NHP2

General Information

Gene Name       : NHP2
Gene ID             : ENSG00000145912.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: NHP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NHP2ENSG00000145912.829.3166.2547.78ENCSR000AEF
HepG2NHP2ENSG00000145912.8141.9358.44100.19ENCSR985KAT
K562NHP2ENSG00000145912.8225.4696.22160.84ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NHP2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NHP2 RNA is bound by 7 proteins.  







eCLIP assay for NHP2 is not avaliable on ENCORE database.





7 proteins are bound to NHP2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5177576518177576548-3'-UTR,intron-Distal3.573779.84609K562YBX3
chr5177576500177576518-3'-UTR,intron-Distal4.3931810.75300K562YBX3
chr5177576798177576842-3'-UTR,CDS,intron-Distal3.321334.90382K562DDX6
chr5177576725177576800-3'-UTR,CDS,intron-Distal5.7439611.46328HepG2LARP4
chr5177576641177576678-3'-UTR,intron-Distal5.379976.79809K562PABPC4
chr5177576677177576722-3'-UTR,CDS,intron-Distal5.450038.76030HepG2LARP4
chr5177576638177576677-3'-UTR,intron-Distal3.266764.22050HepG2LARP4
chr5177576714177576768-3'-UTR,CDS,intron-Distal4.094886.33786K562PABPC4
chr5177576768177576800-3'-UTR,CDS,intron-Distal4.4427013.67974K562PABPC4
chr5177577886177577937-CDS,intron-Distal,intron-Proximal3.727494.03691K562PUM1
chr5177580756177580786-CDS,intron-Distal3.5239115.66936K562YBX3
chr5177580732177580815-CDS,intron-Distal3.005217.99762K562DDX3X
chr5177577969177577990-CDS,intron-Distal3.3402214.14661K562YBX3
chr5177576833177576839-CDS,intron-Distal3.1893110.79539K562YBX3
chr5177580703177580736-CDS,intron-Distal3.8204316.79105K562YBX3
chr5177577892177577915-CDS,intron-Distal3.0500112.18647K562YBX3
chr5177576803177576840-CDS,intron-Distal3.3494010.50538K562PUM2
chr5177576801177576833-CDS,intron-Distal3.4131912.31703K562YBX3
chr5177577888177577892-CDS,intron-Distal,intron-Proximal3.126748.45630K562YBX3
chr5177576800177576839-CDS,intron-Distal3.7404011.49229K562PABPC4
chr5177577888177577909-CDS,intron-Distal,intron-Proximal3.487576.07797HepG2LARP4
chr5177580669177580732-CDS,intron-Distal,intron-Proximal3.793029.27595K562DDX3X
chr5177577888177577966-CDS,intron-Distal,intron-Proximal3.153475.27768K562DDX6
chr5177580681177580703-CDS,intron-Distal3.9011515.73382K562YBX3
chr5177576800177576840-CDS,intron-Distal3.615916.61899HepG2LARP4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NHP2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NHP2 is not available on ENCORE database.

  • 110 RBPs can affect the levels of NHP2.  








The Knockdown/knockout RNA-Seq assay for NHP2 is not available on ENCORE database.





