HEXDC

General Information

Gene Name       : HEXDC
Gene ID             : ENSG00000169660.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HEXDC)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HEXDCENSG00000169660.163.144.263.70ENCSR000AEF
HepG2HEXDCENSG00000169660.1617.809.3113.55ENCSR985KAT
K562HEXDCENSG00000169660.167.875.836.85ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HEXDC is not avaliable on ENCORE database.



Proteins bound to RNA
  • HEXDC RNA is bound by 22 proteins.  







eCLIP assay for HEXDC is not avaliable on ENCORE database.





22 proteins are bound to HEXDC RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr178039164180391691+3'-UTR,CDS3.320496.93667HepG2PPIG
chr178039909780399131+3'-UTR,CDS,intron-Distal5.049217.95724HepG2PPIG
chr178039456380394638+3'-UTR,CDS,intron-Proximal4.7503215.11472HepG2PPIG
chr178039461280394686+3'-UTR,CDS,intron-Proximal5.0332711.38098K562PRPF8
chr178039889580398955+3'-UTR,CDS,intron-Proximal3.680487.28674HepG2PABPN1
chr178039371780393746+3'-UTR,CDS3.024895.21025HepG2PPIG
chr178039967980399737+3'-UTR,CDS,intron-Proximal5.116566.47877HepG2PABPN1
chr178039805080398121+3'-UTR,5'-UTR,CDS,intron-Distal3.559684.35635K562PRPF8
chr178040005380400061+3'-UTR,CDS3.474704.22917HepG2PPIG
chr178039974080399765+3'-UTR,CDS3.849944.96634HepG2PPIG
chr178040009480400199+3'-UTR,CDS3.7955010.57751HepG2PABPN1
chr178040024380400316+3'-UTR,CDS3.755148.16650HepG2LSM11
chr178039498380395050+3'-UTR,CDS,intron-Proximal3.7500621.18108HepG2SF3A3
chr178040035280400423+3'-UTR,CDS3.195893.21969HepG2ZC3H11A
chr178039157180391638+3'-UTR,CDS3.239308.07998HepG2PPIG
chr178039903780399139+3'-UTR,CDS,intron-Distal,intron-Proximal4.1021110.86975HepG2PABPN1
chr178039908180399137+3'-UTR,CDS,intron-Distal3.410944.00411HepG2LSM11
chr178039372880393794+3'-UTR,CDS,intron-Proximal3.996017.77750HepG2PRPF8
chr178040023180400303+3'-UTR,CDS4.612114.75108HepG2PABPN1
chr178039881980398886+3'-UTR,CDS,intron-Proximal4.8208412.47209HepG2SF3B4
chr178039890580398953+3'-UTR,CDS,intron-Proximal3.599385.57447HepG2GRWD1
chr178040037280400434+3'-UTR,CDS3.901065.81997HepG2LSM11
chr178039882580398890+3'-UTR,CDS,intron-Proximal4.126945.16342K562SF3B4
chr178040004680400097+3'-UTR,CDS,intron-Proximal3.459184.25147HepG2LSM11
chr178039505180395130+3'-UTR,CDS3.5261611.54327HepG2PPIG
chr178040010180400194+3'-UTR,CDS3.313458.57492HepG2LSM11
chr178039813280398190+3'-UTR,5'-UTR,intron-Distal4.227553.97409HepG2LSM11
chr178039356980393610+3'-UTR,CDS3.639898.19289HepG2PPIG
chr178039495880395076+3'-UTR,CDS,intron-Proximal4.0699510.56837K562SF3B4
chr178039364880393706+3'-UTR,CDS3.636517.91657HepG2PPIG
chr178037661080376647+5'-UTR,intron-Proximal3.815227.29769HepG2PRPF8
chr178038233380382365+5'-UTR,CDS,intron-Distal3.997666.36347HepG2PPIG
chr178037646680376528+5'-UTR3.752744.95606HepG2XPO5
chr178039802480398095+CDS,intron-Distal3.212663.29783HepG2RBM5
chr178039802380398100+CDS,intron-Distal3.430035.48466HepG2CDC40
chr178039516680395205+CDS4.150787.79455HepG2PPIG
chr178039522480395282+CDS,intron-Proximal3.363066.41278HepG2PRPF8
chr178039769380397785+CDS,intron-Distal3.525965.09513HepG2HNRNPK
chr178039802180398104+CDS,intron-Distal3.4582312.94827HepG2PPIG
chr178039944880399530+intron-Distal4.174943.30705HepG2GTF2F1
chr178038109480381157+intron-Distal4.922505.60971HepG2HLTF
chr178039928580399390+intron-Distal5.119579.07158HepG2RBFOX2
chr178039462780394719+intron-Distal,intron-Proximal3.946483.87927HepG2UCHL5
chr178039929080399382+intron-Distal5.247768.38577HepG2PRPF8
chr178039485580394901+intron-Distal4.132764.32536HepG2SF3B4
chr178039483380394898+intron-Distal3.156366.40081HepG2EFTUD2
chr178037901780379075+intron-Distal4.136053.82973HepG2HLTF
chr178039944980399520+intron-Distal3.851508.24222HepG2FAM120A
chr178039945180399522+intron-Distal4.665266.75874HepG2PRPF4
chr178038179580381945+intron-Distal4.094788.46970HepG2HNRNPK
chr178039464380394721+intron-Distal,intron-Proximal3.045873.31287HepG2GRWD1
chr178039735480397460+intron-Distal,intron-Proximal4.390683.87357K562EWSR1
chr178039942480399539+intron-Distal4.8554714.26711HepG2RBFOX2
chr178039552480395599+intron-Distal3.063255.73570K562PRPF8
chr178039464380394739+intron-Distal,intron-Proximal3.081894.88392HepG2FASTKD2
chr178039461780394676+intron-Proximal4.7314814.40768K562AQR
chr178039494680394983+intron-Proximal4.085747.43248HepG2SF3A3
chr178039495680395042+intron-Proximal4.8382817.19826HepG2SF3B4
chr178039463880394687+intron-Proximal3.422998.57574HepG2PPIG
chr178039462680394697+intron-Proximal4.3235526.28542HepG2EFTUD2
chr178039461480394617+intron-Proximal5.8441811.56697K562AQR
chr178039495980395015+intron-Proximal3.445636.18174HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HEXDC is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HEXDC is not available on ENCORE database.

