RAC1

General Information

Gene Name       : RAC1
Gene ID             : ENSG00000136238.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: RAC1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RAC1ENSG00000136238.1799.76108.57104.16ENCSR000AEF
HepG2RAC1ENSG00000136238.17192.39188.04190.21ENCSR985KAT
K562RAC1ENSG00000136238.17159.27162.15160.71ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RAC1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • RAC1 RNA is bound by 23 proteins.  







eCLIP assay for RAC1 is not avaliable on ENCORE database.





23 proteins are bound to RAC1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr764432616443320+3'-UTR5.0672917.80807K562TIA1
chr764429936443085+3'-UTR4.177194.02104HepG2TIA1
chr764431506443249+3'-UTR3.5411540.37694K562PUM2
chr764433746443425+3'-UTR3.163499.70567K562PABPC4
chr764429526443009+3'-UTR3.460697.05728K562IGF2BP2
chr764427216442794+3'-UTR4.1549310.50859K562UPF1
chr764427296442792+3'-UTR3.0218013.10326K562FAM120A
chr764426226442697+3'-UTR3.349955.89531HepG2SUB1
chr764423466442390+3'-UTR4.6637913.08755K562IGF2BP2
chr764430406443092+3'-UTR4.2636112.79580K562TIA1
chr764427406442793+3'-UTR3.681343.34998HepG2IGF2BP3
chr764426176442666+3'-UTR3.654538.12495K562FAM120A
chr764433166443338+3'-UTR3.9667712.43329K562IGF2BP2
chr764430026443036+3'-UTR4.035927.97028K562TIA1
chr764426976442788+3'-UTR3.407737.93104HepG2SUB1
chr764434946443569+3'-UTR4.135263.80143K562NOLC1
chr764433796443430+3'-UTR3.183403.74671K562IGF2BP2
chr764423946442470+3'-UTR3.1127119.07857K562FAM120A
chr764433386443374+3'-UTR3.632468.60748K562IGF2BP2
chr764422316442272+3'-UTR3.089156.99606K562IGF2BP1
chr764435216443584+3'-UTR5.500158.51610HepG2SUB1
chr764427436442792+3'-UTR4.258023.83024HepG2IGF2BP1
chr764433906443414+3'-UTR4.059073.97489K562TIA1
chr764427416442791+3'-UTR3.7599310.27951K562IGF2BP2
chr764421596442201+3'-UTR5.3713256.06762K562PABPC4
chr764424706442617+3'-UTR3.3270927.41144K562FAM120A
chr764427036442786+3'-UTR4.5470114.16702K562IGF2BP1
chr764435026443579+3'-UTR4.004725.98925HepG2FUBP3
chr764429946443051+3'-UTR4.1002914.70562K562IGF2BP1
chr764433716443430+3'-UTR3.702237.62714HepG2SUB1
chr764423506442390+3'-UTR3.356827.93072K562TIA1
chr764433296443443+3'-UTR3.825333.66457HepG2IGF2BP3
chr764143346414403+5'-UTR,CDS,intron-Proximal4.6520917.24836K562DDX3X
chr764142076414307+5'-UTR4.0526810.20469HepG2DDX3X
chr764142106414307+5'-UTR5.2114214.31986K562DDX3X
chr764268906427037+CDS,intron-Distal,intron-Proximal4.1237910.62239K562PRPF8
chr764419466441956+CDS,intron-Proximal4.0640412.87748K562YBX3
chr764416506441658+CDS3.821256.80293K562YBX3
chr764314966431579+CDS,intron-Proximal3.577463.99381K562BUD13
chr764268426426856+CDS,intron-Proximal4.272527.62404K562DDX3X
chr764143756414402+CDS,intron-Proximal4.275194.38588HepG2DDX3X
chr764419566441978+CDS4.9862337.85036K562YBX3
chr764419786441999+CDS4.7958832.67231K562YBX3
chr764268426426856+CDS,intron-Proximal4.204924.17587HepG2DDX3X
chr764350826435130+intron-Distal3.372174.08043K562HNRNPM
chr764341036434195+intron-Distal3.146473.00129HepG2SUGP2
chr764351306435206+intron-Distal4.919427.65271K562HNRNPM
chr764327086432781+intron-Distal4.903797.06230K562EXOSC5
chr764387106438776+intron-Distal4.313896.98528HepG2HNRNPM
chr764341736434237+intron-Distal4.4703614.67846K562HNRNPM
chr764323226432390+intron-Distal4.940785.85485K562KHSRP
chr764386446438689+intron-Distal5.069608.23608HepG2HNRNPM
chr764342376434314+intron-Distal4.3671413.01688K562HNRNPM
chr764385816438632+intron-Distal3.318193.27704K562HNRNPM
chr764267136426759+intron-Distal,intron-Proximal4.042233.24603K562KHSRP
chr764352456435300+intron-Distal3.164773.14999K562EXOSC5
chr764342336434302+intron-Distal5.8508912.23409HepG2HNRNPM
chr764380146438066+intron-Distal3.145313.27704K562HNRNPM
chr764341766434233+intron-Distal4.8305710.82907HepG2HNRNPM
chr764386326438702+intron-Distal3.8659711.93587K562HNRNPM
chr764297436429825+intron-Distal5.160867.98841K562ILF3
chr764341546434176+intron-Distal4.127164.28420HepG2HNRNPM
chr764380076438064+intron-Distal3.040155.77148HepG2HNRNPM
chr764341016434154+intron-Distal4.6535416.23318HepG2HNRNPM
chr764295736429714+intron-Distal5.5361019.10934HepG2PCBP2
chr764145006414621+intron-Distal,intron-Proximal3.295954.14505K562RBFOX2
chr764387826438844+intron-Distal4.6601610.48177HepG2RBFOX2
chr764387116438782+intron-Distal6.0138314.98494HepG2RBFOX2
chr764387026438779+intron-Distal4.7288215.01741K562HNRNPM
chr764341136434173+intron-Distal6.1758316.32904K562HNRNPM
chr764350906435185+intron-Distal3.878416.29995HepG2HNRNPM
chr764412206441285+intron-Distal3.521723.02321K562U2AF2
chr764387796438837+intron-Distal5.6560110.81162K562HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RAC1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RAC1 is not available on ENCORE database.

