TPRN

General Information

Gene Name       : TPRN
Gene ID             : ENSG00000176058.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TPRN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TPRNENSG00000176058.120.051.350.70ENCSR000AEF
HepG2TPRNENSG00000176058.1211.241.806.52ENCSR985KAT
K562TPRNENSG00000176058.129.012.945.97ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TPRN is not avaliable on ENCORE database.



Proteins bound to RNA
  • TPRN RNA is bound by 13 proteins.  







eCLIP assay for TPRN is not avaliable on ENCORE database.





13 proteins are bound to TPRN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9140086142140086480-3'-UTR,intron-Distal4.6566111.97446HepG2AKAP1
chr9140086258140086387-3'-UTR,intron-Distal4.8235312.76496HepG2UPF1
chr9140086387140086476-3'-UTR,intron-Distal3.636013.97153HepG2UPF1
chr9140086300140086359-3'-UTR,intron-Distal4.456257.02726HepG2DDX55
chr9140086154140086395-3'-UTR,intron-Distal4.5951410.21308K562UPF1
chr9140086170140086258-3'-UTR,intron-Distal5.049418.87118HepG2UPF1
chr9140095110140095175-5'-UTR,CDS,intron-Distal4.107677.12467HepG2DDX3X
chr9140088707140088769-intron-Distal3.408795.45050HepG2CSTF2T
chr9140089537140089610-intron-Distal,intron-Proximal4.189737.34629HepG2CSTF2T
chr9140087285140087371-intron-Distal4.800007.45950HepG2PRPF4
chr9140089538140089608-intron-Distal,intron-Proximal4.283674.48497K562NONO
chr9140089538140089594-intron-Distal,intron-Proximal3.745363.14687K562CSTF2T
chr9140093024140093079-intron-Distal4.442574.23759K562NONO
chr9140093262140093313-intron-Distal4.260603.44758HepG2CSTF2T
chr9140093026140093077-intron-Distal3.031354.68402HepG2CSTF2T
chr9140090408140090461-intron-Distal3.527315.16304HepG2CSTF2T
chr9140092220140092296-intron-Distal3.938246.10842HepG2CSTF2T
chr9140088712140088753-intron-Distal3.732454.76224HepG2NKRF
chr9140090140140090235-intron-Distal3.005844.30413HepG2CSTF2T
chr9140089468140089588-intron-Distal3.563439.11228HepG2NKRF
chr9140092774140092840-intron-Distal4.665886.37044HepG2NKRF
chr9140093215140093262-intron-Distal4.401895.16036HepG2CSTF2T
chr9140089181140089224-intron-Distal4.406954.15139HepG2NKRF
chr9140089171140089237-intron-Distal3.099636.84294HepG2CSTF2T
chr9140089418140089465-intron-Distal3.320396.13981HepG2CSTF2T
chr9140090514140090599-intron-Distal4.777913.17679K562DDX52
chr9140091331140091435-intron-Distal4.368385.08856K562ILF3
chr9140088346140088437-intron-Distal3.422684.85104HepG2NKRF
chr9140089537140089623-intron-Distal,intron-Proximal4.051295.44474HepG2FAM120A
chr9140089131140089171-intron-Distal3.764805.32871HepG2CSTF2T
chr9140089393140089472-intron-Distal3.787035.16644HepG2FAM120A
chr9140089174140089225-intron-Distal3.859453.48722HepG2PRPF4
chr9140089162140089236-intron-Distal4.276454.75311K562CSTF2T
chr9140093017140093086-intron-Distal4.568765.63746K562EWSR1
chr9140090670140090711-intron-Distal4.158834.10564HepG2CSTF2T
chr9140087445140087491-intron-Distal4.151513.94684HepG2CSTF2T
chr9140098730140098782-3'-UTR,intron-Distal,intron-Proximal3.035325.04681K562YBX3
chr9140090506140090571-intron-Distal3.221463.14365K562NONO
chr9140092889140092937-intron-Distal4.151513.94684HepG2CSTF2T
chr9140090516140090585-intron-Distal3.355486.09076HepG2NKRF
chr9140091410140091476-intron-Distal3.401053.58557HepG2ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TPRN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TPRN is not available on ENCORE database.

  • 91 RBPs can affect the levels of TPRN.  








The Knockdown/knockout RNA-Seq assay for TPRN is not available on ENCORE database.





