SEPHS1

General Information

Gene Name       : SEPHS1
Gene ID             : ENSG00000086475.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SEPHS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SEPHS1ENSG00000086475.1458.9558.0958.52ENCSR000AEF
HepG2SEPHS1ENSG00000086475.1482.8196.5489.68ENCSR985KAT
K562SEPHS1ENSG00000086475.1460.1153.7356.92ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SEPHS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SEPHS1 RNA is bound by 6 proteins.  







eCLIP assay for SEPHS1 is not avaliable on ENCORE database.





6 proteins are bound to SEPHS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr101338999613390073-5'-UTR,intron-Distal,intron-Proximal6.376148.97384HepG2DDX3X
chr101339018313390236-5'-UTR,intron-Distal5.0127512.43527HepG2DDX3X
chr101339011313390183-5'-UTR,intron-Distal,intron-Proximal5.9403017.66846HepG2DDX3X
chr101338930513389341-5'-UTR,intron-Distal4.458703.67126HepG2NKRF
chr101336489113364915-CDS,intron-Distal5.390646.37354HepG2LIN28B
chr101336488313364922-CDS,intron-Distal4.214886.87736K562LIN28B
chr101336491513364931-CDS,intron-Distal5.314635.78061HepG2LIN28B
chr101336480013364861-CDS,intron-Distal,intron-Proximal4.080487.29769HepG2PRPF8
chr101336492213364954-CDS,intron-Distal5.172957.65820K562LIN28B
chr101337582913375900-CDS,intron-Distal,intron-Proximal3.393963.93645HepG2PPIG
chr101338991413389958-intron-Distal4.841476.87001HepG2NKRF
chr101338954613389599-intron-Distal3.931698.20482HepG2NKRF
chr101338961713389702-intron-Distal4.0146610.93118HepG2NKRF
chr101338944013389532-intron-Distal,intron-Proximal4.058854.49762HepG2XRN2
chr101338055213380618-intron-Distal,intron-Proximal3.176913.20886K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SEPHS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SEPHS1 is not available on ENCORE database.

  • 111 RBPs can affect the levels of SEPHS1.  








The Knockdown/knockout RNA-Seq assay for SEPHS1 is not available on ENCORE database.





