TOMM40

General Information

Gene Name       : TOMM40
Gene ID             : ENSG00000130204.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TOMM40)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TOMM40ENSG00000130204.1212.2949.3630.82ENCSR000AEF
HepG2TOMM40ENSG00000130204.12118.6257.3587.98ENCSR985KAT
K562TOMM40ENSG00000130204.12144.70107.37126.03ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TOMM40 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TOMM40 RNA is bound by 20 proteins.  







eCLIP assay for TOMM40 is not avaliable on ENCORE database.





20 proteins are bound to TOMM40 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr194539459645394717+3'-UTR,5'-UTR,CDS,intron-Proximal3.1804415.60914HepG2BUD13
chr194540680745406870+3'-UTR3.257006.74785K562UPF1
chr194539460345394684+3'-UTR,5'-UTR,CDS,intron-Proximal3.067275.56719K562SF3B4
chr194539466145394756+3'-UTR,5'-UTR,CDS,intron-Proximal4.2190124.20352HepG2DDX3X
chr194540465345404700+3'-UTR,intron-Distal,intron-Proximal4.111793.69388HepG2XPO5
chr194540688445406935+3'-UTR5.315698.76702K562CPEB4
chr194540623945406252+3'-UTR,intron-Proximal4.8412614.55218HepG2SF3B4
chr194540680745406860+3'-UTR3.265397.46947HepG2PCBP2
chr194540452245404638+3'-UTR,CDS,intron-Proximal5.0132223.46466HepG2PRPF8
chr194540666945406729+3'-UTR3.639378.77854K562PABPC4
chr194540661045406678+3'-UTR5.7399610.25977HepG2UPF1
chr194540679945406859+3'-UTR3.558133.37567HepG2HNRNPK
chr194540649045406550+3'-UTR4.475514.53890K562PCBP1
chr194540547245405540+3'-UTR,intron-Distal3.948289.32329HepG2ILF3
chr194540667845406823+3'-UTR6.8524123.96021HepG2UPF1
chr194540625245406277+3'-UTR,intron-Proximal3.9004213.26517HepG2SF3B4
chr194540456345404626+3'-UTR,CDS,intron-Proximal3.529185.32296K562PRPF8
chr194540656545406623+3'-UTR3.378664.14964K562UPF1
chr194540647645406573+3'-UTR4.5230110.22562HepG2UPF1
chr194539466345394732+3'-UTR,5'-UTR,CDS,intron-Proximal3.073223.58112K562DDX3X
chr194540458245404613+3'-UTR,CDS,intron-Proximal4.012855.47926K562AQR
chr194540681645406861+3'-UTR3.022018.62245K562PABPC4
chr194539451945394574+5'-UTR,intron-Distal,intron-Proximal3.590277.31899HepG2DDX3X
chr194539459845394662+5'-UTR,intron-Proximal5.5521511.57871K562BUD13
chr194539451245394577+5'-UTR,intron-Distal,intron-Proximal3.386233.33365K562DDX3X
chr194539494445394960+CDS,intron-Proximal5.395797.63570K562AQR
chr194539473245394771+CDS3.591693.24636K562DDX3X
chr194539475645394822+CDS5.1494413.83562HepG2DDX3X
chr194540398845404096+CDS3.107147.36517K562DDX24
chr194539725745397326+CDS,intron-Proximal3.314095.23557K562DDX24
chr194539603545396140+CDS,intron-Proximal5.435877.81477K562SF3B4
chr194539570945395725+CDS,intron-Proximal5.1383311.51106K562PRPF8
chr194539566045395702+CDS4.081887.70480K562YBX3
chr194539560045395665+CDS,intron-Proximal3.283707.01463HepG2BUD13
chr194539561845395666+CDS,intron-Proximal5.225115.58036HepG2EFTUD2
chr194539728745397355+CDS,intron-Proximal5.3150525.37826HepG2PRPF8
chr194539493745394990+CDS,intron-Proximal4.406528.47952HepG2PRPF8
