TBKBP1

General Information

Gene Name       : TBKBP1
Gene ID             : ENSG00000198933.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TBKBP1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TBKBP1ENSG00000198933.90.070.260.17ENCSR000AEF
HepG2TBKBP1ENSG00000198933.910.335.257.79ENCSR985KAT
K562TBKBP1ENSG00000198933.98.214.576.39ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TBKBP1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TBKBP1 RNA is bound by 21 proteins.  







eCLIP assay for TBKBP1 is not avaliable on ENCORE database.





21 proteins are bound to TBKBP1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr174578887445788929+3'-UTR4.510184.90799K562UPF1
chr174578854145788644+3'-UTR5.171146.29854K562UPF1
chr174577290545772965+5'-UTR,intron-Distal5.3948311.08680HepG2PRPF4
chr174577292745772973+5'-UTR,intron-Distal4.134245.93122HepG2FASTKD2
chr174577307545773151+5'-UTR,intron-Distal5.3893735.68044HepG2CSTF2T
chr174577315545773197+5'-UTR,intron-Distal3.642485.91358HepG2FAM120A
chr174577293145773000+5'-UTR,intron-Distal3.944665.28409HepG2GTF2F1
chr174577147945771542+5'-UTR4.6066614.10047HepG2FAM120A
chr174577342945773486+5'-UTR,CDS,intron-Proximal3.121703.46866HepG2U2AF2
chr174577315145773191+5'-UTR,intron-Distal6.1366315.39233HepG2CSTF2T
chr174577277445772828+5'-UTR,intron-Distal4.715026.92157K562CSTF2T
chr174577308745773153+5'-UTR,intron-Distal5.123896.42243HepG2GTF2F1
chr174577315245773192+5'-UTR,intron-Distal4.317925.11005HepG2PRPF4
chr174577281545772865+5'-UTR,intron-Distal4.2776014.53782HepG2CSTF2T
chr174577309945773167+5'-UTR,intron-Distal3.663783.95034K562DROSHA
chr174577305245773156+5'-UTR,intron-Distal3.613977.13132K562GTF2F1
chr174577147345771558+5'-UTR3.587613.37207K562FAM120A
chr174577334045773376+5'-UTR,intron-Distal,intron-Proximal3.962687.94468HepG2PRPF4
chr174577296545773004+5'-UTR,intron-Distal4.029947.47076HepG2PRPF4
chr174577300445773046+5'-UTR,intron-Distal3.418876.71630HepG2PRPF4
chr174577331045773421+5'-UTR,intron-Distal,intron-Proximal4.3770510.03192K562CSTF2T
chr174577309445773215+5'-UTR,intron-Distal3.223785.17636HepG2DROSHA
chr174577292045772976+5'-UTR,intron-Distal5.1912220.56544HepG2CSTF2T
chr174577334945773487+5'-UTR,CDS,intron-Proximal3.256274.20336HepG2AQR
chr174577294445772997+5'-UTR,intron-Distal4.475235.49785HepG2XRN2
chr174577300745773054+5'-UTR,intron-Distal4.9106517.56917HepG2CSTF2T
chr174577148845771526+5'-UTR4.469215.20041HepG2PRPF4
chr174577334745773417+5'-UTR,intron-Proximal3.483864.12529K562GTF2F1
chr174577276545772806+5'-UTR,intron-Distal3.505118.69616HepG2CSTF2T
chr174577149745771547+5'-UTR4.866738.03474K562CSTF2T
chr174577327145773314+5'-UTR,intron-Distal4.735065.66556HepG2FASTKD2
chr174577307245773152+5'-UTR,intron-Distal3.8310014.02042HepG2PRPF4
chr174577337145773438+5'-UTR,intron-Proximal4.451524.14056K562EWSR1
chr174577276645772828+5'-UTR,intron-Distal3.300955.60393HepG2FASTKD2
chr174577336245773457+5'-UTR,intron-Proximal3.212168.71681HepG2FASTKD2
chr174577307145773148+5'-UTR,intron-Distal3.475903.94787K562AQR
chr174577276845772824+5'-UTR,intron-Distal3.209546.02920HepG2PRPF4
chr174577335145773419+5'-UTR,intron-Proximal4.0702315.95347HepG2CSTF2T
chr174577147545771552+5'-UTR4.853864.36078K562GTF2F1
chr174577306245773135+5'-UTR,intron-Distal4.936828.59041K562CSTF2T
