NGEF

General Information

Gene Name       : NGEF
Gene ID             : ENSG00000066248.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NGEF)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NGEFENSG00000066248.140.000.000.00ENCSR000AEF
HepG2NGEFENSG00000066248.1413.427.3110.37ENCSR985KAT
K562NGEFENSG00000066248.140.000.050.03ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NGEF is not avaliable on ENCORE database.



Proteins bound to RNA
  • NGEF RNA is bound by 18 proteins.  







eCLIP assay for NGEF is not avaliable on ENCORE database.





18 proteins are bound to NGEF RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2233743563233743683-3'-UTR,intron-Distal3.153143.27723HepG2AKAP1
chr2233743854233743966-3'-UTR,intron-Distal,intron-Proximal3.644973.73678HepG2UPF1
chr2233743568233743734-3'-UTR,intron-Distal4.288998.55060HepG2UPF1
chr2233877880233877941-5'-UTR,intron-Distal3.148964.14922HepG2NCBP2
chr2233877776233877864-5'-UTR,intron-Distal3.679906.53496HepG2SRSF1
chr2233749946233750028-CDS,intron-Distal,intron-Proximal3.068773.52281HepG2GRWD1
chr2233785059233785137-CDS,intron-Distal3.326244.41784HepG2GRWD1
chr2233749941233749999-CDS,intron-Distal,intron-Proximal3.560765.62957HepG2BUD13
chr2233748096233748159-CDS,intron-Distal3.942156.08299HepG2PPIG
chr2233747988233748035-CDS,intron-Distal,intron-Proximal4.196474.75655HepG2PRPF8
chr2233757534233757629-CDS,intron-Distal,intron-Proximal3.610099.09021HepG2PRPF8
chr2233785068233785191-CDS,intron-Distal3.431555.91405HepG2BCLAF1
chr2233749952233750022-CDS,intron-Distal,intron-Proximal4.215895.80295HepG2PPIG
chr2233749930233749999-CDS,intron-Distal,intron-Proximal4.5359812.15723HepG2PRPF8
chr2233757608233757683-CDS,intron-Distal3.369455.39266HepG2GRWD1
chr2233756014233756113-CDS,intron-Distal,intron-Proximal4.3253512.18707HepG2PRPF8
chr2233839544233839587-CDS,intron-Distal,intron-Proximal3.915513.38114HepG2GRWD1
chr2233763761233763945-intron-Distal4.183899.12433HepG2AGGF1
chr2233763328233763375-intron-Distal4.509715.71957HepG2AGGF1
chr2233750703233750775-intron-Distal5.450837.29411HepG2XPO5
chr2233783751233783795-intron-Distal3.419643.90822HepG2HNRNPM
chr2233750694233750785-intron-Distal5.021255.48368HepG2AGGF1
chr2233749069233749135-intron-Distal3.0960012.00556HepG2HNRNPL
chr2233763656233763725-intron-Distal3.160784.95192HepG2AGGF1
chr2233763472233763622-intron-Distal5.641549.05409HepG2XPO5
chr2233765945233766052-intron-Distal4.567804.26705HepG2AGGF1
chr2233761675233761754-intron-Distal5.314927.34252HepG2PCBP2
chr2233751005233751117-intron-Distal3.936977.41200HepG2HNRNPL
chr2233763570233763675-intron-Distal4.4987812.08200HepG2HNRNPL
chr2233750801233750839-intron-Distal4.677083.70058HepG2XPO5
chr2233876720233876795-intron-Distal4.125823.09122HepG2PTBP1
chr2233763917233763957-intron-Distal3.470163.76460HepG2HNRNPL
chr2233762199233762269-intron-Distal3.359024.35339HepG2CSTF2T
chr2233868923233869023-intron-Distal3.962687.29513HepG2PRPF4
chr2233812802233812903-intron-Distal4.087957.39509HepG2HNRNPL
chr2233852676233852740-intron-Distal3.858963.27714HepG2HNRNPL
chr2233750792233750917-intron-Distal4.6066713.70683HepG2HNRNPL
chr2233764178233764237-intron-Distal5.104097.65506HepG2AGGF1
chr2233761543233761675-intron-Distal5.9434811.78180HepG2PCBP2
chr2233763467233763570-intron-Distal4.2760012.68099HepG2HNRNPL
chr2233763524233763586-intron-Distal4.006663.57264HepG2GTF2F1
chr2233763478233763550-intron-Distal4.152778.36566HepG2AGGF1
chr2233761656233761760-intron-Distal3.641623.04847HepG2CSTF2T
chr2233750792233750889-intron-Distal5.8300813.63189HepG2AGGF1
chr2233749187233749265-intron-Distal3.7722011.46420HepG2HNRNPL
chr2233763550233763656-intron-Distal4.4956111.60247HepG2AGGF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NGEF is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NGEF is not available on ENCORE database.