chr194539724245397338+CDS,intron-Proximal3.227776.92518HepG2PPIG
chr194539609545396175+CDS3.877083.79347HepG2GRWD1
chr194540393345403994+CDS,intron-Proximal4.4456510.68651K562SF3B4
chr194539706745397118+CDS3.479854.53005K562YBX3
chr194539616945396186+CDS4.173684.08604HepG2PPIG
chr194539569145395790+CDS,intron-Proximal5.4539622.62936HepG2PRPF8
chr194539559545395682+CDS,intron-Proximal3.103373.89662K562BUD13
chr194539570445395717+CDS3.6825612.23319K562YBX3
chr194539712245397178+CDS,intron-Proximal6.2334712.84241HepG2PRPF8
chr194539560045395669+CDS,intron-Proximal4.749158.25856K562SF3B4
chr194539556745395666+CDS,intron-Proximal4.241923.70701HepG2PRPF4
chr194539609345396127+CDS,intron-Proximal3.4382310.59168K562YBX3
chr194539477145394824+CDS3.124534.32969K562DDX3X
chr194539825545398401+intron-Distal3.358865.13070HepG2HNRNPM
chr194539579145395845+intron-Distal,intron-Proximal3.146215.54603K562PRPF8
chr194539740445397457+intron-Distal,intron-Proximal5.393065.02942K562EFTUD2
chr194539503745395062+intron-Distal,intron-Proximal3.510923.54718K562PRPF8
chr194540411445404162+intron-Proximal4.269435.64484HepG2PRPF8
chr194539557945395648+intron-Proximal3.798783.05889HepG2SF3B4
chr194539572545395755+intron-Proximal6.5045915.26945K562PRPF8
chr194540391145403976+intron-Proximal4.667745.31973HepG2SF3B4
chr194539496045394987+intron-Proximal4.492117.92018K562AQR
chr194539575545395791+intron-Proximal5.646217.96842K562PRPF8
chr194539499745395042+intron-Proximal4.309434.67744K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TOMM40 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TOMM40 is not available on ENCORE database.

  • 112 RBPs can affect the levels of TOMM40.  








The Knockdown/knockout RNA-Seq assay for TOMM40 is not available on ENCORE database.





112 RBPs can affect the gene expression of TOMM40 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TOMM40ENSG00000130204.8613.08090954.30670-0.638406.284504.73780HepG2AATF
TOMM40ENSG00000130204.81208.074801684.03100-0.479204.057403.34710HepG2ACO1
TOMM40ENSG00000130204.81219.423401691.63580-0.472203.680002.80750HepG2AKAP8L
TOMM40ENSG00000130204.81949.802901080.388600.851704.851504.08750HepG2BOP1
TOMM40ENSG00000130204.81213.753201549.84750-0.352703.526202.14400HepG2BUD13
TOMM40ENSG00000130204.8833.467101110.67870-0.414202.284701.57840HepG2CALR
TOMM40ENSG00000130204.81219.074501719.40410-0.496103.415902.32220HepG2CCAR1
TOMM40ENSG00000130204.81107.402201433.76500-0.372601.991801.32870HepG2CIRBP
TOMM40ENSG00000130204.8890.79320651.540300.451102.077701.41930HepG2CNOT7
TOMM40ENSG00000130204.8631.06260991.80530-0.652303.452602.69210HepG2CPSF6
TOMM40ENSG00000130204.81295.19100957.915100.435104.365703.08760HepG2YBX3
TOMM40ENSG00000130204.81964.189001585.636300.308803.907803.16760HepG2CELF1
TOMM40ENSG00000130204.8741.206301052.24830-0.505504.738403.87690HepG2DDX21
TOMM40ENSG00000130204.8667.543701030.23760-0.626007.443505.95750HepG2DDX24
TOMM40ENSG00000130204.81060.272301746.98680-0.720404.390503.61710HepG2DDX3X
TOMM40ENSG00000130204.81199.410201611.06580-0.425702.541401.88900HepG2DKC1