91 RBPs can affect the gene expression of TPRN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TPRNENSG00000176058.777.94020171.99900-1.142005.074603.66480HepG2AATF
TPRNENSG00000176058.7341.33690506.90040-0.570504.625603.87770HepG2ACO1
TPRNENSG00000176058.7211.20400661.91830-1.648002.238901.75580HepG2AKAP1
TPRNENSG00000176058.7646.46230529.149900.288802.156501.53670HepG2AUH
TPRNENSG00000176058.7307.02880200.519400.614502.674701.75530HepG2BCCIP
TPRNENSG00000176058.7305.55520174.238100.810304.641703.50150HepG2BCLAF1
TPRNENSG00000176058.7121.86180222.38460-0.867804.617003.65110HepG2CALR
TPRNENSG00000176058.7201.03960107.250600.906403.226002.12470HepG2YBX3
TPRNENSG00000176058.780.33680176.22290-1.133303.273701.75570HepG2CSTF2T
TPRNENSG00000176058.7316.74560211.893300.579904.139303.26120HepG2DAZAP1
TPRNENSG00000176058.7114.96080185.66090-0.691502.881101.94670HepG2DDX24
TPRNENSG00000176058.7185.49940105.314500.816604.344503.47960HepG2DNAJC21
TPRNENSG00000176058.7240.64620104.381001.2050011.170409.95820HepG2DNAJC2
TPRNENSG00000176058.7107.19390174.68740-0.704602.338701.32770HepG2AGO1
TPRNENSG00000176058.71053.88070523.399601.009603.601902.92940HepG2EIF2S1
TPRNENSG00000176058.797.47530171.68310-0.816603.226102.25510HepG2EIF3D
TPRNENSG00000176058.7470.60590200.250101.2326013.6830011.96650HepG2EIF4G2
TPRNENSG00000176058.7115.79610180.70020-0.642002.596501.48440HepG2FASTKD2
TPRNENSG00000176058.7235.21400419.49290-0.834707.335906.09300HepG2FUBP3
TPRNENSG00000176058.7416.36200216.758300.9417011.005109.70090HepG2HNRNPF
TPRNENSG00000176058.7166.10690117.482200.499601.869801.36260HepG2HNRNPU
TPRNENSG00000176058.7477.30120213.446601.1609015.1768013.62530HepG2IGF2BP1
TPRNENSG00000176058.773.25160179.67070-1.294404.403203.09440HepG2METAP2
TPRNENSG00000176058.7292.40500210.112700.476702.521201.79520HepG2NOL12
TPRNENSG00000176058.7241.60860132.244100.869403.762002.08990HepG2NOLC1
TPRNENSG00000176058.7331.13320181.029600.871103.764402.47280HepG2NONO
TPRNENSG00000176058.7425.00560177.431501.260102.911501.99980HepG2PABPC1
TPRNENSG00000176058.7255.40200104.784901.285208.457007.21770HepG2PPIL4
TPRNENSG00000176058.7245.04260152.093200.688002.610701.82420HepG2PRPF8
TPRNENSG00000176058.7717.54870200.570001.8389036.5551034.69690HepG2PUF60
TPRNENSG00000176058.7339.38110212.912800.672505.567104.78710HepG2PUM1
TPRNENSG00000176058.7374.22690636.24100-0.765701.946201.40780HepG2QKI
TPRNENSG00000176058.7306.34750159.073600.945404.734303.33710HepG2RCC2
TPRNENSG00000176058.7333.58700233.478100.514702.932902.23230HepG2RPLP0
TPRNENSG00000176058.7324.69000180.638500.845904.428203.42810HepG2RPS2
TPRNENSG00000176058.7242.49270104.623801.2126010.490309.35960HepG2SAFB2
TPRNENSG00000176058.7715.69200471.189400.602903.791902.99740HepG2SF3A3
TPRNENSG00000176058.7253.12590348.62290-0.461801.936401.33950HepG2SF3B1
TPRNENSG00000176058.7426.94260192.313001.1505015.8311014.40710HepG2SLBP
TPRNENSG00000176058.7197.35550122.010100.693703.601002.88350HepG2SMN1
TPRNENSG00000176058.7280.98220638.47810-1.184207.739507.04100HepG2SRSF1
TPRNENSG00000176058.7413.83620212.952400.958406.126505.15540HepG2SRSF7
TPRNENSG00000176058.7841.12390497.953200.7562012.7135011.77270HepG2SSB
TPRNENSG00000176058.7341.38840225.218500.600004.370003.62230HepG2SUCLG1
TPRNENSG00000176058.7100.67550574.03160-2.5114018.8713017.59630HepG2TAF15
TPRNENSG00000176058.7235.43920114.160201.044204.640504.02750HepG2TIAL1
TPRNENSG00000176058.7193.43340115.176100.747904.173903.50940HepG2TRIM56
TPRNENSG00000176058.7299.04720195.946500.609802.051101.30990HepG2TUFM
TPRNENSG00000176058.7559.26780207.405101.4310014.4018012.45950HepG2UBE2L3
TPRNENSG00000176058.7181.74660115.939900.648502.684401.93650HepG2UCHL5
TPRNENSG00000176058.7543.77510417.872800.379803.038602.31420HepG2UPF1
TPRNENSG00000176058.7404.17730193.199201.064808.074406.84760HepG2XRN2
TPRNENSG00000176058.7549.76840459.580400.258401.785901.32070HepG2ZNF622
TPRNENSG00000176058.7654.72150477.198500.456202.589901.39120K562APOBEC3C
TPRNENSG00000176058.7754.10280564.751800.417002.786002.19590K562AQR
TPRNENSG00000176058.7352.38990193.880300.861907.349605.75890K562BCLAF1
