OTUD6B

General Information

Gene Name       : OTUD6B
Gene ID             : ENSG00000155100.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: OTUD6B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878OTUD6BENSG00000155100.1021.2617.7219.49ENCSR000AEF
HepG2OTUD6BENSG00000155100.107.2910.358.82ENCSR985KAT
K562OTUD6BENSG00000155100.1027.3631.6329.49ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for OTUD6B is not avaliable on ENCORE database.



Proteins bound to RNA
  • OTUD6B RNA is bound by 14 proteins.  







eCLIP assay for OTUD6B is not avaliable on ENCORE database.





14 proteins are bound to OTUD6B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr89209289692092961+3'-UTR,CDS,intron-Proximal3.659553.27569HepG2BCLAF1
chr89209058792090623+3'-UTR,CDS3.819614.20387K562ZNF622
chr89209085092090893+3'-UTR,CDS4.652885.87202K562UCHL5
chr89209072192090846+3'-UTR,CDS3.889444.75336K562PUM1
chr89209074492090871+3'-UTR,CDS3.068984.24005HepG2BCLAF1
chr89209070592090778+3'-UTR,CDS3.813478.25234K562ZNF622
chr89209058992090687+3'-UTR,CDS4.704305.68196HepG2BCLAF1
chr89209076892090850+3'-UTR,CDS4.027177.79255K562UCHL5
chr89209760792097663+3'-UTR4.521605.20135HepG2QKI
chr89209060292090717+3'-UTR,CDS3.320827.34382K562UCHL5
chr89209078492090866+3'-UTR,CDS3.612694.22460K562RBM15
chr89209292192092981+3'-UTR,CDS,intron-Proximal4.063554.54206HepG2PRPF8
chr89209622192096285+3'-UTR,CDS,intron-Proximal3.247275.52172K562SF3B4
chr89209746692097539+3'-UTR4.105968.64567K562KHSRP
chr89208258592082702+5'-UTR,CDS,intron-Proximal4.417143.48757K562TRA2A
chr89208256192082620+5'-UTR,CDS4.624265.29868K562UCHL5
chr89208349292083570+5'-UTR,CDS,intron-Proximal4.319796.77156K562AQR
chr89208349192083564+5'-UTR,CDS,intron-Proximal3.580343.87469HepG2BCLAF1
chr89208607992086131+5'-UTR,CDS3.076134.00731K562UCHL5
chr89208336492083539+5'-UTR,CDS,intron-Proximal3.235375.78238HepG2PPIG
chr89208336892083531+5'-UTR,CDS,intron-Proximal4.7106523.61875K562UCHL5
chr89208336392083521+5'-UTR,CDS,intron-Proximal3.8424411.00784K562ZNF622
chr89208255992082700+5'-UTR,CDS,intron-Proximal4.3106511.38767K562ZNF622
chr89208345792083529+5'-UTR,CDS,intron-Proximal3.374765.02533K562GRWD1
chr89208336292083446+5'-UTR,CDS,intron-Proximal3.198834.02291HepG2GRWD1
chr89208600992086092+5'-UTR,CDS,intron-Proximal5.222914.90235K562SF3B4
chr89208350792083582+5'-UTR,CDS,intron-Proximal4.308433.85435K562PRPF8
chr89209299992093066+intron-Distal,intron-Proximal4.267203.85435K562PRPF8
chr89208497592085055+intron-Distal4.108826.86842HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for OTUD6B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for OTUD6B is not available on ENCORE database.

  • 92 RBPs can affect the levels of OTUD6B.  








The Knockdown/knockout RNA-Seq assay for OTUD6B is not available on ENCORE database.





