WDR12

General Information

Gene Name       : WDR12
Gene ID             : ENSG00000138442.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: WDR12)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WDR12ENSG00000138442.954.0052.6253.31ENCSR000AEF
HepG2WDR12ENSG00000138442.974.7299.1386.92ENCSR985KAT
K562WDR12ENSG00000138442.998.8798.7298.80ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WDR12 is not avaliable on ENCORE database.



Proteins bound to RNA
  • WDR12 RNA is bound by 18 proteins.  







eCLIP assay for WDR12 is not avaliable on ENCORE database.





18 proteins are bound to WDR12 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2203745360203745424-3'-UTR,intron-Distal5.202235.25980HepG2SUB1
chr2203776196203776219-5'-UTR,CDS,intron-Distal3.3663510.89609K562YBX3
chr2203776219203776225-5'-UTR,intron-Distal3.122778.44084K562YBX3
chr2203776175203776329-5'-UTR,CDS,intron-Distal3.667947.77981K562GEMIN5
chr2203776225203776288-5'-UTR,intron-Distal3.1830410.58200K562YBX3
chr2203757354203757408-CDS,intron-Distal,intron-Proximal5.4901610.65697K562UCHL5
chr2203776190203776196-CDS,intron-Distal3.1389410.35731K562YBX3
chr2203764282203764359-CDS,intron-Distal3.852478.10680HepG2GRWD1
chr2203765747203765798-CDS,intron-Distal,intron-Proximal3.756576.18214HepG2GRWD1
chr2203757335203757364-CDS,intron-Distal,intron-Proximal3.466167.63733HepG2PPIG
chr2203749216203749260-CDS,intron-Distal,intron-Proximal3.200197.50227HepG2BCLAF1
chr2203749121203749176-CDS,intron-Distal,intron-Proximal3.065155.60276HepG2BCLAF1
chr2203757339203757357-CDS,intron-Distal,intron-Proximal3.544413.79741HepG2GRWD1
chr2203747437203747482-CDS,intron-Distal3.517934.13746HepG2PPIG
chr2203745618203745679-CDS,intron-Distal3.717196.77200HepG2U2AF2
chr2203764253203764284-CDS,intron-Distal,intron-Proximal3.093117.43909HepG2BCLAF1
chr2203749210203749270-CDS,intron-Distal,intron-Proximal3.291109.02813HepG2U2AF2
chr2203757307203757426-CDS,intron-Distal,intron-Proximal4.387263.84574HepG2TRA2A
chr2203749125203749172-CDS,intron-Distal,intron-Proximal3.147445.21025HepG2PPIG
chr2203757274203757343-CDS,intron-Distal,intron-Proximal3.596404.88100K562AQR
chr2203764286203764395-CDS,intron-Distal,intron-Proximal5.304364.65563K562AQR
chr2203757331203757378-CDS,intron-Distal,intron-Proximal3.6704413.41578HepG2BUD13
chr2203760721203760792-CDS,intron-Distal,intron-Proximal4.951778.81516K562KHSRP
chr2203762080203762138-CDS,intron-Distal4.045719.50935HepG2BCLAF1
chr2203764291203764352-CDS,intron-Distal3.120228.30744HepG2BCLAF1
chr2203762086203762137-CDS,intron-Distal3.311073.99908K562BUD13
chr2203772600203772666-CDS,intron-Distal3.904923.11282HepG2G3BP1
chr2203749210203749259-CDS,intron-Distal,intron-Proximal3.099805.26696K562UCHL5
chr2203749213203749258-CDS,intron-Distal3.849949.86479HepG2PPIG
chr2203772598203772661-CDS,intron-Distal3.512877.74581HepG2BCLAF1
chr2203757357203757414-CDS,intron-Distal,intron-Proximal3.009454.64208HepG2GRWD1
chr2203748927203748965-CDS,intron-Distal,intron-Proximal4.437704.97342HepG2PPIG
chr2203748890203748945-CDS,intron-Distal,intron-Proximal4.594719.43475HepG2PRPF8
chr2203760835203760928-CDS,intron-Distal3.9136313.45280HepG2BCLAF1
chr2203765670203765752-CDS,intron-Distal,intron-Proximal4.710818.69247K562AQR
chr2203764252203764275-CDS,intron-Distal,intron-Proximal3.398433.90826K562ZNF622
chr2203757362203757427-CDS,intron-Distal,intron-Proximal3.050898.78789K562ZNF622
chr2203764275203764358-CDS,intron-Distal,intron-Proximal6.0425813.75753K562ZNF622
chr2203760840203760940-CDS,intron-Distal3.176285.00109HepG2GRWD1
chr2203748926203748967-CDS,intron-Distal,intron-Proximal3.568364.49887K562ZNF622
chr2203772600203772697-CDS,intron-Distal,intron-Proximal3.679553.99908K562BUD13
chr2203749230203749259-CDS,intron-Distal,intron-Proximal3.325376.91257HepG2BUD13
chr2203760771203760835-CDS,intron-Distal,intron-Proximal4.694757.97334HepG2BCLAF1
chr2203765801203765849-CDS,intron-Distal,intron-Proximal3.637114.36528HepG2U2AF2
chr2203749164203749258-CDS,intron-Distal3.346986.83963HepG2GRWD1
chr2203760659203760746-intron-Distal,intron-Proximal4.6271410.39215K562PRPF8
chr2203763581203763671-intron-Distal3.456165.86976HepG2ILF3
chr2203757298203757331-intron-Distal,intron-Proximal4.074775.01214HepG2BUD13
chr2203757738203757816-intron-Distal3.192284.89503HepG2KHSRP
chr2203757725203757834-intron-Distal4.665396.94732K562KHSRP
chr2203767041203767168-intron-Distal4.113043.45317HepG2HNRNPL
chr2203768141203768196-intron-Distal3.294033.59803HepG2PTBP1
chr2203772420203772505-intron-Distal,intron-Proximal3.917293.48768HepG2KHSRP
chr2203757271203757330-intron-Distal,intron-Proximal4.370884.96658K562KHSRP
chr2203757183203757271-intron-Distal,intron-Proximal4.075787.26586K562KHSRP
chr2203768136203768191-intron-Distal3.359093.32861HepG2U2AF2
chr2203757277203757333-intron-Distal,intron-Proximal4.707364.02817HepG2PRPF8
chr2203765668203765721-intron-Distal,intron-Proximal4.238343.89565K562PRPF8
chr2203757201203757253-intron-Distal,intron-Proximal4.158494.29306HepG2KHSRP
chr2203760667203760721-intron-Distal,intron-Proximal4.787397.69142K562KHSRP
chr2203757041203757088-intron-Distal4.128874.58794K562KHSRP
chr2203770578203770639-intron-Distal4.056884.21358HepG2U2AF2
chr2203759538203759585-intron-Distal,intron-Proximal5.567419.50483HepG2U2AF2
chr2203753169203753278-intron-Distal4.517478.98750HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WDR12 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WDR12 is not available on ENCORE database.

