MRPL45

General Information

Gene Name       : MRPL45
Gene ID             : ENSG00000278845.4
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MRPL45)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MRPL45ENSG00000278845.462.2056.1059.15ENCSR000AEF
HepG2MRPL45ENSG00000278845.481.65113.0797.36ENCSR985KAT
K562MRPL45ENSG00000278845.471.7372.0471.89ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MRPL45 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MRPL45 RNA is bound by 11 proteins.  







eCLIP assay for MRPL45 is not avaliable on ENCORE database.





11 proteins are bound to MRPL45 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr173647855036478610+3'-UTR4.061703.02250K562YBX3
chr173647834936478438+3'-UTR,CDS,intron-Proximal4.376004.62947HepG2AQR
chr173647869036478767+3'-UTR4.157173.43811HepG2TIA1
chr173647655136476621+3'-UTR,CDS3.170273.60157HepG2GRWD1
chr173647861036478666+3'-UTR4.4324811.83078K562YBX3
chr173647893836479040+3'-UTR3.709483.99895HepG2SUB1
chr173647869436478748+3'-UTR4.014676.48274K562UPF1
chr173647856136478664+3'-UTR5.6948612.06927HepG2UPF1
chr173647848736478529+3'-UTR3.624074.17155HepG2BCLAF1
chr173645313136453216+5'-UTR,CDS,intron-Proximal3.785205.23852K562DDX3X
chr173645318436453271+CDS,intron-Proximal3.757593.16983HepG2FUS
chr173646593936466040+intron-Distal3.862698.23065HepG2PTBP1
chr173646854236468603+intron-Distal4.266353.95871HepG2ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MRPL45 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MRPL45 is not available on ENCORE database.

  • 115 RBPs can affect the levels of MRPL45.  








The Knockdown/knockout RNA-Seq assay for MRPL45 is not available on ENCORE database.