92 RBPs can affect the gene expression of OTUD6B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
OTUD6BENSG00000155100.6145.74260255.22380-0.808302.301201.45030HepG2BCCIP
OTUD6BENSG00000155100.6201.49290370.53380-0.878901.986501.47180HepG2BOP1
OTUD6BENSG00000155100.6202.84920333.26120-0.716203.608402.47980HepG2CCAR1
OTUD6BENSG00000155100.679.90510340.19610-2.090005.510104.57040HepG2CPSF6
OTUD6BENSG00000155100.6126.64660217.06900-0.777302.338701.76700HepG2DDX6
OTUD6BENSG00000155100.6159.33330227.58310-0.514302.391501.75430HepG2DKC1
OTUD6BENSG00000155100.6122.79820178.19340-0.537202.209101.57350HepG2DNAJC21
OTUD6BENSG00000155100.6125.44500176.59560-0.493402.137801.55080HepG2DNAJC2
OTUD6BENSG00000155100.6100.48120208.77000-1.055003.343302.69590HepG2EIF2S1
OTUD6BENSG00000155100.6128.73240232.45630-0.852605.097603.96680HepG2EWSR1
OTUD6BENSG00000155100.6166.1805090.088800.883204.001203.06340HepG2FUBP3
OTUD6BENSG00000155100.682.72610179.90030-1.120805.579504.70600HepG2HNRNPA1
OTUD6BENSG00000155100.6123.68530200.09770-0.694002.866802.16230HepG2HNRNPC
OTUD6BENSG00000155100.6148.26640261.26220-0.817305.599404.62190HepG2HNRNPF
OTUD6BENSG00000155100.6178.97220287.95180-0.686105.224304.32290HepG2HNRNPL
OTUD6BENSG00000155100.6203.53100368.08360-0.854801.918601.38610HepG2HNRNPLL
OTUD6BENSG00000155100.6138.17330257.27010-0.896806.040205.01200HepG2IGF2BP1
OTUD6BENSG00000155100.6231.99470351.76710-0.600502.870602.02540HepG2LARP4
OTUD6BENSG00000155100.6140.76320234.09450-0.733802.274901.69900HepG2MATR3
OTUD6BENSG00000155100.6220.88190313.43640-0.504903.055402.25470HepG2NOL12
OTUD6BENSG00000155100.6241.02450181.187100.411601.870201.35430HepG2PCBP1
OTUD6BENSG00000155100.6216.60530299.19000-0.466002.331301.77770HepG2PUF60
OTUD6BENSG00000155100.6179.77900242.29050-0.430502.087901.53460HepG2PUS1
OTUD6BENSG00000155100.6392.02120208.452800.911104.514403.62560HepG2RAVER1
OTUD6BENSG00000155100.6252.76170326.39120-0.368801.905401.45420HepG2RBM22
OTUD6BENSG00000155100.6337.02050181.214300.895006.949905.92090HepG2RBM25
OTUD6BENSG00000155100.6162.75240281.42140-0.790104.858103.98620HepG2RPLP0
OTUD6BENSG00000155100.6152.38990364.37100-1.257603.013602.27870HepG2SF3B1
OTUD6BENSG00000155100.6286.62370191.945100.578403.301302.66190HepG2SF3B4
OTUD6BENSG00000155100.6466.02430368.648100.338102.286701.81720HepG2SRFBP1
OTUD6BENSG00000155100.6572.53020200.351401.5147022.2252021.16080HepG2SRSF1
OTUD6BENSG00000155100.6137.61710256.67640-0.899306.582505.58320HepG2SRSF7
OTUD6BENSG00000155100.6205.12390320.07600-0.641904.657904.02710HepG2SSB
OTUD6BENSG00000155100.6129.79220249.81940-0.944702.949602.25500HepG2SUPV3L1
OTUD6BENSG00000155100.6242.36730180.089900.428401.875301.39710HepG2TAF15
OTUD6BENSG00000155100.6240.00320165.471400.536402.631501.81500HepG2TIA1
OTUD6BENSG00000155100.674.07350193.17770-1.382907.987307.21800HepG2TIAL1
OTUD6BENSG00000155100.6125.38510194.87210-0.636203.281502.67910HepG2TRIM56
OTUD6BENSG00000155100.6107.03700245.91860-1.200104.024503.15840HepG2XRN2
OTUD6BENSG00000155100.6842.69760564.349600.578305.545503.80620K562AARS
OTUD6BENSG00000155100.6761.80700988.17960-0.375302.492901.56860K562AKAP8
OTUD6BENSG00000155100.6960.129301473.43400-0.617907.229606.35280K562AQR
OTUD6BENSG00000155100.6625.43460834.18290-0.415504.271303.06090K562BCLAF1
OTUD6BENSG00000155100.6560.324801046.47670-0.901204.080803.01910K562BOP1
OTUD6BENSG00000155100.6183.88220327.00300-0.830505.831404.15400K562CCAR1
OTUD6BENSG00000155100.6820.703301814.17600-1.144404.227002.86830K562CNOT7
OTUD6BENSG00000155100.6963.092201335.72270-0.471906.137904.45330K562CPEB4
OTUD6BENSG00000155100.6311.213601112.79840-1.838209.708008.22200K562CPSF6
OTUD6BENSG00000155100.6481.56730632.85190-0.394102.939801.85030K562CSTF2
OTUD6BENSG00000155100.6509.18940649.39540-0.350902.408401.43870K562DDX3X
OTUD6BENSG00000155100.61597.453501382.238000.208702.052501.47730K562DDX47
OTUD6BENSG00000155100.61264.574001006.958300.328503.440402.44960K562DKC1
OTUD6BENSG00000155100.6517.61410713.25050-0.462504.972403.32560K562EIF2S1
OTUD6BENSG00000155100.6887.309901194.47810-0.428903.154902.39370K562EIF2S2
OTUD6BENSG00000155100.6412.55290678.43760-0.717606.986505.68890K562EIF4A3
OTUD6BENSG00000155100.6483.99260610.95050-0.336102.477701.40420K562EIF4B
