MPI

General Information

Gene Name       : MPI
Gene ID             : ENSG00000178802.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MPI)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MPIENSG00000178802.1732.7063.8948.30ENCSR000AEF
HepG2MPIENSG00000178802.1757.6344.5951.11ENCSR985KAT
K562MPIENSG00000178802.1756.8370.5563.69ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MPI is not avaliable on ENCORE database.



Proteins bound to RNA
  • MPI RNA is bound by 5 proteins.  







eCLIP assay for MPI is not avaliable on ENCORE database.





5 proteins are bound to MPI RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr157518559875185661+3'-UTR,CDS,intron-Distal4.577363.49905HepG2PPIG
chr157518870275188850+3'-UTR,CDS,intron-Distal,intron-Proximal4.010929.89875K562PRPF8
chr157519012375190248+3'-UTR5.033835.63383K562UPF1
chr157518849375188554+3'-UTR,CDS,intron-Distal3.127123.05161HepG2PPIG
chr157519006875190213+3'-UTR4.087538.16501HepG2UPF1
chr157519024975190331+3'-UTR4.510184.56348K562UPF1
chr157519036475190421+3'-UTR4.520925.86108K562YBX3
chr157518294275182995+5'-UTR,CDS,intron-Distal4.290024.95438K562YBX3
chr157518371975183804+5'-UTR,CDS,intron-Proximal3.220614.29172K562YBX3
chr157518380475183923+5'-UTR,CDS,intron-Proximal3.678356.59132K562YBX3
chr157518514375185146+intron-Distal,intron-Proximal4.743364.65563K562AQR
chr157518514675185197+intron-Distal,intron-Proximal5.445567.28294K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MPI is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MPI is not available on ENCORE database.

  • 107 RBPs can affect the levels of MPI.  








The Knockdown/knockout RNA-Seq assay for MPI is not available on ENCORE database.





