HDDC2

General Information

Gene Name       : HDDC2
Gene ID             : ENSG00000111906.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HDDC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HDDC2ENSG00000111906.1758.5353.1855.86ENCSR000AEF
HepG2HDDC2ENSG00000111906.1757.1365.3761.25ENCSR985KAT
K562HDDC2ENSG00000111906.17205.28197.78201.53ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HDDC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HDDC2 RNA is bound by 23 proteins.  







eCLIP assay for HDDC2 is not avaliable on ENCORE database.





23 proteins are bound to HDDC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6125597116125597184-3'-UTR,intron-Distal3.3236215.18794K562PABPC4
chr6125597082125597187-3'-UTR,intron-Distal4.7679215.80209K562GRWD1
chr6125597097125597182-3'-UTR,intron-Distal3.620643.54552HepG2LARP4
chr6125598353125598386-3'-UTR,5'-UTR,CDS,intron-Distal3.193217.98531K562YBX3
chr6125597350125597396-3'-UTR,CDS,intron-Distal,intron-Proximal4.203688.73115K562BUD13
chr6125597367125597389-3'-UTR,CDS,intron-Distal,intron-Proximal3.5673514.85924K562YBX3
chr6125597129125597233-3'-UTR,intron-Distal6.44181400.00000HepG2SUB1
chr6125598250125598267-3'-UTR,5'-UTR,CDS,intron-Distal3.065136.77593K562YBX3
chr6125597134125597248-3'-UTR,intron-Distal3.9376910.14641K562IGF2BP1
chr6125597067125597096-3'-UTR,intron-Distal4.047504.62617K562PABPC4
chr6125598304125598359-3'-UTR,5'-UTR,CDS,intron-Distal4.239993.79347HepG2GRWD1
chr6125597142125597233-3'-UTR,intron-Distal4.5876921.25906K562NOLC1
chr6125597124125597220-3'-UTR,intron-Distal3.721907.03933K562APOBEC3C
chr6125598247125598250-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.368117.59396K562YBX3
chr6125623019125623129-5'-UTR,CDS,intron-Distal,intron-Proximal3.346288.71990K562DROSHA
chr6125623078125623119-5'-UTR,intron-Distal,intron-Proximal5.521716.02643HepG2DDX3X
chr6125623078125623155-5'-UTR,intron-Distal,intron-Proximal3.708067.50007K562GTF2F1
chr6125613986125614042-5'-UTR,CDS,intron-Distal,intron-Proximal3.058799.69435K562YBX3
chr6125623099125623118-5'-UTR,intron-Distal,intron-Proximal4.641714.46345K562GEMIN5
chr6125623045125623177-5'-UTR,CDS,intron-Distal,intron-Proximal3.268163.59669HepG2PRPF4
chr6125623010125623139-5'-UTR,CDS,intron-Distal,intron-Proximal4.4208714.04029K562DDX6
chr6125622993125623062-CDS,intron-Distal3.8392835.65201K562DDX3X
chr6125622995125623060-CDS,intron-Distal4.9838213.13184HepG2DDX3X
chr6125622953125623000-CDS,intron-Distal4.353013.93614HepG2AQR
chr6125621736125621781-CDS,intron-Distal4.0238622.22883K562DDX3X
chr6125621781125621806-CDS,intron-Distal,intron-Proximal4.4149428.74396K562DDX3X
chr6125623009125623040-CDS,intron-Distal3.925305.70053K562GEMIN5
chr6125602711125602853-intron-Distal3.779513.23532K562MATR3
chr6125618104125618173-intron-Distal3.552063.95937K562UCHL5
chr6125613875125613951-intron-Distal,intron-Proximal3.477587.50310K562KHSRP
chr6125617308125617427-intron-Distal3.444134.76004K562KHSRP
chr6125622973125622995-intron-Distal4.2251010.58560K562AQR
chr6125622951125622973-intron-Distal6.1223711.56697K562AQR
chr6125599922125599975-intron-Distal3.644333.76275K562PTBP1
chr6125614374125614460-intron-Distal,intron-Proximal3.638856.19377K562KHSRP
chr6125605144125605193-intron-Distal3.288733.15041K562EXOSC5
chr6125608806125608913-intron-Distal3.956073.45817K562MATR3
chr6125613109125613265-intron-Distal4.182766.94951K562MATR3
chr6125606593125606722-intron-Distal4.161118.64076K562PTBP1
chr6125622543125622617-intron-Distal3.648255.17677K562EIF4G2
chr6125617959125618066-intron-Distal3.558874.63109K562GRWD1
chr6125614512125614587-intron-Distal4.966619.39339K562KHSRP
chr6125622545125622648-intron-Distal3.894745.27598K562TARDBP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HDDC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HDDC2 is not available on ENCORE database.

