PPP3R1

General Information

Gene Name       : PPP3R1
Gene ID             : ENSG00000221823.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PPP3R1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPP3R1ENSG00000221823.1035.1529.2932.22ENCSR000AEF
HepG2PPP3R1ENSG00000221823.1021.6040.0930.85ENCSR985KAT
K562PPP3R1ENSG00000221823.1031.9132.8132.36ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPP3R1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPP3R1 RNA is bound by 37 proteins.  







eCLIP assay for PPP3R1 is not avaliable on ENCORE database.





37 proteins are bound to PPP3R1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr26840753368407628-3'-UTR,intron-Distal4.661489.59063HepG2UPF1
chr26840619768406243-3'-UTR,intron-Distal3.732564.59124HepG2FUBP3
chr26840619268406270-3'-UTR,intron-Distal4.6199855.60429K562PUM2
chr26840741468407450-3'-UTR,intron-Distal3.640717.65557K562FAM120A
chr26840762868407736-3'-UTR,intron-Distal6.3793721.73270HepG2UPF1
chr26840788368407924-3'-UTR,intron-Distal,intron-Proximal3.569015.37252K562YBX3
chr26840602368406106-3'-UTR,intron-Distal3.4873413.80452HepG2FUBP3
chr26840602568406074-3'-UTR,intron-Distal5.0647444.92919K562UPF1
chr26840658168406649-3'-UTR,intron-Distal4.015057.60084HepG2UPF1
chr26840606968406100-3'-UTR,intron-Distal3.469474.77974K562TIA1
chr26840664968406734-3'-UTR,intron-Distal4.2644217.43328K562FAM120A
chr26840602068406095-3'-UTR,intron-Distal3.2976510.88111K562ZC3H11A
chr26840752568407617-3'-UTR,intron-Distal3.461326.39870HepG2AKAP1
chr26840673868406801-3'-UTR,intron-Distal4.541926.44805K562IGF2BP1
chr26840601568406077-3'-UTR,intron-Distal4.144269.99818K562APOBEC3C
chr26840603468406080-3'-UTR,intron-Distal4.742623.55542HepG2TIAL1
chr26840712368407140-3'-UTR,intron-Distal3.523416.25570K562UPF1
chr26840675268406790-3'-UTR,intron-Distal4.208863.54514K562TIA1
chr26840674468406817-3'-UTR,intron-Distal3.7335720.24982K562FAM120A
chr26840602568406075-3'-UTR,intron-Distal5.108887.33810HepG2TIA1
chr26840619568406248-3'-UTR,intron-Distal3.334624.99882K562TIA1
chr26840801868408087-3'-UTR,intron-Distal,intron-Proximal3.106515.02670K562TIA1
chr26840668968406736-3'-UTR,intron-Distal4.5679219.04148K562UPF1
chr26840719268407276-3'-UTR,intron-Distal3.6814213.90556K562FAM120A
chr26840698668407059-3'-UTR,intron-Distal3.180348.99323K562FAM120A
chr26840654468406648-3'-UTR,intron-Distal3.002648.02338K562FAM120A
chr26840619368406252-3'-UTR,intron-Distal4.295943.84732HepG2TIA1
chr26840602668406074-3'-UTR,intron-Distal4.2994851.49617K562DDX6
chr26840757668407624-3'-UTR,intron-Distal3.5748214.79871K562UPF1
chr26840601468406098-3'-UTR,intron-Distal3.797435.74545K562CPEB4
chr26840674368406867-3'-UTR,intron-Distal4.8959115.10113HepG2UPF1
chr26840697368407001-3'-UTR,intron-Distal4.033664.32914K562YBX3
chr26840752468407582-3'-UTR,intron-Distal3.4609812.16237K562FAM120A
chr26840669868406804-3'-UTR,intron-Distal3.7939612.32481HepG2AKAP1
chr26840681268406870-3'-UTR,intron-Distal3.748485.14978HepG2AKAP1
chr26840673668406816-3'-UTR,intron-Distal4.2321439.74834K562UPF1
chr26840751668407576-3'-UTR,intron-Distal3.8733017.96067K562UPF1
chr26840738568407437-3'-UTR,intron-Distal4.280583.87385HepG2AKAP1
chr26840607768406124-3'-UTR,intron-Distal3.140153.10134K562APOBEC3C
chr26840601368406069-3'-UTR,intron-Distal5.3440131.04328K562TIA1
chr26840657668406646-3'-UTR,intron-Distal3.2811712.86265K562UPF1
