ITM2C

General Information

Gene Name       : ITM2C
Gene ID             : ENSG00000135916.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ITM2C)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ITM2CENSG00000135916.1552.35115.9284.14ENCSR000AEF
HepG2ITM2CENSG00000135916.15157.0690.34123.70ENCSR985KAT
K562ITM2CENSG00000135916.1527.0925.7826.44ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ITM2C is not avaliable on ENCORE database.



Proteins bound to RNA
  • ITM2C RNA is bound by 22 proteins.  







eCLIP assay for ITM2C is not avaliable on ENCORE database.





22 proteins are bound to ITM2C RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2231743130231743246+3'-UTR6.1920938.52695HepG2AKAP1
chr2231743794231743862+3'-UTR3.5323310.52047K562TIA1
chr2231743523231743653+3'-UTR4.3638615.61943K562UPF1
chr2231743243231743298+3'-UTR3.767308.45303HepG2DDX55
chr2231743162231743236+3'-UTR6.3248617.30102K562UPF1
chr2231743111231743224+3'-UTR4.5729931.33435HepG2GRSF1
chr2231738191231738236+3'-UTR,CDS,intron-Distal4.7602028.84780HepG2DDX3X
chr2231743145231743251+3'-UTR3.052006.74172HepG2PRPF4
chr2231743125231743238+3'-UTR7.0232769.33423HepG2UPF1
chr2231738131231738147+3'-UTR,CDS,intron-Distal,intron-Proximal4.4643111.79106HepG2DDX3X
chr2231743045231743125+3'-UTR6.4631545.08697HepG2UPF1
chr2231743338231743390+3'-UTR5.8114415.84284HepG2LIN28B
chr2231743226231743325+3'-UTR3.4012515.86461HepG2LARP4
chr2231742999231743042+3'-UTR3.858017.06377K562YBX3
chr2231743246231743329+3'-UTR5.3235629.27450HepG2AKAP1
chr2231743903231743943+3'-UTR5.870068.95391K562PABPC4
chr2231743449231743612+3'-UTR6.6624979.12178HepG2UPF1
chr2231743668231743721+3'-UTR5.271968.40676K562UPF1
chr2231743051231743114+3'-UTR5.4926224.72026HepG2AKAP1
chr2231743292231743343+3'-UTR4.4689511.39836K562UPF1
chr2231743797231743894+3'-UTR4.8777420.74890K562PUM2
chr2231743153231743232+3'-UTR3.433476.02117HepG2FAM120A
chr2231743695231743865+3'-UTR3.229695.78778K562IGF2BP1
chr2231743736231743784+3'-UTR3.688493.27788HepG2IGF2BP3
chr2231743243231743333+3'-UTR5.2216934.55027HepG2UPF1
chr2231743777231743851+3'-UTR3.743404.02483HepG2TIA1
chr2231743236231743348+3'-UTR3.646508.53392K562FAM120A
chr2231742906231742974+3'-UTR4.5811723.59145HepG2AKAP1
chr2231742851231742902+3'-UTR5.710087.30415HepG2PCBP1
chr2231743471231743511+3'-UTR5.6648012.79640HepG2AKAP1
chr2231742975231743003+3'-UTR4.3418918.71521HepG2UPF1
chr2231743062231743096+3'-UTR3.206976.42991HepG2LARP4
chr2231743367231743428+3'-UTR4.6692916.04762HepG2UPF1
chr2231743257231743349+3'-UTR3.241869.11368HepG2GRSF1
chr2231743758231743859+3'-UTR4.2656615.39446K562UPF1
chr2231743353231743401+3'-UTR5.4628210.18755K562UPF1
chr2231743168231743236+3'-UTR4.248576.53861K562FAM120A
chr2231743792231743857+3'-UTR4.1280315.76533HepG2AKAP1
