SP140L

General Information

Gene Name       : SP140L
Gene ID             : ENSG00000185404.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SP140L)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SP140LENSG00000185404.1618.1419.4418.79ENCSR000AEF
HepG2SP140LENSG00000185404.169.1614.7711.96ENCSR985KAT
K562SP140LENSG00000185404.1610.4310.4310.43ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SP140L is not avaliable on ENCORE database.



Proteins bound to RNA
  • SP140L RNA is bound by 13 proteins.  







eCLIP assay for SP140L is not avaliable on ENCORE database.





13 proteins are bound to SP140L RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2231256866231256946+CDS,intron-Proximal3.292143.94979HepG2BCLAF1
chr2231253272231253355+CDS,intron-Proximal4.594593.43980K562ZNF622
chr2231223671231223748+3'-UTR,CDS,intron-Proximal3.296364.74755K562ZNF622
chr2231226337231226413+CDS,intron-Proximal4.991346.71715HepG2BCLAF1
chr2231253276231253378+CDS,intron-Proximal3.695383.05298K562GRWD1
chr2231256833231256897+CDS3.009303.40321HepG2GRWD1
chr2231248220231248287+CDS,intron-Proximal3.440953.99381K562BUD13
chr2231249939231250009+CDS4.400534.42734K562UCHL5
chr2231249937231249992+CDS,intron-Proximal4.351883.43980K562ZNF622
chr2231223678231223755+3'-UTR,CDS,intron-Proximal3.480333.57857HepG2BCLAF1
chr2231253273231253351+CDS,intron-Proximal4.548265.29868K562UCHL5
chr2231256845231256974+CDS,intron-Proximal3.220364.14618K562ZNF622
chr2231248233231248293+CDS,intron-Proximal3.661094.74268K562UCHL5
chr2231248223231248291+CDS,intron-Proximal4.539706.36164K562DDX24
chr2231230378231230490+intron-Distal3.822323.16986HepG2QKI
chr2231211916231211973+intron-Distal4.951386.35761K562HNRNPM
chr2231264696231264761+intron-Distal,intron-Proximal3.701344.50744HepG2U2AF2
chr2231261590231261713+intron-Distal,intron-Proximal4.288113.89565K562PRPF8
chr2231198713231198778+intron-Distal4.296254.78128HepG2SUGP2
chr2231253446231253538+intron-Distal,intron-Proximal3.525554.08064K562KHSRP
chr2231196012231196096+intron-Distal3.920213.79098HepG2SUGP2
chr2231211842231211903+intron-Distal4.441185.16513HepG2HNRNPM
chr2231194995231195085+intron-Distal3.354876.28047HepG2SUGP2
chr2231253446231253575+intron-Distal,intron-Proximal3.230683.81210HepG2KHSRP
chr2231246389231246484+intron-Distal3.272876.22518HepG2HNRNPL
chr2231196668231196720+intron-Distal3.957213.63454HepG2SUGP2
chr2231211920231211964+intron-Distal4.204804.31871HepG2HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SP140L is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SP140L is not available on ENCORE database.

  • 96 RBPs can affect the levels of SP140L.  








The Knockdown/knockout RNA-Seq assay for SP140L is not available on ENCORE database.





