TOLLIP

General Information

Gene Name       : TOLLIP
Gene ID             : ENSG00000078902.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TOLLIP)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TOLLIPENSG00000078902.151.273.602.44ENCSR000AEF
HepG2TOLLIPENSG00000078902.1552.807.5830.19ENCSR985KAT
K562TOLLIPENSG00000078902.159.493.316.40ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TOLLIP is not avaliable on ENCORE database.



Proteins bound to RNA
  • TOLLIP RNA is bound by 22 proteins.  







eCLIP assay for TOLLIP is not avaliable on ENCORE database.





22 proteins are bound to TOLLIP RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1112961391296206-3'-UTR,intron-Distal3.247506.13685K562UPF1
chr1112968021296879-3'-UTR,intron-Distal,intron-Proximal4.200247.88159HepG2UPF1
chr1112961261296190-3'-UTR,intron-Distal3.249263.73678HepG2UPF1
chr1112975041297573-3'-UTR,intron-Distal4.828037.45692HepG2UPF1
chr1112980221298165-3'-UTR,intron-Distal,intron-Proximal6.0899417.47389HepG2UPF1
chr1112977311297793-3'-UTR,intron-Distal3.6780410.90748HepG2UPF1
chr1112979231297979-3'-UTR,intron-Distal,intron-Proximal3.228513.54552HepG2LARP4
chr1112980441298110-3'-UTR,intron-Distal,intron-Proximal4.975768.32932HepG2AKAP1
chr1112976731297806-3'-UTR,intron-Distal5.4928312.38649HepG2AKAP1
chr1112964871296569-3'-UTR,intron-Distal4.332174.93188HepG2UPF1
chr1112968011296863-3'-UTR,intron-Distal,intron-Proximal4.391365.18972HepG2AKAP1
chr1112976711297731-3'-UTR,intron-Distal3.336286.68047HepG2UPF1
chr1112967811296875-3'-UTR,intron-Distal,intron-Proximal4.6870015.52312K562UPF1
chr1112979561298028-3'-UTR,intron-Distal,intron-Proximal4.888856.23478HepG2AKAP1
chr1113238341323879-5'-UTR,intron-Distal3.069763.00221HepG2CSTF2T
chr1113307671330836-5'-UTR,intron-Distal,intron-Proximal4.9849311.73310HepG2DDX3X
chr1113240051324078-5'-UTR,intron-Distal,intron-Proximal3.435434.47051K562EWSR1
chr1113240021324095-5'-UTR,intron-Distal,intron-Proximal4.064443.63122HepG2PRPF4
chr1113307281330849-5'-UTR,intron-Distal,intron-Proximal3.250413.87702HepG2NCBP2
chr1113239991324081-5'-UTR,intron-Distal,intron-Proximal3.568983.52528HepG2FAM120A
chr1113168321316906-5'-UTR,CDS,intron-Distal,intron-Proximal3.813317.26133HepG2PRPF8
chr1113307071330767-5'-UTR,CDS,intron-Distal4.855347.51958HepG2DDX3X
chr1113071851307244-CDS,intron-Distal,intron-Proximal3.959985.64484HepG2PRPF8
chr1113071851307233-CDS,intron-Distal,intron-Proximal4.490833.93614HepG2AQR
chr1113073021307384-CDS,intron-Distal,intron-Proximal3.684344.57180HepG2AQR
chr1113097831309861-CDS,intron-Distal,intron-Proximal3.212334.78164HepG2PRPF8
chr1113098571309974-CDS,intron-Distal,intron-Proximal4.288098.74054HepG2PPIG
chr1113097611309855-CDS,intron-Distal,intron-Proximal4.369213.02711K562EWSR1
chr1113065181306566-intron-Distal3.919643.27946HepG2HNRNPM
chr1113126431312774-intron-Distal4.962446.89521K562AKAP8L
chr1113274601327549-intron-Distal,intron-Proximal3.407793.15535K562EWSR1
chr1113274551327520-intron-Distal,intron-Proximal3.384135.87066K562CSTF2T
chr1113279931328074-intron-Distal3.811514.41402K562DROSHA
chr1113146241314710-intron-Distal3.690894.45183HepG2CSTF2T
chr1113280021328114-intron-Distal3.394917.50411HepG2FAM120A
chr1113303201330399-intron-Distal4.418983.58113K562EWSR1
chr1113305421330584-intron-Distal3.910444.60097HepG2EFTUD2
chr1113125411312750-intron-Distal4.205393.84437HepG2PRPF4
chr1113063321306376-intron-Distal4.195534.61649HepG2CSTF2T
chr1113305951330677-intron-Distal3.921566.48652HepG2CSTF2T
