COX5B

General Information

Gene Name       : COX5B
Gene ID             : ENSG00000135940.6
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: COX5B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COX5BENSG00000135940.610.9547.3129.13ENCSR000AEF
HepG2COX5BENSG00000135940.6137.7590.02113.88ENCSR985KAT
K562COX5BENSG00000135940.6203.22103.37153.30ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COX5B is not avaliable on ENCORE database.



Proteins bound to RNA
  • COX5B RNA is bound by 18 proteins.  







eCLIP assay for COX5B is not avaliable on ENCORE database.





18 proteins are bound to COX5B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr29826453198264580+3'-UTR,CDS5.417668.24403K562DDX6
chr29826460298264652+3'-UTR5.2382013.18422HepG2SUB1
chr29826446498264576+3'-UTR,CDS4.7560339.98489HepG2RPS3
chr29826453798264575+3'-UTR,CDS5.031807.12026HepG2G3BP1
chr29826459498264640+3'-UTR3.8406721.72524HepG2LARP4
chr29826454598264576+3'-UTR,CDS4.010849.94344K562RPS3
chr29826459598264636+3'-UTR4.7680550.24130K562PABPC4
chr29826460898264644+3'-UTR5.438017.66049K562LARP4
chr29826456798264577+3'-UTR,CDS4.8407133.14772HepG2LARP4
chr29826457198264585+3'-UTR3.9796419.41698K562YBX3
chr29826453698264581+3'-UTR,CDS4.559007.73743K562LARP4
chr29826456598264571+3'-UTR,CDS3.8262020.21463K562YBX3
chr29826254398262653+5'-UTR,CDS,intron-Proximal4.1805629.90201HepG2DDX3X
chr29826253498262615+5'-UTR,CDS3.8256258.84741K562DDX3X
chr29826253698262642+5'-UTR,CDS5.1962449.91073K562RPS3
chr29826253198262650+5'-UTR,CDS3.307024.37582K562EIF3G
chr29826253698262622+5'-UTR,CDS4.6595231.39864K562GEMIN5
chr29826253398262615+5'-UTR,CDS4.937504.61629K562NCBP2
chr29826253198262571+5'-UTR,CDS4.602778.11444HepG2SUB1
chr29826254398262546+5'-UTR4.052778.40205K562PABPC4
chr29826383098263857+CDS4.0734410.58465HepG2G3BP1
chr29826353798263598+CDS3.3948612.24692K562GEMIN5
chr29826389298263906+CDS4.113158.04249HepG2SUB1
chr29826385798263904+CDS4.1302311.57228HepG2G3BP1
chr29826448398264510+CDS5.6076060.49745HepG2LARP4
chr29826262298262650+CDS4.3730717.89432HepG2RPS3
chr29826357598263603+CDS6.8522855.02180HepG2LARP4
chr29826386398263880+CDS5.9527428.96434HepG2LARP4
chr29826380598263830+CDS,intron-Proximal3.5920610.76369HepG2G3BP1
chr29826261898262641+CDS3.8900444.10120K562DDX3X
chr29826445798264512+CDS,intron-Proximal5.0384421.04137HepG2SUB1
chr29826358798263638+CDS,intron-Proximal4.291216.81564HepG2PRPF8
chr29826453698264565+CDS3.5598632.56342K562YBX3
chr29826381498263862+CDS5.6207051.16557K562RPS3
chr29826264198262653+CDS,intron-Proximal3.7156633.95683K562DDX3X
chr29826263898262651+CDS4.8615918.68807HepG2LARP4
chr29826386298263895+CDS4.4303350.67664K562PABPC4
chr29826380698263816+CDS,intron-Proximal5.1478256.58964K562PABPC4
chr29826451098264534+CDS6.4458262.78722HepG2LARP4
chr29826357898263604+CDS,intron-Proximal5.1375730.10864K562APOBEC3C
chr29826380598263850+CDS,intron-Proximal4.2799413.47158HepG2DDX55
chr29826353398263578+CDS6.1727644.95769K562APOBEC3C
chr29826352798263573+CDS,intron-Proximal4.7183122.40806HepG2DDX55
chr29826450998264526+CDS3.3690314.44315K562YBX3
