PTPN21

General Information

Gene Name       : PTPN21
Gene ID             : ENSG00000070778.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PTPN21)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PTPN21ENSG00000070778.120.020.020.02ENCSR000AEF
HepG2PTPN21ENSG00000070778.122.432.622.53ENCSR985KAT
K562PTPN21ENSG00000070778.120.760.830.79ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PTPN21 is not avaliable on ENCORE database.



Proteins bound to RNA

  • NO known proteins bind on PTPN21 RNA with finished eCLIP experiments on ENCORE database.





eCLIP assay for PTPN21 is not avaliable on ENCORE database.






NO known proteins are bound to PTPN21 RNA with finished eCLIP experiments on ENCORE database.





eCLIP assay for PTPN21 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PTPN21 is not available on ENCORE database.

  • 106 RBPs can affect the levels of PTPN21.  








The Knockdown/knockout RNA-Seq assay for PTPN21 is not available on ENCORE database.





106 RBPs can affect the gene expression of PTPN21 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PTPN21ENSG00000070778.8681.08750227.545101.5816037.9750036.35460HepG2ACO1
PTPN21ENSG00000070778.8554.18620132.248702.0670025.6536024.22310HepG2AKAP1
PTPN21ENSG00000070778.8449.91720228.611300.9767012.0032010.55540HepG2AKAP8L
PTPN21ENSG00000070778.8210.16490109.414500.941604.672003.66490HepG2ASCC1
PTPN21ENSG00000070778.8426.64440281.079900.602003.768202.14050HepG2ATP5C1
PTPN21ENSG00000070778.8605.77880282.278101.1016017.5814016.12630HepG2AUH
PTPN21ENSG00000070778.8388.02370236.528500.714005.363404.33400HepG2CALR
PTPN21ENSG00000070778.8376.32320103.954601.855909.964008.57550HepG2CIRBP
PTPN21ENSG00000070778.8324.67350227.492200.513103.484902.75370HepG2CKAP4
PTPN21ENSG00000070778.8484.98280304.050800.673503.321402.47660HepG2CNOT7
PTPN21ENSG00000070778.8248.23500337.09980-0.441502.000401.40510HepG2CPSF6
PTPN21ENSG00000070778.8128.13050191.46340-0.579502.573801.59520HepG2YBX3
PTPN21ENSG00000070778.8305.24650162.968700.905305.099703.06630HepG2CSTF2T
PTPN21ENSG00000070778.8584.27010270.458501.1111012.9300011.73940HepG2CELF1
PTPN21ENSG00000070778.8273.02060191.742700.509702.636501.50790HepG2DDX1
PTPN21ENSG00000070778.8343.50500175.550900.968307.591006.52410HepG2DDX21
PTPN21ENSG00000070778.8229.39190126.662400.856704.099303.35040HepG2DDX3X
PTPN21ENSG00000070778.8246.46020153.608500.682003.686302.12900HepG2DDX52
PTPN21ENSG00000070778.8372.25930174.901901.089707.589506.38500HepG2DDX55
PTPN21ENSG00000070778.8788.20000382.801001.041907.084405.55850HepG2DDX59
PTPN21ENSG00000070778.8203.44980108.857100.902102.779802.16060HepG2DDX6
PTPN21ENSG00000070778.8309.33290188.019900.718205.242904.30380HepG2DNAJC21
PTPN21ENSG00000070778.8253.00440161.684900.645902.601301.53240HepG2AGO1
PTPN21ENSG00000070778.8268.44010104.595901.359709.664108.59710HepG2EIF2S1
PTPN21ENSG00000070778.8364.29450236.294600.624403.968802.57280HepG2EIF2S2
PTPN21ENSG00000070778.8286.52500148.795500.945205.400404.16980HepG2EIF3D
PTPN21ENSG00000070778.8430.40990115.566001.8969021.8803020.12510HepG2EIF4A3
PTPN21ENSG00000070778.8677.55080112.566902.5894037.0763034.79320HepG2EIF4B
