BCKDK

General Information

Gene Name       : BCKDK
Gene ID             : ENSG00000103507.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: BCKDK)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878BCKDKENSG00000103507.139.2813.9711.62ENCSR000AEF
HepG2BCKDKENSG00000103507.1337.4317.2027.31ENCSR985KAT
K562BCKDKENSG00000103507.1321.1015.0718.09ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for BCKDK is not avaliable on ENCORE database.



Proteins bound to RNA
  • BCKDK RNA is bound by 14 proteins.  







eCLIP assay for BCKDK is not avaliable on ENCORE database.





14 proteins are bound to BCKDK RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr163112358031123685+3'-UTR,CDS4.7590213.78695HepG2UPF1
chr163112359731123675+3'-UTR,CDS4.210553.27203K562IGF2BP2
chr163112253431122605+3'-UTR,CDS,intron-Proximal3.931319.30649HepG2PRPF8
chr163112330531123360+3'-UTR,CDS,intron-Proximal3.221255.39266HepG2GRWD1
chr163112036631120406+3'-UTR,5'-UTR,intron-Proximal4.5345914.67596HepG2DDX3X
chr163112047131120530+3'-UTR,5'-UTR3.427553.63043HepG2GRWD1
chr163112322031123305+3'-UTR,CDS4.465239.83058HepG2GRWD1
chr163112322331123352+3'-UTR,CDS,intron-Proximal3.929803.15171K562SRSF1
chr163112372831123864+3'-UTR,CDS3.136675.78757K562UPF1
chr163111973131119801+5'-UTR,intron-Distal,intron-Proximal3.902443.33524K562DDX3X
chr163111975231119802+5'-UTR,intron-Distal,intron-Proximal5.2193214.58841HepG2DDX3X
chr163112200831122045+CDS,intron-Distal,intron-Proximal5.003288.49217K562YBX3
chr163112181031121820+CDS4.879317.18289K562YBX3
chr163112110331121189+CDS,intron-Proximal4.1594715.11890HepG2PRPF8
chr163112198831122072+CDS,intron-Distal,intron-Proximal5.1064915.52132HepG2AQR
chr163112109631121106+CDS,intron-Proximal3.081886.23609K562YBX3
chr163112179331121810+CDS4.832766.51828K562YBX3
chr163112140831121445+CDS,intron-Proximal3.258594.47973K562YBX3
chr163112198031122026+CDS,intron-Distal,intron-Proximal3.777119.76099HepG2EFTUD2
chr163112181931121856+CDS,intron-Proximal3.355936.60938HepG2AQR
chr163112110231121165+CDS,intron-Proximal4.961414.65563K562AQR
chr163112152431121592+CDS,intron-Proximal3.917026.27819HepG2PPIG
chr163112159231121640+CDS4.978934.97342HepG2PPIG
chr163112199831122029+CDS,intron-Distal,intron-Proximal3.690863.69252K562EFTUD2
chr163112196731122031+CDS,intron-Distal,intron-Proximal4.308757.08947HepG2PRPF8
chr163112058531120661+CDS5.666477.49422HepG2DDX3X
chr163112084331120898+CDS3.196623.90824K562YBX3
chr163112205231122087+CDS,intron-Distal,intron-Proximal3.859954.41267HepG2PPIG
chr163112143531121444+CDS3.026863.21309HepG2GRWD1
chr163112175531121820+CDS3.580314.27261HepG2GRWD1
chr163112187431121947+intron-Distal,intron-Proximal5.058499.08640HepG2PRPF4
chr163112187031121921+intron-Distal,intron-Proximal4.892345.17615K562AQR
chr163112211231122150+intron-Distal,intron-Proximal3.662804.11859HepG2PRPF8
chr163112209531122185+intron-Distal,intron-Proximal4.8921721.15984HepG2EFTUD2
chr163112188531121934+intron-Distal,intron-Proximal3.489504.05505HepG2SF3B4
chr163112209431122150+intron-Distal,intron-Proximal4.647137.58326K562EFTUD2
chr163112188331121939+intron-Distal,intron-Proximal4.7584324.26113HepG2EFTUD2
chr163112256731122616+intron-Proximal5.497357.23906K562EFTUD2
chr163112112831121172+intron-Proximal3.872203.18234K562BUD13
chr163112236731122409+intron-Proximal6.096277.02785HepG2SF3A3
chr163112133331121391+intron-Proximal4.9716311.59041HepG2EFTUD2
chr163112167131121722+intron-Proximal4.844745.07796HepG2SF3B4
chr163112114731121194+intron-Proximal4.809515.25641HepG2BUD13
chr163112182031121861+intron-Proximal5.153908.04585HepG2PRPF8
chr163112133031121380+intron-Proximal5.567149.15758HepG2SF3B4
chr163112114031121187+intron-Proximal4.061727.83468HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for BCKDK is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for BCKDK is not available on ENCORE database.