chr29826449598264518+CDS4.5305716.19302K562PABPC4
chr29826386098263887+CDS3.492388.10625K562APOBEC3C
chr29826380698263816+CDS,intron-Proximal3.943278.76135K562APOBEC3C
chr29826388798263906+CDS3.404664.63095K562DDX6
chr29826357398263603+CDS4.0670312.20722HepG2DDX55
chr29826353798263604+CDS,intron-Proximal3.0415014.40178K562DDX6
chr29826352998263532+CDS,intron-Proximal5.3045117.41359HepG2LARP4
chr29826353098263553+CDS3.5452115.90999K562DDX55
chr29826453598264567+CDS5.6199059.09434HepG2LARP4
chr29826447798264537+CDS5.8583713.92069HepG2G3BP1
chr29826355398263603+CDS3.6208135.31224K562DDX55
chr29826256198262571+CDS3.4956018.82848K562YBX3
chr29826264198262653+CDS,intron-Proximal3.888967.17827HepG2DDX55
chr29826385598263887+CDS3.917667.45170K562DDX6
chr29826388798263905+CDS3.502019.72004K562APOBEC3C
chr29826264998262698+CDS,intron-Proximal4.485993.25089HepG2AQR
chr29826352998263602+CDS,intron-Proximal4.0111338.21658HepG2RPS3
chr29826256098262614+CDS3.383649.97196HepG2DDX55
chr29826446198264488+CDS3.104966.50605K562APOBEC3C
chr29826257198262591+CDS3.4774620.42130K562YBX3
chr29826445898264505+CDS,intron-Proximal3.569508.05415K562DDX6
chr29826359598263603+CDS6.22401400.00000K562PABPC4
chr29826350298263653+CDS,intron-Proximal3.9250626.89531K562EFTUD2
chr29826359398263646+CDS,intron-Proximal3.300455.36110K562AQR
chr29826354298263604+CDS,intron-Proximal3.1013411.70797K562LARP4
chr29826388098263906+CDS5.0632930.96537HepG2LARP4
chr29826347998263591+CDS,intron-Proximal3.067316.97330HepG2AQR
chr29826352998263595+CDS,intron-Proximal6.09981400.00000K562PABPC4
chr29826382198263843+CDS4.2493031.06972K562PABPC4
chr29826380998263864+CDS4.7778327.34558HepG2RPS3
chr29826445998264477+CDS3.510673.97184HepG2G3BP1
chr29826445898264483+CDS,intron-Proximal4.8160636.02701HepG2LARP4
chr29826265198262688+CDS,intron-Proximal5.4334314.28850K562AQR
chr29826380698263814+CDS,intron-Proximal4.975958.13934K562RPS3
chr29826256998262607+CDS4.8276727.65712HepG2LARP4
chr29826381698263853+CDS3.172586.52908K562APOBEC3C
chr29826381498263861+CDS4.252238.78108K562LARP4
chr29826256198262622+CDS4.6801230.75711HepG2RPS3
chr29826381498263858+CDS5.8590845.97275HepG2LARP4
chr29826380698263814+CDS,intron-Proximal5.8712128.96434HepG2LARP4
chr29826352898263604+CDS,intron-Proximal3.1303012.14949HepG2G3BP1
chr29826355198263603+CDS5.6198961.43567K562RPS3
chr29826446598264564+CDS3.1089411.62895HepG2DDX55
chr29826385098263906+CDS3.761559.78821HepG2DDX55
chr29826353298263575+CDS7.1190762.80310HepG2LARP4
chr29826290098262941+intron-Distal,intron-Proximal3.495623.88924K562PRPF8
chr29826394098263996+intron-Proximal5.146217.96842K562PRPF8
chr29826265898262719+intron-Proximal4.796206.66402K562BUD13
chr29826348098263519+intron-Proximal3.965974.13013K562SF3B4
chr29826395098263992+intron-Proximal5.635777.84667K562EFTUD2
chr29826268898262695+intron-Proximal6.3067913.72936K562AQR
chr29826269598262744+intron-Proximal5.416115.69951K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COX5B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COX5B is not available on ENCORE database.