  • 105 RBPs can affect the levels of WDR12.  








The Knockdown/knockout RNA-Seq assay for WDR12 is not available on ENCORE database.





105 RBPs can affect the gene expression of WDR12 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WDR12ENSG00000138442.52021.103102694.00270-0.414607.939606.87440HepG2AUH
WDR12ENSG00000138442.51199.998801790.65930-0.577504.640203.42600HepG2BCCIP
WDR12ENSG00000138442.5767.658801556.01130-1.0193013.8302012.04540HepG2BCLAF1
WDR12ENSG00000138442.52047.257702827.75020-0.466003.316102.24070HepG2CCAR1
WDR12ENSG00000138442.51270.577402413.95000-0.9259016.0897014.60010HepG2CPSF6
WDR12ENSG00000138442.51520.281602511.47480-0.7242026.0598024.22080HepG2DAZAP1
WDR12ENSG00000138442.51325.473801689.01710-0.349704.248302.83380HepG2DDX1
WDR12ENSG00000138442.51830.344201464.939600.321202.996202.04330HepG2DDX24
WDR12ENSG00000138442.51689.157002271.32530-0.427203.515902.82020HepG2DDX3X
WDR12ENSG00000138442.51170.134902741.20280-1.2281011.808109.87800HepG2DDX59
WDR12ENSG00000138442.51210.001101950.86600-0.689106.889605.94980HepG2DDX6
WDR12ENSG00000138442.51195.425501597.37910-0.418204.080202.90460HepG2DHX30
WDR12ENSG00000138442.51290.691001656.19700-0.359704.522703.64020HepG2DNAJC21
WDR12ENSG00000138442.51229.987601641.47970-0.416407.993406.95620HepG2DNAJC2
WDR12ENSG00000138442.5790.393001875.66230-1.2468022.6877021.09960HepG2EIF2S1
WDR12ENSG00000138442.51526.542902072.94710-0.441403.185902.50040HepG2EIF4A3
WDR12ENSG00000138442.51961.054202373.53480-0.275402.025701.32130HepG2EIF4G2
WDR12ENSG00000138442.52602.933503093.07190-0.248903.118202.48580HepG2ETF1
WDR12ENSG00000138442.5866.031601066.10070-0.299902.389401.30630HepG2FAM120A
WDR12ENSG00000138442.51126.747801940.04300-0.783909.366508.17800HepG2G3BP1
WDR12ENSG00000138442.51084.185101540.86930-0.507104.821103.47390HepG2GNB2L1
WDR12ENSG00000138442.51773.127702736.52340-0.626006.703805.73530HepG2GPKOW
WDR12ENSG00000138442.5888.754601672.06270-0.9118016.3536014.99250HepG2HNRNPA1
WDR12ENSG00000138442.51937.376802308.14160-0.252602.902901.94870HepG2HNRNPA2B1
WDR12ENSG00000138442.51085.729201859.83000-0.7765012.2002010.83450HepG2HNRNPC
WDR12ENSG00000138442.51432.259802216.71980-0.6301015.3437013.83260HepG2HNRNPF
WDR12ENSG00000138442.51856.187902287.74610-0.301605.212004.31170HepG2HNRNPL
WDR12ENSG00000138442.51401.218202611.50360-0.8982014.7051013.41060HepG2HNRNPLL
WDR12ENSG00000138442.51014.061201519.16490-0.583103.468602.41120HepG2HNRNPM
WDR12ENSG00000138442.51236.470101847.53620-0.5794013.0048011.76900HepG2HNRNPU
WDR12ENSG00000138442.51389.094102182.83610-0.6521011.6224010.23620HepG2IGF2BP1
WDR12ENSG00000138442.51571.753301972.07910-0.327302.256201.63910HepG2IGF2BP2
WDR12ENSG00000138442.51484.958401887.20230-0.345806.494905.41820HepG2ILF2
WDR12ENSG00000138442.52306.713202984.89680-0.371802.373201.60770HepG2LARP4
WDR12ENSG00000138442.52895.322102103.649800.460703.829903.09750HepG2MATR3
WDR12ENSG00000138442.51839.781702663.12540-0.533603.618102.49950HepG2MTPAP
WDR12ENSG00000138442.51916.250402490.37600-0.378104.997803.97640HepG2NOL12
WDR12ENSG00000138442.51510.395301917.83000-0.344502.367701.69530HepG2PABPC4
WDR12ENSG00000138442.51317.963401647.86000-0.322303.682702.84460HepG2PPIL4
WDR12ENSG00000138442.51789.394202071.12040-0.210902.236801.73480HepG2PTBP1