chr2231742857231742907+3'-UTR4.1137414.32964HepG2UPF1
chr2231743049231743111+3'-UTR3.330956.32251K562UPF1
chr2231738130231738164+3'-UTR,CDS,intron-Distal,intron-Proximal4.556576.05571HepG2RPS3
chr2231743003231743045+3'-UTR4.1255516.12298HepG2UPF1
chr2231743899231743944+3'-UTR6.6702227.30365K562PUM2
chr2231743522231743606+3'-UTR4.5308516.69193HepG2AKAP1
chr2231743061231743111+3'-UTR3.244817.04416HepG2GRSF1
chr2231743806231743864+3'-UTR3.972705.32645HepG2RBFOX2
chr2231738184231738239+3'-UTR,CDS,intron-Distal5.0340310.51120HepG2RPS3
chr2231743401231743449+3'-UTR4.413858.17454K562UPF1
chr2231742915231742975+3'-UTR4.8176028.47524HepG2UPF1
chr2231742853231742906+3'-UTR4.2327014.48103HepG2AKAP1
chr2231742974231743022+3'-UTR4.5868011.34140HepG2AKAP1
chr2231743897231743943+3'-UTR3.115663.13224HepG2ZC3H11A
chr2231729670231729744+5'-UTR,CDS,intron-Distal3.167305.35667HepG2EIF3D
chr2231729667231729749+5'-UTR,CDS,intron-Distal5.0179087.35887HepG2DDX3X
chr2231729692231729745+5'-UTR,CDS,intron-Distal4.118923.86664K562DDX3X
chr2231729674231729733+5'-UTR,intron-Distal3.600917.86100HepG2RPS3
chr2231729959231730018+5'-UTR,intron-Distal,intron-Proximal3.266903.46580HepG2CSTF2T
chr2231741617231741683+CDS,intron-Distal,intron-Proximal4.063596.77664K562SND1
chr2231742189231742264+CDS4.2526317.27732HepG2SND1
chr2231729787231729837+CDS,intron-Distal4.6490042.26360HepG2DDX3X
chr2231729745231729796+CDS,intron-Distal4.363854.26442K562DDX3X
chr2231729837231729861+CDS,intron-Distal,intron-Proximal4.6015827.06936HepG2DDX3X
chr2231742182231742253+CDS3.274683.49838K562SND1
chr2231742113231742189+CDS,intron-Proximal4.5985719.86223HepG2SND1
chr2231740448231740524+CDS,intron-Proximal3.909535.28152K562SND1
chr2231741571231741617+CDS,intron-Distal,intron-Proximal4.403974.89631K562SND1
chr2231729749231729787+CDS,intron-Distal4.6263236.17073HepG2DDX3X
chr2231740506231740523+CDS3.530499.12580HepG2SND1
chr2231741606231741677+CDS,intron-Distal3.663589.26008K562YBX3
chr2231742166231742249+CDS3.6184814.11284HepG2LIN28B
chr2231742120231742166+CDS4.0090810.90137HepG2LIN28B
chr2231742114231742153+CDS,intron-Proximal4.210453.60906K562SND1
chr2231741633231741683+CDS,intron-Distal,intron-Proximal3.560077.82734HepG2SND1
chr2231740351231740412+CDS4.706357.38299HepG2RPS3
chr2231740338231740366+CDS3.076883.69775K562YBX3
chr2231742750231742806+CDS3.099083.67697K562YBX3
chr2231742120231742228+CDS3.639035.38431K562LIN28B
chr2231741571231741594+CDS,intron-Distal,intron-Proximal3.228456.50171HepG2SND1
chr2231730634231730677+intron-Distal3.974413.63902HepG2CSTF2T
chr2231729870231729940+intron-Distal,intron-Proximal4.730456.05659HepG2CSTF2T
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ITM2C is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ITM2C is not available on ENCORE database.