  • 82 RBPs can affect the levels of RAC1.  








The Knockdown/knockout RNA-Seq assay for RAC1 is not available on ENCORE database.





82 RBPs can affect the gene expression of RAC1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RAC1ENSG00000136238.133070.931702331.376700.397404.174202.88560HepG2AATF
RAC1ENSG00000136238.134332.646902803.932700.6277023.0098021.64100HepG2ACO1
RAC1ENSG00000136238.136162.055904750.367500.375302.798902.26450HepG2AKAP1
RAC1ENSG00000136238.133201.440502817.162700.184402.091301.41140HepG2AKAP8L
RAC1ENSG00000136238.134087.689005582.96350-0.449703.308102.23440HepG2CCAR1
RAC1ENSG00000136238.133259.203002803.391100.217203.495102.76320HepG2CKAP4
RAC1ENSG00000136238.135624.458904132.047200.4448010.036008.95860HepG2CELF1
RAC1ENSG00000136238.131851.193402573.82480-0.475503.942603.14670HepG2DDX21
RAC1ENSG00000136238.132319.676102682.62130-0.209702.438701.79630HepG2DKC1
RAC1ENSG00000136238.132327.792202876.46380-0.305304.104903.26230HepG2DNAJC21
RAC1ENSG00000136238.133040.621102351.167600.370903.062802.11610HepG2EIF3D
RAC1ENSG00000136238.132854.259204152.64790-0.540905.050004.18970HepG2EIF4A3
RAC1ENSG00000136238.132710.657604043.33430-0.576904.575503.70320HepG2EIF4B
RAC1ENSG00000136238.135396.402404383.254000.299905.431804.32590HepG2EIF4G1
RAC1ENSG00000136238.133359.619704198.87210-0.321702.884302.05450HepG2EIF4G2
RAC1ENSG00000136238.133614.162102740.003400.399404.984103.86600HepG2EWSR1
RAC1ENSG00000136238.131729.615802101.45820-0.280902.709801.55530HepG2FAM120A
RAC1ENSG00000136238.136122.312004291.173000.512605.328404.29000HepG2FIP1L1
RAC1ENSG00000136238.133070.411802676.994200.197702.348601.44310HepG2HDGF
RAC1ENSG00000136238.132385.973502904.01900-0.283502.626901.99500HepG2HNRNPA1
RAC1ENSG00000136238.132355.061003230.12060-0.455805.545804.59140HepG2HNRNPC
RAC1ENSG00000136238.133400.678004004.09450-0.235703.347102.56340HepG2HNRNPF
RAC1ENSG00000136238.133283.985403936.01950-0.261302.029001.42480HepG2HNRNPK
RAC1ENSG00000136238.132463.297302961.15060-0.265602.209101.35870HepG2HNRNPM
RAC1ENSG00000136238.132653.516003208.76960-0.274104.400803.65130HepG2HNRNPU
RAC1ENSG00000136238.133170.701003942.88450-0.314403.828202.98690HepG2IGF2BP1
RAC1ENSG00000136238.132532.958203973.90800-0.649706.043704.50490HepG2KHSRP
RAC1ENSG00000136238.133160.628004414.54760-0.482103.332901.95870HepG2KRR1
RAC1ENSG00000136238.132784.763504191.54740-0.589906.837505.82070HepG2MAGOH
RAC1ENSG00000136238.133233.677104314.22360-0.415903.539702.82730HepG2NCBP2
RAC1ENSG00000136238.133602.311303176.212300.181502.097101.35210HepG2PARN
RAC1ENSG00000136238.133438.247803863.68530-0.168302.018401.48670HepG2PCBP1
RAC1ENSG00000136238.132447.769302861.97730-0.225502.422801.72960HepG2PPIL4
