TOP1

General Information

Gene Name       : TOP1
Gene ID             : ENSG00000198900.5
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TOP1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TOP1ENSG00000198900.5100.3587.3593.85ENCSR000AEF
HepG2TOP1ENSG00000198900.553.7592.9973.37ENCSR985KAT
K562TOP1ENSG00000198900.573.3285.7379.53ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TOP1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TOP1 RNA is bound by 46 proteins.  







eCLIP assay for TOP1 is not avaliable on ENCORE database.





46 proteins are bound to TOP1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr203975262639752691+3'-UTR3.346504.27848HepG2TIA1
chr203975193039751982+3'-UTR,CDS4.3412213.93122HepG2BCLAF1
chr203975263439752713+3'-UTR3.8300519.68795K562TIA1
chr203975197639752026+3'-UTR3.498744.73347HepG2SUB1
chr203975195139751976+3'-UTR5.159809.54529K562GRWD1
chr203975194339751976+3'-UTR4.576215.07810HepG2ZNF800
chr203975246139752527+3'-UTR4.189714.43679K562IGF2BP1
chr203975281939752875+3'-UTR4.555975.54754K562IGF2BP1
chr203975271339752763+3'-UTR3.571307.46662K562TIA1
chr203975279039752865+3'-UTR3.6208715.59596K562PUM2
chr203975194339751984+3'-UTR4.0898812.15981K562LIN28B
chr203975193739751975+3'-UTR3.2820114.01110K562UCHL5
chr203975191739751964+3'-UTR,CDS3.6314912.26691K562ZNF622
chr203975262339752696+3'-UTR4.442233.88726HepG2TIAL1
chr203975194939751973+3'-UTR3.719195.73981HepG2GRWD1
chr203975192739751943+3'-UTR,CDS4.6807616.50038K562LIN28B
chr203975193039751951+3'-UTR,CDS4.268278.89788K562GRWD1
chr203965758139657644+5'-UTR3.4015112.32403K562YBX3
chr203965749539657582+5'-UTR3.175818.58813K562FMR1
chr203972879639728841+CDS3.881083.76642HepG2UCHL5
chr203972984839729878+CDS,intron-Proximal4.1175723.60739K562ZNF622
chr203974149439741530+CDS3.9215013.09306K562ZNF622
chr203974403839744073+CDS4.870315.01842HepG2PRPF8
chr203975187439751918+CDS4.1173619.39526K562UCHL5
chr203972585939725904+CDS,intron-Proximal4.2081812.05445HepG2GRWD1
chr203972121839721227+CDS3.3511114.72846K562UCHL5
chr203974265039742697+CDS3.9704018.48710K562ZNF622
chr203975189339751927+CDS3.417463.91115K562LIN28B
chr203971319839713208+CDS5.133628.91890K562TRA2A
chr203972115439721218+CDS5.2566031.33478HepG2BCLAF1
chr203972110839721165+CDS,intron-Proximal3.0635812.87005HepG2BUD13
chr203971319439713207+CDS3.351384.33822HepG2FXR2
chr203970979939709882+CDS,intron-Proximal3.1102110.80610K562GPKOW
chr203972885339728884+CDS,intron-Proximal3.680447.74559HepG2ZNF800
chr203972984839729893+CDS,intron-Proximal3.131104.34339HepG2FXR2
chr203975183639751851+CDS3.5349410.32712K562ZNF622
chr203972115739721214+CDS3.426735.90242K562CPSF6
chr203969010939690133+CDS,intron-Proximal3.376007.38298HepG2AQR
chr203972121839721272+CDS,intron-Proximal4.285538.23899K562PRPF8
chr203972984839729857+CDS,intron-Proximal3.235965.93304HepG2ZNF800
chr203971313839713159+CDS3.9673413.10875HepG2BCLAF1
chr203972989339729951+CDS4.122343.15232HepG2LIN28B
chr203965805739658187+CDS,intron-Proximal3.601773.76829K562U2AF1
chr203971319639713208+CDS3.8396217.42788K562UCHL5
chr203972112139721150+CDS4.2168221.96758K562ZNF622
chr203972112139721158+CDS3.206445.11645HepG2GRWD1