chr26840607568406123-3'-UTR,intron-Distal4.195684.87318HepG2TIA1
chr26840607468406118-3'-UTR,intron-Distal4.3466523.01091K562DDX6
chr26840762468407732-3'-UTR,intron-Distal3.7500427.19131K562UPF1
chr26840763668407721-3'-UTR,intron-Distal5.262469.44144HepG2AKAP1
chr26840602768406102-3'-UTR,intron-Distal3.025115.06814HepG2UPF1
chr26840607468406113-3'-UTR,intron-Distal6.8489825.72087K562UPF1
chr26840681768406871-3'-UTR,intron-Distal4.5822019.99987K562UPF1
chr26847930568479400-5'-UTR,intron-Distal4.865107.08021K562HNRNPK
chr26847933968479394-5'-UTR,intron-Distal3.023356.47667HepG2DDX59
chr26847962468479665-5'-UTR,intron-Distal,intron-Proximal3.545007.73893K562DDX3X
chr26847956168479667-5'-UTR,intron-Distal,intron-Proximal3.3840315.48893HepG2DDX3X
chr26847942768479494-5'-UTR,intron-Distal3.434614.57279K562PTBP1
chr26847934268479403-5'-UTR,intron-Distal5.051528.98402K562PCBP1
chr26847949068479599-5'-UTR,intron-Distal3.7210512.73189K562PCBP1
chr26847933868479401-5'-UTR,intron-Distal3.480373.64078HepG2PCBP1
chr26847947768479580-5'-UTR,intron-Distal5.1441624.54196HepG2PCBP2
chr26847962568479670-5'-UTR,intron-Distal,intron-Proximal3.962305.97588K562PCBP1
chr26847940168479472-5'-UTR,intron-Distal5.039576.56740HepG2PCBP1
chr26847940668479477-5'-UTR,intron-Distal5.7439118.97112HepG2PCBP2
chr26847956068479624-5'-UTR,intron-Distal3.6612914.16750K562DDX3X
chr26847958568479628-5'-UTR,intron-Distal4.248754.49279K562DROSHA
chr26847957468479666-5'-UTR,intron-Distal,intron-Proximal3.957556.09067HepG2NCBP2
chr26847940368479471-5'-UTR,intron-Distal3.188089.00262K562PCBP1
chr26847935168479393-5'-UTR,intron-Distal4.512837.31085HepG2PCBP2
chr26841557468415678-CDS,intron-Distal,intron-Proximal3.211684.07440K562PRPF8
chr26844084768440906-intron-Distal4.025553.71397K562KHSRP
chr26841682368416839-intron-Distal3.831493.66668K562KHSRP
chr26845210568452154-intron-Distal3.219586.23972K562KHSRP
chr26844289668442968-intron-Distal3.594574.41421K562PTBP1
chr26844256268442633-intron-Distal7.1980135.16814K562EXOSC5
chr26843240168432460-intron-Distal4.438374.23668K562LIN28B
chr26841655668416614-intron-Distal3.942958.11138K562KHSRP
chr26844408168444169-intron-Distal,intron-Proximal3.917293.48768HepG2KHSRP
chr26844228368442318-intron-Distal5.164778.36716K562EXOSC5
chr26844242768442473-intron-Distal6.1629617.32582K562EXOSC5
chr26847906068479134-intron-Distal3.560105.19749HepG2XRN2
chr26844116868441203-intron-Distal3.916028.47709K562EXOSC5
chr26844219268442228-intron-Distal5.053577.06230K562EXOSC5
chr26844066268440687-intron-Distal3.719035.20960K562EXOSC5
chr26846671668466751-intron-Distal4.059523.84389HepG2SUGP2
chr26846647568466521-intron-Distal3.321564.08528HepG2SUGP2
chr26846550068465579-intron-Distal4.763214.66737HepG2MATR3
chr26844150368441582-intron-Distal5.3797020.39543K562EXOSC5
chr26842830968428389-intron-Distal4.435705.60468K562SAFB2
chr26844103168441074-intron-Distal3.660737.41097K562EXOSC5
chr26844208668442151-intron-Distal4.493878.56038K562HNRNPM
chr26842739568427471-intron-Distal3.580223.01412K562SAFB2
chr26844201068442037-intron-Distal3.677544.61282K562EXOSC5
chr26844059668440637-intron-Distal4.323158.21369K562EXOSC5
chr26844112968441162-intron-Distal3.249734.46810K562EXOSC5
chr26844250968442624-intron-Distal3.841969.25247K562HNRNPM
chr26847915468479219-intron-Distal3.360407.88033HepG2NKRF
chr26846201968462108-intron-Distal5.091664.99795K562QKI
