PLK3

General Information

Gene Name       : PLK3
Gene ID             : ENSG00000173846.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PLK3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PLK3ENSG00000173846.123.426.304.86ENCSR000AEF
HepG2PLK3ENSG00000173846.129.915.907.91ENCSR985KAT
K562PLK3ENSG00000173846.1210.158.209.18ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PLK3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PLK3 RNA is bound by 8 proteins.  







eCLIP assay for PLK3 is not avaliable on ENCORE database.





8 proteins are bound to PLK3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr14527104545271137+CDS,intron-Proximal5.287885.58036HepG2EFTUD2
chr14526747345267535+CDS,intron-Proximal4.7773911.56048K562EFTUD2
chr14526881945268863+CDS,intron-Proximal4.512476.81564HepG2PRPF8
chr14527087545270961+CDS,intron-Proximal3.842334.52312K562AQR
chr14526995645270029+CDS,intron-Proximal4.930434.90235K562SF3B4
chr14526843445268514+CDS3.863377.91657HepG2PPIG
chr14526927545269319+CDS3.727945.24452HepG2PPIG
chr14526634145266399+CDS,intron-Proximal4.080487.13970HepG2PRPF8
chr14527103345271113+CDS,intron-Proximal4.224877.26133HepG2PRPF8
chr14527087145270974+CDS,intron-Proximal4.450195.32775HepG2SF3B4
chr14526756045267603+CDS4.305065.80295HepG2PPIG
chr14526755845267611+CDS,intron-Proximal5.323075.96317HepG2EFTUD2
chr14526935945269403+CDS,intron-Proximal3.391227.29769HepG2PRPF8
chr14526931945269370+CDS,intron-Proximal3.578995.58370HepG2PPIG
chr14526935345269411+CDS,intron-Proximal4.603314.65563K562AQR
chr14526974845269844+CDS,intron-Proximal5.0305910.06330HepG2EFTUD2
chr14526995645270038+CDS,intron-Proximal3.440513.37120HepG2SF3B4
chr14527084645270952+CDS,intron-Proximal4.095253.83958HepG2QKI
chr14526975545269861+CDS,intron-Proximal5.041088.80869K562EFTUD2
chr14526770145267765+intron-Distal,intron-Proximal5.621317.23906K562EFTUD2
chr14526766345267814+intron-Distal,intron-Proximal3.967673.60944K562TARDBP
chr14526975545269817+intron-Proximal4.383743.82050HepG2SF3B4
chr14526638745266476+intron-Proximal4.752445.51215K562RBM15
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PLK3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PLK3 is not available on ENCORE database.

  • 120 RBPs can affect the levels of PLK3.  








The Knockdown/knockout RNA-Seq assay for PLK3 is not available on ENCORE database.





