LGMN

General Information

Gene Name       : LGMN
Gene ID             : ENSG00000100600.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LGMN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LGMNENSG00000100600.142.762.912.83ENCSR000AEF
HepG2LGMNENSG00000100600.1473.8850.3562.11ENCSR985KAT
K562LGMNENSG00000100600.140.260.180.22ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LGMN is not avaliable on ENCORE database.



Proteins bound to RNA
  • LGMN RNA is bound by 18 proteins.  







eCLIP assay for LGMN is not avaliable on ENCORE database.





18 proteins are bound to LGMN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr149317608893176169-3'-UTR,CDS,intron-Distal4.6436616.81720HepG2SND1
chr149317290893172962-3'-UTR,CDS,intron-Distal4.2880816.52613HepG2SND1
chr149317065193170701-3'-UTR,CDS,intron-Distal3.364965.69819HepG2SND1
chr149317017893170236-3'-UTR,intron-Distal,intron-Proximal4.160634.67754HepG2FUBP3
chr149317029093170407-3'-UTR,intron-Distal3.615664.17167HepG2ZC3H11A
chr149317612193176177-3'-UTR,CDS,intron-Distal3.693936.31999HepG2PCBP2
chr149317282693172845-3'-UTR,CDS,intron-Distal,intron-Proximal4.9188614.71009HepG2SND1
chr149317284593172908-3'-UTR,CDS,intron-Distal5.0515330.33237HepG2SND1
chr149317051993170613-3'-UTR,CDS,intron-Distal,intron-Proximal3.668625.40760HepG2UPF1
chr149317297293172998-3'-UTR,CDS,intron-Distal3.037145.78035HepG2SND1
chr149318077193180796-3'-UTR,CDS,intron-Distal4.864966.50673HepG2SND1
chr149317804593178089-3'-UTR,CDS,intron-Distal,intron-Proximal3.524975.82787HepG2SND1
chr149317102493171052-3'-UTR,CDS,intron-Distal5.385038.83160HepG2SND1
chr149317601793176068-3'-UTR,CDS,intron-Distal3.7766510.81522HepG2SND1
chr149317098993171024-3'-UTR,CDS,intron-Distal3.728454.95361HepG2SND1
chr149318256493182567-3'-UTR,CDS,intron-Distal,intron-Proximal3.330223.77917HepG2SND1
chr149317824493178286-3'-UTR,CDS,intron-Distal3.902415.26719HepG2SND1
chr149318248093182543-3'-UTR,CDS,intron-Distal,intron-Proximal4.9400614.05085HepG2SND1
chr149317057493170690-3'-UTR,CDS,intron-Distal,intron-Proximal3.762288.26434HepG2LARP4
chr149318372493183777-3'-UTR,CDS,intron-Distal,intron-Proximal3.9771310.12959HepG2SND1
chr149317033193170422-3'-UTR,intron-Distal3.7494213.25408HepG2LARP4
chr149317820993178237-3'-UTR,CDS,intron-Distal3.818265.86703HepG2SND1
chr149317035193170415-3'-UTR,intron-Distal4.794444.18952HepG2SUB1
chr149321483893214961-5'-UTR,intron-Distal,intron-Proximal4.7548642.68137HepG2DDX3X
chr149319906893199113-CDS,intron-Distal,intron-Proximal3.960436.70369HepG2RPS3
chr149318515793185188-CDS,intron-Distal3.446153.57831HepG2SND1
chr149318511693185191-CDS,intron-Distal,intron-Proximal4.214148.70605HepG2LIN28B
chr149318562593185669-intron-Distal4.237684.94392K562AKAP1
chr149318565393185670-intron-Distal5.765838.20191HepG2FXR2
chr149318562293185670-intron-Distal4.4512321.19850HepG2G3BP1
chr149318562493185653-intron-Distal3.765835.78876HepG2FXR2
chr149318565193185670-intron-Distal5.6035510.93867K562NIPBL
chr149318562793185672-intron-Distal3.760134.12529K562GTF2F1
chr149318560293185674-intron-Distal3.224205.79450HepG2XPO5
chr149318562193185669-intron-Distal3.471105.88441K562AATF
chr149318562393185651-intron-Distal4.7160810.50492K562NIPBL
chr149318561193185667-intron-Distal5.808445.14353K562CPEB4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LGMN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LGMN is not available on ENCORE database.