WDR12ENSG00000138442.51683.485402377.29570-0.497906.348605.49490HepG2PUF60
WDR12ENSG00000138442.51922.845202521.76710-0.391204.996004.10860HepG2PUM2
WDR12ENSG00000138442.51360.556901560.87650-0.198202.001701.45890HepG2PUS1
WDR12ENSG00000138442.51878.601702243.10130-0.255802.585001.97750HepG2QKI
WDR12ENSG00000138442.51802.988402304.96860-0.354405.523004.80120HepG2NELFE
WDR12ENSG00000138442.51834.581102146.74610-0.226702.613202.01200HepG2RECQL
WDR12ENSG00000138442.51490.713202387.95020-0.6798010.406109.22760HepG2RPLP0
WDR12ENSG00000138442.51433.717401645.33070-0.198602.126201.54850HepG2SAFB2
WDR12ENSG00000138442.51891.826002584.94360-0.450404.821303.91130HepG2SF3B1
WDR12ENSG00000138442.51113.488702156.32620-0.9535031.6414030.03140HepG2SF3B4
WDR12ENSG00000138442.51612.113902279.48910-0.4998012.4130011.10870HepG2SLBP
WDR12ENSG00000138442.51217.779102876.17760-1.2399014.8347013.04620HepG2SNRNP70
WDR12ENSG00000138442.53006.109602250.728500.417408.787608.05160HepG2SRSF1
WDR12ENSG00000138442.51959.361902347.25260-0.260603.319302.64500HepG2SRSF5
WDR12ENSG00000138442.51315.554802177.85390-0.7272020.0155018.45360HepG2SRSF7
WDR12ENSG00000138442.52235.284402535.19360-0.181602.051601.59370HepG2SSB
WDR12ENSG00000138442.52210.474602669.45620-0.272204.355703.60910HepG2SUCLG1
WDR12ENSG00000138442.51053.784301486.97530-0.496802.292901.43130HepG2SUPT6H
WDR12ENSG00000138442.5961.248501752.66140-0.8666010.130708.97180HepG2SUPV3L1
WDR12ENSG00000138442.51718.678702545.08140-0.566406.511805.46180HepG2TARDBP
WDR12ENSG00000138442.51480.002201858.90410-0.328903.296602.38820HepG2TIA1
WDR12ENSG00000138442.51178.722201795.34170-0.607009.942309.09770HepG2TIAL1
WDR12ENSG00000138442.51378.612701811.26720-0.393806.540005.73870HepG2TRIM56
WDR12ENSG00000138442.51504.913301841.87820-0.291504.056203.23550HepG2UPF1
WDR12ENSG00000138442.51035.045201605.05050-0.632904.206402.95460HepG2UPF2
WDR12ENSG00000138442.52543.239201778.265800.5161012.1911011.07020HepG2UTP3
WDR12ENSG00000138442.51336.853401725.30120-0.368002.443501.75800HepG2XRN2
WDR12ENSG00000138442.51255.831101821.53560-0.5365012.6850011.41700HepG2ZC3H8
WDR12ENSG00000138442.51525.231402025.71780-0.409408.909108.07070HepG2ZNF622
WDR12ENSG00000138442.51714.444603416.61760-0.9948021.8496020.37880K562AQR
WDR12ENSG00000138442.51777.269802160.70880-0.281803.304601.84470K562BCCIP
WDR12ENSG00000138442.51344.313302088.06080-0.6353015.9549013.61090K562BCLAF1
WDR12ENSG00000138442.51930.865102927.98800-0.600703.618202.62090K562BOP1
WDR12ENSG00000138442.51819.452202331.12200-0.357503.272801.86440K562CIRBP
WDR12ENSG00000138442.52828.098604604.39990-0.703203.227002.06570K562CNOT7
WDR12ENSG00000138442.51753.359303113.42980-0.828408.288306.91860K562CPSF6
WDR12ENSG00000138442.52000.863202439.59700-0.286003.783202.36170K562DDX21
WDR12ENSG00000138442.51063.656101390.91950-0.387003.850602.59460K562DDX3X
WDR12ENSG00000138442.54532.104803701.488500.292004.859104.02980K562DDX47
WDR12ENSG00000138442.52760.120302280.252600.275403.244802.28620K562DKC1
WDR12ENSG00000138442.51168.636401857.18240-0.668308.073406.44520K562EFTUD2
WDR12ENSG00000138442.51741.300502816.95140-0.6940017.9962016.39360K562EIF2S2
WDR12ENSG00000138442.51400.832301988.71610-0.505603.858402.61330K562EIF3D
WDR12ENSG00000138442.52166.829701790.011300.275502.682001.89690K562EIF3G
WDR12ENSG00000138442.51112.916801453.09980-0.384803.525002.60200K562EIF4A3