120 RBPs can affect the gene expression of PLK3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PLK3ENSG00000173846.8582.72330170.899701.7696039.6488038.00660HepG2ACO1
PLK3ENSG00000173846.8464.65470172.216301.4318013.0042011.93920HepG2AKAP1
PLK3ENSG00000173846.8615.58440257.010201.2600014.0257011.89600HepG2AKAP8
PLK3ENSG00000173846.8633.12260255.237601.3105024.4566022.78700HepG2AUH
PLK3ENSG00000173846.8354.63820125.174201.5023011.059909.12480HepG2BCCIP
PLK3ENSG00000173846.8850.29110171.277502.3115054.0983052.13260HepG2BOP1
PLK3ENSG00000173846.8184.6234099.108800.897404.588403.62490HepG2CALR
PLK3ENSG00000173846.8274.84140170.895200.685404.834104.00140HepG2CKAP4
PLK3ENSG00000173846.8222.49840157.243800.500701.986701.39350HepG2CPSF6
PLK3ENSG00000173846.8323.61440163.852900.981806.909405.23430HepG2CPSF7
PLK3ENSG00000173846.8348.32950142.288101.2915014.5275013.28150HepG2CELF1
PLK3ENSG00000173846.8242.93370164.952200.558402.181001.61840HepG2DDX3X
PLK3ENSG00000173846.8315.02050123.079901.355808.728907.43840HepG2DDX55
PLK3ENSG00000173846.8715.20470141.739802.3350038.8312036.91410HepG2DDX6
PLK3ENSG00000173846.8214.8558096.489501.154808.392407.22090HepG2DNAJC21
PLK3ENSG00000173846.8186.1999095.643300.961003.461402.74670HepG2DNAJC2
PLK3ENSG00000173846.8143.6724083.393400.784702.882101.75210HepG2EFTUD2
PLK3ENSG00000173846.8221.83170136.215800.703502.985002.36930HepG2EIF2S1
PLK3ENSG00000173846.8182.5204081.201001.168405.789004.51610HepG2EIF3D
PLK3ENSG00000173846.8218.66920150.514100.538801.941101.40170HepG2EIF4A3
PLK3ENSG00000173846.8342.87520146.585501.225807.873806.74320HepG2EIF4B
PLK3ENSG00000173846.8267.12120150.943200.823405.499904.38620HepG2EIF4G1
PLK3ENSG00000173846.8517.39090293.030200.820109.658008.64420HepG2ETF1
PLK3ENSG00000173846.8507.97840201.009101.3374011.6495010.22540HepG2FIP1L1
PLK3ENSG00000173846.8177.1817085.891301.044504.716603.28460HepG2FUS
PLK3ENSG00000173846.8235.94760151.924000.635002.736702.04930HepG2FXR1
PLK3ENSG00000173846.8297.02680140.899401.075807.402306.33820HepG2G3BP1
PLK3ENSG00000173846.8186.5633097.366400.938103.778102.58260HepG2GNB2L1
PLK3ENSG00000173846.8307.38670163.180100.913508.443906.85250HepG2HDGF
PLK3ENSG00000173846.8307.03560193.064500.669203.189701.72550HepG2HNRNPA0
PLK3ENSG00000173846.8285.30920188.509500.597802.745201.34900HepG2HNRNPAB
PLK3ENSG00000173846.8171.89000108.357000.665602.372301.72490HepG2HNRNPC
PLK3ENSG00000173846.8339.54860258.058100.395802.474701.79420HepG2HNRNPF
PLK3ENSG00000173846.8229.99500142.749100.688003.028802.29930HepG2HNRNPK
PLK3ENSG00000173846.8212.46850139.410800.607803.015202.31440HepG2HNRNPL
PLK3ENSG00000173846.8205.67690138.630600.569002.181201.33680HepG2HNRNPM
PLK3ENSG00000173846.8226.31120107.640401.072006.386605.49640HepG2HNRNPU
PLK3ENSG00000173846.8316.97430143.209601.146108.501507.38760HepG2IGF2BP2
PLK3ENSG00000173846.8354.87590134.442501.400205.097303.78050HepG2IGF2BP3
PLK3ENSG00000173846.8169.40580109.950800.623502.754302.02360HepG2ILF2
PLK3ENSG00000173846.8429.99330222.390100.951106.243004.18980HepG2ILF3
PLK3ENSG00000173846.8330.54390217.529200.603503.018401.76410HepG2KHDRBS1
PLK3ENSG00000173846.8577.93220206.230201.4865015.8814013.92440HepG2LARP4
PLK3ENSG00000173846.8192.0722095.454501.008704.629203.16160HepG2LARP7