chr174577327645773326+5'-UTR,intron-Distal4.9065018.34101HepG2CSTF2T
chr174577307845773136+5'-UTR,intron-Distal3.664679.31410HepG2FAM120A
chr174577292045772997+5'-UTR,intron-Distal5.1683516.10613HepG2FAM120A
chr174577343645773468+5'-UTR,intron-Proximal4.434255.11005HepG2PRPF4
chr174577297645773007+5'-UTR,intron-Distal5.9822112.62224HepG2CSTF2T
chr174577339745773470+5'-UTR,intron-Proximal5.009705.13952K562SF3B4
chr174577353045773589+CDS4.190594.21087HepG2GRWD1
chr174577358945773692+CDS4.642374.69889HepG2GRWD1
chr174578585345785878+CDS4.073673.20743HepG2PPIG
chr174577445945774563+CDS,intron-Proximal4.8698411.08513HepG2PPIG
chr174578614445786261+CDS4.231874.83379HepG2HNRNPK
chr174577361845773679+CDS3.747106.98305HepG2PPIG
chr174577596045776013+CDS,intron-Proximal3.685047.26626HepG2PPIG
chr174577210045772195+intron-Distal,intron-Proximal5.8817629.66138HepG2FAM120A
chr174577167945771745+intron-Distal4.366989.46556HepG2PRPF4
chr174578425345784332+intron-Distal3.261503.02891HepG2HNRNPL
chr174577223245772333+intron-Distal4.629749.65481HepG2PRPF4
chr174577213545772216+intron-Distal5.073828.86792K562CSTF2T
chr174577167645771740+intron-Distal3.780194.87547HepG2NKRF
chr174577226945772325+intron-Distal4.924545.54520K562GTF2F1
chr174578425345784339+intron-Distal5.477309.70777K562AGGF1
chr174577181745771884+intron-Distal6.8330326.63289HepG2CSTF2T
chr174577233845772398+intron-Distal4.779066.13530HepG2GTF2F1
chr174577183245771868+intron-Distal4.209188.53428HepG2FAM120A
chr174577165145771740+intron-Distal,intron-Proximal3.967696.22491K562AGGF1
chr174577232145772339+intron-Distal4.3418511.49466HepG2CSTF2T
chr174577250245772554+intron-Distal3.234283.37567HepG2HNRNPK
chr174577162645771669+intron-Distal,intron-Proximal5.3108810.80898HepG2PRPF4
chr174578421745784385+intron-Distal3.990013.37631K562HNRNPL
chr174577225345772306+intron-Distal5.8511627.65224HepG2CSTF2T
chr174577189945771940+intron-Distal4.533916.06839HepG2PRPF4
chr174577168845771753+intron-Distal4.623444.01285K562GEMIN5
chr174577160545771697+intron-Distal,intron-Proximal5.445708.08420HepG2FASTKD2
chr174577226645772317+intron-Distal4.581575.18111K562CSTF2T
chr174577212345772193+intron-Distal,intron-Proximal4.147547.20767HepG2GTF2F1
chr174577164545771695+intron-Distal,intron-Proximal4.1566022.63513HepG2FAM120A
chr174577214145772206+intron-Distal4.5415411.86251HepG2PRPF4
chr174577169545771771+intron-Distal3.1784811.81477HepG2FAM120A
chr174577161845771682+intron-Distal,intron-Proximal7.4735838.92031HepG2CSTF2T
chr174577230645772321+intron-Distal6.4116322.52766HepG2CSTF2T
chr174577163045771678+intron-Distal,intron-Proximal3.259863.37274K562AKAP8L
chr174577214145772202+intron-Distal4.656644.84484K562AKAP8L
chr174577227045772302+intron-Distal4.657944.14518HepG2GTF2F1
chr174577233945772475+intron-Distal4.6388428.51904HepG2CSTF2T
chr174577162045771712+intron-Distal,intron-Proximal5.215777.57617HepG2GTF2F1
chr174577209545772141+intron-Distal,intron-Proximal4.732965.83275HepG2PRPF4
chr174577211645772229+intron-Distal,intron-Proximal5.140869.09259HepG2DROSHA
chr174577213145772199+intron-Distal4.118565.64872HepG2NKRF
chr174577227045772312+intron-Distal4.221408.27535HepG2FAM120A
chr174577174845771788+intron-Distal6.3065617.44070HepG2CSTF2T
