DRAM1

General Information

Gene Name       : DRAM1
Gene ID             : ENSG00000136048.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DRAM1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DRAM1ENSG00000136048.1336.4322.4129.42ENCSR000AEF
HepG2DRAM1ENSG00000136048.1311.3417.9614.65ENCSR985KAT
K562DRAM1ENSG00000136048.132.092.252.17ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DRAM1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DRAM1 RNA is bound by 7 proteins.  







eCLIP assay for DRAM1 is not avaliable on ENCORE database.





7 proteins are bound to DRAM1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12102315356102315425+3'-UTR,intron-Distal3.771574.59124HepG2FUBP3
chr12102316590102316634+3'-UTR,intron-Distal3.913923.35877HepG2UPF1
chr12102301974102302044+3'-UTR,CDS,intron-Distal3.321883.01092HepG2LIN28B
chr12102316211102316269+3'-UTR,intron-Distal3.060013.05408HepG2UPF1
chr12102315585102315680+3'-UTR,intron-Distal3.871023.06406HepG2IGF2BP1
chr12102316731102316821+3'-UTR,intron-Distal4.553975.35992HepG2UPF1
chr12102315981102316022+3'-UTR,intron-Distal3.841723.35877HepG2UPF1
chr12102271524102271563+5'-UTR6.3511910.46216HepG2DDX3X
chr12102271407102271460+5'-UTR3.6008015.15746HepG2DDX3X
chr12102271460102271515+5'-UTR4.5342621.64325HepG2DDX3X
chr12102271563102271591+5'-UTR,CDS4.766236.83552HepG2DDX3X
chr12102271637102271689+CDS5.7978411.05478HepG2DDX3X
chr12102271591102271637+CDS4.618504.17587HepG2DDX3X
chr12102297648102297737+intron-Distal3.468013.60923HepG2HNRNPL
chr12102280148102280246+intron-Distal3.474753.59771HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DRAM1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DRAM1 is not available on ENCORE database.

  • 104 RBPs can affect the levels of DRAM1.  








The Knockdown/knockout RNA-Seq assay for DRAM1 is not available on ENCORE database.