chr203972872139728789+CDS3.3904219.82356K562PUM1
chr203972121539721227+CDS3.135834.64208HepG2GRWD1
chr203971319539713208+CDS3.3530920.12724K562PUM1
chr203972987839729896+CDS3.7781013.63918K562ZNF622
chr203974271939742746+CDS5.1383215.74878K562ZNF622
chr203971310139713128+CDS,intron-Proximal4.708033.22248HepG2TRA2A
chr203970622439706245+CDS5.6167124.00850K562UCHL5
chr203971316139713203+CDS3.421284.83522HepG2ZNF800
chr203972882739728845+CDS4.8839814.45337HepG2GRWD1
chr203971319539713209+CDS,intron-Proximal3.415615.07370K562CPSF6
chr203972682039726880+CDS,intron-Proximal3.490849.99495HepG2U2AF2
chr203975188639751919+CDS3.838607.44851HepG2GRWD1
chr203972585939725864+CDS,intron-Proximal3.224967.30210K562ZNF622
chr203972586639725884+CDS3.162395.94265K562GRWD1
chr203972884539728861+CDS5.036977.17283HepG2GRWD1
chr203972875239728792+CDS3.691459.58775HepG2GRWD1
chr203972984839729852+CDS,intron-Proximal4.093086.84754HepG2GRWD1
chr203974143839741510+CDS4.902736.31252K562FMR1
chr203974273339742761+CDS4.751207.77351K562GRWD1
chr203972685639726872+CDS3.037414.64055K562GRWD1
chr203970624539706276+CDS5.9681130.74869K562UCHL5
chr203972121139721225+CDS3.159759.60241K562BUD13
chr203972116639721210+CDS3.1161914.48943K562AGGF1
chr203972886039728883+CDS4.5026721.21700K562ZNF622
chr203972116939721215+CDS3.876519.03588K562GRWD1
chr203972115039721214+CDS3.7192131.78497K562ZNF622
chr203975185739751921+CDS3.6080510.53529K562GRWD1
chr203975078639750794+CDS3.181014.29277HepG2GRWD1
chr203972984939729895+CDS4.0099215.82151HepG2BCLAF1
chr203972113939721151+CDS3.227086.56666K562YBX3
chr203970983539709864+CDS4.200078.79898HepG2BCLAF1
chr203972111039721155+CDS,intron-Proximal4.4555510.17130K562TRA2A
chr203972586039725887+CDS3.042654.86633K562RBM15
chr203965772839657748+CDS,intron-Proximal3.5410314.68407HepG2PRPF8
chr203972112739721157+CDS3.3599918.88874K562PUM1
chr203972876539728853+CDS4.1951133.70174K562ZNF622
chr203972873239728763+CDS5.0445913.34504K562ZNF622
chr203972585839725890+CDS,intron-Proximal3.1540810.38337K562BUD13
chr203972116639721222+CDS4.143166.90563HepG2FXR2
chr203971310039713135+CDS,intron-Proximal5.278267.52509K562CPSF6
chr203972597139725979+CDS4.2721311.98560K562UCHL5
chr203970487639704924+CDS3.104863.97169HepG2FXR2
chr203975183439751849+CDS,intron-Proximal3.505106.17947K562PUM1
chr203975183739751848+CDS3.6483110.62851K562UCHL5
chr203970981939709881+CDS,intron-Proximal3.572439.48085K562CPSF6
chr203972111139721121+CDS,intron-Proximal3.600667.39995HepG2BCLAF1
chr203972887639728924+CDS,intron-Proximal4.138426.04280HepG2PRPF8
chr203965773939657747+CDS,intron-Proximal5.564728.16909HepG2AQR
chr203971313739713198+CDS5.6904314.58803K562TRA2A
chr203972877939728848+CDS3.110847.65604HepG2FXR2
chr203972111139721153+CDS,intron-Proximal4.000523.87318HepG2TRA2A
chr203972111339721225+CDS4.9035720.17562HepG2ZNF800
chr203971316539713189+CDS3.3879725.56888K562PUM1
chr203971313539713195+CDS4.9455311.35934K562CPSF6
chr203972985539729900+CDS3.884413.02618HepG2UCHL5
chr203972984839729896+CDS,intron-Proximal3.089098.51428K562BUD13
chr203972111139721121+CDS,intron-Proximal3.6909211.97898K562ZNF622
chr203972694739726969+CDS3.8160114.72633HepG2BCLAF1
chr203970872439708765+CDS,intron-Proximal3.2848412.60600K562BUD13
