RBX1

General Information

Gene Name       : RBX1
Gene ID             : ENSG00000100387.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: RBX1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RBX1ENSG00000100387.869.5274.5872.05ENCSR000AEF
HepG2RBX1ENSG00000100387.853.5670.7562.16ENCSR985KAT
K562RBX1ENSG00000100387.853.5845.6849.63ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RBX1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RBX1 RNA is bound by 22 proteins.  







eCLIP assay for RBX1 is not avaliable on ENCORE database.





22 proteins are bound to RBX1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr224136859541368671+3'-UTR3.129968.08133K562PABPC4
chr224136859041368645+3'-UTR4.378583.78849HepG2TIAL1
chr224136858941368655+3'-UTR4.6913321.52705HepG2FUBP3
chr224136853341368594+3'-UTR6.1012215.36878HepG2LARP4
chr224136853141368584+3'-UTR3.127284.01705HepG2FUBP3
chr224136858941368654+3'-UTR5.5456919.58757HepG2SUB1
chr224136853441368652+3'-UTR3.945915.89818K562APOBEC3C
chr224136855641368647+3'-UTR5.227478.86741K562NOLC1
chr224136859241368655+3'-UTR3.750955.68843K562DDX6
chr224136851641368650+3'-UTR3.022324.80571K562TIA1
chr224136859441368652+3'-UTR4.7220613.09540HepG2LARP4
chr224134739441347470+5'-UTR,CDS,intron-Distal3.490494.36276HepG2LARP4
chr224134737941347477+5'-UTR,CDS,intron-Distal5.158705.65617K562DDX55
chr224134955441349654+3'-UTR,CDS,intron-Proximal3.384185.15500HepG2BCLAF1
chr224134958641349686+3'-UTR,CDS,intron-Proximal3.476198.39123HepG2PRPF8
chr224134954041349601+3'-UTR,CDS,intron-Proximal3.477617.55775HepG2U2AF2
chr224136004941360125+3'-UTR,CDS,intron-Proximal3.415053.68647K562SND1
chr224134955341349626+3'-UTR,CDS,intron-Proximal4.745974.89487HepG2LARP4
chr224135999741360052+3'-UTR,CDS,intron-Proximal3.844743.50006HepG2SF3B4
chr224135385641353886+intron-Distal4.495275.18400HepG2ILF3
chr224134781841347912+intron-Distal4.868866.41765K562GTF2F1
chr224135164141351744+intron-Distal3.078323.74286HepG2QKI
chr224134781641347882+intron-Distal4.458495.01722K562CSTF2T
chr224135414241354196+intron-Distal3.232793.09748HepG2ILF3
chr224134781141347885+intron-Distal4.018993.30336K562EWSR1
chr224135384241353856+intron-Distal4.372844.54503HepG2ILF3
chr224134781241347895+intron-Distal4.129083.40229HepG2CSTF2T
chr224134781841347897+intron-Distal4.083186.89283HepG2PRPF4
chr224134781641347879+intron-Distal4.815926.97401HepG2GTF2F1
chr224134781741347886+intron-Distal4.127677.98928HepG2FAM120A
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RBX1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RBX1 is not available on ENCORE database.

  • 84 RBPs can affect the levels of RBX1.  








The Knockdown/knockout RNA-Seq assay for RBX1 is not available on ENCORE database.





