FAM189B

General Information

Gene Name       : FAM189B
Gene ID             : ENSG00000160767.20
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FAM189B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FAM189BENSG00000160767.202.034.363.20ENCSR000AEF
HepG2FAM189BENSG00000160767.2015.756.9611.36ENCSR985KAT
K562FAM189BENSG00000160767.2015.807.9411.87ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FAM189B is not avaliable on ENCORE database.



Proteins bound to RNA
  • FAM189B RNA is bound by 9 proteins.  







eCLIP assay for FAM189B is not avaliable on ENCORE database.





9 proteins are bound to FAM189B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1155217071155217157-3'-UTR,intron-Distal,intron-Proximal4.617076.09204K562YBX3
chr1155217289155217367-3'-UTR,intron-Distal4.528504.31023HepG2LIN28B
chr1155217267155217368-3'-UTR,intron-Distal4.819934.55369K562LIN28B
chr1155218011155218056-3'-UTR,CDS,intron-Distal4.125834.09791K562IGF2BP2
chr1155217390155217480-3'-UTR,intron-Distal3.210063.08972HepG2PCBP2
chr1155218054155218095-3'-UTR,CDS,intron-Distal,intron-Proximal3.330223.61668HepG2IGF2BP1
chr1155225134155225196-5'-UTR,intron-Distal,intron-Proximal5.7355315.44971HepG2DDX3X
chr1155224912155225059-5'-UTR,intron-Distal,intron-Proximal3.246006.40768K562GEMIN5
chr1155224968155225045-5'-UTR,intron-Distal,intron-Proximal3.138223.01032HepG2LARP4
chr1155224884155224983-5'-UTR,intron-Distal,intron-Proximal3.7220810.20469HepG2DDX3X
chr1155225097155225183-5'-UTR,intron-Distal,intron-Proximal3.102703.38111K562DDX3X
chr1155220310155220379-CDS,intron-Distal,intron-Proximal4.384235.01757K562IGF2BP2
chr1155221528155221610-CDS,intron-Distal,intron-Proximal3.867935.47443HepG2PCBP2
chr1155223415155223449-CDS,intron-Distal,intron-Proximal4.310804.00727K562IGF2BP2
chr1155220379155220463-CDS,intron-Distal,intron-Proximal4.319343.87091K562IGF2BP2
chr1155224552155224652-CDS,intron-Distal3.198743.24816K562YBX3
chr1155220070155220174-CDS,intron-Distal4.835707.84681K562IGF2BP2
chr1155221641155221697-CDS,intron-Distal,intron-Proximal3.273206.09506K562IGF2BP2
chr1155220272155220391-CDS,intron-Distal,intron-Proximal5.2820010.10883K562PCBP1
chr1155225196155225243-intron-Distal,intron-Proximal4.116456.96497HepG2DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FAM189B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FAM189B is not available on ENCORE database.

  • 92 RBPs can affect the levels of FAM189B.  








The Knockdown/knockout RNA-Seq assay for FAM189B is not available on ENCORE database.





