KLHDC2

General Information

Gene Name       : KLHDC2
Gene ID             : ENSG00000165516.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: KLHDC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KLHDC2ENSG00000165516.1011.3516.6414.00ENCSR000AEF
HepG2KLHDC2ENSG00000165516.1045.4754.9350.20ENCSR985KAT
K562KLHDC2ENSG00000165516.1011.3913.4612.43ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KLHDC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • KLHDC2 RNA is bound by 14 proteins.  







eCLIP assay for KLHDC2 is not avaliable on ENCORE database.





14 proteins are bound to KLHDC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr145024746550247484+3'-UTR,CDS,intron-Distal3.056609.80919HepG2BCLAF1
chr145024971050249835+3'-UTR4.922156.93450HepG2ZC3H11A
chr145024693050246944+3'-UTR,CDS,intron-Proximal3.313734.09741HepG2PPIG
chr145024699950247041+3'-UTR,CDS,intron-Proximal5.412707.60796HepG2PPIG
chr145024703550247040+3'-UTR,CDS3.274659.80919HepG2BCLAF1
chr145024643850246529+3'-UTR,CDS,intron-Proximal4.4806030.28258HepG2EFTUD2
chr145024637050246440+3'-UTR,CDS,intron-Proximal4.2147218.70141HepG2PRPF8
chr145024912750249177+3'-UTR,CDS,intron-Distal,intron-Proximal3.564366.58818HepG2PPIG
chr145024648950246528+3'-UTR,CDS,intron-Proximal4.673689.41951HepG2PPIG
chr145024916850249175+3'-UTR,CDS,intron-Proximal4.7707513.32408HepG2BCLAF1
chr145024741950247454+3'-UTR,CDS,intron-Distal,intron-Proximal3.5357316.67182HepG2BCLAF1
chr145024638250246438+3'-UTR,CDS,intron-Proximal3.532698.63702HepG2EFTUD2
chr145024746850247494+3'-UTR,CDS,intron-Distal,intron-Proximal4.523904.16554HepG2PPIG
chr145024741950247490+3'-UTR,CDS,intron-Distal,intron-Proximal3.208786.73433HepG2GRWD1
chr145024912650249168+3'-UTR,CDS,intron-Distal,intron-Proximal4.4423522.01248HepG2BCLAF1
chr145024975250249850+3'-UTR,polyA_signal3.077513.07984HepG2FUBP3
chr145024925950249277+3'-UTR,CDS,intron-Distal,intron-Proximal3.935828.49795HepG2BCLAF1
chr145024928950249306+3'-UTR,CDS,intron-Distal4.215076.65960HepG2BCLAF1
chr145024640650246492+3'-UTR,CDS,intron-Proximal4.069889.14335K562EFTUD2
chr145024908750249108+3'-UTR,CDS,intron-Distal,intron-Proximal3.213439.93919HepG2BCLAF1
chr145024649250246554+3'-UTR,CDS,intron-Proximal3.550818.80518K562EFTUD2
chr145024700350247035+3'-UTR,CDS3.1485514.29752HepG2BCLAF1
chr145024700350247035+3'-UTR,CDS3.770303.49192HepG2UCHL5
chr145024748450247493+3'-UTR,CDS,intron-Distal3.049645.60276HepG2BCLAF1
chr145024973550249832+3'-UTR3.749423.81620HepG2LARP4
chr145024908750249113+3'-UTR,CDS,intron-Distal,intron-Proximal4.698994.84481HepG2PPIG
chr145024742050247455+3'-UTR,CDS,intron-Distal,intron-Proximal5.178496.91190HepG2PPIG
chr145023496850235055+5'-UTR5.7186537.27906HepG2DDX3X
chr145023488550234968+5'-UTR4.3216423.92760HepG2DDX3X
chr145023512350235182+5'-UTR3.298384.45364HepG2RBM15
chr145023512950235205+5'-UTR,CDS3.590364.57478HepG2DDX52
chr145024490550244949+CDS3.8865215.27481HepG2BCLAF1
chr145024128150241325+CDS3.492518.43905HepG2PPIG
chr145024127650241381+CDS,intron-Proximal3.740006.80697HepG2ZNF800
chr145024631350246376+CDS3.977528.58713HepG2PPIG
chr145023833850238389+CDS4.3053513.42460HepG2BCLAF1
chr145024494250244995+CDS,intron-Proximal3.972744.75655HepG2PRPF8
chr145024461450244657+CDS3.360357.33138HepG2BCLAF1
chr145023833850238387+CDS3.591136.98305HepG2PPIG
chr145023835150238391+CDS4.582244.40915HepG2ZNF800
chr145024516950245212+CDS3.149027.01796HepG2BCLAF1
chr145024635350246411+CDS,intron-Proximal4.221039.94686HepG2GRWD1
chr145024130450241383+CDS3.1633914.97798HepG2BCLAF1
chr145023533550235383+CDS,intron-Proximal5.334998.60090HepG2PRPF8
chr145024491450244974+CDS3.708744.25269HepG2ZNF800
chr145024496850244977+CDS4.9022711.09109HepG2BCLAF1
chr145024494950244968+CDS4.6691114.65888HepG2BCLAF1
chr145024512950245161+CDS4.5749510.68105HepG2BCLAF1
chr145024143250241582+intron-Distal,intron-Proximal4.447164.83283HepG2KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KLHDC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KLHDC2 is not available on ENCORE database.