  • 88 RBPs can affect the levels of HDDC2.  








The Knockdown/knockout RNA-Seq assay for HDDC2 is not available on ENCORE database.





88 RBPs can affect the gene expression of HDDC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HDDC2ENSG00000111906.13553.28590450.232200.297302.114101.56840HepG2ACO1
HDDC2ENSG00000111906.131006.54530754.661600.415402.421401.92050HepG2AKAP1
HDDC2ENSG00000111906.13290.81070417.31860-0.521103.412402.05370HepG2BUD13
HDDC2ENSG00000111906.13559.45340432.313400.371802.349401.63490HepG2CALR
HDDC2ENSG00000111906.13762.19780593.244900.361402.109701.42880HepG2CIRBP
HDDC2ENSG00000111906.13601.04290336.181700.838105.093304.05090HepG2CNOT7
HDDC2ENSG00000111906.13457.57440355.444100.364302.315501.38510HepG2YBX3
HDDC2ENSG00000111906.13859.74520719.877100.256102.315001.62890HepG2DAZAP1
HDDC2ENSG00000111906.13542.44890416.375800.381503.327902.42210HepG2DDX19B
HDDC2ENSG00000111906.13567.82610398.303700.511503.580702.81710HepG2DDX21
HDDC2ENSG00000111906.13535.60250389.604100.459103.088502.12270HepG2DDX24
HDDC2ENSG00000111906.13414.20180722.92140-0.803507.297206.32560HepG2DDX3X
HDDC2ENSG00000111906.13370.59750526.75620-0.507302.537801.79310HepG2DDX55
HDDC2ENSG00000111906.13446.48340349.039800.355102.179701.54780HepG2DNAJC21
HDDC2ENSG00000111906.13440.21490596.98760-0.439502.475201.91260HepG2EIF2S1
HDDC2ENSG00000111906.13396.51430642.33750-0.696004.203003.36480HepG2EIF4B
HDDC2ENSG00000111906.13641.11100439.910100.543304.701003.61750HepG2EWSR1
HDDC2ENSG00000111906.13553.64050379.481700.544804.052102.70570HepG2FASTKD2
HDDC2ENSG00000111906.13291.98480423.80220-0.537503.463602.58700HepG2FUBP3
HDDC2ENSG00000111906.13299.76670495.44790-0.724904.360002.97560HepG2FUS
HDDC2ENSG00000111906.13451.37820311.208300.536402.482601.42640HepG2GRSF1
HDDC2ENSG00000111906.13486.65130619.25840-0.347702.740402.02600HepG2HNRNPF
HDDC2ENSG00000111906.13450.69020609.79230-0.436203.371802.57930HepG2IGF2BP1
HDDC2ENSG00000111906.13490.97140397.721000.303801.980401.34780HepG2ILF2
HDDC2ENSG00000111906.13175.08070301.48280-0.784103.658101.90730HepG2PNPT1
HDDC2ENSG00000111906.13452.85560664.07790-0.552305.723904.99440HepG2PTBP1
HDDC2ENSG00000111906.131084.77780723.344700.5845011.1133010.09150HepG2PUM1
HDDC2ENSG00000111906.13161.21090452.66280-1.4895010.471109.16570HepG2RAVER1
HDDC2ENSG00000111906.131049.43470792.490100.405004.414703.80020HepG2RBM22
HDDC2ENSG00000111906.13525.69760652.73190-0.312301.892401.32520HepG2RBM25
HDDC2ENSG00000111906.13544.30100739.05500-0.441304.101903.46610HepG2NELFE
HDDC2ENSG00000111906.13509.04540688.32920-0.435304.022503.29770HepG2RECQL
HDDC2ENSG00000111906.13515.19720667.09960-0.372802.335901.69970HepG2RPLP0
HDDC2ENSG00000111906.13664.44310499.927700.410302.343301.35990HepG2RPS5
HDDC2ENSG00000111906.13717.73800556.394100.367301.914801.35130HepG2SF3A3
HDDC2ENSG00000111906.131009.06270721.662400.483506.208105.56950HepG2SRSF1
HDDC2ENSG00000111906.13430.80200608.40240-0.498004.974804.08240HepG2SRSF7
HDDC2ENSG00000111906.13959.55360777.132300.304101.954201.50400HepG2SSB
HDDC2ENSG00000111906.13576.76570400.704300.525303.201101.82830HepG2SSRP1
HDDC2ENSG00000111906.13610.72330405.635200.590203.407201.92320HepG2SUGP2
HDDC2ENSG00000111906.13479.79310381.716600.329802.224401.70770HepG2TRIM56
HDDC2ENSG00000111906.13841.26790481.138400.806008.481207.37810HepG2U2AF1
HDDC2ENSG00000111906.13211.91750309.78110-0.547702.698901.94940HepG2UCHL5
HDDC2ENSG00000111906.13697.84230507.178000.460304.554203.24980HepG2UTP18
HDDC2ENSG00000111906.13795.75430476.393100.7401011.4973010.40870HepG2UTP3
HDDC2ENSG00000111906.133132.029103913.69350-0.321402.846401.60240K562ABCF1
HDDC2ENSG00000111906.134540.218103563.706200.349307.151606.30250K562AGGF1
HDDC2ENSG00000111906.134517.324303708.183400.284702.597601.96350K562AKAP8L
HDDC2ENSG00000111906.132582.432804962.04180-0.9422020.9708019.52830K562AQR