PTPN21ENSG00000070778.8386.66180286.898100.430402.848002.00160HepG2EIF4G1
PTPN21ENSG00000070778.8155.31270274.82610-0.823304.791403.73640HepG2EIF4G2
PTPN21ENSG00000070778.81124.29750324.096901.7944059.8529057.73920HepG2ETF1
PTPN21ENSG00000070778.8452.54900222.349201.0251010.957309.32460HepG2EWSR1
PTPN21ENSG00000070778.8878.82960314.553501.4822019.2449017.54280HepG2FIP1L1
PTPN21ENSG00000070778.8144.5796088.959600.700502.566501.80810HepG2FUBP3
PTPN21ENSG00000070778.8332.06070116.676101.5088013.4581012.05430HepG2FXR1
PTPN21ENSG00000070778.8541.79880108.194802.3240024.9458023.02680HepG2G3BP1
PTPN21ENSG00000070778.8275.34780114.914101.260608.953107.33820HepG2G3BP2
PTPN21ENSG00000070778.8284.49960132.485401.102508.113906.62340HepG2GEMIN5
PTPN21ENSG00000070778.8404.68500173.762801.2196011.559309.46050HepG2GNB2L1
PTPN21ENSG00000070778.8267.14930382.13430-0.516402.444401.83900HepG2GPKOW
PTPN21ENSG00000070778.8493.06680189.820901.3770016.4307015.06800HepG2HNRNPA1
PTPN21ENSG00000070778.8366.53680211.132400.795705.317904.37990HepG2HNRNPC
PTPN21ENSG00000070778.8265.79160382.09080-0.523603.523102.72190HepG2HNRNPF
PTPN21ENSG00000070778.8172.52190109.648900.653802.160901.53850HepG2HNRNPK
PTPN21ENSG00000070778.8863.15900364.677301.2429017.8217016.42610HepG2HNRNPLL
PTPN21ENSG00000070778.8329.14190217.013900.600803.611302.53590HepG2HNRNPM
PTPN21ENSG00000070778.8241.50210376.25460-0.639704.336903.44730HepG2IGF2BP1
PTPN21ENSG00000070778.8547.85600109.963702.3167036.4754034.34730HepG2IGF2BP2
PTPN21ENSG00000070778.8465.78040103.252502.1734012.7942010.84720HepG2IGF2BP3
PTPN21ENSG00000070778.8357.44270214.241000.738407.209706.08650HepG2ILF2
PTPN21ENSG00000070778.8267.84160110.630801.275507.754305.98980HepG2KHSRP
PTPN21ENSG00000070778.8791.97880426.280700.893607.630106.23650HepG2LARP4
PTPN21ENSG00000070778.8293.56960116.717101.330609.973308.75070HepG2MAGOH
PTPN21ENSG00000070778.8234.20070144.159700.700003.651801.80660HepG2MARK2
PTPN21ENSG00000070778.8322.63050117.358201.4589011.2457010.03610HepG2MATR3
PTPN21ENSG00000070778.8258.91340155.733200.733302.473201.47620HepG2METAP2
PTPN21ENSG00000070778.8590.60910254.556001.2141015.6934013.94470HepG2MSI2
PTPN21ENSG00000070778.8206.26100120.112800.780003.311502.62110HepG2NCBP2
PTPN21ENSG00000070778.8179.88980323.35230-0.846005.126504.12070HepG2NSUN2
PTPN21ENSG00000070778.8268.27330106.922801.327009.797808.45840HepG2PABPC4
PTPN21ENSG00000070778.8313.60280102.786701.6092019.2167017.85160HepG2PCBP1
PTPN21ENSG00000070778.8349.97150134.949401.3747011.7308010.23410HepG2PRPF8
PTPN21ENSG00000070778.8475.35900104.584602.1842040.6742039.09270HepG2PTBP1
PTPN21ENSG00000070778.8511.11610292.203400.8066011.1600010.13650HepG2PUM1
PTPN21ENSG00000070778.8673.13890291.984901.2049019.3961017.71720HepG2PUM2
PTPN21ENSG00000070778.8403.68720231.769000.800504.931104.15170HepG2PUS1
PTPN21ENSG00000070778.8273.64940113.277801.2724010.216209.12290HepG2QKI
PTPN21ENSG00000070778.8745.59400204.201201.8683016.0775014.51930HepG2RAVER1
PTPN21ENSG00000070778.8924.24860270.884301.7705047.0510045.42090HepG2RBM22
PTPN21ENSG00000070778.8352.63770102.803101.7782021.0007019.25010HepG2RBM25
PTPN21ENSG00000070778.8263.17620166.676600.658902.642501.60900HepG2RCC2