  • 100 RBPs can affect the levels of COX5B.  








The Knockdown/knockout RNA-Seq assay for COX5B is not available on ENCORE database.





100 RBPs can affect the gene expression of COX5B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COX5BENSG00000135940.22275.271001673.006900.443503.442802.39620HepG2ABCF1
COX5BENSG00000135940.22090.126001601.410500.384102.966502.15420HepG2ASCC1
COX5BENSG00000135940.22032.651101521.476300.417803.546902.67880HepG2CIRBP
COX5BENSG00000135940.21935.433301578.820900.293704.612603.79540HepG2CKAP4
COX5BENSG00000135940.21336.269001130.751500.240802.355601.75440HepG2CELF1
COX5BENSG00000135940.21825.980701460.589900.322005.137604.04770HepG2DDX19B
COX5BENSG00000135940.2509.90090896.52360-0.814102.164501.55640HepG2DDX21
COX5BENSG00000135940.23046.842701853.920900.716609.135508.05450HepG2DDX3X
COX5BENSG00000135940.2935.67320607.273100.623603.116301.68070HepG2DDX52
COX5BENSG00000135940.22764.891401592.965300.795409.524108.45070HepG2DDX6
COX5BENSG00000135940.2811.41230570.811100.507305.675104.69900HepG2DNAJC21
COX5BENSG00000135940.2891.77930565.721500.6565011.8707010.62100HepG2DNAJC2
COX5BENSG00000135940.21391.33810724.313400.941707.497806.06230HepG2EEF2
COX5BENSG00000135940.22346.886502639.16400-0.169301.859301.34580HepG2ETF1
COX5BENSG00000135940.21892.448601543.142800.294302.554301.75210HepG2EWSR1
COX5BENSG00000135940.2892.92090525.657400.764305.215203.57830HepG2FAM120A
COX5BENSG00000135940.2913.561901852.14780-1.0196021.1574019.09690HepG2FUBP3
COX5BENSG00000135940.21356.944101681.58280-0.309502.117001.34440HepG2G3BP2
COX5BENSG00000135940.2752.37440576.279000.384602.015801.45420HepG2HNRNPA1
COX5BENSG00000135940.21272.74470972.629200.387905.086004.15190HepG2HNRNPF
COX5BENSG00000135940.21684.920201107.399100.605403.706402.93350HepG2HNRNPL
COX5BENSG00000135940.21575.844901133.499200.475202.726902.10130HepG2HNRNPLL
COX5BENSG00000135940.21193.18750957.764600.317002.747802.02650HepG2IGF2BP1
COX5BENSG00000135940.22215.355801708.030900.375102.849102.18490HepG2MAGOH
COX5BENSG00000135940.22260.337801717.493900.396102.807202.17220HepG2MATR3
COX5BENSG00000135940.22596.724201757.871900.562805.581604.69570HepG2NCBP2
COX5BENSG00000135940.2944.56440655.326800.527302.985101.51950HepG2NIP7
COX5BENSG00000135940.21589.982401205.516400.399302.309001.61240HepG2NOL12
COX5BENSG00000135940.21224.71990567.933801.1086020.4177018.55310HepG2PPIL4
COX5BENSG00000135940.21981.910301150.801500.7842013.8778012.68260HepG2PUF60
COX5BENSG00000135940.21757.706501221.662400.5247013.0491011.96250HepG2PUM1
COX5BENSG00000135940.21664.378801220.747800.447105.767204.81040HepG2PUM2
COX5BENSG00000135940.22542.684502205.821400.204901.839001.39420HepG2RBM22
COX5BENSG00000135940.21542.21390874.080600.819107.665006.00260HepG2RBM27
COX5BENSG00000135940.2916.80290572.134200.680202.942102.31170HepG2RPS19
COX5BENSG00000135940.21340.37010806.044200.733602.560301.78880HepG2RPS2
COX5BENSG00000135940.21416.10680880.692500.685104.146303.16700HepG2RPS3A
COX5BENSG00000135940.21304.12380822.892900.664204.577003.18100HepG2RPS5