107 RBPs can affect the gene expression of MPI :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MPIENSG00000178802.13719.285801084.42610-0.5923010.493609.46910HepG2ACO1
MPIENSG00000178802.13708.37290932.81660-0.397102.801301.79940HepG2ADAR
MPIENSG00000178802.131287.845901782.38520-0.468803.396302.81510HepG2AKAP1
MPIENSG00000178802.13818.912101089.46210-0.411805.152404.13410HepG2AKAP8L
MPIENSG00000178802.13866.487701446.42950-0.7392016.4509015.02820HepG2AUH
MPIENSG00000178802.13657.78870921.02440-0.485604.741803.76590HepG2CALR
MPIENSG00000178802.13983.592901401.15150-0.510504.537103.56020HepG2CIRBP
MPIENSG00000178802.13570.725801084.11960-0.9257023.9161022.39490HepG2CKAP4
MPIENSG00000178802.13356.12880496.78080-0.480202.994501.87770HepG2CSTF2
MPIENSG00000178802.13831.440401002.90620-0.270502.776201.94090HepG2DDX19B
MPIENSG00000178802.13702.45710948.89490-0.433802.414901.56720HepG2DDX24
MPIENSG00000178802.13629.614901707.44000-1.4393027.9513026.18760HepG2DDX3X
MPIENSG00000178802.13934.76760727.175100.362202.597201.33940HepG2DDX47
MPIENSG00000178802.13696.094101037.48360-0.575708.534407.47510HepG2DKC1
MPIENSG00000178802.13690.87180927.59630-0.425102.835401.90440HepG2EEF2
MPIENSG00000178802.13522.88130773.29260-0.564504.560703.13420HepG2EFTUD2
MPIENSG00000178802.131125.495101410.00320-0.325101.976501.46570HepG2EIF2S1
MPIENSG00000178802.13671.13270968.84660-0.529705.814504.16400HepG2EIF2S2
MPIENSG00000178802.13540.57460753.00290-0.478203.112702.15900HepG2EIF3D
MPIENSG00000178802.13757.688201558.27570-1.0403013.7448012.34130HepG2EIF4A3
MPIENSG00000178802.13946.556801517.09250-0.680505.225204.30070HepG2EIF4B
MPIENSG00000178802.131079.129701413.05310-0.388902.913902.07910HepG2EIF4G2
MPIENSG00000178802.13620.999301660.77680-1.4192055.1967053.14680HepG2ETF1
MPIENSG00000178802.13562.583001059.61520-0.9134014.7548012.91730HepG2EWSR1
MPIENSG00000178802.13847.23450672.994700.332102.599101.46900HepG2FAM120A
MPIENSG00000178802.13756.989901289.96700-0.769007.448606.25030HepG2FIP1L1
MPIENSG00000178802.131143.895201572.06430-0.458703.765802.96860HepG2FXR1
MPIENSG00000178802.131062.592901458.40990-0.456803.450002.71080HepG2G3BP1
MPIENSG00000178802.131238.202001548.17180-0.322302.172301.38850HepG2G3BP2
MPIENSG00000178802.13733.534101010.11020-0.461603.432702.29320HepG2GNB2L1
MPIENSG00000178802.13386.71490555.70330-0.523002.564401.49500HepG2GRSF1
MPIENSG00000178802.13729.50520948.31820-0.378502.647302.01260HepG2HNRNPA1
MPIENSG00000178802.13574.569201054.81450-0.8764011.8307010.48390HepG2HNRNPC
MPIENSG00000178802.13417.293001476.56270-1.8231045.3813042.87370HepG2HNRNPK
MPIENSG00000178802.13834.392701047.84180-0.328603.598802.91590HepG2HNRNPU
MPIENSG00000178802.13654.657501482.47370-1.1792019.5221017.91360HepG2IGF2BP2
MPIENSG00000178802.13680.391601391.10900-1.031804.383003.15160HepG2IGF2BP3
MPIENSG00000178802.13974.477501491.05550-0.613604.643303.31400HepG2KHSRP
MPIENSG00000178802.131245.98310991.257400.329904.491903.20430HepG2KIF1C
MPIENSG00000178802.13861.094201414.74530-0.716306.305005.04090HepG2LARP4
MPIENSG00000178802.13766.37520989.66750-0.368902.858201.70730HepG2LARP7
MPIENSG00000178802.13898.461701572.61240-0.807609.800708.58570HepG2MAGOH
MPIENSG00000178802.131185.057701581.44190-0.416302.826702.18970HepG2MATR3
MPIENSG00000178802.13628.372001043.63640-0.731909.754708.32630HepG2MSI2
MPIENSG00000178802.13868.57290617.735500.491602.403001.50580HepG2MTPAP
MPIENSG00000178802.13956.313201618.71620-0.759308.688307.59910HepG2NCBP2
MPIENSG00000178802.13298.19660548.68790-0.879705.121003.88280HepG2PABPC1
MPIENSG00000178802.13934.948001435.11840-0.6182010.701309.63320HepG2PCBP1
MPIENSG00000178802.13379.94730941.12450-1.3086014.1551012.07840HepG2PCBP2
MPIENSG00000178802.13174.15450609.98180-1.8084026.6064024.51120HepG2PRPF8
MPIENSG00000178802.131006.645001460.20810-0.536608.990608.11740HepG2PTBP1
MPIENSG00000178802.13935.565201415.21100-0.597107.061206.16530HepG2PUF60
MPIENSG00000178802.13765.113001502.39530-0.9735018.8512017.58290HepG2PUM1
MPIENSG00000178802.131227.152601501.24420-0.290802.296401.68320HepG2PUM2
MPIENSG00000178802.13326.97720908.21880-1.4738013.4293011.98510HepG2RAVER1
MPIENSG00000178802.13580.653201388.08490-1.2573035.0199033.57800HepG2RBM22
MPIENSG00000178802.13920.165501435.34840-0.641409.108407.94050HepG2RBM25
MPIENSG00000178802.13955.800401193.38850-0.320302.177301.30740HepG2RBM27
MPIENSG00000178802.131074.529901625.13670-0.596909.870108.96420HepG2NELFE
MPIENSG00000178802.131193.540401513.47550-0.342604.488003.72750HepG2RECQL
MPIENSG00000178802.13728.32100897.04370-0.300601.954601.36820HepG2RPLP0
MPIENSG00000178802.13499.19800892.12610-0.837606.180404.80770HepG2RPS10
MPIENSG00000178802.13437.44660732.70650-0.744108.424407.42160HepG2RPS19
MPIENSG00000178802.13657.086501100.60300-0.744108.641707.28520HepG2RPS2
MPIENSG00000178802.13229.40250603.39130-1.3952016.0719014.45720HepG2RRP9
MPIENSG00000178802.131277.87910933.157700.453507.329706.35280HepG2SAFB2
MPIENSG00000178802.13555.63980735.38280-0.404302.558701.65300HepG2SERBP1
MPIENSG00000178802.13379.311001062.42610-1.4859020.0247018.16530HepG2SF3A3
MPIENSG00000178802.13427.95220599.36090-0.486003.297602.53310HepG2SF3B1
