SYNGAP1

General Information

Gene Name       : SYNGAP1
Gene ID             : ENSG00000197283.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SYNGAP1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SYNGAP1ENSG00000197283.161.953.892.92ENCSR000AEF
HepG2SYNGAP1ENSG00000197283.164.362.763.56ENCSR985KAT
K562SYNGAP1ENSG00000197283.1610.059.589.82ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SYNGAP1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SYNGAP1 RNA is bound by 24 proteins.  







eCLIP assay for SYNGAP1 is not avaliable on ENCORE database.





24 proteins are bound to SYNGAP1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63342131733421366+3'-UTR3.342345.08563K562HNRNPK
chr63342132633421413+3'-UTR4.010554.07750HepG2HNRNPK
chr63342132233421405+3'-UTR4.354817.31085HepG2PCBP2
chr63342137033421429+3'-UTR4.1214411.58826K562PUM2
chr63342122133421240+3'-UTR5.436477.24744K562PUM2
chr63341977933419819+3'-UTR4.378833.98353K562RBM15
chr63342106933421112+3'-UTR4.253557.04643K562PUM2
chr63341988533420047+3'-UTR4.164037.29082K562HNRNPK
chr63342080933420845+3'-UTR3.990697.47094K562PUM2
chr63342136633421416+3'-UTR3.472477.03533K562HNRNPK
chr63342114833421221+3'-UTR6.0747668.92680K562PUM2
chr63342132533421417+3'-UTR3.573744.34517K562DDX55
chr63342109833421142+3'-UTR3.831705.76537HepG2PCBP2
chr63340583633405952+CDS5.6349110.65697K562UCHL5
chr63341090733410949+CDS3.539794.46749K562RBM15
chr63340557433405624+CDS4.231249.04978K562RBM15
chr63340845633408537+CDS,intron-Proximal4.417584.86763HepG2PCBP2
chr63341440633414509+CDS4.818786.44794K562UCHL5
chr63340570433405762+CDS4.849626.89039K562RBM15
chr63341561633415662+CDS,intron-Proximal3.351884.74755K562ZNF622
chr63340655333406667+CDS3.052374.30558K562UCHL5
chr63340054033400579+CDS3.483403.90826K562ZNF622
chr63340583133405923+CDS4.016529.70967K562RBM15
chr63340581733405903+CDS4.282053.71567HepG2RBFOX2
chr63341216633412294+CDS,intron-Proximal3.031413.46866HepG2U2AF2
chr63340584433405897+CDS4.127123.49905HepG2PPIG
chr63340583233405892+CDS4.768699.73538K562DDX24
chr63340853433408579+CDS3.364373.04831K562RBM15
chr63341223733412330+CDS4.052065.42720K562UCHL5
chr63340564433405737+CDS3.930533.79347HepG2GRWD1
chr63340655133406689+CDS,intron-Proximal3.294566.79558K562ZNF622
chr63340655433406661+CDS4.315855.49297K562GRWD1
chr63340582833405894+CDS4.335743.70701HepG2PRPF4
chr63340655033406666+CDS,intron-Proximal3.124043.39306HepG2GRWD1
chr63340853733408577+CDS4.100484.12139K562DDX24
chr63340584133405892+CDS4.690924.90367K562ZNF622
chr63341934233419573+CDS,intron-Distal,intron-Proximal3.064728.15774K562PRPF8
chr63341221333412354+CDS,intron-Proximal3.031183.17744HepG2GRWD1
chr63341096933411017+CDS5.093297.23707K562RBM15
chr63340582433405907+CDS4.9120611.30843K562GTF2F1
chr63340583333405903+CDS3.699894.57350K562RBFOX2
chr63340554833405644+CDS3.059073.63043HepG2GRWD1
chr63340054233400583+CDS4.296995.05122K562DDX24
chr63340620133406247+CDS4.175113.28989K562RBM15