  • 90 RBPs can affect the levels of LGMN.  








The Knockdown/knockout RNA-Seq assay for LGMN is not available on ENCORE database.





90 RBPs can affect the gene expression of LGMN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LGMNENSG00000100600.101300.52790938.951100.469904.596903.24650HepG2AATF
LGMNENSG00000100600.10866.676801499.82690-0.791209.407707.82900HepG2ABCF1
LGMNENSG00000100600.101741.862601107.263900.6535016.4626015.24310HepG2ACO1
LGMNENSG00000100600.10553.046801098.41010-0.9899014.1418012.16360HepG2ADAR
LGMNENSG00000100600.103491.862101568.003501.1550019.1523017.88310HepG2AKAP1
LGMNENSG00000100600.101812.280901336.644700.439103.292402.16270HepG2AKAP8
LGMNENSG00000100600.101394.542801112.430800.326003.877002.98200HepG2AKAP8L
LGMNENSG00000100600.101919.859201544.087700.314103.721202.94650HepG2AUH
LGMNENSG00000100600.101706.226501258.644200.438805.283004.25960HepG2CALR
LGMNENSG00000100600.102757.489201878.986800.553304.421703.17290HepG2CCAR1
LGMNENSG00000100600.102477.701801428.239900.7947022.1764020.71510HepG2CELF1
LGMNENSG00000100600.101782.225401535.797300.214602.401301.70430HepG2DAZAP1
LGMNENSG00000100600.10850.774701024.04090-0.267402.789001.95230HepG2DDX19B
LGMNENSG00000100600.103069.201301502.014701.0309017.8106016.36820HepG2DDX3X
LGMNENSG00000100600.10742.901201177.14130-0.664007.330705.75710HepG2DDX5
LGMNENSG00000100600.102231.936401290.294900.790509.095308.04470HepG2DDX6
LGMNENSG00000100600.10718.432401059.34050-0.560208.295407.24510HepG2DKC1
LGMNENSG00000100600.101255.22930848.355800.565105.005603.81560HepG2EIF3D
LGMNENSG00000100600.10617.56880978.15480-0.663508.317006.63800HepG2EIF3G
LGMNENSG00000100600.10992.05270758.400500.387403.452202.12840HepG2FAM120A
LGMNENSG00000100600.10760.30040987.04870-0.376602.975801.79270HepG2FASTKD2
LGMNENSG00000100600.102734.126301514.383600.8522010.756509.37940HepG2FIP1L1
LGMNENSG00000100600.101958.652701181.358600.729306.110004.49870HepG2FUS
LGMNENSG00000100600.101728.977701282.959700.430303.267602.54820HepG2G3BP1
LGMNENSG00000100600.10688.61190945.19340-0.456903.085302.41400HepG2GPKOW
LGMNENSG00000100600.101719.168401280.403500.425002.338901.31400HepG2GRSF1
LGMNENSG00000100600.101413.549201057.094300.419106.262204.86650HepG2HDGF
LGMNENSG00000100600.10864.249101116.63120-0.369602.919702.25700HepG2HNRNPA1
LGMNENSG00000100600.101872.488401299.172200.527305.676804.70460HepG2HNRNPK
LGMNENSG00000100600.101935.945101399.020700.4685010.522609.28620HepG2HNRNPL
LGMNENSG00000100600.10903.573601233.84170-0.449406.738905.83120HepG2HNRNPU
LGMNENSG00000100600.10904.693601292.75790-0.515006.300305.25120HepG2IGF2BP1
LGMNENSG00000100600.10855.920701311.71010-0.615904.635503.30760HepG2KHSRP
LGMNENSG00000100600.102708.883401984.314900.449003.122302.23730HepG2LARP4
LGMNENSG00000100600.10872.494401383.53670-0.665106.779405.76670HepG2MAGOH