chr174577225845772302+intron-Distal4.244004.14056K562EWSR1
chr174577162445771668+intron-Distal,intron-Proximal3.922673.30336K562EWSR1
chr174577212645772202+intron-Distal,intron-Proximal5.7572539.61183HepG2CSTF2T
chr174577161945771680+intron-Distal,intron-Proximal4.574154.95161K562GTF2F1
chr174577258845772606+intron-Distal4.543177.96122HepG2CSTF2T
chr174577213645772187+intron-Distal4.400244.98766K562EWSR1
chr174577251545772545+intron-Distal3.452777.30591HepG2CSTF2T
chr174577168245771748+intron-Distal6.9979929.69329HepG2CSTF2T
chr174577212445772196+intron-Distal,intron-Proximal4.906454.06667K562GTF2F1
chr174577233445772377+intron-Distal3.827877.46919HepG2FAM120A
chr174577226445772359+intron-Distal3.768855.88888HepG2AGGF1
chr174577162145771675+intron-Distal,intron-Proximal4.436825.40707K562CSTF2T
chr174577169745771752+intron-Distal3.508476.02860HepG2FASTKD2
chr174577188445771969+intron-Distal5.1441528.95844HepG2CSTF2T
chr174577209645772156+intron-Distal,intron-Proximal4.002333.71567HepG2RBFOX2
chr174577875345778809+intron-Distal3.151453.76460HepG2HNRNPL
chr174578775545787838+intron-Distal,intron-Proximal3.212083.27165HepG2RBFOX2
chr174577225645772314+intron-Distal4.235067.72829HepG2FASTKD2
chr174577214345772202+intron-Distal5.311515.70239K562DROSHA
chr174577187745771945+intron-Distal3.836805.82900HepG2GTF2F1
chr174577158045771618+intron-Proximal5.6249124.36373HepG2CSTF2T
chr174577157345771626+intron-Proximal4.079718.17769HepG2PRPF4
chr174577159245771621+intron-Proximal5.4744310.80838HepG2FAM120A
chr174577162145771645+intron-Proximal5.1568627.57050HepG2FAM120A
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TBKBP1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TBKBP1 is not available on ENCORE database.

  • 89 RBPs can affect the levels of TBKBP1.  








The Knockdown/knockout RNA-Seq assay for TBKBP1 is not available on ENCORE database.





89 RBPs can affect the gene expression of TBKBP1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TBKBP1ENSG00000198933.5626.62350476.361800.395403.620902.94210HepG2ACO1
TBKBP1ENSG00000198933.5836.88680600.174700.479602.894402.19440HepG2AUH
TBKBP1ENSG00000198933.5209.00370327.04650-0.646003.024702.22020HepG2CALR
TBKBP1ENSG00000198933.5192.13980477.34210-1.312905.222504.17750HepG2CIRBP
TBKBP1ENSG00000198933.5165.51300288.30470-0.800603.661102.01170HepG2CSTF2T
TBKBP1ENSG00000198933.5596.04510405.650800.555106.503305.43490HepG2DAZAP1
TBKBP1ENSG00000198933.5160.10090310.04540-0.953506.836805.81970HepG2DDX21
TBKBP1ENSG00000198933.5182.68770303.75690-0.733503.848302.75930HepG2DDX24
TBKBP1ENSG00000198933.5579.86990826.55280-0.511404.267302.67750HepG2DDX47
TBKBP1ENSG00000198933.5315.43060427.08510-0.437202.306701.38470HepG2DDX5
TBKBP1ENSG00000198933.5795.10270499.884000.669402.923502.29030HepG2DDX6
TBKBP1ENSG00000198933.5235.27840455.73530-0.9538011.068109.90030HepG2DKC1
TBKBP1ENSG00000198933.5377.70150202.588900.898606.762105.70080HepG2DNAJC21
TBKBP1ENSG00000198933.5263.37700200.844100.391002.084201.50300HepG2DNAJC2
TBKBP1ENSG00000198933.5313.98700530.62920-0.757002.724202.08970HepG2EIF4A3
TBKBP1ENSG00000198933.5618.93970400.219100.628907.348506.10140HepG2EIF4G1
TBKBP1ENSG00000198933.5545.11620319.778100.769405.671704.77740HepG2GPKOW
TBKBP1ENSG00000198933.5599.58740381.928400.650603.748502.45080HepG2GRSF1