chr63340563233405732+CDS5.5031610.53537K562ZNF622
chr63340599533406043+CDS4.338664.96452K562YBX3
chr63341224333412287+CDS4.239255.05122K562DDX24
chr63340655233406633+CDS3.813733.59112HepG2PPIG
chr63341591333416002+intron-Distal3.693123.06617K562HNRNPK
chr63341941333419494+intron-Distal,intron-Proximal5.8950610.13695K562EFTUD2
chr63339600533396053+intron-Distal4.313343.77360K562GTF2F1
chr63338874133388822+intron-Distal3.310633.07801K562UPF1
chr63341935533419472+intron-Distal,intron-Proximal3.809485.05356HepG2PRPF8
chr63341198233412029+intron-Distal4.127143.85435K562PRPF8
chr63340836733408444+intron-Distal,intron-Proximal3.248053.85034K562ILF3
chr63340834333408425+intron-Distal,intron-Proximal5.7919313.20639HepG2PCBP2
chr63341174233411838+intron-Distal,intron-Proximal4.681374.48002K562AQR
chr63341046733410535+intron-Distal4.220344.47904K562HNRNPK
chr63339750533397554+intron-Distal3.762203.08314K562TARDBP
chr63340185533401986+intron-Distal4.292113.09122HepG2PTBP1
chr63341039033410460+intron-Distal3.769123.06617K562HNRNPK
chr63339740933397505+intron-Distal4.491924.66266K562TARDBP
chr63338872033388819+intron-Distal3.469844.05280K562CSTF2T
chr63341868733418762+intron-Distal4.533315.53033K562HNRNPK
chr63339613933396202+intron-Distal4.089254.04290K562CSTF2T
chr63339552933395620+intron-Distal4.069913.59342K562CSTF2T
chr63341216733412217+intron-Proximal3.627143.88924K562PRPF8
chr63341057433410659+intron-Proximal4.519436.59856K562SF3B4
chr63340953633409615+intron-Proximal4.874885.69951K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SYNGAP1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SYNGAP1 is not available on ENCORE database.

  • 105 RBPs can affect the levels of SYNGAP1.  








The Knockdown/knockout RNA-Seq assay for SYNGAP1 is not available on ENCORE database.





105 RBPs can affect the gene expression of SYNGAP1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SYNGAP1ENSG00000197283.8366.30660217.203600.753907.011906.13370HepG2ACO1
SYNGAP1ENSG00000197283.8448.67100172.518001.3788012.0264010.99450HepG2AKAP1
SYNGAP1ENSG00000197283.8342.84170196.369400.803904.921703.54720HepG2AKAP8
SYNGAP1ENSG00000197283.8392.41130218.220000.846505.786704.71450HepG2AKAP8L
SYNGAP1ENSG00000197283.8253.82860142.740700.830404.425503.44260HepG2ASCC1
SYNGAP1ENSG00000197283.8527.58970399.021400.402903.276702.53970HepG2AUH
SYNGAP1ENSG00000197283.8607.85490438.964500.469503.221302.58170HepG2BOP1
SYNGAP1ENSG00000197283.8381.99710276.396200.466702.534201.35710HepG2BUD13
SYNGAP1ENSG00000197283.81500.82080510.158101.5566024.4022021.75490HepG2CCAR1
SYNGAP1ENSG00000197283.8280.43950173.957400.688902.774202.00860HepG2CNOT7
SYNGAP1ENSG00000197283.8300.78910402.99560-0.422002.087301.48030HepG2CPSF6
SYNGAP1ENSG00000197283.8111.05380175.63960-0.661402.698801.63460HepG2CSTF2
SYNGAP1ENSG00000197283.8397.32590291.996000.444303.061002.39120HepG2CELF1
SYNGAP1ENSG00000197283.8282.82280165.251900.775104.094803.34610HepG2DDX3X