110 RBPs can affect the gene expression of NHP2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NHP2ENSG00000145912.4460.20730576.98560-0.326302.517201.93250HepG2ACO1
NHP2ENSG00000145912.41516.75640984.203800.623905.243804.54070HepG2AKAP1
NHP2ENSG00000145912.4798.371801006.56740-0.334303.357402.61370HepG2AUH
NHP2ENSG00000145912.4131.18130413.14720-1.6551019.8276018.44650HepG2BOP1
NHP2ENSG00000145912.4560.15450759.42740-0.439102.302401.42110HepG2CCAR1
NHP2ENSG00000145912.4386.34770260.051100.571002.336901.63740HepG2CNOT7
NHP2ENSG00000145912.4160.40130379.28360-1.2416011.3373010.05120HepG2CPSF6
NHP2ENSG00000145912.4320.22880459.62850-0.521403.356202.61410HepG2DDX21
NHP2ENSG00000145912.4312.41480450.02100-0.526503.495802.46140HepG2DDX24
NHP2ENSG00000145912.4390.49370552.02900-0.499404.410203.59120HepG2DKC1
NHP2ENSG00000145912.4283.78040423.45230-0.577402.995801.83550HepG2AGO1
NHP2ENSG00000145912.4552.15550778.41440-0.495502.085101.56270HepG2EIF2S1
NHP2ENSG00000145912.4320.09770434.20440-0.439902.707701.63640HepG2EIF3G
NHP2ENSG00000145912.4538.51430755.63850-0.488705.033303.95910HepG2EIF4G1
NHP2ENSG00000145912.4810.787801155.68190-0.511307.858506.93410HepG2ETF1
NHP2ENSG00000145912.4756.00310563.852800.423003.361302.44110HepG2EWSR1
NHP2ENSG00000145912.4425.01890575.55530-0.437402.042401.35860HepG2FUBP3
NHP2ENSG00000145912.4506.73810855.18910-0.755003.786502.73500HepG2G3BP2
NHP2ENSG00000145912.4297.54450429.92540-0.531002.776902.13480HepG2GPKOW
NHP2ENSG00000145912.4367.00270240.760000.608102.804001.68520HepG2GRSF1
NHP2ENSG00000145912.4476.16440618.96770-0.378402.981502.23910HepG2HNRNPF
NHP2ENSG00000145912.4891.05830697.674300.352904.027103.22610HepG2HNRNPL
NHP2ENSG00000145912.4271.09340410.28780-0.597803.481602.78510HepG2HNRNPLL
NHP2ENSG00000145912.4453.08960609.50920-0.427903.061602.30210HepG2IGF2BP1
NHP2ENSG00000145912.4594.51580356.115000.739302.978201.79990HepG2LARP7
NHP2ENSG00000145912.4404.11290868.60970-1.103906.425105.43600HepG2MAGOH
NHP2ENSG00000145912.4204.09890418.48840-1.035905.930804.48660HepG2MTPAP
NHP2ENSG00000145912.4983.22690759.473500.372403.523402.66350HepG2NOL12
NHP2ENSG00000145912.4198.01220363.81460-0.877605.928304.85850HepG2NSUN2
NHP2ENSG00000145912.4482.47730795.73650-0.721803.961703.10840HepG2PABPC4
NHP2ENSG00000145912.4236.15940418.54300-0.825602.852801.79560HepG2PCBP2
NHP2ENSG00000145912.4370.34580483.28420-0.384002.589601.83960HepG2PRPF4
NHP2ENSG00000145912.4635.14810766.06520-0.270402.101001.61210HepG2PTBP1
NHP2ENSG00000145912.41090.38300769.619600.502508.605407.68210HepG2PUM1
NHP2ENSG00000145912.4452.27910587.70300-0.377903.223402.57070HepG2PUS1
NHP2ENSG00000145912.4589.94770829.62640-0.491904.776803.98910HepG2QKI
NHP2ENSG00000145912.4149.03210403.71560-1.437706.152605.12750HepG2RAVER1
NHP2ENSG00000145912.4551.89870752.95480-0.448203.563402.80490HepG2RBM25
NHP2ENSG00000145912.4606.62270852.54100-0.491005.319104.60820HepG2NELFE
NHP2ENSG00000145912.4524.31170794.05520-0.598807.459706.52010HepG2RECQL
NHP2ENSG00000145912.4404.95220666.73810-0.719403.160202.43730HepG2RPLP0
NHP2ENSG00000145912.4668.95270404.306000.726402.605601.56450HepG2RPS5
NHP2ENSG00000145912.4140.90270439.67720-1.641706.939704.60390HepG2RTF1
NHP2ENSG00000145912.4505.78700344.430800.554205.392004.54580HepG2SAFB2
NHP2ENSG00000145912.4407.61510246.033400.728303.880502.33620HepG2SART3
