STX4

General Information

Gene Name       : STX4
Gene ID             : ENSG00000103496.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: STX4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878STX4ENSG00000103496.1410.2214.9412.58ENCSR000AEF
HepG2STX4ENSG00000103496.1437.3825.0631.22ENCSR985KAT
K562STX4ENSG00000103496.1426.5720.6123.59ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for STX4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • STX4 RNA is bound by 24 proteins.  







eCLIP assay for STX4 is not avaliable on ENCORE database.





24 proteins are bound to STX4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr163104944531049509+3'-UTR,CDS3.364645.74981HepG2GRWD1
chr163104930231049356+3'-UTR,CDS,intron-Proximal4.229434.96634HepG2PPIG
chr163104994331050011+3'-UTR,CDS,intron-Proximal5.3332416.15035HepG2PRPF8
chr163104943431049496+3'-UTR,CDS,intron-Proximal3.673703.01533HepG2SRSF1
chr163104943331049510+3'-UTR,CDS,intron-Proximal4.2993312.68282HepG2PPIG
chr163104948431049511+3'-UTR,CDS4.554104.78529HepG2BCLAF1
chr163104994731050003+3'-UTR,CDS,intron-Proximal3.495623.88924K562PRPF8
chr163104930031049356+3'-UTR,CDS,intron-Proximal4.173293.80990HepG2SRSF1
chr163104943731049470+3'-UTR,CDS4.469144.70478HepG2BCLAF1
chr163104927531049355+3'-UTR,CDS3.982174.17155HepG2BCLAF1
chr163104924631049262+3'-UTR,CDS,intron-Proximal4.439934.67689HepG2PPIG
chr163104983231049844+3'-UTR,CDS3.393963.93645HepG2PPIG
chr163105105531051140+3'-UTR,CDS,intron-Proximal3.827008.94272HepG2GRWD1
chr163104944131049511+3'-UTR,CDS3.713114.49887K562ZNF622
chr163104500031045077+5'-UTR,intron-Distal4.123646.85082HepG2FAM120A
chr163104498631045135+5'-UTR,CDS,intron-Distal4.6341119.83756K562GTF2F1
chr163104501231045084+5'-UTR,intron-Distal4.462939.69852HepG2GTF2F1
chr163104497231045066+5'-UTR,intron-Distal3.222093.58695HepG2GRSF1
chr163104499631045067+5'-UTR,intron-Distal4.700274.78731HepG2NCBP2
chr163104502431045146+5'-UTR,CDS,intron-Distal3.2084511.71611HepG2PPIG
chr163104577931045856+5'-UTR,CDS,intron-Proximal3.265484.85880HepG2PPIG
chr163104501231045138+5'-UTR,CDS,intron-Distal3.452846.27275HepG2DDX3X
chr163104487531044996+5'-UTR,intron-Distal,intron-Proximal3.693586.14786HepG2NCBP2
chr163104506731045157+5'-UTR,CDS,intron-Distal,intron-Proximal3.052763.65693HepG2NCBP2
chr163104555331045610+5'-UTR,CDS3.568364.49887K562ZNF622
chr163104500531045133+5'-UTR,CDS,intron-Distal4.022447.30092HepG2PCBP2
chr163104567731045801+5'-UTR,CDS,intron-Proximal4.173503.90085K562MTPAP
chr163104488131044987+5'-UTR,intron-Distal,intron-Proximal4.3415810.36383HepG2PRPF4
chr163104501131045139+5'-UTR,CDS,intron-Distal3.167907.47782K562CSTF2T
chr163104576631045851+5'-UTR,CDS,intron-Proximal3.957767.94477HepG2GRWD1
chr163104508431045159+5'-UTR,CDS,intron-Distal,intron-Proximal3.867466.63019HepG2GTF2F1
chr163104500631045071+5'-UTR,intron-Distal4.4692115.89253HepG2PRPF4
chr163104506031045128+5'-UTR,CDS,intron-Distal4.0964310.40043K562DDX6
chr163104633131046361+5'-UTR,CDS4.590125.56813HepG2PPIG
chr163104501131045133+5'-UTR,CDS,intron-Distal3.521204.99980K562XRCC6
chr163104555531045659+5'-UTR,CDS,intron-Proximal3.982156.69386HepG2GRWD1
chr163104565631045829+5'-UTR,CDS,intron-Proximal3.138906.10449K562RBFOX2
chr163104507131045156+5'-UTR,CDS,intron-Distal4.3197616.59421HepG2PRPF4
chr163104491831045012+5'-UTR,intron-Distal,intron-Proximal6.0745711.20892HepG2DDX3X
chr163104491931044987+5'-UTR,intron-Distal,intron-Proximal3.559624.40383K562UCHL5
chr163104510031045133+5'-UTR,CDS,intron-Distal3.668133.14999HepG2GRWD1
chr163104502631045143+5'-UTR,CDS,intron-Distal4.739257.50842K562DDX24
chr163104500931045090+5'-UTR,intron-Distal3.689236.77949K562FASTKD2
chr163104500431045144+5'-UTR,CDS,intron-Distal3.007754.68798K562FUS
chr163104504031045157+5'-UTR,CDS,intron-Distal,intron-Proximal4.475516.47963K562DDX51
chr163104534031045417+CDS4.505114.53461K562SRSF1
chr163105086231050969+CDS3.8641610.05825HepG2GRWD1
chr163104535131045404+CDS3.846563.60441HepG2GRWD1
chr163105089631050977+CDS,intron-Proximal3.326826.02430HepG2PPIG
chr163104533231045431+CDS,intron-Proximal3.769644.96025HepG2SRSF1
chr163104535631045434+CDS3.792208.10600HepG2PPIG
chr163105104831051103+CDS3.248653.07653K562ZNF622
chr163105019831050391+intron-Distal4.439564.55788HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for STX4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for STX4 is not available on ENCORE database.