  • 107 RBPs can affect the levels of KLHDC2.  








The Knockdown/knockout RNA-Seq assay for KLHDC2 is not available on ENCORE database.





107 RBPs can affect the gene expression of KLHDC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KLHDC2ENSG00000165516.61772.522801386.465900.354302.530001.62810HepG2ABCF1
KLHDC2ENSG00000165516.6706.144501447.08510-1.0351029.8461028.35650HepG2ACO1
KLHDC2ENSG00000165516.61231.446003009.32310-1.2891022.7874021.42490HepG2AKAP1
KLHDC2ENSG00000165516.61961.543302489.99140-0.344202.572101.81290HepG2ASCC1
KLHDC2ENSG00000165516.6948.231201412.83780-0.575304.224903.00640HepG2CCAR1
KLHDC2ENSG00000165516.61042.359101446.56950-0.472808.980307.91300HepG2CKAP4
KLHDC2ENSG00000165516.61218.25800989.877800.299402.840201.80850HepG2YBX3
KLHDC2ENSG00000165516.61209.941001870.81880-0.6287012.9569011.76540HepG2CELF1
KLHDC2ENSG00000165516.62337.378102011.594400.216503.040302.26910HepG2DAZAP1
KLHDC2ENSG00000165516.61892.841301266.308300.579808.470306.88770HepG2DDX24
KLHDC2ENSG00000165516.62363.368202882.76650-0.286601.878901.35300HepG2DDX3X
KLHDC2ENSG00000165516.6574.52030999.23020-0.798507.373606.18120HepG2DDX55
KLHDC2ENSG00000165516.61703.542902476.20850-0.539604.781803.98950HepG2DDX6
KLHDC2ENSG00000165516.61339.27980937.477600.514505.497204.14230HepG2DHX30
KLHDC2ENSG00000165516.62691.228101384.416300.9589033.3335031.65620HepG2DKC1
KLHDC2ENSG00000165516.61513.00070971.982600.6383011.7236010.35740HepG2DNAJC21
KLHDC2ENSG00000165516.6666.11770929.14860-0.480103.698402.40660HepG2EFTUD2
KLHDC2ENSG00000165516.61859.802402380.58580-0.356202.667902.08610HepG2EIF2S1
KLHDC2ENSG00000165516.6644.98160904.75960-0.488303.625202.59790HepG2EIF3D
KLHDC2ENSG00000165516.61648.025201221.956900.431404.928803.53620HepG2EIF3G
KLHDC2ENSG00000165516.61840.091102630.89790-0.515804.364303.56570HepG2EIF4A3
KLHDC2ENSG00000165516.61686.562302561.41320-0.602904.661703.78290HepG2EIF4B
KLHDC2ENSG00000165516.62521.044301984.557100.345105.621504.50050HepG2EIF4G1
KLHDC2ENSG00000165516.61605.111701201.088600.418203.801202.53280HepG2ESF1
KLHDC2ENSG00000165516.62235.847902666.55190-0.254203.139702.50580HepG2ETF1
KLHDC2ENSG00000165516.6765.505901400.01620-0.871009.660108.33760HepG2FIP1L1
KLHDC2ENSG00000165516.61126.426701519.70500-0.432002.438701.38680HepG2FUS
KLHDC2ENSG00000165516.61533.142602654.25140-0.7918011.073109.77990HepG2FXR1
KLHDC2ENSG00000165516.62001.730802462.32010-0.298801.877601.32380HepG2G3BP1
KLHDC2ENSG00000165516.61084.552501388.63630-0.356602.209601.30440HepG2GNB2L1
KLHDC2ENSG00000165516.61224.57770699.761900.807208.639107.55010HepG2GPKOW
KLHDC2ENSG00000165516.61455.42660981.294500.568606.693105.75420HepG2HNRNPA1
KLHDC2ENSG00000165516.61430.982701091.510300.390603.369302.61050HepG2HNRNPC
KLHDC2ENSG00000165516.61243.45210903.511500.460603.356802.57260HepG2HNRNPF
KLHDC2ENSG00000165516.61619.971902493.05900-0.621908.148106.99730HepG2HNRNPK
KLHDC2ENSG00000165516.61091.68180667.796900.709007.443006.46930HepG2HNRNPLL
KLHDC2ENSG00000165516.6681.03140966.00210-0.504304.824203.60770HepG2HNRNPM
KLHDC2ENSG00000165516.61397.16780889.693000.651009.257108.00310HepG2IGF2BP1
KLHDC2ENSG00000165516.61579.229701322.692100.255603.350502.22830HepG2KIF1C
KLHDC2ENSG00000165516.61071.147201360.25540-0.344702.381201.33420HepG2LARP7