84 RBPs can affect the gene expression of RBX1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RBX1ENSG00000100387.8658.82880528.564000.317702.639902.04330HepG2ACO1
RBX1ENSG00000100387.8472.73470667.16500-0.497002.845502.06220HepG2DDX55
RBX1ENSG00000100387.8624.868901010.91160-0.694006.546505.65760HepG2EIF2S1
RBX1ENSG00000100387.8776.961101117.15370-0.523903.792703.04930HepG2EIF4A3
RBX1ENSG00000100387.8781.336901087.74870-0.477302.684102.00550HepG2EIF4B
RBX1ENSG00000100387.8953.092101180.80370-0.309103.140102.50610HepG2ETF1
RBX1ENSG00000100387.8838.041301127.22920-0.427703.108902.37530HepG2FXR1
RBX1ENSG00000100387.8791.504301045.63460-0.401702.577701.93500HepG2G3BP1
RBX1ENSG00000100387.8676.248201110.12190-0.715107.474606.00090HepG2G3BP2
RBX1ENSG00000100387.8249.64920525.02130-1.072509.596408.36960HepG2HNRNPC
RBX1ENSG00000100387.8401.13860498.48410-0.313402.149501.51090HepG2HNRNPF
RBX1ENSG00000100387.8758.17110947.13020-0.321003.680202.91050HepG2HNRNPL
RBX1ENSG00000100387.8172.57250250.56540-0.538002.176601.61170HepG2HNRNPLL
RBX1ENSG00000100387.8669.541001062.85200-0.666706.359805.37430HepG2IGF2BP2
RBX1ENSG00000100387.8622.629701069.07130-0.779906.427204.83080HepG2KHSRP
RBX1ENSG00000100387.8626.851601127.62300-0.847109.675908.46710HepG2MAGOH
RBX1ENSG00000100387.8646.442301133.92310-0.810708.082407.05070HepG2MATR3
RBX1ENSG00000100387.8747.494001160.62440-0.634805.763204.86440HepG2NCBP2
RBX1ENSG00000100387.8792.514601030.99510-0.379503.729902.84190HepG2NOL12
RBX1ENSG00000100387.8230.25510612.63000-1.411809.291207.25530HepG2NONO
RBX1ENSG00000100387.8585.593501033.57050-0.819708.871907.59780HepG2PABPC4
RBX1ENSG00000100387.8365.15790919.46990-1.3323034.1024032.37910HepG2PCBP1
RBX1ENSG00000100387.8334.82670465.18770-0.474403.628202.79560HepG2PPIL4
RBX1ENSG00000100387.8628.12400935.58420-0.574807.878307.05120HepG2PTBP1
RBX1ENSG00000100387.8596.72690984.16340-0.721809.027608.03450HepG2PUF60
RBX1ENSG00000100387.8598.731301044.71920-0.8031018.4220017.16670HepG2PUM1
RBX1ENSG00000100387.8693.315801043.96460-0.590507.378006.30240HepG2PUM2
RBX1ENSG00000100387.8768.422101013.28380-0.399103.854503.13360HepG2QKI
RBX1ENSG00000100387.8664.98960919.61150-0.467704.314103.48700HepG2RBM25
RBX1ENSG00000100387.8662.549401041.22440-0.6522010.320209.39720HepG2NELFE
RBX1ENSG00000100387.8585.06290969.74270-0.7290012.2171011.06150HepG2RECQL
RBX1ENSG00000100387.8184.12500330.84190-0.845506.308105.42120HepG2RPS19
RBX1ENSG00000100387.8501.44540660.42300-0.397302.324701.58800HepG2RPS2
RBX1ENSG00000100387.8319.04310541.46250-0.763105.059903.97950HepG2RPS3A
RBX1ENSG00000100387.8340.14590464.48150-0.449503.125802.44940HepG2SAFB2
RBX1ENSG00000100387.8302.90180509.88010-0.751305.208503.41040HepG2SART3
RBX1ENSG00000100387.8648.22420974.08330-0.587608.376007.43360HepG2SF3B4
RBX1ENSG00000100387.8678.02630943.63110-0.476906.701205.68470HepG2SLBP
RBX1ENSG00000100387.81299.019801114.733200.220602.319801.84780HepG2SRFBP1
RBX1ENSG00000100387.8707.96320971.70160-0.456805.681004.83060HepG2SRSF5
RBX1ENSG00000100387.8542.01570827.15240-0.609808.924808.03440HepG2SRSF9
