C12orf57

General Information

Gene Name       : C12orf57
Gene ID             : ENSG00000111678.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: C12orf57)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878C12orf57ENSG00000111678.105.0543.9124.48ENCSR000AEF
HepG2C12orf57ENSG00000111678.10126.4218.9572.69ENCSR985KAT
K562C12orf57ENSG00000111678.1086.5027.8957.20ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for C12orf57 is not avaliable on ENCORE database.



Proteins bound to RNA
  • C12orf57 RNA is bound by 27 proteins.  







eCLIP assay for C12orf57 is not avaliable on ENCORE database.





27 proteins are bound to C12orf57 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1270550497055123+3'-UTR,CDS4.299295.79466HepG2RPS3
chr1270538867053938+3'-UTR,CDS,intron-Distal,intron-Proximal3.803933.07008K562NONO
chr1270550317055090+3'-UTR,CDS4.0513917.36046K562YBX3
chr1270550257055134+3'-UTR,CDS4.4774820.03017K562PABPC4
chr1270550907055136+3'-UTR5.7069712.38966HepG2LARP4
chr1270550207055090+3'-UTR,CDS4.3150410.83240HepG2LARP4
chr1270529987053048+5'-UTR,intron-Distal4.4388711.92327K562DDX52
chr1270532607053322+5'-UTR,CDS,intron-Distal,intron-Proximal3.182879.39889K562PABPC4
chr1270529947053048+5'-UTR,intron-Distal3.661233.45592K562NCBP2
chr1270529937052999+5'-UTR,intron-Distal8.90715400.00000K562LSM11
chr1270529787053045+5'-UTR,intron-Distal7.1573174.81623K562GEMIN5
chr1270529997053043+5'-UTR,intron-Distal4.0195342.75330HepG2SF3A3
chr1270529947053031+5'-UTR,intron-Distal3.7781554.67448K562DDX3X
chr1270529817053042+5'-UTR,intron-Distal4.875456.76194K562NOLC1
chr1270530027053014+5'-UTR,intron-Distal3.170814.30396K562UCHL5
chr1270530057053039+5'-UTR,intron-Distal4.4892310.20204K562PHF6
chr1270530077053046+5'-UTR,intron-Distal3.2993425.04290K562SMNDC1
chr1270529977053044+5'-UTR,intron-Distal5.314996.72851K562AATF
chr1270529947053045+5'-UTR,intron-Distal11.25772400.00000HepG2LSM11
chr1270534597053586+5'-UTR,intron-Distal,intron-Proximal4.585005.59615K562NONO
chr1270529967053044+5'-UTR,intron-Distal5.2952110.30553K562DDX51
chr1270529997053046+5'-UTR,intron-Distal11.11537400.00000K562LSM11
chr1270529987053044+5'-UTR,intron-Distal4.347726.71581HepG2SUB1
chr1270529957053051+5'-UTR,intron-Distal3.1922411.51535K562PUM2
chr1270530277053042+5'-UTR,intron-Distal5.5842216.90668HepG2EIF3D
chr1270532377053326+5'-UTR,CDS,intron-Distal,intron-Proximal4.015559.36557HepG2LARP4
chr1270530007053027+5'-UTR,intron-Distal5.7968619.21783HepG2EIF3D
chr1270530037053045+5'-UTR,intron-Distal3.1649311.94792K562FASTKD2
chr1270530067053039+5'-UTR,intron-Distal3.192968.48128K562SLBP
chr1270533237053432+5'-UTR,CDS,intron-Distal,intron-Proximal4.5788512.86643K562AQR
chr1270529947053030+5'-UTR,intron-Distal3.148118.47905HepG2HNRNPC
chr1270529817053007+5'-UTR,intron-Distal3.0702314.56059K562SMNDC1
chr1270529987053049+5'-UTR,intron-Distal6.082757.22444HepG2NCBP2
chr1270529807053043+5'-UTR,intron-Distal3.1175113.85546HepG2SMNDC1
chr1270536417053717+5'-UTR,CDS3.400594.48159HepG2LARP4
chr1270536467053720+5'-UTR,CDS3.608289.54233K562PABPC4
chr1270529987053046+5'-UTR,intron-Distal6.3751218.82594K562NSUN2
chr1270529797052994+5'-UTR,intron-Distal9.07663165.25175HepG2LSM11
chr1270530317053047+5'-UTR,intron-Distal3.8910356.85443K562DDX3X
chr1270537527053815+CDS,intron-Proximal4.268934.00197K562METAP2
chr1270549427054955+CDS6.5029327.02262K562LIN28B
chr1270549327054942+CDS,intron-Proximal5.3876911.26014K562LIN28B
chr1270537867053816+CDS,intron-Proximal3.292703.79722K562LIN28B
chr1270549557055005+CDS5.5902128.23375K562LIN28B
chr1270549337055009+CDS,intron-Proximal3.260573.70435HepG2LIN28B
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for C12orf57 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for C12orf57 is not available on ENCORE database.

