SPTBN2

General Information

Gene Name       : SPTBN2
Gene ID             : ENSG00000173898.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SPTBN2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SPTBN2ENSG00000173898.120.060.260.16ENCSR000AEF
HepG2SPTBN2ENSG00000173898.125.151.763.46ENCSR985KAT
K562SPTBN2ENSG00000173898.1224.2313.2718.75ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SPTBN2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SPTBN2 RNA is bound by 12 proteins.  







eCLIP assay for SPTBN2 is not avaliable on ENCORE database.





12 proteins are bound to SPTBN2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116645342266453442-3'-UTR,CDS,intron-Distal3.076883.69775K562YBX3
chr116648872766488778-3'-UTR,5'-UTR,intron-Distal,intron-Proximal5.311917.41223K562SF3B4
chr116646376766463860-CDS,intron-Distal5.889627.89484K562FXR2
chr116645878566458827-CDS,intron-Distal4.848665.24786K562FXR2
chr116645750766457558-CDS,intron-Distal,intron-Proximal4.081883.89948K562YBX3
chr116648156166481595-CDS,intron-Distal,intron-Proximal3.874367.70480K562YBX3
chr116647818166478246-CDS,intron-Distal,intron-Proximal3.392943.65452K562BUD13
chr116645890366458974-CDS,intron-Distal3.981655.82909K562FMR1
chr116648179666481877-CDS,intron-Distal3.188316.54511K562UCHL5
chr116646047166460528-CDS,intron-Distal3.278323.12941K562UCHL5
chr116647639466476458-CDS,intron-Distal3.934013.43253K562YBX3
chr116646817166468208-CDS,intron-Distal4.763694.59551K562FXR2
chr116646856566468636-CDS,intron-Distal3.691296.42513K562YBX3
chr116648156066481616-CDS,intron-Distal,intron-Proximal4.395834.44454K562UCHL5
chr116646128766461330-CDS,intron-Distal5.188386.56513K562FXR2
chr116645722566457278-CDS,intron-Distal,intron-Proximal4.895794.86944K562AQR
chr116646846966468509-CDS,intron-Distal4.769895.24786K562FXR2
chr116648117266481218-CDS,intron-Distal,intron-Proximal3.757126.64581K562YBX3
chr116646069866460756-CDS,intron-Distal5.299337.56146K562FXR2
chr116646622866466273-CDS,intron-Distal,intron-Proximal3.507974.41130K562AQR
chr116649537866495458-intron-Distal4.242664.07596K562GTF2F1
chr116649549066495565-intron-Distal4.292743.17390K562NCBP2
chr116649536766495421-intron-Distal4.369255.36494K562DROSHA
chr116648319966483287-intron-Distal,intron-Proximal3.308433.20886K562PRPF8
chr116645710866457175-intron-Distal4.281204.22101K562PRPF8
chr116646642066466424-intron-Distal,intron-Proximal5.7663310.04245K562AQR
chr116646645166466463-intron-Distal,intron-Proximal5.0157611.03354K562AQR
chr116649535566495444-intron-Distal4.039796.91279K562RBFOX2
chr116647631666476373-intron-Distal,intron-Proximal4.623633.62536K562AQR
chr116649481166494885-intron-Distal3.337184.35933K562RBFOX2
chr116649547566495528-intron-Distal3.812373.25414K562RBFOX2
chr116646642466466451-intron-Distal,intron-Proximal5.9898512.46873K562AQR
chr116645651566456567-intron-Distal,intron-Proximal5.204126.75320K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SPTBN2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SPTBN2 is not available on ENCORE database.

  • 103 RBPs can affect the levels of SPTBN2.  








The Knockdown/knockout RNA-Seq assay for SPTBN2 is not available on ENCORE database.