111 RBPs can affect the gene expression of SEPHS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SEPHS1ENSG00000086475.10988.213301144.26940-0.211501.897401.37650HepG2ACO1
SEPHS1ENSG00000086475.10388.90230811.12840-1.0605012.1087010.11980HepG2AKAP8
SEPHS1ENSG00000086475.10925.692501149.62040-0.312603.332502.50010HepG2AKAP8L
SEPHS1ENSG00000086475.10835.594901219.31450-0.545204.723303.70940HepG2ASCC1
SEPHS1ENSG00000086475.101234.230701899.51830-0.6220013.9243012.59380HepG2AUH
SEPHS1ENSG00000086475.10993.673201341.18190-0.432702.644201.73050HepG2BCCIP
SEPHS1ENSG00000086475.10708.128301165.42210-0.718806.712805.38030HepG2BCLAF1
SEPHS1ENSG00000086475.10867.284801379.94300-0.670008.327407.35700HepG2BOP1
SEPHS1ENSG00000086475.10720.105501038.27990-0.527905.367303.68290HepG2BUD13
SEPHS1ENSG00000086475.10795.475501165.11700-0.550606.984405.83040HepG2CALR
SEPHS1ENSG00000086475.10900.091901143.99050-0.345904.512803.70280HepG2CKAP4
SEPHS1ENSG00000086475.10977.298901266.86030-0.374402.752802.06760HepG2CPSF6
SEPHS1ENSG00000086475.10830.920801141.25500-0.457804.228702.87750HepG2CPSF7
SEPHS1ENSG00000086475.10918.539301107.44200-0.269802.237701.32400HepG2YBX3
SEPHS1ENSG00000086475.101309.797801639.50750-0.323903.749703.02400HepG2CELF1
SEPHS1ENSG00000086475.10825.121301108.96920-0.426504.721403.22570HepG2DDX1
SEPHS1ENSG00000086475.10788.45120976.78770-0.309002.124401.52160HepG2DDX21
SEPHS1ENSG00000086475.101089.029501411.62820-0.374302.559701.95600HepG2DDX3X
SEPHS1ENSG00000086475.10601.908501318.63950-1.1314014.7219013.12610HepG2DDX55
SEPHS1ENSG00000086475.10339.196401212.66260-1.8380033.4214031.62000HepG2DDX6
SEPHS1ENSG00000086475.10695.548501048.80470-0.592506.374204.92950HepG2DHX30
SEPHS1ENSG00000086475.10671.799701087.39960-0.6948011.4331010.08240HepG2DNAJC21
SEPHS1ENSG00000086475.10747.731801077.83450-0.527509.312408.19900HepG2DNAJC2
SEPHS1ENSG00000086475.10607.21980899.21820-0.566503.847702.53020HepG2AGO1
SEPHS1ENSG00000086475.10852.662001165.71750-0.451203.362202.71280HepG2EIF2S1
SEPHS1ENSG00000086475.10938.388901288.23340-0.457103.196402.50990HepG2EIF4A3
SEPHS1ENSG00000086475.101247.557401739.17430-0.479308.258706.95560HepG2EIF4G1
SEPHS1ENSG00000086475.10512.85200722.96550-0.495404.675003.11860HepG2FAM120A
SEPHS1ENSG00000086475.101074.192401399.26920-0.381402.333201.62220HepG2FIP1L1
SEPHS1ENSG00000086475.10576.462101097.59600-0.9290010.685408.50980HepG2FKBP4
SEPHS1ENSG00000086475.10618.007001269.03700-1.038005.378003.96840HepG2FTO
SEPHS1ENSG00000086475.10812.952401205.75660-0.568704.790003.92550HepG2G3BP1
SEPHS1ENSG00000086475.10958.94300720.156100.413002.959002.03050HepG2GEMIN5
SEPHS1ENSG00000086475.10670.609601436.07810-1.0986015.6439014.23930HepG2GPKOW
SEPHS1ENSG00000086475.10793.744701092.43140-0.460806.321304.92100HepG2HDGF
SEPHS1ENSG00000086475.10865.336201097.81750-0.343302.561501.93720HepG2HNRNPA1
SEPHS1ENSG00000086475.10977.611101620.10230-0.7288016.2006014.32360HepG2HNRNPA2B1
SEPHS1ENSG00000086475.101008.546701487.41640-0.5605010.229108.96150HepG2HNRNPF
SEPHS1ENSG00000086475.101307.798901605.76310-0.296104.294403.46790HepG2HNRNPL
SEPHS1ENSG00000086475.10721.074901370.47640-0.9265013.0017011.76890HepG2HNRNPLL
SEPHS1ENSG00000086475.10613.078901213.05710-0.9845025.9830024.28080HepG2HNRNPU
SEPHS1ENSG00000086475.101052.359201464.68280-0.477005.782704.77510HepG2IGF2BP1
SEPHS1ENSG00000086475.10882.723101225.61310-0.473503.744202.96950HepG2IGF2BP2
SEPHS1ENSG00000086475.10998.500101239.09550-0.311504.281303.38890HepG2ILF2
SEPHS1ENSG00000086475.10890.994701232.78010-0.468402.877801.85350HepG2KHSRP
SEPHS1ENSG00000086475.10890.828001045.98690-0.231602.249201.32760HepG2KIF1C
SEPHS1ENSG00000086475.10718.431201132.54420-0.656608.128206.80700HepG2MSI2