TPRNENSG00000176058.7269.33390147.087200.872605.004203.51790K562CSTF2
TPRNENSG00000176058.7515.54940665.17340-0.367602.632701.68200K562CELF1
TPRNENSG00000176058.7388.63510274.795000.500003.158002.03940K562DDX3X
TPRNENSG00000176058.7774.66850403.540300.9408016.9516015.45700K562DDX47
TPRNENSG00000176058.7371.12270162.423501.1920010.217508.35590K562EFTUD2
TPRNENSG00000176058.7442.64750212.613501.057806.346804.77230K562EIF3A
TPRNENSG00000176058.7336.42080173.833000.952505.857204.27190K562EIF3D
TPRNENSG00000176058.7194.2266090.728201.098006.492905.28870K562EIF3G
TPRNENSG00000176058.7796.82170540.837000.559005.456404.15750K562EIF4G2
TPRNENSG00000176058.7394.61840240.003300.717305.640003.78740K562EXOSC5
TPRNENSG00000176058.7379.08060239.851500.660304.422503.33250K562FIP1L1
TPRNENSG00000176058.7382.45520298.564100.357101.975801.44770K562FXR1
TPRNENSG00000176058.77.7896045.23510-2.537805.772404.66640K562G3BP2
TPRNENSG00000176058.7784.79080465.111400.754603.942503.04350K562GRSF1
TPRNENSG00000176058.7318.24280196.665800.694304.069403.36240K562HNRNPC
TPRNENSG00000176058.7730.82510478.659300.610405.465104.19650K562HNRNPU
TPRNENSG00000176058.7297.36530153.354300.955302.301001.39050K562IGF2BP2
TPRNENSG00000176058.7269.92350160.884300.746402.319401.54530K562MAGOH
TPRNENSG00000176058.7551.84280422.286500.385902.663001.77540K562MBNL1
TPRNENSG00000176058.7279.85920174.265900.683303.894002.84300K562METAP2
TPRNENSG00000176058.7342.91230160.219701.097708.095605.68850K562NONO
TPRNENSG00000176058.7250.00350143.095200.804902.387701.48230K562PCBP2
TPRNENSG00000176058.7423.77170272.292400.638004.537303.44960K562PPIG
TPRNENSG00000176058.7298.65860158.058700.917905.364404.31700K562PRPF8
TPRNENSG00000176058.7302.43440176.352400.778103.783502.70240K562PSIP1
TPRNENSG00000176058.7279.59390156.330500.838602.314301.69990K562PTBP1
TPRNENSG00000176058.7271.86550149.746600.860303.102802.20770K562RBM22
TPRNENSG00000176058.7430.50430160.947301.419304.924203.83150K562RPS19
TPRNENSG00000176058.7194.18630105.403900.881403.471202.33940K562RPS3
TPRNENSG00000176058.7379.10050208.678300.861206.897705.20200K562SAFB
TPRNENSG00000176058.792.7609046.968500.981703.313802.37670K562SF3B4
TPRNENSG00000176058.7246.43810152.613100.691203.383302.22090K562SRFBP1
TPRNENSG00000176058.7282.92080157.902700.841304.897302.66560K562SRP68
TPRNENSG00000176058.7315.48960153.288001.041205.228404.26120K562SRSF1
TPRNENSG00000176058.7209.94670101.759701.044805.478503.90450K562SRSF4
TPRNENSG00000176058.7254.60280144.848200.813602.428601.45410K562SRSF5
TPRNENSG00000176058.7183.39260358.70240-0.967903.665601.93250K562SUPT6H
TPRNENSG00000176058.7341.83650155.068501.140306.731805.58610K562TARDBP
TPRNENSG00000176058.7353.44110149.599201.240304.812203.68720K562TIA1
TPRNENSG00000176058.7268.08740146.964500.867103.305302.09240K562TRA2A
TPRNENSG00000176058.7262.27030180.300800.540502.467101.58280K562TRIM56
TPRNENSG00000176058.721.1113045.23100-1.099302.155301.44660K562U2AF2
TPRNENSG00000176058.7267.45100161.915500.723903.513002.35890K562UCHL5
TPRNENSG00000176058.7584.06380460.481500.342902.614601.91650K562UPF1
TPRNENSG00000176058.7508.55950409.740500.311602.169501.41310K562WDR43
TPRNENSG00000176058.7340.35010164.950401.044906.048304.02180K562XRN2
TPRNENSG00000176058.7165.58730352.91810-1.091704.519102.26810K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TPRN is not available on ENCORE database.





5 RBPs can affect the splicing of TPRN :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RITPRNENSG00000176058.7chr9-140086068140086817140086068140086626140086710140086817-0.193000.001960.07949excludedHepG2BCCIP
RITPRNENSG00000176058.7chr9-1400860681400868171400860681400866261400867101400868170.260000.000170.00287includedHepG2TAF15
RITPRNENSG00000176058.7chr9-1400860681400868171400860681400866261400867101400868170.178000.000940.01755includedHepG2SRSF9
RITPRNENSG00000176058.7chr9-1400860681400868171400860681400866261400867101400868170.091000.000600.00887includedHepG2HNRNPK
RITPRNENSG00000176058.7chr9-1400860681400868171400860681400866261400867101400868170.097000.000040.00032includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TPRN is not avaliable on ENCORE database.