chr26847916768479201-intron-Distal3.303265.47764HepG2XRN2
chr26844078168440846-intron-Distal4.7367312.54948K562EXOSC5
chr26842604368426094-intron-Distal3.841953.37923K562KHDRBS1
chr26844140868441459-intron-Distal4.233663.60235HepG2HNRNPM
chr26844120368441275-intron-Distal5.4460320.06847K562EXOSC5
chr26845818868458269-intron-Distal3.288543.95154K562SAFB2
chr26841246168412536-intron-Distal3.802953.08967K562KHDRBS1
chr26847717268477226-intron-Distal4.239324.10336HepG2SUGP2
chr26844409568444161-intron-Distal,intron-Proximal4.070897.54016K562TARDBP
chr26846588068465936-intron-Distal3.500484.36087HepG2MATR3
chr26844208368442155-intron-Distal4.065144.61500HepG2HNRNPM
chr26841661468416677-intron-Distal4.989519.15655K562KHSRP
chr26847896768479028-intron-Distal5.095747.75987HepG2XRN2
chr26845195068452034-intron-Distal4.228839.41035K562KHSRP
chr26847834468478432-intron-Distal,intron-Proximal3.859094.77518HepG2U2AF2
chr26846173468461808-intron-Distal4.263996.86842HepG2U2AF2
chr26842863268428734-intron-Distal3.045023.46712K562SAFB2
chr26844063968440695-intron-Distal3.996863.90026K562KHSRP
chr26847907768479154-intron-Distal4.8580110.22203HepG2NKRF
chr26847895268479051-intron-Distal4.890576.21911K562XRN2
chr26841343868413538-intron-Distal,intron-Proximal3.518957.48221K562KHSRP
chr26844300568443054-intron-Distal4.810666.91139HepG2QKI
chr26844426368444275-intron-Distal,intron-Proximal3.488193.93753K562U2AF2
chr26841343968413515-intron-Distal,intron-Proximal3.950973.22073HepG2KHSRP
chr26847720868477284-intron-Distal4.300213.62238HepG2MATR3
chr26846201468462091-intron-Distal3.8223211.78347HepG2QKI
chr26844059068440622-intron-Distal3.598753.10641K562HNRNPM
chr26844233668442411-intron-Distal5.2684128.09908K562EXOSC5
chr26845203468452105-intron-Distal4.0916412.30466K562KHSRP
chr26843331868433385-intron-Distal4.343323.42734K562PTBP1
chr26840589968405984-intron-Distal,intron-Proximal3.062885.91447HepG2CSTF2
chr26841641368416494-intron-Distal3.168697.36118K562KHSRP
chr26844127568441319-intron-Distal4.5277610.61559K562EXOSC5
chr26840590868405966-intron-Distal,intron-Proximal4.310005.01722K562CSTF2T
chr26844062268440638-intron-Distal3.550103.10641K562HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPP3R1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPP3R1 is not available on ENCORE database.

  • 84 RBPs can affect the levels of PPP3R1.  








The Knockdown/knockout RNA-Seq assay for PPP3R1 is not available on ENCORE database.





84 RBPs can affect the gene expression of PPP3R1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPP3R1ENSG00000221823.61434.654701061.712700.434203.766202.52680HepG2AATF
PPP3R1ENSG00000221823.61120.230101661.34200-0.568605.056903.82340HepG2ABCF1
PPP3R1ENSG00000221823.61913.878701419.752900.430808.265307.32870HepG2ACO1
PPP3R1ENSG00000221823.62910.963902038.769600.513704.384703.73620HepG2AKAP1
PPP3R1ENSG00000221823.62081.198401686.899200.302902.046201.36670HepG2ASCC1
PPP3R1ENSG00000221823.62218.539001713.108400.372903.516802.85140HepG2BOP1
PPP3R1ENSG00000221823.61240.616201419.37160-0.194201.991901.41570HepG2CKAP4
PPP3R1ENSG00000221823.62507.420302143.125500.226402.266301.67480HepG2CELF1
PPP3R1ENSG00000221823.62032.581802304.68990-0.181302.582001.86170HepG2DAZAP1
PPP3R1ENSG00000221823.61388.007301146.405100.275802.085601.30330HepG2DDX24
PPP3R1ENSG00000221823.62601.604401952.962400.413603.411802.72580HepG2DDX3X
