PIAS2

General Information

Gene Name       : PIAS2
Gene ID             : ENSG00000078043.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PIAS2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PIAS2ENSG00000078043.1520.3118.9719.64ENCSR000AEF
HepG2PIAS2ENSG00000078043.154.798.176.48ENCSR985KAT
K562PIAS2ENSG00000078043.1511.5012.8112.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PIAS2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PIAS2 RNA is bound by 15 proteins.  







eCLIP assay for PIAS2 is not avaliable on ENCORE database.





15 proteins are bound to PIAS2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr184442666944426738-3'-UTR,CDS,intron-Distal,intron-Proximal3.078283.90681K562DDX24
chr184443552744435535-3'-UTR,CDS,intron-Distal,intron-Proximal3.9346711.74065HepG2BCLAF1
chr184444413444444169-3'-UTR,CDS,intron-Distal3.259998.54277HepG2BCLAF1
chr184440969344409818-3'-UTR,CDS,intron-Distal,intron-Proximal3.2608211.83387HepG2BCLAF1
chr184442666844426697-3'-UTR,CDS,intron-Distal,intron-Proximal3.761625.97823HepG2BCLAF1
chr184439833044398383-3'-UTR,CDS,intron-Distal3.376035.35431HepG2BCLAF1
chr184440801544408095-3'-UTR,CDS,intron-Distal,intron-Proximal3.9077415.82151HepG2BCLAF1
chr184443553544435580-3'-UTR,CDS,intron-Distal,intron-Proximal3.6015416.34425HepG2BCLAF1
chr184440802244408091-3'-UTR,CDS,intron-Distal3.520763.85127HepG2GRWD1
chr184443534844435398-3'-UTR,CDS,intron-Distal5.0830221.23661HepG2BCLAF1
chr184443535844435398-3'-UTR,CDS,intron-Distal3.070784.39623HepG2PPIG
chr184442669744426751-3'-UTR,CDS,intron-Distal3.365275.79905HepG2BCLAF1
chr184443552244435557-3'-UTR,CDS,intron-Distal,intron-Proximal3.239304.51003HepG2PPIG
chr184442675744426805-3'-UTR,CDS,intron-Distal,intron-Proximal3.138087.61291HepG2BCLAF1
chr184442406744424090-3'-UTR,CDS,intron-Distal3.691536.97808HepG2BCLAF1
chr184441631844416435-3'-UTR,CDS,intron-Distal,intron-Proximal3.8147217.69105HepG2BCLAF1
chr184440789644408014-3'-UTR,CDS,intron-Distal,intron-Proximal4.5406010.04397HepG2GRWD1
chr184439524844395307-3'-UTR,CDS,intron-Distal,intron-Proximal3.621704.97118HepG2U2AF2
chr184439529944395357-3'-UTR,CDS,intron-Distal,intron-Proximal3.861684.69223K562SF3B4
chr184442469644424798-3'-UTR,CDS,intron-Distal,intron-Proximal4.1427415.37934HepG2BCLAF1
chr184440803444408106-3'-UTR,CDS,intron-Distal,intron-Proximal3.942373.19080K562U2AF2
chr184449731744497412-5'-UTR,intron-Distal,intron-Proximal5.508955.55590HepG2DDX3X
chr184447059744470688-CDS,intron-Distal,intron-Proximal4.136973.54770K562IGF2BP1
chr184447069844470816-CDS,intron-Distal,intron-Proximal4.443484.10924HepG2ZNF800
chr184440632444406417-intron-Distal4.728935.02084HepG2HNRNPM
chr184440123844401364-intron-Distal3.9172910.04211HepG2KHSRP
chr184442632444426438-intron-Distal,intron-Proximal4.125204.07352K562KHSRP
chr184439515544395241-intron-Distal,intron-Proximal4.406004.30850HepG2QKI
chr184440730644407381-intron-Distal,intron-Proximal4.978689.68700K562U2AF2
chr184440762144407697-intron-Distal,intron-Proximal3.230683.81210HepG2KHSRP
chr184440115944401220-intron-Distal4.574006.14841HepG2KHSRP
chr184440782144407896-intron-Distal,intron-Proximal4.040343.07287K562TIA1
chr184440120344401338-intron-Distal3.971558.47371K562KHSRP
chr184440732544407385-intron-Distal,intron-Proximal5.423736.50173HepG2U2AF2
chr184440243844402570-intron-Distal3.935097.67375HepG2U2AF2
chr184440731244407391-intron-Distal,intron-Proximal3.601904.64851K562U2AF1
chr184444990544449979-intron-Distal4.207253.54208HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PIAS2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PIAS2 is not available on ENCORE database.

  • 110 RBPs can affect the levels of PIAS2.  








