SEPT6

General Information

Gene Name       : SEPT6
Gene ID             : ENSG00000125354.22
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SEPT6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SEPT6ENSG00000125354.22204.52240.28222.40ENCSR000AEF
HepG2SEPT6ENSG00000125354.2221.8421.1721.51ENCSR985KAT
K562SEPT6ENSG00000125354.2237.4545.0641.26ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SEPT6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SEPT6 RNA is bound by 26 proteins.  







eCLIP assay for SEPT6 is not avaliable on ENCORE database.





26 proteins are bound to SEPT6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX118763281118763413-3'-UTR,CDS,intron-Distal3.0429525.39590K562ZNF800
chrX118763257118763400-3'-UTR,CDS,intron-Distal,intron-Proximal3.0044420.06905K562PUM1
chrX118763133118763249-3'-UTR,intron-Distal,intron-Proximal3.367686.49379K562EFTUD2
chrX118750985118751078-3'-UTR,intron-Distal4.0660821.65496K562HNRNPL
chrX118763183118763282-3'-UTR,CDS,intron-Distal,intron-Proximal3.4832211.36181K562AQR
chrX118763373118763472-3'-UTR,CDS,intron-Distal,intron-Proximal4.165317.98725K562TRA2A
chrX118763194118763249-3'-UTR,intron-Distal,intron-Proximal4.984445.56495HepG2RBM22
chrX118759228118759335-3'-UTR,intron-Distal,intron-Proximal3.519178.27012K562RBFOX2
chrX118763298118763462-3'-UTR,CDS,intron-Distal5.5706110.81699HepG2BCLAF1
chrX118751070118751145-3'-UTR,intron-Distal3.584297.57656HepG2HNRNPL
chrX118759268118759362-3'-UTR,CDS,intron-Distal,intron-Proximal3.136063.74286HepG2QKI
chrX118750943118750975-3'-UTR,intron-Distal4.199064.66841K562HNRNPL
chrX118751080118751096-3'-UTR,intron-Distal3.5796813.26827K562HNRNPL
chrX118753600118753671-3'-UTR,intron-Distal5.182648.98076K562HNRNPK
chrX118763288118763472-3'-UTR,CDS,intron-Distal,intron-Proximal3.4893018.95707K562UCHL5
chrX118751029118751070-3'-UTR,intron-Distal4.055127.41599HepG2HNRNPL
chrX118759298118759336-3'-UTR,intron-Distal3.416744.06757K562UCHL5
chrX118763295118763472-3'-UTR,CDS,intron-Distal,intron-Proximal3.1372425.13398K562ZNF622
chrX118750986118751073-3'-UTR,intron-Distal4.1319732.43582K562AGGF1
chrX118752049118752109-3'-UTR,intron-Distal3.339694.30200K562LIN28B
chrX118763295118763391-3'-UTR,CDS,intron-Distal3.708487.44851HepG2GRWD1
chrX118753514118753600-3'-UTR,intron-Distal5.6202012.98267K562HNRNPK
chrX118759257118759335-3'-UTR,intron-Distal,intron-Proximal4.4506514.51547HepG2RBFOX2
chrX118753692118753769-3'-UTR,intron-Distal4.590615.27483K562HNRNPK
chrX118809593118809632-5'-UTR,CDS,intron-Distal,intron-Proximal3.999723.16051HepG2PPIG
chrX118827038118827142-5'-UTR,CDS,intron-Distal,intron-Proximal5.477994.97000K562DDX3X
chrX118809559118809626-5'-UTR,CDS,intron-Distal3.473958.10543K562UCHL5
chrX118797555118797640-5'-UTR,CDS,intron-Distal3.014046.86941K562UCHL5
chrX118809514118809593-5'-UTR,CDS,intron-Distal,intron-Proximal4.466164.84481HepG2PPIG
chrX118809591118809633-5'-UTR,CDS,intron-Distal,intron-Proximal3.275873.75245K562BUD13
chrX118797489118797555-CDS,intron-Distal3.061454.63145K562BUD13
chrX118783899118783920-CDS,intron-Distal,intron-Proximal3.183585.71803K562UCHL5
chrX118774710118774750-CDS,intron-Distal3.840888.13606K562UCHL5
chrX118786946118787004-CDS,intron-Distal,intron-Proximal3.788643.34184HepG2GRWD1
