FECH

General Information

Gene Name       : FECH
Gene ID             : ENSG00000066926.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FECH)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FECHENSG00000066926.1015.2219.7417.48ENCSR000AEF
HepG2FECHENSG00000066926.1016.0216.6316.32ENCSR985KAT
K562FECHENSG00000066926.1057.1349.7353.43ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FECH is not avaliable on ENCORE database.



Proteins bound to RNA
  • FECH RNA is bound by 24 proteins.  







eCLIP assay for FECH is not avaliable on ENCORE database.





24 proteins are bound to FECH RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr185522644555226532-3'-UTR,CDS,intron-Distal,intron-Proximal4.814207.39649K562U2AF2
chr185521714755217208-3'-UTR,intron-Distal3.783807.46319K562IGF2BP1
chr185521588755215952-3'-UTR,intron-Distal4.270944.13050K562LIN28B
chr185521742355217516-3'-UTR,intron-Distal,intron-Proximal5.2377716.64789HepG2SUB1
chr185523019655230213-3'-UTR,CDS,intron-Distal,intron-Proximal4.064823.01429K562IGF2BP1
chr185521756655217618-3'-UTR,intron-Distal3.432435.00403K562IGF2BP1
chr185523011155230183-3'-UTR,CDS,intron-Distal3.909006.50713K562IGF2BP2
chr185523006655230171-3'-UTR,CDS,intron-Distal,intron-Proximal4.552194.02817HepG2PRPF8
chr185521687855216914-3'-UTR,intron-Distal4.5347624.11765K562YBX3
chr185521694455216999-3'-UTR,intron-Distal4.0123112.21651K562PABPC4
chr185523367855233753-3'-UTR,CDS,intron-Distal,intron-Proximal3.447314.97175K562IGF2BP2
chr185522646455226526-3'-UTR,CDS,intron-Distal,intron-Proximal3.157903.80334HepG2U2AF2
chr185524056055240579-3'-UTR,CDS,intron-Distal4.1648112.66213K562YBX3
chr185521778555217832-3'-UTR,intron-Distal3.939766.51752K562PABPC4
chr185521568455215757-3'-UTR,intron-Distal6.6761822.62757K562PUM2
chr185521805555218079-3'-UTR,CDS,intron-Distal3.466755.54400K562YBX3
chr185522162855221662-3'-UTR,CDS,intron-Distal,intron-Proximal3.166683.50696K562BUD13
chr185521681555216915-3'-UTR,intron-Distal3.111507.25305K562KHSRP
chr185521753955217559-3'-UTR,intron-Distal4.794444.18952HepG2SUB1
chr185521739655217478-3'-UTR,intron-Distal,intron-Proximal4.066513.80143K562NOLC1
chr185521694755217009-3'-UTR,intron-Distal4.447215.57376K562CPEB4
chr185521855755218610-3'-UTR,CDS,intron-Distal,intron-Proximal3.498694.44431K562BUD13
chr185521767955217730-3'-UTR,intron-Distal3.533535.39297K562TIA1
chr185522214455222203-3'-UTR,CDS,intron-Distal,intron-Proximal3.457163.26275K562BUD13
chr185522144755221494-3'-UTR,CDS,intron-Distal,intron-Proximal4.027314.98250K562AQR
chr185523367755233715-3'-UTR,CDS,intron-Distal,intron-Proximal4.184143.50232K562IGF2BP1
chr185521682355216860-3'-UTR,intron-Distal4.010017.22820K562YBX3
chr185523010355230190-3'-UTR,CDS,intron-Distal,intron-Proximal3.517393.88509K562SND1
chr185521718555217240-3'-UTR,intron-Distal4.854893.88917K562DDX6
chr185523010755230183-3'-UTR,CDS,intron-Distal3.701415.61746K562LIN28B
chr185521686055216878-3'-UTR,intron-Distal4.0465517.00848K562YBX3
chr185523013255230196-3'-UTR,CDS,intron-Distal5.357308.90208K562IGF2BP1
chr185521803955218077-3'-UTR,CDS,intron-Distal4.037393.39506K562IGF2BP2
chr185523375055233803-3'-UTR,CDS,intron-Distal,intron-Proximal3.212473.81856K562IGF2BP1
chr185521695055216995-3'-UTR,intron-Distal3.328893.26079K562UPF1
chr185522645655226528-3'-UTR,CDS,intron-Distal,intron-Proximal4.150454.20812K562U2AF1
chr185521727855217363-3'-UTR,intron-Distal3.322064.90692K562PUM2
chr185521850155218546-3'-UTR,CDS,intron-Distal,intron-Proximal4.784594.65563K562AQR
chr185525383755253910-5'-UTR,CDS,intron-Distal,intron-Proximal4.353324.31786K562IGF2BP2
chr185524740155247432-5'-UTR,CDS,intron-Distal,intron-Proximal4.109955.63105K562DDX3X
chr185525378355253928-5'-UTR,CDS,intron-Distal,intron-Proximal3.5625211.22044K562DDX3X
chr185524051555240560-CDS,intron-Distal3.324109.30255K562YBX3
chr185524046055240481-CDS,intron-Distal,intron-Proximal3.493614.38107K562AQR
chr185524040555240460-intron-Distal,intron-Proximal4.828327.50107K562AQR
chr185523985255239913-intron-Distal4.1395712.94489K562HNRNPL
chr185524036755240458-intron-Distal,intron-Proximal4.301915.02888K562KHSRP
chr185523980355239907-intron-Distal4.1379224.95464K562AGGF1
chr185523740055237462-intron-Distal4.260756.46071K562HNRNPL
chr185523739555237438-intron-Distal3.511485.10278K562AGGF1
chr185523980755239852-intron-Distal4.9948313.45737K562HNRNPL
chr185523983455239906-intron-Distal4.067423.31153K562GTF2F1
chr185524040655240473-intron-Distal,intron-Proximal3.070215.54603K562PRPF8
chr185523765755237730-intron-Distal3.010384.23584K562HNRNPL
chr185524003855240096-intron-Distal3.893083.76275K562PTBP1
chr185523776255237839-intron-Distal4.057176.46071K562HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FECH is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FECH is not available on ENCORE database.