  • 91 RBPs can affect the levels of HEXDC.  








The Knockdown/knockout RNA-Seq assay for HEXDC is not available on ENCORE database.





91 RBPs can affect the gene expression of HEXDC :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HEXDCENSG00000169660.11155.66010277.96720-0.836502.389101.38970HepG2AATF
HEXDCENSG00000169660.11842.76960596.253200.499102.819601.87000HepG2ABCF1
HEXDCENSG00000169660.11258.71170581.32350-1.1680021.1339019.80450HepG2ACO1
HEXDCENSG00000169660.11741.22840584.103200.343603.003602.20790HepG2AKAP8L
HEXDCENSG00000169660.11857.15440648.644500.402002.772502.08680HepG2AUH
HEXDCENSG00000169660.11413.94050197.550401.067104.759003.53020HepG2BCCIP
HEXDCENSG00000169660.11278.49130171.613100.698402.283101.46870HepG2BCLAF1
HEXDCENSG00000169660.11376.74620244.150800.625703.808103.11760HepG2BOP1
HEXDCENSG00000169660.11437.96730308.406000.505902.020601.37220HepG2CNOT7
HEXDCENSG00000169660.11469.56520340.843900.462103.796802.95180HepG2DAZAP1
HEXDCENSG00000169660.11705.29240556.184100.342602.794902.11450HepG2DKC1
HEXDCENSG00000169660.11318.64280186.801700.770306.004905.00080HepG2DNAJC21
HEXDCENSG00000169660.11306.39970185.151700.726606.164805.24810HepG2DNAJC2
HEXDCENSG00000169660.111106.53730438.069201.336705.495004.67570HepG2EIF2S1
HEXDCENSG00000169660.11587.20170322.114300.866204.269803.27200HepG2EIF4G2
HEXDCENSG00000169660.111139.10440744.816200.612803.926803.23180HepG2ETF1
HEXDCENSG00000169660.11356.00800568.10870-0.674304.114003.09640HepG2EWSR1
HEXDCENSG00000169660.11399.85260517.78380-0.372902.232501.51920HepG2FUBP3
HEXDCENSG00000169660.11693.08940453.152700.612902.354501.73780HepG2G3BP1
HEXDCENSG00000169660.11406.46130254.033400.678003.878403.13160HepG2GPKOW
HEXDCENSG00000169660.11427.48740285.557000.582002.782001.66690HepG2GRSF1
HEXDCENSG00000169660.11336.59470188.591300.835603.287002.59080HepG2HNRNPA1
HEXDCENSG00000169660.11436.63490303.850100.523004.143503.28450HepG2HNRNPF
HEXDCENSG00000169660.11402.41890310.484700.374102.374701.74440HepG2HNRNPL
HEXDCENSG00000169660.11443.44260242.432000.871106.641505.71230HepG2HNRNPLL
HEXDCENSG00000169660.11362.55540208.385900.798807.591706.62560HepG2HNRNPU
HEXDCENSG00000169660.11459.96200299.205100.620303.415802.61800HepG2IGF2BP1
HEXDCENSG00000169660.11358.00420212.859300.750007.326306.19450HepG2ILF2
HEXDCENSG00000169660.11723.28310531.438800.444605.173103.78610HepG2KIF1C
HEXDCENSG00000169660.11306.62390486.98190-0.667404.843503.79480HepG2MSI2
HEXDCENSG00000169660.11627.93690337.979700.893604.975903.95730HepG2NOL12
HEXDCENSG00000169660.11304.01950214.988500.499802.204401.53480HepG2NSUN2