chr1113109241310999-intron-Distal3.266903.46580HepG2CSTF2T
chr1113076711307806-intron-Distal4.465104.66439HepG2AKAP1
chr1113146521314720-intron-Distal3.244003.41462K562EWSR1
chr1113241391324194-intron-Distal4.090083.63902HepG2CSTF2T
chr1113073241307431-intron-Distal,intron-Proximal3.348083.33980HepG2SF3B4
chr1113279911328101-intron-Distal4.5847112.36962HepG2CSTF2T
chr1113305871330662-intron-Distal4.095925.72412HepG2FAM120A
chr1113270911327147-intron-Distal3.978753.30664K562NONO
chr1113126851312753-intron-Distal3.837573.43867K562CSTF2T
chr1113073361307397-intron-Distal,intron-Proximal4.324244.42197K562EWSR1
chr1113303321330407-intron-Distal3.067253.45174HepG2NKRF
chr1113295071329553-intron-Distal3.998543.80512K562CSTF2T
chr1113279671328103-intron-Distal5.3930911.90376K562CSTF2T
chr1113073641307436-intron-Distal,intron-Proximal4.760607.44133HepG2CSTF2T
chr1113096561309693-intron-Distal3.679184.21158HepG2CSTF2T
chr1113280121328113-intron-Distal4.714707.23918HepG2PRPF4
chr1113060731306113-intron-Distal3.040313.00221HepG2CSTF2T
chr1113241391324189-intron-Distal4.026833.80314K562CSTF2T
chr1113279711328118-intron-Distal4.968514.65580K562GTF2F1
chr1113304851330552-intron-Distal4.730456.05659HepG2CSTF2T
chr1113125051312580-intron-Distal3.924097.10319HepG2CSTF2T
chr1113094791309574-intron-Distal5.6416212.12716HepG2CSTF2T
chr1113090831309138-intron-Distal4.528776.08348HepG2CSTF2T
chr1113133511313440-intron-Distal,intron-Proximal4.430515.62460K562CSTF2T
chr1113085691308644-intron-Distal4.951316.70034HepG2CSTF2T
chr1113097631309824-intron-Distal,intron-Proximal4.058336.73995HepG2CSTF2T
chr1113225511322619-intron-Distal3.254883.28007HepG2NKRF
chr1113149861315067-intron-Distal4.774186.94957HepG2CSTF2T
chr1113196301319705-intron-Distal4.217134.43799HepG2CSTF2T
chr1113075981307645-intron-Distal4.129083.44758HepG2CSTF2T
chr1113274661327541-intron-Distal,intron-Proximal5.270038.83237HepG2CSTF2T
chr1113277971327849-intron-Distal3.922543.80512K562CSTF2T
chr1113068201306846-intron-Distal4.195534.61649HepG2CSTF2T
chr1113085861308647-intron-Distal5.5589210.50820HepG2FAM120A
chr1113062581306329-intron-Distal4.606815.84224K562EWSR1
chr1113062711306363-intron-Distal3.711674.19798K562SLTM
chr1113225591322618-intron-Distal4.255374.23759K562NONO
chr1113305841330669-intron-Distal4.3076413.42847HepG2EFTUD2
chr1113280021328098-intron-Distal4.785246.12846K562EWSR1
chr1113271651327196-intron-Distal3.836603.40229HepG2CSTF2T
chr1113305941330669-intron-Distal3.913163.30705HepG2GTF2F1
chr1113085541308637-intron-Distal4.659383.72302K562FTO
chr1113092361309297-intron-Distal4.989938.19768HepG2CSTF2T
chr1113093251309442-intron-Distal4.4341110.86370HepG2CSTF2T
chr1113071071307174-intron-Distal,intron-Proximal4.701275.93727HepG2CSTF2T
chr1113304141330453-intron-Distal3.279334.14880HepG2CSTF2T
chr1113065351306605-intron-Distal3.806065.08839HepG2CSTF2T
chr1113085261308638-intron-Distal4.315753.02711K562EWSR1
chr1113073511307431-intron-Distal,intron-Proximal5.4899210.20819HepG2FAM120A
chr1113062651306318-intron-Distal3.821688.38969HepG2CSTF2T
chr1113074691307557-intron-Distal3.407266.51348HepG2CSTF2T
chr1113061071306155-intron-Distal3.918983.28464K562EWSR1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TOLLIP is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TOLLIP is not available on ENCORE database.

  • 110 RBPs can affect the levels of TOLLIP.  








The Knockdown/knockout RNA-Seq assay for TOLLIP is not available on ENCORE database.