The Knockdown/knockout RNA-Seq assay for PIAS2 is not available on ENCORE database.





110 RBPs can affect the gene expression of PIAS2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PIAS2ENSG00000078043.11522.85140799.70330-0.613104.901803.68240HepG2ABCF1
PIAS2ENSG00000078043.11567.46480772.48000-0.445005.152104.37350HepG2ACO1
PIAS2ENSG00000078043.11490.61750658.88740-0.425402.539901.78600HepG2ASCC1
PIAS2ENSG00000078043.11994.47570743.868500.418804.822403.95750HepG2AUH
PIAS2ENSG00000078043.11262.03690446.19610-0.767904.424203.23790HepG2BCCIP
PIAS2ENSG00000078043.11790.22420598.954300.399702.685301.47370HepG2BUD13
PIAS2ENSG00000078043.11398.48980772.27320-0.9546019.5077018.09590HepG2CKAP4
PIAS2ENSG00000078043.11474.58940714.41540-0.590108.482307.16350HepG2DDX19B
PIAS2ENSG00000078043.11400.38420603.74930-0.592604.845003.97450HepG2DDX21
PIAS2ENSG00000078043.11454.52900591.00790-0.378802.432801.58140HepG2DDX24
PIAS2ENSG00000078043.11287.87110438.68960-0.607802.752301.98090HepG2DDX55
PIAS2ENSG00000078043.11286.49910739.04400-1.3671029.0398027.43670HepG2DKC1
PIAS2ENSG00000078043.11256.18490632.51060-1.3039015.8725013.94390HepG2EEF2
PIAS2ENSG00000078043.11376.52690527.31180-0.485902.374801.35020HepG2EFTUD2
PIAS2ENSG00000078043.11906.09690629.915900.524403.975203.27280HepG2EIF2S1
PIAS2ENSG00000078043.11471.96400606.45310-0.361702.625001.49050HepG2EIF2S2
PIAS2ENSG00000078043.11359.32810513.46950-0.515002.842401.92850HepG2EIF3D
PIAS2ENSG00000078043.11361.14680570.27230-0.659106.147204.62930HepG2EIF3G
PIAS2ENSG00000078043.11377.52570696.09700-0.882707.960906.87950HepG2EIF4A3
PIAS2ENSG00000078043.11508.27340677.81320-0.415301.886101.31060HepG2EIF4B
PIAS2ENSG00000078043.11581.81240853.98120-0.553703.756803.07410HepG2ETF1
PIAS2ENSG00000078043.11449.93950754.81640-0.746408.710207.24330HepG2EWSR1
PIAS2ENSG00000078043.11736.94970575.452800.356802.458701.37720HepG2FASTKD2
PIAS2ENSG00000078043.11611.69370807.45560-0.400602.237701.54140HepG2FIP1L1
PIAS2ENSG00000078043.11514.96090365.160500.495802.898301.59990HepG2FKBP4
PIAS2ENSG00000078043.11676.83730388.973000.799008.466207.12940HepG2FUBP3
PIAS2ENSG00000078043.11534.78510814.80220-0.607503.791402.48880HepG2FUS
PIAS2ENSG00000078043.11312.35460457.18180-0.549603.685602.63810HepG2GEMIN5
PIAS2ENSG00000078043.11438.88330601.89340-0.455702.328901.39760HepG2GNB2L1
PIAS2ENSG00000078043.11147.60630557.32400-1.9168025.7880024.05690HepG2GPKOW
PIAS2ENSG00000078043.11221.41260591.95540-1.4188019.3813017.92540HepG2HNRNPA1
PIAS2ENSG00000078043.11339.93830658.42810-0.9538010.615909.33410HepG2HNRNPC
PIAS2ENSG00000078043.11413.70750556.96340-0.429003.083102.08140HepG2HNRNPM
PIAS2ENSG00000078043.11392.41670654.07590-0.737108.228107.22360HepG2HNRNPU
PIAS2ENSG00000078043.11400.43130683.08950-0.770504.357502.80680HepG2HSPD1
PIAS2ENSG00000078043.11439.83900662.27520-0.590504.422903.58500HepG2IGF2BP2
PIAS2ENSG00000078043.11592.948301041.72960-0.813007.257405.90000HepG2LARP4
PIAS2ENSG00000078043.11400.09050619.21420-0.630103.796702.37360HepG2LIN28B
PIAS2ENSG00000078043.11362.96710702.68150-0.953009.835208.61890HepG2MAGOH
PIAS2ENSG00000078043.11356.16440537.40050-0.593502.626701.60060HepG2METAP2
PIAS2ENSG00000078043.11720.94140548.608300.394002.546801.38310HepG2NAA15
PIAS2ENSG00000078043.11439.79360723.22830-0.717605.961405.04800HepG2NCBP2