  • 87 RBPs can affect the levels of NGEF.  








The Knockdown/knockout RNA-Seq assay for NGEF is not available on ENCORE database.





87 RBPs can affect the gene expression of NGEF :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NGEFENSG00000066248.10378.93540502.21490-0.406402.278401.30380HepG2AATF
NGEFENSG00000066248.10379.45220687.61290-0.8577014.3741013.21980HepG2ACO1
NGEFENSG00000066248.10325.862601293.79870-1.9893038.5032036.83840HepG2AKAP1
NGEFENSG00000066248.10634.16910949.86320-0.582903.751502.54750HepG2AKAP8
NGEFENSG00000066248.10473.53270690.76170-0.544706.253705.14390HepG2AKAP8L
NGEFENSG00000066248.10979.62740746.490800.392002.771701.36490HepG2ATP5C1
NGEFENSG00000066248.101375.72010687.365101.0009031.8540030.15380HepG2CKAP4
NGEFENSG00000066248.10201.60080497.44340-1.3030010.078208.65280HepG2CNOT7
NGEFENSG00000066248.10582.24610425.817200.451303.716402.53540HepG2YBX3
NGEFENSG00000066248.10526.82180697.00490-0.403902.118101.54360HepG2CELF1
NGEFENSG00000066248.101341.87680749.357700.8404024.0494022.26380HepG2DAZAP1
NGEFENSG00000066248.10848.65810635.898200.416305.250504.15060HepG2DDX19B
NGEFENSG00000066248.101000.73420651.516700.619106.219204.76250HepG2DDX5
NGEFENSG00000066248.10660.546201064.72340-0.688705.864704.99530HepG2DDX6
NGEFENSG00000066248.10936.23400657.833800.509006.465605.51290HepG2DKC1
NGEFENSG00000066248.10328.80810418.11780-0.346702.007001.39810HepG2DNAJC21
NGEFENSG00000066248.10845.55220414.429801.0287024.5533022.79030HepG2DNAJC2
NGEFENSG00000066248.10740.61590532.209600.476603.326702.10610HepG2EFTUD2
NGEFENSG00000066248.10356.36610518.26640-0.540303.233102.26120HepG2EIF3D
NGEFENSG00000066248.101129.71270708.252900.673507.846906.50580HepG2EIF4G2
NGEFENSG00000066248.101406.701501206.101400.221901.945401.42160HepG2ETF1
NGEFENSG00000066248.10465.47310671.83330-0.529404.641603.56480HepG2EWSR1
NGEFENSG00000066248.10260.29470835.39740-1.6823023.7323021.89070HepG2FIP1L1
NGEFENSG00000066248.101563.19220844.038000.8890015.4083013.62130HepG2FUBP3
NGEFENSG00000066248.10397.04990627.48400-0.660304.003302.66580HepG2FUS
NGEFENSG00000066248.10790.210201141.25100-0.530304.361503.50680HepG2FXR1
NGEFENSG00000066248.10702.020301058.57360-0.592504.964204.08430HepG2G3BP1
NGEFENSG00000066248.101464.276501123.947500.381502.814501.91530HepG2G3BP2
NGEFENSG00000066248.10738.71600512.404900.527602.894202.24080HepG2GPKOW
NGEFENSG00000066248.10615.99160422.123500.545104.159903.38980HepG2HNRNPA1
NGEFENSG00000066248.10897.07820597.345900.586607.762706.64100HepG2HNRNPF
NGEFENSG00000066248.101286.34820489.004701.3953025.6055024.00960HepG2HNRNPLL
NGEFENSG00000066248.10638.64770466.431300.453303.783203.08540HepG2HNRNPU
NGEFENSG00000066248.10738.282101033.89710-0.485803.129701.81170HepG2HSPD1
NGEFENSG00000066248.10985.27100588.208700.744109.999608.70590HepG2IGF2BP1
NGEFENSG00000066248.10433.262101009.90970-1.220905.729904.34050HepG2IGF2BP3
NGEFENSG00000066248.10612.28180476.443900.361802.800402.06420HepG2ILF2
NGEFENSG00000066248.10872.78540628.503200.473606.587705.05050HepG2KIF1C
NGEFENSG00000066248.10562.329401148.00780-1.0296012.3681011.10160HepG2MATR3
NGEFENSG00000066248.10303.18920542.38900-0.839104.420803.10770HepG2METAP2
NGEFENSG00000066248.10494.79260676.05010-0.450303.384702.49350HepG2MSI2
NGEFENSG00000066248.10840.10420498.896800.751704.751603.46250HepG2MTPAP
NGEFENSG00000066248.10925.432201175.02370-0.344502.123801.56570HepG2NCBP2
NGEFENSG00000066248.10671.26600433.654500.630204.189903.27460HepG2NSUN2