110 RBPs can affect the gene expression of TOLLIP :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TOLLIPENSG00000078902.111051.64750780.994900.429205.364604.33060HepG2AKAP8L
TOLLIPENSG00000078902.111481.188601075.832100.461204.453103.61850HepG2AUH
TOLLIPENSG00000078902.111224.90770472.498101.3742028.0092026.43690HepG2BOP1
TOLLIPENSG00000078902.111412.03830883.236600.676806.048904.93690HepG2CIRBP
TOLLIPENSG00000078902.111184.25290777.179000.6076012.1316010.93790HepG2CKAP4
TOLLIPENSG00000078902.11827.44440434.097200.930506.718305.52860HepG2CNOT7
TOLLIPENSG00000078902.11558.27390433.774500.363901.958201.36870HepG2CPSF6
TOLLIPENSG00000078902.11466.29000340.921100.451702.668201.67030HepG2YBX3
TOLLIPENSG00000078902.11737.28930503.650200.549706.434105.53180HepG2CELF1
TOLLIPENSG00000078902.11934.80390541.502400.7876016.4426014.89720HepG2DAZAP1
TOLLIPENSG00000078902.11954.07380718.921600.408205.424704.31030HepG2DDX19B
TOLLIPENSG00000078902.11514.99030341.368700.593105.240403.68590HepG2DDX1
TOLLIPENSG00000078902.11581.82490392.939400.566203.593402.82880HepG2DDX21
TOLLIPENSG00000078902.112418.904901076.159301.1684016.0608014.68240HepG2DDX3X
TOLLIPENSG00000078902.11914.20800583.902000.646706.483204.99240HepG2DDX5
TOLLIPENSG00000078902.11579.51650334.719200.791806.071505.06170HepG2DNAJC21
TOLLIPENSG00000078902.11629.12140331.821300.922807.905406.87440HepG2DNAJC2
TOLLIPENSG00000078902.11677.96180472.670000.520303.353102.34560HepG2EEF2
TOLLIPENSG00000078902.111333.42640888.674700.585303.928603.22970HepG2EIF2S1
TOLLIPENSG00000078902.11352.17190645.71480-0.8746010.657708.56560HepG2EIF2S2
TOLLIPENSG00000078902.112033.09020981.860801.050006.345805.38150HepG2EIF4A3
TOLLIPENSG00000078902.11753.24890511.784000.557504.722503.67620HepG2EIF4G2
TOLLIPENSG00000078902.111852.336101235.281000.584409.117508.13140HepG2ETF1
TOLLIPENSG00000078902.11553.29970361.505600.613904.027002.79630HepG2GNB2L1
TOLLIPENSG00000078902.11876.63290491.704900.834108.088207.03420HepG2GPKOW
TOLLIPENSG00000078902.11606.47230367.546900.722404.702402.87400HepG2HNRNPA0
TOLLIPENSG00000078902.11557.81010337.926500.723005.545504.67430HepG2HNRNPA1
TOLLIPENSG00000078902.11627.78790358.865100.806706.315604.11850HepG2HNRNPAB
TOLLIPENSG00000078902.11808.43310375.900001.104704.650103.76670HepG2HNRNPC
TOLLIPENSG00000078902.11917.84180581.325600.6588010.146708.88240HepG2HNRNPF
TOLLIPENSG00000078902.11742.16190493.253500.589308.410307.29370HepG2HNRNPL
TOLLIPENSG00000078902.11717.56760469.244200.612704.825004.01730HepG2HNRNPLL
TOLLIPENSG00000078902.11588.33460373.413300.655805.298104.48040HepG2HNRNPU
TOLLIPENSG00000078902.111024.85360572.438300.8401013.4173011.94660HepG2IGF2BP1
TOLLIPENSG00000078902.111369.22840934.275500.551303.786203.00660HepG2IGF2BP2
TOLLIPENSG00000078902.11541.28720381.426100.504905.454604.45350HepG2ILF2
TOLLIPENSG00000078902.11659.53190423.280700.639702.802101.47080HepG2ILF3
TOLLIPENSG00000078902.11857.61700710.584700.271202.580701.59490HepG2KIF1C
TOLLIPENSG00000078902.111515.38100752.355301.010109.234807.71090HepG2LARP4
TOLLIPENSG00000078902.111955.92440991.699200.979806.107105.14050HepG2MAGOH
TOLLIPENSG00000078902.111587.40320997.136800.670704.692103.88760HepG2MATR3
TOLLIPENSG00000078902.111899.136501020.533300.8959011.7800010.51570HepG2NCBP2
TOLLIPENSG00000078902.11923.61990536.955100.782407.293606.06850HepG2NOL12
TOLLIPENSG00000078902.11510.95870329.196500.634203.264801.68850HepG2NOLC1