SYNGAP1ENSG00000197283.8306.47460193.026800.666904.090902.47130HepG2DDX52
SYNGAP1ENSG00000197283.8279.28230457.63040-0.712503.231602.17740HepG2DDX59
SYNGAP1ENSG00000197283.8181.97480270.52830-0.572002.767101.75530HepG2DDX5
SYNGAP1ENSG00000197283.8310.87770141.972001.130607.559306.58320HepG2DDX6
SYNGAP1ENSG00000197283.8340.96120245.352500.474703.376702.66940HepG2DNAJC2
SYNGAP1ENSG00000197283.8198.42250136.464000.540001.813501.32120HepG2EIF2S1
SYNGAP1ENSG00000197283.8328.12970186.989000.811204.966803.78170HepG2EIF3D
SYNGAP1ENSG00000197283.8302.03440146.841301.040405.654104.69410HepG2EIF4B
SYNGAP1ENSG00000197283.8569.32500458.107400.313502.381101.81560HepG2ETF1
SYNGAP1ENSG00000197283.8929.67780372.598801.3190015.6804014.09890HepG2FIP1L1
SYNGAP1ENSG00000197283.8383.51310248.876100.623703.066601.89100HepG2FUS
SYNGAP1ENSG00000197283.8341.88600152.176401.167709.091807.90260HepG2FXR1
SYNGAP1ENSG00000197283.8665.07720141.152802.2362038.3102035.96470HepG2G3BP1
SYNGAP1ENSG00000197283.8298.14890166.493600.840505.437004.17630HepG2GEMIN5
SYNGAP1ENSG00000197283.8496.87490248.318401.000609.089607.21400HepG2GNB2L1
SYNGAP1ENSG00000197283.8283.98500161.056400.818104.015602.67420HepG2GRSF1
SYNGAP1ENSG00000197283.8346.13530249.870200.470102.002801.44280HepG2HNRNPA1
SYNGAP1ENSG00000197283.8208.69270432.40490-1.0510013.1728011.76180HepG2HNRNPF
SYNGAP1ENSG00000197283.8300.87400142.960701.073407.421306.31900HepG2HNRNPK
SYNGAP1ENSG00000197283.8381.20840285.972300.414602.849602.16750HepG2HNRNPL
SYNGAP1ENSG00000197283.8295.67300435.96390-0.560203.208002.53630HepG2HNRNPLL
SYNGAP1ENSG00000197283.8499.62850276.108900.855509.261908.20100HepG2HNRNPU
SYNGAP1ENSG00000197283.8388.15480213.764400.860505.273803.59990HepG2HSPD1
SYNGAP1ENSG00000197283.8213.35750425.79450-0.9969010.483709.16110HepG2IGF2BP1
SYNGAP1ENSG00000197283.8269.92870143.474100.911705.386604.47230HepG2IGF2BP2
SYNGAP1ENSG00000197283.8265.39880144.319100.878804.242502.97690HepG2KHSRP
SYNGAP1ENSG00000197283.8413.53480213.620100.952903.097301.77230HepG2KRR1
SYNGAP1ENSG00000197283.8495.36100153.077601.6941018.8728017.34200HepG2MATR3
SYNGAP1ENSG00000197283.8380.03110195.710500.957303.221902.08680HepG2METAP2
SYNGAP1ENSG00000197283.81002.90400156.680102.6782031.8164029.85380HepG2NCBP2
SYNGAP1ENSG00000197283.8451.90670311.307800.537604.218303.27690HepG2NOL12
SYNGAP1ENSG00000197283.8181.22470386.56070-1.092908.536907.27440HepG2NSUN2
SYNGAP1ENSG00000197283.8223.53370139.518700.679903.031302.27740HepG2PABPC4
SYNGAP1ENSG00000197283.8378.47240273.284100.469703.170102.26950HepG2PARN
SYNGAP1ENSG00000197283.8272.09260145.840900.899606.869105.98170HepG2PCBP1
SYNGAP1ENSG00000197283.8121.40200215.63310-0.828804.334803.34770HepG2PRPF8
SYNGAP1ENSG00000197283.8333.86280148.395201.169708.369307.52390HepG2PTBP1
SYNGAP1ENSG00000197283.8436.23380315.473900.467503.992203.30780HepG2PUM1
SYNGAP1ENSG00000197283.8616.36570315.238800.9672012.6706011.29720HepG2PUM2
SYNGAP1ENSG00000197283.8297.16050221.235200.425602.414701.82910HepG2PUS1
