MC1R

General Information

Gene Name       : MC1R
Gene ID             : ENSG00000258839.3
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MC1R)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MC1RENSG00000258839.30.000.340.17ENCSR000AEF
HepG2MC1RENSG00000258839.38.822.665.74ENCSR985KAT
K562MC1RENSG00000258839.31.921.011.46ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MC1R is not avaliable on ENCORE database.



Proteins bound to RNA
  • MC1R RNA is bound by 15 proteins.  







eCLIP assay for MC1R is not avaliable on ENCORE database.





15 proteins are bound to MC1R RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr168998549489985555+3'-UTR,5'-UTR,intron-Proximal5.397755.29846HepG2DDX3X
chr168998547089985558+3'-UTR,5'-UTR,intron-Proximal5.550328.91871HepG2EIF3H
chr168998094189981029+5'-UTR,intron-Distal7.2234616.62414HepG2DKC1
chr168998075289980817+5'-UTR,intron-Distal5.274149.91231HepG2DKC1
chr168998035489980415+5'-UTR,intron-Distal4.348434.45771K562DHX30
chr168998032289980423+5'-UTR,intron-Distal5.5575010.73999HepG2IGF2BP1
chr168998086289980926+5'-UTR,intron-Distal6.6091412.24808HepG2DKC1
chr168998095489981017+5'-UTR,intron-Distal6.4844613.94931K562EIF4G2
chr168998036389980410+5'-UTR,intron-Distal7.1804511.62592HepG2DKC1
chr168998035689980425+5'-UTR,intron-Distal4.166315.60571HepG2FAM120A
chr168998138889981431+5'-UTR,intron-Distal6.598137.30436HepG2DKC1
chr168998013589980238+5'-UTR,intron-Distal3.130753.56061HepG2STAU2
chr168998057589980632+5'-UTR,intron-Distal5.041597.51195K562TARDBP
chr168997987989979976+5'-UTR,intron-Distal3.486904.50953K562CSTF2T
chr168998139389981440+5'-UTR,intron-Distal4.443303.06243HepG2SRSF7
chr168998138889981441+5'-UTR,intron-Distal3.095583.20331K562CSTF2T
chr168998032689980422+5'-UTR,intron-Distal5.8402752.47812K562EIF4G2
chr168998138789981453+5'-UTR,intron-Distal7.0877320.92297K562EIF4G2
chr168998139089981435+5'-UTR,intron-Distal5.670235.95500K562AATF
chr168998033189980409+5'-UTR,intron-Distal6.8777511.17074K562AATF
chr168998033789980448+5'-UTR,intron-Distal6.2702320.80144K562TARDBP
chr168998097389981006+5'-UTR,intron-Distal3.487434.90204K562TARDBP
chr168998138489981450+5'-UTR,intron-Distal5.2670510.51914K562TARDBP
chr168998004089980100+5'-UTR,intron-Distal3.6588414.00764K562EIF4G2
chr168998077189980925+5'-UTR,intron-Distal5.8713517.20349K562TARDBP
chr168998044689980488+5'-UTR,intron-Distal4.100744.23131HepG2IGF2BP1
chr168998037389980403+5'-UTR,intron-Distal4.610013.06243HepG2SRSF7
chr168998013089980226+5'-UTR,intron-Distal4.6410022.04291K562EIF4G2
chr168998140389981453+5'-UTR,intron-Distal3.270574.09794HepG2IGF2BP1
chr168998044889980543+5'-UTR,intron-Distal5.7984215.10225K562TARDBP
chr168998032889980441+5'-UTR,intron-Distal4.057023.28836HepG2GRSF1
chr168998094789981004+5'-UTR,intron-Distal4.820654.69957HepG2SRSF7
chr168997993189979971+5'-UTR,intron-Distal6.0435012.46423K562EIF4G2
chr168998085789980947+5'-UTR,intron-Distal6.1527420.69973K562EIF4G2
chr168998084889980928+5'-UTR,intron-Distal4.158265.37294K562DHX30
chr168998075689980857+5'-UTR,intron-Distal6.1718120.69973K562EIF4G2
chr168998225989982342+intron-Distal4.078203.76710K562NONO
chr168998229089982339+intron-Distal4.365713.76634HepG2FKBP4
chr168998206689982100+intron-Distal5.410038.94744K562EIF4G2
chr168998240189982447+intron-Distal3.321253.72734HepG2CSTF2T
chr168998227489982331+intron-Distal3.323836.59225HepG2CSTF2T
chr168998204789982122+intron-Distal3.336908.23441HepG2CSTF2T
chr168998157389981601+intron-Distal,intron-Proximal4.183446.26655K562EIF4G2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MC1R is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MC1R is not available on ENCORE database.