TOLLIPENSG00000078902.11818.85660383.601001.093903.241102.05080HepG2NONO
TOLLIPENSG00000078902.11795.80000396.914101.003507.045205.58500HepG2PABPC1
TOLLIPENSG00000078902.111234.67360908.430000.442602.190601.54240HepG2PABPC4
TOLLIPENSG00000078902.11496.90710333.051500.577105.278104.28930HepG2PPIL4
TOLLIPENSG00000078902.111213.15490965.051900.330003.427902.83280HepG2PTBP1
TOLLIPENSG00000078902.111186.32880512.583101.2105024.3006022.77070HepG2PUF60
TOLLIPENSG00000078902.11717.90530544.144300.399704.444203.73200HepG2PUM1
TOLLIPENSG00000078902.111509.53510791.753300.9309027.9587026.37770HepG2PUS1
TOLLIPENSG00000078902.11612.48070427.159700.519803.043202.00280HepG2RBM27
TOLLIPENSG00000078902.11623.28500346.873600.845405.736704.20620HepG2RCC2
TOLLIPENSG00000078902.11905.52980626.252600.531903.314502.57720HepG2RPLP0
TOLLIPENSG00000078902.11836.49210366.494201.190505.642604.31790HepG2RPS10
TOLLIPENSG00000078902.11602.69090393.934600.613404.241403.25830HepG2RPS2
TOLLIPENSG00000078902.11802.53220436.356800.879006.255805.05900HepG2RPS3A
TOLLIPENSG00000078902.11611.77210402.143100.605204.088202.77010HepG2RPS5
TOLLIPENSG00000078902.11506.86760332.529800.608006.116105.21530HepG2SAFB2
TOLLIPENSG00000078902.112183.37940781.015701.4830023.8780021.84000HepG2SF3A3
TOLLIPENSG00000078902.11921.88670464.452000.9890013.6478012.20370HepG2SF3B1
TOLLIPENSG00000078902.11818.00200491.517400.7348013.0119011.68470HepG2SLBP
TOLLIPENSG00000078902.11604.20330387.766900.639708.261907.24440HepG2SMN1
TOLLIPENSG00000078902.11782.35390381.252801.037006.759105.21030HepG2SMNDC1
TOLLIPENSG00000078902.11330.84890516.78680-0.643403.121902.29100HepG2SNRNP70
TOLLIPENSG00000078902.111670.180001166.083300.5182010.069409.27550HepG2SRFBP1
TOLLIPENSG00000078902.11862.720401048.71170-0.281702.452602.00020HepG2SRSF1
TOLLIPENSG00000078902.11935.69940506.118700.8865017.8293016.43520HepG2SRSF5
TOLLIPENSG00000078902.11907.52190571.138400.6680010.536509.32910HepG2SRSF7
TOLLIPENSG00000078902.11520.90490853.19560-0.7119011.8230010.82300HepG2SRSF9
TOLLIPENSG00000078902.111842.852401012.383700.8641025.9926024.77830HepG2SSB
TOLLIPENSG00000078902.11693.69930379.739000.869207.452305.57840HepG2STIP1
TOLLIPENSG00000078902.11807.57650575.581400.488506.314205.44480HepG2SUCLG1
TOLLIPENSG00000078902.11888.60180580.329400.614606.519605.11470HepG2SUPT6H
TOLLIPENSG00000078902.11467.94970942.66400-1.0104019.1946017.90780HepG2TAF15
TOLLIPENSG00000078902.11585.23010457.400400.355401.951701.32920HepG2TARDBP
TOLLIPENSG00000078902.111174.63340362.768901.6950017.1496016.09780HepG2TIAL1
TOLLIPENSG00000078902.11681.57910366.089000.896603.103802.51450HepG2TRIM56
TOLLIPENSG00000078902.11782.66370500.795900.644102.171801.40340HepG2TUFM
TOLLIPENSG00000078902.111241.37890735.295600.755408.551307.44280HepG2U2AF1
TOLLIPENSG00000078902.111110.33760530.100301.0666012.9715011.11810HepG2UBE2L3
TOLLIPENSG00000078902.11474.45970245.180200.952302.647101.90580HepG2UCHL5
TOLLIPENSG00000078902.11994.23730692.642600.521403.320902.56720HepG2UPF1
TOLLIPENSG00000078902.11910.03820668.717600.444402.300601.74330HepG2UTP3
TOLLIPENSG00000078902.11897.75950390.871301.1995013.1240010.80020HepG2XPO5
TOLLIPENSG00000078902.11681.50790543.422400.326602.770902.09810HepG2ZC3H8
TOLLIPENSG00000078902.111226.48310761.772800.6870016.0869015.04100HepG2ZNF622
TOLLIPENSG00000078902.11583.85140374.294800.641306.833105.99900K562AGGF1