NHP2ENSG00000145912.4562.72680797.53820-0.503105.599004.80810HepG2SF3B4
NHP2ENSG00000145912.4502.97910401.674000.324402.322301.72540HepG2SMN1
NHP2ENSG00000145912.4657.53260832.47130-0.340303.023802.53460HepG2SRSF1
NHP2ENSG00000145912.4490.58390608.10560-0.309802.093501.47870HepG2SRSF7
NHP2ENSG00000145912.4394.76530677.27190-0.7787011.6038010.61190HepG2SRSF9
NHP2ENSG00000145912.4511.07290947.22800-0.8902018.3429017.27030HepG2SSB
NHP2ENSG00000145912.4336.90190227.331900.567402.802901.69430HepG2STIP1
NHP2ENSG00000145912.4270.08940533.71470-0.982605.177104.29690HepG2SUPV3L1
NHP2ENSG00000145912.4442.30150748.29690-0.7586010.045709.08400HepG2TAF15
NHP2ENSG00000145912.4429.33550687.54130-0.679307.351506.00050HepG2TIA1
NHP2ENSG00000145912.4289.94270375.84340-0.374402.071701.62620HepG2TIAL1
NHP2ENSG00000145912.4566.58120315.226100.845806.978905.76390HepG2UCHL5
NHP2ENSG00000145912.4748.09430484.238500.627408.164107.22330HepG2UTP3
NHP2ENSG00000145912.4352.13550234.034200.589302.877801.75310HepG2XPO5
NHP2ENSG00000145912.4333.00390476.91780-0.518204.573003.74460HepG2ZC3H8
NHP2ENSG00000145912.4266.64750551.62210-1.0487017.7579016.67080HepG2ZNF622
NHP2ENSG00000145912.41907.470901244.985500.6154013.4700012.32030K562AGGF1
NHP2ENSG00000145912.41316.374801060.971100.311103.269501.60960K562AKAP1
NHP2ENSG00000145912.41828.436401367.995200.418404.136502.88080K562AKAP8
NHP2ENSG00000145912.42132.284301295.450100.7188011.133609.70590K562AKAP8L
NHP2ENSG00000145912.41090.403602575.59210-1.2400013.9518012.77780K562AQR
NHP2ENSG00000145912.41671.312801359.213100.298103.034502.07870K562ATP5C1
NHP2ENSG00000145912.4250.05920786.27040-1.6528022.4518020.02120K562BOP1
NHP2ENSG00000145912.4785.359701049.59200-0.418402.781901.36280K562BUD13
NHP2ENSG00000145912.41001.735301744.53060-0.800305.597704.02850K562CNOT7
NHP2ENSG00000145912.4485.94220836.06380-0.782809.155407.71030K562CPSF6
NHP2ENSG00000145912.42412.440903397.76190-0.494108.681606.99410K562CELF1
NHP2ENSG00000145912.41749.493001394.083000.327503.849802.79330K562DKC1
NHP2ENSG00000145912.41541.005801861.75660-0.272803.000302.25650K562EIF2S2
NHP2ENSG00000145912.4874.60170626.753000.480605.227304.14900K562EIF3G
NHP2ENSG00000145912.4754.500301123.06890-0.573906.204304.98400K562EIF4A3
NHP2ENSG00000145912.42390.300802763.03040-0.209102.386801.51070K562EIF4G2
NHP2ENSG00000145912.4810.351901151.83810-0.507303.044501.33340K562ESF1
NHP2ENSG00000145912.4705.77410983.51420-0.478702.653401.55470K562FKBP4
NHP2ENSG00000145912.4427.38290850.61170-0.9930012.3295010.44230K562FMR1
NHP2ENSG00000145912.4448.63470720.94260-0.684305.767304.39420K562FTO
NHP2ENSG00000145912.41494.074401167.939900.355202.258201.70160K562FXR1
NHP2ENSG00000145912.4288.07430582.32090-1.015408.716007.31660K562G3BP2
NHP2ENSG00000145912.41043.795101451.53690-0.475706.582304.86910K562GLRX3
NHP2ENSG00000145912.4543.48380798.26130-0.554603.245902.38810K562GPKOW
NHP2ENSG00000145912.43269.077902480.958600.397904.751303.76130K562GRSF1
NHP2ENSG00000145912.41489.715401838.78430-0.303702.752901.68270K562HNRNPA1
NHP2ENSG00000145912.4464.904001131.55390-1.2833016.2979014.92790K562HNRNPC
NHP2ENSG00000145912.41318.62350891.010900.565404.965203.67560K562HNRNPM
NHP2ENSG00000145912.41614.219302036.39270-0.335203.959002.88420K562HNRNPU
NHP2ENSG00000145912.41492.47180926.081200.688403.530402.31650K562IGF2BP2
NHP2ENSG00000145912.41031.489801592.07320-0.626203.459901.84470K562ILF2