104 RBPs can affect the gene expression of DRAM1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DRAM1ENSG00000136048.91705.896001114.724300.613707.820206.12790HepG2AATF
DRAM1ENSG00000136048.91793.116401473.938100.282703.461702.61490HepG2AKAP8L
DRAM1ENSG00000136048.93184.402401742.615700.8697013.7358012.10950HepG2ASCC1
DRAM1ENSG00000136048.94318.124901896.962101.1866063.0540060.61590HepG2AUH
DRAM1ENSG00000136048.9711.148701195.11650-0.748906.745205.24300HepG2BCCIP
DRAM1ENSG00000136048.9668.922101038.48970-0.634605.237304.03600HepG2BCLAF1
DRAM1ENSG00000136048.93482.190302055.238800.760605.989904.86250HepG2CNOT7
DRAM1ENSG00000136048.9769.073801288.96960-0.7450013.8562011.71160HepG2YBX3
DRAM1ENSG00000136048.91303.552801799.92340-0.465507.679506.70830HepG2CELF1
DRAM1ENSG00000136048.9822.860301356.79760-0.7215018.2136016.51140HepG2DDX19B
DRAM1ENSG00000136048.9828.074801290.78540-0.6404010.294508.29320HepG2DDX1
DRAM1ENSG00000136048.9989.189901203.54660-0.283002.153801.35880HepG2DDX24
DRAM1ENSG00000136048.9672.379001099.47710-0.709505.187803.48900HepG2DDX27
DRAM1ENSG00000136048.91298.024601974.09670-0.604907.756505.69780HepG2DDX47
DRAM1ENSG00000136048.9691.574701175.03380-0.764707.091905.92330HepG2DDX55
DRAM1ENSG00000136048.92396.048501113.052501.106009.507707.77170HepG2DDX59
DRAM1ENSG00000136048.9750.280901354.93870-0.8527012.0392010.10680HepG2DDX5
DRAM1ENSG00000136048.93023.841501733.001000.803009.866308.77750HepG2DDX6
DRAM1ENSG00000136048.9900.045301220.75460-0.439704.068802.89490HepG2DHX30
DRAM1ENSG00000136048.91094.345801403.54880-0.359004.499803.67290HepG2DKC1
DRAM1ENSG00000136048.9805.170701254.48400-0.6397014.2713012.90540HepG2DNAJC2
DRAM1ENSG00000136048.9750.984101167.41360-0.636506.179704.85360HepG2EEF2
DRAM1ENSG00000136048.9829.494401143.68120-0.463404.980003.43490HepG2EIF2S2
DRAM1ENSG00000136048.9906.262701161.46230-0.357903.202402.04760HepG2EIF3G
DRAM1ENSG00000136048.91223.934201841.20290-0.589105.214204.33830HepG2EIF4A3
DRAM1ENSG00000136048.91278.407102177.91310-0.7686021.8160020.40340HepG2ETF1
DRAM1ENSG00000136048.91074.38610847.000300.343003.024001.79440HepG2FAM120A
DRAM1ENSG00000136048.91338.871301810.66090-0.435503.326201.50500HepG2FMR1
DRAM1ENSG00000136048.9562.05160917.67850-0.707308.326807.00130HepG2FUBP3
DRAM1ENSG00000136048.9454.143301723.24760-1.9239044.7172042.18550HepG2G3BP1
DRAM1ENSG00000136048.9491.174901111.10710-1.1777016.1350014.71180HepG2GPKOW
DRAM1ENSG00000136048.9838.624701197.40770-0.513803.673901.49890HepG2GRWD1
DRAM1ENSG00000136048.91726.312401400.602900.301503.963102.80780HepG2HDGF
DRAM1ENSG00000136048.9793.388101277.82140-0.687608.843107.78370HepG2HNRNPA1
DRAM1ENSG00000136048.91094.409601421.32820-0.377103.189802.45210HepG2HNRNPC
DRAM1ENSG00000136048.9745.931501060.34910-0.507404.140703.38570HepG2HNRNPLL
DRAM1ENSG00000136048.9883.328701442.24400-0.7073019.7469017.99760HepG2ILF2
DRAM1ENSG00000136048.91389.323402003.54350-0.528203.435301.93760HepG2ILF3
DRAM1ENSG00000136048.91071.484601761.83860-0.717506.262704.69540HepG2KHSRP
DRAM1ENSG00000136048.91671.477701341.059400.317705.000303.63620HepG2KIF1C
DRAM1ENSG00000136048.93065.852101766.034000.795707.773005.70670HepG2KRR1
DRAM1ENSG00000136048.91363.879702032.06530-0.575203.759802.78950HepG2LARP4
DRAM1ENSG00000136048.9996.669901263.66810-0.342402.516801.43800HepG2LARP7
DRAM1ENSG00000136048.9824.150901326.99190-0.687208.202306.20370HepG2LIN28B
DRAM1ENSG00000136048.9371.285301858.24910-2.3233065.7098062.72920HepG2MAGOH
DRAM1ENSG00000136048.91518.017901232.054100.301002.279301.54230HepG2MSI2
DRAM1ENSG00000136048.91104.192901912.69520-0.792609.566008.42910HepG2NCBP2
DRAM1ENSG00000136048.9840.806601142.63510-0.442503.647102.01470HepG2NIP7
DRAM1ENSG00000136048.92265.211901919.204900.239002.176401.49840HepG2NOL12
DRAM1ENSG00000136048.9693.194701078.91600-0.638303.144001.97450HepG2NONO
DRAM1ENSG00000136048.91021.639701878.33590-0.878606.489805.09230HepG2PABPC1
DRAM1ENSG00000136048.9678.861001703.43790-1.3273024.4454022.35440HepG2PABPC4
DRAM1ENSG00000136048.9968.429401723.50280-0.8316022.8170021.35360HepG2PCBP1
DRAM1ENSG00000136048.9604.48330783.70150-0.374603.037601.74690HepG2PKM
DRAM1ENSG00000136048.91268.005001842.98760-0.539503.023601.43410HepG2PNPT1
DRAM1ENSG00000136048.9906.558701716.49320-0.9210011.111707.51210HepG2PPIG