TOLLIPENSG00000078902.11654.16600411.286100.669406.448704.78610K562AKAP8
TOLLIPENSG00000078902.11650.36180389.468900.739605.148304.24540K562AKAP8L
TOLLIPENSG00000078902.111117.89520502.017601.154907.367706.48500K562AQR
TOLLIPENSG00000078902.11282.97540194.591700.540102.991801.99510K562BCLAF1
TOLLIPENSG00000078902.11289.99060172.000000.753504.118903.05140K562BOP1
TOLLIPENSG00000078902.11249.26650169.558900.555802.628601.38370K562CIRBP
TOLLIPENSG00000078902.11258.50560170.613300.599403.660302.11480K562DDX27
TOLLIPENSG00000078902.11539.40600335.405100.685407.523006.51970K562DDX47
TOLLIPENSG00000078902.11287.59610166.451500.788804.096302.96840K562EFTUD2
TOLLIPENSG00000078902.11317.46930178.118500.833704.263302.94270K562EIF3D
TOLLIPENSG00000078902.11386.98870206.169700.908407.637706.16090K562FIP1L1
TOLLIPENSG00000078902.11465.11790281.126700.726307.130706.22150K562FXR1
TOLLIPENSG00000078902.11269.74770174.607900.627403.181902.33250K562GPKOW
TOLLIPENSG00000078902.11651.29510413.391900.655705.690004.60220K562GRSF1
TOLLIPENSG00000078902.11357.56300216.201100.725704.810104.04350K562HNRNPC
TOLLIPENSG00000078902.11285.77840193.119400.565302.840701.68430K562HNRNPF
TOLLIPENSG00000078902.11296.76060158.290400.906605.241703.64560K562IGF2BP2
TOLLIPENSG00000078902.11256.19850160.967800.670403.896402.42890K562IGF2BP3
TOLLIPENSG00000078902.11526.76330413.330200.349802.007401.31310K562KIF1C
TOLLIPENSG00000078902.11303.46830166.270500.867906.584205.25960K562MAGOH
TOLLIPENSG00000078902.11548.02960395.653600.469903.068201.92300K562MAK16
TOLLIPENSG00000078902.11241.44640165.920100.541102.745901.82630K562MATR3
TOLLIPENSG00000078902.11481.34160310.338400.633102.378501.47480K562PABPN1
TOLLIPENSG00000078902.11378.44100234.046000.693204.752003.63470K562PPIG
TOLLIPENSG00000078902.11329.79940161.979001.025705.726304.64530K562PRPF8
TOLLIPENSG00000078902.11326.37600161.548701.014509.346508.17490K562PTBP1
TOLLIPENSG00000078902.111152.83820541.574201.089903.677902.73950K562PUF60
TOLLIPENSG00000078902.11704.75250386.259200.867409.125808.18790K562PUS1
TOLLIPENSG00000078902.11589.55070376.340700.647502.349201.79550K562RBM15
TOLLIPENSG00000078902.11249.74820154.858700.689403.867602.86230K562RBM22
TOLLIPENSG00000078902.11296.14360164.920900.844404.336703.30940K562RPS19
TOLLIPENSG00000078902.11333.43440158.381301.073909.348108.05950K562SRSF1
TOLLIPENSG00000078902.11269.81680149.603200.850705.626804.02770K562SRSF5
TOLLIPENSG00000078902.11246.69940156.700300.654602.657201.66160K562SUPV3L1
TOLLIPENSG00000078902.11372.76520160.271301.2177011.8821010.24020K562TARDBP
TOLLIPENSG00000078902.11286.09390154.605200.887806.398205.07800K562TIA1
TOLLIPENSG00000078902.11275.35590151.763200.859405.393703.75140K562TRA2A
TOLLIPENSG00000078902.11511.13070390.860000.386902.789502.06760K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TOLLIP is not available on ENCORE database.





2 RBPs can affect the splicing of TOLLIP :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETOLLIPENSG00000078902.11chr11-131687413170241311456131163913306951330820-0.117000.000630.02138excludedHepG2SF3A3
A3SSTOLLIPENSG00000078902.11chr11-1309853131006113098531310006131145613116390.115000.000000.00000longerK562AQR
A3SSTOLLIPENSG00000078902.11chr11-1298384129858312983841298483130723113073220.073000.000030.00026longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TOLLIP is not avaliable on ENCORE database.