XAB2

General Information

Gene Name       : XAB2
Gene ID             : ENSG00000076924.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: XAB2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878XAB2ENSG00000076924.111.487.724.60ENCSR000AEF
HepG2XAB2ENSG00000076924.1134.376.8220.59ENCSR985KAT
K562XAB2ENSG00000076924.1124.4613.4618.96ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for XAB2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • XAB2 RNA is bound by 22 proteins.  







eCLIP assay for XAB2 is not avaliable on ENCORE database.





22 proteins are bound to XAB2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1976860287686114-CDS,intron-Distal3.077064.38928K562FXR2
chr1976886897688729-CDS,intron-Distal3.110914.24993HepG2PPIG
chr1976848477684915-CDS,intron-Distal3.918463.59112HepG2PPIG
chr1976859057685976-CDS,intron-Distal,intron-Proximal3.594805.01857K562SMNDC1
chr1976893097689375-CDS,intron-Distal,intron-Proximal3.636865.83621K562AQR
chr1976859177685978-CDS,intron-Distal,intron-Proximal7.6143437.06975K562SF3B4
chr1976873727687438-CDS,intron-Distal,intron-Proximal4.009745.64484HepG2PRPF8
chr1976872087687291-CDS,intron-Distal,intron-Proximal3.536564.72836K562ZNF800
chr1976877617687805-CDS,intron-Distal,intron-Proximal3.939927.16774K562AQR
chr1976923087692378-CDS,intron-Distal,intron-Proximal4.390013.93614HepG2AQR
chr1976930347693080-CDS,intron-Distal,intron-Proximal3.590128.00668K562YBX3
chr1976877697687778-CDS,intron-Distal3.345843.36945K562ZNF622
chr1976887527688767-CDS,intron-Distal4.120223.20743HepG2PPIG
chr1976909717691043-CDS,intron-Distal,intron-Proximal4.522746.23016HepG2PRPF8
chr1976909017690931-CDS,intron-Distal,intron-Proximal3.601815.55970K562YBX3
chr1976860417686108-CDS,intron-Distal4.723939.05846K562FMR1
chr1976893007689403-CDS,intron-Distal,intron-Proximal4.408239.62011K562SF3B4
chr1976846937684743-CDS,intron-Distal,intron-Proximal3.165895.13857HepG2PABPN1
chr1976846387684693-CDS,intron-Distal3.142493.50122K562DDX55
chr1976857607685914-CDS,intron-Distal,intron-Proximal4.006535.92795K562METAP2
chr1976931757693221-CDS,intron-Distal,intron-Proximal4.734824.86944K562AQR
chr1976909067690982-CDS,intron-Distal,intron-Proximal3.572754.41255K562SMNDC1
chr1976910217691031-CDS,intron-Distal,intron-Proximal3.427104.74241K562YBX3
chr1976942767694385-CDS,intron-Distal3.379598.70001HepG2PRPF8
chr1976860977686184-CDS,intron-Distal,intron-Proximal3.962553.84295K562GRWD1
chr1976872207687264-CDS,intron-Distal4.482364.78571K562UCHL5
chr1976920917692149-CDS,intron-Distal,intron-Proximal4.127475.34978HepG2PRPF8
chr1976881167688172-CDS,intron-Distal3.605955.95375K562ZNF622
chr1976880557688100-CDS,intron-Distal,intron-Proximal4.091317.97611K562DDX24
chr1976871777687246-CDS,intron-Distal,intron-Proximal4.4343510.32997HepG2PRPF8
chr1976924847692594-intron-Distal,intron-Proximal5.8168113.60698HepG2RBFOX2
chr1976906927690766-intron-Distal,intron-Proximal3.172064.83230K562AQR