  • 66 RBPs can affect the levels of STX4.  








The Knockdown/knockout RNA-Seq assay for STX4 is not available on ENCORE database.





66 RBPs can affect the gene expression of STX4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
STX4ENSG00000103496.101038.95550760.440900.450103.103502.10360HepG2ABCF1
STX4ENSG00000103496.10952.88900647.970300.556303.754803.14830HepG2AKAP1
STX4ENSG00000103496.10814.60470618.564700.397104.045603.13120HepG2AKAP8L
STX4ENSG00000103496.10725.44900460.977500.654104.625403.41390HepG2BCCIP
STX4ENSG00000103496.10722.39420532.442800.440103.150602.51630HepG2BOP1
STX4ENSG00000103496.10691.27080509.345300.440502.713901.94880HepG2CIRBP
STX4ENSG00000103496.10685.11800569.418600.266802.238601.48290HepG2DDX19B
STX4ENSG00000103496.10676.62940480.563400.493503.804303.02160HepG2DDX21
STX4ENSG00000103496.10623.26390424.087800.555403.122001.75770HepG2DDX27
STX4ENSG00000103496.10931.67190620.619100.586004.212603.45360HepG2DDX3X
STX4ENSG00000103496.10881.90710453.231200.960309.595508.25710HepG2DDX55
STX4ENSG00000103496.10776.05280533.330500.541003.524002.83450HepG2DDX6
STX4ENSG00000103496.10856.18390512.499200.740306.937706.02790HepG2EIF2S1
STX4ENSG00000103496.10780.50970551.534900.500902.606001.93650HepG2EIF4B
STX4ENSG00000103496.101445.808401035.714900.481107.244506.34890HepG2ETF1
STX4ENSG00000103496.10661.44570470.101800.492503.609502.71820HepG2FUBP3
STX4ENSG00000103496.10829.32250571.644800.536703.995403.17360HepG2FXR1
STX4ENSG00000103496.10718.03720530.127100.437602.584501.94130HepG2G3BP1
STX4ENSG00000103496.10843.44890554.118800.606002.957702.29820HepG2GPKOW
STX4ENSG00000103496.10530.84010376.100600.497103.269102.57430HepG2HNRNPA1
STX4ENSG00000103496.10888.78110729.928100.284003.221402.49840HepG2HNRNPL
STX4ENSG00000103496.10744.71870538.806600.466803.058802.35310HepG2IGF2BP2
STX4ENSG00000103496.10623.81610424.508600.555207.078605.96280HepG2ILF2
STX4ENSG00000103496.101086.34320824.796200.397302.135201.41300HepG2LARP4
STX4ENSG00000103496.10956.24390571.845800.741707.178706.13760HepG2MAGOH
STX4ENSG00000103496.10811.22390621.462300.384302.791001.97980HepG2MSI2
STX4ENSG00000103496.10720.95380416.156700.792704.310302.92720HepG2NONO
STX4ENSG00000103496.10613.05300391.553700.646703.147902.19730HepG2PABPC1
STX4ENSG00000103496.10779.78410523.918200.573604.334103.44310HepG2PABPC4
STX4ENSG00000103496.10904.87240543.518500.7353010.324609.39880HepG2PTBP1
STX4ENSG00000103496.10925.28650627.125200.561008.515807.53600HepG2PUS1
STX4ENSG00000103496.101036.47150865.655400.259701.987201.52890HepG2RBM22
STX4ENSG00000103496.10702.25220534.157100.394602.677702.01260HepG2RBM25
STX4ENSG00000103496.10594.17330420.438700.498902.289701.32670HepG2RCC2
STX4ENSG00000103496.10804.21890604.828600.411003.178802.60670HepG2NELFE
