENSG00000196715.51454.727201889.92430-0.377605.941805.08530HepG2RECQL
VKORC1L1ENSG00000196715.5899.436301356.67030-0.593005.589204.66880HepG2RPLP0
VKORC1L1ENSG00000196715.5447.25620879.69210-0.9759014.6008013.33830HepG2RPS19
VKORC1L1ENSG00000196715.5844.185001272.91440-0.592505.762104.63330HepG2RPS2
VKORC1L1ENSG00000196715.5886.413401343.81340-0.600304.364603.35870HepG2RPS3A
VKORC1L1ENSG00000196715.51406.159201898.48400-0.433107.502006.60640HepG2SF3B4
VKORC1L1ENSG00000196715.51427.390601683.88950-0.238403.021002.29200HepG2SLBP
VKORC1L1ENSG00000196715.51060.762701300.34180-0.293803.772403.04120HepG2SMN1
VKORC1L1ENSG00000196715.51041.262101366.07680-0.391702.150901.31740HepG2SMNDC1
VKORC1L1ENSG00000196715.51742.421302141.06380-0.297204.362803.77520HepG2SRFBP1
VKORC1L1ENSG00000196715.51740.606301981.56180-0.187002.047401.62330HepG2SRSF1
VKORC1L1ENSG00000196715.51255.875001733.97850-0.465408.129607.12940HepG2SRSF5
VKORC1L1ENSG00000196715.5993.810901237.42730-0.316303.092202.36210HepG2SRSF7
VKORC1L1ENSG00000196715.51418.519601858.97890-0.390106.418205.69640HepG2SSB
VKORC1L1ENSG00000196715.51526.967501972.03400-0.369006.750705.85440HepG2SUCLG1
VKORC1L1ENSG00000196715.5627.362501171.12920-0.900509.149108.03740HepG2SUPV3L1
VKORC1L1ENSG00000196715.5915.589101780.98170-0.9599025.9218024.43700HepG2TAF15
VKORC1L1ENSG00000196715.5898.044101483.04760-0.723703.298702.13650HepG2TBRG4
VKORC1L1ENSG00000196715.5532.604701216.63570-1.1918028.0310026.74700HepG2TIAL1
VKORC1L1ENSG00000196715.51434.972601715.71000-0.257802.076101.32890HepG2TUFM
VKORC1L1ENSG00000196715.51106.886801401.47410-0.340402.085701.53230HepG2U2AF1
VKORC1L1ENSG00000196715.5942.454701338.03180-0.505608.813507.68630HepG2UPF1
VKORC1L1ENSG00000196715.5697.260201072.58030-0.621303.509302.36950HepG2UPF2
VKORC1L1ENSG00000196715.5704.847501152.84620-0.709806.606805.50190HepG2XRN2
VKORC1L1ENSG00000196715.51337.879001606.05620-0.263602.913002.33220K562AGGF1
VKORC1L1ENSG00000196715.51384.085101671.16170-0.271901.994301.43800K562AKAP8L
VKORC1L1ENSG00000196715.52012.488402645.15120-0.394402.776602.18770K562AQR
VKORC1L1ENSG00000196715.51260.498702126.57230-0.7545014.3712012.55260K562CPSF6
VKORC1L1ENSG00000196715.52999.541602638.479200.184902.011701.44050K562DDX47
VKORC1L1ENSG00000196715.51046.123201473.90140-0.494604.427803.25610K562EFTUD2
VKORC1L1ENSG00000196715.51075.263901328.84910-0.305503.478502.10690K562EIF2S1
VKORC1L1ENSG00000196715.51603.805302304.78760-0.523106.936305.87330K562EIF2S2
VKORC1L1ENSG00000196715.5907.511301263.94200-0.477904.690903.62340K562EIF4A3
VKORC1L1ENSG00000196715.51413.875202351.80180-0.7341011.625309.76060K562FIP1L1
VKORC1L1ENSG00000196715.51937.207401314.445200.5594010.567409.47100K562FXR1
VKORC1L1ENSG00000196715.51476.231902030.39180-0.459805.138804.06180K562GPKOW
VKORC1L1ENSG00000196715.52139.193903071.62710-0.521904.967703.95660K562GRSF1
VKORC1L1ENSG00000196715.5789.005701457.02320-0.884909.133908.09970K562HNRNPC
VKORC1L1ENSG00000196715.51481.271401934.30170-0.385002.831001.88900K562HNRNPM