chr1976859247685977-intron-Distal,intron-Proximal4.186136.89981K562EFTUD2
chr1976853447685405-intron-Distal,intron-Proximal4.8151210.44900K562SF3B4
chr1976925007692546-intron-Distal,intron-Proximal4.625575.24155K562BUD13
chr1976924587692547-intron-Distal,intron-Proximal4.283894.07596K562GTF2F1
chr1976923907692459-intron-Distal,intron-Proximal4.362864.80493K562RBFOX2
chr1976924987692552-intron-Distal,intron-Proximal5.7085910.04245K562AQR
chr1976924627692554-intron-Distal,intron-Proximal4.262414.61288HepG2PRPF4
chr1976859267685980-intron-Distal,intron-Proximal3.530417.33329HepG2SF3B4
chr1976924727692547-intron-Distal,intron-Proximal5.034178.54263K562RBFOX2
chr1976853497685405-intron-Distal,intron-Proximal4.366174.22101K562PRPF8
chr1976924897692538-intron-Distal,intron-Proximal5.308006.36664K562DDX24
chr1976851387685161-intron-Distal,intron-Proximal4.319795.97994K562AQR
chr1976924037692484-intron-Distal,intron-Proximal3.943017.07105HepG2RBFOX2
chr1976851177685138-intron-Distal,intron-Proximal5.319796.75320K562AQR
chr1976942477694363-intron-Distal6.0456811.02807K562AQR
chr1976923327692424-intron-Distal,intron-Proximal3.643396.71722K562SF3B4
chr1976925067692540-intron-Distal,intron-Proximal3.292393.07653K562ZNF622
chr1976924957692593-intron-Distal,intron-Proximal4.490833.93614HepG2AQR
chr1976883257688476-intron-Distal4.766347.23552K562HNRNPK
chr1976909317690984-intron-Distal,intron-Proximal4.5237110.68651K562SF3B4
chr1976898967690030-intron-Distal5.369656.40247K562SF3B4
chr1976853657685404-intron-Distal,intron-Proximal3.275873.75245K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for XAB2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for XAB2 is not available on ENCORE database.

  • 94 RBPs can affect the levels of XAB2.  








The Knockdown/knockout RNA-Seq assay for XAB2 is not available on ENCORE database.





94 RBPs can affect the gene expression of XAB2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
XAB2ENSG00000076924.7913.09910769.228000.247302.148901.59860HepG2ACO1
XAB2ENSG00000076924.71198.42670865.595600.469301.854301.40930HepG2AKAP1
XAB2ENSG00000076924.7360.10600525.25720-0.544604.001703.09740HepG2CALR
XAB2ENSG00000076924.7207.22050391.15560-0.916602.675001.35220HepG2CSTF2T
XAB2ENSG00000076924.7659.63500490.497800.427303.837803.10260HepG2CELF1
XAB2ENSG00000076924.7665.48600527.396400.335403.089302.31270HepG2DAZAP1
XAB2ENSG00000076924.7267.52730412.17710-0.623604.341303.18750HepG2DDX24
XAB2ENSG00000076924.7643.80560370.800400.795902.161601.46980HepG2DDX55
XAB2ENSG00000076924.7990.34570712.526500.474902.051301.51260HepG2DDX6
XAB2ENSG00000076924.7414.43130316.463000.389002.435601.77090HepG2DNAJC21
XAB2ENSG00000076924.7522.22540313.726600.735109.180608.07410HepG2DNAJC2
XAB2ENSG00000076924.7237.90360387.82500-0.705003.980102.63810HepG2AGO1
XAB2ENSG00000076924.7397.35230520.31680-0.389002.643001.82140HepG2EIF4G1
XAB2ENSG00000076924.71081.39620763.698300.501702.615901.94370HepG2FXR1