  • 108 RBPs can affect the levels of ITM2C.  








The Knockdown/knockout RNA-Seq assay for ITM2C is not available on ENCORE database.





108 RBPs can affect the gene expression of ITM2C :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ITM2CENSG00000135916.113564.225802806.829600.344507.261506.37310HepG2ACO1
ITM2CENSG00000135916.117384.014105096.533700.534805.179504.48060HepG2AKAP1
ITM2CENSG00000135916.115345.539404216.833500.342102.829502.03760HepG2ASCC1
ITM2CENSG00000135916.114754.148104078.590600.221003.124202.40140HepG2AUH
ITM2CENSG00000135916.113492.445702203.827200.6641010.673409.59710HepG2BOP1
ITM2CENSG00000135916.113388.229902806.090600.271905.201404.34090HepG2CKAP4
ITM2CENSG00000135916.113139.571602023.247000.633808.854907.68640HepG2CPSF6
ITM2CENSG00000135916.113284.113902695.329500.284902.479601.43390HepG2CPSF7
ITM2CENSG00000135916.111477.910402196.71810-0.571804.326902.49200HepG2CSTF2T
ITM2CENSG00000135916.115295.953303335.453000.6669021.9428020.48620HepG2CELF1
ITM2CENSG00000135916.112394.733603585.73370-0.582407.577406.44040HepG2DAZAP1
ITM2CENSG00000135916.111863.091802315.57180-0.313703.057502.09730HepG2DDX24
ITM2CENSG00000135916.117178.222604194.205400.7751010.213409.10790HepG2DDX6
ITM2CENSG00000135916.112313.618902685.34200-0.215002.585601.92810HepG2DKC1
ITM2CENSG00000135916.112675.080002219.595200.269202.324201.67350HepG2DNAJC21
ITM2CENSG00000135916.112764.182802200.049800.329206.839605.87970HepG2DNAJC2
ITM2CENSG00000135916.115342.244604031.388400.406103.731103.04970HepG2EIF2S1
ITM2CENSG00000135916.112205.623903538.14710-0.681809.317507.95430HepG2EIF4G1
ITM2CENSG00000135916.116477.017604682.871200.4678012.0424010.93220HepG2ETF1
ITM2CENSG00000135916.112336.403401844.597300.340903.874202.46670HepG2FAM120A
ITM2CENSG00000135916.114580.379003305.383700.470504.127203.20280HepG2FIP1L1
ITM2CENSG00000135916.115590.806204169.916000.422903.670502.90820HepG2G3BP1
ITM2CENSG00000135916.113484.610704427.50710-0.345502.965002.04200HepG2G3BP2
ITM2CENSG00000135916.113303.539002679.640500.301904.854603.59640HepG2HDGF
ITM2CENSG00000135916.113822.422003295.728300.213802.692801.76750HepG2HNRNPA2B1
ITM2CENSG00000135916.113514.688602492.560700.495706.554105.52380HepG2HNRNPC
ITM2CENSG00000135916.113838.311203266.117400.232803.393702.65390HepG2HNRNPL
ITM2CENSG00000135916.112931.405002476.080000.243403.455302.78540HepG2HNRNPU
ITM2CENSG00000135916.113002.425102529.230700.247304.708103.77360HepG2ILF2
ITM2CENSG00000135916.113113.003502565.714000.278805.383303.97360HepG2KIF1C
ITM2CENSG00000135916.112102.240303547.79160-0.755007.528205.50380HepG2KRR1
ITM2CENSG00000135916.116201.845504136.389200.584205.364804.19460HepG2LARP4
ITM2CENSG00000135916.112811.291004497.22960-0.677808.852307.69260HepG2MAGOH
ITM2CENSG00000135916.113285.741204522.25650-0.460804.024803.27610HepG2MATR3
ITM2CENSG00000135916.112672.939804628.66420-0.7922011.149409.92250HepG2NCBP2
ITM2CENSG00000135916.111360.039901940.73540-0.513005.403904.37510HepG2NSUN2
ITM2CENSG00000135916.113266.543604121.59110-0.335402.554701.85760HepG2PABPC4
ITM2CENSG00000135916.113225.105402450.872700.396007.728406.42620HepG2PARN
ITM2CENSG00000135916.113087.591404228.12860-0.4535011.2107010.12260HepG2PCBP1
ITM2CENSG00000135916.112977.745502208.462400.431107.424606.25960HepG2PPIL4
ITM2CENSG00000135916.113223.989904302.24380-0.416209.208408.32670HepG2PTBP1
ITM2CENSG00000135916.114870.343703394.366100.520808.532607.56230HepG2PUF60
ITM2CENSG00000135916.114610.927803603.495700.355606.217605.40250HepG2PUM1
