SRGAP2

General Information

Gene Name       : SRGAP2
Gene ID             : ENSG00000266028.7
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SRGAP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SRGAP2ENSG00000266028.73.334.704.02ENCSR000AEF
HepG2SRGAP2ENSG00000266028.724.5620.9222.74ENCSR985KAT
K562SRGAP2ENSG00000266028.717.1617.7217.44ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SRGAP2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SRGAP2 RNA is bound by 21 proteins.  







eCLIP assay for SRGAP2 is not avaliable on ENCORE database.





21 proteins are bound to SRGAP2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1206610293206610407+3'-UTR,CDS,intron-Proximal3.166683.50696K562BUD13
chr1206628606206628663+3'-UTR,intron-Distal4.639199.43510K562UPF1
chr1206619538206619613+3'-UTR,CDS3.984843.19539K562YBX3
chr1206635234206635270+3'-UTR3.608319.89269HepG2HNRNPL
chr1206635212206635361+3'-UTR3.463087.51876K562HNRNPL
chr1206610321206610393+3'-UTR,CDS,intron-Proximal3.453697.87154HepG2PPIG
chr1206635267206635308+3'-UTR3.967696.22491K562AGGF1
chr1206635021206635075+3'-UTR3.166143.87237HepG2HNRNPL
chr1206610318206610393+3'-UTR,CDS,intron-Proximal3.513735.11891HepG2GRWD1
chr1206619567206619623+3'-UTR,CDS3.107183.79741HepG2GRWD1
chr1206628766206628814+3'-UTR,intron-Distal4.084375.99105K562UPF1
chr1206635218206635234+3'-UTR3.469017.30047HepG2HNRNPL
chr1206634978206635051+3'-UTR3.984643.59673K562HNRNPL
chr1206629020206629125+3'-UTR,intron-Distal,intron-Proximal3.201936.04421HepG2U2AF2
chr1206629053206629122+3'-UTR,intron-Distal,intron-Proximal3.439354.23616K562TIA1
chr1206603509206603587+3'-UTR,CDS,intron-Proximal3.822433.00996K562BUD13
chr1206635291206635319+3'-UTR3.221656.72570HepG2HNRNPL
chr1206635270206635291+3'-UTR3.4176311.15029HepG2HNRNPL
chr1206635194206635218+3'-UTR4.274006.61771HepG2HNRNPL
chr1206629047206629087+3'-UTR,intron-Distal,intron-Proximal3.700465.32141K562UPF1
chr1206611312206611346+3'-UTR,CDS,intron-Proximal3.562486.81103HepG2PPIG
chr1206566911206566974+5'-UTR,CDS4.503088.85766HepG2BCLAF1
chr1206592721206592792+5'-UTR,CDS,intron-Proximal4.158643.83824K562BUD13
chr1206566200206566262+5'-UTR,CDS,intron-Proximal5.229627.95223HepG2BCLAF1
chr1206566901206566983+5'-UTR,CDS,intron-Proximal4.729545.86954K562UCHL5
chr1206566110206566216+5'-UTR,CDS3.217774.76953K562DDX24
chr1206566198206566264+5'-UTR,CDS,intron-Proximal4.255566.61895K562ZNF622
chr1206589326206589378+5'-UTR,CDS,intron-Proximal4.369556.48405K562AQR
chr1206589290206589335+5'-UTR,CDS,intron-Proximal3.110914.24993HepG2PPIG
chr1206592750206592798+5'-UTR,CDS,intron-Proximal5.582407.81430K562AQR
chr1206567021206567084+5'-UTR,CDS,intron-Proximal4.499845.34978HepG2PRPF8
chr1206567018206567094+5'-UTR,CDS,intron-Proximal3.791915.58816K562PRPF8
chr1206566897206566982+5'-UTR,CDS,intron-Proximal3.094595.92720K562ZNF622