SYNGAP1ENSG00000197283.8234.60100160.722800.545502.416701.82660HepG2QKI
SYNGAP1ENSG00000197283.861.79730227.30020-1.8790010.575209.26340HepG2RAVER1
SYNGAP1ENSG00000197283.8501.64820386.182500.377302.293801.50500HepG2RBM15
SYNGAP1ENSG00000197283.8530.72370382.897700.470903.647603.07460HepG2RBM22
SYNGAP1ENSG00000197283.8361.83640165.152401.1314011.0482010.10290HepG2NELFE
SYNGAP1ENSG00000197283.8260.94640153.812000.762504.717303.94190HepG2RECQL
SYNGAP1ENSG00000197283.8182.54180465.81960-1.3515016.0597014.67760HepG2RPLP0
SYNGAP1ENSG00000197283.8395.28400181.936001.1194010.984109.85760HepG2RPS19
SYNGAP1ENSG00000197283.8362.39440270.520000.421702.027401.33560HepG2RPS2
SYNGAP1ENSG00000197283.8289.59080140.349801.044902.663801.34680HepG2SF1
SYNGAP1ENSG00000197283.8249.94550345.52900-0.467202.085401.49880HepG2SF3A3
SYNGAP1ENSG00000197283.8146.10560431.52180-1.5624017.9494016.32110HepG2SF3B1
SYNGAP1ENSG00000197283.8216.28720154.504500.485201.964901.45260HepG2SF3B4
SYNGAP1ENSG00000197283.8445.59410136.033401.711706.054903.74870HepG2SFPQ
SYNGAP1ENSG00000197283.8410.10280286.724000.516204.169703.40860HepG2SMN1
SYNGAP1ENSG00000197283.8276.84320125.251401.144103.300601.83920HepG2SNRNP200
SYNGAP1ENSG00000197283.8240.61040432.47720-0.845909.182308.41590HepG2SRFBP1
SYNGAP1ENSG00000197283.8483.98260293.427900.721807.790606.81060HepG2SRSF5
SYNGAP1ENSG00000197283.8218.87900424.82670-0.9567011.212509.97430HepG2SRSF7
SYNGAP1ENSG00000197283.8191.15630375.50710-0.9741010.182709.31820HepG2SSB
SYNGAP1ENSG00000197283.8594.46290333.700700.8329011.9649010.82510HepG2SUCLG1
SYNGAP1ENSG00000197283.8182.03490251.51670-0.466402.491301.59680HepG2SUPT6H
SYNGAP1ENSG00000197283.8222.31700144.946200.617003.110502.52100HepG2TAF15
SYNGAP1ENSG00000197283.8425.16600209.249501.022704.488003.15310HepG2TBRG4
SYNGAP1ENSG00000197283.8413.80720270.692800.612205.581804.83270HepG2TRIM56
SYNGAP1ENSG00000197283.8571.23080145.935701.968608.589106.76440HepG2U2AF2
SYNGAP1ENSG00000197283.8511.98860306.429900.740508.829507.70080HepG2UPF1
SYNGAP1ENSG00000197283.8510.83480295.848300.787909.144308.15980HepG2UTP3
SYNGAP1ENSG00000197283.8250.62380337.01630-0.427302.761202.21460HepG2ZNF622
SYNGAP1ENSG00000197283.8882.452101132.31660-0.359702.537201.96980K562AQR
SYNGAP1ENSG00000197283.8915.80670688.119800.412304.137702.47590K562BCCIP
SYNGAP1ENSG00000197283.81581.36030812.496300.9606015.9653012.84630K562CCAR1
SYNGAP1ENSG00000197283.81440.164101099.513200.389303.899702.96970K562CPSF6
SYNGAP1ENSG00000197283.8491.01820650.61570-0.406002.321901.38340K562EIF3D
SYNGAP1ENSG00000197283.8559.16470718.98880-0.362703.024302.39520K562FXR1
SYNGAP1ENSG00000197283.8192.14190461.54320-1.2643010.482808.93680K562G3BP2
SYNGAP1ENSG00000197283.8815.01020579.710300.491404.149901.63580K562GRWD1
SYNGAP1ENSG00000197283.81060.55160667.087900.668808.228207.24810K562HNRNPC
SYNGAP1ENSG00000197283.8779.50780595.655300.388002.828301.67440K562HNRNPF