COX5BENSG00000135940.21189.34640567.064501.0685030.9185029.09890HepG2SAFB2
COX5BENSG00000135940.21636.328201103.512700.5683011.9641010.68050HepG2SLBP
COX5BENSG00000135940.2934.64550661.309200.499007.410306.43590HepG2SMN1
COX5BENSG00000135940.22021.817202491.33860-0.301304.933004.31810HepG2SRFBP1
COX5BENSG00000135940.21088.597401661.02030-0.6096013.0681012.20480HepG2SRSF1
COX5BENSG00000135940.21583.795901136.291700.479008.396707.38180HepG2SRSF5
COX5BENSG00000135940.21074.789401351.32550-0.330304.228403.57340HepG2SRSF9
COX5BENSG00000135940.22505.144202162.974800.211801.939401.49040HepG2SSB
COX5BENSG00000135940.21114.99160766.372400.540803.265602.06320HepG2STIP1
COX5BENSG00000135940.2956.365401492.98010-0.642605.345104.60810HepG2TAF15
COX5BENSG00000135940.21207.81590618.783600.964805.019504.38710HepG2TIAL1
COX5BENSG00000135940.21261.71600624.249501.0151017.1585015.91460HepG2TRIM56
COX5BENSG00000135940.21913.426101124.342700.767005.657604.35310HepG2TUFM
COX5BENSG00000135940.21956.747801630.427000.263103.370902.61280HepG2UPF1
COX5BENSG00000135940.21184.37540788.881800.586102.832701.72010HepG2XPO5
COX5BENSG00000135940.2724.12360953.32760-0.396704.797403.95360HepG2ZC3H8
COX5BENSG00000135940.22053.876101793.159600.195702.536602.00670HepG2ZNF622
COX5BENSG00000135940.25719.484403252.653400.8142016.4765015.21360K562AGGF1
COX5BENSG00000135940.25017.533203574.533000.489102.728501.75460K562AKAP8
COX5BENSG00000135940.26197.177403384.621500.872509.756208.43480K562AKAP8L
COX5BENSG00000135940.22616.094604804.24130-0.8769016.2346014.97200K562AQR
COX5BENSG00000135940.24345.482403551.449500.291002.164901.36440K562ATP5C1
COX5BENSG00000135940.21929.692601311.432500.5571011.381109.41190K562BCLAF1
COX5BENSG00000135940.2899.583601208.78690-0.426203.314202.35780K562BOP1
COX5BENSG00000135940.21379.51090944.270400.546804.144002.80020K562CCAR1
COX5BENSG00000135940.22126.363401656.832800.359903.238601.83630K562CIRBP
COX5BENSG00000135940.21019.384901285.19870-0.334302.491201.74520K562CPSF6
COX5BENSG00000135940.23271.792205177.94860-0.662309.622007.84830K562CELF1
COX5BENSG00000135940.22403.742402012.829300.256002.890101.54410K562DDX6
COX5BENSG00000135940.24535.025803641.542000.316502.433401.61970K562DKC1
COX5BENSG00000135940.21632.718301070.020300.609504.616102.92230K562EEF2
COX5BENSG00000135940.22604.894301873.711900.475204.532503.42750K562FIP1L1
COX5BENSG00000135940.2929.552801307.83060-0.492604.486603.39590K562FMR1
COX5BENSG00000135940.21849.704902157.05150-0.221802.142201.59770K562FXR1
COX5BENSG00000135940.2502.25650810.13630-0.689704.857003.85940K562G3BP2
COX5BENSG00000135940.22325.632303165.21560-0.444707.554305.73110K562GLRX3
COX5BENSG00000135940.21243.833902083.70940-0.744404.876702.79920K562HNRNPAB
COX5BENSG00000135940.22003.094803611.95300-0.850503.132102.18440K562HNRNPU
COX5BENSG00000135940.22367.592601546.421000.614405.106303.53650K562IGF2BP2
COX5BENSG00000135940.21980.255901572.702600.332302.880901.66010K562IGF2BP3
