OCRL

General Information

Gene Name       : OCRL
Gene ID             : ENSG00000122126.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: OCRL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878OCRLENSG00000122126.163.402.833.12ENCSR000AEF
HepG2OCRLENSG00000122126.1611.4316.4813.96ENCSR985KAT
K562OCRLENSG00000122126.1610.8310.7910.81ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for OCRL is not avaliable on ENCORE database.



Proteins bound to RNA
  • OCRL RNA is bound by 15 proteins.  







eCLIP assay for OCRL is not avaliable on ENCORE database.





15 proteins are bound to OCRL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX128725766128725813+3'-UTR4.016163.20319K562UPF1
chrX128674350128674454+5'-UTR,CDS,intron-Distal3.163693.78281HepG2SRSF1
chrX128701319128701399+CDS,intron-Proximal3.050724.07440K562PRPF8
chrX128696741128696760+CDS3.909843.04254K562UCHL5
chrX128674693128674725+CDS,intron-Distal,intron-Proximal3.123636.02419K562AQR
chrX128691269128691378+CDS,intron-Proximal4.172065.97994K562AQR
chrX128696417128696479+CDS,intron-Proximal3.480336.74947HepG2BCLAF1
chrX128709875128709935+CDS4.644365.44793K562ZNF622
chrX128674651128674816+CDS,intron-Distal,intron-Proximal3.769515.00154HepG2AQR
chrX128709200128709223+CDS3.526883.87469HepG2BCLAF1
chrX128701319128701378+CDS,intron-Proximal4.455284.16174HepG2PRPF8
chrX128692658128692729+CDS3.411827.43909HepG2BCLAF1
chrX128674725128674772+CDS,intron-Distal3.392345.81258K562AQR
chrX128710323128710385+CDS4.187823.80193HepG2GRWD1
chrX128709168128709230+CDS,intron-Proximal4.284404.50960HepG2GRWD1
chrX128694529128694623+CDS4.308005.23082K562DDX24
chrX128691301128691417+CDS,intron-Proximal3.357367.87154HepG2PPIG
chrX128694533128694623+CDS3.845844.24220K562ZNF622
chrX128694527128694629+CDS,intron-Proximal3.037005.93573HepG2BCLAF1
chrX128710327128710363+CDS4.480334.37348HepG2BCLAF1
chrX128722380128722440+intron-Distal3.513155.76944HepG2U2AF2
chrX128687277128687286+intron-Distal4.667364.98250K562AQR
chrX128674506128674562+intron-Distal,intron-Proximal4.252973.86417HepG2PRPF4
chrX128715779128715863+intron-Distal3.945259.01453K562PTBP1
chrX128688341128688408+intron-Distal3.926426.80869K562AQR
chrX128715863128715904+intron-Distal4.415286.11515K562PTBP1
chrX128674641128674717+intron-Distal,intron-Proximal4.419623.85435K562PRPF8
chrX128676285128676363+intron-Distal4.923816.58335HepG2QKI
chrX128714726128714791+intron-Distal4.452554.85866HepG2QKI
chrX128674811128674883+intron-Distal,intron-Proximal3.721834.49024K562AQR
chrX128687345128687394+intron-Distal4.116076.01372K562AQR
chrX128687286128687344+intron-Distal4.299478.13013K562AQR
chrX128676445128676548+intron-Distal5.713778.32953HepG2QKI
chrX128687149128687308+intron-Distal3.963303.32022K562UCHL5
chrX128715784128715929+intron-Distal4.032099.81671HepG2PTBP1
chrX128674630128674694+intron-Distal,intron-Proximal5.763438.14804HepG2EFTUD2
chrX128688335128688418+intron-Distal4.624755.25202HepG2AQR
chrX128687271128687359+intron-Distal4.564384.58968K562PRPF8
chrX128676291128676357+intron-Distal5.763009.13109K562QKI
chrX128676426128676533+intron-Distal5.6126917.81457K562QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for OCRL is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for OCRL is not available on ENCORE database.