HDDC2ENSG00000111906.132055.315102500.12340-0.282602.248301.38310K562BCLAF1
HDDC2ENSG00000111906.131360.372201892.22770-0.476104.503003.37960K562BOP1
HDDC2ENSG00000111906.131832.772402726.10510-0.572806.061503.90480K562BUD13
HDDC2ENSG00000111906.131008.525401293.44440-0.359002.681701.64890K562CCAR1
HDDC2ENSG00000111906.133165.573603792.34850-0.260603.476702.23220K562CPEB4
HDDC2ENSG00000111906.131532.456702012.02640-0.392804.353903.37120K562CPSF6
HDDC2ENSG00000111906.134573.723803990.361900.196702.189601.42060K562DKC1
HDDC2ENSG00000111906.131497.571102151.00980-0.522405.746704.40180K562EFTUD2
HDDC2ENSG00000111906.132053.175403731.41870-0.8619029.2620027.36940K562EIF2S2
HDDC2ENSG00000111906.131356.412001711.61690-0.335603.870502.46550K562EIF4B
HDDC2ENSG00000111906.131661.227702228.39450-0.423804.687602.99080K562EXOSC5
HDDC2ENSG00000111906.133782.248502813.354500.426904.804803.66490K562FIP1L1
HDDC2ENSG00000111906.131060.853302047.10120-0.9484016.5187014.35670K562FMR1
HDDC2ENSG00000111906.131172.372101735.06480-0.565605.498604.15580K562FTO
HDDC2ENSG00000111906.131323.109801711.57900-0.371404.460102.70710K562FUS
HDDC2ENSG00000111906.132599.698301976.609900.395206.078305.23380K562FXR1
HDDC2ENSG00000111906.132440.735402861.47930-0.229402.391001.33890K562GLRX3
HDDC2ENSG00000111906.131423.976401921.02630-0.432004.474203.47030K562GPKOW
HDDC2ENSG00000111906.131279.997402426.38150-0.9227020.2490018.71620K562HNRNPC
HDDC2ENSG00000111906.131461.043302166.91420-0.568607.782405.79000K562HNRNPF
HDDC2ENSG00000111906.132933.193603546.41180-0.273902.562301.54810K562HNRNPL
HDDC2ENSG00000111906.133495.215802314.055700.594906.509604.99000K562HNRNPM
HDDC2ENSG00000111906.132297.360903703.75020-0.6890017.3132015.19950K562HNRNPU
HDDC2ENSG00000111906.132077.955202604.22880-0.325702.930701.69690K562IGF2BP3
HDDC2ENSG00000111906.131223.891201640.22180-0.422402.648001.73730K562KRR1
HDDC2ENSG00000111906.131345.041201875.12070-0.479305.678004.39510K562METAP2
HDDC2ENSG00000111906.132583.173803008.47260-0.219903.038502.19330K562MTPAP
HDDC2ENSG00000111906.132957.093903342.68170-0.176802.978802.20800K562NSUN2
HDDC2ENSG00000111906.131986.029602394.27610-0.269702.169701.30780K562PCBP2
HDDC2ENSG00000111906.132148.713902834.51620-0.399603.306502.39800K562PCBP3
HDDC2ENSG00000111906.134131.361106032.62840-0.5462010.319707.94450K562PNPT1
HDDC2ENSG00000111906.131745.681102174.24540-0.316703.209302.34240K562POLR2G
HDDC2ENSG00000111906.133931.961903193.759200.299902.516301.73850K562PPIG
HDDC2ENSG00000111906.131484.167002175.54760-0.551707.104205.53530K562PSIP1
HDDC2ENSG00000111906.134503.801406405.63320-0.508207.510906.16420K562PUF60
HDDC2ENSG00000111906.134737.475506675.76580-0.4948012.0936010.08580K562PUM2
HDDC2ENSG00000111906.135316.758003677.604500.531706.897706.08550K562PUS1
HDDC2ENSG00000111906.131120.858202069.67560-0.884807.393504.98490K562RAVER1
HDDC2ENSG00000111906.134465.929503583.185300.317604.499903.76250K562RBM15
HDDC2ENSG00000111906.131582.085502506.96030-0.664109.807008.06990K562RBM22
HDDC2ENSG00000111906.132869.313502140.133700.422902.761201.43600K562RRP9
HDDC2ENSG00000111906.132637.747403298.37610-0.322404.813103.76370K562SF3A3
HDDC2ENSG00000111906.131297.249201826.83200-0.493904.116102.91350K562SF3B1
HDDC2ENSG00000111906.131474.663501881.80970-0.351703.008001.92680K562SRFBP1
HDDC2ENSG00000111906.132151.194202593.90900-0.270001.930401.33260K562TARDBP
HDDC2ENSG00000111906.131359.757502092.48820-0.621906.949905.41170K562TIAL1
HDDC2ENSG00000111906.131634.122802223.22610-0.444104.990803.62990K562TRIM56
HDDC2ENSG00000111906.131569.721802144.90910-0.450404.237902.95040K562UCHL5
HDDC2ENSG00000111906.132605.989703544.31640-0.4437010.648309.35390K562UPF1
HDDC2ENSG00000111906.132166.382802739.03160-0.338402.458601.33260K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HDDC2 is not available on ENCORE database.