WDR12ENSG00000138442.53672.804804389.61910-0.257202.436601.55160K562EIF4G2
WDR12ENSG00000138442.52552.650703197.69100-0.325003.001502.11600K562FIP1L1
WDR12ENSG00000138442.51796.328803167.57290-0.818307.996706.49760K562FMR1
WDR12ENSG00000138442.51574.799802684.68740-0.769607.719706.11220K562FTO
WDR12ENSG00000138442.52120.059701511.151000.488407.374206.45060K562FXR1
WDR12ENSG00000138442.52238.246001754.323500.351402.026001.43340K562G3BP2
WDR12ENSG00000138442.51538.503002972.67000-0.9502010.367508.81320K562GPKOW
WDR12ENSG00000138442.52630.392003753.88050-0.513107.721006.44520K562GRSF1
WDR12ENSG00000138442.51908.179202404.96460-0.333803.510102.29340K562HNRNPA1
WDR12ENSG00000138442.5964.675802111.91000-1.1304012.2967011.11320K562HNRNPC
WDR12ENSG00000138442.52842.790302172.300900.388003.299401.93650K562HNRNPK
WDR12ENSG00000138442.52154.449002663.35800-0.305903.750202.70820K562HNRNPU
WDR12ENSG00000138442.51631.406102175.16300-0.415002.966501.89330K562IGF2BP2
WDR12ENSG00000138442.51761.609102537.99910-0.526803.131302.13080K562KRR1
WDR12ENSG00000138442.51845.611602285.88010-0.308702.756201.91780K562MAGOH
WDR12ENSG00000138442.51846.261702901.61090-0.652205.656704.37610K562METAP2
WDR12ENSG00000138442.51893.524902651.79280-0.4859011.275809.76300K562MTPAP
WDR12ENSG00000138442.52338.735502946.52730-0.333307.733806.57380K562NSUN2
WDR12ENSG00000138442.51768.220302343.40560-0.406303.307102.39830K562PCBP3
WDR12ENSG00000138442.51414.734701797.49460-0.345503.481502.57680K562POLR2G
WDR12ENSG00000138442.51373.441301893.44830-0.463203.480702.45080K562PSIP1
WDR12ENSG00000138442.53291.740004789.53100-0.541004.912203.82870K562PUF60
WDR12ENSG00000138442.54154.620004991.55700-0.264802.494301.58110K562PUM2
WDR12ENSG00000138442.51593.353602129.49260-0.418404.202303.14080K562RBM22
WDR12ENSG00000138442.52244.949602907.25130-0.373006.189505.00780K562SF3A3
WDR12ENSG00000138442.51623.998302826.71130-0.799605.839004.39230K562SF3B1
WDR12ENSG00000138442.5945.050801824.98190-0.9494017.9996015.64870K562SF3B4
WDR12ENSG00000138442.51254.636801637.24090-0.384002.637201.64320K562SRFBP1
WDR12ENSG00000138442.52531.906202978.52200-0.234403.786602.71060K562SRPK2
WDR12ENSG00000138442.51692.490302177.20160-0.363305.440103.78070K562SRSF7
WDR12ENSG00000138442.53023.069103837.59620-0.344202.765801.51680K562STAU1
WDR12ENSG00000138442.51128.626001750.11150-0.632906.211804.64570K562SUPV3L1
WDR12ENSG00000138442.52481.537101802.902700.460805.973004.75740K562SYNCRIP
WDR12ENSG00000138442.51425.205502203.46000-0.628607.882006.61110K562TARDBP
WDR12ENSG00000138442.51675.400202125.49430-0.343303.583202.63350K562TIA1
WDR12ENSG00000138442.51362.587301821.23920-0.418602.944201.97740K562TIAL1
WDR12ENSG00000138442.51688.272002085.81680-0.305102.534301.49930K562TRA2A
WDR12ENSG00000138442.52841.004603741.13040-0.397103.805302.10500K562TRIP6
WDR12ENSG00000138442.51337.203001756.88640-0.393804.504203.48430K562U2AF2
WDR12ENSG00000138442.51268.266501852.12410-0.546305.508904.02440K562UCHL5
WDR12ENSG00000138442.52130.657803124.25370-0.5522012.0934010.72310K562UPF1
WDR12ENSG00000138442.51854.610802673.34420-0.527507.805806.28910K562WDR3
WDR12ENSG00000138442.52924.086403849.10860-0.396504.516103.37070K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WDR12 is not available on ENCORE database.