  • 103 RBPs can affect the levels of OCRL.  








The Knockdown/knockout RNA-Seq assay for OCRL is not available on ENCORE database.





103 RBPs can affect the gene expression of OCRL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
OCRLENSG00000122126.111305.689501612.54110-0.304504.160503.44330HepG2ACO1
OCRLENSG00000122126.111425.169002282.99720-0.679806.809606.01700HepG2AKAP1
OCRLENSG00000122126.111413.262701889.01100-0.418603.380602.51300HepG2ASCC1
OCRLENSG00000122126.111559.009002099.69390-0.429507.481006.44220HepG2AUH
OCRLENSG00000122126.11859.461301223.55480-0.509603.204202.19570HepG2BCCIP
OCRLENSG00000122126.112329.230701066.906201.1263025.0446023.53860HepG2BOP1
OCRLENSG00000122126.111388.661801794.68320-0.370002.808602.03030HepG2CIRBP
OCRLENSG00000122126.11856.692501895.03150-1.1454011.6657010.13380HepG2CNOT7
OCRLENSG00000122126.11646.02120979.46620-0.600405.799404.83760HepG2CPSF6
OCRLENSG00000122126.111259.263401796.22910-0.512408.584907.57260HepG2CELF1
OCRLENSG00000122126.112415.484401931.243700.322706.414705.35300HepG2DAZAP1
OCRLENSG00000122126.111499.518101125.685700.413602.937401.61080HepG2DDX27
OCRLENSG00000122126.111373.385301878.55330-0.451903.340302.66850HepG2DDX6
OCRLENSG00000122126.111642.037601279.582400.359704.472503.59490HepG2DNAJC21
OCRLENSG00000122126.11986.688501268.41230-0.362405.329504.46810HepG2DNAJC2
OCRLENSG00000122126.111050.205701410.74580-0.425803.284402.28750HepG2EEF2
OCRLENSG00000122126.111386.978601995.90980-0.525104.343303.54610HepG2EIF4A3
OCRLENSG00000122126.111631.091202410.77280-0.5637012.8041011.66760HepG2ETF1
OCRLENSG00000122126.11741.447201023.51920-0.465104.869903.28010HepG2FAM120A
OCRLENSG00000122126.111551.03610981.169500.660602.589301.60880HepG2FTO
OCRLENSG00000122126.111411.151801868.01860-0.404602.952102.26650HepG2G3BP1
OCRLENSG00000122126.11838.264801110.26890-0.405402.632602.00550HepG2GPKOW
OCRLENSG00000122126.111044.565301754.29400-0.748006.097504.44210HepG2GRSF1
OCRLENSG00000122126.111163.616201602.68780-0.461902.821801.43380HepG2HNRNPA0
OCRLENSG00000122126.111462.031601891.33520-0.371403.110102.37060HepG2HNRNPK
OCRLENSG00000122126.111402.680901759.17170-0.326705.068204.17840HepG2HNRNPL
OCRLENSG00000122126.111724.240501059.553000.702408.552707.51180HepG2HNRNPLL
OCRLENSG00000122126.111137.265401427.47520-0.327904.168203.43620HepG2HNRNPU
OCRLENSG00000122126.111116.719801458.11140-0.384806.274305.21350HepG2ILF2
OCRLENSG00000122126.111620.658902309.32750-0.510903.372601.99120HepG2KRR1
OCRLENSG00000122126.111099.220401398.05090-0.346902.501901.42640HepG2LARP7
OCRLENSG00000122126.111147.888601468.29120-0.355202.499901.35190HepG2LIN28B
OCRLENSG00000122126.111629.172302025.62720-0.314201.899601.37150HepG2MATR3
OCRLENSG00000122126.111595.144301080.677000.561703.409202.32500HepG2MTPAP
OCRLENSG00000122126.111630.318001230.261000.406104.129402.64910HepG2NAA15
OCRLENSG00000122126.111628.233902073.36400-0.348702.405401.81220HepG2NCBP2
OCRLENSG00000122126.111213.040001915.02500-0.6587012.1154010.56660HepG2NOL12