SYNGAP1ENSG00000197283.8532.33240847.89610-0.671603.999602.86600K562HNRNPM
SYNGAP1ENSG00000197283.81325.66770931.515200.509007.095405.66350K562HNRNPU
SYNGAP1ENSG00000197283.81112.668101397.78830-0.329102.519201.75620K562HSPD1
SYNGAP1ENSG00000197283.8942.12500628.225600.584504.286302.89000K562IGF2BP2
SYNGAP1ENSG00000197283.81026.07450645.824800.667803.412901.82770K562LARP7
SYNGAP1ENSG00000197283.81073.79850676.461900.666506.716704.24550K562LIN28B
SYNGAP1ENSG00000197283.8892.53980594.705400.585605.898703.57150K562LSM11
SYNGAP1ENSG00000197283.8887.87350658.274800.431603.052402.08070K562MATR3
SYNGAP1ENSG00000197283.81268.954701024.666400.308402.419801.60370K562METAP2
SYNGAP1ENSG00000197283.8849.704701170.22530-0.461802.721401.90870K562PPIG
SYNGAP1ENSG00000197283.8371.44790591.49020-0.671205.437304.38280K562PRPF8
SYNGAP1ENSG00000197283.8973.68080598.098900.703007.962806.26780K562PSIP1
SYNGAP1ENSG00000197283.81504.729201854.71510-0.301702.935101.83360K562PUM1
SYNGAP1ENSG00000197283.8308.95970437.52810-0.502003.304501.83860K562RBM25
SYNGAP1ENSG00000197283.8818.56600599.074900.450303.219101.68560K562RBM34
SYNGAP1ENSG00000197283.8989.65960646.545800.614104.366902.96010K562NELFE
SYNGAP1ENSG00000197283.8411.22690604.63000-0.556103.189201.76130K562RRP9
SYNGAP1ENSG00000197283.81619.893901332.982100.281102.907802.07440K562SF3A3
SYNGAP1ENSG00000197283.81985.98730886.492301.163606.929204.50430K562SFPQ
SYNGAP1ENSG00000197283.8958.09220517.235100.8892011.991309.45560K562SRFBP1
SYNGAP1ENSG00000197283.81715.016401365.666400.328504.913603.71070K562SRPK2
SYNGAP1ENSG00000197283.81027.22370718.711800.515204.989303.50540K562SRSF4
SYNGAP1ENSG00000197283.8740.94270959.85490-0.373502.216101.48030K562SYNCRIP
SYNGAP1ENSG00000197283.81115.05630635.882300.810207.396206.17870K562TARDBP
SYNGAP1ENSG00000197283.8790.67880613.414900.366102.168001.45080K562TIA1
SYNGAP1ENSG00000197283.8975.66500575.280000.762007.974706.31520K562TIAL1
SYNGAP1ENSG00000197283.81134.15500611.078300.8921012.8281010.46680K562TRIM56
SYNGAP1ENSG00000197283.8321.74300461.86560-0.521603.936002.97970K562U2AF2
SYNGAP1ENSG00000197283.82669.007601965.964100.441005.391803.46810K562UBE2L3
SYNGAP1ENSG00000197283.81693.230701341.718100.335603.055301.69140K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SYNGAP1 is not available on ENCORE database.





4 RBPs can affect the splicing of SYNGAP1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESYNGAP1ENSG00000197283.8chr6+3341022933410271334093573340953633410665334117370.150000.003690.08358includedK562AKAP8L
SESYNGAP1ENSG00000197283.8chr6+334102293341027133409357334095363341066533411737-0.098000.001340.07876excludedK562HNRNPL
SESYNGAP1ENSG00000197283.8chr6+3341022933410271334093573340953633410665334117370.220000.000150.00628includedK562AGGF1
SESYNGAP1ENSG00000197283.8chr6+3341022933410271334093573340953633410665334117370.808000.000000.00000includedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SYNGAP1 is not avaliable on ENCORE database.