  • 114 RBPs can affect the levels of FECH.  








The Knockdown/knockout RNA-Seq assay for FECH is not available on ENCORE database.





114 RBPs can affect the gene expression of FECH :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FECHENSG00000066926.6221.43310292.88900-0.403502.205801.65020HepG2ACO1
FECHENSG00000066926.6745.84870444.328300.747205.708204.97600HepG2AKAP1
FECHENSG00000066926.6417.92670649.75190-0.636604.718003.86240HepG2AUH
FECHENSG00000066926.6189.00580372.33530-0.978205.908704.51480HepG2BCCIP
FECHENSG00000066926.6222.47400331.31850-0.574603.059002.43300HepG2BOP1
FECHENSG00000066926.6215.31000304.18020-0.498502.280201.64840HepG2CPSF6
FECHENSG00000066926.6368.97500270.868000.445803.269102.36980HepG2DDX19B
FECHENSG00000066926.6402.48850271.109700.570003.518802.76170HepG2DDX21
FECHENSG00000066926.6250.05500366.06630-0.549902.196001.49980HepG2DDX55
FECHENSG00000066926.6204.08580345.41510-0.759203.180102.13300HepG2DDX59
FECHENSG00000066926.6357.75630246.996900.534402.461101.58990HepG2EEF2
FECHENSG00000066926.6138.98120351.50060-1.3386011.3157010.16480HepG2EIF2S1
FECHENSG00000066926.6345.97890483.94170-0.484102.925702.08980HepG2EIF4G2
FECHENSG00000066926.6269.39810178.516000.593602.905001.98380HepG2GEMIN5
FECHENSG00000066926.679.46940344.84430-2.1175014.6799013.32030HepG2GPKOW
FECHENSG00000066926.6349.95280259.200000.433001.952901.39860HepG2HNRNPA1
FECHENSG00000066926.6306.48700406.43520-0.407202.729002.01590HepG2HNRNPF
FECHENSG00000066926.6254.25820368.07850-0.533702.763102.06650HepG2HNRNPK
FECHENSG00000066926.6300.32530466.44580-0.635206.312905.33450HepG2HNRNPL
FECHENSG00000066926.6158.50080231.85980-0.548802.555601.64060HepG2HNRNPM
FECHENSG00000066926.6419.52970196.949201.090805.529403.80610HepG2HSPD1
FECHENSG00000066926.6312.74060400.22180-0.355801.993301.37130HepG2IGF2BP1
FECHENSG00000066926.6217.28100369.56790-0.766304.822603.95310HepG2IGF2BP2
FECHENSG00000066926.6203.39560292.54440-0.524403.368302.56590HepG2ILF2
FECHENSG00000066926.6653.20820420.816300.634304.066603.05620HepG2LARP4
FECHENSG00000066926.6218.11730338.70190-0.634903.754102.34020HepG2LIN28B
FECHENSG00000066926.6605.01300394.233000.617804.007003.26000HepG2MATR3
FECHENSG00000066926.6486.53000344.085000.499704.328703.59920HepG2PCBP1
FECHENSG00000066926.6263.00870359.95660-0.452702.979202.18070HepG2PRPF4
FECHENSG00000066926.6225.53180350.14020-0.634604.511903.85040HepG2PTBP1
FECHENSG00000066926.6277.44380484.70690-0.804907.189306.28520HepG2PUF60
FECHENSG00000066926.6230.43570514.16370-1.1579014.6370013.17240HepG2PUM2
FECHENSG00000066926.6180.88690298.32250-0.721805.596604.77600HepG2PUS1
FECHENSG00000066926.6254.73030379.16600-0.573903.371502.69120HepG2QKI
FECHENSG00000066926.6468.22550623.47510-0.413102.625402.11780HepG2RBM22
FECHENSG00000066926.6294.98800437.84360-0.569803.703002.93150HepG2RPLP0
FECHENSG00000066926.6293.02040195.102400.586703.128702.48050HepG2RPS19
FECHENSG00000066926.6204.81810358.75470-0.808705.495804.39150HepG2RPS2
FECHENSG00000066926.6266.94890164.302400.700101.992601.31420HepG2RPS3A
FECHENSG00000066926.6289.58060195.802600.564502.582101.67330HepG2SERBP1
FECHENSG00000066926.6365.18780464.76820-0.347902.336101.68260HepG2SLBP
FECHENSG00000066926.6373.70060297.449000.329101.903601.35330HepG2SMN1
FECHENSG00000066926.6596.18080362.448600.717903.559002.66850HepG2SNRNP70
FECHENSG00000066926.6644.83060380.478300.761009.773409.00730HepG2SRSF1