TBKBP1ENSG00000198933.5532.83600349.148600.609803.435501.90020HepG2HNRNPA0
TBKBP1ENSG00000198933.5447.08690270.045600.727307.649806.53700HepG2HNRNPF
TBKBP1ENSG00000198933.5554.90010369.509900.586506.766905.75730HepG2HNRNPL
TBKBP1ENSG00000198933.5356.68180226.011400.658105.442304.61410HepG2HNRNPU
TBKBP1ENSG00000198933.5928.96960536.110400.793003.534802.59480HepG2LARP4
TBKBP1ENSG00000198933.5301.69370535.97280-0.829102.997902.31610HepG2MAGOH
TBKBP1ENSG00000198933.5524.54440402.243700.382902.675901.92570HepG2NOL12
TBKBP1ENSG00000198933.5379.31750211.968000.839504.310402.52530HepG2NOLC1
TBKBP1ENSG00000198933.5666.84830270.603701.3011017.1437015.47070HepG2NSUN2
TBKBP1ENSG00000198933.5291.71190490.94610-0.751002.771702.04960HepG2PABPC4
TBKBP1ENSG00000198933.5317.24630201.581600.654104.131203.24740HepG2PPIL4
TBKBP1ENSG00000198933.5568.03130375.791300.595906.284905.17110HepG2PRPF4
TBKBP1ENSG00000198933.5148.63670211.63010-0.509802.153701.43740HepG2PRPF8
TBKBP1ENSG00000198933.5491.45690383.983200.355902.015901.49560HepG2PUF60
TBKBP1ENSG00000198933.5862.99370407.320101.0831018.8705017.21350HepG2PUM2
TBKBP1ENSG00000198933.5278.27820485.19760-0.802009.787508.74890HepG2PUS1
TBKBP1ENSG00000198933.5594.57910323.311200.878807.731306.06230HepG2RBM27
TBKBP1ENSG00000198933.5294.14310201.264500.547303.516202.80600HepG2SAFB2
TBKBP1ENSG00000198933.5267.73600643.89110-1.2660012.6428011.13990HepG2SF3A3
TBKBP1ENSG00000198933.5430.44850192.648101.159802.912301.41800HepG2SFPQ
TBKBP1ENSG00000198933.5472.89370368.195200.360902.650501.96170HepG2SLBP
TBKBP1ENSG00000198933.5486.29330336.087600.532902.249401.54790HepG2SNRNP70
TBKBP1ENSG00000198933.5178.39250562.92000-1.6579030.7341029.53280HepG2SRSF1
TBKBP1ENSG00000198933.5525.64420379.136300.471304.109503.37510HepG2SRSF5
TBKBP1ENSG00000198933.5379.19340265.303600.515203.941803.13280HepG2SRSF7
TBKBP1ENSG00000198933.5233.20420564.77620-1.2761022.7614021.60230HepG2SSB
TBKBP1ENSG00000198933.5517.56330360.713500.520802.518301.47590HepG2STIP1
TBKBP1ENSG00000198933.5649.16870431.174800.590207.102906.18640HepG2SUCLG1
TBKBP1ENSG00000198933.5447.50890273.249100.711603.381902.64270HepG2SUPV3L1
TBKBP1ENSG00000198933.5465.26690297.487400.645104.504103.60780HepG2TARDBP
TBKBP1ENSG00000198933.5343.38120219.557300.645104.468403.86460HepG2TIAL1
TBKBP1ENSG00000198933.5340.12540221.579100.618104.874304.16850HepG2TRIM56
TBKBP1ENSG00000198933.5576.83910375.147400.620605.434904.16120HepG2TUFM
TBKBP1ENSG00000198933.5597.59880161.387101.8886029.0010026.67460HepG2UCHL5
TBKBP1ENSG00000198933.5386.89960250.098600.629402.193001.30500HepG2UPF2
TBKBP1ENSG00000198933.5279.33190551.30980-0.9809013.1135011.95290HepG2UTP3
TBKBP1ENSG00000198933.5211.41180370.84760-0.810807.864006.82740HepG2ZC3H8
TBKBP1ENSG00000198933.5215.22040628.02690-1.5450036.7194035.31640HepG2ZNF622
TBKBP1ENSG00000198933.5792.91060551.170700.524606.448905.63510K562AGGF1
TBKBP1ENSG00000198933.5799.23530605.697900.399903.217802.13810K562AKAP8
TBKBP1ENSG00000198933.5776.41050573.529100.436903.001502.32010K562AKAP8L
TBKBP1ENSG00000198933.5434.13780598.82560-0.464002.693102.11140K562AQR
TBKBP1ENSG00000198933.5771.40560601.790800.358103.256802.26020K562ATP5C1
TBKBP1ENSG00000198933.5160.81490306.20400-0.929106.072804.76840K562BOP1