RAC1ENSG00000136238.132167.816902786.86480-0.362406.113905.01370HepG2PRPF4
RAC1ENSG00000136238.133115.868603931.39360-0.335405.704704.97640HepG2PTBP1
RAC1ENSG00000136238.132470.915902855.99730-0.208902.822102.20220HepG2PUS1
RAC1ENSG00000136238.132985.293304257.90450-0.5123010.252609.15760HepG2QKI
RAC1ENSG00000136238.133013.079104181.44390-0.472809.327808.50390HepG2RBM22
RAC1ENSG00000136238.133643.804804375.30570-0.263904.262303.61690HepG2NELFE
RAC1ENSG00000136238.133436.512204074.92620-0.245803.815903.10780HepG2RECQL
RAC1ENSG00000136238.133550.788304313.47350-0.280702.585601.92180HepG2RPLP0
RAC1ENSG00000136238.132854.504504180.74670-0.550504.327803.32670HepG2RPS3A
RAC1ENSG00000136238.133057.934002049.399600.577305.524604.44860HepG2RRP9
RAC1ENSG00000136238.132229.390102857.58880-0.358107.402306.42190HepG2SAFB2
RAC1ENSG00000136238.135591.596903430.717100.704705.123904.18730HepG2SF3A3
RAC1ENSG00000136238.132588.746004424.62250-0.773302.713402.01390HepG2SF3B1
RAC1ENSG00000136238.133307.544704032.48210-0.285905.997305.02670HepG2SLBP
RAC1ENSG00000136238.131829.765203332.49470-0.8649045.6272043.59980HepG2SMN1
RAC1ENSG00000136238.136558.176304722.851800.4735016.0840015.13840HepG2SRFBP1
RAC1ENSG00000136238.133768.172004272.35570-0.181202.464202.01110HepG2SRSF1
RAC1ENSG00000136238.133503.147403933.90960-0.167302.001301.39870HepG2SRSF7
RAC1ENSG00000136238.133245.602004100.66680-0.337406.246305.53300HepG2SSB
RAC1ENSG00000136238.134050.314902673.902800.599006.184005.23220HepG2SUPV3L1
RAC1ENSG00000136238.131692.844903118.15820-0.8812023.4867022.29640HepG2TIAL1
RAC1ENSG00000136238.132545.358003145.77580-0.305505.194504.47130HepG2TRIM56
RAC1ENSG00000136238.132860.760604108.65540-0.522308.484106.81720HepG2TUFM
RAC1ENSG00000136238.135026.875303671.204400.453305.410004.54760HepG2U2AF1
RAC1ENSG00000136238.131857.301002632.16700-0.503005.388404.38710HepG2XRN2
RAC1ENSG00000136238.133586.935902750.287000.383109.524208.40400HepG2ZC3H8
RAC1ENSG00000136238.134483.444903346.190500.4220013.7437012.75750HepG2ZNF622
RAC1ENSG00000136238.132181.211902932.53050-0.427002.767701.47180HepG2ZRANB2
RAC1ENSG00000136238.139027.163305790.522700.6405026.0008024.37550K562AGGF1
RAC1ENSG00000136238.137762.205806362.872000.286702.748001.77030K562AKAP8
RAC1ENSG00000136238.137233.139306025.292200.263502.407301.79750K562AKAP8L
RAC1ENSG00000136238.133393.934803986.24110-0.232103.564702.46970K562BCLAF1
RAC1ENSG00000136238.136347.200907310.83620-0.203902.800601.68940K562CPEB4
RAC1ENSG00000136238.134326.305207280.90850-0.751009.970608.47000K562CPSF6
RAC1ENSG00000136238.136550.618307565.77500-0.207903.117202.43110K562DDX47
RAC1ENSG00000136238.138153.520006483.703400.330505.930704.58000K562DKC1
RAC1ENSG00000136238.132834.563403747.50660-0.402804.465803.42340K562EIF4A3