chrX118771049118771155-CDS,intron-Distal3.419635.89284K562RBM15
chrX118786817118786880-CDS,intron-Distal3.811935.84565K562ZNF800
chrX118774653118774710-CDS,intron-Distal,intron-Proximal3.588618.38234K562UCHL5
chrX118767325118767373-CDS,intron-Distal3.855218.37042K562ZNF622
chrX118767399118767449-CDS,intron-Distal,intron-Proximal3.233824.86973K562UCHL5
chrX118767409118767433-CDS,intron-Distal,intron-Proximal3.673813.66187K562ZNF622
chrX118771048118771153-CDS,intron-Distal3.4704413.10795K562ZNF622
chrX118767321118767383-CDS,intron-Distal,intron-Proximal3.265336.93682K562UCHL5
chrX118780977118781026-intron-Distal4.179996.34856K562DROSHA
chrX118797238118797367-intron-Distal,intron-Proximal5.100584.24111K562EFTUD2
chrX118755347118755390-intron-Distal6.1499016.68946K562AGGF1
chrX118780659118780709-intron-Distal5.872718.47410K562DROSHA
chrX118755334118755413-intron-Distal4.555895.04227HepG2HNRNPL
chrX118761392118761472-intron-Distal5.204627.91254K562RBFOX2
chrX118826254118826337-intron-Distal3.278413.44195K562TARDBP
chrX118754854118754936-intron-Distal5.518457.03699K562GTF2F1
chrX118769326118769409-intron-Distal4.399073.55787K562PTBP1
chrX118755351118755440-intron-Distal4.244549.36782K562HNRNPL
chrX118755390118755438-intron-Distal3.6065610.64662K562AGGF1
chrX118771428118771502-intron-Distal4.193453.08314K562TARDBP
chrX118757210118757309-intron-Distal4.169853.14791K562HNRNPL
chrX118754870118754924-intron-Distal3.166874.56739K562AGGF1
chrX118771439118771566-intron-Distal6.8869225.93204K562EIF4G2
chrX118780489118780609-intron-Distal5.0190311.00437K562DROSHA
chrX118754130118754217-intron-Distal3.863375.63970K562TARDBP
chrX118780724118780733-intron-Distal7.3085535.39987K562DGCR8
chrX118780733118780754-intron-Distal7.4221438.52734K562DGCR8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SEPT6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SEPT6 is not available on ENCORE database.

  • 102 RBPs can affect the levels of SEPT6.  








The Knockdown/knockout RNA-Seq assay for SEPT6 is not available on ENCORE database.





102 RBPs can affect the gene expression of SEPT6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SEPT6ENSG00000125354.18663.391101040.86260-0.6498011.9567010.88250HepG2ACO1
SEPT6ENSG00000125354.18965.670501477.81730-0.613905.170804.47260HepG2AKAP1
SEPT6ENSG00000125354.18874.377701045.70780-0.258202.327201.61670HepG2AKAP8L
SEPT6ENSG00000125354.18558.65470895.62640-0.680905.194003.90500HepG2BCCIP
SEPT6ENSG00000125354.18330.948101649.47220-2.3173075.1392072.98440HepG2BOP1
SEPT6ENSG00000125354.181619.329801298.086700.318902.833501.58540HepG2BUD13
SEPT6ENSG00000125354.18664.035601040.58220-0.6481012.4906011.28320HepG2CKAP4
SEPT6ENSG00000125354.18640.84540904.33000-0.496902.377101.67140HepG2CNOT7
SEPT6ENSG00000125354.18692.91120939.24900-0.438804.695503.37230HepG2YBX3
SEPT6ENSG00000125354.181195.037001607.93300-0.428207.640306.49730HepG2DAZAP1
SEPT6ENSG00000125354.181204.69950962.623800.323504.221803.21620HepG2DDX19B
SEPT6ENSG00000125354.18755.38360940.56230-0.316302.648701.51780HepG2DDX1
SEPT6ENSG00000125354.181536.099401018.023200.593407.165806.12510HepG2DDX21
SEPT6ENSG00000125354.18914.053901415.61590-0.631106.173805.27410HepG2DDX3X
SEPT6ENSG00000125354.18930.132201216.09340-0.386702.343201.77070HepG2DDX6