ITM2CENSG00000135916.113638.188604659.51110-0.357002.417901.82770HepG2QKI
ITM2CENSG00000135916.111254.054302227.57530-0.828903.575002.77610HepG2RAVER1
ITM2CENSG00000135916.113525.419504228.77750-0.262402.569901.91660HepG2RBM25
ITM2CENSG00000135916.113848.970904788.01350-0.315005.888405.14630HepG2NELFE
ITM2CENSG00000135916.113472.682904459.33090-0.360807.596006.64860HepG2RECQL
ITM2CENSG00000135916.112373.319602008.164400.240901.954601.43040HepG2RPS19
ITM2CENSG00000135916.111866.564202205.04810-0.240403.299402.60630HepG2SAFB2
ITM2CENSG00000135916.111721.799302166.47040-0.331402.714302.01460HepG2SF3B1
ITM2CENSG00000135916.113636.555104479.25410-0.300705.451004.66890HepG2SF3B4
ITM2CENSG00000135916.113717.635103255.132400.191602.125401.49680HepG2SLBP
ITM2CENSG00000135916.113197.533102276.257100.490202.905801.92310HepG2SMNDC1
ITM2CENSG00000135916.112706.676401490.141000.861002.824901.49900HepG2SNRNP200
ITM2CENSG00000135916.113214.871104420.67210-0.4595013.4170012.53460HepG2SRFBP1
ITM2CENSG00000135916.112978.967204675.34580-0.6503024.1654023.06950HepG2SRSF1
ITM2CENSG00000135916.113977.999503351.713200.247003.261402.59150HepG2SRSF5
ITM2CENSG00000135916.111756.270803838.12350-1.1279060.1289058.51140HepG2SSB
ITM2CENSG00000135916.113157.451602231.557200.500606.804305.37420HepG2SUPT6H
ITM2CENSG00000135916.113085.087004202.31180-0.445908.567607.67040HepG2TAF15
ITM2CENSG00000135916.113102.329602133.273800.540206.895005.82020HepG2TARDBP
ITM2CENSG00000135916.113059.899702427.486400.333905.991205.21790HepG2TRIM56
ITM2CENSG00000135916.114792.492903316.521400.531006.561605.13080HepG2TUFM
ITM2CENSG00000135916.113379.493602407.566900.4891013.0290011.72060HepG2UPF1
ITM2CENSG00000135916.113026.575802647.856900.192802.963802.40380HepG2ZNF622
ITM2CENSG00000135916.111980.641401008.934000.9730032.5753030.71390K562AGGF1
ITM2CENSG00000135916.111608.815801108.739700.537006.601204.92150K562AKAP8
ITM2CENSG00000135916.111767.531901049.859700.751406.340105.32280K562AKAP8L
ITM2CENSG00000135916.111716.713001101.589900.640002.385401.54170K562ATP5C1
ITM2CENSG00000135916.111457.251301205.672600.273302.554901.43190K562CCDC124
ITM2CENSG00000135916.11653.54250445.317400.553304.862703.82760K562CPSF6
ITM2CENSG00000135916.11499.80400386.268500.371702.350901.39120K562CSTF2
ITM2CENSG00000135916.11579.58580837.08640-0.530406.787505.83170K562DDX47
ITM2CENSG00000135916.111012.73810717.946400.496206.167603.95850K562DDX6
ITM2CENSG00000135916.11885.17960642.679200.461805.096204.16270K562EIF2S2
ITM2CENSG00000135916.11538.97880739.82090-0.456903.482402.56570K562EIF4A3
ITM2CENSG00000135916.11840.18670666.258600.334502.905601.71600K562EIF4B
ITM2CENSG00000135916.11854.48610447.567600.9329012.3909010.47970K562FIP1L1
ITM2CENSG00000135916.11651.66200453.185300.523903.841902.82730K562FMR1
ITM2CENSG00000135916.11503.14840769.38430-0.612707.397506.47200K562FXR1
ITM2CENSG00000135916.11790.92130580.932300.445103.681901.99220K562G3BP1
ITM2CENSG00000135916.11162.08820391.42410-1.272006.767605.55360K562G3BP2
ITM2CENSG00000135916.11669.76280425.133200.655605.929504.76990K562GPKOW
ITM2CENSG00000135916.111424.23220856.430400.7337010.468408.97250K562GRSF1
ITM2CENSG00000135916.111233.98860724.528700.768103.483302.06680K562HNRNPA2B1
ITM2CENSG00000135916.11434.31760606.74180-0.482303.022401.73020K562HNRNPK
ITM2CENSG00000135916.111049.34740606.786400.790109.639208.17980K562HSPD1
ITM2CENSG00000135916.11992.73370608.010600.707206.065704.29470K562IGF2BP2
ITM2CENSG00000135916.111708.249301114.100000.616509.240107.49900K562KIF1C