RBX1ENSG00000100387.8785.48250967.88240-0.301302.337401.85720HepG2SSB
RBX1ENSG00000100387.8850.829701105.10640-0.377205.084004.28400HepG2SUCLG1
RBX1ENSG00000100387.8694.91450913.84940-0.395103.729303.09460HepG2TAF15
RBX1ENSG00000100387.8566.12940839.72630-0.568806.107404.87150HepG2TIA1
RBX1ENSG00000100387.8338.38870506.88870-0.583003.466402.92000HepG2TIAL1
RBX1ENSG00000100387.8358.48870511.30900-0.512304.077403.41960HepG2TRIM56
RBX1ENSG00000100387.8648.47030961.46360-0.568206.124404.75430HepG2TUFM
RBX1ENSG00000100387.8691.000901017.67930-0.558504.018202.99860HepG2UBE2L3
RBX1ENSG00000100387.8584.43040392.336100.574804.168103.23620HepG2UCHL5
RBX1ENSG00000100387.8821.50470608.162600.433702.245101.34760HepG2UPF2
RBX1ENSG00000100387.8430.86800605.44560-0.490802.492401.48940HepG2XRCC6
RBX1ENSG00000100387.8490.09120376.277600.381203.019002.45520HepG2ZNF622
RBX1ENSG00000100387.8354.18770549.96700-0.634803.857502.30440HepG2ZRANB2
RBX1ENSG00000100387.8754.37870474.778200.667908.915907.97220K562AGGF1
RBX1ENSG00000100387.8706.50470521.711200.437303.316502.21850K562AKAP8
RBX1ENSG00000100387.8779.68510494.028700.658206.705705.65580K562AKAP8L
RBX1ENSG00000100387.8754.087501221.60690-0.696003.930903.25510K562AQR
RBX1ENSG00000100387.8652.26210518.355800.331402.479201.61820K562ATP5C1
RBX1ENSG00000100387.8510.88440666.98460-0.384703.201702.17060K562BCLAF1
RBX1ENSG00000100387.8156.71220247.69230-0.660403.470602.26070K562CCAR1
RBX1ENSG00000100387.8451.84640587.01820-0.377602.577401.50980K562CPEB4
RBX1ENSG00000100387.8215.62220316.63770-0.554303.047602.22610K562CPSF6
RBX1ENSG00000100387.8190.38810277.26670-0.542302.698601.38730K562DHX30
RBX1ENSG00000100387.8694.30560531.607600.385103.347502.37280K562DKC1
RBX1ENSG00000100387.8130.74860251.95590-0.946403.985902.75430K562EIF3A
RBX1ENSG00000100387.8632.07860431.703400.550004.398403.31290K562FIP1L1
RBX1ENSG00000100387.8231.46650322.16110-0.477002.186801.42350K562FMR1
RBX1ENSG00000100387.8133.43200482.68840-1.8550027.1547025.36890K562HNRNPC
RBX1ENSG00000100387.8281.16850431.07740-0.616504.282402.82580K562HNRNPF
RBX1ENSG00000100387.8492.66190355.110100.472202.578201.68340K562HNRNPM
RBX1ENSG00000100387.8717.56050524.286400.452603.242702.34230K562KIF1C
RBX1ENSG00000100387.8665.59520411.678300.693004.591503.36550K562NAA15
RBX1ENSG00000100387.8401.80620515.12850-0.358402.818902.06630K562NSUN2
RBX1ENSG00000100387.8566.13120348.274600.700802.740801.75700K562PABPN1
RBX1ENSG00000100387.8264.13220469.16860-0.828804.093603.08020K562PCBP3
RBX1ENSG00000100387.8858.847401073.83140-0.322302.846101.38530K562PNPT1
RBX1ENSG00000100387.8225.55660359.89670-0.674102.697901.90850K562POLR2G
RBX1ENSG00000100387.8672.74660490.108900.456903.295102.38610K562PPIG
RBX1ENSG00000100387.8785.64660531.239400.564403.948903.05430K562PRPF8
RBX1ENSG00000100387.8289.04890432.79080-0.582404.224103.07230K562PSIP1
RBX1ENSG00000100387.81010.372901188.24840-0.233902.223101.36010K562PUM2
RBX1ENSG00000100387.8827.19370489.938000.755508.092007.21050K562PUS1