96 RBPs can affect the gene expression of SP140L :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SP140LENSG00000185404.12831.61010520.084300.677105.269104.01370HepG2ABCF1
SP140LENSG00000185404.12579.54650395.767100.550205.924005.10040HepG2ACO1
SP140LENSG00000185404.12522.69380397.609600.394503.034202.23510HepG2AKAP8L
SP140LENSG00000185404.12876.66310554.764400.660006.179405.21760HepG2AUH
SP140LENSG00000185404.12772.46350461.191200.744008.302307.06950HepG2CALR
SP140LENSG00000185404.12889.63870654.432600.442902.435801.52740HepG2CCAR1
SP140LENSG00000185404.12662.84990345.045700.941809.652408.28240HepG2CIRBP
SP140LENSG00000185404.12838.59390395.660701.0836025.2700023.71780HepG2CKAP4
SP140LENSG00000185404.12532.14890334.960500.667703.365102.51540HepG2CNOT7
SP140LENSG00000185404.12693.91870517.946400.421904.089603.33730HepG2CELF1
SP140LENSG00000185404.12487.06420366.018500.412103.552202.62240HepG2DDX19B
SP140LENSG00000185404.12590.33200347.672600.763706.681005.67640HepG2DDX21
SP140LENSG00000185404.12487.20630339.890000.519403.489902.45640HepG2DDX24
SP140LENSG00000185404.12620.18400420.461200.560603.720403.00530HepG2DDX3X
SP140LENSG00000185404.12488.13880357.129900.450702.021301.34940HepG2DDX55
SP140LENSG00000185404.12609.11020418.883600.540103.905502.71240HepG2DDX5
SP140LENSG00000185404.12598.88720378.636600.661407.377306.37150HepG2DKC1
SP140LENSG00000185404.12522.33850308.665300.758806.257904.58510HepG2EFTUD2
SP140LENSG00000185404.12699.94390347.215501.0113010.638009.52260HepG2EIF2S1
SP140LENSG00000185404.12529.21610394.547900.423602.706801.55290HepG2EIF2S2
SP140LENSG00000185404.12440.74390328.097500.425702.484501.45960HepG2EIF3G
SP140LENSG00000185404.12510.59650383.709000.412102.040701.48910HepG2EIF4A3
SP140LENSG00000185404.12794.80220636.973800.319302.623002.03440HepG2ETF1
SP140LENSG00000185404.12655.70870386.717100.761708.319106.88070HepG2EWSR1
SP140LENSG00000185404.12762.68130525.165600.538203.236102.40920HepG2FIP1L1
SP140LENSG00000185404.121095.83980632.068600.793802.802801.78000HepG2FTO
SP140LENSG00000185404.12528.70950311.544200.762907.034705.81840HepG2FUBP3
SP140LENSG00000185404.12519.24500359.140900.531803.171002.46040HepG2G3BP1
SP140LENSG00000185404.12559.10820381.284300.552203.626402.59940HepG2G3BP2
SP140LENSG00000185404.12504.31370325.016500.633704.221202.96290HepG2GNB2L1
SP140LENSG00000185404.12628.94040330.711400.9273010.128709.00890HepG2HNRNPA1
SP140LENSG00000185404.12475.74460363.680900.387401.946601.35420HepG2HNRNPK
SP140LENSG00000185404.12522.50850365.056100.517203.115602.40410HepG2IGF2BP2
SP140LENSG00000185404.12482.67640373.278300.370703.142302.36520HepG2ILF2
SP140LENSG00000185404.12536.76470367.189300.547702.854001.83510HepG2KHSRP
SP140LENSG00000185404.12917.08600690.627700.409002.134501.41240HepG2LARP4
SP140LENSG00000185404.12509.88300387.296300.396601.954901.39950HepG2MAGOH
SP140LENSG00000185404.12579.89810425.057900.448003.078402.22710HepG2MSI2
SP140LENSG00000185404.12743.38140398.633600.898908.779807.68570HepG2NCBP2
SP140LENSG00000185404.12576.77410355.000300.700105.401404.40340HepG2PABPC4
SP140LENSG00000185404.12456.73810334.894900.447603.151702.51190HepG2PCBP1
SP140LENSG00000185404.12992.48980412.864401.2653013.4780011.45690HepG2PCBP2
SP140LENSG00000185404.12817.78300275.477601.5697015.2853013.60570HepG2PRPF8
SP140LENSG00000185404.12549.69840340.738900.689907.255706.45180HepG2PTBP1
SP140LENSG00000185404.12706.58140559.583000.336402.966002.35680HepG2PUM1
SP140LENSG00000185404.12662.40420369.090800.8436010.021408.93800HepG2QKI
SP140LENSG00000185404.12693.33210398.482200.798904.048303.20330HepG2RAVER1
SP140LENSG00000185404.121068.03450532.385901.0043020.1893019.05290HepG2RBM22
SP140LENSG00000185404.12664.05470334.950200.987307.387906.33140HepG2RBM25
SP140LENSG00000185404.12551.24010379.233900.539504.395803.74220HepG2NELFE
SP140LENSG00000185404.12500.55950353.160900.503103.834803.12510HepG2RECQL
SP140LENSG00000185404.12795.08280580.284300.454203.289102.55410HepG2RPLP0
SP140LENSG00000185404.12432.66470292.428200.565103.835203.12210HepG2RPS19
SP140LENSG00000185404.12488.22530354.133800.463202.523501.75710HepG2RPS2