TOMM40ENSG00000130204.8621.08860969.41520-0.642304.838503.37090HepG2AGO1
TOMM40ENSG00000130204.81100.783101442.63870-0.390202.115901.58980HepG2EIF2S1
TOMM40ENSG00000130204.81364.718001792.09110-0.393003.797102.52940HepG2ESF1
TOMM40ENSG00000130204.82133.569702699.57410-0.339505.952905.12680HepG2ETF1
TOMM40ENSG00000130204.82069.256901645.271200.330702.515801.71860HepG2EWSR1
TOMM40ENSG00000130204.81538.501602089.27300-0.441503.110102.29880HepG2FIP1L1
TOMM40ENSG00000130204.8930.698501467.03620-0.656504.274203.30890HepG2FUBP3
TOMM40ENSG00000130204.82142.966701609.144400.413203.372702.61260HepG2FXR1
TOMM40ENSG00000130204.8621.17600949.53260-0.612206.091005.18420HepG2HNRNPA1
TOMM40ENSG00000130204.81169.159001566.87370-0.422406.231104.92520HepG2HNRNPA2B1
TOMM40ENSG00000130204.8753.297501072.81050-0.510102.343501.75910HepG2HNRNPLL
TOMM40ENSG00000130204.82763.367201618.578500.771609.209308.11260HepG2MATR3
TOMM40ENSG00000130204.81308.201201690.41470-0.369803.844502.89500HepG2MSI2
TOMM40ENSG00000130204.81016.703401419.56860-0.481603.010201.74420HepG2NAA15
TOMM40ENSG00000130204.81047.999901656.59050-0.660604.381303.59260HepG2NCBP2
TOMM40ENSG00000130204.8987.846501474.77570-0.578103.428802.63070HepG2PABPC4
TOMM40ENSG00000130204.8854.827501358.05840-0.6678013.2610011.75930HepG2PRPF4
TOMM40ENSG00000130204.8740.243601029.20920-0.475502.567301.78820HepG2PRPF8
TOMM40ENSG00000130204.81404.000201641.33530-0.225302.014101.53420HepG2PTBP1
TOMM40ENSG00000130204.82187.977001713.153400.352807.354806.48300HepG2PUM1
TOMM40ENSG00000130204.81346.950401777.47810-0.400104.807404.01750HepG2QKI
TOMM40ENSG00000130204.81170.50530508.748101.202003.354201.34380HepG2RBM17
TOMM40ENSG00000130204.81702.414102256.32420-0.406405.963905.27510HepG2RBM22
TOMM40ENSG00000130204.81007.440801613.22420-0.6793010.144708.91390HepG2RBM25
TOMM40ENSG00000130204.81344.977201701.31910-0.339104.397203.64380HepG2RECQL
TOMM40ENSG00000130204.81499.653802120.59080-0.499804.472703.63320HepG2RPLP0
TOMM40ENSG00000130204.8600.342001018.04530-0.761905.772704.67740HepG2RRP9
TOMM40ENSG00000130204.81304.59830934.364900.481408.292707.26710HepG2SAFB2
TOMM40ENSG00000130204.83109.415301898.327000.711803.845303.04490HepG2SF3A3
TOMM40ENSG00000130204.81421.500801089.589000.383506.478705.55980HepG2SMN1
TOMM40ENSG00000130204.8473.740501181.45720-1.318409.089907.68120HepG2SNRNP70
TOMM40ENSG00000130204.81317.811802548.39950-0.9514038.6234037.31670HepG2SRFBP1
TOMM40ENSG00000130204.82102.047201593.428000.399606.911105.98420HepG2SRSF5
TOMM40ENSG00000130204.8980.005701451.08530-0.5663010.963409.99350HepG2SRSF9
TOMM40ENSG00000130204.81578.899802212.55190-0.4868010.481709.60750HepG2SSB
TOMM40ENSG00000130204.82423.445401812.149400.419304.632003.86440HepG2SUCLG1
TOMM40ENSG00000130204.8742.895001328.71910-0.838806.082505.13810HepG2SUPV3L1
TOMM40ENSG00000130204.8847.594801603.28470-0.9196021.6615020.30050HepG2TAF15
TOMM40ENSG00000130204.8651.30960890.49370-0.451302.397201.46180HepG2TFIP11
TOMM40ENSG00000130204.8999.511601473.07030-0.559507.480006.12140HepG2TIA1