XAB2ENSG00000076924.7800.10630594.914000.427404.839503.92450HepG2HNRNPF
XAB2ENSG00000076924.7765.85120480.414900.6727010.680509.43450HepG2HNRNPL
XAB2ENSG00000076924.7646.04020353.047700.8717010.842309.70880HepG2HNRNPU
XAB2ENSG00000076924.7457.58810360.623300.343501.927301.30110HepG2ILF2
XAB2ENSG00000076924.7756.64300522.965600.532805.555604.48030HepG2NOL12
XAB2ENSG00000076924.7557.67220358.123800.638903.195101.63860HepG2NOLC1
XAB2ENSG00000076924.7612.90650340.809300.846602.364301.36120HepG2NONO
XAB2ENSG00000076924.7832.37020427.472000.961303.783302.73130HepG2PABPC1
XAB2ENSG00000076924.7571.56560314.887000.8600011.298909.86550HepG2PPIL4
XAB2ENSG00000076924.7746.73950499.219000.580805.416704.61790HepG2PUF60
XAB2ENSG00000076924.7821.34550529.946000.6320010.347509.35400HepG2PUM1
XAB2ENSG00000076924.7778.67730529.557000.556104.536703.68870HepG2PUM2
XAB2ENSG00000076924.71298.684101044.054400.314802.702401.85260HepG2RBM15
XAB2ENSG00000076924.7581.188201013.12700-0.8017012.8401011.88750HepG2RBM22
XAB2ENSG00000076924.7524.33960387.687100.435502.673702.06840HepG2RPS19
XAB2ENSG00000076924.7626.75050314.393300.9952017.0572015.65380HepG2SAFB2
XAB2ENSG00000076924.71288.29590891.562700.531003.589602.81840HepG2SF3A3
XAB2ENSG00000076924.7806.45150478.679200.7524013.1493011.81360HepG2SLBP
XAB2ENSG00000076924.7525.05850366.616500.518105.213104.37780HepG2SMN1
XAB2ENSG00000076924.7703.67660367.137400.938504.266003.05910HepG2SMNDC1
XAB2ENSG00000076924.7457.68850727.25110-0.668103.800002.87860HepG2SNRNP70
XAB2ENSG00000076924.71361.065401144.269400.250202.515002.02940HepG2SRFBP1
XAB2ENSG00000076924.7627.33860838.82850-0.419103.865003.32910HepG2SRSF1
XAB2ENSG00000076924.7812.83340492.909600.7215011.1889010.04350HepG2SRSF5
XAB2ENSG00000076924.7720.92270584.467100.302602.643901.96300HepG2SRSF7
XAB2ENSG00000076924.7835.59040560.571000.575808.460307.47180HepG2SUCLG1
XAB2ENSG00000076924.7326.47410754.07780-1.2077011.9946010.95430HepG2TAF15
XAB2ENSG00000076924.7506.97720342.979400.563703.487302.93950HepG2TIAL1
XAB2ENSG00000076924.7642.13610346.123200.8915014.1639013.02920HepG2TRIM56
XAB2ENSG00000076924.7673.05870487.720600.464603.068202.14250HepG2TUFM
XAB2ENSG00000076924.7821.20540454.034200.854802.289901.40340HepG2U2AF2
XAB2ENSG00000076924.7865.44300516.247800.745302.343501.57820HepG2UBE2L3
XAB2ENSG00000076924.7358.99020217.928500.720002.224501.54380HepG2UCHL5
XAB2ENSG00000076924.7586.48060790.67990-0.431004.507803.65230HepG2UPF1
XAB2ENSG00000076924.7690.75820363.270100.927003.475502.66840HepG2XRN2
XAB2ENSG00000076924.73780.502002091.008400.8543017.3061016.00760K562AGGF1
XAB2ENSG00000076924.71667.067001310.267800.347403.664701.90550K562AKAP1
XAB2ENSG00000076924.73270.644702297.929700.509105.945004.36970K562AKAP8
XAB2ENSG00000076924.73537.094302175.845000.700905.586304.64110K562AKAP8L
XAB2ENSG00000076924.72386.354601865.780700.354903.343102.71010K562AQR
XAB2ENSG00000076924.73099.712802283.091000.441003.263902.26580K562ATP5C1