SEPHS1ENSG00000086475.10807.661101397.72270-0.791306.062904.60130HepG2MTPAP
SEPHS1ENSG00000086475.10745.46020950.98550-0.351302.589101.41500HepG2NAA15
SEPHS1ENSG00000086475.10721.72190989.57280-0.455403.690402.04390HepG2NIP7
SEPHS1ENSG00000086475.101431.644301748.00010-0.288002.785702.01860HepG2NOL12
SEPHS1ENSG00000086475.10874.963701215.19440-0.473904.029303.13080HepG2NSUN2
SEPHS1ENSG00000086475.10384.07640690.40820-0.846105.128803.89000HepG2PABPC1
SEPHS1ENSG00000086475.10665.004101191.84970-0.841809.822308.48080HepG2PABPC4
SEPHS1ENSG00000086475.10636.069301200.70340-0.9166021.3750019.45670HepG2PARN
SEPHS1ENSG00000086475.10894.964201258.31530-0.491607.639206.71030HepG2PCBP1
SEPHS1ENSG00000086475.10771.632401157.63380-0.585203.653102.46980HepG2PCBP2
SEPHS1ENSG00000086475.10746.414701081.94780-0.535607.261306.10860HepG2PPIL4
SEPHS1ENSG00000086475.10766.885701093.73770-0.512207.477606.28200HepG2PRPF4
SEPHS1ENSG00000086475.10755.625301017.33840-0.429102.768601.95940HepG2PRPF8
SEPHS1ENSG00000086475.10822.436201280.36870-0.6386011.7127010.74020HepG2PTBP1
SEPHS1ENSG00000086475.101267.360501668.63710-0.396803.839703.15050HepG2PUF60
SEPHS1ENSG00000086475.102027.779101771.353100.194902.660202.07580HepG2PUM1
SEPHS1ENSG00000086475.101181.816801770.04610-0.582808.910507.74050HepG2PUM2
SEPHS1ENSG00000086475.10693.478901165.50820-0.7490016.4787015.19870HepG2PUS1
SEPHS1ENSG00000086475.10942.673201386.70110-0.556807.954406.97930HepG2QKI
SEPHS1ENSG00000086475.101041.761701432.54440-0.459605.364704.21800HepG2RBM15
SEPHS1ENSG00000086475.101437.429601822.82010-0.342704.060303.46360HepG2RBM22
SEPHS1ENSG00000086475.10809.214801258.50900-0.637108.396907.27190HepG2RBM25
SEPHS1ENSG00000086475.10906.918301602.27920-0.8211012.9244011.64250HepG2RPLP0
SEPHS1ENSG00000086475.10745.261201097.57260-0.558503.251102.22730HepG2RPS10
SEPHS1ENSG00000086475.10507.916201006.36960-0.9865010.803409.40490HepG2RRP9
SEPHS1ENSG00000086475.10899.384601080.27370-0.264402.656002.02190HepG2SAFB2
SEPHS1ENSG00000086475.10605.40960789.89200-0.383702.433801.54930HepG2SERBP1
SEPHS1ENSG00000086475.10714.370101356.49700-0.9251014.1782012.71220HepG2SF3B1
SEPHS1ENSG00000086475.101095.240201333.05450-0.283502.970902.36210HepG2SF3B4
SEPHS1ENSG00000086475.101187.913701600.00620-0.429607.676606.59720HepG2SLBP
SEPHS1ENSG00000086475.10652.660601509.34220-1.2095012.8070011.14260HepG2SNRNP70
SEPHS1ENSG00000086475.101109.389402058.81390-0.8920029.8503028.65930HepG2SRFBP1
SEPHS1ENSG00000086475.101252.806001647.56140-0.395205.722304.86900HepG2SRSF5
SEPHS1ENSG00000086475.10930.051701461.32990-0.6519013.3362012.00630HepG2SRSF7
SEPHS1ENSG00000086475.10585.431401131.97710-0.9513023.7131022.39260HepG2SRSF9
SEPHS1ENSG00000086475.101227.981301787.54800-0.5417011.2823010.38230HepG2SSB
SEPHS1ENSG00000086475.10701.12820944.91120-0.430503.527802.47590HepG2SUPT6H
SEPHS1ENSG00000086475.10657.295701312.71860-0.9979012.0760010.82960HepG2SUPV3L1
SEPHS1ENSG00000086475.10942.988601335.80820-0.502404.856203.93260HepG2TARDBP
SEPHS1ENSG00000086475.10529.06760879.88950-0.733906.194204.79990HepG2TFIP11
SEPHS1ENSG00000086475.10888.001101149.18430-0.372003.553302.61030HepG2TIA1
SEPHS1ENSG00000086475.10659.352201178.66540-0.8380014.6059013.61610HepG2TIAL1
SEPHS1ENSG00000086475.10579.463701189.25140-1.0373027.6958026.14730HepG2TRIM56
SEPHS1ENSG00000086475.101197.342301725.58720-0.527304.373303.30550HepG2UBE2L3
SEPHS1ENSG00000086475.10423.34270775.48600-0.873309.270407.88220HepG2UCHL5
SEPHS1ENSG00000086475.10632.540601176.47000-0.8952021.8879020.29420HepG2UPF1
SEPHS1ENSG00000086475.10829.777601202.13580-0.534803.176202.09930HepG2UPF2
SEPHS1ENSG00000086475.101017.385901292.22650-0.345002.055201.42250HepG2XRN2
