ERLIN2

General Information

Gene Name       : ERLIN2
Gene ID             : ENSG00000147475.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ERLIN2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ERLIN2ENSG00000147475.1515.6014.8515.22ENCSR000AEF
HepG2ERLIN2ENSG00000147475.1534.2331.2332.73ENCSR985KAT
K562ERLIN2ENSG00000147475.1523.2120.7421.98ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ERLIN2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ERLIN2 RNA is bound by 15 proteins.  







eCLIP assay for ERLIN2 is not avaliable on ENCORE database.





15 proteins are bound to ERLIN2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr83761340037613450+3'-UTR4.828035.67997HepG2UPF1
chr83761283137612885+3'-UTR3.354608.00041K562UPF1
chr83761289837612958+3'-UTR4.899047.45692HepG2UPF1
chr83761361137613688+3'-UTR5.039698.19969HepG2UPF1
chr83761268437612727+3'-UTR6.5816219.19392HepG2LIN28B
chr83761291137612969+3'-UTR4.586243.49072HepG2FAM120A
chr83761260837612661+3'-UTR5.1936114.32888HepG2LIN28B
chr83761268537612734+3'-UTR5.241099.22045K562LIN28B
chr83761336237613412+3'-UTR4.061153.47103HepG2LIN28B
chr83761237837612420+3'-UTR4.302667.89119K562UPF1
chr83761268837612726+3'-UTR3.419184.61367K562UPF1
chr83761290637612955+3'-UTR5.8411811.61967K562UPF1
chr83761200937612065+3'-UTR3.295593.29348K562YBX3
chr83761260437612640+3'-UTR4.397794.44583HepG2UPF1
chr83761383337613921+3'-UTR3.260053.68829K562YBX3
chr83761310037613184+3'-UTR5.2711917.74444HepG2PCBP2
chr83761290437612959+3'-UTR4.724124.92659K562FAM120A
chr83761394737614010+3'-UTR3.813853.25175K562YBX3
chr83761291837612953+3'-UTR4.036113.08342HepG2AKAP1
chr83761195237612006+3'-UTR4.657386.75316K562YBX3
chr83761378737613866+3'-UTR4.007033.73296HepG2IGF2BP1
chr83761290737612950+3'-UTR3.963906.14899HepG2PCBP2
chr83761212737612170+3'-UTR5.101817.83423K562YBX3
chr83761258837612658+3'-UTR5.249848.55117K562LIN28B
chr83761312737613183+3'-UTR4.855827.21030HepG2UPF1
chr83761262237612640+3'-UTR4.553915.24231K562UPF1
chr83761325637613346+3'-UTR5.8583114.10191HepG2UPF1
chr83761284537612898+3'-UTR4.628766.23064HepG2UPF1
chr83759433937594476+5'-UTR,intron-Distal5.2695613.53182HepG2DDX3X
chr83759538437595607+5'-UTR,CDS,intron-Proximal3.945106.20417HepG2BUD13
chr83759926237599308+CDS,intron-Distal,intron-Proximal4.895794.65563K562AQR
chr83760188137601935+CDS,intron-Proximal4.023903.20743HepG2PPIG
chr83759785437598018+CDS,intron-Distal,intron-Proximal3.055265.68089HepG2BUD13
chr83761096737611048+CDS,intron-Proximal4.652333.77023K562ZNF622
chr83759795737598022+CDS,intron-Distal,intron-Proximal5.572517.36776HepG2PRPF8
chr83760208837602198+CDS,intron-Proximal4.113157.20197HepG2SND1
chr83761150437611629+CDS3.263474.24070HepG2GRWD1
chr83760208837602215+CDS,intron-Proximal4.388735.88075K562SND1
chr83761151837611608+CDS3.934954.12428HepG2SND1
chr83760709937607151+CDS,intron-Proximal4.525026.35450HepG2SND1
chr83760734837607413+CDS,intron-Proximal4.487555.05356HepG2PRPF8
chr83760791237608005+CDS,intron-Proximal4.509923.19000HepG2SND1
chr83761096837611049+CDS,intron-Proximal3.983138.40792HepG2PPIG
chr83761096637611047+CDS,intron-Proximal3.736755.74979HepG2GRWD1
chr83761097237611030+CDS3.941423.98500HepG2SND1
chr83759927537599373+CDS,intron-Distal,intron-Proximal4.018056.58230HepG2AQR
chr83759787837597965+CDS,intron-Distal,intron-Proximal3.049665.38711K562YBX3
chr83759796437598023+intron-Distal,intron-Proximal4.243366.39176K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ERLIN2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ERLIN2 is not available on ENCORE database.