chr203975076439750794+CDS3.109966.23020K562PUM1
chr203974274039742758+CDS5.5490810.47286HepG2BCLAF1
chr203972984839729896+CDS,intron-Proximal3.2636712.85183K562PUM1
chr203975183639751857+CDS3.601567.91838K562GRWD1
chr203972882539728861+CDS4.8337828.23946K562UCHL5
chr203970873539708754+CDS4.9597118.82504K562UCHL5
chr203965807039658160+CDS,intron-Proximal3.3906210.31829HepG2BUD13
chr203972110339721151+CDS,intron-Proximal4.148824.41713HepG2SRSF1
chr203974493039744960+CDS3.625566.81726HepG2GRWD1
chr203972689739726947+CDS3.6423222.53290HepG2BCLAF1
chr203972121839721227+CDS4.6822715.51821HepG2BCLAF1
chr203975186739751886+CDS3.489495.54854HepG2GRWD1
chr203972886339728883+CDS4.2891912.54435K562PUM1
chr203970622339706275+CDS3.789489.99008HepG2FXR2
chr203972984839729936+CDS,intron-Proximal4.5940144.23423K562UCHL5
chr203972115039721169+CDS4.141888.89788K562GRWD1
chr203972876739728825+CDS4.4697937.31811K562UCHL5
chr203972984839729855+CDS,intron-Proximal3.733974.56136K562GRWD1
chr203972882239728858+CDS3.3765521.37945K562ZNF800
chr203970622139706249+CDS,intron-Proximal3.664408.09841HepG2BUD13
chr203974148639741564+CDS3.167209.18072HepG2GRWD1
chr203970872539708744+CDS3.724604.83483HepG2FXR2
chr203975059039750651+CDS,intron-Proximal3.798783.01266HepG2SF3B4
chr203972116539721215+CDS3.172166.24144HepG2GRWD1
chr203972886139728883+CDS4.451058.16229HepG2GRWD1
chr203971310239713119+CDS4.304144.02380K562TRA2A
chr203970982439709886+CDS,intron-Proximal4.959697.25670HepG2TRA2A
chr203972596839726013+CDS,intron-Proximal4.393064.19412K562EFTUD2
chr203972984939729872+CDS3.260069.19186K562ZNF800
chr203972580339725879+CDS,intron-Proximal3.6552812.96871K562SF3B4
chr203972885839728878+CDS4.8629816.00410K562ZNF800
chr203970872439708735+CDS,intron-Proximal4.7986818.46112K562UCHL5
chr203975185539751916+CDS3.6534420.53066K562ZNF622
chr203971314039713196+CDS4.4931627.95241K562UCHL5
chr203974151539741552+CDS3.9288418.27527K562UCHL5
chr203972886739728880+CDS3.453969.84433HepG2BCLAF1
chr203972988939729958+CDS4.045447.70026K562LIN28B
chr203975187239751912+CDS3.9118214.30125HepG2BCLAF1
chr203971316439713194+CDS4.624637.30246HepG2FXR2
chr203974260139742645+CDS,intron-Proximal3.542349.76884HepG2BUD13
chr203974145639741475+CDS3.106393.50899K562TRA2A
chr203972596939725985+CDS,intron-Proximal3.308187.33138HepG2BCLAF1
chr203972685539726891+CDS4.1072718.56668K562UCHL5
chr203972112139721154+CDS4.6066217.55697HepG2BCLAF1
chr203972586039725866+CDS4.414084.83285K562GRWD1
chr203972586039725907+CDS3.080895.79202HepG2U2AF2
chr203972111039721166+CDS,intron-Proximal3.119338.67187HepG2FXR2
chr203971315939713184+CDS4.4705514.60232HepG2BCLAF1
chr203972689139726963+CDS4.7571329.85421K562UCHL5
chr203972879239728827+CDS4.3100319.00342HepG2GRWD1
chr203974260939742688+CDS,intron-Proximal3.218509.08072K562GRWD1
chr203972879239728841+CDS4.0846218.28673HepG2BCLAF1
chr203972872739728767+CDS4.1588219.72986K562UCHL5
chr203971313839713212+CDS,intron-Proximal6.2192211.32317HepG2TRA2A
chr203974407339744125+CDS,intron-Proximal4.925508.11807HepG2PRPF8
chr203971315539713189+CDS3.8395115.90392K562ZNF622
chr203972111139721119+CDS,intron-Proximal3.5324019.30349K562PUM1