SEPHS1ENSG00000086475.10792.484801079.40250-0.445806.593205.62920HepG2ZC3H8
SEPHS1ENSG00000086475.10686.444601293.89170-0.9145027.4579026.18980HepG2ZNF622
SEPHS1ENSG00000086475.10817.134101116.30440-0.450102.598401.34630HepG2ZRANB2
SEPHS1ENSG00000086475.101197.235601023.683900.225801.778201.30300K562AGGF1
SEPHS1ENSG00000086475.10688.98340840.66740-0.287102.409501.51580K562BCLAF1
SEPHS1ENSG00000086475.10537.77250812.03780-0.594604.988403.80290K562BOP1
SEPHS1ENSG00000086475.10625.45670863.41470-0.465104.179503.21350K562CPSF6
SEPHS1ENSG00000086475.101404.058501146.333700.292502.782701.90580K562DKC1
SEPHS1ENSG00000086475.10663.56370878.53200-0.404902.927602.04720K562FMR1
SEPHS1ENSG00000086475.10474.79170744.64730-0.649305.468004.13340K562FTO
SEPHS1ENSG00000086475.101254.15170678.901400.8853018.8425017.37390K562FXR1
SEPHS1ENSG00000086475.10548.20680824.33700-0.588505.526504.40880K562GPKOW
SEPHS1ENSG00000086475.10541.48860841.77180-0.636506.718105.82780K562HNRNPC
SEPHS1ENSG00000086475.10535.39030751.81210-0.489804.014402.60540K562HNRNPF
SEPHS1ENSG00000086475.101210.08290882.765200.454903.278902.25920K562HNRNPM
SEPHS1ENSG00000086475.10801.082301176.73820-0.554807.731806.24660K562HNRNPU
SEPHS1ENSG00000086475.10439.19030703.91140-0.680504.512203.28510K562KRR1
SEPHS1ENSG00000086475.10636.62250804.64980-0.337902.159501.38560K562METAP2
SEPHS1ENSG00000086475.101376.115301855.81910-0.431503.670402.36800K562MSI2
SEPHS1ENSG00000086475.10792.19770981.26670-0.308803.112302.25520K562MTPAP
SEPHS1ENSG00000086475.101236.03200887.661100.477502.884501.98080K562NAA15
SEPHS1ENSG00000086475.10924.986701090.31950-0.237202.491001.77860K562NSUN2
SEPHS1ENSG00000086475.101101.67050734.372300.585005.723204.64280K562PRPF8
SEPHS1ENSG00000086475.10506.07590754.76690-0.576705.072103.79790K562PSIP1
SEPHS1ENSG00000086475.101542.278301979.76540-0.360304.102802.92610K562PUM2
SEPHS1ENSG00000086475.101577.767701056.510300.578506.312105.53050K562PUS1
SEPHS1ENSG00000086475.101358.381701029.280600.400204.321203.59660K562RBM15
SEPHS1ENSG00000086475.10563.03060784.01600-0.477703.051402.02930K562SF3B1
SEPHS1ENSG00000086475.10390.44320534.27790-0.452502.917601.61820K562SLBP
SEPHS1ENSG00000086475.10970.217801288.06690-0.408803.084001.75060K562STAU1
SEPHS1ENSG00000086475.101133.94740771.668200.555206.928805.61460K562SYNCRIP
SEPHS1ENSG00000086475.10441.67140725.94180-0.716906.248804.78780K562TIAL1
SEPHS1ENSG00000086475.10585.82110771.38200-0.397002.766401.82080K562TRIM56
SEPHS1ENSG00000086475.10932.898801255.68710-0.428703.532501.92430K562TRIP6
SEPHS1ENSG00000086475.10555.14460752.62810-0.439102.801701.77600K562UCHL5
SEPHS1ENSG00000086475.10863.790701156.08540-0.420505.762404.76890K562UPF1
SEPHS1ENSG00000086475.10808.42470989.23140-0.291202.097501.33700K562WDR3
SEPHS1ENSG00000086475.101254.452601599.96560-0.351002.340901.55800K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SEPHS1 is not available on ENCORE database.





4 RBPs can affect the splicing of SEPHS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESEPHS1ENSG00000086475.10chr10-133867571338702813380704133808081338999913390280-0.120000.002470.04318excludedK562SRSF1
SESEPHS1ENSG00000086475.10chr10-133782421337835013375816133759711338070413380808-0.088000.000020.00080excludedK562SF3B4
SESEPHS1ENSG00000086475.10chr10-133782421337839713375900133759711338070413380808-0.056000.000650.00852excludedK562AQR
SESEPHS1ENSG00000086475.10chr10-133867571338702813380704133808081338999913390297-0.054000.000550.03871excludedHepG2FTO
A3SSSEPHS1ENSG00000086475.10chr10-1337169713371821133716971337178813375816133759710.077000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SEPHS1 is not avaliable on ENCORE database.