HEXDCENSG00000169660.11394.56420185.863601.085908.321907.09060HepG2PPIL4
HEXDCENSG00000169660.11420.95830318.737600.401202.685801.92160HepG2PRPF4
HEXDCENSG00000169660.11892.26030322.629401.4675028.7484027.10180HepG2PUF60
HEXDCENSG00000169660.11498.12440342.483100.540405.323304.55440HepG2PUM1
HEXDCENSG00000169660.11517.97310342.234300.597804.944604.06220HepG2PUM2
HEXDCENSG00000169660.11102.90950271.79380-1.401102.296301.65100HepG2RAVER1
HEXDCENSG00000169660.11270.90300622.51070-1.2003010.747009.87230HepG2RBM22
HEXDCENSG00000169660.11281.99260471.99930-0.743106.254805.27710HepG2RBM25
HEXDCENSG00000169660.11726.68620310.009301.2289012.5815010.93140HepG2RPS3A
HEXDCENSG00000169660.11370.27410185.576900.996509.682008.59130HepG2SAFB2
HEXDCENSG00000169660.11480.17700291.918800.717904.621102.93360HepG2SART3
HEXDCENSG00000169660.11296.81320637.63430-1.1032010.136708.78270HepG2SF3A3
HEXDCENSG00000169660.11395.86960499.93590-0.336702.006501.48990HepG2SF3B4
HEXDCENSG00000169660.11549.49680309.346700.8288011.3562010.09440HepG2SLBP
HEXDCENSG00000169660.11423.62070703.07140-0.730905.565204.92260HepG2SRFBP1
HEXDCENSG00000169660.1165.28740521.84720-2.9988065.1264063.52300HepG2SRSF1
HEXDCENSG00000169660.11154.36430258.23440-0.742302.781601.77780HepG2SRSF3
HEXDCENSG00000169660.11195.78860424.56980-1.1167014.5241013.43900HepG2SRSF9
HEXDCENSG00000169660.11876.21160610.377400.521506.551605.82570HepG2SSB
HEXDCENSG00000169660.11460.27480269.784600.770604.184202.80090HepG2STIP1
HEXDCENSG00000169660.11332.24280193.343500.781003.259002.53190HepG2SUPV3L1
HEXDCENSG00000169660.11272.18830469.11870-0.785307.507706.65980HepG2TAF15
HEXDCENSG00000169660.11354.15160236.391700.583103.208002.43240HepG2TARDBP
HEXDCENSG00000169660.11391.23300202.486300.950109.160708.34360HepG2TIAL1
HEXDCENSG00000169660.11540.21320204.295901.4028026.1222024.60940HepG2TRIM56
HEXDCENSG00000169660.11467.75610315.191600.569404.059802.97770HepG2TUFM
HEXDCENSG00000169660.11200.75390514.84280-1.358709.852508.65540HepG2U2AF1
HEXDCENSG00000169660.11519.67210333.623000.639303.726802.74920HepG2UBE2L3
HEXDCENSG00000169660.11270.47030114.190201.243908.826507.46720HepG2UCHL5
HEXDCENSG00000169660.11325.56280176.952000.879502.519301.56420HepG2UPF2
HEXDCENSG00000169660.11736.94610581.236300.342302.860901.79800HepG2UTP18
HEXDCENSG00000169660.11288.26140545.95250-0.9214011.7575010.65800HepG2UTP3
HEXDCENSG00000169660.11602.85870277.694001.1182010.116208.06700HepG2XPO5
HEXDCENSG00000169660.11548.42190190.326501.5267015.6758013.97500HepG2XRN2
HEXDCENSG00000169660.11234.23960314.54530-0.425302.431801.79590HepG2ZC3H8
HEXDCENSG00000169660.11249.85920327.97520-0.392501.920801.43170K562AGGF1