SEPT6ENSG00000125354.181421.03710995.809400.512908.430407.37490HepG2DKC1
SEPT6ENSG00000125354.18858.287101291.86990-0.589904.886004.04010HepG2EIF4A3
SEPT6ENSG00000125354.181176.281701586.46220-0.431606.326705.15160HepG2EIF4G1
SEPT6ENSG00000125354.181110.913301707.49050-0.6201013.2975012.14320HepG2ETF1
SEPT6ENSG00000125354.18668.232901017.06060-0.606007.039305.71200HepG2EWSR1
SEPT6ENSG00000125354.18935.899001209.16330-0.369602.321901.71020HepG2G3BP1
SEPT6ENSG00000125354.18809.74900993.69290-0.295302.884701.88920HepG2HDGF
SEPT6ENSG00000125354.181229.48650931.111600.400903.283102.58740HepG2HNRNPA1
SEPT6ENSG00000125354.18853.350101224.47670-0.521004.824303.92180HepG2HNRNPK
SEPT6ENSG00000125354.181138.979701638.17190-0.524305.049404.22450HepG2HNRNPLL
SEPT6ENSG00000125354.18929.516801229.07450-0.403002.812802.13270HepG2IGF2BP2
SEPT6ENSG00000125354.18891.111801050.92680-0.238002.530101.82560HepG2ILF2
SEPT6ENSG00000125354.181719.933902204.66280-0.358202.155001.42970HepG2LARP4
SEPT6ENSG00000125354.18768.622901013.51980-0.399002.862701.62850HepG2LIN28B
SEPT6ENSG00000125354.18875.144801303.97070-0.575305.146704.25960HepG2MAGOH
SEPT6ENSG00000125354.18794.421501311.25700-0.723006.975406.00790HepG2MATR3
SEPT6ENSG00000125354.181032.659401342.13490-0.378202.496901.89340HepG2NCBP2
SEPT6ENSG00000125354.181064.364701594.43160-0.583008.964807.61570HepG2NOL12
SEPT6ENSG00000125354.181193.48700808.558200.561702.561301.51340HepG2NONO
SEPT6ENSG00000125354.18555.77780826.49170-0.572502.762501.87500HepG2PABPC1
SEPT6ENSG00000125354.18952.782601195.21450-0.327101.975001.35610HepG2PABPC4
SEPT6ENSG00000125354.18449.35340679.34160-0.596304.188703.21900HepG2PRPF8
SEPT6ENSG00000125354.181039.085401615.79500-0.6369016.2523015.05940HepG2PUM1
SEPT6ENSG00000125354.18960.388101614.58250-0.7495013.2102011.81100HepG2PUM2
SEPT6ENSG00000125354.181006.850701380.71210-0.455605.784304.92840HepG2QKI
SEPT6ENSG00000125354.18350.176601168.05040-1.7379018.9347017.25070HepG2RAVER1
SEPT6ENSG00000125354.18849.132301427.14320-0.7491014.1406013.15270HepG2RBM22
SEPT6ENSG00000125354.181034.701001253.03190-0.276202.155601.55530HepG2RBM25
SEPT6ENSG00000125354.18813.957101163.80250-0.515804.286203.03520HepG2RBM27
SEPT6ENSG00000125354.181076.376301392.32840-0.371302.956502.25370HepG2RPLP0
SEPT6ENSG00000125354.18753.041501147.35510-0.607503.766002.66460HepG2RPS10
SEPT6ENSG00000125354.18763.292601073.36020-0.491803.945102.99740HepG2RPS2
SEPT6ENSG00000125354.18745.808401095.63990-0.554904.833803.40190HepG2RPS5
SEPT6ENSG00000125354.18416.04040672.01400-0.691804.978503.95820HepG2RRP9
SEPT6ENSG00000125354.18850.186901270.73880-0.579803.505501.78420HepG2RTF1
SEPT6ENSG00000125354.18994.999301552.35150-0.641705.299404.34870HepG2SF3A3
SEPT6ENSG00000125354.18666.457501621.46890-1.2827026.8313024.90750HepG2SF3B1
SEPT6ENSG00000125354.18759.125101327.28390-0.8061016.5877015.32480HepG2SF3B4
SEPT6ENSG00000125354.18920.604301068.47970-0.214902.070401.50180HepG2SMN1
SEPT6ENSG00000125354.18669.724501190.89110-0.830407.464205.84170HepG2SMNDC1
SEPT6ENSG00000125354.181137.022501804.16770-0.666104.601303.58390HepG2SNRNP70
SEPT6ENSG00000125354.181050.072901611.90070-0.6183013.9035013.00980HepG2SRFBP1
SEPT6ENSG00000125354.181120.692401385.34880-0.305903.469902.95590HepG2SRSF1