XAB2ENSG00000076924.71228.25750787.864900.6405011.363609.39780K562BCLAF1
XAB2ENSG00000076924.71000.58090773.297700.371603.033802.21350K562CPSF6
XAB2ENSG00000076924.71078.00210597.713000.8507014.1910011.58200K562CSTF2
XAB2ENSG00000076924.72125.416101609.035100.401406.294004.43540K562DDX21
XAB2ENSG00000076924.7966.40520690.753200.484406.186804.20920K562DDX27
XAB2ENSG00000076924.71673.042201346.206100.313503.113001.70480K562DDX6
XAB2ENSG00000076924.72874.094402341.014100.295902.144801.38480K562DKC1
XAB2ENSG00000076924.71353.09260646.756501.064907.933406.31780K562EFTUD2
XAB2ENSG00000076924.7489.70240367.106300.415602.720501.93000K562EIF3G
XAB2ENSG00000076924.71572.825501249.342600.332103.020601.79740K562EIF4B
XAB2ENSG00000076924.71614.764001210.956800.415105.321603.42080K562EWSR1
XAB2ENSG00000076924.71279.09980895.845700.513705.237504.04520K562FIP1L1
XAB2ENSG00000076924.7998.657901442.67970-0.530705.002804.22370K562FXR1
XAB2ENSG00000076924.762.59910340.26580-2.442404.400003.46390K562G3BP2
XAB2ENSG00000076924.7957.04450738.269700.374302.783701.98720K562GPKOW
XAB2ENSG00000076924.72516.700501671.994100.589902.667401.47660K562HNRNPA2B1
XAB2ENSG00000076924.71616.05360686.419001.235205.740404.03240K562IGF2BP2
XAB2ENSG00000076924.71065.11560698.041400.609505.780303.94940K562IGF2BP3
XAB2ENSG00000076924.73166.594902308.919200.455605.272704.05770K562KIF1C
XAB2ENSG00000076924.7408.02120630.49320-0.627803.844002.73030K562KRR1
XAB2ENSG00000076924.71143.85410721.053900.665608.498606.98560K562MAGOH
XAB2ENSG00000076924.73119.027802210.362900.496703.485802.23370K562MAK16
XAB2ENSG00000076924.73498.603302586.600100.435604.314503.13200K562MBNL1
XAB2ENSG00000076924.7915.43450720.650200.345102.414101.59960K562METAP2
XAB2ENSG00000076924.71055.55100638.321200.725502.633901.38470K562NONO
XAB2ENSG00000076924.72178.510101896.291700.200102.818602.06600K562NSUN2
XAB2ENSG00000076924.72997.419501462.908001.034807.052205.22800K562PABPN1
XAB2ENSG00000076924.71147.18960704.991100.7023010.200707.59830K562PCBP1
XAB2ENSG00000076924.71407.476301017.055000.468604.201303.16180K562PPIG
XAB2ENSG00000076924.72738.692201739.614900.654602.874801.39200K562PPP1R8
XAB2ENSG00000076924.71115.60220629.379600.825703.621002.76220K562PRPF8
XAB2ENSG00000076924.71113.37250889.116200.324402.336701.51160K562PSIP1
XAB2ENSG00000076924.7880.37070700.574800.329502.515401.87810K562PTBP1
XAB2ENSG00000076924.72124.765102620.34400-0.302502.097701.38660K562PUF60
XAB2ENSG00000076924.71900.724902787.67370-0.552507.507505.67810K562PUM1
XAB2ENSG00000076924.74268.948302157.441100.9845014.6273013.41700K562PUS1
XAB2ENSG00000076924.73360.428302102.432900.676505.892905.05500K562RBM15
XAB2ENSG00000076924.7593.34090353.085700.748702.712801.86680K562SF3B4
XAB2ENSG00000076924.71075.22380769.346500.482804.301702.94020K562SRFBP1
XAB2ENSG00000076924.71058.65030628.891700.751203.237501.44910K562SRP68
XAB2ENSG00000076924.71117.20890686.835700.701806.092405.05100K562SRSF1