chr203972998739730030+CDS,intron-Proximal5.0552711.09609HepG2PRPF8
chr203971313639713207+CDS3.600044.78288K562SRSF7
chr203970983139709880+CDS5.2510810.04362K562TRA2A
chr203970872439708737+CDS,intron-Proximal3.342997.10301K562ZNF800
chr203975076839750785+CDS3.417205.96568HepG2GRWD1
chr203974273039742765+CDS4.6180513.11867HepG2GRWD1
chr203971312939713165+CDS3.1398720.99879K562PUM1
chr203970872239708747+CDS,intron-Proximal5.132737.90091HepG2AQR
chr203972886139728883+CDS4.6635624.44202K562UCHL5
chr203975188339751909+CDS3.316915.93018K562PUM1
chr203972887039728883+CDS4.687575.77211K562GRWD1
chr203975077039750792+CDS3.8072510.58978K562ZNF622
chr203974148439741515+CDS3.9691217.09641K562UCHL5
chr203970622339706266+CDS3.094757.82446HepG2AQR
chr203965807339658145+CDS,intron-Proximal3.2274414.65525HepG2PRPF8
chr203972690639726960+CDS4.3229212.05445HepG2GRWD1
chr203975074339750781+CDS4.416625.82137K562YBX3
chr203972596939726015+CDS,intron-Proximal4.389947.13970HepG2PRPF8
chr203972985539729897+CDS3.6708711.46122K562GRWD1
chr203972586139725898+CDS3.149634.67625HepG2ZNF800
chr203972116139721218+CDS4.7856436.75567K562UCHL5
chr203972985239729877+CDS3.672518.83482HepG2GRWD1
chr203974143639741481+CDS3.797114.49000K562FXR2
chr203971319939713208+CDS3.3179711.06731K562ZNF622
chr203972585939725890+CDS,intron-Proximal3.5251813.26331HepG2BCLAF1
chr203972111139721161+CDS,intron-Proximal4.4454037.34663K562UCHL5
chr203970623439706275+CDS3.4835318.77833K562ZNF800
chr203972878939728863+CDS3.4502129.17809K562PUM1
chr203965773939657743+CDS,intron-Proximal4.142619.84476K562AQR
chr203972600839726127+intron-Distal,intron-Proximal4.3991713.59642K562KHSRP
chr203972088939720949+intron-Distal3.190575.58362HepG2U2AF2
chr203973567139735715+intron-Distal3.214503.69184HepG2SUGP2
chr203972606739726105+intron-Distal,intron-Proximal3.780453.20552HepG2KHSRP
chr203969303739693102+intron-Distal4.489464.66737HepG2MATR3
chr203966315239663208+intron-Distal4.346054.48560K562EXOSC5
chr203966321139663263+intron-Distal3.169613.39857HepG2HNRNPM
chr203971037439710466+intron-Distal3.647354.19039HepG2PTBP1
chr203966216039662227+intron-Distal5.298167.71339HepG2RBFOX2
chr203970630739706389+intron-Distal,intron-Proximal4.843058.63085K562RBM22
chr203966352639663586+intron-Distal4.0889512.67419HepG2HNRNPC
chr203969421439694269+intron-Distal3.983376.39777K562PTBP1
chr203970950739709556+intron-Distal4.020054.77518HepG2U2AF2
chr203967396039674003+intron-Distal3.278413.44195K562TARDBP
chr203966214939662234+intron-Distal3.7682110.86198K562RBFOX2
chr203965843239658498+intron-Distal3.450388.84888HepG2PTBP1
chr203971417439714227+intron-Distal3.868263.24603K562KHSRP
chr203972205239722239+intron-Distal3.034168.43690HepG2PTBP1
chr203969399439694042+intron-Distal3.300534.14346HepG2SUGP2
chr203970955639709644+intron-Distal3.9362213.46806HepG2U2AF2
chr203972204739722182+intron-Distal5.3698174.97786HepG2PCBP2
chr203969282839692880+intron-Distal3.054203.27745HepG2SUGP2
chr203972565639725706+intron-Distal4.350008.75493K562KHSRP
chr203972079239720903+intron-Distal3.439885.57010K562KHSRP
chr203969315939693231+intron-Distal4.4363010.31671HepG2SUGP2
chr203973797039738103+intron-Distal3.465323.12625HepG2QKI
chr203970964439709711+intron-Distal,intron-Proximal3.447865.58362HepG2U2AF2