PIAS2ENSG00000078043.11635.21720888.28420-0.483805.003003.98110HepG2NOL12
PIAS2ENSG00000078043.11233.46280402.76160-0.786703.316002.11080HepG2NONO
PIAS2ENSG00000078043.11396.73290644.01930-0.698905.699504.67570HepG2PABPC4
PIAS2ENSG00000078043.11431.84750647.43930-0.584206.598905.37520HepG2PARN
PIAS2ENSG00000078043.11509.81950655.15960-0.361902.946002.32290HepG2PCBP1
PIAS2ENSG00000078043.11508.97420771.36270-0.599803.542202.37420HepG2PCBP2
PIAS2ENSG00000078043.11285.81790424.62440-0.571104.186102.66440HepG2PKM
PIAS2ENSG00000078043.11195.73020338.48890-0.790204.425703.42960HepG2PRPF8
PIAS2ENSG00000078043.11530.06210666.67540-0.330802.627602.09230HepG2PTBP1
PIAS2ENSG00000078043.11314.18000847.95730-1.4324026.2529024.66830HepG2PUF60
PIAS2ENSG00000078043.11453.71120900.15850-0.9884023.1998021.82460HepG2PUM1
PIAS2ENSG00000078043.11450.64550899.49200-0.9971016.3626014.81360HepG2PUM2
PIAS2ENSG00000078043.11541.86900786.81530-0.538107.150506.23850HepG2PUS1
PIAS2ENSG00000078043.11421.53860744.48130-0.820604.615703.71800HepG2RAVER1
PIAS2ENSG00000078043.11521.53710713.78680-0.452702.242701.76270HepG2RBM22
PIAS2ENSG00000078043.11506.04630655.25560-0.372802.434701.79850HepG2RBM25
PIAS2ENSG00000078043.11407.01680710.83230-0.804403.976502.77330HepG2RBM27
PIAS2ENSG00000078043.11376.55830577.22450-0.616303.600302.38980HepG2RCC2
PIAS2ENSG00000078043.11520.93500741.92410-0.510205.089804.39280HepG2NELFE
PIAS2ENSG00000078043.11475.23270691.04060-0.540105.643404.80240HepG2RECQL
PIAS2ENSG00000078043.11309.79430452.35640-0.546103.815903.03390HepG2RPLP0
PIAS2ENSG00000078043.11429.77380731.12800-0.766505.084603.82520HepG2RPS10
PIAS2ENSG00000078043.11204.75740499.61880-1.2869016.3281015.01090HepG2RPS19
PIAS2ENSG00000078043.11307.97460655.62530-1.090107.417106.14720HepG2RPS2
PIAS2ENSG00000078043.11281.74490534.46590-0.923706.950505.69480HepG2RPS3A
PIAS2ENSG00000078043.11410.97900669.19770-0.703405.123403.64690HepG2RPS5
PIAS2ENSG00000078043.11219.06910334.84300-0.612102.757901.97190HepG2RRP9
PIAS2ENSG00000078043.11556.42680809.71530-0.541202.950601.37600HepG2RTF1
PIAS2ENSG00000078043.11417.55570932.77040-1.1596013.1372011.60020HepG2SF3A3
PIAS2ENSG00000078043.11548.06020694.04850-0.340702.553401.98150HepG2SF3B4
PIAS2ENSG00000078043.11355.94520679.29580-0.9324017.2573015.86290HepG2SMN1
PIAS2ENSG00000078043.11523.36810758.56100-0.535403.206702.16730HepG2SMNDC1
PIAS2ENSG00000078043.11417.49500724.45540-0.7951011.2587010.44370HepG2SRSF1
PIAS2ENSG00000078043.11455.02450837.25150-0.8797015.3829014.07520HepG2SRSF5
PIAS2ENSG00000078043.11341.64530700.04550-1.0349010.261809.39410HepG2SSB
PIAS2ENSG00000078043.11326.07860464.94370-0.511802.667201.58900HepG2STIP1
PIAS2ENSG00000078043.11464.33310952.17090-1.0361023.7639022.23380HepG2SUCLG1
PIAS2ENSG00000078043.11157.75820436.73060-1.4690013.4013012.09770HepG2SUPV3L1
PIAS2ENSG00000078043.11508.93160651.22160-0.355702.587802.04400HepG2TAF15
PIAS2ENSG00000078043.11297.00330518.40960-0.803606.754805.68980HepG2TARDBP
PIAS2ENSG00000078043.11343.38720668.19660-0.960404.758803.38990HepG2TBRG4
PIAS2ENSG00000078043.11760.75390598.327900.346402.684301.85970HepG2TIA1
PIAS2ENSG00000078043.11222.35110635.60530-1.5153027.5135026.23940HepG2TIAL1
PIAS2ENSG00000078043.11453.93350747.37730-0.719404.651102.77840HepG2TRA2A
PIAS2ENSG00000078043.11223.81010408.01910-0.866406.082703.84960HepG2TROVE2