LGMNENSG00000100600.101284.73280887.816100.533002.925901.84380HepG2METAP2
LGMNENSG00000100600.101866.595101225.283500.607208.024506.71250HepG2MSI2
LGMNENSG00000100600.101426.968501028.961100.471704.817403.21890HepG2NAA15
LGMNENSG00000100600.102352.263601424.038300.724008.640607.55430HepG2NCBP2
LGMNENSG00000100600.101320.79340823.626700.681203.515202.27450HepG2NONO
LGMNENSG00000100600.101482.726301221.281700.279803.075402.18600HepG2PARN
LGMNENSG00000100600.10928.448201330.59600-0.519208.450307.48450HepG2PCBP1
LGMNENSG00000100600.101393.182601100.486800.340103.776802.92810HepG2PPIL4
LGMNENSG00000100600.10764.359201171.98060-0.6166010.590409.22000HepG2PRPF4
LGMNENSG00000100600.102491.357501542.034800.6920013.6291012.20800HepG2PUM2
LGMNENSG00000100600.101268.183001506.80600-0.248702.394201.88470HepG2NELFE
LGMNENSG00000100600.10789.298401414.19030-0.8413012.7581011.48200HepG2RPLP0
LGMNENSG00000100600.10839.771701389.66930-0.726704.158303.17700HepG2RPS3A
LGMNENSG00000100600.10486.91930892.78430-0.8746010.810309.50090HepG2SF3B1
LGMNENSG00000100600.10972.523501409.58880-0.535508.795507.83220HepG2SF3B4
LGMNENSG00000100600.102151.55350993.393001.1148011.7626010.16250HepG2SNRNP70
LGMNENSG00000100600.101169.23360854.164700.452902.994001.31000HepG2SRP68
LGMNENSG00000100600.101558.92320960.749500.698206.261404.70380HepG2SRSF3
LGMNENSG00000100600.101936.898901435.288100.432307.326906.37560HepG2SRSF5
LGMNENSG00000100600.10969.386601289.79500-0.412005.530704.60250HepG2SRSF7
LGMNENSG00000100600.10869.110601453.05260-0.7415017.6224016.56360HepG2SSB
LGMNENSG00000100600.101911.657701632.347700.227802.687802.07250HepG2SUCLG1
LGMNENSG00000100600.101035.050701468.08690-0.504203.382501.90250HepG2SUGP2
LGMNENSG00000100600.101926.032501322.568000.542209.637108.69240HepG2TAF15
LGMNENSG00000100600.101674.384401215.178700.462405.734104.54240HepG2TIA1
LGMNENSG00000100600.10774.996001198.87680-0.629408.955508.14740HepG2TIAL1
LGMNENSG00000100600.10698.320601295.25190-0.8913013.0475011.64730HepG2U2AF1
LGMNENSG00000100600.101460.620201099.381900.409806.365905.37810HepG2UPF1
LGMNENSG00000100600.101348.895801130.002700.255402.449501.45260HepG2UTP18
LGMNENSG00000100600.101766.408701061.408400.7347019.2927017.93000HepG2UTP3
LGMNENSG00000100600.10529.486401061.26140-1.003108.922906.74030HepG2XRCC5
LGMNENSG00000100600.10547.00920878.83090-0.684006.319005.23840HepG2XRN2
LGMNENSG00000100600.10964.651601156.57600-0.261802.736002.06740HepG2ZC3H8
LGMNENSG00000100600.101737.098201209.108100.5226012.5151011.56260HepG2ZNF622
LGMNENSG00000100600.10111.7050060.187200.892103.490802.75320K562AKAP8L
LGMNENSG00000100600.10111.1079028.982701.938608.035007.12270K562AQR
LGMNENSG00000100600.1048.7851016.913501.528202.894102.00250K562BOP1
LGMNENSG00000100600.10109.9939027.510001.999307.546305.74220K562CNOT7
