KLHL17

General Information

Gene Name       : KLHL17
Gene ID             : ENSG00000187961.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: KLHL17)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KLHL17ENSG00000187961.130.201.550.88ENCSR000AEF
HepG2KLHL17ENSG00000187961.1323.132.9813.05ENCSR985KAT
K562KLHL17ENSG00000187961.1316.004.8410.42ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KLHL17 is not avaliable on ENCORE database.



Proteins bound to RNA
  • KLHL17 RNA is bound by 31 proteins.  







eCLIP assay for KLHL17 is not avaliable on ENCORE database.





31 proteins are bound to KLHL17 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1900995901052+3'-UTR3.609205.29391HepG2LSM11
chr1900720900770+3'-UTR5.186609.60250K562DDX55
chr1900945900995+3'-UTR3.507264.91603HepG2LSM11
chr1900764900797+3'-UTR4.427425.23207HepG2ZC3H11A
chr1900716900764+3'-UTR3.801655.45754HepG2ZC3H11A
chr1900720900848+3'-UTR4.5292416.43475HepG2PABPN1
chr1900720900806+3'-UTR4.058074.74249HepG2DDX55
chr1899229899301+3'-UTR,CDS,intron-Proximal4.561919.28995HepG2PRPF8
chr1899736899803+3'-UTR,CDS4.402354.78834HepG2PABPN1
chr1899487899542+3'-UTR,CDS3.354966.23940HepG2PPIG
chr1899320899383+3'-UTR,CDS4.0846810.98900HepG2PPIG
chr1899865899900+3'-UTR,CDS3.869844.68902HepG2PPIG
chr1900719900836+3'-UTR5.7227221.62761K562ZC3H11A
chr1899743899829+3'-UTR,CDS3.619118.10600HepG2PPIG
chr1898727898776+5'-UTR,CDS3.324144.25147HepG2LSM11
chr1895985896116+5'-UTR,CDS3.583464.77429HepG2NCBP2
chr1898881898929+5'-UTR,CDS,intron-Proximal5.468719.06713HepG2PRPF8
chr1896058896136+5'-UTR,CDS3.371793.00221HepG2CSTF2T
chr1896591896683+CDS,intron-Proximal4.444949.27995K562PRPF8
chr1896953897011+CDS,intron-Proximal5.5617717.94355HepG2SF3A3
chr1898485898525+CDS,intron-Proximal4.319184.82934K562RBM15
chr1896955897037+CDS,intron-Proximal5.6521350.54467K562SF3B4
chr1896952897011+CDS,intron-Proximal3.381168.82117K562BUD13
chr1896954897015+CDS,intron-Proximal4.555234.69676K562XRN2
chr1898178898239+CDS3.627128.74774HepG2PPIG
chr1896619896710+CDS,intron-Proximal4.9879617.43386K562SF3B4
chr1896943897015+CDS,intron-Proximal4.6166523.87999HepG2SF3B4
chr1897850897902+CDS,intron-Proximal3.767367.16774K562AQR
chr1900346900422+CDS3.583645.05725HepG2PABPN1
chr1898603898671+CDS,intron-Proximal3.061747.39618HepG2PRPF8
chr1897845897908+CDS,intron-Proximal3.6580712.48166HepG2PRPF8
chr1896996897023+CDS,intron-Proximal3.848785.61068HepG2PRPF8
chr1896586896705+CDS,intron-Proximal4.2346710.30373HepG2EFTUD2
chr1897205897222+CDS,intron-Proximal3.491475.86107HepG2PPIG
chr1897399897429+CDS,intron-Proximal4.255784.42734K562UCHL5
chr1898591898681+CDS,intron-Proximal4.9771413.67886HepG2EFTUD2
chr1897072897130+CDS3.033258.06634HepG2PPIG
chr1898588898629+CDS4.270705.80295HepG2PPIG
chr1898720898762+CDS3.547455.07297K562BUD13
chr1896924896979+CDS,intron-Proximal3.312015.24055HepG2PRPF8
chr1898217898268+CDS3.229593.63043HepG2GRWD1
chr1897887897979+intron-Distal,intron-Proximal4.6376620.84476HepG2EFTUD2