  • 117 RBPs can affect the levels of MC1R.  








The Knockdown/knockout RNA-Seq assay for MC1R is not available on ENCORE database.





117 RBPs can affect the gene expression of MC1R :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MC1RENSG00000258839.2401.86730268.100500.583802.797302.26300HepG2AKAP1
MC1RENSG00000258839.2488.58210331.427100.559804.652103.67770HepG2AKAP8L
MC1RENSG00000258839.2390.99340221.819900.817703.438602.56330HepG2ASCC1
MC1RENSG00000258839.2610.22910496.896100.296302.151701.53290HepG2AUH
MC1RENSG00000258839.2308.29320183.550300.748003.221402.21050HepG2BCCIP
MC1RENSG00000258839.2494.31990294.419700.747504.669603.38870HepG2CCAR1
MC1RENSG00000258839.2103.23300210.74770-1.029605.468204.40220HepG2CIRBP
MC1RENSG00000258839.2247.38930151.862600.703903.390702.63780HepG2CPSF6
MC1RENSG00000258839.2427.36580254.011300.750505.635304.09530HepG2CPSF7
MC1RENSG00000258839.2200.08080138.622100.529302.283401.36040HepG2YBX3
MC1RENSG00000258839.2392.64220261.384800.586904.516703.73050HepG2CELF1
MC1RENSG00000258839.2408.01870281.061400.537604.348603.45300HepG2DAZAP1
MC1RENSG00000258839.2109.81050198.69160-0.855504.339003.50950HepG2DDX21
MC1RENSG00000258839.2106.24440194.52940-0.872604.377703.21880HepG2DDX24
MC1RENSG00000258839.2450.37680180.478901.3192010.539109.14760HepG2DDX55
MC1RENSG00000258839.2431.10970220.648100.966207.101606.15070HepG2DDX6
MC1RENSG00000258839.2189.31670315.56660-0.737105.376004.48900HepG2DKC1
MC1RENSG00000258839.2192.16730136.087900.497702.088201.46840HepG2DNAJC21
MC1RENSG00000258839.2274.18850134.927801.022908.058107.01800HepG2DNAJC2
MC1RENSG00000258839.2146.87260220.11120-0.583702.508601.45180HepG2EFTUD2
MC1RENSG00000258839.2362.37070212.060600.772904.813404.04320HepG2EIF2S1
MC1RENSG00000258839.2362.34530228.198800.667003.063302.34250HepG2EIF4B
MC1RENSG00000258839.2179.75420267.21490-0.572002.771801.67710HepG2ESF1
MC1RENSG00000258839.2884.56900570.518500.632608.988508.00870HepG2ETF1
MC1RENSG00000258839.2879.52060311.513301.4973019.4719017.76070HepG2FIP1L1
MC1RENSG00000258839.2416.91860236.503700.817804.207103.36730HepG2FXR1
MC1RENSG00000258839.2720.50880219.350401.7157026.1437024.16900HepG2G3BP1
MC1RENSG00000258839.2803.36810294.381001.448307.551105.72740HepG2GRSF1
MC1RENSG00000258839.2400.07900314.925800.345202.176301.30210HepG2HDGF
MC1RENSG00000258839.2398.18140152.837101.381306.742205.69780HepG2HNRNPC
MC1RENSG00000258839.2316.42260165.634300.933807.742606.62240HepG2HNRNPF
MC1RENSG00000258839.2567.39320222.208901.3523016.5107014.95400HepG2HNRNPK
MC1RENSG00000258839.2109.31560164.27450-0.587601.923501.39030HepG2HNRNPLL
MC1RENSG00000258839.2288.76290151.825600.927407.939306.95240HepG2HNRNPU
MC1RENSG00000258839.2263.41010163.108300.691402.208501.55700HepG2IGF2BP1
MC1RENSG00000258839.2349.33120222.950200.647803.587602.82870HepG2IGF2BP2
MC1RENSG00000258839.2439.74140224.277300.971306.624104.99800HepG2KHSRP
MC1RENSG00000258839.2426.34380301.540000.499604.228602.98110HepG2KIF1C
MC1RENSG00000258839.2406.86180237.897900.774104.701603.89630HepG2MATR3
MC1RENSG00000258839.2452.44970243.491400.893806.169005.23950HepG2NCBP2
MC1RENSG00000258839.2494.19600278.699500.826308.850707.50910HepG2NOL12
MC1RENSG00000258839.2305.28490165.781100.880803.310602.10630HepG2NONO
MC1RENSG00000258839.2433.10370216.797100.998308.323007.08540HepG2PABPC4
MC1RENSG00000258839.2215.61870150.264100.520902.468401.66410HepG2PARN