  • 102 RBPs can affect the levels of BCKDK.  








The Knockdown/knockout RNA-Seq assay for BCKDK is not available on ENCORE database.





102 RBPs can affect the gene expression of BCKDK :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
BCKDKENSG00000103507.91164.821101508.59710-0.373103.486602.81750HepG2ACO1
BCKDKENSG00000103507.9553.41880760.73650-0.459002.700601.71420HepG2ADAR
BCKDKENSG00000103507.9941.264101391.56250-0.564002.986702.17110HepG2ASCC1
BCKDKENSG00000103507.91106.00110849.739000.380202.870202.26080HepG2BOP1
BCKDKENSG00000103507.9571.096501322.11880-1.211008.415007.12240HepG2CIRBP
BCKDKENSG00000103507.9993.404601508.06870-0.6022014.0824012.82300HepG2CKAP4
BCKDKENSG00000103507.9653.21830922.88470-0.498602.994702.29180HepG2DDX21
BCKDKENSG00000103507.9518.01150904.13230-0.803504.882703.65710HepG2DDX24
BCKDKENSG00000103507.9837.220401610.93530-0.944205.866004.98720HepG2DDX3X
BCKDKENSG00000103507.91072.52510771.578700.475002.685701.92150HepG2DDX55
BCKDKENSG00000103507.92036.967501384.431400.557004.789603.99640HepG2DDX6
BCKDKENSG00000103507.9957.950401443.26670-0.591308.247007.19840HepG2DKC1
BCKDKENSG00000103507.91102.24060766.020500.524906.415205.38120HepG2DNAJC21
BCKDKENSG00000103507.91093.88930759.266100.526709.348708.23410HepG2DNAJC2
BCKDKENSG00000103507.9593.46350800.17260-0.431203.061201.89860HepG2EFTUD2
BCKDKENSG00000103507.9571.71220779.23810-0.446803.008502.07050HepG2EIF3D
BCKDKENSG00000103507.9569.38450872.19510-0.615203.572402.36470HepG2EIF3G
BCKDKENSG00000103507.9748.781201469.83370-0.973006.282005.32430HepG2EIF4A3
BCKDKENSG00000103507.91008.607401315.46700-0.383204.734903.68570HepG2EIF4G1
BCKDKENSG00000103507.9726.641002038.42460-1.4881066.6673064.46270HepG2ETF1
BCKDKENSG00000103507.9943.278801473.99090-0.644005.704104.50070HepG2EWSR1
BCKDKENSG00000103507.9991.66060696.637400.509303.649302.28700HepG2FAM120A
BCKDKENSG00000103507.91352.538901958.86740-0.534302.262601.56270HepG2FIP1L1
BCKDKENSG00000103507.9437.57230642.17760-0.553503.985202.48250HepG2FKBP4
BCKDKENSG00000103507.9772.951901374.85200-0.830803.484802.60610HepG2FUBP3
BCKDKENSG00000103507.9966.137601461.46060-0.597102.982602.05750HepG2G3BP2
BCKDKENSG00000103507.91440.94300884.211000.704507.118406.12300HepG2GPKOW
BCKDKENSG00000103507.9487.06390773.35930-0.667006.074005.16850HepG2HNRNPA1
BCKDKENSG00000103507.9940.726501394.45730-0.567902.692202.00260HepG2HNRNPK
BCKDKENSG00000103507.91276.36240950.739700.424804.330903.44210HepG2IGF2BP1
BCKDKENSG00000103507.9972.457801398.56370-0.524202.456801.81620HepG2IGF2BP2
BCKDKENSG00000103507.9763.256101313.15370-0.782802.821101.83020HepG2IGF2BP3
BCKDKENSG00000103507.91027.56620872.878600.235302.493501.79370HepG2ILF2
BCKDKENSG00000103507.91750.518201378.922200.344105.879304.41480HepG2KIF1C
BCKDKENSG00000103507.9550.09410857.80300-0.641004.859902.66220HepG2LSM11
BCKDKENSG00000103507.91099.478501484.40090-0.433101.992401.43150HepG2MAGOH
BCKDKENSG00000103507.9992.13570550.381300.850006.516404.32340HepG2NOLC1