PTPN21ENSG00000070778.8531.14740116.396502.1900041.1727039.63990HepG2NELFE
PTPN21ENSG00000070778.8259.59190108.400501.2598010.268009.19610HepG2RECQL
PTPN21ENSG00000070778.8290.95570144.777901.006907.388006.44180HepG2RPS19
PTPN21ENSG00000070778.8441.84820189.305101.2227012.0320010.46080HepG2RPS2
PTPN21ENSG00000070778.8344.55790193.234300.834305.650704.10020HepG2RPS5
PTPN21ENSG00000070778.8379.94900133.495501.5089013.4432011.93190HepG2RRP9
PTPN21ENSG00000070778.898.83670186.78510-0.918305.408104.55950HepG2SAFB2
PTPN21ENSG00000070778.8231.18650145.317800.669703.106802.10780HepG2SERBP1
PTPN21ENSG00000070778.8593.10680272.712401.120809.735008.40900HepG2SF3A3
PTPN21ENSG00000070778.8368.19410108.894501.7574022.7417021.32300HepG2SF3B4
PTPN21ENSG00000070778.8418.12230217.831200.9406011.2710010.11050HepG2SMN1
PTPN21ENSG00000070778.8920.70750305.952401.5893045.5022044.11660HepG2SRFBP1
PTPN21ENSG00000070778.8507.65430113.658902.1590039.8240038.48820HepG2SRSF1
PTPN21ENSG00000070778.8650.94810388.387100.744902.382301.46160HepG2SRSF3
PTPN21ENSG00000070778.8518.61950271.783900.9321012.5703011.36840HepG2SRSF5
PTPN21ENSG00000070778.8346.6331092.464601.9063028.7582027.34230HepG2SRSF9
PTPN21ENSG00000070778.8442.00270265.636600.734507.616506.84710HepG2SSB
PTPN21ENSG00000070778.8592.99030309.084800.9399013.6414012.43210HepG2SUCLG1
PTPN21ENSG00000070778.8590.77370174.119901.7624021.1071019.55180HepG2SUPV3L1
PTPN21ENSG00000070778.8207.30310102.151501.020903.463502.84790HepG2TAF15
PTPN21ENSG00000070778.8468.38780355.433200.398002.079801.43880HepG2TARDBP
PTPN21ENSG00000070778.8243.13950116.711201.058706.161204.77140HepG2TFIP11
PTPN21ENSG00000070778.8208.8743093.873401.153707.768706.38180HepG2TIA1
PTPN21ENSG00000070778.8296.57880203.830000.540903.085702.56240HepG2TIAL1
PTPN21ENSG00000070778.8686.85800269.067001.3519017.5308015.89520HepG2U2AF1
PTPN21ENSG00000070778.8882.83370313.080501.495505.822704.34210HepG2U2AF2
PTPN21ENSG00000070778.8521.35500284.662400.872906.261904.97230HepG2UBE2L3
PTPN21ENSG00000070778.8390.14950233.501200.740506.545905.69070HepG2UTP3
PTPN21ENSG00000070778.8353.45160200.653000.816704.037802.50690HepG2XRCC5
PTPN21ENSG00000070778.8374.15610224.484200.736903.575202.37150HepG2XRCC6
PTPN21ENSG00000070778.8420.95430181.430701.2141016.8862015.46690HepG2ZC3H8
PTPN21ENSG00000070778.8462.90150265.993600.799209.297608.44620HepG2ZNF622
PTPN21ENSG00000070778.8170.0209090.364300.911804.726303.90650K562DDX47
PTPN21ENSG00000070778.895.2770037.488001.345605.002604.22360K562FXR1
PTPN21ENSG00000070778.8108.2557049.153901.139003.963403.26440K562HNRNPC
PTPN21ENSG00000070778.898.8281054.740400.852202.121501.31600K562KRR1
PTPN21ENSG00000070778.881.9463042.971500.931202.112501.45320K562PRPF8
PTPN21ENSG00000070778.8284.80930114.404001.3158010.375408.77950K562PUF60
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PTPN21 is not available on ENCORE database.





1 RBPs can affect the splicing of PTPN21 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
MXEPTPN21ENSG00000070778.8chr14-8896354688963634889671268896721588962756889628368896762488967712-0.436000.000050.000632includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PTPN21 is not avaliable on ENCORE database.