PNPO

General Information

Gene Name       : PNPO
Gene ID             : ENSG00000108439.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PNPO)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PNPOENSG00000108439.1026.0827.3226.70ENCSR000AEF
HepG2PNPOENSG00000108439.1024.2433.2528.74ENCSR985KAT
K562PNPOENSG00000108439.1021.3523.8622.61ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PNPO is not avaliable on ENCORE database.



Proteins bound to RNA
  • PNPO RNA is bound by 13 proteins.  







eCLIP assay for PNPO is not avaliable on ENCORE database.





13 proteins are bound to PNPO RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr174602537046025424+3'-UTR,intron-Distal5.439926.76118K562LIN28B
chr174602547546025569+3'-UTR,intron-Distal4.6620720.03105K562UPF1
chr174602481146024843+3'-UTR,intron-Distal3.067925.09741K562UPF1
chr174602331046023356+3'-UTR,CDS,intron-Distal,intron-Proximal3.404924.04629HepG2G3BP1
chr174602448346024542+3'-UTR,intron-Distal3.954857.15385HepG2AKAP1
chr174602288946022980+3'-UTR,CDS,intron-Distal,intron-Proximal3.477148.20183HepG2EFTUD2
chr174602438746024471+3'-UTR,intron-Distal5.0158533.74474HepG2UPF1
chr174602469146024746+3'-UTR,intron-Distal3.015793.33646HepG2AKAP1
chr174602295646023025+3'-UTR,CDS,intron-Distal,intron-Proximal3.159256.18341HepG2PRPF8
chr174602326146023344+3'-UTR,CDS,intron-Distal3.073675.97777HepG2PPIG
chr174602449046024526+3'-UTR,intron-Distal4.189084.66555K562FAM120A
chr174602470046024744+3'-UTR,intron-Distal4.067925.48330K562UPF1
chr174602200346022108+3'-UTR,CDS,intron-Proximal3.477525.90680HepG2PPIG
chr174602532546025385+3'-UTR,intron-Distal4.894026.81418HepG2UPF1
chr174602547646025499+3'-UTR,intron-Distal4.128763.19668HepG2UPF1
chr174602456746024620+3'-UTR,intron-Distal4.2976211.34516K562FAM120A
chr174602457546024629+3'-UTR,intron-Distal5.453948.80636K562UPF1
chr174602533146025420+3'-UTR,intron-Distal4.0323315.05942HepG2LIN28B
chr174602422946024291+3'-UTR,intron-Distal3.6839712.30329HepG2PCBP2
chr174602513746025224+3'-UTR,intron-Distal5.381949.50783HepG2UPF1
chr174602428446024350+3'-UTR,intron-Distal4.007016.61024K562FAM120A
chr174602286346023024+3'-UTR,CDS,intron-Distal,intron-Proximal3.567315.40420HepG2AQR
chr174602439146024474+3'-UTR,intron-Distal4.1788115.76818HepG2AKAP1
chr174602468046024738+3'-UTR,intron-Distal4.087535.85347HepG2UPF1
chr174602428546024356+3'-UTR,intron-Distal3.084374.48738K562UPF1
chr174602448146024546+3'-UTR,intron-Distal3.932227.81366HepG2UPF1
chr174602449846024563+3'-UTR,intron-Distal3.852547.13820K562UPF1
chr174602453146024558+3'-UTR,intron-Distal3.909533.38753K562FAM120A
chr174602440546024479+3'-UTR,intron-Distal3.223875.25366HepG2FAM120A
chr174602533946025414+3'-UTR,intron-Distal3.460586.83930K562FAM120A
chr174602458346024633+3'-UTR,intron-Distal4.825276.81418HepG2UPF1
chr174601902846019099+5'-UTR,CDS,intron-Distal,intron-Proximal4.436758.97908HepG2DDX3X
chr174601899446019176+5'-UTR,CDS,intron-Distal,intron-Proximal4.2648810.44075K562DDX3X
chr174601908446019176+5'-UTR,CDS,intron-Distal3.398143.87702HepG2NCBP2
chr174601912546019165+5'-UTR,CDS,intron-Distal4.074574.82666HepG2DDX3X
chr174602073646020800+5'-UTR,CDS,intron-Distal,intron-Proximal3.051125.21025HepG2PPIG
chr174601893646019063+5'-UTR,CDS,intron-Proximal3.429043.40404HepG2NCBP2
chr174602281046022849+intron-Distal,intron-Proximal4.441803.97974HepG2RBFOX2
chr174602252246022577+intron-Distal4.7212111.02685HepG2RBFOX2
chr174602298446023049+intron-Distal,intron-Proximal6.5883314.81270HepG2EFTUD2
chr174602284946022913+intron-Distal,intron-Proximal5.3090013.82570HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PNPO is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PNPO is not available on ENCORE database.