COX5BENSG00000135940.2897.697702033.35720-1.179608.422705.93550K562ILF2
COX5BENSG00000135940.24653.218303591.620200.373502.634401.83180K562KIF1C
COX5BENSG00000135940.2617.987101047.87160-0.761806.364404.88440K562KRR1
COX5BENSG00000135940.21976.144701624.691000.282402.412801.62480K562MAGOH
COX5BENSG00000135940.24685.541803438.315100.446404.492403.02630K562MAK16
COX5BENSG00000135940.25077.403304023.565000.335502.987002.03190K562MBNL1
COX5BENSG00000135940.23526.608104487.47640-0.347602.450601.38980K562MSI2
COX5BENSG00000135940.22156.793203327.83890-0.6257019.0519017.20750K562MTPAP
COX5BENSG00000135940.21663.519201018.966100.707004.941303.07620K562NONO
COX5BENSG00000135940.22472.617503697.37360-0.5805025.0126023.11650K562NSUN2
COX5BENSG00000135940.23136.317602127.306800.559902.983202.12660K562PPIG
COX5BENSG00000135940.21401.892301005.969800.478704.192703.27000K562PRPF8
COX5BENSG00000135940.23266.319204593.50530-0.491902.361701.60840K562PUF60
COX5BENSG00000135940.23230.724304887.00900-0.597108.994306.99210K562PUM1
COX5BENSG00000135940.25589.933703355.985200.7360012.4914011.38300K562PUS1
COX5BENSG00000135940.24844.497003270.424600.566806.886605.97890K562RBM15
COX5BENSG00000135940.21262.840301986.38140-0.653504.365002.34250K562RPS3A
COX5BENSG00000135940.21063.85930709.750100.583804.974903.58000K562RPS3
COX5BENSG00000135940.22414.909303648.59370-0.595407.672706.36680K562SF3A3
COX5BENSG00000135940.2681.307501167.15730-0.776607.185005.56880K562SF3B1
COX5BENSG00000135940.23251.837702083.933900.641804.763402.41640K562SMN1
COX5BENSG00000135940.22033.740203243.81140-0.673602.417701.30270K562SNRNP200
COX5BENSG00000135940.22741.005403738.08370-0.447608.170606.66060K562SRPK2
COX5BENSG00000135940.21891.805901547.545100.289702.515101.83610K562SRSF1
COX5BENSG00000135940.21211.61580685.136800.822406.427704.70500K562SRSF4
COX5BENSG00000135940.21899.279201461.688900.377703.321702.15240K562SRSF5
COX5BENSG00000135940.21621.289502248.11680-0.471602.648501.43160K562STAU1
COX5BENSG00000135940.21913.183701510.701600.340703.380602.46310K562TIA1
COX5BENSG00000135940.21937.953501482.755000.386202.313401.33420K562TRA2A
COX5BENSG00000135940.24155.844603472.586900.259004.135602.58300K562TROVE2
COX5BENSG00000135940.23247.813005179.99000-0.673508.171705.89780K562UBE2L3
COX5BENSG00000135940.22655.672603920.41590-0.5619016.4036014.82180K562UPF1
COX5BENSG00000135940.22348.730303354.55610-0.514207.782706.27000K562WDR3
COX5BENSG00000135940.22362.138803488.48610-0.5625012.8691011.20430K562WDR43
COX5BENSG00000135940.22091.681503818.62450-0.868403.348101.55430K562YTHDC2
COX5BENSG00000135940.24144.404605411.94360-0.385004.394203.26580K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COX5B is not available on ENCORE database.





1 RBPs can affect the splicing of COX5B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
MXECOX5BENSG00000135940.2chr2+9826352998263603982638069826390698262502982626529826445898264846-0.066000.008320.054552includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COX5B is not avaliable on ENCORE database.