  • 108 RBPs can affect the levels of C12orf57.  








The Knockdown/knockout RNA-Seq assay for C12orf57 is not available on ENCORE database.





108 RBPs can affect the gene expression of C12orf57 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
C12orf57ENSG00000111678.6245.93940125.254600.973303.088602.03970HepG2ADAR
C12orf57ENSG00000111678.6349.33040205.269200.767002.411701.57420HepG2BCLAF1
C12orf57ENSG00000111678.6574.88020331.207100.795405.507104.10810HepG2CCAR1
C12orf57ENSG00000111678.6281.13170360.83080-0.360102.170001.56990HepG2CKAP4
C12orf57ENSG00000111678.6284.06710138.863001.032506.973905.92190HepG2CPSF6
C12orf57ENSG00000111678.6217.44330128.452900.759303.274602.16600HepG2YBX3
C12orf57ENSG00000111678.6410.19850297.022000.465703.612302.78520HepG2DAZAP1
C12orf57ENSG00000111678.6315.14240126.115201.3212012.0916010.70430HepG2DNAJC21
C12orf57ENSG00000111678.6209.40070125.024600.744004.634103.82580HepG2DNAJC2
C12orf57ENSG00000111678.6187.36320293.02030-0.645204.134103.14980HepG2EIF4G1
C12orf57ENSG00000111678.6609.33070280.696501.118109.800708.31230HepG2EIF4G2
C12orf57ENSG00000111678.6527.56300677.18030-0.360203.089002.45980HepG2ETF1
C12orf57ENSG00000111678.6238.69120608.71970-1.3506019.9928017.97070HepG2FUBP3
C12orf57ENSG00000111678.6416.62890667.75130-0.680501.892201.33680HepG2G3BP1
C12orf57ENSG00000111678.6379.49840709.32990-0.902402.596401.73590HepG2G3BP2
C12orf57ENSG00000111678.6103.96330157.40280-0.598401.838101.30890HepG2GPKOW
C12orf57ENSG00000111678.6376.95220188.435801.000203.825802.19430HepG2HNRNPA0
C12orf57ENSG00000111678.6242.58470127.323700.929904.355803.56910HepG2HNRNPA1
C12orf57ENSG00000111678.6353.53950183.967300.942303.417001.85620HepG2HNRNPAB
C12orf57ENSG00000111678.6303.41430215.766400.491703.394402.60590HepG2HNRNPF
C12orf57ENSG00000111678.6694.40920270.567901.3597031.7405029.76520HepG2HNRNPL
C12orf57ENSG00000111678.6495.94760140.694801.817506.414205.52270HepG2HNRNPU
C12orf57ENSG00000111678.6431.36630286.186800.591902.986601.70480HepG2HSPD1
C12orf57ENSG00000111678.6312.82360212.472700.558003.744402.91230HepG2IGF2BP1
C12orf57ENSG00000111678.6203.76120143.713800.503602.479301.78150HepG2ILF2
C12orf57ENSG00000111678.6555.01290212.287701.386408.282606.10750HepG2KHDRBS1
C12orf57ENSG00000111678.6151.12480233.85610-0.629903.076601.79320HepG2NAA15
C12orf57ENSG00000111678.6457.99000741.35190-0.694801.873001.34540HepG2NCBP2
C12orf57ENSG00000111678.6325.25200191.973300.760604.550202.72300HepG2NIP7
C12orf57ENSG00000111678.6683.81010294.525801.2151013.1652011.55660HepG2NOL12
C12orf57ENSG00000111678.6141.3114074.836100.917003.059401.53170HepG2NOLC1
C12orf57ENSG00000111678.6393.68600203.364600.952903.879902.81580HepG2PABPC1
C12orf57ENSG00000111678.6229.43610659.84550-1.524004.890503.94150HepG2PABPC4
C12orf57ENSG00000111678.6523.63000724.88100-0.469205.021404.24080HepG2PCBP1
C12orf57ENSG00000111678.6282.05820125.487201.168409.725708.38890HepG2PPIL4
C12orf57ENSG00000111678.6131.72700195.52130-0.569802.304701.59170HepG2PRPF4
C12orf57ENSG00000111678.6334.03100737.58600-1.1428022.3743021.10400HepG2PTBP1
C12orf57ENSG00000111678.6770.35350281.147401.454105.166004.38310HepG2PUF60
C12orf57ENSG00000111678.6499.62450298.446500.743309.155308.20860HepG2PUM1
C12orf57ENSG00000111678.6429.02250298.230900.524503.507902.75660HepG2PUM2