FECHENSG00000066926.6295.44650196.224400.590302.907201.59280HepG2SSRP1
FECHENSG00000066926.6570.96600342.031100.739208.350507.46110HepG2TAF15
FECHENSG00000066926.6339.79180192.737100.817903.062701.94310HepG2TBRG4
FECHENSG00000066926.6127.84240280.77010-1.1350010.944109.93310HepG2TRIM56
FECHENSG00000066926.6160.18570287.47740-0.843705.067104.23090HepG2U2AF1
FECHENSG00000066926.6133.75630332.51090-1.313803.966702.77350HepG2U2AF2
FECHENSG00000066926.6306.41570501.24600-0.710004.208303.16420HepG2UBE2L3
FECHENSG00000066926.6120.39520215.30360-0.838604.088803.16620HepG2UCHL5
FECHENSG00000066926.6270.44020355.23900-0.393502.436901.80050HepG2ZC3H8
FECHENSG00000066926.6486.73770300.215400.697008.110907.30250HepG2ZNF622
FECHENSG00000066926.61507.092202077.82080-0.463305.519603.78370K562AARS
FECHENSG00000066926.62161.339202852.95670-0.400503.152701.61550K562BUD13
FECHENSG00000066926.61641.529601285.599800.352502.334501.38250K562CCAR1
FECHENSG00000066926.63341.114302553.258700.387904.806602.79340K562CEBPZ
FECHENSG00000066926.64532.254403174.894000.513402.869901.78280K562CNOT7
FECHENSG00000066926.62582.746403209.16980-0.313304.951103.44230K562CPEB4
FECHENSG00000066926.62074.973302545.29820-0.294702.850602.05640K562CPSF6
FECHENSG00000066926.68099.631505735.576600.497809.794108.00980K562CELF1
FECHENSG00000066926.63995.144602934.808500.444908.346706.24040K562DDX21
FECHENSG00000066926.61937.814402619.15520-0.434704.295001.71750K562DDX28
FECHENSG00000066926.61506.020301939.00460-0.364603.304302.15520K562DDX3X
FECHENSG00000066926.64252.821303321.012100.356706.978706.00920K562DDX47
FECHENSG00000066926.62021.752801439.178900.490304.666402.85730K562DHX30
FECHENSG00000066926.62383.008403131.59340-0.394106.554705.11950K562DKC1
FECHENSG00000066926.62332.313801465.429700.670303.848301.73880K562DNAJC2
FECHENSG00000066926.64611.653602537.246900.8619010.422808.06370K562EEF2
FECHENSG00000066926.61607.499402451.22010-0.608707.929506.31480K562EFTUD2
FECHENSG00000066926.61233.810703246.28060-1.3957017.3701015.79470K562EIF2S2
FECHENSG00000066926.62317.671701307.696900.825506.485404.89430K562EIF3A
FECHENSG00000066926.62911.617901951.057900.5775011.8192010.15460K562EIF3G
FECHENSG00000066926.61357.737102025.80740-0.577307.435706.09550K562EIF4A3
FECHENSG00000066926.61487.342301824.37460-0.294703.085901.84720K562EIF4B
FECHENSG00000066926.68009.627404664.577600.7799029.7546026.97260K562EIF4G2
FECHENSG00000066926.61578.297702182.46170-0.467603.842301.79420K562FAM120A
FECHENSG00000066926.63915.915202944.161300.411403.003402.11730K562FIP1L1
FECHENSG00000066926.61799.879002589.85400-0.525006.220304.92420K562FMR1
FECHENSG00000066926.61869.269002457.55720-0.394803.400401.79990K562GEMIN5
FECHENSG00000066926.63775.283102303.721200.7125018.7674016.29910K562GLRX3
FECHENSG00000066926.61191.668102430.10300-1.0280022.8459020.40290K562GPKOW
FECHENSG00000066926.63018.361304326.49540-0.519403.214902.40220K562GRSF1
FECHENSG00000066926.64329.004403011.590900.523408.465006.67980K562HNRNPA1
FECHENSG00000066926.61843.236102273.25910-0.302502.801002.20070K562HNRNPC
FECHENSG00000066926.6973.563002421.45410-1.3145017.8770015.08590K562HNRNPM
FECHENSG00000066926.63974.044103334.828500.252902.213001.41550K562HNRNPU
FECHENSG00000066926.62660.313503991.88300-0.585505.657004.53420K562HSPD1
FECHENSG00000066926.61864.901102440.47880-0.388102.755901.73170K562IGF2BP2
FECHENSG00000066926.61902.788702482.50170-0.383703.783302.34570K562IGF2BP3