OTUD6BENSG00000155100.6799.639201116.94800-0.482102.945602.06990K562FIP1L1
OTUD6BENSG00000155100.6690.830501132.06510-0.712602.826601.96250K562FMR1
OTUD6BENSG00000155100.6514.42520656.45660-0.351702.707501.38540K562FUS
OTUD6BENSG00000155100.6962.66930705.543100.448204.938604.16350K562FXR1
OTUD6BENSG00000155100.61124.84100825.045900.447102.051501.45590K562G3BP2
OTUD6BENSG00000155100.6626.842001062.52330-0.761303.026702.19710K562GPKOW
OTUD6BENSG00000155100.61012.222001591.94200-0.653304.735503.74760K562GRSF1
OTUD6BENSG00000155100.6505.98650875.77220-0.791508.565306.77250K562HNRNPA1
OTUD6BENSG00000155100.6296.47630617.68140-1.0589012.9839011.76650K562HNRNPC
OTUD6BENSG00000155100.6296.92220551.51560-0.893308.977206.85250K562HNRNPF
OTUD6BENSG00000155100.6930.128401249.14180-0.425404.136102.81620K562HNRNPL
OTUD6BENSG00000155100.6569.52970925.26760-0.700102.711201.53400K562IGF2BP3
OTUD6BENSG00000155100.6536.91120907.06650-0.756502.787901.85100K562KRR1
OTUD6BENSG00000155100.6559.87270954.72520-0.770002.903101.95600K562MATR3
OTUD6BENSG00000155100.6535.016101037.10970-0.954903.840102.79580K562METAP2
OTUD6BENSG00000155100.6988.376601953.26390-0.9828015.4359012.98710K562MSI2
OTUD6BENSG00000155100.6702.63570922.86510-0.393304.293603.30490K562MTPAP
OTUD6BENSG00000155100.6517.59050677.48840-0.388402.923201.65930K562NCBP2
OTUD6BENSG00000155100.6725.427601025.32210-0.499207.983706.80840K562NSUN2
OTUD6BENSG00000155100.6474.13440724.08840-0.610904.700103.61720K562PCBP3
OTUD6BENSG00000155100.6426.00550555.40510-0.382702.492601.73440K562POLR2G
OTUD6BENSG00000155100.6789.522501267.83930-0.683304.811803.68440K562PPIG
OTUD6BENSG00000155100.6831.51890647.954600.359802.335701.64440K562PRPF8
OTUD6BENSG00000155100.6345.12710553.79530-0.682205.194203.90250K562PSIP1
OTUD6BENSG00000155100.61572.666801999.38050-0.346302.167201.44690K562PUF60
OTUD6BENSG00000155100.61502.323902083.71860-0.472004.760803.48980K562PUM2
OTUD6BENSG00000155100.61416.31940928.033500.609806.262105.48460K562PUS1
OTUD6BENSG00000155100.61091.57880904.212100.271602.188701.65090K562RBM15
OTUD6BENSG00000155100.6573.63880891.52650-0.636102.183101.44060K562RBM22
OTUD6BENSG00000155100.6506.53170838.57380-0.727305.845703.26200K562RECQL
OTUD6BENSG00000155100.6886.22650660.109000.424902.788301.96900K562RPS19
OTUD6BENSG00000155100.6639.58670494.864800.370002.391001.38850K562SAFB
OTUD6BENSG00000155100.6890.933301652.27220-0.891103.152301.51370K562SBDS
OTUD6BENSG00000155100.6557.973901010.22520-0.856403.696802.56520K562SF3B1
OTUD6BENSG00000155100.6256.31730360.21400-0.490902.745601.48490K562SLBP
OTUD6BENSG00000155100.6336.45760478.89460-0.509303.093101.99410K562SRFBP1
OTUD6BENSG00000155100.6829.393401036.64650-0.321803.129002.14050K562SRPK2
OTUD6BENSG00000155100.61315.56880910.898900.530203.318802.54860K562SRSF1
OTUD6BENSG00000155100.6327.24980490.70770-0.584502.288701.34760K562SRSF4
OTUD6BENSG00000155100.6601.95860765.94310-0.347603.017201.67120K562SSB
OTUD6BENSG00000155100.6903.259701340.58230-0.569603.566102.11170K562STAU1
OTUD6BENSG00000155100.6867.785301616.97730-0.897903.026201.31060K562STIP1
OTUD6BENSG00000155100.6367.75280627.52870-0.770906.101204.54760K562SUPV3L1
OTUD6BENSG00000155100.6884.75140557.079400.667308.425806.98880K562SYNCRIP
OTUD6BENSG00000155100.6550.58690922.09590-0.743902.726202.02320K562TARDBP
OTUD6BENSG00000155100.6232.87560532.67060-1.1937012.5238010.43170K562TIAL1
OTUD6BENSG00000155100.6368.92660565.78190-0.616904.948503.59610K562TRIM56
OTUD6BENSG00000155100.6845.544501307.04950-0.628403.313501.76900K562TRIP6
OTUD6BENSG00000155100.6818.758101019.36070-0.316203.111201.76220K562TROVE2
OTUD6BENSG00000155100.61715.503102253.89060-0.393802.703101.31920K562UBE2L3
OTUD6BENSG00000155100.6342.56580664.07750-0.955009.719807.75880K562UCHL5
OTUD6BENSG00000155100.6607.186001087.17580-0.8404015.4024013.86910K562UPF1
OTUD6BENSG00000155100.6578.383901033.04770-0.836808.787606.75850K562UTP3
OTUD6BENSG00000155100.6653.37890930.25380-0.509705.037503.84090K562WDR3
OTUD6BENSG00000155100.61209.930501745.53470-0.528706.900104.86300K562WRN
OTUD6BENSG00000155100.6996.592001659.97710-0.7361011.197809.32960K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for OTUD6B is not available on ENCORE database.