115 RBPs can affect the gene expression of MRPL45 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MRPL45ENSG00000174100.51478.931903634.60650-1.2972023.8224022.43160HepG2AKAP1
MRPL45ENSG00000174100.51628.053302087.96130-0.358902.415601.43960HepG2AKAP8
MRPL45ENSG00000174100.52160.133202890.06020-0.420008.222107.14310HepG2AUH
MRPL45ENSG00000174100.51039.341801440.79980-0.471203.444302.44490HepG2BCLAF1
MRPL45ENSG00000174100.51245.016301757.40730-0.497305.835404.09190HepG2BUD13
MRPL45ENSG00000174100.51744.043702559.71870-0.553504.381003.13950HepG2CCAR1
MRPL45ENSG00000174100.52216.872402857.19900-0.366103.006702.20150HepG2CIRBP
MRPL45ENSG00000174100.51225.402901655.16090-0.433704.403203.56740HepG2DDX21
MRPL45ENSG00000174100.51961.627701619.448000.276402.354401.51790HepG2DDX24
MRPL45ENSG00000174100.52145.758403481.77000-0.698308.935607.86470HepG2DDX3X
MRPL45ENSG00000174100.51272.556401652.72270-0.377103.746102.18050HepG2DDX52
MRPL45ENSG00000174100.5983.062301630.20480-0.729707.054605.88800HepG2DDX55
MRPL45ENSG00000174100.51242.200102990.69600-1.2676022.5655021.02960HepG2DDX6
MRPL45ENSG00000174100.51301.596001728.73250-0.409407.878406.84860HepG2DNAJC2
MRPL45ENSG00000174100.51478.487501971.95530-0.415503.450002.42720HepG2EEF2
MRPL45ENSG00000174100.51074.967801523.94610-0.503503.536902.27570HepG2AGO1
MRPL45ENSG00000174100.51312.058002875.24340-1.1319021.2448019.71000HepG2EIF2S1
MRPL45ENSG00000174100.51054.623601600.81900-0.602105.258504.04020HepG2EIF3D
MRPL45ENSG00000174100.51904.099503177.58580-0.738808.477507.36100HepG2EIF4A3
MRPL45ENSG00000174100.51935.254603093.62750-0.676805.842904.86840HepG2EIF4B
MRPL45ENSG00000174100.53218.572002659.214200.275303.867602.90750HepG2EIF4G1
MRPL45ENSG00000174100.52154.767203318.15580-0.6228017.3012016.00850HepG2ETF1
MRPL45ENSG00000174100.5974.445301430.67380-0.554007.607105.65370HepG2FAM120A
MRPL45ENSG00000174100.51660.281002368.56720-0.512604.487503.52420HepG2FIP1L1
MRPL45ENSG00000174100.51475.686602021.18100-0.453805.116904.05840HepG2FUBP3
MRPL45ENSG00000174100.51586.203402189.07740-0.464702.884101.74550HepG2FUS
MRPL45ENSG00000174100.51888.938303205.73660-0.7631010.754809.47820HepG2FXR1
MRPL45ENSG00000174100.51453.265102973.95610-1.0331016.7714015.20270HepG2G3BP1
MRPL45ENSG00000174100.52528.433903157.01960-0.320302.443301.60800HepG2G3BP2
MRPL45ENSG00000174100.5961.522001425.33170-0.567905.912704.59930HepG2GEMIN5
MRPL45ENSG00000174100.51188.466101668.55890-0.489503.917502.70270HepG2GNB2L1
MRPL45ENSG00000174100.51327.669401760.82480-0.407404.187403.41480HepG2HNRNPA1
MRPL45ENSG00000174100.52165.981002477.26250-0.193702.172001.33370HepG2HNRNPA2B1
MRPL45ENSG00000174100.51078.727401958.59810-0.8605014.9144013.43180HepG2HNRNPC
MRPL45ENSG00000174100.52157.502602455.60640-0.186702.716702.04890HepG2HNRNPL
MRPL45ENSG00000174100.51559.111901945.64850-0.319504.653703.88460HepG2HNRNPU
MRPL45ENSG00000174100.51704.414803023.02020-0.8267012.3325011.02130HepG2IGF2BP2
MRPL45ENSG00000174100.51701.053402836.73710-0.737802.881901.87870HepG2IGF2BP3
MRPL45ENSG00000174100.52248.007303040.53180-0.435702.936801.89930HepG2KHSRP
MRPL45ENSG00000174100.51686.169301451.035500.216602.631901.63530HepG2KIF1C
MRPL45ENSG00000174100.51311.026501634.55490-0.318202.397201.34560HepG2LARP7
MRPL45ENSG00000174100.52036.783403206.85440-0.654907.836006.74520HepG2MAGOH
MRPL45ENSG00000174100.52138.945203224.85390-0.592305.952105.05210HepG2MATR3
MRPL45ENSG00000174100.51135.710801675.42330-0.560903.281202.13590HepG2METAP2
MRPL45ENSG00000174100.51250.510601916.92470-0.616309.054507.66840HepG2MSI2
MRPL45ENSG00000174100.51729.846403300.85880-0.9322014.4243013.05290HepG2NCBP2
MRPL45ENSG00000174100.52115.340602672.98920-0.337604.455803.48950HepG2NOL12