KLHDC2ENSG00000165516.62006.380502655.17710-0.404203.279402.56540HepG2MAGOH
KLHDC2ENSG00000165516.61464.362302670.07270-0.8666011.3302010.11710HepG2MATR3
KLHDC2ENSG00000165516.6650.90330946.92530-0.540802.462101.46730HepG2METAP2
KLHDC2ENSG00000165516.6705.679001133.16260-0.683308.501307.15240HepG2MSI2
KLHDC2ENSG00000165516.61137.45150681.096500.739804.995703.66910HepG2MTPAP
KLHDC2ENSG00000165516.61581.110702732.99620-0.7895010.363409.17840HepG2NCBP2
KLHDC2ENSG00000165516.61326.51280592.139801.1635020.2256018.44550HepG2NSUN2
KLHDC2ENSG00000165516.61005.548401694.54480-0.752904.899903.69040HepG2PABPC1
KLHDC2ENSG00000165516.61470.490302434.04150-0.727109.003007.71980HepG2PABPC4
KLHDC2ENSG00000165516.6623.768901073.26320-0.7829015.1510013.44540HepG2PARN
KLHDC2ENSG00000165516.61487.167202466.26030-0.7298010.469709.41150HepG2PCBP1
KLHDC2ENSG00000165516.61292.37900967.103100.418205.192404.21140HepG2PPIL4
KLHDC2ENSG00000165516.6499.90180936.84710-0.9062017.7164016.03830HepG2PRPF4
KLHDC2ENSG00000165516.6452.38530770.85050-0.768906.942305.72990HepG2PRPF8
KLHDC2ENSG00000165516.61299.358002509.36410-0.9495017.6688016.51540HepG2PTBP1
KLHDC2ENSG00000165516.61520.257602021.29220-0.411008.777007.84640HepG2PUM1
KLHDC2ENSG00000165516.61678.253402019.81680-0.267302.484801.84920HepG2PUM2
KLHDC2ENSG00000165516.61747.692301473.920600.245702.994702.36060HepG2PUS1
KLHDC2ENSG00000165516.61987.853202718.01860-0.451305.383104.55380HepG2QKI
KLHDC2ENSG00000165516.6562.580101388.33970-1.3032012.0122010.62100HepG2RAVER1
KLHDC2ENSG00000165516.6765.026702228.77070-1.5427058.8904057.11590HepG2RBM22
KLHDC2ENSG00000165516.61912.811002466.65740-0.366903.183302.46480HepG2RBM25
KLHDC2ENSG00000165516.62306.659102792.80420-0.275902.760502.21980HepG2NELFE
KLHDC2ENSG00000165516.62209.500102600.89460-0.235302.270501.70560HepG2RECQL
KLHDC2ENSG00000165516.61578.96200973.420400.697709.012607.88980HepG2RPLP0
KLHDC2ENSG00000165516.62210.493701363.724800.696705.276403.99590HepG2RPS10
KLHDC2ENSG00000165516.6576.86070880.35680-0.609906.353705.46330HepG2RPS19
KLHDC2ENSG00000165516.61169.810701544.14590-0.400502.896201.79380HepG2RPS5
KLHDC2ENSG00000165516.6577.50650762.53320-0.401002.138901.44010HepG2RRP9
KLHDC2ENSG00000165516.6882.197801633.47360-0.888808.737507.48340HepG2SF3A3
KLHDC2ENSG00000165516.61640.244702612.83720-0.671709.815508.80230HepG2SF3B4
KLHDC2ENSG00000165516.62082.067901825.738500.189402.296101.64760HepG2SLBP
KLHDC2ENSG00000165516.6701.928901126.06350-0.6819014.7741013.47210HepG2SMN1
KLHDC2ENSG00000165516.6922.945501415.43970-0.616904.602803.34130HepG2SMNDC1
KLHDC2ENSG00000165516.61685.18530735.457901.1961012.8900011.21960HepG2SNRNP70
KLHDC2ENSG00000165516.61741.453702517.36180-0.5316011.4459010.61510HepG2SRFBP1
KLHDC2ENSG00000165516.61761.080002727.12810-0.630909.028008.28350HepG2SRSF1
KLHDC2ENSG00000165516.61510.555101880.02650-0.315704.207103.46410HepG2SRSF5
KLHDC2ENSG00000165516.63388.803902185.748500.6325020.5840019.46550HepG2SSB
KLHDC2ENSG00000165516.61398.866602138.10980-0.6121016.5010015.18550HepG2SUCLG1
KLHDC2ENSG00000165516.6824.51800650.932200.340902.143501.49360HepG2TARDBP
KLHDC2ENSG00000165516.6790.450101063.01270-0.427405.616004.86500HepG2TRIM56
KLHDC2ENSG00000165516.6733.004101197.66900-0.708307.441206.41770HepG2U2AF1