STX4ENSG00000103496.10731.79390563.415900.377102.533601.94000HepG2RECQL
STX4ENSG00000103496.10563.21330383.234200.555404.230403.48510HepG2RPS19
STX4ENSG00000103496.10769.82540477.478300.689005.821904.68500HepG2RPS2
STX4ENSG00000103496.10586.57530370.092500.664308.242007.21870HepG2SAFB2
STX4ENSG00000103496.101032.70740783.335100.398602.110101.51990HepG2SF3A3
STX4ENSG00000103496.10709.20740431.576200.7165011.3411010.17650HepG2SMN1
STX4ENSG00000103496.10697.58610470.969400.566603.471002.38260HepG2SMNDC1
STX4ENSG00000103496.10344.64050582.39210-0.756904.342303.35490HepG2SNRNP70
STX4ENSG00000103496.10860.70740590.573000.543304.797904.21880HepG2SRSF1
STX4ENSG00000103496.101125.52280848.848500.406905.232204.57050HepG2SSB
STX4ENSG00000103496.10668.12380451.193500.566303.601002.84490HepG2SUPV3L1
STX4ENSG00000103496.10825.75720403.769301.0321017.2689016.21410HepG2TIAL1
STX4ENSG00000103496.10544.06260407.436400.417103.540602.92010HepG2TRIM56
STX4ENSG00000103496.10379.19900266.539900.508502.856402.08540HepG2UCHL5
STX4ENSG00000103496.10700.47900413.178200.761504.896203.53950HepG2UPF2
STX4ENSG00000103496.10551.67550670.70450-0.281902.087401.55280HepG2UTP3
STX4ENSG00000103496.10645.62560444.150200.539603.601202.78180HepG2XRN2
STX4ENSG00000103496.10571.08930459.966000.312102.350601.72490HepG2ZC3H8
STX4ENSG00000103496.101213.38520764.035600.6672015.1537014.12890HepG2ZNF622
STX4ENSG00000103496.10800.07500578.034000.468904.024503.23450K562AKAP8L
STX4ENSG00000103496.10771.60310612.686000.332602.661401.57680K562CPEB4
STX4ENSG00000103496.10376.97620256.563200.555103.578402.68720K562CPSF6
STX4ENSG00000103496.10876.90730633.920300.468003.459702.74210K562DDX47
STX4ENSG00000103496.10725.47390567.806300.353402.927002.19100K562EIF2S2
STX4ENSG00000103496.10329.72420221.303200.575102.980302.03050K562FTO
STX4ENSG00000103496.10105.21830222.79740-1.082305.860404.74620K562G3BP2
STX4ENSG00000103496.10425.77040244.941100.797506.347405.14660K562GPKOW
STX4ENSG00000103496.10878.62010572.907700.616806.530804.84160K562HNRNPL
STX4ENSG00000103496.10338.46780239.095600.501302.107401.34250K562METAP2
STX4ENSG00000103496.10784.21980502.095300.643202.725701.74530K562PABPN1
STX4ENSG00000103496.10735.11560573.184900.358902.084301.60050K562PUS1
STX4ENSG00000103496.10507.46180299.524700.760505.044403.93810K562RPS19
STX4ENSG00000103496.10548.86490326.574500.748907.181306.05050K562SRSF1
STX4ENSG00000103496.10329.97610236.249700.481902.309801.36340K562SRSF4
STX4ENSG00000103496.10452.48590330.454400.453301.925301.32860K562TARDBP
STX4ENSG00000103496.10113.82820223.11950-0.971006.316505.11180K562U2AF2
STX4ENSG00000103496.10919.28720649.226000.501705.364104.40010K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for STX4 is not available on ENCORE database.