16 RBPs can affect the splicing of HDDC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHDDC2ENSG00000111906.13chr6-125619859125619962125613973125614055125621683125621805-0.143000.000000.00028excludedK562PRPF8
SEHDDC2ENSG00000111906.13chr6-1256198591256199621256139731256140551256216831256218050.085000.000490.09039includedK562WDR3
SEHDDC2ENSG00000111906.13chr6-1256198591256199621256139731256140551256216831256218660.096000.000570.00760includedK562AQR
SEHDDC2ENSG00000111906.13chr6-125619859125619962125613973125614075125621683125621866-0.056000.000000.00000excludedK562AQR
SEHDDC2ENSG00000111906.13chr6-125619859125619962125613973125614055125621683125621805-0.162000.000420.04378excludedHepG2SRSF7
SEHDDC2ENSG00000111906.13chr6-1256198591256199621256139861256140551256216831256218050.120000.000000.00073includedK562HNRNPA1
SEHDDC2ENSG00000111906.13chr6-1256198591256199621256139731256140551256216831256218050.110000.000000.00103includedK562NSUN2
SEHDDC2ENSG00000111906.13chr6-125619859125619962125613973125614055125621683125621805-0.141000.000970.06381excludedHepG2HNRNPL
SEHDDC2ENSG00000111906.13chr6-125619859125619962125613973125614055125621683125621805-0.114000.000090.00581excludedK562HNRNPU
SEHDDC2ENSG00000111906.13chr6-125619859125619962125613973125614055125621683125621805-0.085000.000530.01670excludedK562AGGF1
SEHDDC2ENSG00000111906.13chr6-1256198591256199621256139731256140551256216831256218050.092000.000270.03681includedK562CPSF6
SEHDDC2ENSG00000111906.13chr6-125619859125619962125613973125614055125621683125621805-0.123000.000050.00423excludedK562HNRNPK
A3SSHDDC2ENSG00000111906.13chr6-1256139731256141141256139731256140551256216831256218660.093000.000000.00000longerK562AQR
A5SSHDDC2ENSG00000111906.13chr6-125622994125623282125623178125623282125621683125621805-0.077000.000110.02078shorterK562SUPV3L1
A5SSHDDC2ENSG00000111906.13chr6-1256229941256232821256231781256232821256216831256218050.090000.000040.03419longerK562IGF2BP2
A5SSHDDC2ENSG00000111906.13chr6-1256229941256232821256231781256232821256216831256218050.088000.000100.08897longerK562TIA1
A5SSHDDC2ENSG00000111906.13chr6-125622994125623282125623178125623282125621683125621805-0.249000.000000.00000shorterK562TAF15
A5SSHDDC2ENSG00000111906.13chr6-1256229941256232821256231781256232821256216831256218050.178000.000210.04645longerHepG2PTBP1
MXEHDDC2ENSG00000111906.13chr6-125613973125614055125619795125619962125598247125598386125621683125621805-0.097000.001900.053602includedK562PTBP1
MXEHDDC2ENSG00000111906.13chr6-1256139861256140551256198591256199621255982471255983861256216831256218050.071000.006890.046831includedK562AQR
MXEHDDC2ENSG00000111906.13chr6-1256139861256140551256197951256199621255982471255983861256216831256218050.071000.007150.048281includedK562AQR
MXEHDDC2ENSG00000111906.13chr6-125613986125614055125619795125619962125598247125598386125621683125621805-0.110000.000680.029492includedHepG2HNRNPL
MXEHDDC2ENSG00000111906.13chr6-125613986125614055125619795125619962125598247125598386125621683125621805-0.071000.003980.064242includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HDDC2 is not avaliable on ENCORE database.