C12orf57ENSG00000111678.6252.73000367.61560-0.540604.112203.38790HepG2PUS1
C12orf57ENSG00000111678.6342.10380798.83990-1.2235022.3061020.77930HepG2QKI
C12orf57ENSG00000111678.6726.80610565.997700.360702.946902.41700HepG2RBM22
C12orf57ENSG00000111678.6295.60370724.99250-1.2943021.2314019.47340HepG2RBM25
C12orf57ENSG00000111678.6439.39410256.058400.778904.782903.45980HepG2RBM27
C12orf57ENSG00000111678.6273.76490820.86860-1.5842037.6478036.15030HepG2NELFE
C12orf57ENSG00000111678.6391.87390764.51620-0.9642016.5227015.22260HepG2RECQL
C12orf57ENSG00000111678.6384.05180125.290401.6159024.4474022.79530HepG2SAFB2
C12orf57ENSG00000111678.61098.21760338.479701.697907.679306.51790HepG2SF3A3
C12orf57ENSG00000111678.6591.65680767.93570-0.376203.378302.73350HepG2SF3B4
C12orf57ENSG00000111678.6575.81940269.568601.0949010.073808.86640HepG2SLBP
C12orf57ENSG00000111678.6261.15540146.102200.837803.740303.01170HepG2SMN1
C12orf57ENSG00000111678.6294.82900639.27420-1.1166018.8595017.85780HepG2SRFBP1
C12orf57ENSG00000111678.6374.32190801.55310-1.0985021.0780020.02930HepG2SRSF1
C12orf57ENSG00000111678.6260.15730159.991100.701302.911801.87990HepG2SRSF3
C12orf57ENSG00000111678.6643.97720277.587401.2140022.3572020.81340HepG2SRSF5
C12orf57ENSG00000111678.6364.10860211.968200.780405.838004.88770HepG2SRSF7
C12orf57ENSG00000111678.6386.26370652.10140-0.7555010.918209.94970HepG2SRSF9
C12orf57ENSG00000111678.6383.61840555.04220-0.532905.232304.57050HepG2SSB
C12orf57ENSG00000111678.6392.63350231.278200.763502.413501.77660HepG2SUPV3L1
C12orf57ENSG00000111678.6224.94330720.45190-1.6793036.6786034.93870HepG2TAF15
C12orf57ENSG00000111678.6218.82970146.435800.579402.336201.66310HepG2TARDBP
C12orf57ENSG00000111678.6269.73440154.982300.799303.073602.02550HepG2TFIP11
C12orf57ENSG00000111678.6326.88690662.01340-1.018109.805108.25140HepG2TIA1
C12orf57ENSG00000111678.6397.20720137.935201.5258023.2499021.81330HepG2TRIM56
C12orf57ENSG00000111678.6567.15640274.662801.0460010.037708.17760HepG2TUFM
C12orf57ENSG00000111678.6222.49250136.583400.703902.381401.67690HepG2UCHL5
C12orf57ENSG00000111678.6521.50520289.811700.847506.836205.96600HepG2UTP3
C12orf57ENSG00000111678.6442.32010200.369701.142306.244604.60370HepG2XPO5
C12orf57ENSG00000111678.6460.49520227.669701.016103.398102.59970HepG2XRN2
C12orf57ENSG00000111678.6174.06480330.14020-0.923509.345308.49180HepG2ZNF622
C12orf57ENSG00000111678.6920.04550605.180500.604205.364204.61580K562AGGF1
C12orf57ENSG00000111678.6909.47480665.063300.451402.932401.91150K562AKAP8
C12orf57ENSG00000111678.61236.77970629.732900.973705.906304.92820K562AKAP8L
C12orf57ENSG00000111678.61266.16830719.983500.8143011.026109.96880K562AQR
C12orf57ENSG00000111678.6855.71570660.769900.372902.318701.49020K562ATP5C1
C12orf57ENSG00000111678.6699.34700365.605100.9356014.9476012.67740K562BCLAF1
C12orf57ENSG00000111678.6472.17870284.683300.729904.161502.81250K562CCAR1
C12orf57ENSG00000111678.6427.34640290.002900.559203.673202.18650K562CIRBP
C12orf57ENSG00000111678.6706.60720457.012700.628607.104405.30010K562CPEB4
C12orf57ENSG00000111678.6376.45490211.114500.834406.587305.37240K562CPSF6
C12orf57ENSG00000111678.6566.11670277.366001.0292012.9244010.44610K562CSTF2
C12orf57ENSG00000111678.6676.13590527.282300.358602.969601.71490K562DDX21