  • 107 RBPs can affect the levels of PNPO.  








The Knockdown/knockout RNA-Seq assay for PNPO is not available on ENCORE database.





107 RBPs can affect the gene expression of PNPO :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PNPOENSG00000108439.52483.496301534.688900.694308.319906.81310HepG2ABCF1
PNPOENSG00000108439.5985.396001161.22300-0.236902.308301.74360HepG2ACO1
PNPOENSG00000108439.5583.754601020.45460-0.805809.631907.91900HepG2ADAR
PNPOENSG00000108439.51412.608302012.30730-0.510504.022803.39850HepG2AKAP1
PNPOENSG00000108439.51458.465301166.580300.322103.877502.98220HepG2AKAP8L
PNPOENSG00000108439.52426.489201665.045700.543205.648304.54790HepG2ASCC1
PNPOENSG00000108439.51373.979101601.83700-0.221402.203201.57790HepG2AUH
PNPOENSG00000108439.51351.42060944.916800.516104.201303.11430HepG2BCLAF1
PNPOENSG00000108439.52432.382501316.022800.8861016.5607015.27440HepG2BOP1
PNPOENSG00000108439.51469.677701149.681100.354202.918401.65440HepG2BUD13
PNPOENSG00000108439.51571.660401153.462100.446205.344004.31620HepG2CALR
PNPOENSG00000108439.51721.267001160.852200.5682013.7040012.45600HepG2CKAP4
PNPOENSG00000108439.51269.284101046.444600.278402.572001.59380HepG2YBX3
PNPOENSG00000108439.5938.735601376.24220-0.551908.884207.85720HepG2CELF1
PNPOENSG00000108439.51410.43770924.832600.608807.253206.20720HepG2DDX21
PNPOENSG00000108439.51201.83460693.627700.7929010.758708.44730HepG2DDX47
PNPOENSG00000108439.51360.778501069.174500.347802.074601.39510HepG2DDX55
PNPOENSG00000108439.51124.633001655.78370-0.558104.628503.84720HepG2DDX6
PNPOENSG00000108439.51277.78370991.083200.366503.030402.00910HepG2DHX30
PNPOENSG00000108439.51722.059601110.945100.6322013.4356012.17250HepG2DKC1
PNPOENSG00000108439.51219.697301018.433700.260102.947002.27710HepG2DNAJC2
PNPOENSG00000108439.51093.53830835.196400.388702.737701.63440HepG2EFTUD2
PNPOENSG00000108439.5936.619001591.89720-0.765209.056808.02170HepG2EIF2S1
PNPOENSG00000108439.52847.846501759.307100.694807.619806.56160HepG2EIF4A3
PNPOENSG00000108439.51159.420101459.91390-0.332502.718901.88800HepG2EIF4G1
PNPOENSG00000108439.51224.452701549.62980-0.339802.101701.42680HepG2FIP1L1
PNPOENSG00000108439.51533.557401247.008000.298302.267101.54930HepG2FUBP3
PNPOENSG00000108439.5765.016901257.55750-0.717105.547104.00390HepG2FUS
PNPOENSG00000108439.51087.648001774.84440-0.706508.257807.11130HepG2FXR1
PNPOENSG00000108439.51035.971801646.54560-0.668506.823905.79850HepG2G3BP1
PNPOENSG00000108439.51793.419301369.608000.388802.788002.14470HepG2GPKOW
PNPOENSG00000108439.51447.429101108.563700.384705.462804.13840HepG2HDGF
PNPOENSG00000108439.51419.343501037.423700.452104.326203.54210HepG2HNRNPA1
PNPOENSG00000108439.5784.77050519.887700.594003.794502.00200HepG2HNRNPD
PNPOENSG00000108439.5704.187401667.00310-1.2432024.7345022.85730HepG2HNRNPK
PNPOENSG00000108439.51035.643901348.00290-0.380305.951104.99460HepG2HNRNPL
PNPOENSG00000108439.52024.533301307.039500.631203.589302.88230HepG2HNRNPLL
PNPOENSG00000108439.51658.245501391.886000.252502.032801.40600HepG2IGF2BP1
PNPOENSG00000108439.5863.462001570.54550-0.863103.427902.33330HepG2IGF2BP3
PNPOENSG00000108439.51020.882301170.90220-0.197802.020401.38250HepG2ILF2
PNPOENSG00000108439.51208.63730895.464900.432603.871601.95010HepG2CCAR2