VKORC1L1ENSG00000196715.51530.717801922.18630-0.328503.919302.85090K562HNRNPU
VKORC1L1ENSG00000196715.52615.705703188.66860-0.285802.442801.69180K562HSPD1
VKORC1L1ENSG00000196715.51127.336701581.94680-0.488803.676602.43030K562IGF2BP2
VKORC1L1ENSG00000196715.51243.561201981.87270-0.6724010.407408.63280K562METAP2
VKORC1L1ENSG00000196715.51562.136501967.78210-0.333005.068604.00000K562MTPAP
VKORC1L1ENSG00000196715.51829.654602186.51370-0.257103.813302.95290K562NSUN2
VKORC1L1ENSG00000196715.51062.044201434.19030-0.433403.418001.77430K562NUSAP1
VKORC1L1ENSG00000196715.51449.036801980.97960-0.451103.835802.85650K562PCBP3
VKORC1L1ENSG00000196715.51240.531001519.43550-0.292602.432901.68440K562POLR2G
VKORC1L1ENSG00000196715.52101.712602669.63210-0.345103.093002.21730K562PPIG
VKORC1L1ENSG00000196715.51032.378001434.27080-0.474304.051703.14230K562PRPF8
VKORC1L1ENSG00000196715.5916.735801306.30360-0.510903.656402.59740K562PSIP1
VKORC1L1ENSG00000196715.51184.531501549.31360-0.387303.420702.48090K562RBM22
VKORC1L1ENSG00000196715.5966.846601461.10920-0.595704.982003.88450K562RPS19
VKORC1L1ENSG00000196715.51657.314501353.989800.291502.338201.34930K562SAFB
VKORC1L1ENSG00000196715.51858.888902157.33610-0.214802.230601.49210K562SF3A3
VKORC1L1ENSG00000196715.51057.053701353.51580-0.356702.189601.43020K562SF3B4
VKORC1L1ENSG00000196715.51026.103201304.88280-0.346703.577102.08780K562SSB
VKORC1L1ENSG00000196715.51051.088301388.93980-0.402102.656201.66130K562SUPV3L1
VKORC1L1ENSG00000196715.52093.758001524.093300.458006.223304.98510K562SYNCRIP
VKORC1L1ENSG00000196715.51289.687301546.20390-0.261702.033101.33830K562TIA1
VKORC1L1ENSG00000196715.5975.479101256.48670-0.365202.300101.45280K562TIAL1
VKORC1L1ENSG00000196715.51084.552601469.89380-0.438603.533902.37430K562UCHL5
VKORC1L1ENSG00000196715.51841.062702318.39640-0.332604.172103.30750K562UPF1
VKORC1L1ENSG00000196715.51355.334601983.79550-0.549607.778106.26680K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for VKORC1L1 is not available on ENCORE database.





6 RBPs can affect the splicing of VKORC1L1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEVKORC1L1ENSG00000196715.5chr7+654136576541376765338253653385526541906065424550-0.351000.000000.00000excludedK562AKAP8L
SEVKORC1L1ENSG00000196715.5chr7+654136576541376765338253653385526541906065424550-0.190000.000500.01523excludedHepG2HNRNPK
SEVKORC1L1ENSG00000196715.5chr7+654136576541376765338253653385526541906065424550-0.369000.000000.00000excludedK562PUS1
SEVKORC1L1ENSG00000196715.5chr7+654136576541376765338253653385526541906065424550-0.345000.000000.00000excludedK562UTP18
SEVKORC1L1ENSG00000196715.5chr7+654136576541376765338253653385526541906065424550-0.411000.000000.00000excludedK562RBM15
SEVKORC1L1ENSG00000196715.5chr7+654136576541376765338253653385526541906065424550-0.313000.000000.00008excludedK562AGGF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for VKORC1L1 is not avaliable on ENCORE database.