  • 100 RBPs can affect the levels of ERLIN2.  








The Knockdown/knockout RNA-Seq assay for ERLIN2 is not available on ENCORE database.





100 RBPs can affect the gene expression of ERLIN2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ERLIN2ENSG00000147475.103542.804002259.386800.648906.824706.03090HepG2AKAP1
ERLIN2ENSG00000147475.10934.674201402.44890-0.585404.291603.12380HepG2BCCIP
ERLIN2ENSG00000147475.101029.288801425.78510-0.470104.478403.52700HepG2CALR
ERLIN2ENSG00000147475.101088.801401543.46850-0.5034010.423409.30270HepG2CKAP4
ERLIN2ENSG00000147475.101319.97990953.558700.469002.362101.65880HepG2CNOT7
ERLIN2ENSG00000147475.101814.402301424.356200.349103.253002.05290HepG2CPSF7
ERLIN2ENSG00000147475.102641.975701950.526900.437707.819606.84180HepG2CELF1
ERLIN2ENSG00000147475.101240.796601427.78910-0.202502.099701.36550HepG2DDX19B
ERLIN2ENSG00000147475.10737.006501448.52050-0.9748019.4302017.25820HepG2DDX24
ERLIN2ENSG00000147475.101567.305902164.38940-0.465704.031903.28800HepG2DDX3X
ERLIN2ENSG00000147475.101006.773401280.98900-0.347505.040304.20140HepG2DNAJC2
ERLIN2ENSG00000147475.101676.915901296.722300.370802.773501.85260HepG2EEF2
ERLIN2ENSG00000147475.10655.365501787.35210-1.4475028.8317027.05330HepG2EIF2S1
ERLIN2ENSG00000147475.101304.113301923.09610-0.560403.936703.12170HepG2EIF4B
ERLIN2ENSG00000147475.101600.731002069.11540-0.370305.838104.70140HepG2EIF4G1
ERLIN2ENSG00000147475.103270.587602402.999500.444609.403308.40330HepG2ETF1
ERLIN2ENSG00000147475.101414.310701070.248100.402103.690002.79030HepG2FUBP3
ERLIN2ENSG00000147475.101598.365501992.77420-0.318202.234001.60990HepG2FXR1
ERLIN2ENSG00000147475.101918.282901498.854700.355902.837101.80400HepG2GNB2L1
ERLIN2ENSG00000147475.101076.909901473.88460-0.452707.318105.82410HepG2HDGF
ERLIN2ENSG00000147475.102359.049901927.491400.291403.986602.89710HepG2HNRNPA2B1
ERLIN2ENSG00000147475.102129.551601392.013000.613307.142206.18530HepG2HNRNPLL
ERLIN2ENSG00000147475.101205.779801441.75790-0.257902.717702.11650HepG2HNRNPU
ERLIN2ENSG00000147475.10980.296201472.70960-0.5872014.2068012.68880HepG2ILF2
ERLIN2ENSG00000147475.103117.441002118.821900.557004.662603.57670HepG2LARP4
ERLIN2ENSG00000147475.101194.820001541.88500-0.367902.879801.64090HepG2LIN28B
ERLIN2ENSG00000147475.101999.695201413.474500.500406.246605.07690HepG2MSI2
ERLIN2ENSG00000147475.101497.628101186.905600.335402.910401.66390HepG2NAA15
ERLIN2ENSG00000147475.101573.817502051.91540-0.382702.793902.15800HepG2NCBP2
ERLIN2ENSG00000147475.101697.234301427.105600.250002.718501.87700HepG2PARN
ERLIN2ENSG00000147475.101248.080301893.25300-0.6012013.2907012.11700HepG2PCBP1
ERLIN2ENSG00000147475.10946.371101285.93460-0.442305.687404.66350HepG2PPIL4
ERLIN2ENSG00000147475.101530.038901264.538800.274903.118502.30220HepG2PRPF4
ERLIN2ENSG00000147475.101293.965001926.49500-0.5742011.6049010.63650HepG2PTBP1
ERLIN2ENSG00000147475.10907.052601985.25440-1.1301026.3027024.71740HepG2PUF60
ERLIN2ENSG00000147475.101231.092802107.42250-0.7755028.1704026.67680HepG2PUM1
ERLIN2ENSG00000147475.101144.861001572.44870-0.457808.288907.32150HepG2PUS1
ERLIN2ENSG00000147475.101094.940801699.49480-0.634303.616702.81360HepG2RAVER1
ERLIN2ENSG00000147475.101761.502602143.97130-0.283503.548502.95180HepG2NELFE
ERLIN2ENSG00000147475.101285.39080956.853900.425702.410801.66170HepG2RPS3A