SEPT6ENSG00000125354.181058.844401744.69960-0.720506.749805.13610HepG2SRSF3
SEPT6ENSG00000125354.181157.370301502.88320-0.376904.849904.05900HepG2SRSF5
SEPT6ENSG00000125354.181040.662501269.93180-0.287202.791402.09320HepG2SRSF7
SEPT6ENSG00000125354.181850.524301399.502500.402906.848306.11020HepG2SSB
SEPT6ENSG00000125354.18589.70640789.68820-0.421302.293601.30650HepG2STIP1
SEPT6ENSG00000125354.181274.523101709.13910-0.423307.367906.43400HepG2SUCLG1
SEPT6ENSG00000125354.18650.07670876.61580-0.431302.449501.80790HepG2SUPV3L1
SEPT6ENSG00000125354.181133.788601487.08130-0.391303.690502.66660HepG2TUFM
SEPT6ENSG00000125354.181035.659801496.55720-0.531105.239704.39060HepG2U2AF1
SEPT6ENSG00000125354.18771.940001995.04190-1.369903.983502.78710HepG2U2AF2
SEPT6ENSG00000125354.181063.529601574.10770-0.565704.102403.07320HepG2UBE2L3
SEPT6ENSG00000125354.18309.87850517.85310-0.740805.824404.71270HepG2UCHL5
SEPT6ENSG00000125354.181064.857601376.70200-0.370605.147504.24110HepG2UPF1
SEPT6ENSG00000125354.18773.437401329.14610-0.7811017.1473015.84630HepG2UTP3
SEPT6ENSG00000125354.18572.58140813.18090-0.506102.863401.74400HepG2XPO5
SEPT6ENSG00000125354.18878.199301284.53260-0.548603.521502.32600HepG2XRCC6
SEPT6ENSG00000125354.181080.046801320.62060-0.290103.641602.88860HepG2ZC3H8
SEPT6ENSG00000125354.181150.867101514.10360-0.395707.030906.26360HepG2ZNF622
SEPT6ENSG00000125354.184141.311105672.33940-0.453905.716104.75750K562AKAP8L
SEPT6ENSG00000125354.182704.917403430.17970-0.342703.856202.35890K562APOBEC3C
SEPT6ENSG00000125354.181659.123402735.12180-0.7212010.018809.00800K562AQR
SEPT6ENSG00000125354.181848.922102436.00660-0.397803.939602.40110K562CIRBP
SEPT6ENSG00000125354.183021.277003660.42000-0.276903.955002.62090K562CPEB4
SEPT6ENSG00000125354.182869.902503787.41210-0.400208.435007.37830K562DDX47
SEPT6ENSG00000125354.181023.821601579.03730-0.625105.186303.39440K562EEF2
SEPT6ENSG00000125354.181050.693601525.58270-0.538005.610404.28430K562EFTUD2
SEPT6ENSG00000125354.183048.218801970.962700.6290011.173309.87280K562EIF2S2
SEPT6ENSG00000125354.181189.114401596.03770-0.424605.412404.31310K562EIF3G
SEPT6ENSG00000125354.181538.807501979.74350-0.363503.403602.49720K562EIF4A3
SEPT6ENSG00000125354.181006.115602058.84590-1.0330032.4709030.52830K562FXR1
SEPT6ENSG00000125354.181486.273202053.50810-0.466403.947802.82160K562HNRNPM
SEPT6ENSG00000125354.184256.903303385.166000.330502.918502.10220K562HSPD1
SEPT6ENSG00000125354.181642.761902388.72220-0.540107.728106.29540K562MAGOH
SEPT6ENSG00000125354.185689.376306743.49960-0.245202.343301.51720K562MBNL1
SEPT6ENSG00000125354.183367.777403007.505500.163102.590901.86550K562NSUN2
SEPT6ENSG00000125354.181319.502202125.38800-0.6877010.541108.57380K562PCBP2
SEPT6ENSG00000125354.18742.971501484.57090-0.9987015.8517014.03460K562PRPF8
SEPT6ENSG00000125354.181108.405202320.78640-1.0661027.6342025.63110K562PTBP1
SEPT6ENSG00000125354.183242.402904241.50470-0.387505.010503.91390K562PUF60
SEPT6ENSG00000125354.183889.041005625.06530-0.532506.393405.60720K562PUS1
SEPT6ENSG00000125354.184363.509305481.05960-0.329004.713703.96010K562RBM15
SEPT6ENSG00000125354.181422.366402225.40710-0.645809.094907.42970K562RBM22
SEPT6ENSG00000125354.181033.494801512.10780-0.549004.674203.60970K562RPS19
SEPT6ENSG00000125354.181935.648802913.85120-0.590106.863005.19700K562RPS3