17 RBPs can affect the splicing of OTUD6B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEOTUD6BENSG00000155100.6chr8+920888199208895992086058920861399209058392090896-0.089000.000950.02012excludedK562SRSF1
SEOTUD6BENSG00000155100.6chr8+9208881992088959920860589208613992090583920908960.088000.000000.00502includedK562TROVE2
SEOTUD6BENSG00000155100.6chr8+9208881992088959920860589208613992090583920908960.208000.003190.06794includedHepG2HNRNPK
SEOTUD6BENSG00000155100.6chr8+9208881992088959920860589208613992090583920908960.085000.005560.05069includedK562AQR
SEOTUD6BENSG00000155100.6chr8+920888199208895992086058920861399209058392090896-0.093000.000020.00194excludedK562FXR1
SEOTUD6BENSG00000155100.6chr8+920860589208613992083365920835179209058392090896-0.110000.000000.00000excludedK562PUS1
SEOTUD6BENSG00000155100.6chr8+9208881992088959920860589208613992090583920908960.082000.000030.01165includedK562MTPAP
SEOTUD6BENSG00000155100.6chr8+9208881992088959920860589208613992090583920908960.300000.000120.01205includedHepG2NCBP2
SEOTUD6BENSG00000155100.6chr8+9208881992088959920860589208613992090583920908960.471000.000090.00768includedHepG2PTBP1
SEOTUD6BENSG00000155100.6chr8+9208881992088959920860589208613992090583920908960.342000.000130.00868includedHepG2MATR3
SEOTUD6BENSG00000155100.6chr8+9208881992088959920860589208613992090583920908960.097000.000040.04420includedK562DDX21
SEOTUD6BENSG00000155100.6chr8+920888199208895992086058920861399209058392090896-0.170000.000100.03260excludedK562FXR2
SEOTUD6BENSG00000155100.6chr8+9208881992088959920860589208613992090583920908960.055000.000220.02327includedK562HNRNPUL1
SEOTUD6BENSG00000155100.6chr8+9208881992088959920860589208613992090583920908960.083000.000650.08990includedK562SRSF7
SEOTUD6BENSG00000155100.6chr8+9208881992088959920860589208613992090583920908960.186000.000000.00000includedK562CPSF6
SEOTUD6BENSG00000155100.6chr8+920888199208895992086058920861399209058392090896-0.078000.000040.04345excludedK562AARS
SEOTUD6BENSG00000155100.6chr8+9208606292086139920833659208351792090583920908960.061000.000750.09868includedK562NPM1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for OTUD6B is not avaliable on ENCORE database.