ERLIN2ENSG00000147475.10681.923001052.46940-0.626104.782903.78130HepG2RRP9
ERLIN2ENSG00000147475.10852.288301283.95490-0.5912011.6175010.43800HepG2SAFB2
ERLIN2ENSG00000147475.101124.242901868.53680-0.733006.659205.58440HepG2SF3A3
ERLIN2ENSG00000147475.101107.673801377.80460-0.314802.302801.65620HepG2SF3B1
ERLIN2ENSG00000147475.101412.676802005.65950-0.505609.725608.71620HepG2SF3B4
ERLIN2ENSG00000147475.102200.577401903.523400.209102.747102.04830HepG2SLBP
ERLIN2ENSG00000147475.101288.292201497.31800-0.216902.497901.88210HepG2SMN1
ERLIN2ENSG00000147475.101787.473302268.53710-0.343805.798805.14740HepG2SRFBP1
ERLIN2ENSG00000147475.101637.031102093.50310-0.354805.586404.97370HepG2SRSF1
ERLIN2ENSG00000147475.102257.772001703.201000.406607.884307.03730HepG2SRSF9
ERLIN2ENSG00000147475.102692.607601969.683000.4509010.103409.24160HepG2SSB
ERLIN2ENSG00000147475.101619.721602229.22580-0.4608010.456909.37860HepG2SUCLG1
ERLIN2ENSG00000147475.101561.955301179.296200.405304.173003.03000HepG2SUPT6H
ERLIN2ENSG00000147475.102319.611201881.801900.301703.681503.05020HepG2TAF15
ERLIN2ENSG00000147475.10630.472901413.45820-1.1647038.0702036.27750HepG2TRIM56
ERLIN2ENSG00000147475.10890.125601493.99900-0.747109.430008.25770HepG2U2AF1
ERLIN2ENSG00000147475.10493.85050810.94630-0.715506.514005.34170HepG2UCHL5
ERLIN2ENSG00000147475.101073.930501657.10600-0.6258014.4088013.05170HepG2UPF1
ERLIN2ENSG00000147475.10859.885801599.87140-0.8957025.2676023.73420HepG2UTP3
ERLIN2ENSG00000147475.10921.873201351.27000-0.551704.454403.54160HepG2XRN2
ERLIN2ENSG00000147475.101047.638501247.94600-0.252402.784202.10990HepG2ZC3H8
ERLIN2ENSG00000147475.102490.933101822.500000.4507011.8021010.86720HepG2ZNF622
ERLIN2ENSG00000147475.101105.375801697.69980-0.619004.853803.08740HepG2ZRANB2
ERLIN2ENSG00000147475.10758.799801251.83370-0.7223014.2409013.05710K562AGGF1
ERLIN2ENSG00000147475.101071.493401375.47900-0.360303.142002.08050K562AKAP8
ERLIN2ENSG00000147475.10790.561301302.56580-0.720409.808508.48230K562AKAP8L
ERLIN2ENSG00000147475.101570.571702036.22220-0.374603.539202.11840K562APOBEC3C
ERLIN2ENSG00000147475.101184.245801875.46810-0.663309.039408.07670K562AQR
ERLIN2ENSG00000147475.101122.326901366.66000-0.284202.804001.88460K562ATP5C1
ERLIN2ENSG00000147475.101014.662801326.36180-0.386504.610202.84150K562BCCIP
ERLIN2ENSG00000147475.101061.510301281.74090-0.272002.852601.87760K562BCLAF1
ERLIN2ENSG00000147475.10853.518101217.31620-0.512205.892804.75200K562CPSF6
ERLIN2ENSG00000147475.10474.47710840.65170-0.8252013.3283010.04400K562DDX24
ERLIN2ENSG00000147475.10763.093901159.83100-0.604005.791004.44020K562EFTUD2
ERLIN2ENSG00000147475.10478.14930871.38550-0.8658016.3612013.49590K562EIF2S1
ERLIN2ENSG00000147475.10585.32850746.40880-0.350703.029101.80410K562EIF4B
ERLIN2ENSG00000147475.10661.78920917.11770-0.470703.359302.09780K562FKBP4
ERLIN2ENSG00000147475.10998.647301238.57440-0.310602.146401.38940K562FMR1
ERLIN2ENSG00000147475.101251.13370861.983100.537407.774306.82790K562FXR1
ERLIN2ENSG00000147475.10935.795201181.42120-0.336302.735101.31630K562G3BP1
ERLIN2ENSG00000147475.101623.577101965.73580-0.275902.245601.56140K562GRSF1
ERLIN2ENSG00000147475.10634.645401316.59710-1.052806.327504.21890K562HNRNPA2B1
ERLIN2ENSG00000147475.10851.167701056.59890-0.311902.214101.67130K562HNRNPC