PPP3R1ENSG00000221823.62470.997301677.693200.558504.990004.18250HepG2DDX6
PPP3R1ENSG00000221823.61150.679301358.30000-0.239302.251801.63060HepG2DKC1
PPP3R1ENSG00000221823.6744.925301262.76670-0.7614019.5335017.95230HepG2DNAJC2
PPP3R1ENSG00000221823.61256.394501782.24990-0.504403.965603.20470HepG2EIF4A3
PPP3R1ENSG00000221823.62285.686101735.323600.397302.281701.65380HepG2EIF4B
PPP3R1ENSG00000221823.61121.94960814.394800.462104.101703.15340HepG2FUBP3
PPP3R1ENSG00000221823.61368.681301782.83200-0.381402.666302.03580HepG2GPKOW
PPP3R1ENSG00000221823.61618.662801355.413500.256002.959601.95300HepG2HDGF
PPP3R1ENSG00000221823.6950.839601286.26620-0.435904.171703.40040HepG2HNRNPA1
PPP3R1ENSG00000221823.62466.096102117.929500.219502.271501.41690HepG2HNRNPA2B1
PPP3R1ENSG00000221823.61087.943901430.71880-0.395103.441902.67430HepG2HNRNPC
PPP3R1ENSG00000221823.61227.074401622.51800-0.403005.606304.62850HepG2HNRNPF
PPP3R1ENSG00000221823.61413.083302099.48830-0.5712016.3993014.87880HepG2HNRNPL
PPP3R1ENSG00000221823.61192.921601421.26080-0.252702.676402.08010HepG2HNRNPU
PPP3R1ENSG00000221823.61186.925301597.71910-0.428804.897503.96050HepG2IGF2BP1
PPP3R1ENSG00000221823.6626.014401695.61450-1.4375028.8985026.99710HepG2IGF2BP2
PPP3R1ENSG00000221823.61013.526301451.77340-0.5184011.020909.66220HepG2ILF2
PPP3R1ENSG00000221823.61442.795901808.98270-0.326301.978001.44000HepG2MATR3
PPP3R1ENSG00000221823.61621.722402285.30950-0.494907.077805.86850HepG2NOL12
PPP3R1ENSG00000221823.62659.415701646.628200.691504.420803.28310HepG2PABPC1
PPP3R1ENSG00000221823.6630.363501135.33690-0.848907.108005.88420HepG2PRPF8
PPP3R1ENSG00000221823.61377.313101618.23460-0.232602.134601.64200HepG2PTBP1
PPP3R1ENSG00000221823.61691.791102181.44360-0.366703.923803.22770HepG2PUF60
PPP3R1ENSG00000221823.61935.274802313.96990-0.257802.666302.00830HepG2PUM2
PPP3R1ENSG00000221823.61209.949501446.09980-0.257202.952602.32150HepG2PUS1
PPP3R1ENSG00000221823.62527.774601752.527000.528309.198708.15810HepG2QKI
PPP3R1ENSG00000221823.62865.762301364.992801.069908.290107.11150HepG2RAVER1
PPP3R1ENSG00000221823.62373.362201590.554000.577308.782307.63060HepG2RBM25
PPP3R1ENSG00000221823.61878.870801538.951500.287802.325501.42410HepG2RBM27
PPP3R1ENSG00000221823.61839.895201448.813800.344702.558101.52660HepG2RPS5
PPP3R1ENSG00000221823.6523.857601123.12650-1.100309.693808.35080HepG2RRP9
PPP3R1ENSG00000221823.6850.731701265.70420-0.5732010.914009.76730HepG2SAFB2
PPP3R1ENSG00000221823.62322.983901764.012800.397002.582201.93010HepG2SF3A3
PPP3R1ENSG00000221823.61611.468402091.46150-0.376107.128906.08600HepG2SLBP
PPP3R1ENSG00000221823.62534.974001873.794700.435902.383001.65990HepG2SNRNP70
PPP3R1ENSG00000221823.63506.559402579.927100.4426011.1156010.29280HepG2SRFBP1
PPP3R1ENSG00000221823.62474.501601758.524500.4927010.8359010.03410HepG2SRSF1
PPP3R1ENSG00000221823.62394.171801812.013600.401802.558401.59950HepG2SRSF3
PPP3R1ENSG00000221823.61302.716701594.06320-0.291203.445302.68020HepG2SRSF7
PPP3R1ENSG00000221823.61914.279601430.671400.420002.872902.31310HepG2SRSF9
PPP3R1ENSG00000221823.61531.473402240.00220-0.5486012.7760011.83320HepG2SSB
PPP3R1ENSG00000221823.62058.330401275.584000.690205.338103.66950HepG2SUB1
PPP3R1ENSG00000221823.62010.575901452.375800.469106.268305.01490HepG2TIA1
PPP3R1ENSG00000221823.6809.536701381.07490-0.7706013.9204012.94800HepG2TIAL1
PPP3R1ENSG00000221823.61041.843601393.36230-0.419406.177905.39570HepG2TRIM56