103 RBPs can affect the gene expression of SPTBN2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SPTBN2ENSG00000173898.7290.17480220.964300.393002.090201.54730HepG2ACO1
SPTBN2ENSG00000173898.7375.65430131.666001.5124011.6347010.61730HepG2AKAP1
SPTBN2ENSG00000173898.7205.48600115.651900.829203.853202.62850HepG2AKAP8
SPTBN2ENSG00000173898.7330.30780222.044900.572903.977203.07040HepG2AKAP8L
SPTBN2ENSG00000173898.7166.61480318.57290-0.935106.599605.72200HepG2BOP1
SPTBN2ENSG00000173898.748.15320103.49680-1.103903.547602.67920HepG2CIRBP
SPTBN2ENSG00000173898.7102.7886057.004200.850402.172301.49890HepG2CNOT7
SPTBN2ENSG00000173898.751.45440101.69370-0.982903.561602.35620HepG2CSTF2
SPTBN2ENSG00000173898.763.39800124.40010-0.972502.655301.76200HepG2DDX24
SPTBN2ENSG00000173898.7282.82280126.104901.165207.744106.74530HepG2DDX3X
SPTBN2ENSG00000173898.7341.57130161.975201.076303.146602.32980HepG2DDX55
SPTBN2ENSG00000173898.7193.68430332.12310-0.778002.637401.68550HepG2DDX59
SPTBN2ENSG00000173898.7163.47150101.359600.689503.387102.67880HepG2DNAJC2
SPTBN2ENSG00000173898.7210.52970104.135601.015505.113604.32220HepG2EIF2S1
SPTBN2ENSG00000173898.7278.80920185.144200.590503.320202.03070HepG2EIF2S2
SPTBN2ENSG00000173898.7193.84110112.070900.790402.788902.09760HepG2EIF4B
SPTBN2ENSG00000173898.7281.68410402.85760-0.516204.071103.36660HepG2ETF1
SPTBN2ENSG00000173898.7341.26560246.381700.469902.049401.38120HepG2FIP1L1
SPTBN2ENSG00000173898.7304.14990116.161101.3886011.073409.77990HepG2FXR1
SPTBN2ENSG00000173898.7184.93860114.406600.692802.656401.78530HepG2G3BP2
SPTBN2ENSG00000173898.7256.00050125.362401.029902.874701.83490HepG2GNB2L1
SPTBN2ENSG00000173898.7211.21400286.96560-0.442202.194501.55020HepG2HNRNPF
SPTBN2ENSG00000173898.792.19160316.41070-1.7791016.4828015.12660HepG2HNRNPLL
SPTBN2ENSG00000173898.7258.53410170.040100.604403.277402.25040HepG2HNRNPM
SPTBN2ENSG00000173898.7167.77070114.060000.556602.404601.83650HepG2HNRNPU
SPTBN2ENSG00000173898.7208.54910125.891700.728102.793801.55680HepG2HSPD1
SPTBN2ENSG00000173898.7168.79720282.58240-0.743403.688702.86370HepG2IGF2BP1
SPTBN2ENSG00000173898.7196.80470102.796700.936902.629901.67300HepG2IGF2BP3
SPTBN2ENSG00000173898.7190.78740110.143400.792502.906401.87580HepG2KHSRP
SPTBN2ENSG00000173898.7231.01410122.885600.910604.558403.09680HepG2LARP7
SPTBN2ENSG00000173898.7356.78960116.840601.6104014.0459012.70360HepG2MATR3
SPTBN2ENSG00000173898.7400.32980199.480401.004809.428708.01840HepG2MSI2
SPTBN2ENSG00000173898.7137.00590322.66100-1.235807.312205.70120HepG2MTPAP
SPTBN2ENSG00000173898.791.87970167.48650-0.866203.880802.43940HepG2NAA15
SPTBN2ENSG00000173898.7229.99710119.583300.943504.854304.02840HepG2NCBP2
SPTBN2ENSG00000173898.7202.32220119.308800.761903.073601.56700HepG2NKRF
SPTBN2ENSG00000173898.7240.91610156.441300.622803.577902.71080HepG2NOL12
SPTBN2ENSG00000173898.7283.50020148.833900.929503.253402.05910HepG2NONO
SPTBN2ENSG00000173898.7111.29900280.54630-1.333809.382908.06510HepG2NSUN2
SPTBN2ENSG00000173898.7105.21320197.28350-0.907005.558204.50160HepG2PRPF4
SPTBN2ENSG00000173898.7402.09730111.802101.8465027.8812026.49660HepG2PTBP1
SPTBN2ENSG00000173898.7278.35290149.345100.898206.310605.45920HepG2PUF60
SPTBN2ENSG00000173898.7281.68670158.546000.829107.066006.20750HepG2PUM1
SPTBN2ENSG00000173898.7150.30780225.07400-0.582503.202702.55170HepG2PUS1
SPTBN2ENSG00000173898.7286.02370124.427001.200703.838103.22120HepG2NELFE