chr203972205539722167+intron-Distal5.4492011.12473HepG2HNRNPK
chr203969678939696896+intron-Distal3.275934.61989HepG2SUGP2
chr203972203939722148+intron-Distal3.830407.10700K562PCBP1
chr203975012239750168+intron-Distal4.566614.12401HepG2U2AF2
chr203969288039692976+intron-Distal3.835937.98306HepG2SUGP2
chr203969631539696392+intron-Distal3.026313.95507HepG2SUGP2
chr203970230939702406+intron-Distal3.172843.12625HepG2QKI
chr203972672939726758+intron-Distal,intron-Proximal3.616374.57751HepG2U2AF2
chr203966386639663925+intron-Distal3.475104.02462K562TIA1
chr203965842539658496+intron-Distal3.713869.96429K562PTBP1
chr203969657039696612+intron-Distal3.265553.84025HepG2SUGP2
chr203974286139742903+intron-Distal,intron-Proximal3.738343.88924K562PRPF8
chr203969417339694273+intron-Distal4.494309.54872HepG2PTBP1
chr203971427739714357+intron-Distal3.391289.19790HepG2U2AF2
chr203972204439722213+intron-Distal4.2250411.50095K562PTBP1
chr203965893339659008+intron-Distal3.676589.07592HepG2HNRNPM
chr203973528039735314+intron-Distal4.062554.10688K562KHSRP
chr203972570639725762+intron-Distal,intron-Proximal4.0146111.22001K562KHSRP
chr203972612939726184+intron-Distal3.747899.59587HepG2U2AF2
chr203965997639660024+intron-Distal3.840307.21600HepG2HNRNPM
chr203969222039692281+intron-Distal4.683845.76606K562EXOSC5
chr203969479239694818+intron-Distal3.767793.29248HepG2SUGP2
chr203965846139658500+intron-Distal4.051105.21358K562TIA1
chr203967390139673960+intron-Distal4.682095.08344K562TARDBP
chr203972220239722264+intron-Distal6.3323917.27708HepG2PCBP2
chr203972540239725491+intron-Distal3.083438.81026HepG2PCBP2
chr203973535839735434+intron-Distal5.178578.95887HepG2HNRNPM
chr203971517739715244+intron-Distal3.813894.94813HepG2HNRNPM
chr203969159639691651+intron-Distal3.749706.25586HepG2SUGP2
chr203969291039692979+intron-Distal4.328503.62238HepG2MATR3
chr203966232039662392+intron-Distal4.507406.38702K562HNRNPL
chr203965888439658933+intron-Distal5.040158.05797HepG2HNRNPM
chr203969281839692883+intron-Distal4.014993.30696K562EXOSC5
chr203973644039736502+intron-Distal3.635803.97268K562PTBP1
chr203966337139663465+intron-Distal3.509277.19702K562KHSRP
chr203966143039661539+intron-Distal3.047173.49029HepG2SFPQ
chr203972106239721094+intron-Proximal3.869654.84268K562SF3B4
chr203965775139657777+intron-Proximal5.617208.16909HepG2AQR
chr203965774339657809+intron-Proximal4.653079.59600K562AQR
chr203970990139709940+intron-Proximal3.304773.40525HepG2AGGF1
chr203970630639706355+intron-Proximal3.763885.38516HepG2RBM22
chr203965774839657788+intron-Proximal3.9594614.09734HepG2PRPF8
chr203970628139706355+intron-Proximal4.3801114.13124HepG2PRPF8
chr203965798239658030+intron-Proximal4.363686.96160K562SF3B4
chr203970973539709780+intron-Proximal4.158853.27601HepG2RBM5
chr203972598339726019+intron-Proximal5.331155.69951K562AQR
chr203969015739690202+intron-Proximal4.832364.40230HepG2RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TOP1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TOP1 is not available on ENCORE database.

  • 103 RBPs can affect the levels of TOP1.  








The Knockdown/knockout RNA-Seq assay for TOP1 is not available on ENCORE database.