92 RBPs can affect the gene expression of FAM189B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FAM189BENSG00000160767.16861.389801230.94360-0.515002.345901.47640HepG2ABCF1
FAM189BENSG00000160767.16558.88810354.720000.655805.231603.92560HepG2ADAR
FAM189BENSG00000160767.16482.598001124.24910-1.220102.519002.00930HepG2AKAP1
FAM189BENSG00000160767.161215.854601018.361900.255602.315801.67890HepG2AUH
FAM189BENSG00000160767.16365.76770597.14870-0.707206.767305.63210HepG2CALR
FAM189BENSG00000160767.161481.27800977.930900.598902.606601.66340HepG2CCAR1
FAM189BENSG00000160767.16569.21990944.76800-0.731003.894603.13120HepG2CKAP4
FAM189BENSG00000160767.16124.80960284.35230-1.187903.503802.30650HepG2CSTF2
FAM189BENSG00000160767.16151.35700452.95960-1.581404.846103.97540HepG2DDX21
FAM189BENSG00000160767.16659.89060357.187900.885407.570006.45300HepG2DNAJC21
FAM189BENSG00000160767.16489.65360354.029100.467804.274903.49710HepG2DNAJC2
FAM189BENSG00000160767.16453.84390982.16570-1.113802.352601.76160HepG2EIF4A3
FAM189BENSG00000160767.16320.93030601.86430-0.9072012.6117011.08220HepG2EIF4G1
FAM189BENSG00000160767.161695.38970576.543001.5560038.2374035.68140HepG2EIF4G2
FAM189BENSG00000160767.16649.563701169.31710-0.8481011.6763010.58100HepG2ETF1
FAM189BENSG00000160767.16537.50860923.43530-0.780703.405502.47730HepG2EWSR1
FAM189BENSG00000160767.16413.13570987.36530-1.2570011.443209.89410HepG2FUBP3
FAM189BENSG00000160767.161197.84820712.100900.750203.267502.57700HepG2GPKOW
FAM189BENSG00000160767.16683.50180525.263600.379803.229102.45960HepG2HNRNPF
FAM189BENSG00000160767.161612.62950679.578801.246606.409605.49540HepG2HNRNPLL
FAM189BENSG00000160767.16594.18740398.458400.576402.901702.28210HepG2HNRNPU
FAM189BENSG00000160767.16658.27120517.232700.347802.352201.68280HepG2IGF2BP1
FAM189BENSG00000160767.161635.69380934.646600.807303.748602.97320HepG2IGF2BP2
FAM189BENSG00000160767.16560.74830344.659300.702104.806403.18000HepG2KHDRBS1
FAM189BENSG00000160767.16586.394401005.33350-0.777705.129404.05410HepG2MSI2
FAM189BENSG00000160767.16688.76620335.814001.036308.033305.58740HepG2NOLC1
FAM189BENSG00000160767.16567.31730355.393300.674604.799503.85510HepG2PPIL4
FAM189BENSG00000160767.16184.93420349.07630-0.916502.784901.97390HepG2PRPF8
FAM189BENSG00000160767.16680.627901011.85070-0.572107.943907.11470HepG2PTBP1
FAM189BENSG00000160767.16819.77810577.450900.505404.541303.79900HepG2PUF60
FAM189BENSG00000160767.16620.147401095.74170-0.8212013.3921012.16730HepG2QKI
FAM189BENSG00000160767.16162.79580390.10970-1.260802.631101.94270HepG2RAVER1
FAM189BENSG00000160767.16942.740501366.43110-0.535506.965005.68830HepG2RBM15
FAM189BENSG00000160767.16615.34390977.31160-0.667408.708407.90820HepG2RBM22
FAM189BENSG00000160767.16601.195901126.04680-0.9054018.3127017.15930HepG2NELFE
FAM189BENSG00000160767.16376.91090565.86730-0.586204.407903.57580HepG2RPLP0
FAM189BENSG00000160767.16188.06280345.27460-0.876502.646101.87530HepG2RRP9
FAM189BENSG00000160767.16494.28620354.845700.478102.810802.16270HepG2SAFB2
FAM189BENSG00000160767.161107.045001582.82580-0.515803.548202.78080HepG2SF3A3
FAM189BENSG00000160767.16479.68800672.59910-0.487702.460501.79240HepG2SF3B1
FAM189BENSG00000160767.16670.659801053.36830-0.6514010.295109.26260HepG2SF3B4
FAM189BENSG00000160767.16809.32650553.704400.547507.759206.67300HepG2SLBP
FAM189BENSG00000160767.16815.411101103.80010-0.436904.290303.70610HepG2SRFBP1
FAM189BENSG00000160767.16334.012801099.52880-1.7189055.1808053.66870HepG2SRSF1
FAM189BENSG00000160767.16488.19240723.86020-0.568302.378601.45940HepG2SRSF3
FAM189BENSG00000160767.16889.60470570.159800.641709.782508.70130HepG2SRSF5
FAM189BENSG00000160767.16361.83330894.56000-1.3059033.4177031.91130HepG2SRSF9
FAM189BENSG00000160767.16487.43500316.042000.625003.704902.41500HepG2STIP1
FAM189BENSG00000160767.16527.34980648.41920-0.298202.261701.68900HepG2SUCLG1
FAM189BENSG00000160767.16671.60720988.41140-0.557506.850606.03710HepG2TAF15
FAM189BENSG00000160767.16594.59470908.09650-0.610906.294405.03860HepG2TIA1
FAM189BENSG00000160767.16292.92900387.18260-0.402502.309401.84400HepG2TIAL1