TBKBP1ENSG00000198933.5420.71960279.208800.591402.909301.82510K562CCAR1
TBKBP1ENSG00000198933.5310.63790193.998400.679104.092302.77630K562CSTF2
TBKBP1ENSG00000198933.5821.19360561.066400.549506.784505.82900K562DDX47
TBKBP1ENSG00000198933.5818.75050617.089500.407804.261303.14070K562DKC1
TBKBP1ENSG00000198933.5374.82320226.169300.728704.169703.02880K562EFTUD2
TBKBP1ENSG00000198933.5482.15130283.999100.763504.016202.78060K562EIF3A
TBKBP1ENSG00000198933.5246.89530136.745200.852305.797304.65960K562EIF3G
TBKBP1ENSG00000198933.5547.75890411.017100.414202.840801.55750K562EXOSC5
TBKBP1ENSG00000198933.5224.28540339.23320-0.596904.034103.32410K562FXR1
TBKBP1ENSG00000198933.531.62700117.45760-1.892908.742907.33960K562G3BP2
TBKBP1ENSG00000198933.5702.67910472.202600.573404.556903.58920K562GRSF1
TBKBP1ENSG00000198933.5389.33580286.017100.444802.296801.74590K562HNRNPC
TBKBP1ENSG00000198933.5693.31860505.806600.454803.926102.85660K562HNRNPU
TBKBP1ENSG00000198933.5323.79560197.246300.715003.751002.48730K562IGF2BP2
TBKBP1ENSG00000198933.5344.45460207.177600.733305.460104.26620K562MAGOH
TBKBP1ENSG00000198933.5367.47680206.739000.829707.126205.55200K562MATR3
TBKBP1ENSG00000198933.5730.60080570.847900.355903.559902.72360K562NSUN2
TBKBP1ENSG00000198933.5359.79050522.80980-0.539103.234702.33540K562PCBP3
TBKBP1ENSG00000198933.5276.43400400.99000-0.536603.677902.74740K562POLR2G
TBKBP1ENSG00000198933.5413.98070256.465900.690704.342103.17050K562PSIP1
TBKBP1ENSG00000198933.5371.41560201.295000.883608.134107.03870K562PTBP1
TBKBP1ENSG00000198933.5462.79230730.70840-0.658907.709005.85430K562PUM1
TBKBP1ENSG00000198933.5754.99760554.182300.446004.324903.59990K562RBM15
TBKBP1ENSG00000198933.5347.37750192.952100.848206.683305.30860K562RBM22
TBKBP1ENSG00000198933.5282.89430188.141800.588302.979001.52030K562RBM34
TBKBP1ENSG00000198933.5505.39690224.094901.1732010.201008.61290K562RPS19
TBKBP1ENSG00000198933.5340.49700219.640600.632403.039101.98480K562RPS3
TBKBP1ENSG00000198933.5198.43540122.027200.701403.548102.57550K562SF3B4
TBKBP1ENSG00000198933.5324.16890221.906000.546702.769101.74390K562SRFBP1
TBKBP1ENSG00000198933.5327.04270197.349800.728604.842003.91110K562SRSF1
TBKBP1ENSG00000198933.5328.96900212.022200.633603.508502.30310K562SRSF4
TBKBP1ENSG00000198933.5302.98920186.415500.700604.413503.03570K562SRSF5
TBKBP1ENSG00000198933.5306.10220402.23510-0.394002.269301.52480K562SYNCRIP
TBKBP1ENSG00000198933.5354.70140199.701700.828706.111505.02860K562TARDBP
TBKBP1ENSG00000198933.5354.08030192.642500.878107.227305.80480K562TIA1
TBKBP1ENSG00000198933.5392.25210246.664700.669104.036902.89120K562TIAL1
TBKBP1ENSG00000198933.5350.72030189.108600.891003.060701.90340K562TRA2A
TBKBP1ENSG00000198933.5384.41640262.165500.552102.391701.52170K562TRIM56
TBKBP1ENSG00000198933.5339.62110225.443100.591102.204001.30230K562UCHL5
TBKBP1ENSG00000198933.5288.00320537.89930-0.901307.245605.35240K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TBKBP1 is not available on ENCORE database.





1 RBPs can affect the splicing of TBKBP1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETBKBP1ENSG00000198933.5chr17+457855154578560645777001457770634578575945785878-0.427000.000070.01987excludedK562LARP4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TBKBP1 is not avaliable on ENCORE database.