MPIENSG00000178802.13630.914401520.40600-1.2689021.7734020.37530HepG2SF3B4
MPIENSG00000178802.13841.009301088.23360-0.371805.147004.31500HepG2SMN1
MPIENSG00000178802.13956.26060666.906500.519802.646201.88240HepG2SNRNP70
MPIENSG00000178802.13734.555701567.76050-1.0938037.7191036.42340HepG2SRFBP1
MPIENSG00000178802.13869.363901586.91720-0.8682017.2406016.27380HepG2SRSF1
MPIENSG00000178802.13362.47030645.01330-0.831506.206604.65660HepG2SRSF3
MPIENSG00000178802.13928.245101397.41820-0.590206.961306.03140HepG2SRSF5
MPIENSG00000178802.131024.555601290.99210-0.333502.752602.20220HepG2SRSF9
MPIENSG00000178802.131340.318301589.16090-0.245702.129901.57060HepG2SUCLG1
MPIENSG00000178802.13447.36250787.22770-0.815307.323406.30690HepG2SUPV3L1
MPIENSG00000178802.13878.573201426.22350-0.6990010.664809.67850HepG2TAF15
MPIENSG00000178802.13313.84120527.63850-0.749505.184603.88310HepG2TFIP11
MPIENSG00000178802.13555.746701018.22700-0.8736014.4986013.51200HepG2TIAL1
MPIENSG00000178802.13873.750701027.27240-0.233501.922501.43570HepG2TRIM56
MPIENSG00000178802.13312.414301103.26730-1.8202026.8837024.86630HepG2U2AF1
MPIENSG00000178802.13299.63130604.62440-1.012902.915301.89940HepG2U2AF2
MPIENSG00000178802.131038.911501463.70360-0.494603.450202.51320HepG2UBE2L3
MPIENSG00000178802.13225.97230465.02550-1.0412010.094208.64680HepG2UCHL5
MPIENSG00000178802.13714.74410942.20860-0.398604.799803.92180HepG2UPF1
MPIENSG00000178802.13735.243501071.19800-0.542909.131308.03000HepG2ZC3H8
MPIENSG00000178802.13702.942201036.25050-0.5599010.028809.15000HepG2ZNF622
MPIENSG00000178802.13660.39950907.36700-0.458302.594301.34310HepG2ZRANB2
MPIENSG00000178802.131103.841001409.54440-0.352702.935302.26190K562AKAP8L
MPIENSG00000178802.131615.017202015.08940-0.319302.507601.33120K562APOBEC3C
MPIENSG00000178802.13847.356601741.40320-1.0392012.3697011.25660K562AQR
MPIENSG00000178802.132339.375302808.13460-0.263502.707001.74320K562CELF1
MPIENSG00000178802.131253.957001516.84330-0.274602.723101.85690K562DKC1
MPIENSG00000178802.13730.776501079.00020-0.562203.887002.33480K562EEF2
MPIENSG00000178802.13481.052101042.53360-1.1158017.0375014.58180K562EFTUD2
MPIENSG00000178802.131127.53000889.828200.341503.670102.25730K562EIF2S1
MPIENSG00000178802.13903.358901200.70620-0.410504.347203.47330K562EIF2S2
MPIENSG00000178802.13502.114701116.25040-1.1526015.1734012.58040K562EIF3D
MPIENSG00000178802.131422.775302283.71690-0.6827015.4733013.35880K562EIF4G2
MPIENSG00000178802.131198.13560893.259900.423503.747202.74920K562FIP1L1
MPIENSG00000178802.13501.91820880.19240-0.8104013.1770011.95590K562FXR1
MPIENSG00000178802.13284.55230612.98330-1.1072010.295008.76580K562G3BP2
MPIENSG00000178802.13890.553901186.93080-0.414502.823901.67160K562GLRX3
MPIENSG00000178802.13634.10470834.55930-0.396302.903302.08960K562GPKOW
MPIENSG00000178802.13505.847001051.86260-1.0562017.8745016.43990K562HNRNPC
MPIENSG00000178802.13459.48230937.95180-1.0295010.273807.86030K562HNRNPK
MPIENSG00000178802.131862.497301418.351600.392904.114202.79770K562HNRNPL
MPIENSG00000178802.13758.42650987.15620-0.380302.414201.62600K562MAGOH
MPIENSG00000178802.131267.45440985.059500.363603.090602.11280K562MATR3
MPIENSG00000178802.131034.886201247.90470-0.270002.787001.97400K562MTPAP
MPIENSG00000178802.13849.284201174.61230-0.467902.844201.94740K562NAA15
MPIENSG00000178802.13358.76110878.21170-1.2915014.6663012.30860K562PCBP2
MPIENSG00000178802.131427.587102346.59680-0.7170013.2509010.73180K562PNPT1
MPIENSG00000178802.131350.505901014.139400.413103.412902.48620K562PPIG
MPIENSG00000178802.13290.311301014.50490-1.8051036.4770033.81710K562PRPF8
MPIENSG00000178802.131045.352302491.68990-1.2531031.2915028.56140K562PUF60
MPIENSG00000178802.132030.762302650.42800-0.384204.938403.47930K562PUM1
MPIENSG00000178802.132186.982202596.76720-0.247802.798701.83470K562PUM2
MPIENSG00000178802.13355.70260584.81980-0.717303.628701.96580K562RAVER1
MPIENSG00000178802.131098.509101517.50690-0.466205.228603.03030K562RBM17
MPIENSG00000178802.13797.397001033.39660-0.374002.084401.37970K562RPS19
MPIENSG00000178802.13778.40050979.55420-0.331602.405001.39940K562SAFB
MPIENSG00000178802.13523.19220868.13530-0.730604.833902.77550K562SERBP1
MPIENSG00000178802.131009.875901368.16010-0.438105.654204.51810K562SF3A3
MPIENSG00000178802.13434.02700793.78160-0.871008.275106.53080K562SF3B1
MPIENSG00000178802.13394.27400637.21170-0.692607.828006.34810K562SF3B4
MPIENSG00000178802.13479.19370931.53120-0.959004.958403.16330K562SNRNP200
MPIENSG00000178802.131071.37070815.750400.393203.071101.97680K562SRFBP1
MPIENSG00000178802.131088.213101401.71080-0.365205.330704.08110K562SRPK2
MPIENSG00000178802.13741.93870982.27650-0.404802.527501.56180K562SUPV3L1
MPIENSG00000178802.13868.760801102.59660-0.343902.379701.61820K562SYNCRIP
MPIENSG00000178802.13600.20290951.53270-0.664805.692604.65690K562TARDBP
MPIENSG00000178802.13296.45030593.97400-1.002609.658007.43940K562U2AF1
MPIENSG00000178802.13300.14640613.51330-1.0314014.5622012.69660K562U2AF2
MPIENSG00000178802.131129.532301454.73740-0.365002.442201.32030K562UTP3
MPIENSG00000178802.131349.801501961.43220-0.539205.069803.84580K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MPI is not available on ENCORE database.