KLHDC2ENSG00000165516.6533.236601035.49220-0.957502.879101.87090HepG2U2AF2
KLHDC2ENSG00000165516.61548.474401969.02160-0.346602.339501.57470HepG2UBE2L3
KLHDC2ENSG00000165516.61082.064401448.64110-0.420906.684905.67570HepG2UPF1
KLHDC2ENSG00000165516.61446.95230910.883300.667605.227603.82490HepG2UPF2
KLHDC2ENSG00000165516.6540.017801398.60650-1.3729046.4934044.48580HepG2UTP3
KLHDC2ENSG00000165516.6970.145501526.78110-0.654204.923703.53410HepG2XRCC6
KLHDC2ENSG00000165516.61921.64000979.198000.9726014.8751013.22350HepG2XRN2
KLHDC2ENSG00000165516.61264.06660924.504600.451207.482606.46690HepG2ZC3H8
KLHDC2ENSG00000165516.6876.900301593.22830-0.8615028.6006027.31520HepG2ZNF622
KLHDC2ENSG00000165516.6926.78730727.211100.349803.015602.06320K562ATP5C1
KLHDC2ENSG00000165516.6341.97870245.914100.475702.190701.42090K562BOP1
KLHDC2ENSG00000165516.6585.30890393.072700.574302.659001.62350K562CNOT7
KLHDC2ENSG00000165516.6665.97320516.714000.366002.662801.63990K562DDX3X
KLHDC2ENSG00000165516.6199.01020310.89670-0.643603.632002.57490K562EFTUD2
KLHDC2ENSG00000165516.6349.44930465.74770-0.414502.674701.89030K562EIF3G
KLHDC2ENSG00000165516.6421.80850539.85470-0.356002.009101.30660K562EIF4A3
KLHDC2ENSG00000165516.6364.42950266.065500.453802.453601.65650K562FIP1L1
KLHDC2ENSG00000165516.6314.71600561.42900-0.8351010.027108.96010K562FXR1
KLHDC2ENSG00000165516.6772.06230543.468900.506402.967502.23300K562G3BP2
KLHDC2ENSG00000165516.6479.16030347.371700.463903.518902.23420K562GLRX3
KLHDC2ENSG00000165516.6391.96100249.661100.650604.258903.27880K562GPKOW
KLHDC2ENSG00000165516.6393.46680288.023800.450002.382401.82220K562HNRNPC
KLHDC2ENSG00000165516.6390.88210561.29550-0.522003.351801.97540K562HNRNPK
KLHDC2ENSG00000165516.6721.84230545.164100.404903.468402.46940K562HNRNPU
KLHDC2ENSG00000165516.6639.03070360.703700.825008.198006.84260K562HSPD1
KLHDC2ENSG00000165516.6910.24380735.451300.307502.397801.63830K562KIF1C
KLHDC2ENSG00000165516.6396.45480590.55740-0.574904.075603.05020K562MAGOH
KLHDC2ENSG00000165516.6506.18630405.764400.318902.316601.62790K562NSUN2
KLHDC2ENSG00000165516.6270.09980525.49740-0.960209.992008.08740K562PCBP2
KLHDC2ENSG00000165516.6567.61650344.222500.721505.435404.26300K562PCBP3
KLHDC2ENSG00000165516.6417.21420264.027700.660005.211604.11140K562POLR2G
KLHDC2ENSG00000165516.6457.47910302.062300.598804.186803.14930K562PPIG
KLHDC2ENSG00000165516.6175.17340302.53860-0.788304.540603.57980K562PRPF8
KLHDC2ENSG00000165516.6314.60380573.74400-0.866907.794506.71880K562PTBP1
KLHDC2ENSG00000165516.6269.40070550.29430-1.0304012.0683010.13480K562RBM22
KLHDC2ENSG00000165516.6428.13200579.06350-0.435702.737001.65100K562NELFE
KLHDC2ENSG00000165516.6466.66440309.321800.593203.037901.64170K562RRP9
KLHDC2ENSG00000165516.6388.89920565.13380-0.539204.751803.62020K562SF3B4
KLHDC2ENSG00000165516.6386.85430562.43120-0.539904.288003.41300K562SRSF1
KLHDC2ENSG00000165516.6484.62750349.069000.473302.788001.42360K562SSRP1
KLHDC2ENSG00000165516.6441.63100319.252100.468002.550901.35480K562STAU1
KLHDC2ENSG00000165516.6589.67300430.242900.454703.065902.31100K562UPF1
KLHDC2ENSG00000165516.6536.55230368.141500.543404.364403.25570K562WDR3
KLHDC2ENSG00000165516.6471.57540382.850300.300602.040301.30570K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KLHDC2 is not available on ENCORE database.