PLK3ENSG00000173846.8325.15790151.977401.097207.918006.81980HepG2MAGOH
PLK3ENSG00000173846.8322.31510152.817901.076606.962805.99540HepG2MATR3
PLK3ENSG00000173846.8201.5543084.989301.245704.696003.34620HepG2METAP2
PLK3ENSG00000173846.8325.66900162.593001.002007.242205.99110HepG2MSI2
PLK3ENSG00000173846.8270.80390156.409500.791804.053903.29230HepG2NCBP2
PLK3ENSG00000173846.8283.83980151.743500.903306.570905.40050HepG2NOL12
PLK3ENSG00000173846.8255.20390113.057901.174504.938803.45610HepG2NONO
PLK3ENSG00000173846.887.88480150.83120-0.779202.487701.77770HepG2NSUN2
PLK3ENSG00000173846.8710.91440208.529601.7693012.9218010.96500HepG2PABPC1
PLK3ENSG00000173846.8303.30520139.255401.122908.127006.90570HepG2PABPC4
PLK3ENSG00000173846.8205.01040106.543200.944205.921204.75300HepG2PARN
PLK3ENSG00000173846.8287.99800116.807501.3018013.0835011.91710HepG2PCBP1
PLK3ENSG00000173846.8137.1419081.291800.754402.515601.52560HepG2PCBP2
PLK3ENSG00000173846.8390.19790204.583100.931405.480903.36480HepG2PNPT1
PLK3ENSG00000173846.8366.63550118.858701.6250015.8385014.73500HepG2PTBP1
PLK3ENSG00000173846.8397.89030153.744601.3717019.8254018.53240HepG2PUM1
PLK3ENSG00000173846.8528.70780153.639701.7828012.0491010.70560HepG2PUM2
PLK3ENSG00000173846.8285.73170128.721101.150309.214708.17310HepG2QKI
PLK3ENSG00000173846.8250.1791078.398301.674009.389108.14490HepG2RAVER1
PLK3ENSG00000173846.8389.81380200.408400.959706.419005.18010HepG2RBM15
PLK3ENSG00000173846.8894.55970244.922501.8688044.0311042.43900HepG2RBM22
PLK3ENSG00000173846.8292.10110116.824901.3220011.6536010.33040HepG2RBM25
PLK3ENSG00000173846.8247.62240115.113901.105005.671704.23740HepG2RBM27
PLK3ENSG00000173846.8451.18600277.954800.698805.658304.73290HepG2RPLP0
PLK3ENSG00000173846.8130.0804077.102600.754502.343401.47300HepG2RPS10
PLK3ENSG00000173846.8249.4953079.005301.6589013.9817012.73860HepG2RPS19
PLK3ENSG00000173846.8271.88120106.145901.356808.898807.52550HepG2RPS2
PLK3ENSG00000173846.8236.93500108.373001.128405.494603.96520HepG2RPS5
PLK3ENSG00000173846.8264.2910093.876701.493209.680308.33850HepG2RRP9
PLK3ENSG00000173846.8163.2999095.857400.768503.698602.97280HepG2SAFB2
PLK3ENSG00000173846.8552.42590193.625401.5124013.8160012.24530HepG2SF3A3
PLK3ENSG00000173846.8343.03610123.742401.4709016.6082015.34470HepG2SF3B4
PLK3ENSG00000173846.8268.36020122.974501.125702.746801.30840HepG2SFPQ
PLK3ENSG00000173846.8286.09530111.784101.3557014.6114013.31580HepG2SMN1
PLK3ENSG00000173846.8269.8986080.205601.7505014.8469012.58980HepG2SMNDC1
PLK3ENSG00000173846.8314.79790187.348400.748603.196602.35470HepG2SNRNP70
PLK3ENSG00000173846.8708.64990276.637101.3570029.1773027.99840HepG2SRFBP1
PLK3ENSG00000173846.8195.98820129.162200.601502.578902.11820HepG2SRSF1
PLK3ENSG00000173846.8507.36640142.996401.8269034.8772033.00730HepG2SRSF5
PLK3ENSG00000173846.8393.81320253.525000.635305.697004.75550HepG2SRSF7
PLK3ENSG00000173846.8312.41160105.082101.5718019.8159018.58480HepG2SRSF9
PLK3ENSG00000173846.8153.97630240.19720-0.641503.615403.04590HepG2SSB
PLK3ENSG00000173846.8264.68670134.177700.980005.285703.62930HepG2STAU1
PLK3ENSG00000173846.8343.64640199.461800.784704.820303.33030HepG2STIP1
PLK3ENSG00000173846.8171.1768073.278801.223904.835003.23940HepG2SUB1