8 RBPs can affect the splicing of WDR12 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEWDR12ENSG00000138442.5chr2-203762022203762155203760787203760942203764253203764396-0.051000.000520.00704excludedK562AQR
SEWDR12ENSG00000138442.5chr2-203759303203759349203757339203757425203760787203760942-0.056000.000000.00000excludedK562AQR
SEWDR12ENSG00000138442.5chr2-203759303203759341203757339203757425203760787203760942-0.123000.000040.00232excludedHepG2SF3A3
RIWDR12ENSG00000138442.5chr2-2037489202037492582037489202037490262037491172037492580.086000.001810.04071includedHepG2FTO
MXEWDR12ENSG00000138442.5chr2-2037620222037621382037642532037643602037607202037609422037657472037658430.103000.002720.045801includedHepG2U2AF1
MXEWDR12ENSG00000138442.5chr2-203764253203764360203765747203765842203760787203760942203772587203772682-0.063000.000360.003772includedK562AQR
MXEWDR12ENSG00000138442.5chr2-203760787203760938203762022203762138203757339203757425203764253203764360-0.069000.000000.000002includedK562AQR
MXEWDR12ENSG00000138442.5chr2-203760787203760942203762022203762138203757339203757425203764253203764360-0.119000.000000.000002includedK562AQR
MXEWDR12ENSG00000138442.5chr2-2037620222037621382037642532037643602037607872037609422037657472037658420.153000.000000.000961includedK562AARS
MXEWDR12ENSG00000138442.5chr2-203762022203762138203764253203764360203760787203760942203765747203765842-0.087000.001500.090512includedK562CPSF6
MXEWDR12ENSG00000138442.5chr2-2037620222037621382037642532037643602037607872037609422037657472037658420.234000.000020.002081includedK562PPIL4
MXEWDR12ENSG00000138442.5chr2-2037620222037621382037642532037643602037607872037609422037657472037658420.222000.000000.000031includedK562DDX55

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WDR12 is not avaliable on ENCORE database.