RAC1ENSG00000136238.132632.914703374.85350-0.358205.045903.41730K562EIF4B
RAC1ENSG00000136238.133741.380807407.66420-0.9854014.3683012.33860K562FMR1
RAC1ENSG00000136238.135088.987206951.67720-0.450003.011102.18400K562GPKOW
RAC1ENSG00000136238.136196.023007219.25980-0.220502.102601.43760K562GRSF1
RAC1ENSG00000136238.133040.324504400.09430-0.533308.636207.63300K562HNRNPC
RAC1ENSG00000136238.138081.331206394.373000.337703.610502.65180K562KIF1C
RAC1ENSG00000136238.133738.617504588.43060-0.295502.775301.93420K562MAGOH
RAC1ENSG00000136238.137903.572106120.962400.368604.250102.83580K562MAK16
RAC1ENSG00000136238.133534.897905427.08840-0.6185017.5330015.74450K562MTPAP
RAC1ENSG00000136238.137726.157805020.957600.621706.038404.54510K562NAA15
RAC1ENSG00000136238.135252.250506030.32860-0.199302.837602.08270K562NSUN2
RAC1ENSG00000136238.134168.565903399.050300.294302.565401.84280K562PRPF8
RAC1ENSG00000136238.133115.399603945.10700-0.340603.616302.56390K562PSIP1
RAC1ENSG00000136238.1311613.390605975.502500.9586022.9977021.44910K562PUS1
RAC1ENSG00000136238.138702.366905822.172300.5798014.9929013.59940K562RBM15
RAC1ENSG00000136238.133799.189508098.59230-1.0920013.439909.92050K562SMN1
RAC1ENSG00000136238.135121.039806095.73470-0.251404.542803.37770K562SRPK2
RAC1ENSG00000136238.132969.404303640.29080-0.293903.008201.89880K562SRSF4
RAC1ENSG00000136238.134599.121903875.910500.246702.529001.76080K562U2AF2
RAC1ENSG00000136238.135077.377106394.05790-0.332605.507404.53350K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RAC1 is not available on ENCORE database.





8 RBPs can affect the splicing of RAC1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERAC1ENSG00000136238.13chr7+6438292643834964315546431672643975664398190.053000.000000.00000includedHepG2SRSF9
MXERAC1ENSG00000136238.13chr7+643975664398196441498644165864315546431672644194664421120.141000.003550.043021includedK562DROSHA
MXERAC1ENSG00000136238.13chr7+643975664398196441498644165864315546431672644194664421120.071000.004160.056681includedK562U2AF1
MXERAC1ENSG00000136238.13chr7+643975664398196441498644165864315546431672644194664421120.092000.000140.003351includedK562U2AF2
MXERAC1ENSG00000136238.13chr7+643975664398196441498644165864315546431672644194664421120.107000.000040.004081includedK562TAF15
MXERAC1ENSG00000136238.13chr7+64268426426914643155464316726414153641440164397566439819-0.118000.000000.001022includedK562CPSF6
MXERAC1ENSG00000136238.13chr7+642684264269146431554643167264141536414401643975664398190.115000.001180.034681includedK562PPIL4
MXERAC1ENSG00000136238.13chr7+643975664398196441498644165864315546431672644194664421120.141000.003530.051221includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RAC1 is not avaliable on ENCORE database.