SPTBN2ENSG00000173898.7195.99620115.883200.758103.700103.00110HepG2RECQL
SPTBN2ENSG00000173898.7221.30660309.08380-0.482002.077701.47580HepG2RPLP0
SPTBN2ENSG00000173898.7347.22250125.645201.4664013.3895012.16730HepG2RPS19
SPTBN2ENSG00000173898.7279.57010136.651601.032605.855004.71540HepG2RPS2
SPTBN2ENSG00000173898.7129.2368057.252401.174504.500903.48210HepG2RPS3A
SPTBN2ENSG00000173898.7109.76430237.81570-1.115406.836905.74420HepG2SF3A3
SPTBN2ENSG00000173898.7151.01030313.19380-1.052407.628406.50780HepG2SF3B1
SPTBN2ENSG00000173898.7257.77560116.404701.146908.715607.75690HepG2SF3B4
SPTBN2ENSG00000173898.7195.57200143.218300.449402.003301.38860HepG2SLBP
SPTBN2ENSG00000173898.7283.37540118.441201.2584012.7995011.57360HepG2SMN1
SPTBN2ENSG00000173898.7149.09950348.47950-1.224807.676806.36920HepG2SNRNP70
SPTBN2ENSG00000173898.7255.50880380.28150-0.573704.652804.05240HepG2SRFBP1
SPTBN2ENSG00000173898.7193.24170121.499600.669402.941002.45710HepG2SRSF1
SPTBN2ENSG00000173898.7150.41810336.96990-1.163607.983706.21060HepG2SRSF3
SPTBN2ENSG00000173898.7302.47970147.468001.036309.813608.73040HepG2SRSF5
SPTBN2ENSG00000173898.7159.32610281.92300-0.823305.906004.95160HepG2SRSF7
SPTBN2ENSG00000173898.7193.14550330.14770-0.773404.144103.54350HepG2SSB
SPTBN2ENSG00000173898.7465.47090167.701901.4727024.8482023.29110HepG2SUCLG1
SPTBN2ENSG00000173898.7218.38420123.238100.825302.469001.45780HepG2TBRG4
SPTBN2ENSG00000173898.762.25760100.34850-0.688702.099601.36910HepG2TIA1
SPTBN2ENSG00000173898.7221.08580110.801700.996506.416405.71350HepG2TIAL1
SPTBN2ENSG00000173898.7206.11610111.823200.882105.672404.91740HepG2TRIM56
SPTBN2ENSG00000173898.7376.12280154.463701.283803.807402.81950HepG2UBE2L3
SPTBN2ENSG00000173898.753.2454095.21280-0.838502.783802.02150HepG2UCHL5
SPTBN2ENSG00000173898.782.51440147.54170-0.838403.037301.98460HepG2UPF2
SPTBN2ENSG00000173898.7130.89770203.62130-0.637402.927002.31410HepG2UTP3
SPTBN2ENSG00000173898.781.23950194.68010-1.260908.957407.86550HepG2ZC3H8
SPTBN2ENSG00000173898.71155.556801508.52020-0.384505.537504.77790K562AGGF1
SPTBN2ENSG00000173898.71180.964601657.50040-0.489002.718301.74760K562AKAP8
SPTBN2ENSG00000173898.71144.933401569.65030-0.455204.814903.94540K562AKAP8L
SPTBN2ENSG00000173898.7812.511501634.47030-1.0084016.6751015.39490K562AQR
SPTBN2ENSG00000173898.71172.01200815.040400.523906.694604.52880K562BCCIP
SPTBN2ENSG00000173898.71337.34450787.623000.7637012.9436010.82620K562BCLAF1
SPTBN2ENSG00000173898.7392.69480588.08310-0.582604.156103.08120K562BOP1
SPTBN2ENSG00000173898.7872.87450612.608700.510704.275302.90680K562CCAR1
SPTBN2ENSG00000173898.7936.96610625.268700.583406.360005.17080K562CPSF6
SPTBN2ENSG00000173898.71058.46360597.529400.824805.585104.00210K562CSTF2
SPTBN2ENSG00000173898.7668.785801325.61740-0.987005.354702.75250K562DAZAP1
SPTBN2ENSG00000173898.72014.922201457.052900.467607.977605.90080K562DDX21
SPTBN2ENSG00000173898.71249.990301689.26470-0.434506.598705.15920K562DKC1
SPTBN2ENSG00000173898.71548.917801049.601000.561307.610705.46590K562EXOSC5
SPTBN2ENSG00000173898.7471.81970731.54880-0.632704.131402.71680K562FKBP4
SPTBN2ENSG00000173898.7366.48190636.25860-0.795907.733406.26000K562FMR1
SPTBN2ENSG00000173898.7215.22260329.01330-0.612303.945802.31240K562FUS
SPTBN2ENSG00000173898.782.97290291.97150-1.8151015.5207013.53370K562G3BP2
SPTBN2ENSG00000173898.7502.74510775.63960-0.625604.814203.54950K562HNRNPM
SPTBN2ENSG00000173898.72867.745101680.342800.7711016.1076014.05530K562HNRNPU