RBX1ENSG00000100387.8789.26130477.373200.725309.553708.47580K562RBM15
RBX1ENSG00000100387.8283.77580394.91380-0.476802.852701.84660K562RCC2
RBX1ENSG00000100387.8571.20190841.92660-0.559704.834503.34370K562NELFE
RBX1ENSG00000100387.8177.97220272.85280-0.616503.314501.91770K562SLBP
RBX1ENSG00000100387.8262.59680374.36270-0.511602.687901.68280K562SRFBP1
RBX1ENSG00000100387.8248.46180416.26650-0.744505.007303.71470K562TIAL1
RBX1ENSG00000100387.8267.83060442.28320-0.723605.358603.93840K562TRIM56
RBX1ENSG00000100387.8420.79890546.19990-0.376302.879502.14620K562UPF1
RBX1ENSG00000100387.8347.31530554.27790-0.674402.631301.46060K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RBX1 is not available on ENCORE database.





17 RBPs can affect the splicing of RBX1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERBX1ENSG00000100387.8chr22+4136005041360238413473624134748041368479413693130.205000.002750.07844includedK562PRPF8
SERBX1ENSG00000100387.8chr22+413495584134963741347362413474804136380241363888-0.069000.000040.00306excludedK562PRPF8
SERBX1ENSG00000100387.8chr22+413638024136388841360050413601214136847941369313-0.116000.000000.00003excludedHepG2U2AF1
SERBX1ENSG00000100387.8chr22+4136005041360121413473624134748041363802413638880.083000.004390.04793includedHepG2U2AF2
SERBX1ENSG00000100387.8chr22+413638024136388841360050413601214136847941369313-0.054000.005260.05528excludedHepG2U2AF2
SERBX1ENSG00000100387.8chr22+413495584134963741347350413474804136380241363888-0.058000.000070.00123excludedK562AQR
SERBX1ENSG00000100387.8chr22+413495584134963741347362413474804136380241363888-0.061000.003480.04702excludedK562PUS1
SERBX1ENSG00000100387.8chr22+413495584134963741347362413474804136380241363888-0.127000.000460.06651excludedHepG2HNRNPA1
SERBX1ENSG00000100387.8chr22+413495584134963741347362413474804136380241363888-0.053000.000890.04708excludedK562EFTUD2
SERBX1ENSG00000100387.8chr22+413600504136012141347362413474804136380241363888-0.058000.000020.00173excludedHepG2SF3B4
SERBX1ENSG00000100387.8chr22+413600504136012141347362413474804136380241363888-0.066000.000150.00820excludedK562UTP18
SERBX1ENSG00000100387.8chr22+413638024136388841360050413601214136847941369313-0.064000.000000.00007excludedK562U2AF2
SERBX1ENSG00000100387.8chr22+413495584134963741347362413474804136380241363888-0.053000.001310.04602excludedK562HNRNPU
SERBX1ENSG00000100387.8chr22+413495584134963741347362413474804136380241363888-0.105000.001740.06537excludedHepG2HNRNPU
SERBX1ENSG00000100387.8chr22+4135129041351450413495584134963741360050413601210.114000.000000.00000includedHepG2HNRNPC
SERBX1ENSG00000100387.8chr22+4135129041351450413495584134963741360050413601210.325000.000000.00000includedK562HNRNPC
A5SSRBX1ENSG00000100387.8chr22+413600504136023841360050413601214136847941369313-0.259000.001070.07803shorterHepG2U2AF1
MXERBX1ENSG00000100387.8chr22+41349558413496374136380241363888413473624134748041368479413693130.160000.000100.003001includedHepG2U2AF1
MXERBX1ENSG00000100387.8chr22+41349558413496374136005041360121413473624134748041363802413638880.142000.000510.012351includedHepG2U2AF1