DRAM1ENSG00000136048.9861.586901259.33270-0.547608.155506.93820HepG2PPIL4
DRAM1ENSG00000136048.91666.46770914.497700.8656023.2647021.41580HepG2PRPF4
DRAM1ENSG00000136048.9981.323201753.71180-0.8376022.2423020.97470HepG2PTBP1
DRAM1ENSG00000136048.91228.397301944.73060-0.6628020.8626019.53980HepG2PUM1
DRAM1ENSG00000136048.9786.244501494.25980-0.9264027.9553026.37500HepG2PUS1
DRAM1ENSG00000136048.9543.222101429.12650-1.3955013.6126012.16050HepG2RAVER1
DRAM1ENSG00000136048.92126.518801682.244300.338003.646402.67670HepG2RBM15
DRAM1ENSG00000136048.9669.045801723.76770-1.3654036.4130034.19870HepG2RBM25
DRAM1ENSG00000136048.9918.022101237.35830-0.430702.289301.32640HepG2RCC2
DRAM1ENSG00000136048.91505.819801817.74300-0.271603.275702.61220HepG2RECQL
DRAM1ENSG00000136048.91893.823001287.571100.556506.397505.42010HepG2RPLP0
DRAM1ENSG00000136048.92468.730801403.985600.814107.033205.57980HepG2RPS10
DRAM1ENSG00000136048.9685.90200922.13770-0.427003.546802.85960HepG2RPS19
DRAM1ENSG00000136048.91199.912702063.30320-0.782007.445306.14850HepG2RPS3A
DRAM1ENSG00000136048.91053.106401434.51490-0.445903.635602.39740HepG2RPS5
DRAM1ENSG00000136048.91093.708601555.00700-0.507702.912201.35010HepG2RTF1
DRAM1ENSG00000136048.91155.231901942.97220-0.750107.453805.36970HepG2SART3
DRAM1ENSG00000136048.9498.53120925.48880-0.8925010.744708.94570HepG2SERBP1
DRAM1ENSG00000136048.92074.922201556.851200.414302.484501.84610HepG2SF3A3
DRAM1ENSG00000136048.91135.208001825.87030-0.6856016.2034014.95370HepG2SF3B4
DRAM1ENSG00000136048.91106.784001756.54340-0.6664018.2387016.73340HepG2SLBP
DRAM1ENSG00000136048.91072.985001466.34670-0.450608.890607.84220HepG2SMN1
DRAM1ENSG00000136048.91806.766401167.797100.629504.301203.31840HepG2SNRNP70
DRAM1ENSG00000136048.93333.052002056.030500.6969025.0202023.90660HepG2SRFBP1
DRAM1ENSG00000136048.91240.147001905.80110-0.6199014.3183013.42200HepG2SRSF1
DRAM1ENSG00000136048.92475.376201808.806200.452508.824007.78850HepG2SRSF5
DRAM1ENSG00000136048.91430.837001174.227800.285003.028402.30550HepG2SRSF7
DRAM1ENSG00000136048.92584.823001550.460200.7373011.2962010.31410HepG2SRSF9
DRAM1ENSG00000136048.92545.772301760.730800.531804.811403.17180HepG2SSRP1
DRAM1ENSG00000136048.9846.247401169.75060-0.467003.075302.36660HepG2SUPV3L1
DRAM1ENSG00000136048.9747.713701712.97440-1.1959036.7414034.99950HepG2TAF15
DRAM1ENSG00000136048.9548.76760784.05650-0.514803.524702.41520HepG2TFIP11
DRAM1ENSG00000136048.9650.085701384.21730-1.0904033.2611031.57250HepG2TRIM56
DRAM1ENSG00000136048.9518.398501302.30910-1.3289024.9603023.01670HepG2U2AF1
DRAM1ENSG00000136048.91407.773901894.37540-0.428303.335902.41740HepG2UBE2L3
DRAM1ENSG00000136048.93631.626701380.691501.3951089.1301086.46070HepG2UPF1
DRAM1ENSG00000136048.91724.987401419.139400.281502.593801.57330HepG2UTP18
DRAM1ENSG00000136048.91125.321001332.99960-0.244302.326401.76650HepG2UTP3
DRAM1ENSG00000136048.91212.090101848.07970-0.608504.649203.21390HepG2XPO5
DRAM1ENSG00000136048.91267.176901518.49280-0.261003.457202.86500HepG2ZNF622
DRAM1ENSG00000136048.995.94780149.00630-0.635102.251801.73140K562AGGF1
DRAM1ENSG00000136048.988.57890155.04760-0.807703.239202.53100K562AKAP8L
DRAM1ENSG00000136048.9252.83060142.420700.827904.218802.63220K562APOBEC3C
DRAM1ENSG00000136048.9169.2799099.293900.769502.526801.52060K562CNOT7
DRAM1ENSG00000136048.9246.57580122.318101.011307.812306.79310K562DDX47
DRAM1ENSG00000136048.9164.8004081.292701.019404.437503.09060K562EIF3D
DRAM1ENSG00000136048.9279.42430142.803600.968302.793601.99480K562HSPD1
DRAM1ENSG00000136048.976.22900129.20310-0.761202.079001.33650K562NAA15
DRAM1ENSG00000136048.9133.8735073.882500.857502.812902.05730K562PRPF8
DRAM1ENSG00000136048.9281.97200176.104900.679003.695302.75450K562PUF60
DRAM1ENSG00000136048.9331.31650187.314600.822605.871604.26400K562PUM1
DRAM1ENSG00000136048.936.93300153.76560-2.0577011.0826010.04580K562PUS1
DRAM1ENSG00000136048.982.28530149.82070-0.864503.582902.92190K562RBM15
DRAM1ENSG00000136048.9186.3733075.258701.308205.266504.13690K562RPS19
DRAM1ENSG00000136048.9112.8018051.572601.129004.059602.91020K562TIAL1
DRAM1ENSG00000136048.9171.29900107.211600.676003.047202.29420K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DRAM1 is not available on ENCORE database.