MC1RENSG00000258839.2263.37530135.413900.959607.646506.46770HepG2PPIL4
MC1RENSG00000258839.2155.14630215.39570-0.473402.242701.53940HepG2PRPF4
MC1RENSG00000258839.289.90100139.16670-0.630402.022501.32800HepG2PRPF8
MC1RENSG00000258839.2384.86740244.980800.651604.726004.05350HepG2PTBP1
MC1RENSG00000258839.2426.43870266.040700.680605.091304.31270HepG2PUF60
MC1RENSG00000258839.2553.35160282.411100.970308.119407.21410HepG2PUM1
MC1RENSG00000258839.2290.53810476.84470-0.714806.900906.16970HepG2RBM22
MC1RENSG00000258839.2350.60160240.823700.541802.993402.29600HepG2RBM25
MC1RENSG00000258839.2530.80260229.131101.211904.295003.04280HepG2RBM27
MC1RENSG00000258839.2441.12550253.908700.796807.365506.43190HepG2RECQL
MC1RENSG00000258839.2319.22960178.342500.839803.538202.78130HepG2RPLP0
MC1RENSG00000258839.2306.42850135.199301.1804012.4066011.18970HepG2SAFB2
MC1RENSG00000258839.2294.61190157.651500.902004.505803.72010HepG2SMN1
MC1RENSG00000258839.2122.52870266.25270-1.119708.070907.36030HepG2SRSF1
MC1RENSG00000258839.2383.83650262.673100.547104.089003.35570HepG2SRSF5
MC1RENSG00000258839.2406.44260162.710301.3206017.7530016.26200HepG2SRSF7
MC1RENSG00000258839.2417.17760216.594800.9456011.0138010.04190HepG2SRSF9
MC1RENSG00000258839.2287.84850467.59890-0.700007.217406.46440HepG2SSB
MC1RENSG00000258839.2773.56430278.461701.473908.860106.79570HepG2STIP1
MC1RENSG00000258839.2418.48140298.734500.486203.615302.92220HepG2SUCLG1
MC1RENSG00000258839.2337.05600219.908200.616003.973302.97840HepG2TIA1
MC1RENSG00000258839.2329.46790147.475101.1596011.1677010.28080HepG2TIAL1
MC1RENSG00000258839.2312.09350148.849101.068008.171307.28360HepG2TRIM56
MC1RENSG00000258839.2379.13560259.905900.544603.285302.32670HepG2TUFM
MC1RENSG00000258839.2419.47810266.449700.654602.677702.05850HepG2U2AF1
MC1RENSG00000258839.2340.31480130.055401.387602.635201.67210HepG2U2AF2
MC1RENSG00000258839.2202.24260106.111500.930404.694703.70070HepG2UCHL5
MC1RENSG00000258839.2405.88680305.152000.411402.647601.61810HepG2UTP18
MC1RENSG00000258839.2286.88090176.843400.697902.934702.18790HepG2XRN2
MC1RENSG00000258839.2439.65310326.511100.429103.390602.80260HepG2ZNF622
MC1RENSG00000258839.2156.6448060.531901.371604.327502.15920K562ADAR
MC1RENSG00000258839.2122.28950271.37280-1.150009.106108.15190K562AGGF1
MC1RENSG00000258839.2136.91650282.37770-1.044307.460306.34350K562AKAP8L
MC1RENSG00000258839.2522.22710200.403701.3817016.5771015.29970K562AQR
MC1RENSG00000258839.2200.56630296.28610-0.562902.757701.84580K562ATP5C1
MC1RENSG00000258839.2172.4885091.279000.918004.512902.77130K562BCCIP
MC1RENSG00000258839.2198.5425088.199501.170507.705306.07530K562BCLAF1
MC1RENSG00000258839.2197.0565059.271901.7331012.9380010.15670K562CCAR1
MC1RENSG00000258839.2193.45110116.302000.734002.373901.40380K562CNOT7
MC1RENSG00000258839.2259.29250146.731900.821302.481201.43630K562CPEB4
MC1RENSG00000258839.2120.8181066.912500.852402.902801.82020K562CSTF2
MC1RENSG00000258839.2158.37450303.84570-0.940007.864006.25240K562DKC1
MC1RENSG00000258839.2133.7017063.738501.068704.455502.71960K562DNAJC21
MC1RENSG00000258839.2181.2445093.356900.957002.965802.02090K562EFTUD2
MC1RENSG00000258839.2180.36830126.476400.512002.043901.40920K562EIF2S2
MC1RENSG00000258839.2196.0381099.881200.972704.062802.77760K562EIF3D
MC1RENSG00000258839.2287.45500113.790201.3369011.526109.81680K562EIF4A3
MC1RENSG00000258839.2300.87440217.341100.469102.253501.40310K562EIF4G2
MC1RENSG00000258839.2183.3975095.428600.942405.012803.25940K562EXOSC5