OCRLENSG00000122126.111452.92830939.519800.628907.265206.08920HepG2NSUN2
OCRLENSG00000122126.111126.754501412.90250-0.326503.372502.44620HepG2PARN
OCRLENSG00000122126.111615.572801890.69750-0.226902.524301.93760HepG2PCBP1
OCRLENSG00000122126.111702.630701440.657000.240902.597301.84630HepG2PRPF4
OCRLENSG00000122126.111615.554501923.85150-0.252003.039002.47120HepG2PTBP1
OCRLENSG00000122126.11918.799801940.65400-1.0787046.6585044.83500HepG2PUM1
OCRLENSG00000122126.111957.732401642.453100.253203.307002.64880HepG2PUS1
OCRLENSG00000122126.112866.171202083.587100.460007.395506.44720HepG2QKI
OCRLENSG00000122126.11858.821101541.48960-0.843903.383202.60520HepG2RAVER1
OCRLENSG00000122126.111666.075702014.95100-0.274303.111702.57050HepG2RBM22
OCRLENSG00000122126.111263.802001685.77890-0.415603.115802.05980HepG2RBM27
OCRLENSG00000122126.111745.817801994.10540-0.191801.929601.40190HepG2RECQL
OCRLENSG00000122126.11767.959101114.34530-0.537105.800104.94860HepG2RPS19
OCRLENSG00000122126.111428.228901903.13700-0.414202.469401.71220HepG2RPS3A
OCRLENSG00000122126.11647.25640918.22780-0.504503.083402.26010HepG2RRP9
OCRLENSG00000122126.111520.745301271.204600.258503.151102.47280HepG2SAFB2
OCRLENSG00000122126.111726.949501048.729500.719509.961708.69470HepG2SF3B1
OCRLENSG00000122126.111187.021201482.39680-0.320604.787403.97880HepG2SMN1
OCRLENSG00000122126.111954.675802275.79700-0.219402.737002.23700HepG2SRFBP1
OCRLENSG00000122126.11774.648601128.48960-0.542803.564202.41540HepG2SRSF3
OCRLENSG00000122126.111403.534201805.03690-0.363005.189704.37390HepG2SRSF5
OCRLENSG00000122126.112004.394301700.876700.236802.896202.33450HepG2SRSF9
OCRLENSG00000122126.111691.553701975.90280-0.224202.590902.08910HepG2SSB
OCRLENSG00000122126.111178.524601655.60150-0.490403.370002.14150HepG2STIP1
OCRLENSG00000122126.111495.266801222.400400.290602.419801.53710HepG2SUPT6H
OCRLENSG00000122126.112407.363101879.176400.357304.884004.17200HepG2TAF15
OCRLENSG00000122126.112049.832701726.715500.247402.115101.38220HepG2TIA1
OCRLENSG00000122126.111000.505701399.46860-0.484107.984107.10450HepG2TRIM56
OCRLENSG00000122126.11914.452901548.55290-0.759909.403908.23370HepG2U2AF1
OCRLENSG00000122126.11523.21580707.50600-0.435302.589701.85610HepG2UCHL5
OCRLENSG00000122126.112066.169501798.600500.200002.206201.57150HepG2UPF1
OCRLENSG00000122126.111439.456901736.47430-0.270603.383402.73270HepG2UTP3
OCRLENSG00000122126.11849.883501178.90520-0.472103.193902.41730HepG2XRN2
OCRLENSG00000122126.111009.987601539.38750-0.608002.540001.30300HepG2ZRANB2
OCRLENSG00000122126.112398.916701551.032200.6291016.1622014.90820K562AGGF1
OCRLENSG00000122126.112254.732701704.356900.403604.198202.93070K562AKAP8
OCRLENSG00000122126.111659.14950894.330200.8915013.1418011.18350K562BOP1
OCRLENSG00000122126.112275.944401853.563000.296103.098301.83960K562CCDC124
OCRLENSG00000122126.111197.349701501.41490-0.326503.565302.30230K562CPEB4
OCRLENSG00000122126.113158.065402517.578700.326903.734602.59500K562CELF1
OCRLENSG00000122126.111392.91760908.214800.616908.532406.61490K562DDX3X