8 RBPs can affect the splicing of DRAM1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDRAM1ENSG00000136048.9chr12+102313886102313979102307951102308010102314993102315320-0.065000.006860.09679excludedHepG2U2AF1
SEDRAM1ENSG00000136048.9chr12+1023079511023080101022950681022952111023138861023139790.401000.000040.00084includedHepG2U2AF2
SEDRAM1ENSG00000136048.9chr12+102313886102313979102307951102308010102314993102315320-0.127000.000000.00001excludedHepG2U2AF2
SEDRAM1ENSG00000136048.9chr12+1023079511023080101022950681022952111023138861023139790.555000.000000.00001includedHepG2SFPQ
SEDRAM1ENSG00000136048.9chr12+1023079511023080101022950681022952111023138861023139790.379000.000100.02351includedHepG2HNRNPUL1
SEDRAM1ENSG00000136048.9chr12+1023079511023080101022950681022952111023138861023139790.170000.000670.07181includedHepG2SSB
SEDRAM1ENSG00000136048.9chr12+102313886102313979102307951102308010102314993102315320-0.127000.000040.00322excludedHepG2HNRNPU
SEDRAM1ENSG00000136048.9chr12+1022838771022839991022714681022716981022916401022917080.355000.000000.00000includedHepG2HNRNPC
MXEDRAM1ENSG00000136048.9chr12+1023079511023080101023138861023139791022950681022952111023149931023174010.122000.001320.046391includedHepG2TAF15
MXEDRAM1ENSG00000136048.9chr12+1023079511023080101023138861023139791022950681022952111023149931023174010.094000.000000.000001includedHepG2U2AF2
MXEDRAM1ENSG00000136048.9chr12+1023079511023080101023138861023139791022950681022952111023149931023153200.098000.000350.013731includedHepG2HNRNPU

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DRAM1 is not avaliable on ENCORE database.