TOMM40ENSG00000130204.81432.352201028.648200.477508.133207.24670HepG2TRIM56
TOMM40ENSG00000130204.81879.467101576.657000.253402.093801.34320HepG2TUFM
TOMM40ENSG00000130204.81305.869401786.94900-0.452504.350403.57180HepG2U2AF1
TOMM40ENSG00000130204.82033.020201625.375400.322804.860004.10290HepG2UTP3
TOMM40ENSG00000130204.81039.704301340.22170-0.366305.319404.43820HepG2ZC3H8
TOMM40ENSG00000130204.81585.276401980.15870-0.320902.860102.19600K562AKAP8L
TOMM40ENSG00000130204.8963.663301315.88290-0.449403.701402.69100K562BOP1
TOMM40ENSG00000130204.82338.441602956.90910-0.338503.802502.02050K562CEBPZ
TOMM40ENSG00000130204.83999.054303480.619000.200202.380401.36110K562CPEB4
TOMM40ENSG00000130204.81085.470301399.21040-0.366303.316302.45540K562CPSF6
TOMM40ENSG00000130204.85235.521803601.866200.5395015.2456013.83200K562DDX47
TOMM40ENSG00000130204.82515.450002131.025700.239202.456701.63790K562DKC1
TOMM40ENSG00000130204.83129.082704072.00920-0.380006.794405.74140K562EIF2S2
TOMM40ENSG00000130204.82091.77840934.852701.1618037.0932034.17780K562EIF3G
TOMM40ENSG00000130204.82209.424201397.535000.660709.782708.22820K562EIF4A3
TOMM40ENSG00000130204.81285.118201849.21980-0.525003.432201.48390K562FAM120A
TOMM40ENSG00000130204.8619.364401000.13000-0.691305.900303.46830K562FASTKD2
TOMM40ENSG00000130204.83126.987102302.129200.441702.522101.71360K562FIP1L1
TOMM40ENSG00000130204.8950.898801819.25070-0.9360013.7549011.05520K562FKBP4
TOMM40ENSG00000130204.81027.540401423.56790-0.470304.345103.27310K562FMR1
TOMM40ENSG00000130204.8875.821801206.56080-0.462203.399602.37790K562FTO
TOMM40ENSG00000130204.8533.62990826.52330-0.631203.269801.80020K562FUS
TOMM40ENSG00000130204.83308.436201453.374501.1866050.4791048.09530K562FXR1
TOMM40ENSG00000130204.8144.42980539.96780-1.9025019.4278017.10440K562G3BP2
TOMM40ENSG00000130204.82425.533102997.86040-0.305603.973102.61400K562GLRX3
TOMM40ENSG00000130204.81645.061802094.48000-0.348503.500202.83920K562HNRNPC
TOMM40ENSG00000130204.83430.418801893.844200.857006.030204.59020K562HNRNPM
TOMM40ENSG00000130204.81367.267902025.88980-0.567303.049401.54960K562ILF2
TOMM40ENSG00000130204.81351.554301824.54320-0.432903.736002.01410K562KHDRBS1
TOMM40ENSG00000130204.81675.626302101.57360-0.326803.416202.48760K562KIF1C
TOMM40ENSG00000130204.8647.265901140.62360-0.817404.411203.20540K562KRR1
TOMM40ENSG00000130204.82024.511001097.274800.8835014.1093012.09210K562MAGOH
TOMM40ENSG00000130204.81587.763702011.61740-0.341403.607202.32670K562MAK16
TOMM40ENSG00000130204.81787.484501094.914800.707007.200005.61960K562MATR3
TOMM40ENSG00000130204.82572.700103151.82880-0.292904.917103.86290K562MTPAP
TOMM40ENSG00000130204.8979.583301395.54760-0.510604.526102.94220K562NCBP2
TOMM40ENSG00000130204.82731.187803502.13620-0.358708.472607.26800K562NSUN2
TOMM40ENSG00000130204.82124.267903547.44690-0.739808.317006.87740K562PCBP3
TOMM40ENSG00000130204.82031.675002720.87890-0.421404.388003.37550K562POLR2G
TOMM40ENSG00000130204.84286.586202613.819100.713606.278804.95890K562PPIG
TOMM40ENSG00000130204.82594.629402020.771800.360502.461101.75270K562PRPF8