MC1RENSG00000258839.2220.4609092.070601.259608.703707.10740K562FIP1L1
MC1RENSG00000258839.28.8385028.42850-1.685502.340601.69840K562G3BP2
MC1RENSG00000258839.2217.1725093.604301.214106.664204.47050K562GEMIN5
MC1RENSG00000258839.2137.5974068.706401.001803.924402.98450K562GPKOW
MC1RENSG00000258839.2428.60580168.539801.3465014.0770012.34860K562GRSF1
MC1RENSG00000258839.2228.70580154.711500.563802.762601.69110K562HNRNPA1
MC1RENSG00000258839.2467.5367074.592702.6479017.0214015.62080K562HNRNPC
MC1RENSG00000258839.2130.0850066.583800.966103.704202.36380K562HNRNPF
MC1RENSG00000258839.2493.23680171.331701.5254024.6371022.17170K562HNRNPU
MC1RENSG00000258839.2109.6068059.849800.872802.905301.38580K562KHDRBS1
MC1RENSG00000258839.2405.00900250.366900.693805.297402.68510K562CCAR2
MC1RENSG00000258839.2196.39070299.66610-0.609603.312102.40100K562KIF1C
MC1RENSG00000258839.2136.9735067.887801.012602.159201.41190K562MAGOH
MC1RENSG00000258839.2188.48310286.86010-0.605903.060401.91750K562MAK16
MC1RENSG00000258839.2135.9080067.749601.004204.619803.39860K562MATR3
MC1RENSG00000258839.2139.87830335.70280-1.2630011.507809.43960K562MBNL1
MC1RENSG00000258839.2123.6479067.064800.882503.084402.15790K562METAP2
MC1RENSG00000258839.2353.05170140.284001.3314015.7458014.02250K562MTPAP
MC1RENSG00000258839.2105.45670235.30400-1.157904.611803.38170K562NAA15
MC1RENSG00000258839.2250.36860155.872100.683604.191703.29450K562NSUN2
MC1RENSG00000258839.2148.1979059.416501.318505.524302.66750K562PARN
MC1RENSG00000258839.2106.2456060.402700.814602.537301.60180K562PCBP2
MC1RENSG00000258839.2112.2025066.872500.746502.278701.46580K562PSIP1
MC1RENSG00000258839.2109.77890280.02650-1.3510010.060809.07120K562PUS1
MC1RENSG00000258839.2134.02280272.85580-1.025707.476406.53250K562RBM15
MC1RENSG00000258839.2212.6848063.243601.749609.242907.56330K562RBM22
MC1RENSG00000258839.2116.7922066.554100.811202.837301.73000K562NELFE
MC1RENSG00000258839.2209.68170105.943400.984804.033702.10670K562SBDS
MC1RENSG00000258839.241.66220139.21370-1.740502.663701.49190K562SF1
MC1RENSG00000258839.2249.66720153.800100.698904.187403.19850K562SF3A3
MC1RENSG00000258839.2131.5910065.287401.011104.118202.55640K562SLBP
MC1RENSG00000258839.2225.52430157.571000.517202.432801.54890K562SRPK2
MC1RENSG00000258839.2107.6070061.068100.817202.709601.67370K562SRSF5
MC1RENSG00000258839.2297.21780103.688301.519207.998205.32020K562STIP1
MC1RENSG00000258839.2164.6118087.863100.905603.358302.22840K562SUPV3L1
MC1RENSG00000258839.2519.5949065.440002.989008.704207.35760K562TARDBP
MC1RENSG00000258839.2207.4872063.124501.7166013.6055011.66910K562TIA1
MC1RENSG00000258839.2109.0029064.324600.760802.229001.39730K562TIAL1
MC1RENSG00000258839.2106.1994061.945800.777602.316701.33600K562TRA2A
MC1RENSG00000258839.2122.2848068.295400.840302.959801.97510K562TRIM56
MC1RENSG00000258839.2290.01290165.274100.811206.218405.19240K562UPF1
MC1RENSG00000258839.2220.43970141.420400.640303.207202.26970K562WDR3
MC1RENSG00000258839.2204.89530147.057300.478402.162101.40670K562WDR43
MC1RENSG00000258839.2171.1475094.819800.851902.953801.69150K562XRN2
MC1RENSG00000258839.2351.54850225.767400.638804.197103.09610K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MC1R is not available on ENCORE database.






No RBPs affect the alternative splcing events of MC1R on ENCORE database.





The Knockdown/knockout RNA-Seq assay for MC1R is not avaliable on ENCORE database.