SPTBN2ENSG00000173898.7855.753501278.43050-0.579106.078804.91110K562HSPD1
SPTBN2ENSG00000173898.72076.725201457.614200.510604.447502.13930K562IGF2BP1
SPTBN2ENSG00000173898.71074.085001665.90790-0.633208.922407.21760K562KIF1C
SPTBN2ENSG00000173898.7613.69520815.75610-0.410602.696401.33000K562LARP7
SPTBN2ENSG00000173898.7960.53810614.953500.643302.566101.75580K562MAGOH
SPTBN2ENSG00000173898.71167.831301594.58920-0.449402.542401.52700K562MAK16
SPTBN2ENSG00000173898.71092.06760613.597500.831605.349504.00970K562MATR3
SPTBN2ENSG00000173898.71412.135701866.22140-0.402202.713901.81630K562MBNL1
SPTBN2ENSG00000173898.71769.087402471.62290-0.482503.996802.64050K562MSI2
SPTBN2ENSG00000173898.71854.704101550.837800.258002.843802.02430K562MTPAP
SPTBN2ENSG00000173898.7653.812101308.07580-1.0005010.953708.75650K562NAA15
SPTBN2ENSG00000173898.7519.938901122.49770-1.110309.379307.16890K562NCBP2
SPTBN2ENSG00000173898.71327.78800779.030400.769203.326101.88260K562NONO
SPTBN2ENSG00000173898.72407.891201723.073500.4827013.9340012.44130K562NSUN2
SPTBN2ENSG00000173898.71031.42510597.519100.787504.792403.94040K562PTBP1
SPTBN2ENSG00000173898.71960.127502530.00750-0.368203.270602.38490K562PUF60
SPTBN2ENSG00000173898.72025.357802691.28580-0.410105.561804.00520K562PUM1
SPTBN2ENSG00000173898.7724.352501556.90040-1.1039019.1702017.77020K562PUS1
SPTBN2ENSG00000173898.7114.46450278.57410-1.283205.528203.42310K562RAVER1
SPTBN2ENSG00000173898.7911.436101516.76770-0.7348014.0369012.69490K562RBM15
SPTBN2ENSG00000173898.71005.83670688.902100.545905.877504.42730K562RCC2
SPTBN2ENSG00000173898.7970.28800602.618900.687103.300902.09470K562NELFE
SPTBN2ENSG00000173898.71324.202901700.30300-0.360704.506003.48610K562SF3A3
SPTBN2ENSG00000173898.7949.32420674.717400.492504.201602.62100K562SLBP
SPTBN2ENSG00000173898.71026.64210585.847900.809203.462302.67720K562SRSF1
SPTBN2ENSG00000173898.7779.94410476.661200.710305.268103.73250K562SRSF4
SPTBN2ENSG00000173898.7872.74260553.487300.656902.582501.57370K562SRSF5
SPTBN2ENSG00000173898.71681.293901300.180000.370805.081203.47690K562SRSF7
SPTBN2ENSG00000173898.7725.539601027.16080-0.501505.616004.43810K562SYNCRIP
SPTBN2ENSG00000173898.7137.62230286.60370-1.058305.107502.87500K562TAF15
SPTBN2ENSG00000173898.71026.89760592.743900.792703.472802.67630K562TARDBP
SPTBN2ENSG00000173898.71038.13900571.813700.860306.354805.04150K562TIA1
SPTBN2ENSG00000173898.7995.58470725.888600.455703.225002.20810K562TIAL1
SPTBN2ENSG00000173898.7839.37890561.527500.579902.793301.69530K562TRA2A
SPTBN2ENSG00000173898.7144.23190283.00520-0.972406.089504.32610K562U2AF1
SPTBN2ENSG00000173898.7149.40470292.28600-0.968207.804806.44670K562U2AF2
SPTBN2ENSG00000173898.7932.712601578.29410-0.758904.274702.54090K562UTP18
SPTBN2ENSG00000173898.71389.448601625.70550-0.226602.549201.73440K562WDR43
SPTBN2ENSG00000173898.71563.749201936.62730-0.308502.682201.41650K562WRN
SPTBN2ENSG00000173898.71395.80660801.755500.799802.507501.37400K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SPTBN2 is not available on ENCORE database.





2 RBPs can affect the splicing of SPTBN2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESPTBN2ENSG00000173898.7chr11-664888206648891166488554664887336649621166496430-0.343000.001160.03558excludedK562AKAP8L
SESPTBN2ENSG00000173898.7chr11-664888206648891166488554664887336649621166496430-0.365000.001920.04467excludedK562RBM15

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SPTBN2 is not avaliable on ENCORE database.