C12orf57ENSG00000111678.6764.91840584.373800.388303.068601.96770K562DDX3X
C12orf57ENSG00000111678.6327.78360472.83750-0.528604.563003.75350K562DDX47
C12orf57ENSG00000111678.6804.70260592.479700.441604.470702.67790K562DDX6
C12orf57ENSG00000111678.6493.38890237.929801.052103.595002.54480K562EFTUD2
C12orf57ENSG00000111678.61044.27870430.760501.2774028.7735026.89580K562EIF2S2
C12orf57ENSG00000111678.6768.68600549.817800.483305.087103.45360K562EIF4B
C12orf57ENSG00000111678.6547.75950245.604901.1571011.111709.29140K562FIP1L1
C12orf57ENSG00000111678.6281.13180182.045600.626803.149402.16950K562FTO
C12orf57ENSG00000111678.6325.10190634.92540-0.9657014.0758012.81510K562FXR1
C12orf57ENSG00000111678.663.94870161.20100-1.333906.576405.38300K562G3BP2
C12orf57ENSG00000111678.6324.28780201.568900.685904.187503.21640K562GPKOW
C12orf57ENSG00000111678.61090.49350573.914800.926004.026803.11800K562GRSF1
C12orf57ENSG00000111678.6725.08100332.921201.122908.079006.73570K562HSPD1
C12orf57ENSG00000111678.6771.89590270.721201.511502.981401.90440K562IGF2BP2
C12orf57ENSG00000111678.6411.46980275.303900.579703.298701.96500K562IGF2BP3
C12orf57ENSG00000111678.61009.94620668.251000.595704.875503.72260K562KIF1C
C12orf57ENSG00000111678.6434.64780284.378400.611904.558503.47220K562MAGOH
C12orf57ENSG00000111678.6894.16270639.723600.483004.502603.03500K562MAK16
C12orf57ENSG00000111678.6308.86440196.751000.650503.767002.73380K562METAP2
C12orf57ENSG00000111678.6588.45170235.005101.324106.195504.10580K562NONO
C12orf57ENSG00000111678.6687.27630494.308600.475405.327604.34110K562NSUN2
C12orf57ENSG00000111678.6459.47460278.044600.724606.476804.34410K562PCBP1
C12orf57ENSG00000111678.6516.33280345.671800.578804.702603.65750K562POLR2G
C12orf57ENSG00000111678.6724.24950278.878801.3767018.9815016.13860K562PPIG
C12orf57ENSG00000111678.61462.980801020.361400.519703.457102.38290K562PUM2
C12orf57ENSG00000111678.61265.27760624.414201.0188011.6547010.58840K562PUS1
C12orf57ENSG00000111678.6991.77370608.487100.704708.326807.32470K562RBM15
C12orf57ENSG00000111678.6401.29400264.864500.599303.575602.61080K562RBM22
C12orf57ENSG00000111678.6161.60860278.74530-0.786404.903103.39850K562NELFE
C12orf57ENSG00000111678.6774.31320487.732800.666706.596905.38530K562SF3A3
C12orf57ENSG00000111678.6526.52930270.883500.9587010.574409.20540K562SRSF1
C12orf57ENSG00000111678.6552.97410255.867601.111709.023707.03080K562SRSF5
C12orf57ENSG00000111678.6201.71410346.75700-0.781603.668602.72420K562SYNCRIP
C12orf57ENSG00000111678.6425.39170274.118100.633904.353503.45920K562TARDBP
C12orf57ENSG00000111678.6578.03520264.426701.1282014.0806012.11280K562TIA1
C12orf57ENSG00000111678.6576.27540259.560801.150608.970706.67060K562TRA2A
C12orf57ENSG00000111678.691.70750161.28120-0.814503.817402.87410K562U2AF2
C12orf57ENSG00000111678.6749.66370524.124700.516205.913704.90880K562UPF1
C12orf57ENSG00000111678.61110.83800633.200200.810804.914203.02330K562UTP18
C12orf57ENSG00000111678.6411.09690244.288800.750804.962603.35400K562UTP3
C12orf57ENSG00000111678.6294.10740466.35200-0.665107.110905.81230K562WDR43
C12orf57ENSG00000111678.6526.95790241.670301.124503.212301.87670K562XRN2
C12orf57ENSG00000111678.61175.62760810.925400.535703.562002.55990K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for C12orf57 is not available on ENCORE database.