FECHENSG00000066926.61945.219101343.112300.534305.148703.12480K562ILF3
FECHENSG00000066926.64055.993503088.425200.393102.851302.01180K562KIF1C
FECHENSG00000066926.61577.473702075.08450-0.395602.422801.55570K562KRR1
FECHENSG00000066926.61648.576702201.74480-0.417404.371602.56570K562LARP7
FECHENSG00000066926.61288.287702027.32820-0.654109.610406.72030K562LSM11
FECHENSG00000066926.61585.165502565.35260-0.6945011.8984010.06360K562MAGOH
FECHENSG00000066926.64563.571402560.225100.8338019.7103017.18920K562MATR3
FECHENSG00000066926.61460.216502022.85460-0.470206.307304.48320K562NCBP2
FECHENSG00000066926.64508.346802691.231200.7442015.5982014.02330K562NSUN2
FECHENSG00000066926.63089.955702131.902300.535302.231901.36270K562PABPN1
FECHENSG00000066926.61540.978902282.62080-0.566807.506105.86180K562PCBP2
FECHENSG00000066926.65549.573003376.804300.716609.954408.38200K562PCBP3
FECHENSG00000066926.62206.021803299.76570-0.580905.802003.43110K562PKM
FECHENSG00000066926.64009.979702590.100300.6305012.5871010.93550K562POLR2G
FECHENSG00000066926.61528.396202385.33050-0.642208.567307.24240K562PRPF8
FECHENSG00000066926.61170.114802038.25100-0.8007013.5846011.27250K562PSIP1
FECHENSG00000066926.6909.935002492.36290-1.4537049.1457046.49590K562PTBP1
FECHENSG00000066926.63153.703705089.38910-0.6904012.0239010.31330K562PUF60
FECHENSG00000066926.63397.650405304.01980-0.6425018.3549015.99890K562PUM2
FECHENSG00000066926.61420.263602886.14650-1.0230020.0675018.63420K562PUS1
FECHENSG00000066926.63414.407302812.039600.279903.402202.75570K562RBM15
FECHENSG00000066926.61688.081902390.15450-0.501705.898904.61310K562RBM22
FECHENSG00000066926.61809.726302329.73330-0.364402.983201.52260K562RBM34
FECHENSG00000066926.61222.945901859.81360-0.604809.075707.27640K562RCC2
FECHENSG00000066926.62322.196501921.643100.273004.012702.12220K562RPS10
FECHENSG00000066926.64475.103902831.782600.660104.849002.70520K562RPS3A
FECHENSG00000066926.64494.338402438.557100.8820010.197007.76970K562RRP9
FECHENSG00000066926.63634.122702386.084800.606908.625006.19410K562SDAD1
FECHENSG00000066926.6928.440701949.74080-1.070405.702503.77470K562SF1
FECHENSG00000066926.61541.945202002.24520-0.376904.407503.31730K562SF3B4
FECHENSG00000066926.62030.414701416.047900.519805.681803.85830K562SLBP
FECHENSG00000066926.63457.101302720.465300.345605.080203.85840K562SRPK2
FECHENSG00000066926.62027.497702443.28990-0.269102.460801.78740K562SRSF1
FECHENSG00000066926.63308.734502619.313800.337004.313202.83300K562SRSF7
FECHENSG00000066926.63827.683602948.132100.376605.013402.92200K562SRSF9
FECHENSG00000066926.62475.742902012.554300.298703.868902.31770K562SSB
FECHENSG00000066926.65391.845004440.534100.279903.518201.82040K562SUCLG1
FECHENSG00000066926.61881.334902385.35050-0.342403.703602.73870K562TIA1
FECHENSG00000066926.61696.334902082.90300-0.296202.228101.39270K562TRIM56
FECHENSG00000066926.6707.253801866.45300-1.4000026.0162022.56710K562U2AF1
FECHENSG00000066926.61372.111101927.71970-0.490506.930405.66630K562U2AF2
FECHENSG00000066926.62343.005002853.55940-0.284404.602703.70110K562UPF1
FECHENSG00000066926.63483.200302441.717100.512403.819302.78650K562WDR3
FECHENSG00000066926.64584.426302538.989200.8524042.1312039.61960K562WDR43
FECHENSG00000066926.66162.650005115.646300.268502.639301.38340K562WRN
FECHENSG00000066926.66142.405104863.604900.336703.538602.54030K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FECH is not available on ENCORE database.