chr1206589326206589379+5'-UTR,CDS,intron-Proximal4.6000314.23871HepG2PRPF8
chr1206594554206594667+5'-UTR,CDS,intron-Proximal4.280788.63922HepG2PRPF8
chr1206566101206566200+5'-UTR,CDS3.185607.87063HepG2GRWD1
chr1206592689206592796+5'-UTR,CDS,intron-Proximal5.367479.24583HepG2AQR
chr1206589253206589334+5'-UTR,CDS,intron-Proximal4.482364.78571K562UCHL5
chr1206566901206566971+5'-UTR,CDS,intron-Proximal3.157676.61645HepG2BUD13
chr1206566200206566262+5'-UTR,CDS,intron-Proximal3.437117.67656HepG2GRWD1
chr1206566900206566984+5'-UTR,CDS,intron-Proximal4.110165.98894K562ZNF800
chr1206566116206566209+5'-UTR,CDS4.036727.16955K562UCHL5
chr1206566900206566911+5'-UTR,CDS,intron-Proximal3.791074.09885HepG2BCLAF1
chr1206589316206589411+5'-UTR,CDS,intron-Proximal3.191237.07421HepG2BUD13
chr1206592747206592763+5'-UTR,CDS,intron-Proximal3.809489.86827HepG2PRPF8
chr1206566898206566981+5'-UTR,CDS,intron-Proximal3.064426.07026HepG2GRWD1
chr1206626526206626581+CDS,intron-Proximal4.151573.35169HepG2U2AF2
chr1206628261206628331+CDS3.818516.76837K562UPF1
chr1206626680206626741+CDS,intron-Proximal3.761504.96634HepG2PPIG
chr1206631902206631973+CDS,intron-Proximal5.8082114.32392HepG2SF3B4
chr1206632249206632300+CDS,intron-Proximal3.957764.01763HepG2GRWD1
chr1206628206206628253+CDS,intron-Proximal3.675447.89103HepG2U2AF2
chr1206626720206626784+CDS,intron-Proximal4.6733310.42975HepG2PRPF8
chr1206628176206628261+CDS,intron-Proximal4.3084221.16246K562UPF1
chr1206623792206623858+CDS,intron-Proximal4.048067.26133HepG2PRPF8
chr1206626624206626736+CDS,intron-Proximal3.736756.02304HepG2GRWD1
chr1206628188206628254+CDS,intron-Proximal3.320544.16903HepG2U2AF1
chr1206519104206519120+intron-Distal6.37613400.00000HepG2DKC1
chr1206564994206565066+intron-Distal3.943935.29549HepG2HNRNPL
chr1206574545206574600+intron-Distal3.013154.43994HepG2U2AF2
chr1206565021206565045+intron-Distal4.199663.86413K562AGGF1
chr1206563132206563188+intron-Distal3.767793.29248HepG2SUGP2
chr1206519082206519162+intron-Distal3.2982430.19703HepG2NOLC1
chr1206564934206565058+intron-Distal4.007403.37631K562HNRNPL
chr1206519161206519165+intron-Distal8.61066400.00000HepG2DKC1
chr1206519120206519161+intron-Distal6.94830400.00000HepG2DKC1
chr1206627679206627722+intron-Distal4.680705.63383K562UPF1
chr1206519076206519093+intron-Distal7.29795400.00000HepG2DKC1
chr1206628186206628206+intron-Proximal3.777343.62357HepG2U2AF2
chr1206628132206628180+intron-Proximal4.051013.81705HepG2SF3B4
chr1206592763206592838+intron-Proximal3.9727411.10668HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SRGAP2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SRGAP2 is not available on ENCORE database.

  • 104 RBPs can affect the levels of SRGAP2.  








The Knockdown/knockout RNA-Seq assay for SRGAP2 is not available on ENCORE database.