chr1896283896371+intron-Distal4.395834.69797HepG2DGCR8
chr1896261896373+intron-Distal,intron-Proximal3.8920310.67764HepG2RBFOX2
chr1897486897584+intron-Distal,intron-Proximal3.554716.19545HepG2PCBP2
chr1897480897544+intron-Distal,intron-Proximal3.218805.44303HepG2DDX59
chr1896522896579+intron-Distal,intron-Proximal3.597123.00463HepG2NKRF
chr1896269896365+intron-Distal,intron-Proximal4.576384.07596K562GTF2F1
chr1896269896360+intron-Distal,intron-Proximal3.0564914.95086K562BUD13
chr1896287896353+intron-Distal3.419718.80068K562EFTUD2
chr1896273896326+intron-Distal,intron-Proximal4.1531514.54693HepG2EFTUD2
chr1896283896359+intron-Distal4.065706.77655K562GEMIN5
chr1897560897607+intron-Distal3.515363.87400K562RBFOX2
chr1896326896364+intron-Distal4.536938.44359HepG2EFTUD2
chr1898961899002+intron-Distal,intron-Proximal3.990443.53160K562RBFOX2
chr1896287896368+intron-Distal3.464898.81276K562PRPF8
chr1897598897722+intron-Distal,intron-Proximal3.4133311.36875K562BUD13
chr1896402896460+intron-Distal4.417334.61649HepG2CSTF2T
chr1896273896380+intron-Distal,intron-Proximal3.159678.17578K562DROSHA
chr1896270896368+intron-Distal,intron-Proximal3.753709.80768HepG2PRPF4
chr1896294896361+intron-Distal3.7435812.06681K562SF3B4
chr1896269896360+intron-Distal,intron-Proximal3.005083.87304HepG2FAM120A
chr1897887897955+intron-Distal,intron-Proximal3.995606.61691HepG2RBFOX2
chr1897485897550+intron-Distal,intron-Proximal4.683815.62822K562HNRNPK
chr1897623897715+intron-Distal,intron-Proximal4.423545.31936HepG2HNRNPK
chr1896551896656+intron-Distal,intron-Proximal4.790556.08348HepG2CSTF2T
chr1896277896345+intron-Distal,intron-Proximal3.756356.87242K562DDX24
chr1896373896490+intron-Distal3.905276.13900HepG2RBFOX2
chr1897550897645+intron-Distal,intron-Proximal4.841656.49770K562HNRNPK
chr1898042898082+intron-Proximal6.5306510.88909HepG2SF3A3
chr1896190896240+intron-Proximal3.798916.86323K562SF3B4
chr1897683897731+intron-Proximal3.5319410.18520HepG2SF3B4
chr1896945897001+intron-Proximal3.009584.95862K562EFTUD2
chr1898023898080+intron-Proximal4.2834513.54000K562SF3B4
chr1896949897005+intron-Proximal3.632404.68890K562SMNDC1
chr1896190896253+intron-Proximal3.440455.13321HepG2RBFOX2
chr1898886898919+intron-Proximal4.184883.31283K562PRPF8
chr1897675897727+intron-Proximal3.899738.55183K562SF3B4
chr1896194896256+intron-Proximal5.061418.32990HepG2XRN2
chr1899220899296+intron-Proximal3.692916.56588HepG2SF3B4
chr1897654897721+intron-Proximal3.4296611.18549K562DDX24
chr1899243899298+intron-Proximal3.950198.08874K562SF3B4
chr1899237899284+intron-Proximal3.038265.58907HepG2EFTUD2
chr1896187896248+intron-Proximal3.090084.80002HepG2CSTF2T
chr1896633896673+intron-Proximal4.172003.25678HepG2SF3B4
chr1898024898073+intron-Proximal3.282586.33298HepG2SF3B4
chr1897651897719+intron-Proximal3.513534.80505K562PCBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KLHL17 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KLHL17 is not available on ENCORE database.