PLK3ENSG00000173846.8431.41270162.638501.4073020.2220018.78860HepG2SUCLG1
PLK3ENSG00000173846.8309.61670122.512201.337508.388507.31580HepG2SUPV3L1
PLK3ENSG00000173846.8238.38030165.791800.523802.148301.49760HepG2TARDBP
PLK3ENSG00000173846.8227.6809082.108401.471309.439307.82070HepG2TFIP11
PLK3ENSG00000173846.8191.02710106.675700.840404.476303.42150HepG2TIA1
PLK3ENSG00000173846.8237.15210104.585601.181008.875308.07160HepG2TIAL1
PLK3ENSG00000173846.8209.33810105.528300.988106.941706.11840HepG2TRIM56
PLK3ENSG00000173846.8118.6993064.528300.879203.058501.42090HepG2TROVE2
PLK3ENSG00000173846.8249.12350141.485400.816104.523603.37410HepG2TUFM
PLK3ENSG00000173846.8311.68730171.898600.858404.741403.93160HepG2U2AF1
PLK3ENSG00000173846.8452.94610149.747301.596704.556903.46440HepG2UBE2L3
PLK3ENSG00000173846.8224.1162072.363601.6308012.4966010.90750HepG2UCHL5
PLK3ENSG00000173846.8267.09780171.716100.637203.833703.03220HepG2UPF1
PLK3ENSG00000173846.8191.23580112.152300.769802.202301.31190HepG2UPF2
PLK3ENSG00000173846.8400.19290165.785201.2713016.0313014.76390HepG2UTP3
PLK3ENSG00000173846.8184.5440086.266201.097005.304503.86140HepG2XRCC6
PLK3ENSG00000173846.8272.81980162.337000.748905.345504.46170HepG2ZC3H8
PLK3ENSG00000173846.8512.89240188.854901.4413027.5288026.25910HepG2ZNF622
PLK3ENSG00000173846.8300.68930433.12450-0.526503.495102.39600K562CELF1
PLK3ENSG00000173846.8248.00660148.844000.736504.338402.99060K562DDX3X
PLK3ENSG00000173846.8206.65900119.737500.787303.727202.65600K562EFTUD2
PLK3ENSG00000173846.8128.4569077.470800.729502.420101.67370K562EIF3G
PLK3ENSG00000173846.8239.34680140.030300.773305.150903.50500K562EIF4B
PLK3ENSG00000173846.8208.54570128.099600.703003.053902.15120K562FMR1
PLK3ENSG00000173846.823.1265082.30220-1.831406.206605.05400K562G3BP2
PLK3ENSG00000173846.8119.88800206.10160-0.781704.158402.84420K562HNRNPA1
PLK3ENSG00000173846.8202.95780123.854600.712403.702002.28120K562IGF2BP3
PLK3ENSG00000173846.8512.89030375.439600.450002.595001.50340K562MSI2
PLK3ENSG00000173846.8193.09980277.66560-0.524003.058102.27670K562NSUN2
PLK3ENSG00000173846.8237.91980147.494900.689703.167601.60980K562NUSAP1
PLK3ENSG00000173846.8390.63480225.879300.790205.690603.33220K562PKM
PLK3ENSG00000173846.8191.23390116.518300.714702.803502.04920K562PRPF8
PLK3ENSG00000173846.8274.63410134.273101.032206.837805.30530K562PSIP1
PLK3ENSG00000173846.8284.40080124.295301.1941010.954309.69580K562PTBP1
PLK3ENSG00000173846.8269.94020384.30790-0.509602.649501.85190K562PUF60
PLK3ENSG00000173846.8388.88550276.419800.492402.565802.03860K562PUS1
PLK3ENSG00000173846.8260.95960119.141101.131104.326903.24790K562RBM22
PLK3ENSG00000173846.8158.8633085.582900.892302.528301.71270K562SF3B4
PLK3ENSG00000173846.8194.30590121.859700.673002.990002.25810K562SRSF1
PLK3ENSG00000173846.835.1310080.78960-1.201403.086801.51540K562TAF15
PLK3ENSG00000173846.8204.11840123.310900.727003.467802.67220K562TARDBP
PLK3ENSG00000173846.8183.22090118.952300.623102.589201.80010K562TIA1
PLK3ENSG00000173846.8196.40270116.772900.750003.371902.14350K562TRA2A
PLK3ENSG00000173846.8388.63540276.666200.490203.453002.02660K562TROVE2
PLK3ENSG00000173846.8169.59050261.98410-0.627403.988902.98570K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PLK3 is not available on ENCORE database.