103 RBPs can affect the gene expression of TOP1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TOP1ENSG00000198900.52995.097902267.909900.401104.211002.91710HepG2AATF
TOP1ENSG00000198900.55322.222603630.030300.551908.979308.01170HepG2ACO1
TOP1ENSG00000198900.52314.248003098.99940-0.421304.097702.91080HepG2ADAR
TOP1ENSG00000198900.54531.783905079.38060-0.164601.975301.37810HepG2AUH
TOP1ENSG00000198900.56487.983604186.921600.631804.784703.80430HepG2CALR
TOP1ENSG00000198900.54109.478407518.85020-0.871605.043203.70840HepG2CCAR1
TOP1ENSG00000198900.53155.098203629.57820-0.202103.222802.51490HepG2CKAP4
TOP1ENSG00000198900.54085.375602999.092200.445802.428601.71510HepG2CNOT7
TOP1ENSG00000198900.54384.595005939.92220-0.438004.999304.09870HepG2CPSF6
TOP1ENSG00000198900.52743.066903178.01750-0.212302.248601.33310HepG2YBX3
TOP1ENSG00000198900.53262.088402321.312000.490803.452601.87230HepG2CSTF2T
TOP1ENSG00000198900.56095.104804735.214700.364107.001406.06740HepG2CELF1
TOP1ENSG00000198900.54079.008905091.66240-0.319908.422507.23730HepG2DAZAP1
TOP1ENSG00000198900.52621.338803357.41280-0.357007.646506.37540HepG2DDX19B
TOP1ENSG00000198900.54178.856103269.468200.354002.460801.87580HepG2DDX6
TOP1ENSG00000198900.52045.497203473.04240-0.7637019.9884018.55740HepG2DKC1
TOP1ENSG00000198900.52143.717603120.48530-0.5417011.6351010.27450HepG2DNAJC21
TOP1ENSG00000198900.52722.188603093.06080-0.184302.673002.03040HepG2DNAJC2
TOP1ENSG00000198900.53975.581302509.062600.663909.342507.77920HepG2EIF3D
TOP1ENSG00000198900.55104.100403381.879900.593704.912204.01250HepG2EIF4B
TOP1ENSG00000198900.53227.244104811.84340-0.576308.185406.81700HepG2EIF4G2
TOP1ENSG00000198900.55192.809805831.77460-0.167401.830801.32080HepG2ETF1
TOP1ENSG00000198900.51729.837602385.42900-0.463603.786502.47890HepG2FASTKD2
TOP1ENSG00000198900.56649.275005093.981400.384302.006801.34570HepG2FIP1L1
TOP1ENSG00000198900.53337.307502017.213100.726208.999307.62250HepG2FUBP3
TOP1ENSG00000198900.51455.018702234.02450-0.618607.112805.69020HepG2GEMIN5
TOP1ENSG00000198900.54526.145406733.31890-0.573006.462105.51120HepG2GPKOW
TOP1ENSG00000198900.51871.673803150.38180-0.7512014.3224013.03660HepG2HNRNPA1
TOP1ENSG00000198900.52499.650503504.26060-0.487406.331105.31640HepG2HNRNPC
TOP1ENSG00000198900.53370.322304921.95380-0.5463013.6996012.26350HepG2HNRNPF
TOP1ENSG00000198900.53395.857004638.15850-0.4498014.3414012.91680HepG2HNRNPL
TOP1ENSG00000198900.54352.123206425.73440-0.562107.317006.35010HepG2HNRNPLL
TOP1ENSG00000198900.52183.113403481.08940-0.6732022.2258020.62490HepG2HNRNPU
TOP1ENSG00000198900.53013.345004846.76160-0.6857010.829009.49030HepG2IGF2BP1
TOP1ENSG00000198900.53102.190503555.81020-0.196903.185002.40390HepG2ILF2
TOP1ENSG00000198900.52823.986603318.51230-0.232803.488202.34400HepG2KIF1C
TOP1ENSG00000198900.54484.709003525.384500.347102.486301.88490HepG2MATR3
TOP1ENSG00000198900.53274.464906553.51370-1.0010011.774509.76750HepG2MTPAP
TOP1ENSG00000198900.54165.747405048.87430-0.277403.516502.65750HepG2NOL12
TOP1ENSG00000198900.55312.339902741.351100.954408.166206.59410HepG2PABPC1
TOP1ENSG00000198900.54220.492503189.716100.403909.148208.14890HepG2PCBP1