  • 111 RBPs can affect the levels of KLHL17.  








The Knockdown/knockout RNA-Seq assay for KLHL17 is not available on ENCORE database.





111 RBPs can affect the gene expression of KLHL17 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KLHL17ENSG00000187961.9650.75650444.762900.549006.416705.57000HepG2ACO1
KLHL17ENSG00000187961.9676.07430482.208200.487402.541201.87870HepG2AUH
KLHL17ENSG00000187961.9298.17180217.831300.452802.013701.49620HepG2BOP1
KLHL17ENSG00000187961.9123.32130200.58620-0.701802.099701.42040HepG2CALR
KLHL17ENSG00000187961.9657.06890444.641900.563306.251805.32470HepG2CKAP4
KLHL17ENSG00000187961.9273.92810199.976900.453901.951701.36340HepG2CPSF6
KLHL17ENSG00000187961.9167.80410105.469100.669902.921601.87510HepG2YBX3
KLHL17ENSG00000187961.9309.97500202.601100.613404.128503.37340HepG2CELF1
KLHL17ENSG00000187961.9295.32870217.843600.438902.453401.74970HepG2DAZAP1
KLHL17ENSG00000187961.9309.82580150.442201.042101.985801.31930HepG2DDX55
KLHL17ENSG00000187961.9481.63420219.503501.133604.788703.99570HepG2DDX6
KLHL17ENSG00000187961.9211.07920103.554901.027304.205903.35480HepG2DNAJC21
KLHL17ENSG00000187961.9248.13470102.651901.2733012.6598011.37360HepG2DNAJC2
KLHL17ENSG00000187961.9519.14000210.783101.300304.254503.52800HepG2EIF2S1
KLHL17ENSG00000187961.9722.60390553.688400.384003.253402.60990HepG2ETF1
KLHL17ENSG00000187961.9281.55340174.962700.686304.022302.58400HepG2FAM120A
KLHL17ENSG00000187961.9341.64680200.328100.770002.411301.46980HepG2FTO
KLHL17ENSG00000187961.9483.05270235.252101.037902.190801.57200HepG2FXR1
KLHL17ENSG00000187961.9404.11760218.053000.890002.217201.61850HepG2G3BP1
KLHL17ENSG00000187961.9370.83430194.422000.931509.567608.33500HepG2HNRNPF
KLHL17ENSG00000187961.91054.73280221.213502.2533041.4377039.04810HepG2HNRNPK
KLHL17ENSG00000187961.9362.65500198.438100.869804.219903.40120HepG2HNRNPL
KLHL17ENSG00000187961.9175.40710115.523900.602402.785402.17560HepG2HNRNPU
KLHL17ENSG00000187961.9272.73300191.449800.510402.637001.92940HepG2IGF2BP1
KLHL17ENSG00000187961.9218.56080118.003200.889106.382205.31330HepG2ILF2
KLHL17ENSG00000187961.9207.31880335.38750-0.694003.802402.85710HepG2MSI2
KLHL17ENSG00000187961.9556.29570242.126401.200005.776804.87670HepG2NCBP2
KLHL17ENSG00000187961.9221.25290130.954900.756503.013101.54040HepG2NIP7
KLHL17ENSG00000187961.9172.1531073.163501.234404.198802.43770HepG2NOLC1
KLHL17ENSG00000187961.9344.06630172.574400.995402.566001.71830HepG2PABPC1
KLHL17ENSG00000187961.9300.15970222.444900.432201.936201.41400HepG2PCBP1
KLHL17ENSG00000187961.9232.46070103.037501.173709.470908.15040HepG2PPIL4
KLHL17ENSG00000187961.9333.08750226.385600.557002.909702.35140HepG2PTBP1
KLHL17ENSG00000187961.9385.35960206.204300.902007.648406.72360HepG2PUF60
KLHL17ENSG00000187961.9461.63130218.895701.0764015.9337014.75050HepG2PUM1
KLHL17ENSG00000187961.9401.63350218.735400.876607.906506.79970HepG2PUM2
KLHL17ENSG00000187961.9350.40250453.01630-0.370502.611002.00780HepG2PUS1
KLHL17ENSG00000187961.9726.67250462.770900.650907.249406.50260HepG2RBM22
KLHL17ENSG00000187961.9304.39410174.684800.801103.060702.01530HepG2RBM27
KLHL17ENSG00000187961.9397.41670251.912600.657602.632602.10240HepG2NELFE
KLHL17ENSG00000187961.9386.59360234.682000.720002.925502.29320HepG2RECQL
KLHL17ENSG00000187961.9324.08660161.077501.008505.711804.58560HepG2RPS2
KLHL17ENSG00000187961.9298.82580164.455500.861502.899301.79640HepG2RPS5
KLHL17ENSG00000187961.9328.72250102.876901.6759022.5405020.94770HepG2SAFB2
KLHL17ENSG00000187961.9562.95210235.625701.2564013.8235012.65750HepG2SF3B4