MRPL45ENSG00000174100.51146.327401599.08440-0.480202.300201.50470HepG2PABPC1
MRPL45ENSG00000174100.51715.322902939.82100-0.7772010.475609.09060HepG2PABPC4
MRPL45ENSG00000174100.51674.169901925.85140-0.202102.048001.31030HepG2PARN
MRPL45ENSG00000174100.52248.864402995.09120-0.413408.326907.36700HepG2PCBP1
MRPL45ENSG00000174100.51541.010902072.30260-0.427402.366901.40310HepG2PCBP2
MRPL45ENSG00000174100.51459.277201735.36200-0.250002.453401.75450HepG2PPIL4
MRPL45ENSG00000174100.5932.813501257.74050-0.431202.967502.13300HepG2PRPF8
MRPL45ENSG00000174100.51495.654803047.64220-1.0269041.4118039.82050HepG2PTBP1
MRPL45ENSG00000174100.51941.075702551.53400-0.394504.535103.79350HepG2PUF60
MRPL45ENSG00000174100.52188.038302708.48620-0.307806.555605.72430HepG2PUM1
MRPL45ENSG00000174100.52298.743802706.55740-0.235602.340901.72230HepG2PUM2
MRPL45ENSG00000174100.51899.269603300.61860-0.7973021.1285019.63690HepG2QKI
MRPL45ENSG00000174100.51678.386602995.54360-0.8357018.1535016.52500HepG2RBM25
MRPL45ENSG00000174100.51856.942203391.71240-0.8691032.3919030.97330HepG2NELFE
MRPL45ENSG00000174100.52239.556303158.95670-0.4962011.7505010.61340HepG2RECQL
MRPL45ENSG00000174100.5933.558701557.64350-0.7386011.8514010.68370HepG2RPS19
MRPL45ENSG00000174100.51206.644801817.81220-0.591206.493205.29830HepG2RPS2
MRPL45ENSG00000174100.51246.127401756.36910-0.495103.300002.42580HepG2RPS3A
MRPL45ENSG00000174100.51447.580601855.54520-0.358202.606601.56530HepG2RPS5
MRPL45ENSG00000174100.5829.973501244.18230-0.584104.574203.59320HepG2RRP9
MRPL45ENSG00000174100.51143.620101563.37570-0.451103.787402.68540HepG2SERBP1
MRPL45ENSG00000174100.51462.076702189.25120-0.582404.049303.22630HepG2SF3A3
MRPL45ENSG00000174100.51840.312503172.94420-0.7859026.9493025.42830HepG2SF3B4
MRPL45ENSG00000174100.52168.206102446.35950-0.174102.305101.65520HepG2SLBP
MRPL45ENSG00000174100.51502.493102020.59470-0.427409.503008.42480HepG2SMN1
MRPL45ENSG00000174100.52291.333303132.42500-0.4511010.399209.59600HepG2SRFBP1
MRPL45ENSG00000174100.52406.521003311.88500-0.4607011.1860010.37290HepG2SRSF1
MRPL45ENSG00000174100.51132.106101669.34850-0.560304.383203.09740HepG2SRSF3
MRPL45ENSG00000174100.52126.485802519.17250-0.244503.290002.61720HepG2SRSF5
MRPL45ENSG00000174100.51710.965002127.37860-0.314304.427603.57930HepG2SRSF7
MRPL45ENSG00000174100.52115.262002694.41060-0.349106.431305.65250HepG2SRSF9
MRPL45ENSG00000174100.52329.641002719.69950-0.223302.907402.38520HepG2SSB
MRPL45ENSG00000174100.52322.837502865.07510-0.302705.963305.11330HepG2SUCLG1
MRPL45ENSG00000174100.5981.820001622.89280-0.725007.200606.19090HepG2SUPV3L1
MRPL45ENSG00000174100.52342.123702976.90200-0.346005.006604.28890HepG2TAF15
MRPL45ENSG00000174100.51126.443601527.87800-0.439804.014603.16120HepG2TARDBP
MRPL45ENSG00000174100.51885.853102735.31370-0.536508.339606.89200HepG2TIA1
MRPL45ENSG00000174100.51010.056901890.53860-0.9044020.8123019.67650HepG2TIAL1
MRPL45ENSG00000174100.51391.411801907.46280-0.455108.634207.72450HepG2TRIM56
MRPL45ENSG00000174100.51946.731002492.61030-0.356604.009702.93360HepG2TUFM
MRPL45ENSG00000174100.51420.308702026.13320-0.512505.296804.44330HepG2U2AF1
MRPL45ENSG00000174100.52012.467402638.30310-0.390603.088502.20480HepG2UBE2L3
MRPL45ENSG00000174100.5739.85390958.72630-0.373902.303601.60960HepG2UCHL5
MRPL45ENSG00000174100.51168.050001941.53400-0.7331020.8592019.29010HepG2UPF1
MRPL45ENSG00000174100.51445.504701874.47040-0.374905.985005.16070HepG2UTP3
MRPL45ENSG00000174100.51659.756101967.57180-0.245403.375102.64450HepG2ZC3H8
MRPL45ENSG00000174100.51152.237802135.31170-0.8900036.5243035.12490HepG2ZNF622
MRPL45ENSG00000174100.51114.239301941.72180-0.8013012.0026010.90580K562AQR
MRPL45ENSG00000174100.51008.972501279.17830-0.342304.205203.00610K562BCLAF1