TOP1ENSG00000198900.52398.217403104.84600-0.372605.767104.73600HepG2PPIL4
TOP1ENSG00000198900.54663.688503245.778600.5228014.9793013.90350HepG2PTBP1
TOP1ENSG00000198900.52852.199804819.55220-0.7568016.0086014.73510HepG2PUF60
TOP1ENSG00000198900.56477.841205116.120400.3404010.096909.11240HepG2PUM1
TOP1ENSG00000198900.53936.718505112.41260-0.377005.658204.71180HepG2PUM2
TOP1ENSG00000198900.55173.370903514.995800.5575012.5166011.32910HepG2QKI
TOP1ENSG00000198900.57288.519303188.271701.192809.728208.45960HepG2RAVER1
TOP1ENSG00000198900.57570.810904874.291500.6352019.1039017.99220HepG2RBM22
TOP1ENSG00000198900.54577.084003190.183800.520705.300304.39570HepG2RBM25
TOP1ENSG00000198900.52560.136003196.73670-0.320402.248301.36350HepG2RBM27
TOP1ENSG00000198900.54086.546802896.799900.496303.420101.72370HepG2RBM47
TOP1ENSG00000198900.53778.629805301.51880-0.488505.634604.71080HepG2RPLP0
TOP1ENSG00000198900.52357.800603012.09600-0.353302.004401.32350HepG2RPS3A
TOP1ENSG00000198900.53667.639103009.502900.285202.566501.53340HepG2RPS5
TOP1ENSG00000198900.53733.344502553.330700.548006.004104.89340HepG2RRP9
TOP1ENSG00000198900.56186.834304858.565900.348601.953001.38410HepG2SF3A3
TOP1ENSG00000198900.53845.485304621.10260-0.265105.662404.71910HepG2SLBP
TOP1ENSG00000198900.53979.693203615.125700.138501.914001.36250HepG2SMN1
TOP1ENSG00000198900.55061.976207076.82640-0.483403.145302.31050HepG2SNRNP70
TOP1ENSG00000198900.57770.378605505.345400.4971017.7737016.79520HepG2SRFBP1
TOP1ENSG00000198900.55781.781503527.090500.7129031.0290029.82170HepG2SRSF1
TOP1ENSG00000198900.53268.352504835.51120-0.565107.412806.36160HepG2SRSF7
TOP1ENSG00000198900.53483.859902869.553700.279804.887404.19230HepG2SRSF9
TOP1ENSG00000198900.53526.358904779.96520-0.4388011.5048010.59890HepG2SSB
TOP1ENSG00000198900.56236.839705411.829900.204603.593502.90270HepG2SUCLG1
TOP1ENSG00000198900.51963.281703170.53670-0.6915017.5839016.34490HepG2TAF15
TOP1ENSG00000198900.51963.039703382.36630-0.7849019.2376018.13670HepG2TIAL1
TOP1ENSG00000198900.56281.858004358.759600.527203.858903.12140HepG2U2AF1
TOP1ENSG00000198900.51512.390101967.31100-0.379402.658401.91420HepG2UCHL5
TOP1ENSG00000198900.51915.751803049.89160-0.670804.798703.45990HepG2UPF2
TOP1ENSG00000198900.55164.254604428.814500.221503.015001.92700HepG2UTP18
TOP1ENSG00000198900.53641.676304159.97900-0.192002.716902.12420HepG2UTP3
TOP1ENSG00000198900.51853.892803278.05150-0.8223011.050109.61890HepG2XRN2
TOP1ENSG00000198900.58130.692606960.111300.224204.057103.39330K562AGGF1
TOP1ENSG00000198900.56414.191907766.67630-0.276002.359801.81130K562AQR
TOP1ENSG00000198900.57527.933109306.47570-0.306005.409903.82340K562CPEB4
TOP1ENSG00000198900.56085.878407134.16790-0.229302.273901.55630K562CPSF6
TOP1ENSG00000198900.515313.7361012309.533100.315004.571103.30700K562CELF1
TOP1ENSG00000198900.53463.649504279.86770-0.305303.166702.04550K562DDX3X
TOP1ENSG00000198900.511943.389509629.697600.310506.521105.58020K562DDX47
TOP1ENSG00000198900.54030.243204701.31190-0.222202.875101.63730K562EIF2S1
TOP1ENSG00000198900.55458.345306645.25170-0.283903.485702.69370K562EIF2S2
TOP1ENSG00000198900.53314.407604471.49730-0.432005.137604.01760K562EIF4A3