KLHL17ENSG00000187961.9376.40850197.719300.9287010.075708.86810HepG2SLBP
KLHL17ENSG00000187961.9221.10460119.968100.882005.822004.94350HepG2SMN1
KLHL17ENSG00000187961.9267.18290134.130400.994102.725201.77760HepG2SMNDC1
KLHL17ENSG00000187961.9137.29110245.97120-0.841302.057301.63270HepG2SRSF1
KLHL17ENSG00000187961.9504.24050203.597601.3083021.1443019.63190HepG2SRSF5
KLHL17ENSG00000187961.9258.17270191.014400.434602.159601.53620HepG2SRSF7
KLHL17ENSG00000187961.9214.82260453.76520-1.0788014.5474013.55840HepG2SSB
KLHL17ENSG00000187961.9420.58270165.335401.346905.758904.11890HepG2STIP1
KLHL17ENSG00000187961.9540.87280231.545801.2239020.6004019.15300HepG2SUCLG1
KLHL17ENSG00000187961.9109.91020221.16880-1.008802.958702.38120HepG2TAF15
KLHL17ENSG00000187961.9344.53160112.238901.618003.293902.75590HepG2TIAL1
KLHL17ENSG00000187961.9324.20000113.257501.517209.080008.14930HepG2TRIM56
KLHL17ENSG00000187961.9470.05930201.454101.222302.665901.81010HepG2TUFM
KLHL17ENSG00000187961.9489.18200160.994301.603304.457603.19230HepG2U2AF2
KLHL17ENSG00000187961.9482.78110213.236801.178809.741908.13130HepG2UBE2L3
KLHL17ENSG00000187961.9237.3529088.390701.425005.483504.40810HepG2UCHL5
KLHL17ENSG00000187961.9209.18820336.85850-0.687305.105504.33340HepG2UTP3
KLHL17ENSG00000187961.9338.92110170.107100.994402.642701.57810HepG2XPO5
KLHL17ENSG00000187961.9145.63370208.65630-0.518802.421501.78710HepG2ZC3H8
KLHL17ENSG00000187961.9304.94520383.73350-0.331602.042001.55320HepG2ZNF622
KLHL17ENSG00000187961.9254.15100131.062100.955303.052501.68430HepG2ZRANB2
KLHL17ENSG00000187961.91585.54100631.776501.3274024.5648022.98890K562AGGF1
KLHL17ENSG00000187961.91147.87860694.322000.725206.121204.51690K562AKAP8
KLHL17ENSG00000187961.91369.72700657.415501.058904.219703.41030K562AKAP8L
KLHL17ENSG00000187961.9688.797101019.16400-0.565203.608902.95610K562AQR
KLHL17ENSG00000187961.9988.53320689.831300.518903.073202.10870K562ATP5C1
KLHL17ENSG00000187961.9598.82680347.465800.785206.270004.80050K562BCLAF1
KLHL17ENSG00000187961.9220.15490333.79460-0.600403.201202.26170K562BOP1
KLHL17ENSG00000187961.9561.38630263.604801.0905013.8941011.32860K562CSTF2
KLHL17ENSG00000187961.9977.203801521.83090-0.639103.755502.61320K562CELF1
KLHL17ENSG00000187961.9756.89930587.915700.364403.234801.79260K562DDX6
KLHL17ENSG00000187961.9534.35120247.300001.111404.213403.06990K562EFTUD2
KLHL17ENSG00000187961.9699.95700545.601900.359303.108501.86520K562EIF4B
KLHL17ENSG00000187961.9928.774501237.16210-0.413602.143701.31090K562EIF4G2
KLHL17ENSG00000187961.9222.83760420.97400-0.917702.453701.40310K562FKBP4
KLHL17ENSG00000187961.9209.25710361.13830-0.787305.499104.28480K562FMR1
KLHL17ENSG00000187961.910.59830103.37740-3.2860015.6353013.63290K562G3BP2
KLHL17ENSG00000187961.9874.01510502.919500.797203.768502.27200K562HNRNPA2B1
KLHL17ENSG00000187961.9154.75930483.93610-1.644807.020406.11100K562HNRNPC
KLHL17ENSG00000187961.9619.74040210.068301.560703.943502.62890K562IGF2BP2
KLHL17ENSG00000187961.9346.13060213.631500.696105.077703.37310K562IGF2BP3
KLHL17ENSG00000187961.9374.30330663.32780-0.825504.576702.71080K562ILF2
KLHL17ENSG00000187961.91028.15050697.600000.559502.944502.09060K562KIF1C
KLHL17ENSG00000187961.9471.36450220.683601.0948012.7373010.83570K562MAGOH
KLHL17ENSG00000187961.91474.12880781.499700.9154016.3627013.91910K562MBNL1
KLHL17ENSG00000187961.9743.010901318.58650-0.827503.702102.39300K562MSI2
KLHL17ENSG00000187961.9872.49510547.781900.671405.089703.77120K562NAA15
KLHL17ENSG00000187961.9440.15340697.72610-0.664703.292501.92630K562PABPC1