TOMM40ENSG00000130204.82172.914401066.137001.0271021.0262019.26900K562PTBP1
TOMM40ENSG00000130204.84522.181805496.72280-0.281603.822802.68960K562PUM2
TOMM40ENSG00000130204.81448.135501964.04010-0.439604.349303.69110K562PUS1
TOMM40ENSG00000130204.81625.155201913.44080-0.235602.289901.74120K562RBM15
TOMM40ENSG00000130204.8941.202901611.89420-0.776203.434501.68140K562RBM39
TOMM40ENSG00000130204.81412.80540781.449100.854204.275102.99830K562RPS3
TOMM40ENSG00000130204.83149.757602424.789000.377302.888801.78180K562SAFB
TOMM40ENSG00000130204.8808.986701270.38370-0.651105.959504.49930K562SF3B1
TOMM40ENSG00000130204.8917.61460561.106200.709507.111805.70130K562SF3B4
TOMM40ENSG00000130204.82309.625301460.758700.660802.830801.50710K562SFPQ
TOMM40ENSG00000130204.81572.292201990.32160-0.340102.677101.43550K562SLBP
TOMM40ENSG00000130204.8454.85230858.41000-0.9163011.725808.26790K562SND1
TOMM40ENSG00000130204.82888.248803540.17010-0.293604.140303.01980K562SRPK2
TOMM40ENSG00000130204.81980.944401045.268600.9222011.313409.89400K562SRSF1
TOMM40ENSG00000130204.81116.13390754.345300.565106.076204.40500K562SRSF4
TOMM40ENSG00000130204.82540.518503032.57310-0.255402.955801.74540K562SRSF7
TOMM40ENSG00000130204.82330.285203096.86020-0.410304.528802.55640K562SRSF9
TOMM40ENSG00000130204.8660.69970964.33760-0.545503.884102.33030K562SSB
TOMM40ENSG00000130204.81016.179801645.99160-0.695803.099501.56000K562SUPT6H
TOMM40ENSG00000130204.81384.061701955.64530-0.498703.724102.52840K562SUPV3L1
TOMM40ENSG00000130204.83803.188702729.297400.478607.719906.33820K562SYNCRIP
TOMM40ENSG00000130204.8254.70070530.01150-1.057206.287503.66680K562TAF15
TOMM40ENSG00000130204.81470.299201057.667000.475103.355102.57380K562TARDBP
TOMM40ENSG00000130204.81446.203601020.295200.503203.722702.75410K562TIA1
TOMM40ENSG00000130204.84400.084605059.77670-0.201502.768201.49950K562TROVE2
TOMM40ENSG00000130204.8342.18510522.99340-0.612002.461601.44110K562U2AF1
TOMM40ENSG00000130204.8328.40840540.27280-0.718207.155605.87200K562U2AF2
TOMM40ENSG00000130204.81457.171502070.25930-0.506603.462202.31640K562UCHL5
TOMM40ENSG00000130204.82859.735003713.37570-0.376808.320407.15800K562UPF1
TOMM40ENSG00000130204.82186.951903177.44040-0.538905.720004.44070K562WDR3
TOMM40ENSG00000130204.83716.547603304.017300.169602.185601.42670K562WDR43
TOMM40ENSG00000130204.83008.057504374.37150-0.540203.484602.49740K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TOMM40 is not available on ENCORE database.





3 RBPs can affect the splicing of TOMM40 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RITOMM40ENSG00000130204.8chr19+454044644540470945404464454045674540464445404709-0.502000.001320.09963excludedK562TROVE2
RITOMM40ENSG00000130204.8chr19+4540446445404709454044644540456745404644454047090.481000.011380.06893includedHepG2SF3B4
MXETOMM40ENSG00000130204.8chr19+4539564945395717453960934539618645394663453949464539703645397138-0.083000.003320.025522includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TOMM40 is not avaliable on ENCORE database.