HEXDCENSG00000169660.11205.63690368.24100-0.840605.225304.46340K562AQR
HEXDCENSG00000169660.11224.63440142.365900.657903.062801.66430K562BCCIP
HEXDCENSG00000169660.11285.80680137.617301.054304.265903.05670K562BCLAF1
HEXDCENSG00000169660.11183.67430105.961100.793502.853701.96710K562BOP1
HEXDCENSG00000169660.11216.59740139.441200.635303.080401.95730K562CCAR1
HEXDCENSG00000169660.11178.94380112.650300.667602.626101.86090K562CPSF6
HEXDCENSG00000169660.11192.16000104.403300.880004.227102.88420K562CSTF2
HEXDCENSG00000169660.11419.73680303.670700.466903.292701.96710K562DDX21
HEXDCENSG00000169660.11347.60980244.982500.504703.166202.40420K562EIF2S2
HEXDCENSG00000169660.11580.96260427.393100.442803.341802.31250K562EIF4G2
HEXDCENSG00000169660.11241.70550163.979300.559602.859401.57020K562EXOSC5
HEXDCENSG00000169660.11274.19020169.780700.691403.904802.88670K562FIP1L1
HEXDCENSG00000169660.11109.55010195.60670-0.836404.553603.80420K562FXR1
HEXDCENSG00000169660.11174.45890107.539900.697902.075101.38350K562GPKOW
HEXDCENSG00000169660.11272.68050405.72500-0.573303.382502.35950K562MBNL1
HEXDCENSG00000169660.11173.70470104.976600.726503.002902.08860K562METAP2
HEXDCENSG00000169660.11142.18600284.38430-1.000105.249403.89970K562NAA15
HEXDCENSG00000169660.11428.42780330.126700.375902.589401.86410K562NSUN2
HEXDCENSG00000169660.11316.59590192.743700.715904.552103.46230K562PPIG
HEXDCENSG00000169660.11212.18720136.615500.635102.543701.68220K562PSIP1
HEXDCENSG00000169660.11637.87160485.976200.392302.830501.86030K562PUM2
HEXDCENSG00000169660.11166.62130338.43930-1.022307.055606.23500K562PUS1
HEXDCENSG00000169660.11218.85630329.76770-0.591503.593102.93120K562RBM15
HEXDCENSG00000169660.11196.35400124.689700.655002.797401.80130K562RCC2
HEXDCENSG00000169660.1187.05640212.42790-1.287003.999902.47890K562SF1
HEXDCENSG00000169660.1135.4617097.71790-1.462405.388504.40870K562SRSF1
HEXDCENSG00000169660.11138.5111083.775100.725302.314001.36630K562SRSF4
HEXDCENSG00000169660.11144.1116092.293300.642802.370101.41000K562SRSF5
HEXDCENSG00000169660.11192.8448098.891500.963405.267604.27460K562TARDBP
HEXDCENSG00000169660.11178.1253095.393400.900804.619703.52080K562TIA1
HEXDCENSG00000169660.11150.0046093.622000.680002.389201.38960K562TRA2A
HEXDCENSG00000169660.11222.14170139.642100.669602.987801.99700K562TRIM56
HEXDCENSG00000169660.11186.89190112.053000.737902.442201.49160K562UCHL5
HEXDCENSG00000169660.11192.53420114.176500.753702.705801.51570K562XRN2
HEXDCENSG00000169660.11140.23270287.04980-1.033503.745901.78780K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HEXDC is not available on ENCORE database.