TOP1ENSG00000198900.55603.647107187.54010-0.359103.823802.81600K562FIP1L1
TOP1ENSG00000198900.54836.608803881.178200.317404.100902.43010K562FUS
TOP1ENSG00000198900.56366.494404975.336300.355602.229201.60440K562G3BP2
TOP1ENSG00000198900.56072.297308856.03360-0.544407.170905.94320K562GRSF1
TOP1ENSG00000198900.52662.749004587.21370-0.7847017.3916015.97830K562HNRNPC
TOP1ENSG00000198900.53283.596104095.98780-0.318903.224701.98360K562HNRNPF
TOP1ENSG00000198900.56985.193809745.19830-0.480406.102704.93190K562HSPD1
TOP1ENSG00000198900.510000.777007685.740500.379803.846902.85150K562KIF1C
TOP1ENSG00000198900.510701.455808610.003100.313603.564302.51270K562MBNL1
TOP1ENSG00000198900.55528.817406785.03210-0.295406.220505.04900K562MTPAP
TOP1ENSG00000198900.56729.325505392.153500.319503.301702.23290K562PCBP2
TOP1ENSG00000198900.56381.303408158.84800-0.354503.397302.47270K562PPIG
TOP1ENSG00000198900.54959.140803992.286800.312802.916002.14740K562PRPF8
TOP1ENSG00000198900.53343.897904112.80640-0.298602.624001.74670K562PSIP1
TOP1ENSG00000198900.510956.724407181.978100.609309.681808.71540K562PUS1
TOP1ENSG00000198900.56851.408404747.345500.529203.156401.62740K562RAVER1
TOP1ENSG00000198900.59216.577406998.147800.397207.841206.87380K562RBM15
TOP1ENSG00000198900.53084.371103751.86690-0.282602.892301.87820K562RCC2
TOP1ENSG00000198900.55222.698404067.050000.360703.061902.20150K562RPS19
TOP1ENSG00000198900.56487.119507438.85720-0.197502.147501.42140K562SF3A3
TOP1ENSG00000198900.54842.491108309.96890-0.779103.879002.22900K562SFPQ
TOP1ENSG00000198900.52583.078403556.72500-0.461505.546903.94870K562SRFBP1
TOP1ENSG00000198900.59484.319007621.271200.315406.759305.36800K562SRPK2
TOP1ENSG00000198900.55784.118104761.087800.280703.340002.43830K562SYNCRIP
TOP1ENSG00000198900.54012.787305841.63130-0.541806.942105.77170K562TARDBP
TOP1ENSG00000198900.54393.146305634.84140-0.359104.635003.53490K562TIA1
TOP1ENSG00000198900.52916.820003955.89690-0.439604.154902.98760K562TIAL1
TOP1ENSG00000198900.53478.668504202.03070-0.272602.290201.44230K562TRIM56
TOP1ENSG00000198900.56925.309208155.99350-0.236004.028102.49380K562TROVE2
TOP1ENSG00000198900.58843.643807112.607200.314207.979006.61230K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TOP1 is not available on ENCORE database.





1 RBPs can affect the splicing of TOP1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETOP1ENSG00000198900.5chr20+3972546539725653397210903972122739725859397259810.101000.000000.00000includedK562AQR
A3SSTOP1ENSG00000198900.5chr20+3975060539750795397506453975079539750335397504300.074000.000000.00000longerK562AQR
MXETOP1ENSG00000198900.5chr20+3972109039721227397254653972565339713075397132083972585939725981-0.160000.000000.000002includedK562AQR
MXETOP1ENSG00000198900.5chr20+3972105139721227397254653972565339713075397132083972585939725981-0.156000.000000.000002includedK562AQR
MXETOP1ENSG00000198900.5chr20+3972106939721227397254653972565339713075397132083972585939725981-0.160000.000000.000002includedK562AQR
MXETOP1ENSG00000198900.5chr20+3972111139721227397254653972565339713075397132083972585939725981-0.072000.000000.000002includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TOP1 is not avaliable on ENCORE database.