SP140LENSG00000185404.12482.96300336.233000.522402.572901.80090HepG2RPS3A
SP140LENSG00000185404.12606.27380272.502501.1536011.131109.72020HepG2RRP9
SP140LENSG00000185404.12446.01960325.428700.454703.595602.87830HepG2SAFB2
SP140LENSG00000185404.12488.95700293.532500.736105.717504.37750HepG2SERBP1
SP140LENSG00000185404.12978.88110680.846400.523703.021302.31600HepG2SF3A3
SP140LENSG00000185404.121042.15920675.736000.624906.477205.43520HepG2SF3B1
SP140LENSG00000185404.12630.15980354.805500.8286010.483209.44570HepG2SF3B4
SP140LENSG00000185404.12476.52880379.491200.328402.270701.67830HepG2SMN1
SP140LENSG00000185404.121556.56490601.299201.3721052.1466050.68760HepG2SRFBP1
SP140LENSG00000185404.12800.14020370.318801.1114013.6541012.77550HepG2SRSF1
SP140LENSG00000185404.12681.42410520.480400.388602.014601.46980HepG2SRSF5
SP140LENSG00000185404.12461.57250301.255700.615505.774805.02870HepG2SRSF9
SP140LENSG00000185404.121087.43000522.050801.0586026.8996025.67020HepG2SSB
SP140LENSG00000185404.12578.18070355.511700.701504.558603.72270HepG2SUPV3L1
SP140LENSG00000185404.12506.52150332.797800.605905.247504.51640HepG2TAF15
SP140LENSG00000185404.12710.35200355.037701.000507.433306.68580HepG2TIAL1
SP140LENSG00000185404.121018.45820449.258301.1807017.5030015.86900HepG2U2AF1
SP140LENSG00000185404.12486.75590325.525200.580302.692201.70150HepG2UPF2
SP140LENSG00000185404.12824.16800582.952400.499505.732004.92100HepG2UTP3
SP140LENSG00000185404.12565.98040349.962500.693504.807903.86150HepG2XRN2
SP140LENSG00000185404.12632.30780425.118600.572706.645605.67890HepG2ZC3H8
SP140LENSG00000185404.12766.898001043.35010-0.444105.210204.47160K562AGGF1
SP140LENSG00000185404.12735.681801085.65840-0.561403.486202.74960K562AKAP8L
SP140LENSG00000185404.12923.638001139.12700-0.302502.613901.72750K562ATP5C1
SP140LENSG00000185404.12793.98010540.741700.554104.375603.27090K562BOP1
SP140LENSG00000185404.12727.28680574.939500.339002.359601.62950K562CPSF6
SP140LENSG00000185404.12969.050201168.21290-0.269702.337601.54220K562DKC1
SP140LENSG00000185404.12420.72160276.920200.603303.882702.78780K562EFTUD2
SP140LENSG00000185404.12735.48040455.271300.691908.916907.73830K562EIF2S2
SP140LENSG00000185404.12360.49780235.873100.611902.433401.49490K562EIF3A
SP140LENSG00000185404.12515.39500296.536000.797405.993204.38430K562EIF3D
SP140LENSG00000185404.12481.77730322.648200.578303.640202.31950K562FKBP4
SP140LENSG00000185404.12746.64870585.033800.351802.090201.34160K562FMR1
SP140LENSG00000185404.12714.30490495.889100.526403.771102.68930K562FTO
SP140LENSG00000185404.12654.98680371.557800.817808.805707.79110K562HNRNPC
SP140LENSG00000185404.121135.74800658.907600.785409.679508.21710K562HSPD1
SP140LENSG00000185404.12989.258301290.68630-0.383703.549202.50030K562MBNL1
SP140LENSG00000185404.12644.03230904.67920-0.490302.792901.90460K562NAA15
SP140LENSG00000185404.12778.44650623.880700.319203.016802.24140K562NSUN2
SP140LENSG00000185404.12926.67080636.602600.541604.114303.09900K562PCBP3
SP140LENSG00000185404.12759.51240488.296600.637206.870505.61610K562POLR2G
SP140LENSG00000185404.12374.65950269.474200.475302.362401.66690K562PRPF8
SP140LENSG00000185404.12790.529701076.63740-0.445603.224702.64610K562PUS1
SP140LENSG00000185404.12746.940601049.05230-0.490005.460804.65250K562RBM15
SP140LENSG00000185404.12459.15680274.517700.742005.115404.00200K562RPS19
SP140LENSG00000185404.12726.55170522.099600.476602.919001.91860K562SF3B1
SP140LENSG00000185404.12361.66140464.59850-0.361301.948101.34240K562SRSF1
SP140LENSG00000185404.12431.24200260.959100.724604.869703.49000K562SUPV3L1
SP140LENSG00000185404.12357.34340470.23730-0.396102.167101.53580K562TARDBP
SP140LENSG00000185404.12449.59710320.427500.488502.690101.76890K562TIAL1
SP140LENSG00000185404.12404.06340276.168200.548903.195502.09690K562UCHL5
SP140LENSG00000185404.12885.60310661.513300.420804.782803.86460K562UPF1
SP140LENSG00000185404.12798.19320566.037000.495704.543403.40940K562WDR3
SP140LENSG00000185404.121036.24700759.908300.447404.029702.95470K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SP140L is not available on ENCORE database.