FAM189BENSG00000160767.16829.37920390.637501.0861023.6409022.19060HepG2TRIM56
FAM189BENSG00000160767.16763.49160384.525300.989402.935801.91610HepG2U2AF2
FAM189BENSG00000160767.16901.614101442.78930-0.678307.032205.44410HepG2UTP18
FAM189BENSG00000160767.16428.05350665.97130-0.637708.334907.27420HepG2ZC3H8
FAM189BENSG00000160767.16984.685001543.82620-0.648806.682705.92960HepG2ZNF622
FAM189BENSG00000160767.161517.91580951.786800.673307.097306.25040K562AGGF1
FAM189BENSG00000160767.161331.924501045.974800.348603.123802.06490K562AKAP8
FAM189BENSG00000160767.161643.26830990.403100.730402.390501.78300K562AKAP8L
FAM189BENSG00000160767.16678.68700987.51900-0.541104.464003.75160K562AQR
FAM189BENSG00000160767.161492.732701039.220100.522406.960605.41880K562ATP5C1
FAM189BENSG00000160767.16645.44240448.623000.524703.933202.31450K562BCCIP
FAM189BENSG00000160767.16626.46150433.553800.530905.208103.87520K562BCLAF1
FAM189BENSG00000160767.16407.67100544.07020-0.416402.337601.54160K562BOP1
FAM189BENSG00000160767.161010.41330607.755300.733304.423803.03340K562CCAR1
FAM189BENSG00000160767.161511.795001200.434700.332603.247202.04200K562CPEB4
FAM189BENSG00000160767.161099.549301444.47920-0.393602.201401.33220K562CELF1
FAM189BENSG00000160767.161360.06740691.509000.9758018.9661016.15920K562DDX3X
FAM189BENSG00000160767.16841.525901242.04810-0.561609.347208.23440K562DDX47
FAM189BENSG00000160767.161438.016601065.582600.432303.016802.09570K562DKC1
FAM189BENSG00000160767.16299.85590618.15230-1.043702.835501.81780K562EIF3A
FAM189BENSG00000160767.16952.10400632.357700.590306.723504.70120K562EXOSC5
FAM189BENSG00000160767.16456.85880588.64860-0.365702.080501.33430K562FMR1
FAM189BENSG00000160767.16448.40140751.31470-0.7446010.282809.20080K562FXR1
FAM189BENSG00000160767.16119.97480270.32420-1.172005.756304.65330K562G3BP2
FAM189BENSG00000160767.16703.457701122.50280-0.674207.728205.87440K562HNRNPL
FAM189BENSG00000160767.161499.37840954.606700.6513011.546409.74490K562HNRNPU
FAM189BENSG00000160767.16699.79910914.41300-0.385902.679801.89670K562HSPD1
FAM189BENSG00000160767.16759.03530417.664800.861704.098102.74360K562IGF2BP2
FAM189BENSG00000160767.16225.44560471.64230-1.064908.107306.41300K562KRR1
FAM189BENSG00000160767.16772.27450546.845000.497903.910002.01380K562LSM11
FAM189BENSG00000160767.161389.292401006.114800.465502.540501.52540K562MAK16
FAM189BENSG00000160767.161555.483401177.369700.401702.344601.51800K562MBNL1
FAM189BENSG00000160767.161028.56870664.133700.631002.549901.60970K562PABPN1
FAM189BENSG00000160767.16548.74560804.35280-0.551702.129001.39810K562PCBP3
FAM189BENSG00000160767.16405.32130616.92850-0.606003.656902.72990K562POLR2G
FAM189BENSG00000160767.161276.47480789.534500.693002.759801.33100K562PPP1R8
FAM189BENSG00000160767.16756.922501281.22450-0.759304.584003.53820K562PUF60
FAM189BENSG00000160767.161273.50010982.023400.374902.295701.79110K562PUS1
FAM189BENSG00000160767.161520.00000956.987000.6674012.0106010.77670K562RBM15
FAM189BENSG00000160767.16221.98470424.16240-0.934203.906802.93350K562RPS19
FAM189BENSG00000160767.16797.243701310.48120-0.7170013.5722011.87450K562SF3A3
FAM189BENSG00000160767.16338.10600525.33180-0.635803.806302.65650K562SF3B1
FAM189BENSG00000160767.16694.85250475.454700.547304.376903.00280K562SRFBP1
FAM189BENSG00000160767.16618.27190384.008400.687006.057604.39220K562SRSF4
FAM189BENSG00000160767.16615.08550884.92430-0.524804.402602.64910K562SSRP1
FAM189BENSG00000160767.16140.72420265.33150-0.914902.766901.30590K562TAF15
FAM189BENSG00000160767.16672.19810422.688200.669204.577803.66320K562TARDBP
FAM189BENSG00000160767.16621.05830407.757700.606904.117003.08950K562TIA1
FAM189BENSG00000160767.16925.61550561.714200.720504.470503.20420K562TRIM56
FAM189BENSG00000160767.16184.34550270.39830-0.552702.524701.75750K562U2AF2
FAM189BENSG00000160767.16747.818401025.73390-0.455902.995101.73980K562UTP3
FAM189BENSG00000160767.16759.585101252.96270-0.722109.709008.22890K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FAM189B is not available on ENCORE database.