LGMNENSG00000100600.1069.8766017.982601.958106.007004.85550K562CPSF6
LGMNENSG00000100600.1059.9257018.299501.711304.247103.18770K562FMR1
LGMNENSG00000100600.1048.8030015.511601.653503.522702.48240K562FTO
LGMNENSG00000100600.1011.3229031.33200-1.468402.134201.59040K562FXR1
LGMNENSG00000100600.1069.6120017.167802.019506.029704.85670K562GPKOW
LGMNENSG00000100600.1099.2672021.853202.183408.115506.81000K562GRSF1
LGMNENSG00000100600.1067.4357024.007101.490004.541203.17140K562HNRNPA1
LGMNENSG00000100600.1090.8410042.006901.112602.534401.38220K562HNRNPA2B1
LGMNENSG00000100600.1042.8297014.662101.546402.524601.63540K562KRR1
LGMNENSG00000100600.10100.0435041.298601.276404.442803.01120K562MSI2
LGMNENSG00000100600.1075.3820022.624001.736305.855904.70980K562MTPAP
LGMNENSG00000100600.1059.7014025.140801.247602.971602.20190K562NSUN2
LGMNENSG00000100600.10106.7961036.738501.539404.344603.02990K562PABPN1
LGMNENSG00000100600.10114.8526043.672301.394903.994602.12320K562PPP1R8
LGMNENSG00000100600.108.4406036.28860-2.104104.368503.55150K562PTBP1
LGMNENSG00000100600.1012.1715036.63480-1.589702.926101.79780K562NELFE
LGMNENSG00000100600.1049.83970105.40390-1.080603.074202.01370K562RPS3
LGMNENSG00000100600.1056.0764024.802301.176802.614101.82050K562SF3A3
LGMNENSG00000100600.1044.1077016.331201.433302.456901.54410K562SF3B1
LGMNENSG00000100600.1080.6593036.885001.128703.356501.70400K562SUCLG1
LGMNENSG00000100600.10120.1526046.152401.380303.826002.03950K562SUPT6H
LGMNENSG00000100600.1011.4350033.05800-1.531502.399401.63540K562SYNCRIP
LGMNENSG00000100600.1047.6377021.401101.154302.129701.31990K562TIAL1
LGMNENSG00000100600.1048.8672018.032401.438202.730301.36070K562TRIP6
LGMNENSG00000100600.1038.8766012.169701.675502.569101.59290K562UCHL5
LGMNENSG00000100600.1079.0020026.657001.567303.898803.05840K562UPF1
LGMNENSG00000100600.10193.7412060.518601.678609.190406.47640K562UTP18
LGMNENSG00000100600.1098.4990022.810002.110309.883008.19110K562WDR3
LGMNENSG00000100600.10105.8608032.637501.697508.070006.47630K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LGMN is not available on ENCORE database.





4 RBPs can affect the splicing of LGMN :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELGMNENSG00000100600.10chr14-9317098493171052931701539317070693176016931762170.115000.000860.01814includedHepG2U2AF1
SELGMNENSG00000100600.10chr14-931709849317105293170153931707069317601693176217-0.188000.000010.00248excludedHepG2SRSF7
SELGMNENSG00000100600.10chr14-931709849317105293170153931707069317601693176217-0.149000.002100.05458excludedHepG2SF3A3
MXELGMNENSG00000100600.10chr14-93170984931710529317282793172998931701539317070693176016931762170.065000.001570.021131includedHepG2SFPQ

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LGMN is not avaliable on ENCORE database.