PPP3R1ENSG00000221823.62736.618401435.354200.9309017.3320015.70640HepG2U2AF1
PPP3R1ENSG00000221823.61269.968401607.98250-0.340504.264102.99580HepG2UTP18
PPP3R1ENSG00000221823.61925.444501510.375000.350205.175704.40000HepG2UTP3
PPP3R1ENSG00000221823.62116.116301342.047500.656905.146403.40610HepG2XRCC5
PPP3R1ENSG00000221823.62025.797201501.008100.432502.492601.48940HepG2XRCC6
PPP3R1ENSG00000221823.6965.719001441.79750-0.578203.577302.76070HepG2XRN2
PPP3R1ENSG00000221823.62272.652503006.77320-0.403804.043502.54000K562ABCF1
PPP3R1ENSG00000221823.62527.804801815.947700.4771010.187109.18790K562AGGF1
PPP3R1ENSG00000221823.62432.306701889.581000.364203.634602.88250K562AKAP8L
PPP3R1ENSG00000221823.63841.859402620.467200.551907.225806.34930K562AQR
PPP3R1ENSG00000221823.64402.172003623.314000.280803.789102.64000K562CELF1
PPP3R1ENSG00000221823.63959.033702485.981200.6712010.098208.94380K562DDX47
PPP3R1ENSG00000221823.62389.772502033.292200.233002.532401.69880K562DKC1
PPP3R1ENSG00000221823.6975.36930614.090400.667403.821902.61700K562EIF3A
PPP3R1ENSG00000221823.61749.703402161.36380-0.304802.460301.66190K562FIP1L1
PPP3R1ENSG00000221823.62299.770301491.249900.6249011.2208010.08850K562FXR1
PPP3R1ENSG00000221823.62250.773301507.311800.578302.178201.56120K562G3BP2
PPP3R1ENSG00000221823.61978.722201569.828500.333903.254102.08860K562HNRNPA1
PPP3R1ENSG00000221823.62348.832702930.35640-0.319102.760801.96650K562HSPD1
PPP3R1ENSG00000221823.6898.384501803.86440-1.0057013.4405010.70420K562IGF2BP2
PPP3R1ENSG00000221823.62773.195202005.299700.467602.895702.04930K562KIF1C
PPP3R1ENSG00000221823.62383.039801919.579800.311902.789601.70890K562MAK16
PPP3R1ENSG00000221823.62960.455802246.444600.398104.644403.40330K562MBNL1
PPP3R1ENSG00000221823.62357.406001574.596600.582103.474302.46130K562NAA15
PPP3R1ENSG00000221823.61903.938602453.56930-0.365903.319802.40680K562PPIG
PPP3R1ENSG00000221823.61272.672401842.61190-0.533905.671304.75010K562PTBP1
PPP3R1ENSG00000221823.64853.489303215.866800.593709.591208.04870K562PUF60
PPP3R1ENSG00000221823.65659.348803419.955800.726608.219006.30100K562PUM1
PPP3R1ENSG00000221823.63030.367601873.909200.6933010.006509.02100K562PUS1
PPP3R1ENSG00000221823.62709.423801825.872600.5693011.2639010.08810K562RBM15
PPP3R1ENSG00000221823.6651.61860953.62910-0.549403.185802.11580K562RCC2
PPP3R1ENSG00000221823.61868.491401413.908300.402102.675801.87520K562RPS19
PPP3R1ENSG00000221823.61337.863001058.375600.338002.784001.69780K562SAFB
PPP3R1ENSG00000221823.62310.091301815.397200.347604.831803.77970K562SF3A3
PPP3R1ENSG00000221823.61900.485101191.352500.6737011.9317010.22520K562SYNCRIP
PPP3R1ENSG00000221823.62017.562501508.880600.419005.248004.14790K562U2AF2
PPP3R1ENSG00000221823.62380.781101735.795600.4557010.265908.75310K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPP3R1 is not available on ENCORE database.





1 RBPs can affect the splicing of PPP3R1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSPPP3R1ENSG00000221823.6chr2-6840807868408275684080786840814268413599684137220.051000.000000.00000longerK562AQR
MXEPPP3R1ENSG00000221823.6chr2-68413599684137226841372268413784684079356840814268415645684158220.128000.000000.000001includedK562AQR
MXEPPP3R1ENSG00000221823.6chr2-6841564568415822684442236844426368413599684137846847925668479663-0.548000.000000.000012includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPP3R1 is not avaliable on ENCORE database.