11 RBPs can affect the splicing of C12orf57 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEC12orf57ENSG00000111678.6chr12+7053269705333670526647052825705363870538150.210000.000110.00332includedK562SRSF1
SEC12orf57ENSG00000111678.6chr12+7053269705333670526647052825705363870538150.053000.009300.07665includedK562AQR
SEC12orf57ENSG00000111678.6chr12+7053199705333670527047052825705363870538150.114000.000020.00333includedK562HNRNPUL1
SEC12orf57ENSG00000111678.6chr12+705363870537287053199705333670549337055165-0.108000.000040.03927excludedK562LARP7
SEC12orf57ENSG00000111678.6chr12+7053269705333670526647052825705363870538150.053000.000030.01098includedK562EIF4G2
SEC12orf57ENSG00000111678.6chr12+7053199705333670527047052825705363870538150.103000.000750.09868includedK562NPM1
A3SSC12orf57ENSG00000111678.6chr12+7053542705381570536387053815705319970533360.059000.000000.00000longerK562AQR
A5SSC12orf57ENSG00000111678.6chr12+705363870538157053638705372870549337055165-0.134000.000270.07831shorterHepG2SUPV3L1
A5SSC12orf57ENSG00000111678.6chr12+705363870538157053638705372870549337055165-0.228000.000000.00016shorterHepG2DDX55
A5SSC12orf57ENSG00000111678.6chr12+705363870538157053638705372870549337055165-0.137000.000000.00063shorterHepG2HNRNPL
A5SSC12orf57ENSG00000111678.6chr12+705363870538157053638705372870549337055165-0.176000.000000.00590shorterHepG2XRN2
A5SSC12orf57ENSG00000111678.6chr12+705363870538157053638705372870549337055165-0.105000.000040.02965shorterHepG2NOL12

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for C12orf57 is not avaliable on ENCORE database.