OCRLENSG00000122126.111835.248601553.514500.240302.575001.94360K562DDX47
OCRLENSG00000122126.11783.277001009.82050-0.366503.717802.90610K562EIF2S2
OCRLENSG00000122126.111078.86360854.507900.336203.301902.01610K562EIF4B
OCRLENSG00000122126.111361.82830967.572700.493004.696803.58010K562FMR1
OCRLENSG00000122126.111259.46880820.127500.618803.240102.24510K562FTO
OCRLENSG00000122126.111074.01690826.992200.377003.711702.12130K562FUS
OCRLENSG00000122126.111345.628701042.500100.368103.260801.67870K562G3BP1
OCRLENSG00000122126.111376.980901053.328300.386502.172701.55650K562G3BP2
OCRLENSG00000122126.111041.249801345.68960-0.370003.286402.46530K562GRSF1
OCRLENSG00000122126.111479.861501077.269800.458005.172103.71830K562HNRNPA1
OCRLENSG00000122126.111833.338701097.762300.739802.943301.67730K562HNRNPA2B1
OCRLENSG00000122126.111543.398001090.298400.501303.858402.56590K562IGF2BP2
OCRLENSG00000122126.112146.518001712.767600.325603.038502.17060K562KIF1C
OCRLENSG00000122126.111100.78240839.318300.391103.176501.66480K562LARP7
OCRLENSG00000122126.111225.50790886.178800.467602.929702.02680K562METAP2
OCRLENSG00000122126.111243.17550947.492500.391703.924302.44000K562NCBP2
OCRLENSG00000122126.111452.449501213.781400.258903.415202.59490K562NSUN2
OCRLENSG00000122126.111612.245901147.313900.490702.444701.30330K562PABPC1
OCRLENSG00000122126.111971.266702376.18360-0.269502.672601.62700K562PUM1
OCRLENSG00000122126.113017.330801600.554700.9146017.0177015.71210K562PUS1
OCRLENSG00000122126.112019.888201559.509500.373104.835104.07130K562RBM15
OCRLENSG00000122126.111753.229301276.140200.458105.204303.01940K562RBM17
OCRLENSG00000122126.111300.06360998.950100.380003.454001.94940K562RBM25
OCRLENSG00000122126.111038.219201357.37710-0.386702.671001.68730K562RPS3
OCRLENSG00000122126.111455.79790877.455900.730302.650501.48460K562SF1
OCRLENSG00000122126.111724.552201197.695900.525909.055407.64230K562SF3A3
OCRLENSG00000122126.111150.38250863.481800.413802.773201.79810K562SF3B1
OCRLENSG00000122126.111430.208701095.146800.385004.161203.10710K562SF3B4
OCRLENSG00000122126.111946.536801069.321600.864103.885402.23380K562SFPQ
OCRLENSG00000122126.111594.497801227.065600.377806.073904.75080K562SRPK2
OCRLENSG00000122126.111412.309901091.478900.371703.613702.81350K562SRSF1
OCRLENSG00000122126.111020.826001310.41830-0.360303.106601.97440K562SRSF4
OCRLENSG00000122126.112149.757701205.586500.834303.763701.99300K562SUPT6H
OCRLENSG00000122126.111545.984301033.955200.580302.837001.35490K562TAF15
OCRLENSG00000122126.111470.110701097.821200.421203.877601.96770K562TBRG4
OCRLENSG00000122126.111435.505701020.872000.491703.677902.37760K562U2AF1
OCRLENSG00000122126.111818.261601054.386100.7861015.6845013.74550K562U2AF2
OCRLENSG00000122126.111579.701001286.998400.295503.609502.79700K562UPF1
OCRLENSG00000122126.111485.836401101.243600.432004.620403.47390K562WDR3
OCRLENSG00000122126.112488.571601854.159100.424504.766903.58750K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for OCRL is not available on ENCORE database.