104 RBPs can affect the gene expression of SRGAP2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SRGAP2ENSG00000163486.81775.453902653.27710-0.579604.514303.33270HepG2ABCF1
SRGAP2ENSG00000163486.82340.767401979.219200.242003.342102.68380HepG2ACO1
SRGAP2ENSG00000163486.81458.796902195.91750-0.590005.261704.55700HepG2AKAP1
SRGAP2ENSG00000163486.81454.193301816.96800-0.321302.157301.46030HepG2ASCC1
SRGAP2ENSG00000163486.82380.018802886.83280-0.278504.108003.30180HepG2AUH
SRGAP2ENSG00000163486.81169.603101642.82810-0.490203.526602.46990HepG2BCCIP
SRGAP2ENSG00000163486.8964.471101427.51540-0.565704.618303.48080HepG2BCLAF1
SRGAP2ENSG00000163486.8946.474502180.53270-1.2040025.9608024.43480HepG2BOP1
SRGAP2ENSG00000163486.81585.003302120.11390-0.419705.274804.25200HepG2CALR
SRGAP2ENSG00000163486.8996.435301726.23480-0.7928010.509609.09000HepG2CIRBP
SRGAP2ENSG00000163486.81615.251401978.86770-0.292904.648203.82940HepG2CKAP4
SRGAP2ENSG00000163486.81549.474102001.88880-0.369602.975702.26580HepG2CPSF6
SRGAP2ENSG00000163486.81443.167101981.86090-0.457607.163905.54240HepG2YBX3
SRGAP2ENSG00000163486.82161.747302659.42660-0.298905.717804.70650HepG2DAZAP1
SRGAP2ENSG00000163486.81577.830401830.53040-0.214302.555201.75130HepG2DDX19B
SRGAP2ENSG00000163486.8919.029001618.90280-0.8168013.2169011.87180HepG2DDX21
SRGAP2ENSG00000163486.81009.593501511.35130-0.582104.348802.78180HepG2DDX27
SRGAP2ENSG00000163486.81453.764002103.58860-0.533105.047804.22470HepG2DDX3X
SRGAP2ENSG00000163486.81970.955902614.45680-0.407603.549602.08480HepG2DDX47
SRGAP2ENSG00000163486.81231.156801615.22770-0.391702.435401.70570HepG2DDX55
SRGAP2ENSG00000163486.81716.446902168.70830-0.337402.765501.75400HepG2DDX5
SRGAP2ENSG00000163486.81384.302101876.96320-0.439204.607303.35660HepG2DHX30
SRGAP2ENSG00000163486.81298.630301893.59680-0.5441010.889609.72890HepG2DKC1
SRGAP2ENSG00000163486.81443.843201946.05510-0.430606.541605.49460HepG2DNAJC21
SRGAP2ENSG00000163486.81704.045201928.84720-0.178802.108601.52500HepG2DNAJC2
SRGAP2ENSG00000163486.8877.844901737.14280-0.9847014.5041013.21450HepG2EIF2S1
SRGAP2ENSG00000163486.81048.645401919.82130-0.8724010.518509.29370HepG2EIF4A3
SRGAP2ENSG00000163486.81919.212802623.59560-0.451009.072807.72180HepG2EIF4G1
SRGAP2ENSG00000163486.82664.213003314.60880-0.315105.261704.47950HepG2ETF1
SRGAP2ENSG00000163486.81008.026401272.77620-0.336403.151001.89040HepG2FAM120A
SRGAP2ENSG00000163486.83807.854002679.326000.507005.163704.14100HepG2FIP1L1
SRGAP2ENSG00000163486.8998.047301344.45260-0.429802.965101.65390HepG2FKBP4
SRGAP2ENSG00000163486.82359.265101936.794500.284601.882501.30720HepG2FXR1
SRGAP2ENSG00000163486.81819.605502269.40930-0.318702.033701.47960HepG2GPKOW
SRGAP2ENSG00000163486.81789.824102444.03770-0.449408.436206.96930HepG2HNRNPA2B1
SRGAP2ENSG00000163486.81412.059902185.35610-0.630108.877207.68710HepG2HNRNPC
SRGAP2ENSG00000163486.81891.873602246.24170-0.247702.809702.08690HepG2HNRNPF
SRGAP2ENSG00000163486.81848.822502422.56650-0.389908.876207.73460HepG2HNRNPL
SRGAP2ENSG00000163486.81357.129702165.72890-0.674308.402707.37020HepG2HNRNPLL
SRGAP2ENSG00000163486.81330.496501849.04400-0.474805.143803.88960HepG2HNRNPM
SRGAP2ENSG00000163486.81640.268902170.90840-0.404407.405206.45080HepG2HNRNPU