PNPOENSG00000108439.5678.771701513.08450-1.1565014.8974013.00530HepG2LARP4
PNPOENSG00000108439.52226.953601775.463100.326802.305601.70540HepG2MAGOH
PNPOENSG00000108439.5583.45830839.29460-0.524504.251002.29400HepG2MARK2
PNPOENSG00000108439.51128.241901467.38040-0.379204.270103.32300HepG2NOL12
PNPOENSG00000108439.5773.14100548.561900.495002.150501.38380HepG2PABPC1
PNPOENSG00000108439.5828.209301134.66170-0.454206.141104.95830HepG2PARN
PNPOENSG00000108439.5698.976401022.40400-0.548607.379706.21770HepG2PPIL4
PNPOENSG00000108439.51853.016601437.989100.365705.346404.30660HepG2PRPF4
PNPOENSG00000108439.52216.094101640.852500.433507.808706.98370HepG2PTBP1
PNPOENSG00000108439.52227.312701400.738400.6690010.547909.48420HepG2PUF60
PNPOENSG00000108439.51148.716701486.94020-0.372306.156205.34470HepG2PUM1
PNPOENSG00000108439.51106.219101485.85740-0.425704.882804.00500HepG2PUM2
PNPOENSG00000108439.52425.482901182.763601.0360044.3511042.48730HepG2PUS1
PNPOENSG00000108439.52532.513401777.044100.511008.623607.61520HepG2QKI
PNPOENSG00000108439.5712.325001148.96980-0.689703.873703.04330HepG2RAVER1
PNPOENSG00000108439.52027.073401443.434400.489804.994203.88490HepG2RBM15
PNPOENSG00000108439.5967.06560435.125701.152103.706801.58890HepG2RBM17
PNPOENSG00000108439.5808.729301612.79670-0.9958020.2480018.53760HepG2RBM25
PNPOENSG00000108439.5819.356801195.17750-0.544704.938003.59520HepG2RBM27
PNPOENSG00000108439.51069.521801826.09580-0.7718019.1684017.99500HepG2NELFE
PNPOENSG00000108439.51078.011201700.78810-0.6578014.3823013.14660HepG2RECQL
PNPOENSG00000108439.52275.515101522.669200.579507.348206.31390HepG2RPLP0
PNPOENSG00000108439.51040.18210791.434600.394203.249802.59060HepG2RPS19
PNPOENSG00000108439.5821.96870602.623900.447702.378801.63380HepG2RPS3A
PNPOENSG00000108439.5476.03960815.92540-0.777406.652805.49040HepG2RRP9
PNPOENSG00000108439.51309.499601020.836800.359204.967704.14740HepG2SAFB2
PNPOENSG00000108439.51054.07430794.253400.408203.039002.05180HepG2SERBP1
PNPOENSG00000108439.51790.803701293.727700.469004.793403.88670HepG2SF3B1
PNPOENSG00000108439.51296.524401708.30580-0.397905.915405.10640HepG2SF3B4
PNPOENSG00000108439.51157.24790375.792401.622607.634105.22920HepG2SNRNP200
PNPOENSG00000108439.51099.193001736.17130-0.6595015.5462014.61180HepG2SRFBP1
PNPOENSG00000108439.51273.137901783.11510-0.486009.089608.34330HepG2SRSF1
PNPOENSG00000108439.51609.698601383.018600.218902.198701.63350HepG2SRSF5
PNPOENSG00000108439.52448.108401507.411300.6995020.9367019.81260HepG2SSB
PNPOENSG00000108439.51427.259601034.898100.463703.322201.97310HepG2STAU1
PNPOENSG00000108439.51232.868001572.87870-0.351405.199304.39280HepG2SUCLG1
PNPOENSG00000108439.51359.710701046.242100.378003.565402.50690HepG2SUPT6H
PNPOENSG00000108439.51767.943201273.881700.472704.763603.84720HepG2TARDBP
PNPOENSG00000108439.5460.06040713.40990-0.632904.648903.40510HepG2TFIP11
PNPOENSG00000108439.51523.569201113.925900.451705.698305.03080HepG2TIAL1
PNPOENSG00000108439.51041.477301368.45320-0.393903.799802.76020HepG2TUFM
PNPOENSG00000108439.51048.898701325.51320-0.337702.518701.91750HepG2U2AF1
PNPOENSG00000108439.51982.259701448.480300.452503.599702.63880HepG2UBE2L3
PNPOENSG00000108439.5433.70010628.75780-0.535803.714102.83580HepG2UCHL5