17 RBPs can affect the splicing of OCRL :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEOCRLENSG00000122126.11chrX+1287183201287183441287102931287105291287209781287210950.465000.000000.00000includedK562SRSF1
SEOCRLENSG00000122126.11chrX+1286918371286919271286913011286914121286926091286927300.122000.000190.04283includedK562FTO
SEOCRLENSG00000122126.11chrX+128691837128691927128691301128691412128692609128692730-0.158000.006830.09369excludedK562SF3B4
SEOCRLENSG00000122126.11chrX+1287183201287183441287102931287105291287209781287210950.406000.000010.00022includedHepG2U2AF1
SEOCRLENSG00000122126.11chrX+128691837128691927128691301128691412128692609128692730-0.338000.000000.00000excludedHepG2U2AF1
SEOCRLENSG00000122126.11chrX+128691837128691927128691301128691412128692609128692730-0.054000.003430.07943excludedK562AKAP8L
SEOCRLENSG00000122126.11chrX+1287183201287183441287102931287105291287209781287210950.214000.000000.00003includedHepG2QKI
SEOCRLENSG00000122126.11chrX+128691837128691927128691301128691412128692609128692730-0.315000.000120.00223excludedHepG2U2AF2
SEOCRLENSG00000122126.11chrX+1287183201287183441287102931287105291287209781287210950.208000.000240.01239includedK562FXR1
SEOCRLENSG00000122126.11chrX+128691837128691927128691301128691412128692609128692730-0.074000.000120.00284excludedK562PUS1
SEOCRLENSG00000122126.11chrX+1287183201287183441287102931287105291287209781287210950.192000.000010.00067includedHepG2PTBP1
SEOCRLENSG00000122126.11chrX+1287183201287183441287102931287105291287209781287210950.225000.000050.00192includedK562U2AF1
SEOCRLENSG00000122126.11chrX+128691837128691927128691301128691412128692609128692730-0.220000.000310.00872excludedK562U2AF1
SEOCRLENSG00000122126.11chrX+1287232131287233411287228621287229901287238211287239330.076000.001390.08437includedHepG2HNRNPL
SEOCRLENSG00000122126.11chrX+1287183201287183441287102931287105291287209781287210950.509000.000000.00000includedHepG2SRSF1
SEOCRLENSG00000122126.11chrX+128691837128691927128691301128691412128692609128692730-0.168000.000240.00973excludedHepG2SF3A3
SEOCRLENSG00000122126.11chrX+128691837128691927128691301128691412128692609128692730-0.073000.000310.01378excludedK562UTP18
SEOCRLENSG00000122126.11chrX+1287183201287183441287102931287105291287209781287210950.126000.000360.04335includedHepG2TAF15
SEOCRLENSG00000122126.11chrX+128691837128691927128691301128691412128692609128692730-0.173000.002550.04247excludedK562U2AF2
SEOCRLENSG00000122126.11chrX+128691837128691927128691301128691412128692609128692730-0.101000.000020.00099excludedK562RBM15
SEOCRLENSG00000122126.11chrX+128691837128691927128691301128691412128692609128692730-0.128000.000000.00005excludedK562AGGF1
SEOCRLENSG00000122126.11chrX+1287183201287183441287102931287105291287209781287210950.314000.000970.03942includedK562PTBP1
A3SSOCRLENSG00000122126.11chrX+1287098391287100391287098731287100391287091161287092270.083000.000790.00566longerK562AQR
A5SSOCRLENSG00000122126.11chrX+128709873128710039128709873128709942128710293128710529-0.065000.000780.01505shorterK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for OCRL is not avaliable on ENCORE database.