MRPL45ENSG00000174100.51120.069501474.77040-0.396902.847301.40550K562BUD13
MRPL45ENSG00000174100.5537.91460773.99030-0.524904.369702.98500K562CCAR1
MRPL45ENSG00000174100.5934.467201219.31660-0.383902.800002.01330K562CPSF6
MRPL45ENSG00000174100.5752.13980970.44740-0.367603.270302.10720K562CSTF2
MRPL45ENSG00000174100.51341.899501633.31460-0.283502.985502.24310K562EIF2S2
MRPL45ENSG00000174100.5518.44120787.30570-0.602703.234802.13970K562EIF3A
MRPL45ENSG00000174100.51163.92560926.681700.328802.386401.62230K562EIF4A3
MRPL45ENSG00000174100.5982.244401245.51930-0.342602.931001.62380K562EXOSC5
MRPL45ENSG00000174100.5896.211901240.53060-0.469004.118803.07150K562FMR1
MRPL45ENSG00000174100.5791.866601051.42030-0.409002.829001.90390K562FTO
MRPL45ENSG00000174100.51268.31290963.703800.396104.611403.85730K562FXR1
MRPL45ENSG00000174100.51090.457401333.07450-0.289802.765701.62620K562GLRX3
MRPL45ENSG00000174100.5916.384901164.18660-0.345302.242601.52690K562GPKOW
MRPL45ENSG00000174100.51790.393602176.61130-0.281802.328001.63220K562GRSF1
MRPL45ENSG00000174100.5435.347501307.78640-1.5869039.9460037.76120K562HNRNPC
MRPL45ENSG00000174100.51679.266301240.890400.436402.931001.65930K562HNRNPK
MRPL45ENSG00000174100.51621.185001251.855500.372902.560701.66850K562HNRNPM
MRPL45ENSG00000174100.52710.243702063.447200.393303.774302.84940K562HSPD1
MRPL45ENSG00000174100.5737.97150993.96710-0.429602.388201.52990K562KRR1
MRPL45ENSG00000174100.5914.496101136.35940-0.313402.217401.43380K562METAP2
MRPL45ENSG00000174100.51079.608001401.54160-0.376505.271504.18090K562MTPAP
MRPL45ENSG00000174100.51227.348301557.30780-0.343505.867704.83870K562NSUN2
MRPL45ENSG00000174100.5989.629201215.26100-0.296302.006101.32270K562POLR2G
MRPL45ENSG00000174100.5825.852601172.56530-0.505705.100403.82270K562PSIP1
MRPL45ENSG00000174100.5756.774901107.03960-0.548804.359803.12140K562SF3B1
MRPL45ENSG00000174100.5707.884301014.14570-0.518704.760103.30850K562SRFBP1
MRPL45ENSG00000174100.5566.82950947.20290-0.740806.867205.21720K562SUPV3L1
MRPL45ENSG00000174100.51483.409001218.871300.283302.483801.70780K562SYNCRIP
MRPL45ENSG00000174100.5725.501101127.81300-0.636506.067204.62700K562TIAL1
MRPL45ENSG00000174100.5927.349901198.14320-0.369603.061802.05630K562TRIM56
MRPL45ENSG00000174100.5748.478301002.43610-0.421502.938301.88230K562UCHL5
MRPL45ENSG00000174100.51415.161501651.24100-0.222602.413401.74050K562UPF1
MRPL45ENSG00000174100.51286.596201689.59420-0.393103.060101.79080K562UTP3
MRPL45ENSG00000174100.51654.881502187.37000-0.402504.131703.04070K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MRPL45 is not available on ENCORE database.





7 RBPs can affect the splicing of MRPL45 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMRPL45ENSG00000174100.5chr17+364624993646259836455316364554343647458536474634-0.051000.000260.00696excludedK562SRSF1
SEMRPL45ENSG00000174100.5chr17+3645871136458833364553163645543436462499364625980.076000.000000.00005includedK562HNRNPC
A3SSMRPL45ENSG00000174100.5chr17+3647798136478182364780083647818236476501364766510.156000.000000.00000longerK562AQR
MXEMRPL45ENSG00000174100.5chr17+3647458536474634364765013647665136462499364625983647800836478182-0.142000.000100.083402includedK562DDX24
MXEMRPL45ENSG00000174100.5chr17+36474585364746343647650136476651364624993646259836478008364781820.101000.000730.067071includedHepG2RBM22
MXEMRPL45ENSG00000174100.5chr17+3647458536474634364765013647665136462499364625983647800836478182-0.157000.000020.001952includedK562FXR1
MXEMRPL45ENSG00000174100.5chr17+3647458536474634364765013647665136462499364625983647800836478182-0.111000.001650.012392includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MRPL45 is not avaliable on ENCORE database.