PNPOENSG00000108439.51809.715801270.651300.5101010.505309.30230HepG2UPF1
PNPOENSG00000108439.5953.449301226.76640-0.363604.366703.64200HepG2UTP3
PNPOENSG00000108439.51887.757101397.475500.433809.443708.58560HepG2ZNF622
PNPOENSG00000108439.5315.41070811.68330-1.3637014.9121013.70120K562AQR
PNPOENSG00000108439.5493.63270653.10400-0.403902.427701.61610K562BOP1
PNPOENSG00000108439.5357.61940491.88770-0.459902.873401.56690K562CIRBP
PNPOENSG00000108439.5466.59210694.44970-0.573705.395104.30780K562CPSF6
PNPOENSG00000108439.51070.959201330.56540-0.313102.368701.46780K562CELF1
PNPOENSG00000108439.5511.18390640.29800-0.324902.429201.61610K562DKC1
PNPOENSG00000108439.5394.31890555.44040-0.494303.379702.36690K562EFTUD2
PNPOENSG00000108439.5328.08220456.12570-0.475402.548801.47360K562FKBP4
PNPOENSG00000108439.5416.96120598.86380-0.522303.466402.43550K562FTO
PNPOENSG00000108439.5153.37380294.45650-0.941007.852305.47170K562FUS
PNPOENSG00000108439.5505.38190377.222600.421902.971802.34800K562FXR1
PNPOENSG00000108439.5486.35950663.03880-0.447102.728001.93890K562GPKOW
PNPOENSG00000108439.5270.60780481.79020-0.832204.118201.69930K562HLTF
PNPOENSG00000108439.5537.83410725.29570-0.431403.512702.29550K562HNRNPA1
PNPOENSG00000108439.5407.67290525.56010-0.366402.037301.51420K562HNRNPC
PNPOENSG00000108439.5517.73250731.85710-0.499404.320901.96820K562HNRNPH1
PNPOENSG00000108439.5650.25000803.25780-0.304902.267301.45860K562HNRNPU
PNPOENSG00000108439.51525.769201146.612400.412103.599302.69570K562HSPD1
PNPOENSG00000108439.5478.52990737.96170-0.624904.669502.31400K562IGF2BP1
PNPOENSG00000108439.5222.30180483.40820-1.120705.050302.16440K562LARP4
PNPOENSG00000108439.5837.15090678.624800.302801.982801.30300K562POLR2G
PNPOENSG00000108439.5412.56980540.51010-0.389702.127001.46580K562PRPF8
PNPOENSG00000108439.5729.09850468.639000.637506.994605.97610K562PTBP1
PNPOENSG00000108439.5497.81960354.088500.491402.220401.33280K562RPS3
PNPOENSG00000108439.51045.95150604.713400.7904010.720908.67870K562SAFB
PNPOENSG00000108439.5400.33150630.53620-0.655404.648503.36740K562SF3B1
PNPOENSG00000108439.5300.70450459.43880-0.611504.645303.73310K562SRSF1
PNPOENSG00000108439.5521.14090658.28600-0.337002.716301.56230K562SRSF7
PNPOENSG00000108439.5793.502101030.34640-0.376803.062401.47710K562SUCLG1
PNPOENSG00000108439.51152.96990680.697000.7602012.0280010.31420K562SYNCRIP
PNPOENSG00000108439.5191.82380298.37780-0.637404.048303.07700K562U2AF2
PNPOENSG00000108439.5410.20570553.80640-0.433002.613301.62590K562UCHL5
PNPOENSG00000108439.5657.03920961.46690-0.549305.262803.47920K562WRN
PNPOENSG00000108439.5596.93240914.50060-0.615405.215503.96920K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PNPO is not available on ENCORE database.





3 RBPs can affect the splicing of PNPO :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPNPOENSG00000108439.5chr17+4602292446022978460219814602208146023226460233550.060000.000510.03005includedHepG2PTBP1
SEPNPOENSG00000108439.5chr17+460229244602297846021981460220814602368846023759-0.460000.000320.00885excludedK562U2AF1
A5SSPNPOENSG00000108439.5chr17+4601893646019417460189364601917946020671460207960.145000.000030.00194longerHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PNPO is not avaliable on ENCORE database.