25 RBPs can affect the splicing of STX4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESTX4ENSG00000103496.10chr16+3105007031050210310498303104996831050861310509720.142000.000000.00000includedHepG2HNRNPK
SESTX4ENSG00000103496.10chr16+310457823104585731045524310456463104629031046361-0.194000.004240.04671excludedHepG2U2AF2
A3SSSTX4ENSG00000103496.10chr16+310455243104564631045546310456463104533331045435-0.602000.000260.08329shorterK562FXR2
A3SSSTX4ENSG00000103496.10chr16+3104552431045646310455463104564631045333310454350.216000.000620.02592longerK562U2AF2
A3SSSTX4ENSG00000103496.10chr16+3104552431045646310455463104564631045333310454350.266000.000000.00000longerK562AQR
A3SSSTX4ENSG00000103496.10chr16+3104980431049968310498303104996831049434310495110.106000.000000.00004longerK562AQR
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.245000.002810.04053includedK562SF3B4
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.184000.000080.00302includedHepG2PCBP2
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.158000.003800.06275includedHepG2PCBP2
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.235000.003810.02467includedK562PUS1
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.189000.000010.00009includedK562PUS1
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.140000.001410.01775includedHepG2SF3A3
RISTX4ENSG00000103496.10chr16+3105104331051489310510433105113931051232310514890.055000.003220.03532includedHepG2SF3A3
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.340000.000000.00000includedHepG2SF3A3
RISTX4ENSG00000103496.10chr16+3105104331051489310510433105113931051232310514890.085000.000370.01162includedK562HNRNPC
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.121000.002200.06559includedHepG2TIA1
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.276000.000000.00003includedHepG2PRPF8
RISTX4ENSG00000103496.10chr16+310455463104585731045546310456463104578231045857-0.174000.000000.00000excludedK562SRSF1
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.158000.000590.00884includedK562AGGF1
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.365000.000010.00037includedK562PRPF8
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.359000.000000.00000includedK562PRPF8
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.100000.000170.00378includedHepG2PCBP1
RISTX4ENSG00000103496.10chr16+3105104331051489310510433105113931051232310514890.090000.000000.00007includedHepG2PCBP1
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.115000.001490.02154includedHepG2PCBP1
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.199000.000020.00050includedHepG2QKI
RISTX4ENSG00000103496.10chr16+310455463104585731045546310456463104578231045857-0.164000.000060.00954excludedK562AARS
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.074000.001970.02099includedHepG2TAF15
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.180000.000000.00005includedHepG2TAF15
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.171000.001390.02638includedHepG2TIAL1
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.154000.000620.00967includedHepG2NCBP2
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.087000.000570.00584includedHepG2SF3B4
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.153000.000010.00020includedHepG2SF3B4
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.337000.000000.00000includedHepG2FUBP3
RISTX4ENSG00000103496.10chr16+3105104331051489310510433105113931051232310514890.054000.000000.00001includedHepG2RBM22
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.126000.000020.00100includedHepG2SRSF9
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.189000.000000.00009includedHepG2SRSF9
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.070000.004440.04502includedHepG2HNRNPK
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.190000.000740.01056includedHepG2HNRNPK
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.121000.000180.00718includedHepG2PTBP1
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.398000.000000.00001includedK562EFTUD2
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.372000.000000.00000includedK562EFTUD2
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.291000.000000.00000includedK562AQR
RISTX4ENSG00000103496.10chr16+3105104331051489310510433105113931051232310514890.089000.000010.00008includedK562AQR
RISTX4ENSG00000103496.10chr16+3104554631045857310455463104564631045782310458570.298000.000000.00000includedK562AQR
RISTX4ENSG00000103496.10chr16+3105086131051139310508613105097231051043310511390.170000.000470.02105includedK562TARDBP
RISTX4ENSG00000103496.10chr16+310455463104585731045546310456463104578231045857-0.142000.000280.00779excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for STX4 is not avaliable on ENCORE database.