18 RBPs can affect the splicing of HEXDC :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHEXDCENSG00000169660.11chr17+8039834880398489803975068039758980398872803989510.610000.000000.00000includedHepG2HNRNPK
SEHEXDCENSG00000169660.11chr17+803822698038237980377624803777598038643380386521-0.209000.006380.07484excludedK562PUS1
SEHEXDCENSG00000169660.11chr17+803822698038236780377664803777598038643380386521-0.225000.001950.04336excludedHepG2SRSF1
SEHEXDCENSG00000169660.11chr17+8039799280398210803975068039758980398872803989510.316000.005160.09533includedK562AGGF1
SEHEXDCENSG00000169660.11chr17+803983488039848980397506803975898039887280398951-0.513000.000010.00056excludedHepG2HNRNPC
SEHEXDCENSG00000169660.11chr17+8039834880398489803975068039758980398872803989510.410000.000230.09684includedHepG2SLTM
SEHEXDCENSG00000169660.11chr17+803983488039848980397506803975898039887280398951-0.419000.000340.00770excludedK562HNRNPC
A3SSHEXDCENSG00000169660.11chr17+8039961980399765803996758039976580399028803991420.073000.000580.04602longerHepG2SF3A3
A5SSHEXDCENSG00000169660.11chr17+8039750680398210803975068039758980398872803989510.448000.000280.02269longerHepG2HNRNPK
A5SSHEXDCENSG00000169660.11chr17+8039750680398210803975068039758980398872803989510.606000.000280.03141longerK562UTP18
RIHEXDCENSG00000169660.11chr17+803988728039914280398872803989518039904080399142-0.529000.000010.00286excludedHepG2SFPQ
RIHEXDCENSG00000169660.11chr17+8039887280399142803988728039895180399040803991420.319000.002630.05220includedK562HNRNPC
RIHEXDCENSG00000169660.11chr17+8039887280399142803988728039895180399040803991420.328000.000170.00347includedHepG2PRPF8
RIHEXDCENSG00000169660.11chr17+803988728039914280398872803989518039904080399142-0.381000.000530.06622excludedK562UPF1
RIHEXDCENSG00000169660.11chr17+8039887280399142803988728039895180399040803991420.413000.000740.07102includedHepG2DROSHA
RIHEXDCENSG00000169660.11chr17+8039887280399142803988728039895180399040803991420.212000.000040.00119includedHepG2PCBP1
RIHEXDCENSG00000169660.11chr17+8039887280399142803988728039895180399040803991420.132000.009240.08079includedHepG2NCBP2
RIHEXDCENSG00000169660.11chr17+8039887280399142803988728039895180399040803991420.224000.001710.01455includedHepG2SF3B4
RIHEXDCENSG00000169660.11chr17+8039887280399142803988728039895180399040803991420.289000.000050.00096includedHepG2RBM22
RIHEXDCENSG00000169660.11chr17+8039887280399142803988728039895180399040803991420.173000.007010.08313includedHepG2SRSF9
RIHEXDCENSG00000169660.11chr17+8039887280399142803988728039895180399040803991420.281000.000000.00000includedHepG2HNRNPK
MXEHEXDCENSG00000169660.11chr17+8038226980382379803859058038600380377624803777598038643380386521-0.085000.000600.023742includedHepG2PCBP1
MXEHEXDCENSG00000169660.11chr17+8038226980382367803859058038600380377624803777598038643380386521-0.146000.001780.052952includedHepG2PCBP1
MXEHEXDCENSG00000169660.11chr17+8038229480382379803859058038600380377624803777598038643380386521-0.127000.004100.098082includedHepG2PCBP1
MXEHEXDCENSG00000169660.11chr17+80397992803982108039834880398489803975068039758980398872803989510.152000.002680.097201includedHepG2LARP4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HEXDC is not avaliable on ENCORE database.