XAB2ENSG00000076924.71599.885901087.706000.556606.922505.13600K562SRSF4
XAB2ENSG00000076924.71168.31140648.760500.8486011.947709.61740K562SRSF5
XAB2ENSG00000076924.71699.132401435.799800.242802.546201.42720K562SRSF7
XAB2ENSG00000076924.71044.607501356.02930-0.376403.798202.83500K562SYNCRIP
XAB2ENSG00000076924.71445.55680695.039001.056407.220406.01960K562TARDBP
XAB2ENSG00000076924.71398.66330670.465501.0607013.8277011.87670K562TIA1
XAB2ENSG00000076924.71392.97450658.123901.081606.836204.92820K562TRA2A
XAB2ENSG00000076924.71353.63520908.925400.574503.417602.34550K562TRIM56
XAB2ENSG00000076924.71024.61190644.636600.668402.475701.51840K562UCHL5
XAB2ENSG00000076924.73392.177302187.825200.632603.541402.01900K562UTP18
XAB2ENSG00000076924.71530.856601789.07260-0.224902.655201.82470K562WDR43
XAB2ENSG00000076924.71157.18830656.861900.816903.817102.31490K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for XAB2 is not available on ENCORE database.





10 RBPs can affect the splicing of XAB2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEXAB2ENSG00000076924.7chr19-768861676887687688055768817576891867689331-0.086000.000020.00034excludedK562AQR
SEXAB2ENSG00000076924.7chr19-768861676887687688055768817576891867689331-0.059000.000980.03890excludedK562FXR1
A3SSXAB2ENSG00000076924.7chr19-7688055768821576880557688175768861676887680.089000.000020.00020longerK562AQR
A3SSXAB2ENSG00000076924.7chr19-7689186768943176891867689331769076576908970.072000.000000.00000longerK562AQR
A3SSXAB2ENSG00000076924.7chr19-7693035769325376930357693184769436276944510.098000.000000.00000longerK562AQR
RIXAB2ENSG00000076924.7chr19-7690765769115676907657690930769102176911560.157000.002380.08822includedHepG2BCCIP
RIXAB2ENSG00000076924.7chr19-7690765769115676907657690930769102176911560.115000.000000.00000includedK562PUS1
RIXAB2ENSG00000076924.7chr19-7690765769115676907657690930769102176911560.177000.000000.00003includedHepG2U2AF2
RIXAB2ENSG00000076924.7chr19-7690765769115676907657690930769102176911560.163000.003070.03667includedHepG2PRPF8
RIXAB2ENSG00000076924.7chr19-7690765769115676907657690930769102176911560.116000.000690.01079includedK562PRPF8
RIXAB2ENSG00000076924.7chr19-769076576911567690765769093076910217691156-0.099000.004750.08397excludedHepG2FTO
RIXAB2ENSG00000076924.7chr19-7690765769115676907657690930769102176911560.307000.003890.04864includedK562U2AF2
RIXAB2ENSG00000076924.7chr19-7685160768555576851607685332768543276855550.069000.004200.03924includedHepG2RBM22
RIXAB2ENSG00000076924.7chr19-7690765769115676907657690930769102176911560.068000.000030.00080includedK562UTP18
RIXAB2ENSG00000076924.7chr19-7690765769115676907657690930769102176911560.125000.000160.00270includedK562EFTUD2
RIXAB2ENSG00000076924.7chr19-7690765769115676907657690930769102176911560.148000.000000.00001includedK562AQR
RIXAB2ENSG00000076924.7chr19-7685160768555576851607685332768543276855550.117000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for XAB2 is not avaliable on ENCORE database.