ERLIN2ENSG00000147475.101090.008101482.55670-0.443705.790104.48520K562HNRNPU
ERLIN2ENSG00000147475.10941.272201235.76530-0.392702.424901.48280K562IGF2BP2
ERLIN2ENSG00000147475.10883.326801382.43150-0.646207.880906.31280K562KIF1C
ERLIN2ENSG00000147475.10775.120801071.50950-0.467203.687401.94120K562LIN28B
ERLIN2ENSG00000147475.10899.214901323.25930-0.557406.254804.38280K562MAK16
ERLIN2ENSG00000147475.10869.219701134.47710-0.384203.097102.16780K562METAP2
ERLIN2ENSG00000147475.10748.375801085.49170-0.536503.567102.53560K562NAA15
ERLIN2ENSG00000147475.101190.003001443.13170-0.278203.848202.98400K562NSUN2
ERLIN2ENSG00000147475.10551.683101152.17180-1.062406.336504.65430K562PABPN1
ERLIN2ENSG00000147475.10991.303601269.48970-0.356803.312301.82920K562PCBP1
ERLIN2ENSG00000147475.10911.108701155.50330-0.342802.581401.63720K562PCBP2
ERLIN2ENSG00000147475.101351.446101645.23870-0.283802.052301.34990K562PPIG
ERLIN2ENSG00000147475.102006.422002517.78830-0.327502.457401.69080K562PUF60
ERLIN2ENSG00000147475.10542.178501291.95870-1.2527022.5083020.98310K562PUS1
ERLIN2ENSG00000147475.10752.579001258.67760-0.7420012.9296011.64640K562RBM15
ERLIN2ENSG00000147475.10966.060801209.85190-0.324602.395301.61740K562RBM22
ERLIN2ENSG00000147475.10534.08080780.16050-0.546704.473902.72090K562RBM25
ERLIN2ENSG00000147475.10756.404201417.55140-0.906204.321702.27850K562RBM39
ERLIN2ENSG00000147475.10849.23250601.688800.497003.515802.37520K562RPS3
ERLIN2ENSG00000147475.101246.78810922.654400.434304.155702.81810K562SAFB
ERLIN2ENSG00000147475.10660.414901053.99120-0.674402.643901.48020K562SF1
ERLIN2ENSG00000147475.101160.101201423.97330-0.295703.051102.19640K562SF3A3
ERLIN2ENSG00000147475.10575.26870855.17430-0.572005.069003.89340K562SF3B4
ERLIN2ENSG00000147475.10658.908401209.97680-0.876804.160702.54610K562SNRNP200
ERLIN2ENSG00000147475.10504.73380819.28810-0.698807.171105.29230K562SRFBP1
ERLIN2ENSG00000147475.10823.250601236.95370-0.587407.256506.12150K562SRSF1
ERLIN2ENSG00000147475.101434.617402196.82610-0.6148010.198707.63240K562SUCLG1
ERLIN2ENSG00000147475.101381.145101038.613500.411104.445103.39800K562SYNCRIP
ERLIN2ENSG00000147475.10954.368601251.86550-0.391503.023702.28380K562TARDBP
ERLIN2ENSG00000147475.10949.456901207.56890-0.346902.963902.11320K562TIA1
ERLIN2ENSG00000147475.10889.520601185.01330-0.413803.404902.16670K562TRA2A
ERLIN2ENSG00000147475.10714.99810967.93310-0.437003.535202.44070K562TRIM56
ERLIN2ENSG00000147475.10718.934801156.71180-0.686106.100204.51800K562UCHL5
ERLIN2ENSG00000147475.10798.781001309.73870-0.713403.753002.17230K562UTP18
ERLIN2ENSG00000147475.10751.275801361.53430-0.8578023.4340021.34260K562WDR43
ERLIN2ENSG00000147475.101806.760902221.79500-0.298302.772801.48040K562WRN
ERLIN2ENSG00000147475.101484.568002112.91940-0.509206.272904.88600K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ERLIN2 is not available on ENCORE database.





2 RBPs can affect the splicing of ERLIN2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSERLIN2ENSG00000147475.10chr8+3760728837607370376073113760737037607076376071500.087000.003660.02196longerK562AQR
MXEERLIN2ENSG00000147475.10chr8+3759788237597964376018723760193437595425375955473760208837602214-0.212000.003920.085192includedK562DHX30

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ERLIN2 is not avaliable on ENCORE database.