NGEFENSG00000066248.10359.65040461.68550-0.360302.363201.57480HepG2PARN
NGEFENSG00000066248.10829.59980593.972800.481902.501401.51410HepG2PCBP2
NGEFENSG00000066248.10904.15390653.858800.467503.590001.61600HepG2PES1
NGEFENSG00000066248.10575.29000416.019200.467504.064603.18870HepG2PPIL4
NGEFENSG00000066248.10415.94590624.38210-0.586003.079101.80390HepG2PRPF6
NGEFENSG00000066248.10740.55300325.273201.186907.315006.07690HepG2PRPF8
NGEFENSG00000066248.10830.033201093.01280-0.397104.896604.21220HepG2PTBP1
NGEFENSG00000066248.101111.21310709.348000.647506.785005.90650HepG2PUF60
NGEFENSG00000066248.10586.90470753.03470-0.359603.396102.75280HepG2PUM1
NGEFENSG00000066248.10384.67090752.46570-0.9680013.7233012.29930HepG2PUM2
NGEFENSG00000066248.101119.76430906.835400.304202.608401.77320HepG2RBM15
NGEFENSG00000066248.10291.820301008.06640-1.7884050.8880049.20810HepG2RBM22
NGEFENSG00000066248.10773.888301074.33890-0.473304.682403.82630HepG2RBM25
NGEFENSG00000066248.10695.120701216.41890-0.8073016.1732015.07300HepG2NELFE
NGEFENSG00000066248.10809.537301132.92790-0.484906.522405.63370HepG2RECQL
NGEFENSG00000066248.101099.37580563.136500.965008.349506.78330HepG2RPS10
NGEFENSG00000066248.10943.97080499.854500.917108.290606.92970HepG2RPS3A
NGEFENSG00000066248.10628.81980321.722300.966704.016103.09020HepG2RRP9
NGEFENSG00000066248.10744.63940415.376900.8420014.6912013.38300HepG2SAFB2
NGEFENSG00000066248.10737.49550474.644400.635703.491501.74920HepG2SBDS
NGEFENSG00000066248.10458.71510856.10360-0.900207.985006.79810HepG2SF3A3
NGEFENSG00000066248.10895.43400483.971800.887609.966108.69880HepG2SF3B1
NGEFENSG00000066248.10191.71600545.77580-1.509305.167803.08500HepG2SFPQ
NGEFENSG00000066248.101129.75820680.216600.7318016.5778015.12400HepG2SLBP
NGEFENSG00000066248.10801.03560558.204000.521003.160101.45450HepG2SND1
NGEFENSG00000066248.10184.55800538.52010-1.544903.879902.94600HepG2SNRNP70
NGEFENSG00000066248.10524.512701138.55410-1.1182030.7946029.59310HepG2SRFBP1
NGEFENSG00000066248.10472.894101187.79240-1.3287038.8966037.57260HepG2SRSF1
NGEFENSG00000066248.10889.60470700.414300.344903.601802.90470HepG2SRSF5
NGEFENSG00000066248.10831.85150586.895100.503105.649504.71250HepG2SRSF7
NGEFENSG00000066248.10487.55500966.33200-0.9870022.4591021.16570HepG2SRSF9
NGEFENSG00000066248.10657.887501030.50410-0.647404.058702.52710HepG2SSRP1
NGEFENSG00000066248.10755.87210564.043800.422203.324802.29980HepG2SUPT6H
NGEFENSG00000066248.10766.18890476.841100.684103.759602.93080HepG2TARDBP
NGEFENSG00000066248.101031.64820453.220101.1866025.1105023.88980HepG2TIAL1
NGEFENSG00000066248.10917.61930457.277001.0047022.4837021.07690HepG2TRIM56
NGEFENSG00000066248.10283.56830714.59060-1.3334018.0740016.41370HepG2U2AF1
NGEFENSG00000066248.10122.51510584.83370-2.2551010.740008.69590HepG2U2AF2
NGEFENSG00000066248.101022.88810733.618000.479403.467702.52790HepG2UBE2L3
NGEFENSG00000066248.10291.47650733.00730-1.3304012.1706011.05110HepG2UTP3
NGEFENSG00000066248.10727.21070447.740100.699604.822003.35940HepG2XPO5
NGEFENSG00000066248.10456.80220630.35340-0.464602.270801.31340HepG2XRCC6
NGEFENSG00000066248.10572.41510681.80120-0.252301.951501.37230HepG2ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NGEF is not available on ENCORE database.






No RBPs affect the alternative splcing events of NGEF on ENCORE database.





The Knockdown/knockout RNA-Seq assay for NGEF is not avaliable on ENCORE database.