8 RBPs can affect the splicing of FECH :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFECHENSG00000066926.6chr18-552185465521860655215514552180785522149155221656-0.064000.000310.00810excludedK562SRSF1
SEFECHENSG00000066926.6chr18-552185465521860655215514552180785522149155221656-0.094000.000000.00011excludedK562SF3B4
SEFECHENSG00000066926.6chr18-552185465521860655215514552180785522149155221656-0.068000.000340.02844excludedK562HNRNPL
SEFECHENSG00000066926.6chr18-552185465521860655215514552180785522149155221656-0.168000.000000.00000excludedK562U2AF2
SEFECHENSG00000066926.6chr18-5525309555253205552473045524743155253785552538440.083000.002500.04071includedK562HNRNPC
A3SSFECHENSG00000066926.6chr18-5523862355238835552386235523877255240477552405970.101000.000030.00420longerHepG2SF3A3
A3SSFECHENSG00000066926.6chr18-5523862355238835552386235523877255240477552405970.069000.003710.07505longerHepG2U2AF2
A3SSFECHENSG00000066926.6chr18-5523862355238835552386235523877255240477552405970.215000.000000.00000longerHepG2U2AF1
A3SSFECHENSG00000066926.6chr18-5523862355238835552386235523877255240477552405970.109000.000000.00033longerK562U2AF1
A5SSFECHENSG00000066926.6chr18-5524728655247431552473045524743155240477552405970.115000.000570.06222longerK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FECH is not avaliable on ENCORE database.