BCKDKENSG00000103507.9811.064701426.66860-0.8148019.4555018.08050HepG2PCBP1
BCKDKENSG00000103507.9663.366901271.46920-0.9386022.8276020.98650HepG2PRPF4
BCKDKENSG00000103507.9242.81890595.00570-1.2930015.6689013.96920HepG2PRPF8
BCKDKENSG00000103507.91197.461001451.72670-0.277802.958202.39610HepG2PTBP1
BCKDKENSG00000103507.91095.965101339.81050-0.289803.827703.15450HepG2PUM1
BCKDKENSG00000103507.91284.985001536.57460-0.258003.053802.41430HepG2PUS1
BCKDKENSG00000103507.9400.68670832.51150-1.055002.897902.17860HepG2RAVER1
BCKDKENSG00000103507.91014.56620429.837101.238904.223501.90820HepG2RBM17
BCKDKENSG00000103507.91137.641101703.72480-0.5826010.061609.21250HepG2RBM22
BCKDKENSG00000103507.91095.657001426.88020-0.381103.557902.80040HepG2RBM25
BCKDKENSG00000103507.91313.544101615.60080-0.298603.332702.75060HepG2NELFE
BCKDKENSG00000103507.91242.531401504.77000-0.276302.255601.69220HepG2RECQL
BCKDKENSG00000103507.9613.57750758.33080-0.305602.014201.48190HepG2RPS19
BCKDKENSG00000103507.9271.22650588.56370-1.1177011.367309.94500HepG2RRP9
BCKDKENSG00000103507.91385.01280760.999200.8638016.9724015.57180HepG2SAFB2
BCKDKENSG00000103507.9575.41430760.94830-0.403202.828801.87970HepG2SERBP1
BCKDKENSG00000103507.9976.76640415.430401.233304.346602.56040HepG2SF1
BCKDKENSG00000103507.9689.919801668.99290-1.2745016.8483015.11130HepG2SF3A3
BCKDKENSG00000103507.9586.92460835.17930-0.508903.505602.72030HepG2SF3B1
BCKDKENSG00000103507.9796.663301511.36650-0.9238023.8844022.43870HepG2SF3B4
BCKDKENSG00000103507.9870.75930402.965101.111503.303301.69380HepG2SFPQ
BCKDKENSG00000103507.91417.835601210.199800.228302.585301.90390HepG2SLBP
BCKDKENSG00000103507.9594.03570887.45050-0.579109.272408.20520HepG2SMN1
BCKDKENSG00000103507.91006.11560371.075701.438906.106603.98150HepG2SNRNP200
BCKDKENSG00000103507.9524.98470929.29810-0.823902.762201.98190HepG2SNRNP70
BCKDKENSG00000103507.9763.343801924.25730-1.3339058.7327057.19180HepG2SRFBP1
BCKDKENSG00000103507.9612.962401577.56740-1.3638049.6470048.19140HepG2SRSF1
BCKDKENSG00000103507.9483.60500898.77270-0.894106.685605.07550HepG2SRSF3
BCKDKENSG00000103507.9788.303801246.17550-0.6607012.1796010.99280HepG2SRSF5
BCKDKENSG00000103507.9943.670601283.45910-0.443706.648705.85950HepG2SRSF9
BCKDKENSG00000103507.9996.223701670.64610-0.7459019.4075018.31280HepG2SSB
BCKDKENSG00000103507.9378.87040768.03530-1.0195011.050609.84880HepG2SUPV3L1
BCKDKENSG00000103507.9782.976801418.05650-0.8569018.4241017.16200HepG2TAF15
BCKDKENSG00000103507.9502.240701225.10390-1.286505.051603.64360HepG2TBRG4
BCKDKENSG00000103507.9474.52760830.32810-0.8072011.2859010.39700HepG2TIAL1
BCKDKENSG00000103507.91112.53910837.763800.409105.319604.58880HepG2TRIM56
BCKDKENSG00000103507.9580.619601675.19510-1.5287011.111009.82980HepG2U2AF1
BCKDKENSG00000103507.91891.180101305.181800.534904.855003.72830HepG2UBE2L3
BCKDKENSG00000103507.9346.43590453.66150-0.389002.164201.49270HepG2UCHL5
BCKDKENSG00000103507.9764.043201429.01750-0.9033023.4616021.97220HepG2UTP3
BCKDKENSG00000103507.9979.792101254.73200-0.356804.795303.95190HepG2ZC3H8