16 RBPs can affect the splicing of PLK3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSPLK3ENSG00000173846.8chr1+4526981745269918452698344526991845269602452696960.234000.000150.00123longerK562AQR
RIPLK3ENSG00000173846.8chr1+452686264526906345268626452688254526893945269063-0.105000.001640.07850excludedHepG2TBRG4
RIPLK3ENSG00000173846.8chr1+4526927145269696452692714526936345269602452696960.203000.000000.00001includedK562PUS1
RIPLK3ENSG00000173846.8chr1+4526862645269063452686264526882545268939452690630.173000.000020.00019includedK562PUS1
RIPLK3ENSG00000173846.8chr1+4527001045270451452700104527017345270321452704510.139000.004340.02756includedK562PUS1
RIPLK3ENSG00000173846.8chr1+4526927145269696452692714526936345269602452696960.145000.009720.08373includedHepG2SF3A3
RIPLK3ENSG00000173846.8chr1+452700104527045145270010452701734527032145270451-0.133000.001450.01810excludedHepG2SF3A3
RIPLK3ENSG00000173846.8chr1+4526927145269696452692714526936345269602452696960.329000.002100.02702includedHepG2PRPF8
RIPLK3ENSG00000173846.8chr1+4526862645269063452686264526882545268939452690630.184000.000210.04726includedK562LARP7
RIPLK3ENSG00000173846.8chr1+4526927145269696452692714526936345269602452696960.135000.001640.02082includedK562AGGF1
RIPLK3ENSG00000173846.8chr1+452686264526906345268626452688254526893945269063-0.131000.000000.00172excludedHepG2NKRF
RIPLK3ENSG00000173846.8chr1+4526927145269696452692714526936345269602452696960.083000.004880.04308includedK562AKAP8L
RIPLK3ENSG00000173846.8chr1+4526862645269063452686264526882545268939452690630.215000.009740.07543includedHepG2TAF15
RIPLK3ENSG00000173846.8chr1+4527001045270451452700104527017345270321452704510.308000.000170.00260includedHepG2U2AF1
RIPLK3ENSG00000173846.8chr1+4526927145269696452692714526936345269602452696960.134000.000400.00587includedK562RBM15
RIPLK3ENSG00000173846.8chr1+4527001045270451452700104527017345270321452704510.129000.005990.05779includedHepG2NCBP2
RIPLK3ENSG00000173846.8chr1+4527001045270451452700104527017345270321452704510.126000.007370.06054includedHepG2RBM22
RIPLK3ENSG00000173846.8chr1+4526927145269696452692714526936345269602452696960.123000.002160.02733includedK562UTP18
RIPLK3ENSG00000173846.8chr1+452686264526906345268626452688254526893945269063-0.129000.000000.00214excludedHepG2SUGP2
RIPLK3ENSG00000173846.8chr1+4526927145269696452692714526936345269602452696960.113000.001350.00886includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PLK3 is not avaliable on ENCORE database.