KLHL17ENSG00000187961.91001.65540439.924101.187007.577105.65880K562PABPN1
KLHL17ENSG00000187961.9320.30110215.760000.569903.539702.00140K562PCBP1
KLHL17ENSG00000187961.9470.52420196.337401.260806.691505.14900K562PCBP2
KLHL17ENSG00000187961.9327.79870597.83300-0.866904.320003.27940K562PCBP3
KLHL17ENSG00000187961.9262.44070458.53110-0.805007.177005.90120K562POLR2G
KLHL17ENSG00000187961.9576.82880378.895500.606204.715603.60320K562PPIG
KLHL17ENSG00000187961.9902.79470523.032600.787403.360101.69270K562PPP1R8
KLHL17ENSG00000187961.9669.15760433.965100.624703.743102.66920K562PSIP1
KLHL17ENSG00000187961.9406.61850214.414700.923209.273508.10540K562PTBP1
KLHL17ENSG00000187961.9756.954601349.75230-0.834402.911102.07460K562PUF60
KLHL17ENSG00000187961.9893.314501436.27570-0.685103.570302.34840K562PUM1
KLHL17ENSG00000187961.91600.92620651.808301.2963027.7031025.96920K562PUS1
KLHL17ENSG00000187961.931.2799098.63740-1.656902.708101.31120K562RAVER1
KLHL17ENSG00000187961.91493.04250635.227801.2328026.2639024.35910K562RBM15
KLHL17ENSG00000187961.9426.89890205.549001.054304.480103.37990K562RBM22
KLHL17ENSG00000187961.91000.95920541.227500.887004.037102.08040K562RBM39
KLHL17ENSG00000187961.9427.64980648.02270-0.599603.047801.38030K562RPS3A
KLHL17ENSG00000187961.9280.50650422.45630-0.590803.628601.96410K562SDAD1
KLHL17ENSG00000187961.91128.50930402.328701.487909.780107.10260K562SF1
KLHL17ENSG00000187961.9681.53170885.66900-0.378003.799902.85270K562SF3A3
KLHL17ENSG00000187961.9322.83180107.507601.5862019.1561016.71560K562SF3B4
KLHL17ENSG00000187961.9883.94000490.493500.849603.793602.17180K562SFPQ
KLHL17ENSG00000187961.9860.73000462.039200.897404.091602.49300K562SNRNP200
KLHL17ENSG00000187961.9402.85710210.208000.938408.585007.34350K562SRSF1
KLHL17ENSG00000187961.9305.25540184.091600.729504.172202.83960K562SRSF4
KLHL17ENSG00000187961.9390.64110198.550500.976208.922706.93880K562SRSF5
KLHL17ENSG00000187961.926.11560101.47820-1.958207.233404.37160K562TAF15
KLHL17ENSG00000187961.9656.14980212.722401.6250015.5898013.64600K562TARDBP
KLHL17ENSG00000187961.958.17060107.76810-0.889602.946901.30480K562TBRG4
KLHL17ENSG00000187961.9561.41830205.200501.451906.787905.41910K562TIA1
KLHL17ENSG00000187961.9490.03010201.414201.282606.076804.31030K562TRA2A
KLHL17ENSG00000187961.9675.76300443.748100.606702.925401.94770K562TRIM56
KLHL17ENSG00000187961.9725.07420951.70160-0.392404.560503.66190K562UPF1
KLHL17ENSG00000187961.9404.52960572.82850-0.501902.979601.72920K562UTP3
KLHL17ENSG00000187961.9618.38830814.34040-0.397103.220302.28050K562WDR3
KLHL17ENSG00000187961.9636.52110846.82370-0.411904.818203.72920K562WDR43
KLHL17ENSG00000187961.9768.639201148.10120-0.578906.420205.01930K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KLHL17 is not available on ENCORE database.





3 RBPs can affect the splicing of KLHL17 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSKLHL17ENSG00000187961.9chr1+8997098999108997288999108994868995470.070000.007390.04073longerK562AQR
A5SSKLHL17ENSG00000187961.9chr1+8987168989338987168988848992998993880.133000.002890.09092longerK562PUS1
A5SSKLHL17ENSG00000187961.9chr1+897008897130897008897109897205897427-0.138000.002220.03679shorterK562AQR
A5SSKLHL17ENSG00000187961.9chr1+899486899560899486899547899709899910-0.081000.003960.05983shorterK562AQR
A5SSKLHL17ENSG00000187961.9chr1+898716898933898716898884899299899388-0.315000.000490.06227shorterK562SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KLHL17 is not avaliable on ENCORE database.