20 RBPs can affect the splicing of KLHDC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKLHDC2ENSG00000165516.6chr14+502464655024652450246312502463935024693050247040-0.080000.000920.07626excludedHepG2PRPF8
SEKLHDC2ENSG00000165516.6chr14+502464655024652450246312502463935024693050247040-0.058000.000230.00944excludedHepG2SF3A3
A5SSKLHDC2ENSG00000165516.6chr14+502463125024652450246312502463935024693050247040-0.078000.000320.03028shorterHepG2SF3A3
RIKLHDC2ENSG00000165516.6chr14+502463125024652450246312502463935024646550246524-0.104000.000020.00200excludedHepG2AKAP1
RIKLHDC2ENSG00000165516.6chr14+5024631250246524502463125024639350246465502465240.180000.000360.00953includedHepG2PCBP2
RIKLHDC2ENSG00000165516.6chr14+5024631250246524502463125024639350246465502465240.115000.002090.01449includedK562PUS1
RIKLHDC2ENSG00000165516.6chr14+502463125024652450246312502463935024646550246524-0.081000.000330.02907excludedHepG2DDX3X
RIKLHDC2ENSG00000165516.6chr14+5024631250246524502463125024639350246465502465240.155000.003610.07191includedHepG2UCHL5
RIKLHDC2ENSG00000165516.6chr14+5024631250246524502463125024639350246465502465240.098000.003830.09299includedHepG2MATR3
RIKLHDC2ENSG00000165516.6chr14+502463125024652450246312502463935024646550246524-0.214000.000250.00826excludedK562RBM22
RIKLHDC2ENSG00000165516.6chr14+5024631250246524502463125024639350246465502465240.148000.001120.01407includedK562RBM15
RIKLHDC2ENSG00000165516.6chr14+502463125024652450246312502463935024646550246524-0.140000.000070.00636excludedHepG2HNRNPC
RIKLHDC2ENSG00000165516.6chr14+502463125024652450246312502463935024646550246524-0.132000.001230.02417excludedHepG2TIAL1
RIKLHDC2ENSG00000165516.6chr14+502463125024652450246312502463935024646550246524-0.122000.001440.06852excludedHepG2HNRNPU
RIKLHDC2ENSG00000165516.6chr14+5024631250246524502463125024639350246465502465240.117000.000410.00445includedHepG2SF3B4
RIKLHDC2ENSG00000165516.6chr14+5024631250246524502463125024639350246465502465240.148000.000080.00246includedHepG2FUBP3
RIKLHDC2ENSG00000165516.6chr14+502463125024652450246312502463935024646550246524-0.132000.000110.00193excludedHepG2RBM22
RIKLHDC2ENSG00000165516.6chr14+5024631250246524502463125024639350246465502465240.097000.002210.03472includedHepG2SRSF9
RIKLHDC2ENSG00000165516.6chr14+5024631250246524502463125024639350246465502465240.173000.000000.00001includedHepG2HNRNPK
RIKLHDC2ENSG00000165516.6chr14+5024631250246524502463125024639350246465502465240.171000.000360.00600includedK562UTP18
RIKLHDC2ENSG00000165516.6chr14+5024631250246524502463125024639350246465502465240.126000.000050.00769includedHepG2SSB
RIKLHDC2ENSG00000165516.6chr14+502463125024652450246312502463935024646550246524-0.176000.001570.03063excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KLHDC2 is not avaliable on ENCORE database.