SRGAP2ENSG00000163486.81732.825902211.92020-0.352203.770102.93560HepG2IGF2BP1
SRGAP2ENSG00000163486.81748.448702217.51240-0.342907.136006.01800HepG2ILF2
SRGAP2ENSG00000163486.81535.402401937.46970-0.335602.287301.68900HepG2MAGOH
SRGAP2ENSG00000163486.81413.185801948.35000-0.463303.543602.83770HepG2MATR3
SRGAP2ENSG00000163486.81663.001202208.51650-0.409302.242701.37640HepG2MTPAP
SRGAP2ENSG00000163486.82133.951502637.07620-0.305403.649002.77260HepG2NOL12
SRGAP2ENSG00000163486.81766.271402416.42330-0.452203.333801.40320HepG2PPIG
SRGAP2ENSG00000163486.81546.158701936.27820-0.324603.942703.07840HepG2PPIL4
SRGAP2ENSG00000163486.81512.294902127.48050-0.492409.762608.44170HepG2PRPF4
SRGAP2ENSG00000163486.82358.116901708.016300.465208.592607.73900HepG2PTBP1
SRGAP2ENSG00000163486.81592.288402517.29040-0.6608010.845909.76970HepG2PUF60
SRGAP2ENSG00000163486.81982.757002672.18010-0.4305011.3084010.27890HepG2PUM1
SRGAP2ENSG00000163486.82039.560102670.24980-0.388705.180104.27580HepG2PUM2
SRGAP2ENSG00000163486.81740.870702015.97460-0.211702.487001.89490HepG2PUS1
SRGAP2ENSG00000163486.82045.029701770.360000.208002.106201.55890HepG2RECQL
SRGAP2ENSG00000163486.81899.745902419.55360-0.348903.134902.41470HepG2RPLP0
SRGAP2ENSG00000163486.81257.238801773.66980-0.496502.873301.91260HepG2RPS10
SRGAP2ENSG00000163486.81552.445402247.87730-0.534003.868202.92210HepG2RPS3A
SRGAP2ENSG00000163486.81458.919201933.29460-0.406207.630206.63830HepG2SAFB2
SRGAP2ENSG00000163486.81563.243102287.19360-0.549004.307503.45640HepG2SF3A3
SRGAP2ENSG00000163486.8905.816202143.70870-1.2428026.0656024.16020HepG2SF3B1
SRGAP2ENSG00000163486.81989.401802413.61760-0.278904.740403.86040HepG2SLBP
SRGAP2ENSG00000163486.81505.104502385.22850-0.664304.787903.74680HepG2SNRNP70
SRGAP2ENSG00000163486.82705.040703128.98080-0.210003.218602.69150HepG2SRFBP1
SRGAP2ENSG00000163486.82180.397501856.172400.232202.705802.23690HepG2SRSF1
SRGAP2ENSG00000163486.82095.772602485.41580-0.246003.245502.57680HepG2SRSF5
SRGAP2ENSG00000163486.81757.361702206.81230-0.328604.583303.72110HepG2SRSF7
SRGAP2ENSG00000163486.81273.957201510.06840-0.245302.787102.23400HepG2SRSF9
SRGAP2ENSG00000163486.81400.250602716.60700-0.9561038.7075037.30900HepG2SSB
SRGAP2ENSG00000163486.81091.807901809.78690-0.729109.161207.53180HepG2SUPT6H
SRGAP2ENSG00000163486.82202.755501668.314100.400805.693504.93870HepG2TAF15
SRGAP2ENSG00000163486.81750.346402110.61740-0.270001.929401.30930HepG2TARDBP
SRGAP2ENSG00000163486.8811.553201077.77030-0.409302.838301.82940HepG2TFIP11
SRGAP2ENSG00000163486.81344.725202109.47250-0.6496011.7927010.88690HepG2TIAL1
SRGAP2ENSG00000163486.81442.159202128.29820-0.5615012.8852011.79330HepG2TRIM56
SRGAP2ENSG00000163486.82071.285302459.22920-0.247702.158201.39310HepG2TUFM
SRGAP2ENSG00000163486.81742.700502292.37290-0.395503.155902.48820HepG2U2AF1
SRGAP2ENSG00000163486.81432.636902028.39010-0.5017010.754309.54180HepG2UPF1
SRGAP2ENSG00000163486.81014.060801472.45420-0.538103.330502.22500HepG2UPF2
SRGAP2ENSG00000163486.81442.269501958.33240-0.441307.741506.82080HepG2UTP3
SRGAP2ENSG00000163486.81395.972102013.42620-0.528403.574502.32060HepG2XPO5
SRGAP2ENSG00000163486.81140.794401582.85610-0.472503.844202.99800HepG2XRN2
SRGAP2ENSG00000163486.82381.805202099.598500.181802.164901.56010HepG2ZC3H8