9 RBPs can affect the splicing of SP140L :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESP140LENSG00000185404.12chr2+231254633231254738231253273231253348231256801231256944-0.458000.000000.00000excludedHepG2U2AF1
SESP140LENSG00000185404.12chr2+2311934712311935462311919842311920162312225192312226820.367000.000180.01997includedHepG2TBRG4
SESP140LENSG00000185404.12chr2+231265026231265128231264841231264957231265669231265768-0.251000.009290.08615excludedHepG2U2AF2
SESP140LENSG00000185404.12chr2+231254633231254738231253273231253348231256801231256944-0.250000.000070.00154excludedHepG2U2AF2
SESP140LENSG00000185404.12chr2+231193471231193546231191984231192016231222519231222682-0.330000.005930.07086excludedK562PUS1
SESP140LENSG00000185404.12chr2+231265048231265128231264841231264957231265669231265768-0.287000.000360.03161excludedHepG2IGF2BP3
SESP140LENSG00000185404.12chr2+2312650482312651282312648412312649572312656692312657680.351000.000100.00606includedK562HNRNPU
SESP140LENSG00000185404.12chr2+231254633231254738231253273231253348231256801231256944-0.281000.001950.04651excludedK562AGGF1
SESP140LENSG00000185404.12chr2+231265048231265128231264841231264957231265669231265768-0.177000.000080.00563excludedK562PTBP1
SESP140LENSG00000185404.12chr2+231254633231254738231253273231253348231256801231256944-0.344000.001090.02071excludedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SP140L is not avaliable on ENCORE database.