ITM2CENSG00000135916.111602.338901066.519400.587207.738805.58440K562MAK16
ITM2CENSG00000135916.111791.339701248.082300.521204.515603.29490K562MBNL1
ITM2CENSG00000135916.111424.64890874.820900.703406.155604.64260K562NAA15
ITM2CENSG00000135916.111035.55130773.819700.420206.157705.10440K562NSUN2
ITM2CENSG00000135916.111456.89880633.492801.201406.119204.46910K562PABPN1
ITM2CENSG00000135916.11818.40710624.404300.390203.215101.75880K562PCBP1
ITM2CENSG00000135916.111185.74680865.598200.453903.423602.49760K562PCBP3
ITM2CENSG00000135916.11888.96600663.954000.420903.801102.85650K562POLR2G
ITM2CENSG00000135916.11881.09170508.098500.794109.308207.56520K562PPIG
ITM2CENSG00000135916.111510.62440752.892401.004505.168202.99710K562PPP1R8
ITM2CENSG00000135916.11746.68140524.699400.508903.954402.84550K562PSIP1
ITM2CENSG00000135916.112270.938701041.043201.125204.969304.26890K562PUS1
ITM2CENSG00000135916.11596.44030437.626900.446603.290201.32900K562QKI
ITM2CENSG00000135916.111909.553101014.447100.9124023.4045021.60710K562RBM15
ITM2CENSG00000135916.11640.31330478.942800.418803.048202.00260K562RCC2
ITM2CENSG00000135916.111335.70570579.192901.205406.140104.12910K562SF1
ITM2CENSG00000135916.11967.61310763.591000.341503.220502.34390K562SF3A3
ITM2CENSG00000135916.111100.93270665.404700.726302.815401.57620K562SNRNP200
ITM2CENSG00000135916.11679.05010454.001900.580704.687003.25170K562SRFBP1
ITM2CENSG00000135916.11612.91770782.31800-0.352103.342502.32460K562SRPK2
ITM2CENSG00000135916.11764.46630608.293300.329602.210601.57000K562SRSF1
ITM2CENSG00000135916.11830.24320574.603500.530904.618303.20050K562SRSF5
ITM2CENSG00000135916.11535.79200665.94840-0.313702.055301.34630K562SYNCRIP
ITM2CENSG00000135916.11841.52510615.531200.451103.110602.36030K562TARDBP
ITM2CENSG00000135916.11614.77770390.552500.654403.454601.57470K562TFIP11
ITM2CENSG00000135916.11891.16540593.776000.585705.584004.35600K562TIA1
ITM2CENSG00000135916.11821.96490504.646000.703706.294904.82680K562TIAL1
ITM2CENSG00000135916.11881.85650582.910600.597205.227303.63070K562TRA2A
ITM2CENSG00000135916.11810.96440536.369600.596305.298403.88700K562TRIM56
ITM2CENSG00000135916.111139.52410906.757400.329503.532202.08910K562TROVE2
ITM2CENSG00000135916.11251.71700391.55510-0.637403.485902.58530K562U2AF2
ITM2CENSG00000135916.111146.88470820.499000.483007.260906.16330K562UPF1
ITM2CENSG00000135916.111633.868101055.640400.630103.213301.78370K562UTP18
ITM2CENSG00000135916.11585.64560730.09100-0.318002.790901.94080K562WDR43
ITM2CENSG00000135916.111502.267901041.968500.527706.099904.73610K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ITM2C is not available on ENCORE database.





5 RBPs can affect the splicing of ITM2C :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEITM2CENSG00000135916.11chr2+2317381312317382722317296642317298602317403342317405230.064000.006610.09409includedHepG2U2AF1
SEITM2CENSG00000135916.11chr2+2317381312317382722317296642317298602317403342317405230.087000.001330.09766includedHepG2PRPF8
SEITM2CENSG00000135916.11chr2+231738131231738272231729664231729860231740334231740523-0.153000.000000.00000excludedHepG2HNRNPK
SEITM2CENSG00000135916.11chr2+2317381312317382722317296642317298602317403342317405230.119000.000000.00003includedHepG2U2AF2
SEITM2CENSG00000135916.11chr2+231738131231738272231729664231729860231740334231740523-0.331000.000010.00674excludedK562SAFB

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ITM2C is not avaliable on ENCORE database.