PIAS2ENSG00000078043.11426.29920828.44180-0.9585013.5113011.38300HepG2TUFM
PIAS2ENSG00000078043.11436.33220690.59340-0.662406.047905.13610HepG2U2AF1
PIAS2ENSG00000078043.11607.58560850.27920-0.484804.184002.92960HepG2UTP18
PIAS2ENSG00000078043.11549.60770798.65360-0.539206.739505.87380HepG2UTP3
PIAS2ENSG00000078043.11560.63390818.63690-0.546203.217702.07130HepG2XRCC6
PIAS2ENSG00000078043.11308.42130429.91270-0.479102.133601.48990HepG2XRN2
PIAS2ENSG00000078043.11611.32180909.78920-0.573609.524008.66390HepG2ZNF622
PIAS2ENSG00000078043.11533.42600743.62500-0.479302.662101.39490HepG2ZRANB2
PIAS2ENSG00000078043.11805.19380603.445100.416004.252703.57520K562AGGF1
PIAS2ENSG00000078043.11809.24200627.918000.365902.650202.01030K562AKAP8L
PIAS2ENSG00000078043.11485.60600768.43620-0.662105.566104.78430K562AQR
PIAS2ENSG00000078043.11807.21180658.848400.292902.361701.52440K562ATP5C1
PIAS2ENSG00000078043.11675.74180822.41230-0.283402.432201.81570K562DDX47
PIAS2ENSG00000078043.11816.72340570.438300.517703.140102.37810K562G3BP2
PIAS2ENSG00000078043.11336.09530563.34370-0.745106.908605.65240K562GPKOW
PIAS2ENSG00000078043.11298.90900428.46510-0.519503.209102.57270K562HNRNPC
PIAS2ENSG00000078043.11847.50790666.356900.346802.371601.61670K562KIF1C
PIAS2ENSG00000078043.11479.76890635.04780-0.404502.204601.38980K562MATR3
PIAS2ENSG00000078043.11985.79760746.491000.401103.353402.33600K562MBNL1
PIAS2ENSG00000078043.11851.75330523.238000.702904.809003.54350K562NAA15
PIAS2ENSG00000078043.11496.45500618.97210-0.318202.702701.96430K562NSUN2
PIAS2ENSG00000078043.11705.00380528.361300.416002.348901.58280K562PCBP3
PIAS2ENSG00000078043.11516.69690405.261400.350402.209701.49420K562POLR2G
PIAS2ENSG00000078043.11714.09180954.55750-0.418702.810701.98750K562PUF60
PIAS2ENSG00000078043.11976.79590622.679600.649506.736605.93210K562PUS1
PIAS2ENSG00000078043.11788.88640606.742900.378602.188801.65090K562RBM15
PIAS2ENSG00000078043.11448.28150592.94600-0.403502.114801.38480K562RBM22
PIAS2ENSG00000078043.11539.82310406.501200.409102.558001.77090K562SYNCRIP
PIAS2ENSG00000078043.11443.19990571.16720-0.366002.482401.72060K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PIAS2 is not available on ENCORE database.





6 RBPs can affect the splicing of PIAS2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPIAS2ENSG00000078043.11chr18-444834894448359844470542444710174449728444497383-0.500000.000380.00945excludedK562SF3B4
SEPIAS2ENSG00000078043.11chr18-444441264444421144435527444355784447054244471017-0.361000.003440.04663excludedK562PUS1
SEPIAS2ENSG00000078043.11chr18-4448348944483598444705424447101744497284444973830.623000.000160.01517includedHepG2NCBP2
SEPIAS2ENSG00000078043.11chr18-4448348944483598444705424447101744497284444973830.466000.000140.00895includedHepG2MATR3
SEPIAS2ENSG00000078043.11chr18-4448348944483598444705424447101744497284444973830.333000.000170.04442includedK562SBDS
A3SSPIAS2ENSG00000078043.11chr18-4442469644424823444246964442480244426669444268040.081000.019260.09232longerK562AQR
A3SSPIAS2ENSG00000078043.11chr18-4440969644409908444096964440983044416319444164800.086000.006000.03393longerK562AQR
A3SSPIAS2ENSG00000078043.11chr18-4441631944416506444163194441648044424016444240900.222000.000070.00062longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PIAS2 is not avaliable on ENCORE database.