11 RBPs can affect the splicing of MPI :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMPIENSG00000178802.13chr15+751854787518566175185001751851437518849275189271-0.069000.000960.02023excludedK562SRSF1
SEMPIENSG00000178802.13chr15+751893517518956075188492751886667518985275190569-0.282000.000360.00918excludedK562SRSF1
SEMPIENSG00000178802.13chr15+751893517518956075188492751886667518985275190569-0.261000.000010.00049excludedHepG2U2AF1
SEMPIENSG00000178802.13chr15+751893517518956075188492751886667518985275190569-0.531000.000000.00000excludedHepG2U2AF2
SEMPIENSG00000178802.13chr15+751893517518956075188492751886667518985275190569-0.350000.000020.00066excludedK562U2AF1
SEMPIENSG00000178802.13chr15+7518935175189560751884927518866675189852751905690.104000.000080.02125includedHepG2RBM15
SEMPIENSG00000178802.13chr15+751893517518956075188492751886667518985275190569-0.314000.000000.00000excludedHepG2SRSF1
SEMPIENSG00000178802.13chr15+751893517518956075188492751886667518985275190569-0.169000.000050.01071excludedHepG2SSB
SEMPIENSG00000178802.13chr15+751828677518299575182382751824307518371975183920-0.149000.000810.05632excludedHepG2IGF2BP3
SEMPIENSG00000178802.13chr15+751893517518956075188492751886667518985275190569-0.117000.003970.09407excludedK562UTP18
SEMPIENSG00000178802.13chr15+751893517518956075188492751886667518985275190569-0.366000.001130.02209excludedK562U2AF2
SEMPIENSG00000178802.13chr15+751893517518956075188492751886667518985275190569-0.291000.002020.06393excludedK562TARDBP
SEMPIENSG00000178802.13chr15+7518935175189560751884927518866675189852751905690.173000.000130.03740includedHepG2EIF3D
SEMPIENSG00000178802.13chr15+751893517518956075188492751886667518985275190569-0.301000.000000.00008excludedHepG2HNRNPC
SEMPIENSG00000178802.13chr15+751893517518956075188492751886667518985275190569-0.429000.000000.00000excludedK562HNRNPC
A5SSMPIENSG00000178802.13chr15+7518238275182542751823827518243075182867751829950.172000.000010.00362longerHepG2HNRNPU

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MPI is not avaliable on ENCORE database.