SRGAP2ENSG00000163486.81213.407002230.84220-0.8785036.7057035.30360HepG2ZNF622
SRGAP2ENSG00000163486.81824.549102370.93190-0.377903.697402.93890K562AKAP8L
SRGAP2ENSG00000163486.82138.113401723.011600.311302.597302.02450K562AQR
SRGAP2ENSG00000163486.81824.534802487.66900-0.447307.164605.60190K562ATP5C1
SRGAP2ENSG00000163486.81227.18890957.466300.358003.808202.21170K562BCCIP
SRGAP2ENSG00000163486.82437.529301769.900800.461702.301201.35040K562CNOT7
SRGAP2ENSG00000163486.81891.296401270.460700.5739010.795609.51720K562EIF2S2
SRGAP2ENSG00000163486.82152.067801250.099100.7836011.8948010.04390K562FMR1
SRGAP2ENSG00000163486.81518.963801059.583300.519504.690303.47100K562FTO
SRGAP2ENSG00000163486.8793.992701101.99160-0.472903.413702.37140K562HNRNPM
SRGAP2ENSG00000163486.82451.836001816.402200.432704.428803.42780K562HSPD1
SRGAP2ENSG00000163486.81591.723401001.625200.668105.615504.22450K562KRR1
SRGAP2ENSG00000163486.81325.86910912.695200.538605.891903.76010K562LARP7
SRGAP2ENSG00000163486.81259.16090955.898900.397403.026501.49320K562LIN28B
SRGAP2ENSG00000163486.81391.996701144.984300.281702.175101.39760K562METAP2
SRGAP2ENSG00000163486.8668.54990889.08430-0.411302.758001.46850K562NONO
SRGAP2ENSG00000163486.81846.320501555.341500.247303.497902.66830K562NSUN2
SRGAP2ENSG00000163486.82340.803501555.886300.589206.167804.92140K562PCBP3
SRGAP2ENSG00000163486.81761.216301193.420500.561408.224706.86990K562POLR2G
SRGAP2ENSG00000163486.81990.052402531.12970-0.347003.933902.63990K562PUM1
SRGAP2ENSG00000163486.81761.325202351.34930-0.416803.706203.09090K562PUS1
SRGAP2ENSG00000163486.82054.761601241.595900.726702.713301.52860K562SF1
SRGAP2ENSG00000163486.81815.096001534.692900.242002.463901.69150K562SF3A3
SRGAP2ENSG00000163486.81676.754601115.605400.587705.407904.01540K562SF3B1
SRGAP2ENSG00000163486.82164.981501572.323100.4614010.261108.58630K562SRPK2
SRGAP2ENSG00000163486.81112.85330863.476700.365902.957001.97300K562TRIM56
SRGAP2ENSG00000163486.81332.967901023.268700.381402.460601.44030K562U2AF1
SRGAP2ENSG00000163486.81921.805101649.159800.220602.456801.77870K562UPF1
SRGAP2ENSG00000163486.82505.131702041.626800.295102.697201.42570K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SRGAP2 is not available on ENCORE database.





7 RBPs can affect the splicing of SRGAP2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESRGAP2ENSG00000163486.8chr1+2066329302066330252066319682066322932066343812066377760.333000.003180.05280includedK562SRSF1
SESRGAP2ENSG00000163486.8chr1+2065646562065647792065573672065574312065660452065662610.086000.010990.08751includedK562AQR
SESRGAP2ENSG00000163486.8chr1+2066329302066330252066319682066322932066343812066377760.275000.000660.08030includedK562DROSHA
SESRGAP2ENSG00000163486.8chr1+206632930206633025206631968206632293206634381206637776-0.110000.001960.08555excludedHepG2PTBP1
SESRGAP2ENSG00000163486.8chr1+2066329302066330252066319682066322932066343812066377760.340000.000330.09180includedK562UCHL5
SESRGAP2ENSG00000163486.8chr1+2066329302066330252066319682066322932066343812066377760.149000.000440.03653includedHepG2IGF2BP3
SESRGAP2ENSG00000163486.8chr1+2066329302066330252066319682066322932066343812066377760.577000.000030.01361includedK562SERBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SRGAP2 is not avaliable on ENCORE database.