BCKDKENSG00000103507.91138.41070647.018200.8150016.8781015.59890K562AGGF1
BCKDKENSG00000103507.91039.18420673.257400.626107.091506.00490K562AKAP8L
BCKDKENSG00000103507.9527.08240905.48040-0.780708.348407.41750K562AQR
BCKDKENSG00000103507.9871.96930706.419700.303702.578801.69920K562ATP5C1
BCKDKENSG00000103507.9640.70780456.442600.489103.503602.28900K562CCAR1
BCKDKENSG00000103507.9953.62870773.204000.302502.465101.36690K562CCDC124
BCKDKENSG00000103507.91216.97810865.114400.492203.236802.03400K562CPEB4
BCKDKENSG00000103507.91079.188501286.57910-0.253602.232601.35710K562CELF1
BCKDKENSG00000103507.9283.79560417.32040-0.556303.088501.99330K562EIF3D
BCKDKENSG00000103507.9887.150601046.19660-0.237902.148601.31540K562EIF4G2
BCKDKENSG00000103507.9719.41500563.882800.351302.517301.31420K562EXOSC5
BCKDKENSG00000103507.9327.54640448.77330-0.454302.415301.37420K562FKBP4
BCKDKENSG00000103507.9376.93260554.85380-0.557805.121504.33360K562FXR1
BCKDKENSG00000103507.958.79740191.38920-1.7027010.705309.13400K562G3BP2
BCKDKENSG00000103507.9353.05160516.45650-0.548803.999603.29800K562HNRNPC
BCKDKENSG00000103507.91130.33720855.847200.401203.962802.88780K562HNRNPU
BCKDKENSG00000103507.9611.69570338.275600.854504.317102.91620K562IGF2BP2
BCKDKENSG00000103507.9487.67680343.959100.503602.659001.49880K562IGF2BP3
BCKDKENSG00000103507.9509.83400354.471500.524303.328702.30480K562MATR3
BCKDKENSG00000103507.91172.96160800.394900.551306.976805.40800K562MBNL1
BCKDKENSG00000103507.9614.53640348.803500.817003.413602.28070K562PABPN1
BCKDKENSG00000103507.9794.52220608.357600.385102.689901.88370K562PPIG
BCKDKENSG00000103507.9237.68180379.42120-0.674803.608202.75070K562PRPF8
BCKDKENSG00000103507.9529.00950345.153700.616005.547704.63490K562PTBP1
BCKDKENSG00000103507.9703.243701141.45290-0.698807.596706.23990K562PUF60
BCKDKENSG00000103507.9968.091601214.30240-0.326903.103701.97230K562PUM1
BCKDKENSG00000103507.91004.79330667.646500.589605.907205.15070K562PUS1
BCKDKENSG00000103507.9922.03710650.554200.503105.726204.89940K562RBM15
BCKDKENSG00000103507.9484.50910330.808400.550402.201601.45580K562RBM22
BCKDKENSG00000103507.9260.29220411.64290-0.661303.057802.03470K562SF3B1
BCKDKENSG00000103507.9768.06550388.694300.982504.612502.75450K562SFPQ
BCKDKENSG00000103507.9549.56550400.654100.455802.862201.81430K562SRFBP1
BCKDKENSG00000103507.9423.27060274.724900.623504.060902.75000K562SRSF4
BCKDKENSG00000103507.9480.64280319.668300.588304.299302.94490K562SRSF5
BCKDKENSG00000103507.9437.97630551.83390-0.333402.090001.37570K562SYNCRIP
BCKDKENSG00000103507.9444.16530324.295500.453702.573301.52600K562TRA2A
BCKDKENSG00000103507.9610.36930473.343600.366702.236901.39920K562TRIM56
BCKDKENSG00000103507.91261.358401042.026800.275502.812101.53180K562TROVE2
BCKDKENSG00000103507.9106.20550191.59830-0.851204.620003.58820K562U2AF2
BCKDKENSG00000103507.9784.444301020.07960-0.378903.041502.13230K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for BCKDK is not available on ENCORE database.