16 RBPs can affect the splicing of FAM189B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFAM189BENSG00000160767.16chr1-155221292155221392155220885155220955155223415155223523-0.251000.000660.01476excludedK562SRSF1
SEFAM189BENSG00000160767.16chr1-155224190155224247155223415155223523155224443155224755-0.300000.000120.00356excludedK562SF3B4
SEFAM189BENSG00000160767.16chr1-155223649155223769155223415155223523155224443155225178-0.261000.005280.07930excludedHepG2U2AF1
SEFAM189BENSG00000160767.16chr1-1552236491552237691552234151552235231552241901552242750.232000.000250.00863includedHepG2HNRNPK
SEFAM189BENSG00000160767.16chr1-155224190155224326155223415155223523155224443155225178-0.181000.002110.04907excludedHepG2HNRNPK
SEFAM189BENSG00000160767.16chr1-1552236491552237691552234151552235231552244431552251780.220000.000850.06681includedHepG2QKI
SEFAM189BENSG00000160767.16chr1-155223649155223769155223415155223523155224443155225178-0.381000.000000.00012excludedHepG2U2AF2
SEFAM189BENSG00000160767.16chr1-155224190155224247155223415155223523155224443155225274-0.264000.003420.03412excludedK562AQR
SEFAM189BENSG00000160767.16chr1-1552236491552237691552234151552235231552241901552243260.183000.001380.07117includedHepG2NCBP2
SEFAM189BENSG00000160767.16chr1-1552236491552237691552234151552235231552241901552242470.232000.000190.01138includedHepG2MATR3
SEFAM189BENSG00000160767.16chr1-155224190155224326155223415155223523155224443155224699-0.181000.000100.00703excludedHepG2MATR3
SEFAM189BENSG00000160767.16chr1-155224190155224247155223415155223523155224443155224755-0.351000.000010.00042excludedK562U2AF1
SEFAM189BENSG00000160767.16chr1-1552236491552237691552234151552235231552244431552251780.225000.000070.01893includedHepG2RBM15
SEFAM189BENSG00000160767.16chr1-155224190155224247155223415155223523155224443155224755-0.291000.000400.03445excludedK562HNRNPUL1
SEFAM189BENSG00000160767.16chr1-155223649155223769155223415155223523155224443155225178-0.188000.002600.09783excludedHepG2PCBP1
SEFAM189BENSG00000160767.16chr1-155223649155223769155223415155223523155224443155224759-0.175000.000460.07241excludedK562UPF1
SEFAM189BENSG00000160767.16chr1-155224190155224247155223415155223523155224443155224755-0.179000.000510.02399excludedK562SF3B1
SEFAM189BENSG00000160767.16chr1-155224190155224247155223415155223523155224443155224755-0.291000.000100.07649excludedHepG2YBX3
SEFAM189BENSG00000160767.16chr1-155223649155223769155223415155223523155224443155225178-0.270000.000020.00273excludedHepG2SRSF9
SEFAM189BENSG00000160767.16chr1-155220066155220612155218195155218264155220885155220955-0.537000.000000.00000excludedHepG2SRSF9
A3SSFAM189BENSG00000160767.16chr1-1552208851552210221552208851552209551552212921552213920.103000.000060.00057longerK562AQR
A3SSFAM189BENSG00000160767.16chr1-1552200661552207201552200661552206121552208851552209550.061000.000690.00499longerK562AQR
MXEFAM189BENSG00000160767.16chr1-155223649155223769155224190155224326155223415155223523155224443155225178-0.116000.000000.000112includedHepG2RBM15
MXEFAM189BENSG00000160767.16chr1-155223649155223769155224190155224326155223415155223523155224443155225178-0.151000.000030.001612includedHepG2HNRNPK
MXEFAM189BENSG00000160767.16chr1-155223649155223769155224190155224275155223415155223523155224443155225178-0.147000.000100.004082includedHepG2HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FAM189B is not avaliable on ENCORE database.