SEPT6ENSG00000125354.181407.681202112.97820-0.586008.571707.02240K562SF3B4
SEPT6ENSG00000125354.182163.329603040.43740-0.4910013.7989011.92630K562SRPK2
SEPT6ENSG00000125354.181247.713202275.13410-0.8667018.5128016.70360K562SRSF1
SEPT6ENSG00000125354.182266.317901646.339400.461005.315403.44620K562SSB
SEPT6ENSG00000125354.181579.119101964.05500-0.314703.185902.30510K562SYNCRIP
SEPT6ENSG00000125354.181791.575502302.60630-0.362003.078802.33080K562TARDBP
SEPT6ENSG00000125354.182225.525901771.089600.329402.374601.51290K562TIAL1
SEPT6ENSG00000125354.181051.686902034.47790-0.9520013.0501011.28930K562U2AF2
SEPT6ENSG00000125354.183349.945102728.658700.295802.950602.04760K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SEPT6 is not available on ENCORE database.





15 RBPs can affect the splicing of SEPT6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESEPT6ENSG00000125354.18chrX-1187592971187593421187526751187527491187632801187634710.484000.000000.00015includedK562RBFOX2
SESEPT6ENSG00000125354.18chrX-1187592971187593421187526751187527491187632801187634710.421000.000000.00071includedHepG2HNRNPM
SESEPT6ENSG00000125354.18chrX-118759297118759342118750910118754014118763280118763471-0.428000.003730.07683excludedHepG2HNRNPK
SESEPT6ENSG00000125354.18chrX-1187592971187593421187526751187527491187632801187634710.677000.000000.00000includedHepG2QKI
SESEPT6ENSG00000125354.18chrX-1187592971187593421187526751187527491187632801187634710.452000.000000.00044includedHepG2NCBP2
SESEPT6ENSG00000125354.18chrX-118759297118759342118752675118752749118763280118763471-0.157000.000000.00259excludedK562LARP4
SESEPT6ENSG00000125354.18chrX-1187592971187593421187526751187527491187632801187634710.505000.000080.01780includedK562HNRNPM
SESEPT6ENSG00000125354.18chrX-118759297118759342118749686118750705118763280118763471-0.220000.000200.01926excludedK562HNRNPL
SESEPT6ENSG00000125354.18chrX-1187592971187593421187526751187527491187632801187634710.446000.000030.00703includedHepG2RBFOX2
SESEPT6ENSG00000125354.18chrX-118759297118759342118752675118752749118763280118763471-0.258000.000000.00191excludedK562UPF1
SESEPT6ENSG00000125354.18chrX-118770989118771158118767322118767455118774654118774751-0.080000.001830.03260excludedK562U2AF2
SESEPT6ENSG00000125354.18chrX-118759297118759342118750910118754014118763280118763471-0.210000.001980.06332excludedK562HNRNPU
SESEPT6ENSG00000125354.18chrX-118759297118759342118750910118754014118763280118763471-0.095000.002430.05326excludedK562RBM15
SESEPT6ENSG00000125354.18chrX-118759297118759342118752675118752749118763280118763471-0.155000.000110.00473excludedK562AGGF1
SESEPT6ENSG00000125354.18chrX-1187592971187593421187526751187527491187632801187634710.291000.000370.08058includedHepG2FUBP3
SESEPT6ENSG00000125354.18chrX-118759297118759342118752675118752749118763280118763471-0.249000.000170.01153excludedK562HNRNPK
MXESEPT6ENSG00000125354.18chrX-1187974441187976401188095161188096311187868161187870031188270381188273330.147000.000780.022211includedK562TARDBP
MXESEPT6ENSG00000125354.18chrX-1187974441187976401188095161188096311187868161187870031188270381188273330.169000.000060.005371includedK562IGF2BP2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SEPT6 is not avaliable on ENCORE database.