19 RBPs can affect the splicing of BCKDK :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEBCKDKENSG00000103507.9chr16+311226203112271031121721311225403112318931123348-0.113000.000000.00002excludedHepG2U2AF1
SEBCKDKENSG00000103507.9chr16+311226203112271031121721311225403112318931123348-0.068000.000530.00817excludedHepG2U2AF2
SEBCKDKENSG00000103507.9chr16+311220083112208231121721311218203112241131122540-0.084000.001800.02003excludedK562AQR
SEBCKDKENSG00000103507.9chr16+311220083112208231121721311218203112241131122540-0.077000.000110.03057excludedHepG2PRPF4
A3SSBCKDKENSG00000103507.9chr16+3112081331120900311208313112090031120440311207390.072000.000020.00333longerHepG2RBM22
RIBCKDKENSG00000103507.9chr16+3112099331121445311209933112110431121397311214450.218000.000000.00000includedK562PUS1
RIBCKDKENSG00000103507.9chr16+3112318931123888311231893112334831123441311238880.138000.004640.04778includedHepG2SF3A3
RIBCKDKENSG00000103507.9chr16+3112318931123888311231893112334831123441311238880.210000.001520.09899includedK562HNRNPU
RIBCKDKENSG00000103507.9chr16+311209933112144531120993311211043112142431121445-0.101000.004770.05218excludedHepG2PRPF8
RIBCKDKENSG00000103507.9chr16+311209933112144531120993311211043112139731121445-0.072000.000190.01695excludedK562NCBP2
RIBCKDKENSG00000103507.9chr16+3112099331121445311209933112110431121397311214450.102000.000000.00010includedK562AGGF1
RIBCKDKENSG00000103507.9chr16+3112318931123888311231893112334831123441311238880.290000.000000.00000includedHepG2PCBP1
RIBCKDKENSG00000103507.9chr16+3112318931123888311231893112334831123441311238880.210000.000030.00135includedHepG2SRSF1
RIBCKDKENSG00000103507.9chr16+3112099331121445311209933112110431121397311214450.084000.000050.00087includedK562AKAP8L
RIBCKDKENSG00000103507.9chr16+3112318931123888311231893112334831123441311238880.253000.000000.00010includedHepG2TAF15
RIBCKDKENSG00000103507.9chr16+3112099331121445311209933112110431121397311214450.089000.000030.00058includedK562RBM15
RIBCKDKENSG00000103507.9chr16+3112099331121445311209933112110431121397311214450.081000.000000.00000includedHepG2RBM22
RIBCKDKENSG00000103507.9chr16+3112318931123888311231893112334831123441311238880.158000.000160.00478includedHepG2SRSF9
RIBCKDKENSG00000103507.9chr16+3112099331121445311209933112110431121397311214450.096000.000030.00080includedK562UTP18
RIBCKDKENSG00000103507.9chr16+3112318931123888311231893112334831123441311238880.173000.018400.09174includedK562AQR
RIBCKDKENSG00000103507.9chr16+3112099331121445311209933112110431121397311214450.088000.000600.00423includedK562AQR
RIBCKDKENSG00000103507.9chr16+311217213112254031121721311218203112241131122540-0.197000.003990.06323excludedK562PTBP1
RIBCKDKENSG00000103507.9chr16+311209933112144531120993311211043112139731121445-0.065000.001260.02577excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for BCKDK is not avaliable on ENCORE database.