MXERBX1ENSG00000100387.8chr22+41360050413602384136380241363888413495584134963741368479413693130.152000.000080.002541includedHepG2U2AF1
MXERBX1ENSG00000100387.8chr22+41360050413601214136380241363888413473624134748041368479413693130.177000.000000.000001includedHepG2U2AF1
MXERBX1ENSG00000100387.8chr22+41360050413601214136380241363888413495584134963741368479413693130.168000.000010.000271includedHepG2U2AF1
MXERBX1ENSG00000100387.8chr22+41360050413601214136380241363888413495584134963741368479413693130.127000.000900.037821includedK562LIN28B
MXERBX1ENSG00000100387.8chr22+41349527413496374136385041363888413473624134748041368479413693130.058000.000000.000001includedK562AQR
MXERBX1ENSG00000100387.8chr22+41349527413496374136001841360121413473624134748041368479413693130.690000.000010.000121includedK562AQR
MXERBX1ENSG00000100387.8chr22+41349527413496374135999541360121413473624134748041368479413693130.560000.000010.000211includedK562AQR
MXERBX1ENSG00000100387.8chr22+41349527413496374136005041360154413473624134748041363802413638880.383000.016200.093101includedK562AQR
MXERBX1ENSG00000100387.8chr22+41349467413496374136001841360121413473624134748041368479413693130.548000.000910.008411includedK562AQR
MXERBX1ENSG00000100387.8chr22+41349467413496374135999541360121413473624134748041368479413693130.400000.001990.016571includedK562AQR
MXERBX1ENSG00000100387.8chr22+4136001841360121413638024136385041347362413474804136847941369313-0.328000.011720.071992includedK562AQR
MXERBX1ENSG00000100387.8chr22+4134955841349637413638024136388841347362413474804136847941369313-0.090000.010210.094062includedK562U2AF2
MXERBX1ENSG00000100387.8chr22+4134955841349637413600504136012141347362413474804136380241363888-0.094000.003320.091972includedHepG2BCCIP
MXERBX1ENSG00000100387.8chr22+41360050413601214136380241363888413473624134748041368479413693130.064000.000200.009371includedHepG2PCBP1
MXERBX1ENSG00000100387.8chr22+4134955841349637413638024136388841347362413474804136847941369313-0.107000.000480.046002includedK562PUM1
MXERBX1ENSG00000100387.8chr22+41360050413602384136380241363888413495584134963741368479413693130.178000.000110.007001includedHepG2TIAL1
MXERBX1ENSG00000100387.8chr22+41360050413602384136380241363888413473624134748041368479413693130.065000.000090.006081includedHepG2TIAL1
MXERBX1ENSG00000100387.8chr22+41360050413601214136380241363888413473624134748041368479413693130.072000.000690.025661includedHepG2TIAL1
MXERBX1ENSG00000100387.8chr22+41360050413601214136380241363888413495584134963741368479413693130.178000.000060.004581includedHepG2TIAL1
MXERBX1ENSG00000100387.8chr22+4134955841349637413638024136388841347362413474804136847941369313-0.116000.000630.060412includedHepG2PRPF8
MXERBX1ENSG00000100387.8chr22+41360050413601544136380241363888413473624134748041368479413693130.055000.002940.054951includedK562SUPV3L1
MXERBX1ENSG00000100387.8chr22+41360050413601214136380241363888413473624134748041368479413693130.075000.001500.033341includedK562SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RBX1 is not avaliable on ENCORE database.