NHP2ENSG00000145912.41738.993801374.844400.338902.992902.13300K562KIF1C
NHP2ENSG00000145912.4358.15750681.54700-0.928207.257605.65930K562KRR1
NHP2ENSG00000145912.41343.57360971.107400.468305.250603.92840K562MATR3
NHP2ENSG00000145912.42005.843601540.166200.381003.895902.78640K562MBNL1
NHP2ENSG00000145912.4474.71850779.18110-0.714905.527204.26260K562METAP2
NHP2ENSG00000145912.42396.656802945.04900-0.297302.510401.43660K562MSI2
NHP2ENSG00000145912.41297.086701695.67870-0.386607.664506.50810K562NSUN2
NHP2ENSG00000145912.4933.839301675.98120-0.843806.807604.88410K562PABPC1
NHP2ENSG00000145912.4922.059101435.25490-0.638406.327905.06820K562PCBP3
NHP2ENSG00000145912.4782.567601100.87580-0.492405.339404.22880K562POLR2G
NHP2ENSG00000145912.41870.882401229.737400.605307.503306.00940K562PPIG
NHP2ENSG00000145912.41375.22880946.681600.538605.202504.17470K562PRPF8
NHP2ENSG00000145912.41492.86530945.447000.6589010.090008.87690K562PTBP1
NHP2ENSG00000145912.42553.536003206.90350-0.328704.273602.92570K562PUM1
NHP2ENSG00000145912.42329.330601284.829100.8582013.9859012.81080K562PUS1
NHP2ENSG00000145912.41882.378301251.791100.588504.657403.90800K562RBM15
NHP2ENSG00000145912.41746.335802352.77830-0.430005.191403.01440K562RBM17
NHP2ENSG00000145912.4759.73130518.513600.551003.771702.58030K562RPS3
NHP2ENSG00000145912.41282.289501673.12330-0.383804.245803.25000K562SF3A3
NHP2ENSG00000145912.4439.75650759.07950-0.787506.879405.30140K562SF3B1
NHP2ENSG00000145912.4623.96000858.31680-0.460102.942401.63660K562SLBP
NHP2ENSG00000145912.41303.233101714.14380-0.395406.977205.56730K562SRPK2
NHP2ENSG00000145912.41488.27090926.872100.6831010.185808.84470K562SRSF1
NHP2ENSG00000145912.41124.36160875.407500.361002.667701.64040K562SRSF5
NHP2ENSG00000145912.4990.667401299.77650-0.391802.706301.47240K562STAU1
NHP2ENSG00000145912.4608.59530916.51580-0.590704.727803.36900K562SUPV3L1
NHP2ENSG00000145912.41346.95410938.014400.521905.062704.08990K562TARDBP
NHP2ENSG00000145912.4444.21540606.69930-0.449703.000301.34200K562TBRG4
NHP2ENSG00000145912.41164.77910904.831500.364203.193102.30460K562TIA1
NHP2ENSG00000145912.4513.89010975.86730-0.925206.961405.42250K562TIAL1
NHP2ENSG00000145912.41260.91910888.004900.505704.915603.38620K562TRA2A
NHP2ENSG00000145912.42826.680603399.23590-0.266102.843101.42040K562UBE2L3
NHP2ENSG00000145912.41224.070101797.95980-0.5547011.6480010.30100K562UPF1
NHP2ENSG00000145912.4992.459901538.46430-0.632409.232307.59200K562WDR3
NHP2ENSG00000145912.41315.430701599.77730-0.282303.749602.77430K562WDR43
NHP2ENSG00000145912.41756.832202901.77950-0.724007.896306.31450K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NHP2 is not available on ENCORE database.





4 RBPs can affect the splicing of NHP2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENHP2ENSG00000145912.4chr5-177577888177577994177576460177576839177580491177580561-0.052000.000780.01666excludedHepG2U2AF1
SENHP2ENSG00000145912.4chr5-177577888177578012177576460177576839177580491177580580-0.094000.000010.00105excludedHepG2AKAP1
SENHP2ENSG00000145912.4chr5-177577957177577994177576460177576839177580491177580561-0.061000.005190.04796excludedK562AQR
SENHP2ENSG00000145912.4chr5-177577888177577994177576460177576839177580491177580561-0.053000.002520.06265excludedHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NHP2 is not avaliable on ENCORE database.